Dr. Marguerite Clyne

Research

Dr Marguerite Clyne BA (Mod), PhD.

Book Chapters:

O'Toole P and Clyne M (2001) 'Cell envelope' In: H. Mobley, G. Mendz, S. Hazell (eds). Helicobacter pylori: Physiology and Genetics. Washington DC: ASM Press. [Details]

Stephen Carrington, Marguerite Clyne, Colm Reid, Eammon Fitzpatrick and Anthony Corfield (2009) 'Microbial interaction with mucus and mucins' In: Microbial Glycobiology. United Satates of America: Academic Press. [Details]

Peer Reviewed Journals:

Alemka A, Clyne M, Shanahan F, Tompkins T, Corcionivoschi N, Bourke B (2010) 'Probiotic colonization of the adherent mucus layer of HT29MTXE12 cells attenuates Campylobacter jejuni virulence properties'. Infection and immunity, 78 (6):2812-2822. [DOI] [Details]

Backert S and Clyne M (2011) 'Pathogenesis of Helicobacter pylori infection'. Helicobacter, 16 (Supplement 1):19-25. [Details]

Backert S, Clyne M, Tegtmeyer N (2011) 'Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori'. Cell, 9 (1). [DOI] [Details]

Corcionivoschi N, Clyne M, Lyons A, Elmi A, Gundogdu O, Wren BW, Dorrell N, Karlyshev AV, Bourke B. (2009) 'Campylobacter jejuni cocultured with epithelial cells reduces surface capsular polysaccharide expression'. Infection and Immunity, 77 (5):1959-1967. [Details]

3. Alemka A, Whelan S, Gough R, Clyne M, Gallagher ME, Carrington SD, Bourke B. (2010) 'Purified chicken intestinal mucin attenuates Campylobacter jejuni pathogenicity in vitro'. Journal of Medical Microbiology, 59 :898-903. [Details]

Reeves, EP,Ali, T,Leonard, P,Hearty, S,O'Kennedy, R,May, FEB,Westley, BR,Josenhans, C,Rust, M,Suerbaum, S,Smith, A,Drumm, B,Clyne, M (2008) 'Helicobacter pylori Lipopolysaccharide Interacts With TFF1 in a pH-Dependent Manner'. Gastroenterology, 135 :2043-2054. [DOI] [Details]

Byrne CM, Clyne M, Bourke B. (2007) 'Campylobacter jejuni adhere to and invade chicken intestinal epithelial cells in vitro'. Microbiology, 153 pt. 2 :561-569. [Details]
Dolan, B., Drumm, B., Clyne, M., (2007) 'The interaction of Helicobacter pylori with a mucous secreting cell line'. Zoonoses and Public Health, 54 :95-95. [Details]
Zintl A., Mulcahy G., De Waal T., De Waele V., Byrne C., Clyne M., Holden N. M. and Fanning S. (2006) 'An Irish perspective on Cryptosporidium (part II)'. IRISH VETERINARY JOURNAL, 59 :495-500. [Details]
Hashim, A., Mulchy, G., Bourke, B., Clyne, M. (2006) 'Interaction of Cryptosporidium hominis and Cryptosporidium parvum with primary human and bovine intestinal cells'. INFECTION AND IMMUNITY, 74 (1):99-107. [Details]
Clyne, M; Drumm, B; (2004) 'Helicobacter pylori infection of human and murine primary gastric cells'. Infection and Immunity, 72 (9):5464-5469. [Details]
Bourke B, Mooney A, Byrne C, Clyne M, Johnson-Henry K, Sherman P, (2003) 'Invasion of human epithelial cells by Campylobacter upsaliensis'. Cellular Microbiology, 5 (11):835-847. [Details]
Mooney, A,Clyne, M,Curran, T,Doherty, D,Kilmartin, B,Bourke, B (2001) 'Campylobacter upsaliensis exerts a cytolethal distending toxin effect on HeLa cells and T lymphocytes'. Microbiology, 147 :735-743. [Details]
Mooney A, Clyne M, Curran T, Doherty D, Kilmartin B, Bourke B. (2001) 'Campylobacter upsaliensis exerts cytolethal distending toxin effect on HeLa cells and T lymphocytes'. Microbiology, (47):735-743. [Details]
O Croinin T, Clyne M, Appelmelk B, Claeys D and Drumm B (2001) 'Presence of Antigastric Autoantibodies in Ferrets Naturally Infected with Helicobacter mustelae'. INFECTION AND IMMUNITY, 69 :2708-2713. [Details]
Clyne, M, OCroinin, T, Drumm, B, (2000) 'Adherence mechanism of Helicobacter pylori and Helicobacter mustelae to primary human and ferret gastric cells'. Gut, 47 (NA):1-1. [Details]
Clyne M, O Croinin T, Suerbaum S, Josenhans C and Drumm B (2000) 'Adherence of Isogenic Flagellum Negative Mutants of Helicobacter pylori and Helicobacter mustelae to Human and Ferret Gastric Epithelial Cells'. INFECTION AND IMMUNITY, 68 :4335-4339. [Details]
Clyne, M; Ocroinin, T; Suerbaum, S; Josenhans, C; Drumm, B; (2000) 'Adherence of isogenic flagellum-negative mutants of Helicobacter pylori and Helicobacter mustelae to human and ferret gastric epithelial cells'. Infection and Immunity, 68 (7):4335-4339. [Details]
Clyne, M; O Croinin, T; Drumm, B; (1999) 'Mimicry of blood group antigen A by Helicobacter mustelae and H-pylori - Reply'. Gastroenterology, 116 (2):505-505. [Details]
Goggin, N; Rowland, N; Imrie, C; Walsh, D; Clyne, M; Drumm, B; (1998) 'Effect of Helicobacter pylori eradication on the natural history of duodenal ulcer disease'. Archives of Disease in Childhood, 79 (6):502-505. [Details]
OCroinin, T; Clyne, M; Drumm, B; (1997) 'Helicobacter mustelae specific antibodies cross react with ferret gastric tissue'. Gastroenterology, 112 (4):1054-1054. [Details]
Clyne, M; Drumm, B; (1997) 'Absence of effect of Lewis a and Lewis B expression on adherence of Helicobacter pylori to human gastric cells'. Gastroenterology, 113 (1):72-80. [Details]
Clyne M., and Drumm B. (1997) 'Absence of effect of Lewis A and Lewis B blood group antigen expression on adherence of Helicobacter pylori to gastric cells'. Gastroenterology, 113 :72-80. [Details]
Clyne, M, Drumm, B, (1996) 'Cell envelope characteristics of Helicobacter pylori: Their role in adherence to mucosal surfaces and virulence'. Fems Immunology and Medical Microbiology, 16 (2):141-155. [Details]
Clyne, M; Drumm, B; (1996) 'The urease enzyme of Helicobacter pylori does not function as an adhesin'. Infection and Immunity, 64 (7):2817-2820. [Details]
GORMALLY, SM; PRAKASH, N; DURNIN, MT; DALY, LE; CLYNE, M; KIERCE, BM; DRUMM, B; (1995) 'ASSOCIATION OF SYMPTOMS WITH HELICOBACTER-PYLORI INFECTION IN CHILDREN'. Pediatrics, 126 (5):753-756. [Details]
CLYNE, M; LABIGNE, A; DRUMM, B; (1995) 'HELICOBACTER-PYLORI REQUIRES AN ACIDIC ENVIRONMENT TO SURVIVE IN THE PRESENCE OF UREA'. Infection and Immunity, 63 (5):1669-1673. [Details]
CLYNE, M, DRUMM, B, (1993) 'ADHERENCE OF HELICOBACTER-PYLORI TO PRIMARY HUMAN GASTROINTESTINAL CELLS'. Infection and Immunity, 61 (10):4051-4057. [Details]
LAMBERT, I, CLYNE, M, DRUMM, B, (1993) 'HELICOBACTER-PYLORI IN DENTAL PLAQUES'. Lancet, 341 (8850):957-957. [Details]
CLYNE, M, DRUMM, B, (1993) 'ADHERENCE OF HELICOBACTER-PYLORI TO PRIMARY HUMAN GASTROINTESTINAL CELLS'. Gastroenterology, 104 (4):56-56. [Details]
Clyne M, Dolan B, Reeves EP. (2007) 'Bacterial factors that mediate colonization of the stomach and virulence of Helicobacter pylori'. Fems Microbiology Letters, 268 (2):135-143. [Details]
Hynes SO, Ferris JA, Szponar B, Wadstrom T, Fox JG, O'Rourke J, Larsson L, Yaquian E, Ljungh A, Clyne M, Andersen LP, Moran AP: (2004) 'Comparative chemical and biological characterization of the lipopolysaccharides of gastric and enterohepatic helicobacters'. Helicobacter, (9):313-323. [Details]
Hashim, A; Clyne, M; Mulcahy, G; Akiyoshi, D; Chalmers, R; Bourke, B; (2004) 'Host cell tropism underlies species restriction of human and bovine Cryptosporidium parvum genotypes'. Infection and Immunity, 72 (10):6125-6131. [Details]
Clyne M, Dillon P, Daly S, O'Kennedy R, May FE, Westley BR, Drumm B. (2004) 'Helicobacter pylori interacts with the human single-domain trefoil protein TFF1'. Proceedings of the National Academy of Sciences of the, 101 (19):7409-7414. [Details]
Mooney, A; Clyne, M; Curran, T; Doherty, D; Kilmartin, B; Bourke, B; (2001) 'Campylobacter upsaliensis exerts a cytolethal distending toxin effect on HeLa cells and T lymphocytes'. Microbiology-Uk, 147 (NA):735-743. [Details]
Clyne M, Ocroinin T, Suerbaum S, Josenhans C, Drumm B. (2000) 'Adherence of isogenic flagellum-negative mutants of Helicobacter pylori and Helicobacter mustelae to human and ferret gastric epithelial cells'. Infection and Immunity, 68 (7). [Details]
Goggin, N; Rowland, N; Imrie, C; Walsh, D; Clyne, M; Drumm, B; (1998) 'Effect of Helicobacter pylori eradication on the natural history of duodenal ulcer disease'. Archives of Disease in Childhood, 79 (6):502-505. [Details]
Croinin, TO; Clyne, M; Drumm, B; (1998) 'Molecular mimicry of ferret gastric epithelial blood group antigen a by Helicobacter mustelae'. Gastroenterology, 114 (4):690-696. [Details]
Clyne M, Thomas J, Weaver L, Drumm B. (1997) 'In vitro evaluation of the role of antibodies against Helicobacter pylori in inhibiting adherence of the organism to gastric cells'. Gut, 40 (6):731-738. [Details]
Clyne M, Drumm B. (1993) 'Adherence of Helicobacter pylori to primary human gastrointestinal cells'. Infection and Immunity, 61 (10):4051-4057. [Details]
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Conference Publications:

Gallagher HC, Clyne M, Shields DC and O'Connor C (2009) Thematic PhD programmes at the UCD School of Medicine and Medical Science, Dublin, Ireland Orpheus Conference on PhD Education in Europe [Details]

McNally, S., Clyne, M., Carrington, S.D. and Reid C (2007) The generation of a recombinant MUC2 clone to investigate the interaction of Campylobacter jejuni and intestinal mucus Mucins in Health and Disease (9th International Workshop on Carcinoma-associated Mucins) Robinson College Cambridge July 2007 [Details]

Smith, A., Clyne, M., Carrington, S.D., Drumm, B., and Reid, C. (2007) Construction and expression of a truncated version of MUC5AC as a model system to investigate its role in pathogen'mucosal interactions Mucins in Health and Disease (9th International Workshop on Carcinoma-associated Mucins) Robinson College Cambridge July 2007 [Details]

O Croinin T, Clyne M, Appelmelk B, Claeys D and Drumm B (1999) Presence of anti-gastric atuoantibodies in ferrets naturally infected with Helicobacter mustelae American Society of Microbiology : Annual General Meeting [Details]

Clyne M, O Croinin T and Drumm B (1999) Adherence of Helicobacter pylori and Helicobacter mustelae to gastric cells studied using confocal microscopy American Society of Microbiology : Annual General Meeting [Details]

O Croinin T, Clyne M and Drumm B (1997) Molecular mimicry of ferret gastric epithelial blood group antigen A by Helicobacter mustelae American Gastroenterology Association : Annual General Meeting [Details]

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