UCD School of Chemistry & Chemical Biology

Scoil na Ceimice agus na Ceimbhitheolaíochta UCD

Dr Vitaly Buckin MSC PhD

Contact Details

Title	Senior Lecturer
Address	School of Chemistry & Chemical Biology Science Centre Belfield Dublin 4
Telephone:	Ext. 2371
Email:	ei.dcu@nikcub.ylativ

Biography:

Academic positions:

1996-present
Lecturer, School of Chemistry and Chemical Biology, University College Dublin, Head of Laboratory of Physical Chemistry of Biocolloids

1994-1996
Research faculty staff at Department of Chemistry New York University, USA

1990-1994
Research Fellow at Max-Planck-Institute for Biophysical Chemistry, Goettingen, Germany

1978-1990
Scientist - Senior Scientist at Institute of Biological Physics Academy of Science of Russia

Education:

1984,
PhD. in Biological Physics, from Institute of Biological Physics (Russian Academy of Sciences)

1978,
BSc. and MSc. in Physics/Biological Physics (first class honour), Lomonosov Moscow State University

1972,
Diploma from Advanced Kolmogorov School of Mathematics and Physics (Lomonosov Moscow State University) of Russia

Research Interests

Main research areas:

Physical chemistry of biocolooids:

Organisation and functioning of biocolloids, biopolymers, nanoassemblies (protein nano-particles, surfactants micelles, microemulsions), conformational and phase transitions in biocolloids; hydration effects in biopolymers and in nanoaggregates, encapsulation of active compounds in industrial formulations, elasticity of biopolymers and nanoaggregates and gels.

Ultrasonic spectroscopy and high-frequency dynamic rheology
Application of high -resolution measurements of velocity and attenuation of ultrasonic longitudinal and shear waves for analysis of microstructural organization, particle sizing, sedimentation and creaming phenomena, ligand binding and surface adsorption, conformation transitions of polymers and biocolloids, monitoring of biocatalysis in complex colloid systems and matrixes, aggregation, gelation and crystallisation processes. High-frequency viscoelasticity of emulsions, suspensions and gels.

Technology transfer: for product development, QA/QC and optimization of technological processes in both of R&D development and industrial environments.

Representative projects in the field of physical chemistry of biocolooids:

Inhaler drug formulations. Optimization of inhaling dispersions.
Microencapsulation of anticancer drugs, quality control of emulsions/microemulsion based formulations.
Ultrasonic monitoring of enzyme reactions in complex media. Ultrasonic enzyme screening in food matrixes.
Development of heat stable of calcium enriched milks.
Technologies for spreadable butter and mouthfeel of low fat milks.edimentation and creaming in pharmaceutical emulsions. Effect of stabilizers (e.g. coating polymers) on rate of aggregation and particle size.
Surfactant encapsulation of DNA fragments
Casein 'chaperones' for control of heat induced aggregation of milk proteins

Ultrasonic spectroscopy
Our proprietary patented ultrasonic technology commercialised in 2002 is employed in the range of High-Resolution Ultrasonic Spectrometers (HR-US) for analysis of molecular transformations and microstructural characterisation. The HR-US spectrometers are currently used in Biotechnology, Pharmaceutical, Food, Personal Care, Chemicals, Petrochemistry, and other industries and academic research worldwide.
Section 'Professional/Other' provides representative publications of academic research groups utilising HR-US spectrometers.

Funding History:
Over 4M Euro national and international research funding to University in the last 10 years.

Research Projects

Sponsor : Irish Research Council for Science Engineering and Technology (IRCSET)
Title : Self-assembly of hyaluronan-amino acids bio-active nano-aggregates
Start Date / End Date : 15-OCT-10 / 14-OCT-13

Sponsor : Irish Research Council for Science Engineering and Technology (IRCSET)
Title : Application of HR (high resoluttion) Ultrasonic Spectroscopy for Monitoring Enzymatic Reactions in Simple and Complex Media
Start Date / End Date : 01-OCT-07 / 01-SEP-09

Sponsor : Science Foundation Ireland (SFI)
Title : New Ultrasonic method for analysis of phase diagrams and nano-structural characterisation of microemulsion systems
Start Date / End Date : 01-JUL-07 / 31-MAR-12

Sponsor : Dept. of Agriculture, Food & Rural Development
Title : The Use of Novel Methods and New Processing Technology for the Development of Heat Stable Dairy Ingredients
Start Date / End Date : 01-JAN-01 / 31-DEC-03

Sponsor : Enterprise Ireland (EI)
Title : Longitudinal and short wave spectroscopy for analysis of food colloids
Start Date / End Date : 01-OCT-00 / 30-SEP-02

Sponsor : Teagasc Title : Development of acoustical methods to predict that the eating quality of beef has been approved Start Date / End Date : 01-OCT-98 / 30-SEP-98
Sponsor : Enterprise Ireland (EI) Title : Improved Mouthfeel of Low Fat Milk Start Date / End Date : 01-APR-98 / 31-MAR-20
Sponsor : Enterprise Ireland (EI) Title : Spreadable Butter Start Date / End Date : 01-APR-98 / 31-MAR-20
Sponsor : Dept. of Agriculture, Food & Forestry Title : Routine diagnostic tests for food pathogens Start Date / End Date : 01-SEP-97 / 31-DEC-99
Sponsor : Dept. of Agriculture, Food & Forestry Title : Development of acoustic methods to predict eating quality of beef Start Date / End Date : 01-OCT-97 / 31-DEC-99
Sponsor : Dept. of Agriculture, Fisheries & Food (DAFF) Title : Controlling aggregation of food protein particles Start Date / End Date : 01-OCT-06 / 30-SEP-09
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Peer Reviewed Journals

Resa, Pablo,Buckin, Vitaly; (2011) 'Ultrasonic analysis of kinetic mechanism of hydrolysis of cellobiose by [beta]-glucosidase'. Analytical Biochemistry, 415 (1):1-11.

[DOI] [Details]

Hickey, S,Hagan, SA,Kudryashov, E,Buckin, V; (2010) 'Analysis of phase diagram and microstructural transitions in an ethyl oleate/water/Tween 80/Span 20 microemulsion system using high-resolution ultrasonic spectroscopy'. International Journal of Pharmaceutics, 388 :213-222. [DOI] [Details]

Ochenduszko, A,Buckin, V; (2010) 'Real-Time Monitoring of Heat-Induced Aggregation of beta-Lactoglobulin in Aqueous Solutions Using High-Resolution Ultrasonic Spectroscopy'. International Journal Of Thermophysics, 31 :113-130. [DOI] [Details]

Resa, P.,Kudryashov, E.,Buckin, V.; (2009) 'Direct real time monitoring of cellulose saccharification using high-resolution ultrasonic spectroscopy'. New Biotechnology, 25 .

[Details]

Buckin, V.,Resa, P.,Kudryashov, E.; (2009) 'Ultrasonic enzyme assays. Real time monitoring of enzyme reactions in solutions and complex media using high-resolution ultrasonic spectroscopy'. New Biotechnology, 25 .

[Details]

Oliynyk, V.,Jager, M.,Heimburg, T.,Buckin, V.,Kaatze, U.; (2008) 'Lipid membrane domain formation and alamethicin aggregation studied by calorimetry, sound velocity measurements, and atomic force microscopy'. Biophysical Chemistry, 134 (33):168-177168. [Details]
O'Driscoll, B; Buckin, V; ; (2006) 'A colloid stability analyzer for the analysis of stability of complex formulation'. American Laboratory, 38 (9):18-19. [Details]
Hickey, S.,Lawrence, M. J.,Hagan, S. A.,Buckin, V.; (2006) 'Analysis of the phase diagram and microstructural transitions in phospholipid microemulsion systems using high-resolution ultrasonic spectroscopy'. Langmuir, 22 (1313):5575-55835575. [Details]
Smyth, C; O'Driscoll, B; Lawrence, J; Hickey, S; O'Reagan, T; Buckin, V; ; (2005) 'High-resolution ultrasonic spectroscopy: Analysis of microemulsions'. Spectroscopy, 20 (2):44-49. [Details]
Jager, M; Kaatze, U; Kudryashov, E; O'Driscoll, B; Buckin, V; ; (2005) 'New capabilities of high-resolution ultrasonic spectroscopy: Titration analysis'. Spectroscopy, 20 (10). [Details]
Vitaly Buckin and Elizabeth Craig; (2005) 'New Applications of High Resolution Ultrasonic Spectroscopy for Real Time Analysis of Enzymatic Proteolysis'. European BioPharma Review, :50-53. [Details]
Smyth, C.,Kuryashov, E.,O'Driscoll, B.,Buckin, V.; (2005) 'Sound spectroscopy: ultrasonic spectroscopy is a useful tool for the dairy industry'. Dairy Industries International, 70 (44). [Details]
Van Durme, K.,Delellio, L.,Kudryashov, E.,Buckin, V.,Van Mele, B.; (2005) 'Exploration of high-resolution ultrasonic spectroscopy as an analytical tool to study demixing and remixing in poly(N-isopropyl acrylamide)/water solutions'. Journal of Polymer Science Part B-Polymer Physics, 43 (1111):1283-12951283. [Details]
Van Durme, K.,Delellio, L.,Kudryashov, E.,Buckin, V.,Van Mele, B.; (2005) 'Exploration of high-resolution ultrasonic spectroscopy as an analytical tool to study demixing and remixing in poly(N-isopropyl acrylamide)/water solutions'. Journal of Polymer Science Part B-Polymer Physics, 43 (11):1283-1295. [Details]
Smyth, C.,O'Driscoll, B.,Lawrence, J.,Hickey, S.,O'Reagan, T.,Buckin, V.; (2005) 'High-resolution ultrasonic spectroscopy: Analysis of microemulsions'. Spectroscopy, 20 (22):44-4944. [Details]
Smyth, C.,Kudryashov, E.,O'Driscoll, B.,Buckin, V.; (2005) 'Sound spectroscopy: ultrasonic spectroscopy is a useful tool for the dairy industry'. Dairy Industries International, 70 (44). [Details]
Lehmann, L.,Buckin, V.; (2005) 'Determination of the heat stability profiles of concentrated milk and milk ingredients using high resolution ultrasonic spectroscopy'. Journal of Dairy Science, 88 (99):3121-31293121. [Details]
Lehman, L.,Buckin , V.; (2005) 'Application of High Resolution Ultrasonic Spectroscopy for the Analysis of the Heat Stability of Milk'. Intl. Labmate, 5 :10-1110. [Details]
Kudryashov, E., Smyth, C., Oâ¿¿Driscoll B., Buckin, V.; (2005) 'High Resolution Ultrasonic Spectroscopy for the Analysis of Raw Material and Formulations Used In Pharmaceutical Industry'. Pharma Tech Europe, (66):40-4540. [Details]
Jager, M.,Kaatze, U.,Kudryashov, E.,O'Driscoll, B.,Buckin, V.; (2005) 'New capabilities of high-resolution ultrasonic spectroscopy: Titration analysis'. Spectroscopy, 20 (1010):24-24. [Details]
Dwyer, C.,Donnelly, L.,Buckin, V.; (2005) 'Ultrasonic analysis of rennet-induced pre-gelation and gelation processes in milk'. Journal of Dairy Research, 72 (33):303-310303. [Details]
Kudryashov, E.,Smyth, C.,O'Driscoll, B.,Buckin, V.; (2005) 'Analysing raw materials and formulations using high-resolution ultrasonic spectroscopy'. Pharmaceutical Technology Europe, 17 (66):40-45. [Details]
Smyth, C.,Kudryashov, E.,O'Driscoll, B.,Rogueda, P.,Lawrence, J.,Hickey, S.,Buckin, V.; (2005) 'New applications of high-resolution ultrasonic spectroscopy for analysis of molecular processes in pharmaceutical research and industry'. Journal of Pharmacy and Pharmacology, 57 . [Details]
Lehmann, L; Buckin, V; ; (2005) 'Determination of the heat stability profiles of concentrated milk and milk ingredients using high resolution ultrasonic spectroscopy'. Journal of Dairy Science, 88 (9):3121-3129. [Details]
Polacek, R; Buckin, VA; Eggers, F; Kaatze, U; ; (2004) 'Kinetics of base-stacking interactions and proton exchange of 6-methylpurine aqueous solutions'. Journal of Physical Chemistry A, 108 (10):1867-1872. [Details]
L. Lehmann, E. Kudryashov and V. Buckin; (2004) 'Ultrasonic Monitoring of the gelatinisation of starch'. Progress in Colloid and Polymer Science, 123 :136-140. [Details]
Dwyer, C.,Smyth, C.,Kudryashov, E.,Buckin, V.; (2004) 'High-resolution ultrasonic spectroscopy for real time analysis of chemical reactions'. Journal of Pharmacy and Pharmacology, 56 . [Details]
Smyth, Cormac,Kudryashov, Evgeny,O'Driscoll, Breda,Buckin, Vitaly; (2004) 'High-resolution ultrasonic spectroscopy for analysis of industrial emulsions and suspensions'. Journal of the Association for Laboratory Automation, 9 (22):87-9087. [Details]
Hickey, S; Buckin, V; Ivanitskii, GR; Lawrence, MJ; ; (2004) 'Investigation of pharmaceutical biocolloids using high-resolution ultrasonic spectroscopy'. Abstracts of Papers of the American Chemical Society, 228 (NA):463-463. [Details]
O'Driscoll, Breda,Kudryashov, Evgeny,Buckin, Vitaly; (2004) 'Future determination of biochemical monitoring using high-resolution ultrasonic spectroscopy'. American Biotechnology Laboratory, 22 (11):26-2726. [Details]
Lehmann, L.,Kudryashov, E.,Buckin, V.; (2004) 'Ultrasonic monitoring of the gelatinisation of starch'. Trends in Colloid and Interface Science Xvi, 123 :136-140136. [Details]
Lehman, L.,Buckin, V.; (2004) 'Use of HR-US for the analysis of the heat stability of milk'. European Dairy Magazine, (66):14-1514. [Details]
Dwyer, C., Smyth, C., Kudryashov, E., Buckin, V.; (2004) 'High-Resolution Ultrasonic Spectroscopy for Real Time Analysis of Chemical Reactions'. BPC (British Pharma Conference), . [Details]
Dwyer, C., Smyth, C., Kudryashov, E., Buckin, V.; (2004) 'High Resolution Ultrasonic Spectroscopy for the analysis of food colloids'. Food Science Conference, . [Details]
Buckin, V.,Smyth, C.,Dwyer, C.,Kudryashov, E.; (2004) 'Real time analysis of chemical reactions with high-resolution ultrasonic spectroscopy'. Abstracts of Papers of the American Chemical Society, 227 . [Details]
Buckin, V., Kudryashov, E., O' Driscoll, B.; (2004) 'The New Wave of Titration Analysis â¿¿ The Ultrasonic All Chemical Reaction Analyser'. Business Briefing: PharmaTech, (11):1-41. [Details]
Dunne, C; Buckin, V; ; (2004) 'Structure of DNA-DTAB complexes'. Abstracts of Papers of the American Chemical Society, 228 (NA):463-463. [Details]
Kudryashov, E; Smyth, C; O'Driscoll, B; Buckin, V; ; (2003) 'High-resolution ultrasonic spectroscopy for analysis of chemical reactions in real time'. Spectroscopy, 18 (10). [Details]
Smyth, C.,Kudriashov, E.,O'Driscoll, B.,Buckin, V.; (2003) 'Sounding out pharmaceutical processes'. JALA - Journal of the Association for Laboratory Automation, 8 (44):46-4946. [Details]
Buckin, V.,O'Driscoll, B.,Smyth, C.,Alting, A. C.,Visschers, R. W.; (2003) 'Ultrasonic spectroscopy for material analysis. Recent advances'. Spectroscopy Europe, 15 (11):20-2520. [Details]
Buckin, V., Kudryashov, E., Morrissey, S., O' Driscoll B.; (2003) 'Hochauflosende Ultraschallspektroskopie fur die Analyse von Biokolloiden'. LABO, (33):11-1311. [Details]
Smyth, C., Kudryashov, E., O' Driscoll, B., Buckin, V.; (2003) 'Ultrasonic Spectroscopy: a New Window on Pharma Materials'. Pharmaceutical Visions, (22). [Details]
Smyth, C., Kudryashov, E., O' Driscoll B., Buckin V.; (2003) 'Sounding Out Pharmaceutical Processes Using Ultrasonic Spectroscopy'. Lab Update, (66):11-1211. [Details]
Smyth, C., Kudryashov, E., O' Driscoll B., Buckin, V.; (2003) 'Sound out ultrasonic spectroscopy in the pharmaceutical processes'. E-Lab, (66):35-3835. [Details]
O'Driscoll, B.,Smyth, C.,Alting, A. C.,Visschers, R. W.,Buckin, V.; (2003) 'Recent applications for high-resolution ultrasonic spectroscopy'. American Laboratory, 35 (33):54-54. [Details]
Smyth, C.,Kuryashov, E.,O'Driscoll, B.,Buckin, V.; (2003) 'The new wave of analysis'. Chemistry and Industry (London), (2424):2-32. [Details]
Masulis, IS; Buckin, VA; Ozoline, ON; ; (2002) 'Flexible elements in the structure of promoter DNA as probed by cationic surfactant binding'. Journal of Biomolecular Structure &Amp; Dynamics, 19 (5):919-927. [Details]
Buckin, V., and Kudryashov, E.; (2002) 'Supersonic High Resolution Ultrasonic Spectroscopy'. Biochemist, 8 :25-2725. [Details]
Buckin, V., Kudryashov, E., O' Driscoll, B.; (2002) 'An Alternative Spectroscopy Technique for Biopharmaceutical Applications'. Pharma Tech Europe, 12 :33-3733. [Details]
Masulis, I. S.,Buckin, V. A.,Ozoline, O. N.; (2002) 'Flexible elements in the structure of promoter DNA as probed by cationic surfactant binding'. Journal of Biomolecular Structure & Dynamics, 19 (55):919-927919. [Details]
Buckin, W.,Kudryashov, E.,O'Driscoll, B.; (2002) 'Spectroscopy Perspectives- High-resolution ultrasonic spectroscopy for material analysis'. American Laboratory, (33):28-3128. [Details]
Buckin, V. ,Kudryashov, E.; (2002) 'Hochauflosende Ultraschallspektroskopie fur die Analytik'. LaborPraxis, 9 :68-7468. [Details]
Buckin, V., Kudryashov E., Oâ¿¿Driscoll, B.; (2002) 'The Mastery of Sound -High Resolution Ultrasonic Spectroscopy for analysis of chemical reactions'. Lab News, (33):9-259. [Details]
Buckin, V., and Kudryashov, E.; (2002) 'Echo-Nomical Testing'. Polymers Paint Color Journal, 9 :10-1410. [Details]
Buckin, V., Kudryashov, E., Morrissey, S., Smyth, C., O' Driscoll, B.; (2002) 'HRUS for analysis of biocolloids'. Intl. Labmate, (44):23-2423. [Details]
Buckin V., O'Driscoll B.; (2002) 'Ultrasonic waves and material analysis: recent advances and future trends'. Lab Plus Int, 16 (33):17-2117. [Details]
Buckin, V.,Smyth, C.; (2002) 'Making waves'. Dairy Industries International, 67 (88):15-1615. [Details]
Buckin, V.,Kudryashov, E.,O'Driscoll, B.; (2002) 'An alternative spectroscopy technique for biopharmaceutical applications'. Pharmaceutical Technology Europe, 14 (1212). [Details]
Buckin, V.,Kudryashov, E.,O'Driscoll, B.; (2002) 'High-resolution ultrasonic spectroscopy for material analysis'. American Laboratory, 34 (5 SUPPL.5 SUPPL):28-3128. [Details]
Kudryashov, E.,O'Driscoll, B.,Buckin, V.; (2002) 'New analytical technique uses ultrasonic spectrometry'. Paint and Coatings Industry, 18 (1111):60-6660. [Details]
Craig, BM; Dunne, C; Kudryashov, ED; Morrissey, S; Buckin, V; ; (2001) 'Micelles on the surface of DNA. Structure and thermodynamic properties'. Biophysical Journal, 80 (1):481-482. [Details]
Smyth, C.,Kudryashov, E. D.,Buckin, V.; (2001) 'High-frequency shear and volume viscoelastic moduli of casein particle gel'. Colloids and Surfaces a-Physicochemical and Engineering Aspects, 183 :517-526517. [Details]
Kudryashov, E.,Smith, C.,Buckin, V.; (2001) 'Ultrasonic spectroscopy for measurements of dynamics and viscoelasticity of protein aggregates and gels'. Biophysical Journal, 80 (11). [Details]
Kankia, B. I.,Buckin, V.,Bloomfield, V. A.; (2001) 'Hexamminecobalt(III)-induced condensation of calf thymus DNA: circular dichroism and hydration measurements'. Nucleic Acids Research, 29 (1313):2795-28012795. [Details]
Buckin , V.; (2001) 'Physical Chemistry of Biocolloids at UCD'. The Irish Scientists, 111 (33). [Details]
Buckin, V., Kudryashov, E., Smyth, C.; (2001) 'High-Resolution ultrasonic spectroscopy for complex colloids'. Proceedings of 1st International conference on dielectric spectroscopy in physical, chemical and biological applications, March 12-15, Jerusalem (Israel), . [Details]
Buckin, V., Kudryashov, E., Smyth, C.; (2001) 'Ultrasonic Spectroscopy for LC Analysis'. Proceedings of Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, New Orleans, . [Details]
Buckin, V.,Kudryashov, E.; (2001) 'Ultrasonic shear wave rheology of weak particle gels'. Advances in Colloid and Interface Science, 89 :401-422401. [Details]
Kudryashov, E. D.,Hunt, N. T.,Arikainen, E. O.,Buckin, V. A.; (2001) 'Monitoring of acidified milk gel formation by ultrasonic shear wave measurements. High-frequency viscoelastic moduli of milk and acidified milk gel'. Journal of Dairy Science, 84 (22):375-388375. [Details]
Kankia, BI; Buckin, V; Bloomfield, VA; ; (2001) 'Hexamminecobalt(III)-induced condensation of calf thymus DNA: circular dichroism and hydration measurements'. Nucleic Acids Research, 29 (13):2795-2801. [Details]
Kudryashov, E; Smith, C; Buckin, V; ; (2001) 'Ultrasonic spectroscopy for measurements of dynamics and viscoelasticity of protein aggregates and gels'. Biophysical Journal, 80 (1):413-413. [Details]
Morrissey, S. and Cragg, B. and Buckin, V. A.,; (2000) 'Does the structure of surfactant complexes on the surface of DNA depend on the nucleotide sequence?'. PROGRESS IN COLLOID AND POLYMER SCIENCE, . [Details]
Smyth, Cormac,Kudryashov, Evgeny,Buckin, Vitaly; (2000) 'High-resolution longitudinal and shear wave spectroscopy for analysis of complex colloids'. The Journal of the Acoustical Society of America, 107 (55):2865-28662865. [Details]
Buckin, V.; (2000) 'Progress in colloid and polymer science: Preface'. Progress in Colloid and Polymer Science, 115 . [Details]
Dwyer, C.,Allen, P.,Buckin, V.; (2000) 'Temperature dependence of the ultrasonic parameters of bovine muscle: Effects of muscle anisotropy'. Progress in Colloid and Polymer Science, 115 :282-286282. [Details]
Morrissey, S.,Craig, E.,Buckin, V.; (2000) 'Does the structure of surfactant complexes on the DNA surface depend on the nucleotide sequence?'. Progress in Colloid and Polymer Science, 115 :201-208201. [Details]
Smyth, C., Kudryashov, E., Buckin, V.; (2000) 'High-resolution ultrasonic resonator measurements for analysis of weak gels'. Proceeding of Symposium on Surfactant Self-assemblies: Structure, dynamics and reactions, Uppsala (Sweden), . [Details]
Kudryashov, E.,Smyth, C.,Duffy, G.,Buckin, V.; (2000) 'Ultrasonic high-resolution longitudinal and shear wave measurements in food colloids: monitoring of gelation processes and detection of pathogens'. Trends in Colloid and Interface Science Xiv, 115 :287-294287. [Details]
Hunt, N.,Buckin, V.; (2000) 'Temperature dependence and the effects of heat treatment on the rheological properties of various butters'. Progress in Colloid and Polymer Science, 115 :320-324320. [Details]
Buckin, V., Kudryashov, E., Smyth, C.; (2000) 'High-resolution ultrasonic resonator measurements for analysis of complex colloids'. Proceedings of Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, New Orleans, . [Details]
Buckin, V.,Morrissey, S.,Craig, E.; (2000) 'Binding of surfactants to double stranded oligonucleotides. Effect of nucleotide sequence'. Biophysical Journal, 78 (11). [Details]
Will, G; Kudryashov, E; Duggan, E; Fitzmaurice, D; Buckin, V; Waghorne, E; Mukherjee, S; ; (1999) 'Excited state complex formation between 3-aminophthalhydrazide and DNA: a fluorescence quenching reaction'. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy, 55 (13):2711-2717. [Details]
Smyth, C.,Dawson, K.,Buckin, V. A.; (1999) 'Ultrasonic analysis of heat-induced coagulation in calcium fortified milk'. Trends in Colloid and Interface Science Xiii, 112 :221-226221. [Details]
Morrissey, S.,Kudryashov, E. D.,Dawson, K. A.,Buckin, V. A.; (1999) 'Surfactant-DNA complexes in low ionic strength dilute solutions'. Trends in Colloid and Interface Science Xiii, 112 :71-7571. [Details]
Morrissey, S.,Kudryashov, E.,Dawson, K.,Buckin, V.; (1999) 'Surfactant aggregates on the DNA surface'. Biophysical Journal, 76 (11). [Details]
Buckin, V.,,Smyth, C.; (1999) 'High-resolution ultrasonic resonator measurements for analysis of liquids'. Sem Food Anal, 4 (22):113-130113. [Details]
Buckin, V. A. and Smyth, C.,; (1999) 'Precision ultrasonic resonator measurements for analysis of liquids'. SEMINAR IN FOOD ANALYSIS, . [Details]
Morrissey, S; Kudryashov, E; Dawson, K; Buckin, V; ; (1999) 'Surfactant aggregates on the DNA surface'. Biophysical Journal, 76 (1):321-321. [Details]
Kudryashov, E; Kapustina, T; Morrissey, S; Buckin, V; Dawson, K; ; (1998) 'The compressibility of alkyltrimethylammonium bromide micelles'. Journal of Colloid and Interface Science, 203 (1):59-68. [Details]
Kudryashov, E. D.,Braginskaya, F. I.,Buckin, V. A.,Marky, L. A.; (1998) 'Volume and compressibility effects in intercalation of ethidium bromide and daunomycin to DNA'. Biofizika, 43 (11):40-4540. [Details]
Buckin, V., Kudryashov, E., Morrissey, S., Kapustina, T., Dawson, K.; (1998) 'Do surfactants form micelles on the surface of DNA?'. Progress in Colloid and Polymer Science, 110 :214-219214. [Details]
Kankia, BI; Funck, T; Uedaira, H; Buckin, VA; ; (1997) 'Volume and compressibility effects in the formation of metal-EDTA complexes'. Journal of Solution Chemistry, 26 (9):877-888. [Details]
Kudryashov, E.,Morrissey, S.,Gorelov, A.,Buckin, V.,Dawson, K.; (1997) 'Binding of cationic surfactants to DNA. Compressibility and volume effects'. Biophysical Journal, 72 (22). [Details]
Buckin, V.,Tran, H.,Morozov, V.,Marky, L. A.; (1996) 'Hydration effects accompanying the substitution of counterions in the ionic atmosphere of poly(rA)center dot poly(rU) and poly(rA)center dot 2poly(rU) helices'. Journal of the American Chemical Society, 118 (3030):7033-70397033. [Details]
Buckin, V.,Kankiya, B. I.,Morozov, V.,Marky, L. A.; (1996) 'What are the main factors determining the structure of the ionic atmosphere of nucleic'. Biophysical Journal, 70 (22). [Details]
Buckin, V.,Kankiya, B.,Marky, L.; (1996) 'Hydration effects in the ionic atmosphere of nucleic acids'. Progress in Biophysics & Molecular Biology, 65 . [Details]
Hianik, T.,Buckin, V. A.,Piknova, B.; (1994) 'CAN A SINGLE BACTERIORHODOPSIN MOLECULE-CHANGE THE STRUCTURAL STATE OF ONE LIPOSOME'. General Physiology and Biophysics, 13 (66):493-501493. [Details]
Buckin, V. A.,Kankiya, B. I.,Rentzeperis, D.,Marky, L. A.; (1994) 'MG2+ RECOGNIZES THE SEQUENCE OF DNA THROUGH ITS HYDRATION SHELL'. Journal of the American Chemical Society, 116 (2121):9423-94299423. [Details]
Buckin, V. A.,Demaeyer, L.,Funck, T.,Kudrjashov, E.,Braginskaya, F.,Marky, L. A.; (1993) 'APPLICATION OF MODERN ULTRASONIC VELOCITY-MEASUREMENTS FOR THE DIRECT INVESTIGATION OF THE HYDRATION CHANGES IN DNA-LIGAND INTERACTIONS'. Biophysical Journal, 64 (22). [Details]
Buckin, V. A.,De Maeyer, L.,Funck, T.,Kudryashov, E.,Braginskaya, F.,Kankia, B.I.,Marky, L. A.; (1993) 'APPLICATION OF ULTRASONIC VELOCITY TECHNIQUE FOR DIRECT MEASUREMENTS OF THE HYDRATION CHANGES THAT RESULTS FROM THE INTERACTION OF LIGAND WITHOUT DNA'. J. Biol. Struct. Dynamics, 10 . [Details]
Hianik, T.,Piknova, B.,Buckin, V.,Shestimirov, V.,Shnyrov, V.; (1993) 'Thermodynamics and volume compressibility of phosphatidylcholine liposomes containing bacteriorhodopsin'. Progress in Colloid and Polymer Science, 93 :150-152150. [Details]
Buckin, V.A., Kankiya, B.I., Bulichov, N.V., Lebedev, A.V., Gukovsky, I. Ya., Chuprina, V.P. Sarvazyan, A.P., Williams, A.R.; (1989) 'Measurement of anomalously high hydration of (dA)(dT) double helices in dilute solution'. NATURE*, . [Details]
Buckin, V. A.,Kankiya, B. I.,Sarvazyan, A. P.,Uedaira, H.; (1989) 'ACOUSTICAL INVESTIGATION OF POLY(DA).POLY(DT), POLY[D(A-T)].POLY[D(A-T)], POLY(A).POLY(U) AND DNA HYDRATION IN DILUTE AQUEOUS-SOLUTIONS'. Nucleic Acids Research, 17 (1111):4189-42034189. [Details]
Buckin, V. A.,Kankiya, B. I.,Kazaryan, R. L.; (1989) 'HYDRATION OF NUCLEOSIDES IN DILUTE AQUEOUS-SOLUTIONS ULTRASONIC VELOCITY AND DENSITY-MEASUREMENTS'. Biophysical Chemistry, 34 (33):211-223211. [Details]
Buckin, V. A.; (1988) 'HYDRATION OF NUCLEIC BASES IN DILUTE AQUEOUS-SOLUTIONS - APPARENT MOLAR ADIABATIC AND ISOTHERMAL COMPRESSIBILITIES, APPARENT MOLAR VOLUMES AND THEIR TEMPERATURE SLOPES AT 25-DEGREES-C'. Biophysical Chemistry, 29 (33):283-292283. [Details]
Buckin, V. A.; (1988) 'ACOUSTICAL INVESTIGATION OF THE HYDRATION OF NUCLEIC BASES IN AQUEOUS-SOLUTIONS - ANOMALIES OF WATER IN THE HYDRATION SHELL'. Biofizika, 33 (66):926-931926. [Details]
Bukin, V. A.; (1987) 'EXPERIMENTAL STUDIES OF DNA-WATER INTERACTION'. Molecular Biology, 21 (33):512-525512. [Details]
Buckin, V. A.,Tselikova, S. V.,Sarvazyan, A. P.; (1982) 'A NEW METHOD OF INVESTIGATION OF COUNTERION-NUCLEIC ACID INTERACTIONS'. Studia Biophysica, 87 (2-32-3):233-234233. [Details]
Buckin, V. A.,Sarvazyan, A. P.,Buckina, S. N.,Abagyan, R. A.; (1982) 'ULTRASONIC INVESTIGATION OF NUCLEIC BASE HYDRATION AND ITS CHANGES AT STACKING ASSOCIATION'. Studia Biophysica, 87 (2-32-3):221-222221. [Details]
Sarvazyan, A. P.,Buckin, V. A.,Hemmes, P.; (1980) 'ULTRASONIC INVESTIGATION OF SOLUTE-SOLVENT AND SOLUTE-SOLUTE INTERACTIONS IN AQUEOUS-SOLUTIONS OF BASES, NUCLEOSIDES, AND NUCLEOTIDES .1. DEPENDENCE OF SOLUTE-SOLVENT INTERACTIONS ON THE CHEMICAL-STRUCTURE OF BASES, NUCLEOSIDES, AND NUCLEOTIDE'. Journal of Physical Chemistry, 84 (77):692-696692. [Details]
Hemmes, P.,Mayevski, A. A.,Buckin, V. A.,Sarvazyan, A. P.; (1980) 'ULTRASONIC INVESTIGATION OF SOLUTE-SOLVENT AND SOLUTE-SOLUTE INTERACTIONS IN AQUEOUS-SOLUTIONS OF BASES, NUCLEOSIDES, AND NUCLEOTIDES .3. SOLUTE-SOLUTE INTERACTIONS - STUDIES OF BASE STACKING BY ULTRASONIC VELOCITY-MEASUREMENTS'. Journal of Physical Chemistry, 84 (77):699-703699. [Details]
Buckin, V. A.,Sarvazyan, A. P.,Dudchenko, E. I.,Hemmes, P.; (1980) 'ULTRASONIC INVESTIGATION OF SOLUTE-SOLVENT AND SOLUTE-SOLUTE INTERACTIONS IN AQUEOUS-SOLUTIONS OF BASES, NUCLEOSIDES, AND NUCLEOTIDES .2. PH-DEPENDENT SOLUTE-SOLVENT INTERACTIONS'. Journal of Physical Chemistry, 84 (77):696-699696. [Details]
Buckin, V. A.,Sarvazyan, A. P.; (1980) 'ULTRASONIC INVESTIGATION OF MOLECULAR-INTERACTIONS AND HYDRATION OF POLYNUCLEOTIDES IN AQUEOUS-SOLUTIONS'. Studia Biophysica, 79 :77-7877. [Details]
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Honours and Awards

Year: 1971.
Title: Fellowship at Advanced Kolmogorov School of Mathematics and Physics (Lomonosov Moscow State University)

Year: 1991.
Title: Alexander von Humboldt Fellowship (distinguisher young academic researches), Germany

Year: 1993.
Title: Academic Max-Planck Fellowship, Max-Planck-Institute for Biophysical Chemistry, Germany

Year: 1999.
Title: Chairman of the 13th Conference of European Colloid and International Society

Year: 2002.
Title: R&D Top 100 Award in Technology for high-resolution ultrasonic spectroscopy (USA, Worlds 100 best industrial and technical innovations)

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Associations

Association: American Biophysical Society, Function/Role: member

Association: American Chemical Society, Function/Role: member

Patents

Patent DE 42 01 157 AI : PC-gesteuert Direct-Digital Synthesizer

Patent DE 43 13 216 : Ultrasonic Measurement Equipment with at least one Non-Piezoelectric Resonator Chamber Body and outer Electroacoustic Transducer

Patent EU 0621965 : PC-Controlled Direct-Digital Synthesiser

Patent USA 5,636,149 : PC- Controlled Direct-Digital Synthesiser and Method of Operating the Same

Patent JP2006-504579 : Ultrasonic Analyser

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Education

Year 1978 Institution: Lomonosov Moscow State University
Qualification: MS Subject: Physics/Biological Physics (first class honour)

Year 1984 Institution: Institute of Biological Physics (Russian Academy of Sciences)
Qualification: PhD Subject: Biological Physics

Year 1972 Institution: Advanced Kolmogorov School of Mathematics and Physics (Lomonosov Moscow State University)
Qualification: Diploma Subject: Mathematics/Physics

Other Activities

Technology transfer: Representative publications of academic research groups utilising HR-US spectrometers:

Monitoring the aggregation behaviour of self-assembling polymers through high-resolution ultrasonic spectroscopy. 2010. Int J Pharmaceutics 388(1-2):274-279. (By Cespi M, Bonacucina G, Mencarelli G, Pucciarelli S, Giorgioni G, Palmieri GF).
Diffusing wave spectroscopy and ultrasonic spectroscopy: advantages of these non invasive techniques in food colloid research illustrated by rennet-induced gelation of skim milk in the presence of pectin.2008. Agro Food Industry Hi-Tech 19(3):54-57. (By Corredig M, Lopez A, Alexander M.)
Determination of reference ultrasound parameters for model and hydrofluoroalkane propellants using high-resolution ultrasonic spectroscopy. 2008. Aaps Pharmscitech 9(2):605-611. (By Hoe S, Young PM, Rogueda P, Traini D).
New insights into aggregation and conformational behaviour of humic substances: Application of high resolution ultrasonic spectroscopy.2007. Org Geochemistry 38(12):2098-2110. (By Kucerik J, Smejkalova D, Cechlovska H, Pekar M.).
Simultaneously measuring concentrations of a model drug and a model excipient in solution using ultrasonic spectrometry. 2005. J Pharm Biomedical Analysis 37(2):239-247. (By Chen RR, Zelesky T, Ilasi N, Sekulic SS.).
High-Q ultrasonic determination of the critical nanoaggregate concentration of asphaltenes and the critical micelle concentration of standard surfactants.2005. Langmuir 21(7):2728-2736. (By Andreatta G, Bostrom N, Mullins OC.)
Ultrasonic wave spectroscopy study of sugar oligomers and polysaccharides in aqueous solutions: The hydration length concept. 2005. International J Biol Macromol 36(5):275-282. (By Aeberhardt K, Saint Laumer JYD, Bouquerand PE, Normand V.)
Use of ultrasound spectroscopy to examine the effect of cysteine on beta-lactoglobulin interactions.2009. Colloid Polym Sci 287(12):1487-1491. (By Yuno-Ohta N.)
2008. Immunoglobulin dynamics, conformational fluctuations, and nonlinear elasticity and their effects on stability. 2010. J Phys Chem B 112(10):3240-3250.(By Kamerzell TJ, Ramsey JD, Middaugh CR.)
A novel real-time ultrasonic method for prion protein detection using plasminogen as a capture molecule. 2007. Bmc Biotechnology 7:7. (By Negredo C, Monks E, Sweeney T.)
LCST demixing in poly(vinyl methyl ether)/water studied by means of a High Resolution Ultrasonic Resonator.2009. J Therm Anal Calorim 98(2):495-505. (By Van Durme K, Van Assche G, Rahier H, Van Mele B.)

Internal Collaborators

External Collaborators

Collaborative projects with industrial partners:

Glanbia (Avonmore/ Waterford Foods, Ireland) -Stability of some product formulations (milk based drinks). As a result of our cooperation the causes of instability were understood and the ways of overcoming them were developed.
AstraZeneca (UK research facility), inhaler drug formulations. Sedimentation of drug micro-particles in inhaling formulations.
Aphton Pharmaceutical, (UK research facility), complex anticancer drug formulations quality control of emulsions. Microemulsion based formulations.
DSM (Netherlands): ultrasonic monitoring of enzyme reactions in complex media.

Invited lectures and seminars at industrial sites on applications of ultrasonic spectroscopy:
GSK ( UK), Avecia (UK), Aventis (UK), Unilever (UK), Syngenta (UK), Pfizer (UK and USA), Schlumberge (US), Firmenich (Switzerland), GE Global Research (USA), Amgen (USA), Avery (USA), Baxter Research (USA), Con Agra (USA), ABC Research (USA), AstraZeneca (UK), Kraft, Germany), Genzyme (UK), Merck Sharp and Dohme (UK), Samyang Research Center (S. Korea), Yahan Corp Research Center (S. Korea), Sun Chemical (USA ), Honeywell (USA), Masterfoods (US), Pepsi (USA), Colgate (USA), Bayer (USA), Genencore (USA), ICI (UK), P&G (UK ), Bio-Rad (USA), Sericol Fujifilm, (UK), BP (Technology Centre, UK), Chemtura (Worcestershire, UK).

Patent 275,437 B2 : Acoustical cell for material Analysis, I
Patent 2003-576950 : Acoustical cell for material Analysis,II
Patent 2002804885.8 : Acoustic Resonator Cell
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Year: 2002. Title: Silver Award for Best New Product (introduction of HR-US 101 spectrometer) at PITTCON ANALYTICAL SHOW 2002 (USA)
Year: 2003. Title: Best UK Research Group Award (United Kingdom Laboratory News magazine)
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