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2012 FEBS Journal Prize for Conway researcher
Dr Rosemarie Carew, pictured right, is the winner of the 2012 FEBS Journal Prize for Young Scientists. The award recognises the best published paper by a young scientist (no more than 3 years from the time of award of the Ph. D degree when the paper is submitted) who is the first author of a paper that is judged to be the best in FEBS Journal during the previous calendar year.
Dr Carew carried out her PhD research in UCD Conway Institute and UCD Diabetes Research Centre under the supervision of Dr. Derek Brazil, who relocated to Queen's University Belfast in 2009. Rosemary graduated in the same year and the findings of her doctoral research were published in FEBS Journal in September 2011.
In this paper, Rosemarie identified for the first time that the pro-fibrotic cytokine transforming factor beta (TGFb1) could regulate key proteins in insulin signalling called IRS-2 and Foxo3a. Using human kidney epithelial cells, she showed that signalling through these proteins was involved in TGFb1-induced regulation of epithelial cell junction proteins such as E-cadherin. Overall, these data expand our knowledge of the complexity of TGFbeta1 signalling in kidney epithelial cell signalling.
Rosemarie, who is now employed by Firecrest Clinical in Limerick, will attend the IUBMB–FEBS Congress in Seville, Spain in September 2012 to receive her award and give a presentation about her work, which was supported by IRCSET's EMBARK Postgraduate Scholarship and SFI.
About Federation of European Biochemical Societies (FEBS)
FEBS is one of the largest organisations in European life sciences, with nearly 40.000 members distributed among 36 Constituent Societies and 7 Associated Member Societies in 43 countries. It seeks to promote, encourage and support biochemistry, molecular cell biology and molecular biophysics throughout Europe.
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