Synthesis: Small Molecules – Natural Products

  • Synthesis of P-Chiral Drugs and P-based agrichemicals
  • Anti-HIV “ProTide” (Gilead)
  • New methods for the synthesis of molecules with biological interest. Synthesis of falcarinol present in carrots/parsnips and ginseng - biological profile is of interest
  • Design, synthesis and evaluation of potential anti-inflammatory agents and synthesis of natural products
  • Small molecule synthesis for biological applications: Amino acids or dipeptides with anti-bacterial/anti-fungal activity Rigid non-natural amino acid for incorporation into di/oligo-peptides with anti cancer properties
  • Synthesis of biologically active saccharides and glycoconjugates towards novel drugs and vaccines
  • Organocatalysts for carbohydrate synthesis
  • Synthesis of alpha-Thiosugars – development of methodology and synthesis of glycodrugs
  • N-heterocyclic – gold-based anticancer drugs against difficult to treat breast and renal cell cancer