Professor Wenxin Wang, BSc, MSc, Ph.D., FRSC

Science Foundation Ireland (SFI) Principal Investigator, UCD Charles Institute of Dermatology 
Senior Lecturer (Skin Research and Wound Healing), UCD School of Medicine & Medical Science

Research Expertise

• Macromolecular design and engineering via controlled/living polymerisation techniques (including ATRP, RAFT and ROP) and click chemistry
• Functional nanomaterials - knot and/or dendritic polymers as multifunctional carriers for targeted therapeutic drugs (proteins and peptides) and DNA/RNA delivery
• Skin gene therapy and the development of new DNA plasmid vectors
• Bio-inspired responsive polymers as dressing/adhesive for wound healing
• Injectable ECM biopolymer hybrid hydrogels for stem cells encapsulation and delivery
• 3D Bio-printing
• Clinical targets: Epidermolysis bullosa, diabetic skin wound healing, Parkinson's and cardiovascular disease

Keywords

Polymer synthesis, gene therapy, cell therapy, recessive dystrophic epidermolysis bullosa, diabetic wound healing, skin regeneration, cardiovascular disease, Parkinson's disease, stem cells, injectable hydrogels, hyperbranched polymers

Team 

Professor Wenxin Wang’s team currently comprises 4 senior researchers (research fellows and postdoctoral fellows) and 13 PhD students

Postdoctoral Fellows

Udo Greiser	Dr Udo Greiser, Senior Researcher/ Research Fellow

Project: ‘Delivery of Type VII Collagen Gene (COL7A1) for Topical Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)’
Funding: Health Research Board - Health Research Award (obtained by PI Dr. Wenxin Wang)

 

 

Yixiao DongDr Yixiao Dong, Research Fellow

Project: ‘Skin substitute from in-situ formed stem cell encapsulated hydrogel for diabetic wound repair ’
Funding: Irish Research Council (IRC) ELEVATE Fellowship

 

 



Dezhong Zhou	Dr Dezhong Zhou

Project: ‘A new generation of safe and efficient non-viral gene delivery vectors’
Funding: Science Foundation Ireland (SFI) Technology Development Award (TIDA)

 

 

 

Wei Wang	Dr Wei Wang, Senior Researcher/ Postdoctoral Researcher

Project: ‘Development and Delivery of Nonviral S/MAR Minicircles for Long-term Type VII Collagen Gene expression for the Treatment of Recessive Dystrophic Epidermolysis Bullosa’
Funding: Science Foundation Ireland Investigators Award 2012

Graduates

Fatma Alshehri

Project: ‘Wound healing and gene therapy for recessive dystrophic epidermolysis bullosa’
Funding: Saudi Arabia Government PhD Fellowship.

Sigen A

 

 

Sigen A

Project: ‘In situ formed hydrogel scaffold combining stem cell for Wound Healing’
Funding: Science Foundation Ireland (SFI) Investigators Award 2013

 

Ligia Bre

 

Ligia Bre

Project: ‘Anti-Fouling of Bioprosthetic Heart Valves to Inhibit Tissue Calcification’
Funding: Irish Research Council Employment-Based Postgraduate Programme award and by Boston Scientific Ireland

 

 

Lara Cutler

 

Lara Cutlar 

Project: ‘A topically delivered episomal non viral gene therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB)’
Funding: Through SFI Principal Investigator award to Dr Wenxin Wang

 

 

 

Patrick Duffy	Patrick Duffy

Project: ‘Stem Cell based Hydrogel for Wound Healing’
Funding: Scholarship by Vornia Biomaterials Ltd.

 

 

 

 

Yongsheng Gao	Yongsheng Gao

Project: ‘New Generation of Multifunctional Biomaterials from Controlled/Living Polymerization of Multivinyl Monomers’
Funding: UCD School of Medicine and Medical Science PhD Fellowship

 

 

 

 

Zehua Li	Zehua Li

Project: ‘Multi-functional dendritic polymers for cell delivery and angiogenesis’
Funding: Science Foundation Ireland and Vornia Biomaterials Ltd.

 

 

 

 

Sean McMahon	Sean McMahon

Project: ‘Development of Reinforced biodegradable polymers for application as a cardiac stent' 
Funding: Irish Research Council Employment based Postgraduate Fellowship

 

 

 

 

Jonathan O'Keefe-AhernJonathan O’Keefe-Ahern

Project: ‘Gene Therapy for the Treatment of Recessive Dystrophic Epidermolysis Bullosa’
Funding: Science Foundation Ireland (SFI) Investigators Award 2013

 

 

 

 

Qian Xu	Qian Xu

Project: ‘In situ Formed Skin Substitute in Combination with Gene Therapy for Wound Healing’
Funding: Science Foundation Ireland (SFI) Investigators Award 2013

 

 

 

 

Yue Qin	Yue Qin

Project: ‘Delivery of Type VII Collagen Gene (COL7A1) for Topical Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)’
Funding: Science Foundation Ireland (SFI) Investigators Award 2013

 

 

 

 

Tianyu ZhaoTianyu Zhao (joint with Vicky Zhang)

Project: ‘In situ formed Stem Cell Biological Dressing for Wound Healing’
Funding: Through SFI Principal Investigator award to Dr Wenxin Wang

 

 

 

 

Hong ZhangVicky Zhang (joint with Tianyu Zhao)

Project: ‘In situ formed Stem Cell Biological Dressing for Wound Healing’
Funding: Through SFI Principal Investigator award to Dr Wenxin Wang 

 

 

 

Visiting Researchers

‌Shuai Liu

Visiting 1st year guest PhD student, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin, China
Project: ‘Multifunctional bioreducible highly branched poly(β-amino ester)s with enhanced cell-penetrating for gene delivery’

Xuan Wei

Master's student, Shanghai Jiao Tong University, Shanghai, China
Project: 'Kinetically Controlled Homopolymerization of Trivinyl Monomers: toward Single Chain Cyclized Polymers'.