Dr. Oliver Blacque | UCD Conway

Research

Dr Oliver Blacque BSC, MSC, PhD

Peer Reviewed Journals:

Williams CL, Li C, Kida K, Inglis PN, Mohan S, Semenec L, Bialas NJ, Stupay RM, Chen N, Blacque OE*, Yoder BK*, Leroux MR* *co-corresponding (2011) 'MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis'. Journal of Cell Biology, 192 (6):1023-1041. [DOI] [Details]

Jensen VL, Bialas NJ, Bishop-Hurley SL, Molday LL, Kida K, Nguyen PA, Blacque OE, Molday RS, Leroux MR, Riddle DL (2010) 'Localization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25'. PLoS Genetics, 6 (11). [DOI] [Details]

Blacque, OE,Worrall, DM (2002) 'Evidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagen'. Journal of Biological Chemistry, 277 (277):10783-10788. [DOI] [Details]

Kaplan OI, Molla-Herman A, Cevik S, Ghossoub R, Kida K, Kimura Y, Jenkins P, Martens JR, Setou M, Benmerah A, Blacque OE. (2010) 'AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport'. Journal of Cell Science, 123 :3966-3977. [Details]

Kimura Y, Kurabe N, Ikegami K, Tsutsumi K, Konishi Y, Kaplan OI, Kunitomo H, Iino Y, Blacque OE, Setou M. (2010) 'Identification of tubulin deglutamylase among Caenorhabditis elegans and mammalian cytosolic carboxypeptidases (CCPs)'. Journal of Biological Chemistry, .

[Details]

Cevik S, Hori Y, Kaplan OI, Kida K, Toivenon T, Cottell D, Katada T, Kontani K, Blacque OE. (2010) 'Joubert Syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in C. elegans'. Journal of Cell Biology, . [Details]

Inglis, N., Blacque OE, Leroux MR (2009) 'Functional genomics of intraflagellar transport-associated proteins in C. elegans '. Methods in Cell Biology, . [Details]
Bialas NJ, Inglis PN, Li C, Robinson JF, Parker JD, Healey MP, Davis EE, Inglis CD, Toivonen T, Cottell DC, Blacque OE, Quarmby LM, Katsanis N, Leroux MR. (2009) 'Functional interactions between the ciliopathy-associated Meckel syndrome 1(MKS1) protein and two novel MKS1-related (MKSR) proteins'. Journal of Cell Science, 122 (5):611-624. [Details]
Blacque OE, Cevik S, Kaplan OI (2008) 'Intraflagellar transport: from molecular characterisation to mechanism'. Frontiers in Bioscience, 13 :2633-2652. [Details]
Ou G, Koga M, Blacque OE, Murayama T, Ohshima Y, Schafer JC, Li C, Yoder BK,Leroux MR, Scholey JM. (2007) 'Sensory Ciliogenesis in Caenorhabditis elegans: Assignment of IFT components into Distinct Modules Based on Transport and Phenotypic Profiles'. Molecular Biology of the Cell, 18 :1554-1569. [Details]
Pan X, Ou G, Civelekoglu-Scholey G, Blacque OE, Endres NF, Tao L, Mogilner A, Leroux MR, Vale RD, Scholey JM (2006) 'Mechanism of transport of IFT-particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors'. Journal of Cell Biology, 174 :1035-1045. [Details]
Blacque, O.E. & Leroux, M.R. (2006) 'Bardet-Biedl Syndrome: An emerging pathomechanism of intracellular transport'. Cellular and Molecular Life Science, 63 :2145-2161. [Details]
Chen, NS; Mah, A; Blacque, OE; Chu, J; Phgora, K; Bakhoum, MW; Newbury, CRH; Khattra, J; Chan, S; Go, A; Efimenko, E; Johnsen, R; Phirke, P; Swoboda, P; Marra, M; Moerman, DG; Leroux, MR; Baillie, DL; Stein, LD; (2006) 'Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics'. Genome Biology, 7 (12). [Details]
Blacque OE, Li C, Inglis PN, Esmail M, Ou G, Mah AK, Baillie DL, Scholey JM, Leroux MR. (2006) 'The WD repeat-containing protein, IFTA-1, is required for effective retrograde intraflagellar transport'. Molecular Biology of the Cell, 17 :5053-5062. [Details]
Efimenko E, Blacque OE, Ou G, Haycraft CJ, Yoder BK, Scholey JM, Leroux MR, Swoboda P. (2006) 'C. elegans DYF-2, anortholog of human WDR19, is a component of the IFT machinery in sensory cilia'. Molecular Biology of the Cell, . [Details]
Ou G, Blacque OE, Snow JJ, Leroux MR, Scholey JM. (2005) 'Functional coordination of intraflagellar transport motors'. NATURE, 436 :583-587. [Details]
Blacque OE, Perens E, Boroevich KA, Inglis PN, Li C, Warner A, Khattra J, Holt RA, Ou G, Mah AK, McKay SJ, Huang P, Swoboda P, Jones SJM, Marra MA, Baillie DL, Moerman DG, Shaham S, Leroux MR. (2005) 'Functional Genomics of the Cilium, a Sensory Organelle'. Curr. Biol, 15 :935-941. [Details]
Fan Y, Esmail MA, Ansley SJ, Blacque OE, Boroevich K, Ross AJ, Moore SJ, Badano JL, May-Simera H, Compton DS, Green JS, Lewis RA, van Haelst MM, Parfrey PS, Baillie DL, Beales PL, Katsanis N, Davidson WS, Leroux MR. (2004) 'Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome'. NATURE GENETICS, 36 :989-993. [Details]
Blacque OE, Reardon MJ, Li C, McCarthy J, Mahjoub MR, Ansley SJ, Badano JL, Mah AK, Beales PL, Davidson WS, Johnsen RC, Audeh M, Plasterk RH, Baillie DL, Katsanis N, Quarmby LM, Wicks SR, Leroux MR. (2004) 'Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport'. GENES & DEVELOPMENT, 18 :1630-1642. [Details]
Li JB, Gerdes JM, Haycraft CJ, Fan Y, Teslovich TM, May-Simera H, Li H, Blacque OE, Li L, Leitch CC, Lewis RA, Green JS, Parfrey PS, Leroux MR, Davidson WS, Beales PL, Guay-Woodford LM, Yoder BK, Stormo GD, Katsanis N, Dutcher SK. (2004) 'Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene'. CELL, 117 :541-552. [Details]
Ansley SJ, Badano JL, Blacque OE, Hill J, Hoskins BE, Leitch CC, Kim JC, Ross AJ, Eichers ER, Teslovich TM, Mah AK, Johnsen RC, Cavender JC, Lewis RA, Leroux MR, Beales PL, Katsanis N. Equal contributions. (2003) 'Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome'. Nature, (425):628-633. [Details]
Worrall, DM; Blacque, OE; Barnes, RC; (1999) 'The expanding superfamily of serpins: searching for the real targets'. Biochemical Society Transactions, 27 (4):746-750. [Details]
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