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Nanoparticle synthesis, functionalisation and dispersion

Access to high quality, high purity nanoparticles, functionalised to enable visualisation, cellular or sub-cellular targeting, that are well dispersed under the relevant exposure conditions and stable (or well characterised) over the exposure period, is critical to quantitative bionanointeractions studies.

Within this theme, researchers are developing new approaches to address a range of these issues including:

  • Labelling of nanoparticles in ways that ensures no dye leaks from the particles;
  • Functionalisation of nanoparticles with proteins oriented correctly to interact with their target receptors;
  • Synthesis of nanoparticles with pH-variable and pH-invariable surface charge densities;
  • Novel approaches to disperse nanoparticles using biocompatible / biological agents.