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UCD Conway announced as reference centre for new protein stabilising technology

UCD Conway Proteome Research Centre will become a reference centre for the Denator Stabilizor™ T1 system for stabilising tissue samples from the moment of sampling. UCD Conway researchers will also demonstrate the Stabilizor™ technology to other potential customers and gain early access to new products for stabilisation of biological samples.

Protein and peptide degradation begins when a biological specimen is sampled, potentially causing the distortion or destruction of vital information about the original biological state. This can lead to inter-sample variation and the risk of incorrect data interpretation. Swedish biotechnology company, Denator is using patent-pending technology to halt the degradation process and maintain sample stability. 

Prof. Michael Dunn at the Proteome Research Centre, explained, ‘Degradation begins seconds after sampling, thereby distorting the composition of the in vivo proteome. Denator’s rapid heat inactivation technology ensures complete elimination of enzymatic activity, thereby preserving the intact proteome. This will be an important tool that will help to further our understanding of the molecular basis of biological processes in health and disease.’

Prof. Giuliano Elia, Director of the Proteomics/MS Resource Core Facility added, ‘To gain early access to new products for stabilization of biological samples is naturally of great interest for us and will favour us in our work with different types of samples and applications.’

Olof Sköld, CEO at Denator, concluded: ‘We are very pleased that UCD Conway has decided to implement Stabilizor T1 in their eminent research activities, but above all we’re excited that UCD Conway will become reference centre for the Stabilizor system. Degradation of proteins and peptides during sample preparation is a major bottleneck in proteomic research today.”

Reference Publication
Heat Stabilization of the Tissue Proteome: A New Technology for Improved Proteomics (Svensson, et al., J. Proteome Res., 2009, 8 (2), pp 974–981)