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Summer 2011 issue of Conway Focus

The latest edition of the Conway Focus Issue 14 Summer 2011 newsletter is now available and highlights research and innovation achievements from the past three months including:

New avenue to tackle CJD and Alzheimer's disease
Nature Communications publication by Prof. Dominic Walsh outlining how two antibodies could help block the onset of Alzheimer's disease in the brain.

New prostate cancer biomarkers move closer to clinical use 
HRB-SFI Translational Research award to Prof Bill Watson for the validation of a panel of serum biomarkers to inform surgical intervention for prostate cancer.

Protecting against adipose tissue inflammation in obesity
Diabetes publication by Prof. Helen Roche describes how, in obesity, cells of the immune system (macrophages & T-cells) respond to a high fat diet by entering adipose tissue and releasing proinflammatory cytokines ( IL-1, IL-6, TNF-alpha).

c-Myc impacts alternate splicing of key signalling factors
Proto-oncogenic factor, c-Myc directly affects the alternate splicing machinery of key signalling components in an effort to coordinate cell processes such as growth, proliferation, differentiation and apoptosis - Cancer Research publication led by Prof. Walter Kolch. 

Lipoxins attenuate renal fibrosis
Tackling unresolved inflammation may be a viable therapeutic option in renal fibrosis and chronic renal disease including diabetic nephropathy as described in Faseb Journal by Prof. Catherine Godson.

ISAC Scholar award
Dr Alfonso Blanco has received the 2011 ISAC Scholar award from the International Society for Advancement of Cytometry.

Proteomic changes in schizophrenia & bipolar disorder
The first detailed research study of protein expression changes within the hippocampus in schizophrenia and bipolar disorder  - collaborative research by Prof. David Cotter (RCSI & Beaumont Hospital) with Prof. Michael Dunn.

Pitching to ‘Get Started’
Dr Patricia McGowan was awarded joint first prize from the TIDA / SFI ‘Get Started’ Technology Venture Programme organised by Science Foundation Ireland (SFI) and the Irish Technology Leadership Group (ITLG).

Bright futures ahead for Team SAP Ireland
Dr Patricia Maguire recently hosted a visit to UCD by Team SAP Ireland, a group of six transition year secondary school students and their teacher, Mr Declan Askin from St Gerard’s College, Castlebar.