Dr. Francesca Paradisi

Research

Dr Francesca Paradisi MSc PhD

Peer Reviewed Journals:

Hackenberg, F. et al. (2012) 'Novel non-symmetrically p-benzyl-substituted (benz)imidazole N-heterocyclic carbene-silver(I) acetate complexes ¿ synthesis and biological evaluation'. International Journal of Inorganic Chemistry, 2012 :Article ID 12154-13 pages. [DOI] [Details]

Timpson, L. et al. (2012) 'Characterization of alcohol dehydrogenase (ADH12) from Haloarcula marismortui, an extreme halophile from the Dead Sea'. Extremophiles, 16 :57-66. [DOI] [Details]

Lestini, E. et al. (2012) 'An alternative mild route to the synthesis of 4-methylenecyclohex-2-enone, a key moiety of the anticancer compounds ottelione A and B'. Synthetic Communications, 42 :1864-1876. [DOI] [Details]

Devereux, S. et al. (2011) 'Isolation and Characterisation of Recovered Starch from Industrial Wastewater'. Journal of Polymers and the Environment, 19 (4):971-979. [DOI] [Details]

O'Sullivan, A. et al. (2011) 'Effects of supplementation with vitamin D3 on glucose production pathways in human subjects'. Molecular Nutrition and Food Research, 55 :1018-1025. [DOI] [Details]

Patil, S. et al. (2011) 'Synthesis, Cytotoxicity and Antibacterial Studies of Novel Symmetrically and Non-Symmetrically p-Nitrobenzyl-Substituted N-Heterocyclic Carbene- Silver(I) Acetate Complexes'. Journal of Inorganic and General Chemistry, 637 :386-396. [DOI] [Details]

Pandurangan, K. et al. (2011) 'Design, Synthesis and Structure of Novel para-quinones and their Antibacterial Activity'. Chemical Biology and Drug Design, 78 :787-799. [DOI] [Details]
Patil, S. et al. (2011) 'Novel Benzyl-Substituted N-Heterocyclic Carbene¿Silver Acetate Complexes: Synthesis, Cytotoxicity and Antibacterial Studies'. Metallomics, 3 :74-88. [Details]
O'Reilly, E. and Balducci, D. and Paradisi, F. (2010) 'A stereocontrolled synthesis of deuterium labelled (S)-α-amino acids'. Amino Acids, 39 :849-858. [Details]
O'Reilly, E and Pes, L. and Paradisi, F. (2010) 'From amines to diketopiperazines: a one-pot approach'. Tetrahedron Letters, 51 :1696-1697. [Details]
Frimannsson, D.O. at al. (2010) 'Light Induced Anti-microbial Properties of a Brominated BF2 ¿ Chelated Tetraarylazadipyrromethene Photosensitizer'. Journal of medicinal chemistry, 53 :7337-7343. [Details]
Patil, S. et al. (2010) 'Synthesis, Cytotoxicity and Antibacterial Studies of Novel Symmetrically and Non-Symmetrically 4-(Methoxycarbonyl)benzyl-Substituted N-Heterocyclic Carbene-Silver Acetate Complexes'. Helvetica Chimica Acta, 93 :2347-2364. [Details]
Moran, S. et al. (2010) 'Production of lipopeptides in Bacillus sp. CS93 isolated from Pozol'. FEMS Microbiol Letters, 304 :69-73. [DOI] [Details]
Pandurangan, K. et al. (2010) 'Structure and Anti-Microbial Activity of the Silver(I) Complex of 2-Aminophenoxazine-3-one'. Metallomics, 2 :530-534. [Details]
Patil, S. et al. (2010) 'Synthesis, Cytotoxicity and Antibacterial Studies of Symmetrically and Non-Symmetrically Benzyl- or p- Cyanobenzyl-Substituted N-Heterocyclic Carbene-Silver Complexes'. Applied Organometallic Chemistry, 24 :781-793. [Details]
Patil, S et al. (2010) 'Synthesis, Cytotoxicity and Antibacterial Studies of p-Methoxybenzyl-Substituted and Benzyl-Substituted N-Heterocyclic Carbene-Silver Complexes'. European Journal of Inorganic Chemistry, :1020-1031. [DOI] [Details]
Conway PA, Devine K, Paradisi F (2009) 'A simple and efficient method for the synthesis of Erlenmeyer azlactones'. Tetrahedron, 65 (15):2935-2938. [Details]
O'Reilly E, Lestini E, Baiducci D, et al. (2009) 'One-step diketopiperazine synthesis using phase transfer catalysis'. Tetrahedron Letters, 50 (15):1748-1750. [Details]
Paradisi, F,Conway, PA,Maguire, AR,Engel, PC (2008) 'Engineered dehydrogenase biocatalysts for non-natural amino acids: efficient isolation of the D-enantiomer from racemic mixtures'. Organic and Biomolecular Chemistry, 6 :3611-3615. [DOI] [Details]
Gleeson, B. et al. (2008) '\i Novel organotin antibacterial and anticancer drugs0'. Polyhedron, 27 :3619-3624. [Details]
Giacomini, D. et al. (2007) 'Highly Efficient Asymmetric Reduction of Arylpropionic-aldehydes by Horse Liver Alcohol-Dehydrogenase Through Dynamic Kinetic Resolution'. Chemical Communications, :4038-4040. [Details]
Paradisi, F, Collins, S, Maguire, AR, Engel, PC, (2007) 'Phenylalanine dehydrogenase mutants: Efficient biocatalysts for synthesis of non-natural phenylalanine derivatives'. Journal of Biotechnology, 128 (2):408-411. [DOI] [Details]
Nakazawa, N, Montedonico, S, Takayasu, H, Paradisi, F, Puri, P, (2007) 'Disturbance of retinol transportation causes nitrofen-induced hypoplastic tung'. J Pediatr Surg, 42 :345-349. [Details]
Paradisi, F, Woolfson, R, Geoghegan, KF, Engel, PC, (2005) 'Identification of the residue responsible for catalysing regeneration of activity in the inactive glutamate dehydrogenase mutant D165N'. FEBS Letters, 579 (13):2830-2832. [Details]
Paradisi, F, Dean, JLE, Geoghegan, KF, Engel, PC, (2005) 'Spontaneous chemical reversion of an active site mutation: Deamidation of an asparagine residue replacing the catalytic aspartic acid of glutamate dehydrogenase'. Biochemistry, 44 (9):3636-3643. [DOI] [Details]
Faulkner, E; Barrett, M; Okor, S; Kieran, P; Casey, E; Paradisi, F; Engel, P; Glennon, B; (2006) 'Use of fed-batch cultivation for achieving high cell densities for the pilot-scale production of a recombinant protein (phenylalanine dehydrogenase) in Escherichia coli'. Biotechnology Progress, 22 (3):889-897. [Details]
Cainelli, G; Engel, PC; Galletti, P; Giacomini, D; Gualandi, A; Paradisi, F; (2005) 'Engineered phenylalanine dehydrogenase in organic solvents: homogeneous and biphasic enzymatic reactions'. Organic and Biomolecular Chemistry, 3 (24):4316-4320. [Details]
Batoux, NE; Paradisi, F; Engel, PC; Migaud, ME; (2004) 'Novel nicotinamide adenine dinucleotide analogues as selective inhibitors of NAD+-dependent enzymes'. Tetrahedron, 60 (31):6609-6617. [Details]
Busca, P; Paradisi, F; Moynihan, E; Maguire, AR; Engel, PC; (2004) 'Enantioselective synthesis of non-natural amino acids using phenylalanine dehydrogenases modified by site-directed mutagenesis'. Organic and Biomolecular Chemistry, 2 (18):2684-2691. [Details]
Paradisi F., F. Piccinelli, G. Porzi, S. Sandri (2002) 'Enantioselective Synthesis of 2,6-diaminopimelic acid derivatives. Part 3'. Tetrahedron, 13 :497-502. [Details]
Arcelli, F. Paradisi, G. Porzi, S. Rinaldi, S. Sandri (2002) 'Acid Hydrolysis of the Ether Bond Assisted by the Neighbouring Amide Group: Effects Induced by Salts and by Structural Changes. Part 6'. Journal of Chemical Research-S, 5 :501-518. [Details]
Paradisi F., G. Porzi, S. Sandri (2001) 'A new stereocontrolled synthesis of uncommon tripeptides derived from (2,6)-diaminopimelic acid (2,6-DAP)'. Tetrahedron, 12 :3319-3324. [Details]
Paradisi F., G. Porzi, S. Rinaldi, S. Sandri (2000) 'A simple asymmetric synthesis of (+)- and (-)-2,6-diaminopimelic acids;'. Tetrahedron, 11 :1259-1262. [Details]
Paradisi F., G. Porzi, S. Rinaldi, S. Sandri (2000) 'Stereospecific synthesis of a,a-diaminodicarboxylic acids. Part 2;'. Tetrahedron, 11 :4617-4622. [Details]
Cainelli G., D. Giacomini, P. Galletti, P. Orioli, F. Paradisi (2000) 'Diastereofacial Selectivity of O-protected-a - Hydroxy Aldehydes: Temperature and Solvent effect'. European Journal of Organic Chemistry, :3619-3626. [Details]
Di Felice P., M. Maestri, F. Paradisi, G. Porzi, S. Sandri (1999) 'Highly stereocontrolled boron-mediated synthesis of b-hydroxy-a-aminoacids and dipeptides. Part 2;'. Tetrahedron, 10 :4709-4714. [Details]
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Book Chapters:

Conway,P. and Paradisi, F. and Engel, P.C. (2010) 'Synthesis of substituted derivatives of L-phenylalanine and of other non-natural L-amino acids using engineered mutants of phenylalanine dehydrogenase' In: John Whittal & Peter W. Sutton (eds). Practical Methods in Biocatalysis and Biotransformations. Oxford: John Wiley. [DOI] [Details]

Engel, P.C and Paradisi, F. (2010) 'Novel enzymes for biotransformation and resolution of alpha-amino acids' In: J.C Vederas (eds). Comprehensive Natural Product 2 Chemistry and Biology. Oxford: Elsevier. [Details]

Other Journals:

Giacomini, D., Galletti, P. and Paradisi, F. (2008) '\i A further step in the environmentally friendly synthesis of Profens0' Innovations in Pharmaceutical Technology . [Details]

Conference Publications:

Faulkner, E., Barrett, M., Okor, S., Paradisi, F., Engel, P. & Glennon, B. (2005) The use of fed batch cultivation for achieving high cell densities for the pilot scale production of a recombinant protein (Phenylalanine dehydrogenase) in Escherichia coli AIChE Annual Meeting Cincinnati, USA, , 30-OCT-05 - 04-NOV-05 [Details]