The
NMR centre is
situated in the Conway Institute at University College Dublin.
It is funded by the Wellcome Trust, SFI, PRTLI-3 and PRTLI-4. The NMR will be used for biochemical and biomedical research. It is hoped that these studies will help in the understanding and treatment of a range of medical conditions including Cancer, AIDS, parasitic diseases, neurodegenerative disorders, diabetes, arthritis and heart disease.
ICMRBS 2018 at UCD
EUROMAR 2012
at
The facility has standard bore 300 and 500 MHz Bruker NMR spectrometers and a Varian 600MHz NMR spectrometer as well as a wide range of probes, equipment and software which can be used to study 1H, 2H, 13C, 31P, 15N and 19F in liquid and solid biological samples.
This facility does not specialise in the determination of the 3D-structures of proteins. There are however several large NMR groups which specialise in determining the structures of proteins.
However, we do intend to determine the structure of peptides (approx. 30 amino acid residues) and ligands such as peptide inhibitors (Mr ~2000) attached to proteins.
We focus on a range of research areas where NMR offers a unique non-invasive method for investigating biological systems. Check up on the NMR installation and move to the Conway Institute.
Projects
under the direction
of
Professor J.P.G. Malthouse, Dr G.J.
McBean, Dr C. Hewage and Professor L. Brennan include:-