Dr. Matthias Tacke | UCD Conway

Research

Dr Matthias Tacke PhD

Book Chapters:

M. Hogan, M. Tacke (2010) 'Titanocenes - Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer' In: G. Jaouen, N. Metzler-Nolte (eds). Topics in Organometallic Chemistry, Volume 32: Medicinal Organometallic Chemistry. Heidelberg: Springer. [Details]

Peer Reviewed Journals:

L. Kaps, B. Biersack, H. Müller-Bunz, K. Mahal, J. Münzner, M. Tacke, T. Mueller, R. Schobert (2012) 'Gold(I)-NHC complexes of antitumoral diarylimidazoles: structures, cellular uptake routes and anticancer activities'. Journal of Inorganic Biochemistry, 106 (1):52-58. [Details]

L. Kater, J. Claffey, M. Hogan, P. Jesse, B. Kater, S. Strauß, M. Tacke, A. Prokop (2012) 'Titanocene Y induces apoptosis via the extrinsic FAS pathway and overcomes multiple drug resistance in malignant leukemia cells'. Toxicology in Vitro, 26 (2):119-124. [Details]

R. Hilger, D. Alex, A. Deally, B. Gleeson, M. Tacke (2011) 'Titanocene Y and Vanadocene Y: Platinum Resistance-Breaking Cytotoxic and DNA-Targeting Anticancer Drug Candidates'. Letters in Drug Design & Discovery, 8 (10):904-910. [Details]

S. Patil, M. Tacke (2011) 'NHC-Silver(I) Acetates as Bioorganometallic Anticancer and Antibacterial Drugs'. Insights into Coordination, Bioinorganic and Applied Inorganic Chemistry, :555-566. [Details]

S. Patil, A. Deally, F. Hackenberg, L. Kaps, H. Müller-Bunz, R. Schobert, M. Tacke (2011) 'Novel Benzyl- or 4-Cyanobenzyl-Substituted N-Heterocyclic (Bromo)(carbene)silver(I) and (Carbene)(chloro)gold(I) Complexes: Synthesis and Preliminary Cytotoxicity Studies'. Helvetica Chimica Acta, 94 :1551-1562. [Details]

J. Zagerman, A. Deally, N. Metzler-Nolte, H. Müller-Bunz, D. Wallis, M. Tacke (2011) 'Towards Protein-Substituted Titanocene Anticancer Drugs'. Polyhedron, 30 :2387-2390. [Details]

I. Fichtner, D. Behrens, J. Claffey, A. Deally, S. Patil, H. Weber, M. Tacke (2011) 'The Antiangiogenic and Antitumoral Activity of Titanocene Y* in vivo'. Letters in Drug Design & Discovery, 8 (4):302-307. [Details]
S. Patil, A. Deally, B. Gleeson, H. Müller-Bunz, F. Paradisi, M. Tacke (2011) 'Novel Benzyl-Substituted N-Heterocyclic Carbene¿Silver Acetate Complexes: Synthesis, Cytotoxicity and Antibacterial Studies'. Metallomics, 3 :74-88. [Details]
S. Cuffe, C. M. Dowling, J. Claffey, C. Pampillón, M. Hogan, J. M. Fitzpatrick, M. P. Carty, M. Tacke, R. W. G. Watson (2011) 'Effects of Titanocene Dichloride Derivatives on Prostate Cancer Cells, Specifically DNA Damage Induced Apoptosis'. Prostate, 71 :111-124. [Details]
A. Deally, B. Gleeson, H. Müller-Bunz, S. Patil, D. F. O¿Shea, M. Tacke (2011) 'Novel Achiral Indole-Functionalised Titanocenes: Synthesis and Preliminary Cytotoxicity Studies'. Journal of Organometallic Chemistry, 696 :1072-1083. [Details]
S. Patil, A. Deally, B. Gleeson, F. Hackenberg, H. Müller-Bunz, F. Paradisi, M. Tacke (2011) 'Synthesis, Cytotoxicity and Antibacterial Studies of Novel Symmetrically and Non-Symmetrically p-Nitrobenzyl-Substituted N-Heterocyclic Carbene-Silver(I) Acetate Complexes'. ZAAC, 637 :386-396. [Details]
L. M. Menéndez Méndez, A. Deally, D. F. O'Shea, M. Tacke (2011) 'Synthesis and Cytotoxicity Studies of Azaindole-Substituted Titanocenes'. Heterotam Chemistry, 22 (2):148-157. [Details]
U. Olszewski, J. Claffey, M. Hogan, M. Tacke, R. Zeillinger, P. Bednarski, G. Hamilton (2011) 'Anticancer activity and mode of action of titanocene C'. Investigational New Drugs, 29 :607-614. [Details]
J. Claffey, H. Müller-Bunz, M. Tacke (2010) 'Benzyl-Substituted Titanocene Dichloride Anticancer Drugs: From Lead to Hit'. Journal of Organometallic Chemistry, 695 :2105-2117. [Details]
J. Claffey, A. Deally, B. Gleeson, S. Patil, M. Tacke (2010) 'Synthesis and Cytotoxicity Studies of Novel Anion-Exchanged Titanocene Y Derivatives'. Applied Organometallic Chemistry, 24 :675-679. [Details]
S. Patil, K. Dietrich, A. Deally, B. Gleeson, H. Müller-Bunz, F. Paradisi, M. Tacke (2010) 'Synthesis, Cytotoxicity and Antibacterial Studies of Novel Symmetrically and Non-Symmetrically Methyl Benzoate-Substituted N-Heterocyclic Carbene-Silver Acetate Complexes'. Helvetica Chimica Acta, 93 :2347-2364. [Details]
B. Gleeson, S. Patil, A. Deally, H. Müller-Bunz, M. Tacke (2010) 'Novel Achiral Aryl-Substituted Vanadocenes: Synthesis and Preliminary Cytotoxicity Studies'. Australian Journal of Chemistry, 63 :1514-1520. [Details]
B. Gleeson, M. Hogan, H. Müller-Bunz, M. Tacke (2010) 'Synthesis and Preliminary Cytotoxicity Studies of Indole-Substituted Vanadocenes'. Transition Metal Chemistry, 35 :973-983. [Details]
M. Hogan, M. Tacke (2010) 'Titanocenes - Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer'. Topics in Organometallic Chemistry: Medicinal Organometallic Chemistry, 32 :119-140. [Details]
S. Patil, A. Deally, B. Gleeson, H. Müller-Bunz, F. Paradisi, M. Tacke (2010) 'Synthesis, Cytotoxicity and Antibacterial Studies of Symmetrically and Non-Symmetrically Benzyl- or p-Cyanobenzyl-Substituted N-Heterocyclic Carbene-Silver Complexes'. Applied Organometallic Chemistry, 24 :781-793. [Details]
A. Deally, J. Claffey, B. Gleeson, M. Hogan, H. Müller-Bunz, S. Patil, D. O'Shea, M. Tacke (2010) 'Synthesis and Preliminary Cytotoxicity Studies of Achiral Pyrrolyl-Substituted Titanocenes'. Polyhedron, 29 (12):2445-2453. [Details]
J. Claffey, A. Deally, B. Gleeson, M. Hogan, L. M. Menéndez Méndez, H. Müller-Bunz, D. Wallis, S. Patil, M. Tacke (2009) 'Pseudo-Halide Derivatives of Titanocene Y: Synthesis and Cytotoxicity Studies'. Metallomics, 1 :511-517. [Details]
Sweeney, N,Gallagher, WM,Muller-Bunz, H,Pampillon, C,Strohfeldt, K,Tacke, M (2006) 'Heteroaryl substituted titanocenes as potential anti-cancer drugs'. Journal of Inorganic Biochemistry, 100 (NA):1479-1486. [DOI] [Details]
Sweeney, N,Gallagher, WM,Muller-Bunz, H,Pampillon, C,Strohfeldt, K,Tacke, M (2006) 'Heteroaryl substituted titanocenes as potential anti-cancer drugs'. Journal of Inorganic Biochemistry, 100 (NA):1479-1486. [DOI] [Details]
Tacke, M,Cuffe, LP,Gallagher, WM,Lou, Y,Mendoza, O,Muller-Bunz, H,Rehmann, FJK,Sweeney, N (2004) 'Methoxy-phenyl substituted ansa-titanocenes as potential anti-cancer drugs derived from fulvenes and titanium dichloride'. Journal of Inorganic Biochemistry, 98 (NA):1987-1994. [DOI] [Details]
Tacke, M,Cuffe, LP,Gallagher, WM,Lou, Y,Mendoza, O,Muller-Bunz, H,Rehmann, FJK,Sweeney, N (2004) 'Methoxy-phenyl substituted ansa-titanocenes as potential anti-cancer drugs derived from fulvenes and titanium dichloride'. Journal of Inorganic Biochemistry, 98 (NA):1987-1994. [DOI] [Details]
Mendoza, O,Rehmann, FJK,Cuffe, LP,Tacke, M (2004) 'Cocondensation reactions of five-membered heterocycles with lithium atoms at 77 K'. Inorganic Chemistry, -1 (22):4525-4532. [DOI] [Details]
Dunne, JP,Tacke, M,Selinka, C,Stalke, D (2003) 'Arylcalcium hydrides as precursors to alkoxides and aryloxides of calcium'. Inorganic Chemistry, -1 (7):1416-1425. [Details]
Dunne, JP,Bockmeyer, M,Tacke, M (2003) 'Co-condensation reactions of substituted aromatic compounds with lithium atoms at 77 K'. Inorganic Chemistry, -1 (3):458-466. [Details]
Fox, S,Dunne, JP,Tacke, M,Schmitz, D,Dronskowski, R (2002) 'Synthesis and structural characterisation of a novel chiral ansa-cobaltocenium hexafluorophosphate'. Inorganic Chemistry, -1 (11):3039-3046. [Details]
S. Patil, J. Claffey, A. Deally, B. Gleeson, M. Hogan, L. M. Menéndez Méndez, H. Müller-Bunz, F. Paradisi, M. Tacke (2010) 'Synthesis, Cytotoxicity and Antibacterial Studies of p-Methoxybenzyl-Substituted and Benzyl-Substituted N-Heterocyclic Carbene-Silver Complexes'. European Journal of Inorganic Chemistry, :1020-1031. [Details]
M. Hogan, B. Gleeson, M. Tacke (2010) 'Synthesis and Preliminary Cytotoxicity Studies of Achiral Indolyl-Substituted Titanocenes'. Organometallics, 29 :1032-1040. [Details]
I. Fichtner, D. Behrens, J. Claffey, A. Deally, B. Gleeson, M. Hogan, H. Weber, M. Tacke (2010) 'Antitumor Activity of Vanadocene Y and its Selenocyanate Derivative in Xenografted CAKI-1 Tumors in Mice'. Journal of Organometallic Chemistry, 695 :1175-1181. [Details]
B. Gleeson, J. Claffey, M. Hogan, H. Müller-Bunz, D. Wallis, M. Tacke (2010) 'Novel Benzyl-Substituted Molybdocene Anticancer Drugs'. Inorganica Chimica Acta, 363 :1831-1836. [Details]
M. Hogan, B. Gleeson, M. Tacke (2010) 'The Cytotoxicity of Titanocene Y against CAKI-1 Cells: An In Vitro Formulation Study'. Letters in Drug Design & Discovery, 7 (5):310-317. [Details]
A. Erxleben, J. Claffey, M. Tacke (2010) 'Binding and hydrolysis studies of antitumoural titanocene dichloride and Titanocene Y with phosphate diesters'. Journal of Inorganic Biochemistry, 104 :390-396. [Details]
S. Eger, T. A. Immel, J. Claffey, H. Müller-Bunz, M. Tacke, U. Groth, T. Huhn (2010) 'Titanocene difluorides with improved cytotoxic activity'. Inorganic Chemistry, 49 :1292-1294. [Details]
D. Wallis, J. Claffey, B. Gleeson, M. Hogan, H. Müller-Bunz, M. Tacke (2009) 'Novel Zirconocene Anticancer Drugs?'. Journal of Organometallic Chemistry, 694 :828-833. [Details]
A. Vessières, M.-A. Plamont, C. Cabestaing, J. Claffey, S. Dieckmann, M. Hogan, H. Müller-Bunz, K. Strohfeldt, M. Tacke (2009) 'Proliferative and Antiproliferative Effects of Titanium- and Iron-Based Metallocene Anticancer Drugs'. Journal of Organometallic Chemistry, 694 :874-879. [Details]
B. Gleeson, J. Claffey, M. Hogan, H. Müller-Bunz, D. Wallis, M. Tacke (2009) 'Novel Benzyl-Substituted Vanadocene Anticancer Drugs'. Journal of Organometallic Chemistry, 694 :1369-1374. [Details]
B. Gleeson, J. Claffey, A. Deally, M. Hogan, L. M. Menéndez Méndez, H. Müller-Bunz, S. Patil, D. Wallis, M. Tacke (2009) 'Synthesis and Cytotoxicity Studies of Fluorinated Derivatives of Vanadocene Y'. European Journal of Inorganic Chemistry, :2804-2810. [Details]
M. Hogan, M. Tacke (2009) 'Bioorganometallic Chemistry: A Key To New Chemotherapy?'. Insights into Coordination, Bioinorganic and Applied Inorganic Chemistry, :403-412. [Details]
J. Claffey, B. Gleeson, M. Hogan, H. Müller-Bunz, D. Wallis, M. Tacke (2008) '\i Fluorinated Derivatives of Titanocene Y: Synthesis and Cytotoxicity Studies0'. European Journal of Inorganic Chemistry, :4074-4082. [Details]
M. Hogan, J. Cotter, J. Claffey, B. Gleeson, D. Wallis, D. O¿Shea, M. Tacke (2008) '\i Synthesis and Cytotoxicity Studies of New Dimethylamino-Functionalised and Azaindole-Substituted Titanocene Anticancer Agents0'. Helvetica Chimica Acta, 91 :1787-1797. [Details]
I. Fichtner, J. Claffey, B. Gleeson, M. Hogan, D. Wallis, H. Weber, M. Tacke (2008) '\i Antitumor Activity of Oxali-Titanocene Y in Xenografted Caki-1 Tumors in Mice0'. Letters in Drug Design & Discovery, 5 :489-493. [Details]
M. Tacke (2008) 'The Interaction of Titanocene Y with Double-Stranded DNA: A Computational Study'. Letters in Drug Design & Discovery, 5 :332-335. [Details]
Hogan, M., Claffey, J., Pampillon, C., Tacke, M., (2008) 'Synthesis and cytotoxicity studies of new morpholino-functionalised and N-heteroaryl-substituted titanocene anticancer drugs'. Medicinal Chemistry, 4 (2):91-99. [Details]
Dowling, C. M., Claffey, J., Cuffe, S., Fichtner, I., Pampillon, C., Sweeney, N. J., Strohfeldt, K., Watson, R. W. G., Tacke, M., (2008) 'Antitumor activity of Titanocene Y in xenografted PC3 tumors in mice'. Letters in Drug Design & Discovery, 5 (2):141-144. [Details]
Pampillon, C., Claffey, J., Strohfeldt, K., Tacke, M., (2008) 'Synthesis and cytotoxicity studies of new dimethylamino-functionalised and aryl-substituted titanocene anti-cancer agents'. European Journal of Medicinal Chemistry, 43 (1):122-128. [Details]
M. Tacke (2008) 'The Interaction of Titanocene Y with Double-Stranded DNA: A Computational Study'. Letters in Drug Design & Discovery, 5 :332-335. [Details]
B. Gleeson, J. Claffey, D. Ertler, M. Hogan, H. Müller-Bunz, F. Paradisi, D. Wallis, M. Tacke (2008) 'Novel Organotin Antibacterial and Anticancer'. Polyhedron, 27 :3619-3624. [Details]
Weber, H., Claffey, J., Hogan, M., Pampillon, C., Tacke, M., (2008) 'Analyses of Titanocenes in the spheroid-based cellular angiogenesis assay'. Toxicology in Vitro, 22 (2):531-534. [Details]
Pampillon, C., Claffey, J., Hogan, M., Tacke, M., (2008) 'Novel achiral titanocene anti-cancer drugs synthesised from bis-N,N-dimethylamino fulvene and lithiated heterocyclic compounds'. Biometals, 21 (2):197-204. [Details]
Strohfeldt, K., Tacke, M., (2008) 'Bioorganometallic fulvene-derived titanocene anti-cancer drugs'. Chemical Society Reviews, 37 (6):1174-1187. [Details]
Claffey, J., Hogan, M., Muller-Bunz, H., Pampillon, C., Tacke, M., (2008) 'Synthesis and cytotoxicity studies of methoxy benzyl substituted titanocenes'. Journal of Organometallic Chemistry, 693 (3):526-536. [Details]
M. Hogan, J. Claffey, E. Fitzpatrick, T. Hickey, C. Pampillon, M. Tacke (2008) 'Synthesis and Cytotoxicity Studies of Titanocene C Analogues'. Metal-Based Drugs, . [DOI] [Details]
J. Claffey, M. Hogan, H. Müller-Bunz, C. Pampillón, M. Tacke (2008) 'Oxali-Titanocene Y: A Potent Anticancer Drug'. Chemmedchem, 3 :729-731. [Details]
Pampillón, C., Claffey, J., Hogan, M., Strohfeldt, K., Tacke, M. (2007) 'Synthesis and Cytotoxicity Studies of New Dimethylamino-Functionalised and Indolyl-Substituted Titanocene Anti-Cancer Drugs'. Transition Metal Chemistry, 32 (4):434-441. [Details]
Oberschmidt, O., Hanauske, A.-R., Pampillón, C., Strohfeldt, K., Sweeney,N. J., Tacke, M. (2007) 'Activity of Titanocene Y against Tumor Colony Forming Units'. Anti-Cancer Drugs, 18 (3):317-321. [Details]
Beckhove, P., Hanauske, A.-R., Oberschmidt, O., Pampillón, C., Schirrmacher, V., Sweeney, N. J., Strohfeldt, K., Tacke, M. (2007) 'Antitumor Activity of Titanocene Y in Freshly Explanted Human Breast Tumors and in Xenografted MCF-7 Tumors in Mice'. Anti-Cancer Drugs, 18 (3):311-315. [Details]
Müller-Bunz, H., Dix, I., Lou, Y., Pampillón, C., Strohfeldt, K., Sweeney, N. J., Tacke, M. (2007) 'A series of novel 6-aryl fulvenes: Impact of substitution on the phenyl ring, characterised by X-Ray crystallography'. Zeitschrift Fur Krystallographie, 222 (7):376-882. [Details]
T. Hickey, J. Claffey, E. Fitzpatrick, M. Hogan, C. Pampillón, M. Tacke (2007) 'Dimethylamino-Functionalised and N-Heteroaryl-Substituted Titanocene Anticancer Drugs: Synthesis and Cytotoxicity Studies'. Investigational New Drugs, 25 (5):425-433. [Details]
Sweeney, NJ; Claffey, J; Muller-Bunz, H; Pampillon, C; Strohfeldt, K; Tacke, M; (2007) 'The synthesis and cytotoxic evaluation of a series of benzodioxole substituted titanocenes'. Appl Organomet Chem, 21 :57-65. [Details]
Hickey, T, Claffey, J, Fitzpatrick, E, Hogan, M, Pampillon, C, Tacke, M, (2007) 'Dimethylamino-functionalised and N-heteroaryl-substituted titanocene anticancer drugs: synthesis and cytotoxicity studies'. INVEST NEW DRUG, 25 :425-433. [Details]
Pampillon, C, Claffey, J, Hogan, M, Strohfeldt, K, Tacke, M, (2007) 'Synthesis and cytotoxicity studies of new dimethylamino-functionalised and indolyl-substituted titanocene anti-cancer drugs'. TRANSIT METAL CHEM, 32 :434-441. [Details]
Hogan, M, Claffey, J, Pampillon, C, Watson, RWG, Tacke, M, (2007) 'Synthesis and cytotoxicity studies of new dimethylamino-functionalized and azole-substituted titanocene anticancer drugs'. Organometallics, 26 :2501-2506. [Details]
Pampillon, C, Claffey, J, Hogan, M, Tacke, M, (2007) 'Morpholino-functionalized and heteroaryl-substituted titanocene anti-cancer drugs: Synthesis and Cytotoxicity studies'. Z ANORG ALLG CHEM, 633 :1695-1700. [Details]
Beckhove, P, Oberschmidt, O, Hanauske, AR, Pampillon, C, Schirrmacher, V, Sweeney, NJ, Strohfeldt, K, Tacke, M, (2007) 'Antitumor activity of Titanocene Y against freshly explanted human breast tumor cells and in xenografted MCF-7 tumors in mice'. ANTI-CANCER DRUG, 18 :311-315. [Details]
Pampillon, C, Sweeney, NJ, Strohfeldt, K, Tacke, M, (2007) 'Synthesis and cytotoxicity studies of new dimethylamino-functionalised and hetero aryl-substituted titanocene anti-cancer drugs'. J ORGANOMET CHEM, 692 :2153-2159. [Details]
Muller-Bunz, H, Dix, I, Strohfeldt, K, Lou, Y, Pampillon, C, Sweeney, NJ, Claffey, J, Tacke, M, (2007) 'Structures of 6-(substituted-phenyl)fulvenes'. Z KRISTALLOGR, 222 :376-382. [Details]
Oberschmidt, O, Hanauske, AR, Pampillon, C, Sweeney, NJ, Strohfeldt, K, Tacke, M, (2007) 'Antiproliferative activity of Titanocene Y against tumor colony-forming units'. ANTI-CANCER DRUG, 18 :317-321. [Details]
Strohfeldt, K., Müller-Bunz, H., Pampillón, C., Tacke, M. (2007) 'Proliferative and Antiproliferative Effects in Substituted Titanocene Anticancer Drugs'. Transition Metal Chemistry, 32 (7):971-980. [Details]
Pampillón, C., Claffey, J., Hogan, M., Tacke, M. (2007) 'Morpholino-Functionalised and Heteroaryl-Substituted Titanocene Anticancer Drugs: Synthesis and Cytotoxicity Studies'. Zeitschrift fuer Anorganische und Allgemeine Chemie, 633 (10):1695-1700. [Details]
Tacke, M, Leyden, R, Cuffe, LP, (2006) 'Reactions of methyllithium with CO and CNMe: Theoretical study'. International Journal of Quantum Chemistry, 106 (3):692-696. [Details]
Watson RW, O'Connor K, Gill C, Tacke M, Rehmann FJ, Strohfeldt K, Sweeney N, Fitzpatrick JM, (2006) 'Novel titanocene anti-cancer drugs and their effect on apoptosis and the apoptotic pathway in prostate cancer cells'. Apoptosis, 7 (NA):1205-1214. [DOI] [Details]
Tacke, M, Leyden, R, Cuffe, LP, (2004) 'A DFT study of the reactions of tetrameric and hexameric methyllithium with CO and CNMe'. Journal of Molecular Structure-Theochem, 684 (1-3):211-215. [Details]
Tacke, M, Allen, LT, Cuffe, L, Gallagher, WM, Ying, L, Mendoza, O, Muller-Bunz, H, Rehmann, FJK, Sweeney, N, (2004) 'Novel titanocene anti-cancer drugs derived from fulvenes and titanium dichloride'. J ORGANOMET CHEM, 689 (13):2242-2249. [Details]
Tacke, M, Fox, S, Cuffe, L, Duune, JP, Hartl, F, Mahabiersing, T, (2001) 'A study of the reduction of substituted fulvenes using spectro-electrochemistry and ab initio theory'. Journal of Molecular Structure, 559 (1-3):331-339. [Details]
Tacke, M, Dunne, JP, Fox, S, Linti, G, Teuber, R, (2001) 'The synthesis, X-ray and DFT structures of the free ansa-cyclopentadiene ligand C5H5CMe2CMe2C5H5'. Journal of Molecular Structure, 570 (1-3):197-202. [Details]
Tacke, M, Dunne, JP, El-Gamati, Fox, S, Rous, A, Cuffe, LP, (1999) 'Matrix effect found in the reaction of GaCl with HCl: application of the Onsager model to describe interactions between matrices and matrix isolated species'. Journal of Molecular Structure, 477 (1-3):221-224. [Details]
Sweeney, N.J., Claffey, J., Muller-Bunz, H., Pampillon, C., Strohfeldt, K., Tacke, M. (2007) 'The synthesis and cytotoxic evaluation of a series of benzodioxole substituted titanocenes'. APPLIED ORGANOMETALLIC CHEMISTRY, 21 (2):57-65. [Details]
Hogan, M., Claffey, J. Pampillón, C., Watson, R. W. G., Tacke, M. (2007) 'Synthesis and Cytotoxicity Studies of New Dimethylamino-Functionalised and Azole-Substituted Titanocene Anti-Cancer Drugs'. Organometallics, 26 (10):2501-2506. [Details]
Pampillón, C. Sweeney, N. J., Strohfeldt, K., Tacke, M. (2007) 'Synthesis and Cytotoxicity Studies of New Dimethylamino-Functionalised and Heteroaryl-Substituted Titanocene Anti-Cancer Drugs'. Journal of Organometallic Chemistry, 692 (11):2153-2159. [Details]
Valadares, MC; Ramos, AL; Rehmann, FJK; Sweeney, NJ; Strohfeldt, K; Tacke, M; Queiroz, MLS; (2006) 'Antitumour activity of [1,2-di(cyclopentadienyl)-1,2-di(p-N,N-dimethylaminophenyl)-ethanediyl] titanium dichloride in xenografted Ehrlich's ascites tumour'. European Journal of Pharmacology, 534 (1-3):264-270. [Details]
Fichtner, I., Pampillón, C., Sweeney, N. J., Strohfeldt, K, Tacke, M. (2006) 'Antitumor Activity of Titanocene Y in Xenografted Caki-1 Tumors in Mice'. ANTI-CANCER DRUGS, . [Details]
Mendoza, O; Tacke, M; (2006) 'Cocondensation reactions of heterocyclic aromatic compounds with lithium, calcium and magnesium atoms at 77 K'. Journal of Organometallic Chemistry, 691 (6):1110-1116. [Details]
Pampillon, C; Mendoza, O; Sweeney, NJ; Strohfeldt, K; Tacke, M; (2006) 'Diarylmethyl substituted titanocenes: Promising anti-cancer drugs'. Polyhedron, 25 (10):2101-2108. [Details]
Fichtner, I; Pampillon, C; Sweeney, NJ; Strohfeldt, K; Tacke, M; (2006) 'Anti-tumor activity of Titanocene Y in xenografted Caki-1 tumors in mice'. ANTI-CANCER DRUG, 17 (3):333-336. [Details]
O'Connor, K; Gill, C; Tacke, M; Rebmann, FJK; Strohfeldt, K; Sweeney, N; Fitzpatrick, JM; Watson, RWG; (2006) 'Novel titanocene anti-cancer drugs and their effect on apoptosis and the apoptotic pathway in prostate cancer cells'. Apoptosis, 11 (7):1205-1214. [Details]
Pampillon, C; Sweeney, NJ; Strohfeldt, K; Tacke, M; (2006) 'Diheteroarylmethyl substituted titanocenes: A novel class of possible anti-cancer drugs'. Inorganica Chimica Acta, 359 (12):3969-3975. [Details]
Tacke, M., Leyden, R., Cuffe, L. P. (2006) 'The Reactions of Methyllithium with CO and CNMe: A Theoretical Study'. Int. J. Quantum Chem, . [Details]
Cuffe, L; MacElroy, JMD; Tacke, M; Kozachok, M; Mooney, DA; (2006) 'The development of nanoporous membranes for separation of carbon dioxide at high temperatures'. Journal of Membrane Science, 272 (1-2):6-10. [Details]
Sweeney, N., Gallagher, W. M., Müller-Bunz, H., Pampillón, C., Strohfeldt, K., Tacke, M. (2006) 'Novel Heteroaryl Substituted Titanocene Anti-Cancer Drugs'. JOURNAL OF INORGANIC BIOCHEMISTRY, . [Details]
Pampillon, C; Sweeney, NJ; Strohfeldt, K; Tacke, M; (2006) 'Diheteroarylmethyl substituted titanocenes: A novel class of possible anti-cancer drugs'. Inorganica Chimica Acta, 359 (12):3969-3975. [Details]
F.-J. K. Rehmann, L. P. Cuffe, O. Mendoza, D. K. Rai, N. Sweeney, K. Strohfeldt, W. M. Gallagher, M. Tacke (2005) 'Heteroaryl Substituted Ansa-Titanocene Anti-Cancer Drugs Derived from Fulvenes and Titanium Dichloride'. Applied Organometallic Chemistry 19 :293-300. [Details]
Sweeney, NJ; Mendoza, O; Muller-Bunz, H; Pampillon, C; Rehmann, FJK; Strohfeldt, K; Tacke, M; (2005) 'Novel benzyl substituted titanocene anti-cancer drugs'. Journal of Organometallic Chemistry, 690 (21-22):4537-4544. [Details]
Rehmann, FJK; Rous, AJ; Mendoza, O; Sweeney, NJ; Strohfeldt, K; Gallagher, WM; Tacke, M; (2005) 'A trimethoxyphenyl substituted ansa-titanocene: A possible anti-cancer drug'. Polyhedron, 24 (11):1250-1255. [Details]
Mendoza, O; Muller-Bunz, H; Tacke, M; (2005) 'Cocondensation reactions of nitrogen-containing heterocycles with lithium atoms at 77 K'. Journal of Organometallic Chemistry, 690 (14):3357-3365. [Details]
Mendoza, O; Cuffe, LP; Rehmann, FJK; Tacke, M; (2005) 'The cocondensation reaction of lithium atoms and anisole: an experimental and theoretical study of the reaction pathway'. Journal of Organometallic Chemistry, 690 (6):1511-1522. [Details]
Rehmann, FJK; Cuffe, LP; Mendoza, O; Rai, DK; Sweeney, N; Strohfeldt, K; Gallagher, WM; Tacke, M; (2005) 'Heteroaryl substituted ansa-titanocene anti-cancer drugs derived from fulvenes and titanium dichloride'. Applied Organometallic Chemistry, 19 (3):293-300. [Details]
Sweeney, N., Mendoza, O., Müller-Bunz, H., Pampillón, C., Rehmann, F.-J. K., Strohfeldt, K., Tacke, M. (2005) 'Novel Benzyl Substituted Titanocene Anti-Cancer Drugs'. JOURNAL OF ORGANOMETALLIC CHEMISTRY, . [Details]
Kelter, G; Sweeney, NJ; Strohfeldt, K; Fiebig, HH; Tacke, M; (2005) 'In-vitro anti-tumor activity studies of bridged and unbridged benzyl-substituted titanocenes'. ANTI-CANCER DRUG, 16 (10):1091-1098. [Details]
Oberschmidt, O; Hanauske, AR; Rehmann, FJK; Strohfeldt, K; Sweeney, N; Tacke, M; (2005) 'Activity of [1,2-di(cyclopentadienyl)-1,2-di(p-N,N-domethylaminophenyl)-ethanediyl] titanium dichloride against tumor colony-forming units'. ANTI-CANCER DRUG, 16 (10):1071-1073. [Details]
O. Mendoza, L. P. Cuffe, F.-J. K. Rehmann, M. Tacke (2005) 'The Cocondensation Reaction of Lithium Atoms and Anisole: An Experimental and Theoretical Study of the Reaction Pathway'. Journal of Organometallic Chemistry, 690 (6):1511-1522. [Details]
O. Mendoza, H. Müller-Bunz, M. Tacke (2005) 'Cocondensation Reactions of Nitrogen-Containing Heterocycles with Lithium Atoms at 77 K'. Journal of Organometallic Chemistry, 690 (14):3357-3365. [Details]
F.-J. K. Rehmann, A. J. Rous, O. Mendoza, N. J. Sweeney, K. Strohfeldt, W. M. Gallagher, M. Tacke (2005) 'Novel Substituted Ansa-Titanocene Anti-Cancer Drugs'. Polyhedron, 24 (11):1250-1255. [Details]
S. Fox, J.P. Dunne, M. Tacke, J.F. Gallagher (2004) 'Novel derivatives of ansa-titanocenes procured from 6-phenylfulvene: a combined experimental and theoretical study'. Inorganica Chimica Acta, 357 (1):225-234. [Details]
M. Tacke, R. Leyden, L. P. Cuffe (2004) 'A DFT study in the reactions of tetrameric and hexameric methyllithium with CO and CNMe'. Journal of Molecular Structure, 684 (1-3):211-215. [Details]
M. Tacke, O. Mendoza, FJK Rehmann, LP Cuffe (2004) 'Cocondensation Reactions of Five-Membered Heterocycles with Lithium Atoms at 77 K'. European Journal of Inorganic Chemistry, (22):4525-4532. [Details]
M. Tacke, L. P. Cuffe, W. M. Gallagher, Y. Lou, O. Mendoza, H. Müller-Bunz, F.-J. K. Rehmann, N. Sweeney (2004) 'Methoxy-phenyl Substituted Ansa-Titanocenes as Potential Anti-Cancer Drugs Derived from Fulvenes and Titanium Dichloride'. Journal of Inorganic Biochemistry, 98 (12):1987-1994. [Details]
M. Tacke, L. T. Allen, L. P. Cuffe, W. M. Gallagher, Y. Lou, O. Mendoza, H. Müller-Bunz, F.-J. K. Rehmann, N. Sweeney (2004) 'Novel Titanocene Anti-Cancer Drugs Derived from Fulvenes and Titanium Dichloride'. Journal of Organometallic Chemistry, 689 (13):2242-2249. [Details]
Fox, S; Dunne, JP; Tacke, M; Gallagher, JF; (2004) 'Novel derivatives of ansa-titanocenes procured from 6-phenylfulvene: a combined experimental and theoretical study'. Inorganica Chimica Acta, 357 (1):225-234. [Details]
J. P. Dunne, M. Bockmeyer, M. Tacke (2003) 'Cocondensation Reactions of Substituted Aromatic Compounds with Lithium Atoms at 77 K'. European Journal of Inorganic Chemistry, :458-466. [Details]
J. P. Dunne, M. Tacke (2003) 'Aryl Calcium Hydrides as Precursors to Alkoxides and Aryloxides of Calcium'. European Journal of Inorganic Chemistry, :1416-1425. [Details]
S. Fox, J. P. Dunne, R. Dronskowski, D. Schmitz, M. Tacke (2002) 'Synthesis and Structural Characterisation of a Novel Chiral ansa-Cobaltocenium Hexafluorophospate'. European Journal of Inorganic Chemistry, :3039-3046. [Details]
F. Hartl, L. Cuffe, J. P. Dunne, S. Fox, T. Mahabiersing, M. Tacke (2001) 'Reduction of Substituted Fulvenes Studied by Spectro-Electrochemistry and Ab Initio Theory'. Journal of Molecular Structure, 559 :331-339. [Details]
M. Tacke, J. P. Dunne, S. Fox, G. Linti, R. Teuber (2001) 'The Synthesis, X-Ray, and DFT Structure of the free ansa-Cyclopentadiene Ligand C5H5CMe2CMe2C5H5'. Journal of Molecular Structure, 570 :197-202. [Details]
Dunne, JP; Fox, S; Tacke, M; (2001) 'A DFT study on structures of aryl calcium hydride in donor solvents'. Journal of Molecular Structure-Theochem, 543 (NA):157-166. [Details]
J. P. Dunne, S. Fox, M. Tacke (2001) 'A DFT Study on Structures of Aryl Calcium Hydrides in Donor Solvents J. Mol. Structure Theochem'. 543 :157-166. [Details]
M. Tacke, J. P. Dunne, I. El-Gamati, S. Fox, L. Cuffe (1999) 'The Matrix Effect Found in the Reaction of GaCl with HCl: Application of the Onsager Model to Describe Interactions between Matrices and Matrix Isolated Species'. Journal of Molecular Structure, 477 :221-224. [Details]
M. Tacke (1998) 'Carbonyl and Benzene Complexes of Lithium: Transition-Metal-Like Behaviour of Lithium in Organolithium Compounds'. European Journal of Inorganic Chemistry, :537-541. [Details]
M. Tacke, R. Teuber (1997) 'Direct Synthesis of Isopropylcyclopentadienyl M(I) Compounds of Ga, Tl, Mn and Cu via Metal Vapor Cocondensation and their Spectroscopic Characterization'. Journal of Molecular Structure, 408 :507-512. [Details]
R. Teuber, G. Linti, M. Tacke (1997) 'The X-Ray Structure of Fe(fulvene)2: The Missing Link in the Direct Synthesis of ansa- and Cpi-Metallocenes (Cpi = C5H4CHMe2)'. Journal of Organometallic Chemistry, 545-546 :105-110. [Details]
M. Tacke, Ch. Tacke, D. J. Stufkens, A. Oskam, J. M. de Wolf, J. Teuben, G. Luinstra (1997) 'IR Spectroscopic Investigations in Reactions between Unsaturated Titanium Complexes and CO or N2 in Liquid Xenon or Heptane'. Journal of Molecular Structure, 408/409 :499-505. [Details]
M. Tacke (1996) 'The Mechanism of the Activation of Aromatic Hydrocarbons with Lithium Atoms: Spectroscopic Results and their Ab Initio Interpretation'. 129 :1369-1371. [Details]
M. Tacke (1995) 'Selective Activation of Aromatic C-H Bonds with Lithium Atoms at 77 K '. 128 :91-92. [Details]
M. Tacke, P. Sparrer, R. Teuber, H.-J. Stadter, F. Schuster (1995) 'A Novel Liquid Xenon IR Cell Constructed from a Silicon Single Crystal '. Journal of Molecular Structure, 349 :251-252. [Details]
M. Tacke (1995) 'The Reaction of RLi Species with CO and Isonitriles: IR Spectroscopic Investigations in Liquid Xenon and Ab Initio Calculations of the Intermediates'. 128 :1051-1053. [Details]
M. Tacke (1994) 'Direct Synthesis of ansa-Metallocenes of Tin and Lead via Metal Vapor Cocondensation '. Organometallics, 13 :4124-4125. [Details]
M. Tacke, Ch. Klein, D. J. Stufkens, A. Oskam, P. Jutzi, E. A. Bunte (1993) 'Complexes of Decamethylsilicocene: Cp2Si(CO) and Cp2Si(N2) Z. anorg. allg. Chem., 1993, 619, 865 - 868'. 619 :865-868. [Details]
J. Kroner, H. Noeth, K. Polborn, H. Stolpmann, M. Tacke, M.Thomann (1993) '(Di-tert.-butylphosphanylimino)-(tetramethylpiperidino)boran: ein BNP-1,3-Dipol Chem. Ber'. 126 :1995-2002. [Details]
Ch. Klein, H. Noeth, M. Tacke, M. Thomann (1993) 'Dimere und trimere Aminoalane mit inverser Brueckenfunktion'. Angewandte Chemie-International Edition in English, 32 :886-888. [Details]
M. Tacke, Ch. Klein, D. J. Stufkens, A. Oskam (1993) 'Photochemistry of Cp2Ti(CO)2 and Cp2Ti(N3)2 in solid matrices and in solution at low temperature'. Journal of Organometallic Chemistry, 444 :75-81. [Details]
M. Tacke, H. Kreienkamp, L. Plaggenborg, H. Schnoeckel (1991) 'GaCl: Ein roter metastabiler Festkoerper Z. anorg. allg. Chem. '. 604 :35-38. [Details]
C. Dohmeier, C. Robl, M. Tacke, H. Schnoeckel (1991) 'The Tetrameric Aluminium (I) Compound [AlCp]4'. Angewandte Chemie-International Edition in English*, 30 :564-565. [Details]
R. Koeppe, M. Tacke, H. Schnoeckel (1991) 'Infrarotspektroskopischer Nachweis von monomeren HGaCl2 in festem Argon Z. anorg. allg. Chem'. 605 :35-41. [Details]
R. Ahlrichs, M. Haeser, H. Schnoeckel, M. Tacke (1989) 'Aluminium-Olefin Bonds in Dimeric 1.4.-Dichloro-1.4.-Dialumina-2.5.-Cyclohexadiene'. Chemical Physics Letters, 154 :104-110. [Details]
M. Tacke, H. Schnoeckel (1989) 'Metastable AlCl as a Solid and in Solution '. Inorganic Chemistry, 28 :2895-2896. [Details]
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Other Journals:

O'Connor, K., Gill, C., Tacke, M., Rehmann, F.-J. K., Strohfeldt, K., Sweeney, N., Fitzpatrick, J. M., Watson, R. W. G. (2006) 'Novel Titanocene Anti-Cancer Drugs and their Effect on Apoptosis and the Apoptotic Pathway in Prostate Cancer Cells' Apoptosis . [Details]

M. Tacke (1997) 'Selektive C-H-Aktivierung mit Lithiumatomen: Kryochemische Synthese und spektroskopische Aufklaerung' GIT Fachz. Lab 41 :133-135. [Details]

Conference Publications:

Dowling, C. M., Cuffe, S., Gill, C., Tacke, M., Fitzpatrick, J. M., Watson, R. W. G., (2008) European Urology Supplements Effects of docetaxel and novel titanocene analogues on cell death in prostate cancer following downregulation of Id-1 and the IAPS , pp.276-276 [Details]

Cuffe, S., Dowling, C., Gill, C., Tacke, M., Fitzpatrick, J. M., Carty, M. P., Watson, R. W. G., (2008) Ejc Supplements Novel titanocene analogues induce apoptosis in prostate cancer epithelial cells by initiating a DNA damage response , pp.29-29 [Details]

Dissertations/Theses

M.Tacke (1996) Ungewoehnliche Wege zur Metall-Kohlenstoff-Bindung. Dissertations/Theses [Details]

M. Tacke (1990) Solid and Dissolved AlCl and GaCl: Spectroscopic and Chemical Investigations. Dissertations/Theses [Details]

M. Tacke (1987) Cryochemistry of AlCl with Alkynes and Aromatic Compounds. Dissertations/Theses [Details]