Dr. Orina Belton | UCD Conway

Research

Dr Orina Belton B.Sc., Ph.D.

Books:

Maguire PB, Belton O, O¿Donoghue N & Coppinger JC. (2007) Platelet-endothelial interactions in, The Endothelium: A Comprehensive Reference. Cambridge, UK: Cambridge Univerity Press. [Details]

Book Chapters:

Belton O, McClelland S, Fitzgerald D (2007) 'Cycloxygenase inhibition in atherothrombotic disease' In: A Clinical Guide to the use of Antithrombotic Drugs in Coronary Artery Disease. London: Informa Healthcare. [Details]

Maguire PB, Belton O, O'Donoghue N and Coppinger JC. (2005) 'Platelet-endothelial interactions' In: William C. Aird (eds). The Endothelium: A Comprehensive Reference. Cambridge, UK: Cambridge Univerity Press. [Details]

Belton O, Forde R, Lorez HP, Fitzgerald DJ. (1998) 'Cyclooxygenase expression in a rat model of focal cerebral ischemia' In: Essential Fatty Acids and Eicosanoids. *: AOCS Press. [Details]

Peer Reviewed Journals:

McClelland S, Cox C, O'Connor R, de Gaetano M, McCarthy C, Cryan L, Fitzgerald D, Belton O (2010) 'Conjugated linoleic acid suppresses the migratory and inflammatory phenotype of the monocyte/macrophage cell'. Atherosclerosis, 211 (1):96-102. [DOI] [Details]

McCarthy C, O'Gaora P, James WG, McClelland S, Fitzgerald DJ, Belton O (2010) 'SorLA modulates atheroprotective properties of CLA by regulating monocyte migration'. Atherosclerosis, . [DOI] [Details]

Belton O, McClelland S, Gawaz M, Kennerknecht E, Konrad CS, Sauer S, Schuerzinger K, Massberg S, Fitzgerald DJ, (2009) 'Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse'. Atherosclerosis, 202 (1):84-91. [DOI] [Details]

Belton O, McClelland S, Gawaz M, Kennerknecht E, Konrad CS, Sauer S, Schuerzinger K, Massberg S, Fitzgerald DJ, (2008) 'Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse'. Atherosclerosis, (NA). [DOI] [Details]

McClelland, SE, Ballou, LR, Fitzgerald, DJ, Belton, OA, (2007) 'COX-2 gene deletion increases advanced aortic arch atherosclerosis in the ApoE-/- mouse model'. ARTERIOSCL THROM VAS, 27 :97-97. [Details]

McClelland, SE, OConnor, R, Buckmaster, PE, Fitzgerald, DJ, Belton, OA, (2007) 'Conjugated linoleic acid alters the pro-atherosclerotic phenotype of the monocyte/macrophage - Evidence for the involvement of a novel signalling pathway'. Atherosclerosis Supp, 8 :42-42. [Details]

Toomey S, Roche H, Fitzgerald D, Belton O. (2003) 'Regression of pre-established atherosclerosis in the apoE-/- mouse by conjugated linoleic acid'. Biochemical Society Transactions, 31 (5):1075-1079. [Details]
Toomey, S; Harhen, B; Roche, HM; Fitzgerald, D; Belton, O; (2006) 'Profound resolution of early atherosclerosis with conjugated linoleic acid'. Atherosclerosis, 187 (1):40-49. [Details]
Pidgeon GP, Tamosiuniene R, Chen G, Leonard I, Belton O, Bradford A, Fitzgerald DJ. (2004) 'Intravascular thrombosis after hypoxia-induced pulmonary hypertension: regulation by cyclooxygenase-2'. Circulation, 110 (17):2701-2707. [Details]
Coppinger JA, Cagney G, Toomey S, Kislinger T, Belton O, McRedmond JP, Cahill DJ, Emili A, Fitzgerald DJ, Maguire PB (2004) 'Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions'. Blood, 103 (6):2096-2104. [Details]
Belton O, Duffy A, Toomey S, Fitzgerald DJ. (2003) 'Cyclooxygenase isoforms and platelet vessel wall interactions in the apolipoprotein E knockout mouse model of atherosclerosis'. Circulation, 108 (24):3017-3023. [Details]
Duffy T, Belton O, Bresnihan B, FitzGerald O, FitzGerald D (2003) 'Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis'. Drugs, 63 (Suppl 1):31-36. [Details]
Belton O, Fitzgerald D. (2003) 'Cyclooxygenase-2 inhibitors and atherosclerosis'. Journal of the American College of Cardiology, 41 (10):1820-1822. [Details]
Murphy JF, Steele C, Belton O, Fitzgerald DJ. (2003) 'Induction of cyclooxygenase-1 and -2 modulates angiogenic responses to engagement of alphavbeta3'. British Journal of Haematology, 121 (1):157-164. [Details]
Belton O, Fitzgerald DJ. (2003) 'Cyclooxygenase isoforms and atherosclerosis'. Expert Rev Mol Med, :1-18. [Details]
Connolly E, Bouchier-Hayes DJ, Kaye E, Leahy A, Fitzgerald D, Belton O (2002) 'Cyclooxygenase isozyme expression and intimal hyperplasia in a rat model of balloon angioplasty'. Journal of Pharmacology and Experimental Therapeutics, 300 (2):393-398. [Details]
Belton O, Byrne D, Kearney D, Leahy A, Fitzgerald DJ. (2000) 'Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis'. Circulation, 102 (8):840-845. [Details]
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Conference Publications:

McCarthy C, Mooney D, Fitzgerald DJ, Belton O (2010) Identification of a PGC1a regulated network induced by conjugated linoleic acid in the regression of atherosclerosis In Atherosclerosis Thrombosis and Vascular Biology [Details]

Belton O, McClelland S, Gawaz M, Kennerknecht E, Konrad CS, Sauer S, Schuerzinger K, Massberg S, Fitzgerald DJ, (2008) Atherosclerosis Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse [DOI] [Details]

McClelland S, Ballou L, Fitzgerald D, Belton O (2007) COX-2 gene deletion increases advanced aortic arch atherosclerosis in the apoE-/- mouse model 8th Annual Conference on Atherosclerosis Thrombosis and Vascular Biology [Details]

McCarthy C, James W, Fitzgerald DJ, Belton O (2010) Novel regulation and recognition of the role of SorLA in atherosclerotic vasculature Keystone Symposia Advances in Molecular Mechanisms in Atherosclerosis 2010 [Details]

McClelland S, Fitzgerald D, Belton O (2007) Conjugated linoleic acid alters the pro-atherosclerotic phenotype of the monocyte/macrophage- evidence for the involvement of a novel signalling pathway European Atherosclerosis Society 76th Congress [Details]

McClelland S, Fitzgerald D, Langenbach R, Belton O (2004) Cyclooxygenase-1 Gene Deletion Inhibits Atherosclerosis in the ApoE-/- Mouse 5th Annual Conference on Atherosclerosis Thrombosis and Vascular Biology [Details]

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Abstract

Toomey SM, Sharkey CT, Dooley CM, Fitzgerald DJ, and Belton OA. (2004) The effect of a novel inhibitor of the peroxidase activity of cyclooxygenase-1 on the development of atherosclerosis. Abstract [Details]

Toomey SM, Dooley CM, Sharkey CT, Roche HM, Fitzgerald DJ, and Belton OA. (2003) Profound resolution of atherosclerotic lesions by the 9-cis, 11-trans isomer of Conjugated Linoleic Acid. Abstract [Details]

Toomey S, Dooley C, Sharkey C, Fitzgerald D, Belton O (2004) The effect of a novel inhibitor of the peroxidase activity of cyclooxygenase-1 on the development of atherosclerosis 5th Annual Conference on Atherosclerosis Thrombosis and Vascular Biology [Details]
Toomey S, Roche HM, Fitzgerald D & Belton O (2003) Regression of pre-established atherosclerosis in the apoE-/- mouse by conjugated linoleic acid Biochemisty Society Meeting , pp.1075-1079 [Details]
Toomey S, Roche H, Fitzgerald D, Belton O (2003) Profound resolution of atherosclerotic lesions by the 9-cis, 11-trans isomer of conjugated linoleic acid 4th Annual Conference on Atherosclerosis Thrombosis and Vascular Biology [Details]
Duffy A, Fitzgerald D, Belton O (2001) Inhibition of cyclooxygenase isoforms and the development of atherosclerosis American Heart Association, 74th Scientific Sessions [Details]
Connolly E, Leahy A, Fitzgerald D, Belton O (2000) Effect of selective Cyclooxygenase-1 and '2 inhibition on intimal hyperplasia in a rat model of balloon angioplasty American Heart Association, 73rd Scientific Sessions [Details]
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