Dr. Seamas Donnelly | UCD Conway

Research

Dr Seamas Donnelly MB MD FRCPI

Peer Reviewed Journals:

Conroy H, Mawhinney L, Donnelly SC (2010) 'Inflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link'. QJM : monthly journal of the Association of Physicians, 103 (11):831-836. [DOI] [Details]

Govender P, Dunn MJ, Donnelly SC (2009) 'Proteomics and the lung: Analysis of bronchoalveolar lavage fluid'. Proteomics Clinical Applications, 2 :1044-1051. [Details]

Reid CJ, Thompson L, Donnelly S, Deaton CM, Marlin DJ, Carrington SD, Irwin JA (2009) 'The activity and expression of chitinase in the equine lung and its activity in normal horses and animals with recurrent airway obstruction'. Research in Veterinary Science, 87 (1):20-25. [DOI] [Details]

Martos, R,Baugh, J,Ledwidge, M,O'Loughlin, C,Murphy, NF,Conlon, C,Patle, A,Donnelly, SC,McDonald, K (2009) 'Diagnosis of heart failure with preserved ejection fraction: improved accuracy with the use of markers of collagen turnover'. European Journal of Heart Failure, 11 :191-197. [DOI] [Details]

Ryan, K,Leonard, M,Guerin, S,Donnelly, S,Conroy, M,Meagher, D (2009) 'Validation of the confusion assessment method in the palliative care setting'. Palliative Medicine, 23 :40-45. [DOI] [Details]

Cooke, G,Armstrong, ME,Donnelly, SC (2009) 'Macrophage migration inhibitory factor (MIF), enzymatic activity and the inflammatory response'. Biofactors, 35 :165-168. [DOI] [Details]

Harte, S.,McNicholas, W. T.,Donnelly, S. C.,Dodd, J. D. (2008) 'Honeycomb cysts in idiopathic pulmonary haemosiderosis: high-resolution CT appearances in two adults'. Br J Radiol, 81 (972):e295-8. [Details]
Armstrong, M. E., Gantier, M., Li, L. L., Chung, W. Y., McCann, A., Baugh, J. A., Donnelly, S. C., (2008) 'Small interfering RNAs induce macrophage migration inhibitory factor production and proliferation in breast cancer cells via a double-stranded RNA-dependent protein kinase-dependent mechanism'. Immunology, 180 (11):7125-7133. [Details]
Chappell, S,Daly, L,Morgan, K,Guetta-Baranes, T,Roca, J,Rabinovich, R,Lotya, J,Millar, AB,Donnelly, SC,Keatings, V,MacNee, W,Stolk, J,Hiemstra, PS,Miniati, M,Monti, S,O'Connor, CM,Kalshelker, N (2008) 'Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD'. EUR RESPIR J, 32 :931-937. [DOI] [Details]
Armstrong, ME,Gantier, M,Li, LL,Chung, WY,McCann, A,Baugh, JA,Donnelly, SC (2008) 'Small interfering RNAs induce macrophage migration inhibitory factor production and proliferation in breast cancer cells via a double-stranded RNA-dependent protein kinase-dependent mechanism'. J IMMUNOL, 180 :7125-7133. [Details]
Kalsheker N, Chappell S, Daly L, Morgan K, Guetta-Baranes T, Roca J, Rabinovich R, Lotya J, Millar AB, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, (2008) 'Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD'. EUR RESPIR J, 32 (4):931-937. [DOI] [Details]
Dodd JD, Harte S, McNicholas WT, Donnelly SC, (2008) 'Honeycomb cysts in idiopathic pulmonary haemosiderosis: high-resolution CT appearances in two adults'. British Journal of Radiology, 81 (972):1-8. [DOI] [Details]
Kalsheker N, Chappell S, Daly L, Morgan K, Guetta-Baranes T, Roca J, Rabinovich R, Lotya J, Millar AB, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, (2008) 'Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD'. EUR RESPIR J, 4 (NA):931-937. [DOI] [Details]
Chappell S, Daly L, Morgan K, Baranes TG, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, Macnee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, Kalsheker N. (2007) 'Variation in the tumour necrosis factor gene is not associated with susceptibility to COPD'. European Respiratory Journal, 30 (4):810-812. [Details]
Foley, S. C.,Hopkins, N. O.,Fitzgerald, M. X.,Donnelly, S. C.,McLoughlin, P. (2007) 'Airway nitric oxide output is reduced in bronchiectasis'. Respir Med, 101 (7):1549-55. [Details]
Gantier, MP,Baugh, JA,Donnelly, SC (2007) 'Nuclear transcription of long hairpin RNA triggers innate immune responses'. Cytokine, 27 :789-797. [DOI] [Details]
Govender P, Baugh JA, Pennington SR, Dunn MJ, Donnelly SC. (2007) 'Role of proteomics in the investigation of pulmonary fibrosis'. Expert Rev Proteomics, 4 (3):379-388. [Details]
Govender, P.,Baugh, J. A.,Pennington, S. R.,Dunn, M. J.,Donnelly, S. C. (2007) 'Role of proteomics in the investigation of pulmonary fibrosis'. Expert Rev Proteomics, 4 (3):379-88. [Details]
Kalsheker N, Chappell S, Daly L, Morgan K, Baranes TG, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, Macnee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, (2007) 'Variation in the tumour necrosis factor gene is not associated with susceptibility to COPD'. EUR RESPIR J, 4 (NA):810-812. [DOI] [Details]
Govender, P.,Baugh, J. A.,Pennington, S. R.,Dunn, M. J.,Donnelly, S. C. (2007) 'Role of proteomics in the investigation of pulmonary fibrosis'. Expert Rev Proteomics, 4 (3):379-88. [Details]
Dawson KA, Cedervall T, Lynch I, Foy M, BerggÃ¥rd T, Donnelly SC, Cagney G, Linse S, (2007) 'Detailed identification of plasma proteins adsorbed on copolymer nanoparticles'. Angewandte Chemie (International ed. in English), 46 (30):5754-5756. [DOI] [Details]
Dawson KA, Cedervall T, Lynch I, Foy M, BerggÃ¥rd T, Donnelly SC, Cagney G, Linse S, (2007) 'Detailed identification of plasma proteins adsorbed on copolymer nanoparticles'. Angewandte Chemie (International ed. in English), 46 (30):5754-5756. [DOI] [Details]
Martos R, Baugh J, Ledwidge M, O'Loughlin C, Conlon C, Patle A, Donnelly S, McDonald K. (2007) 'Diastolic Heart Failure: Evidence of increased myocardial collagen turnover linked to diastolic dysfunction'. Circulation, 115 :888-895. [Details]
Govender, P.,Baugh, J. A.,Pennington, S. R.,Dunn, M. J.,Donnelly, S. C. (2007) 'Role of proteomics in the investigation of pulmonary fibrosis'. Expert Rev Proteomics, 4 (3):379-88. [Details]
Foley, SC, Hopkins, NO, Fitzgerald, MX, Donnelly, SC, McLoughlin, P, (2007) 'Airway nitric oxide output is reduced in bronchiectasis'. Respiratory Medicine, 101 :1549-1555. [Details]
Martos, R; Baugh, J; Ledwidge, M; O'Loughlin, C; Conlon, C; Patle, A; Donnelly, SC; McDonald, K; (2007) 'Diastolic heart failure - Evidence of increased myocardial collagen turnover linked to diastolic dysfunction'. Circulation, 115 (7):888-895. [Details]
Plant, BJ; Ghani, S; O'Mahony, MJ; Morgan, L; O'Connor, CM; Morgan, K; Baugh, JA; Donnelly, SC; (2007) 'Sarcoidosis and MIF gene polymorphism: a case-control study in an Irish population'. European Respiratory Journal, 29 (2):325-329. [Details]
Plant, BJ; Ghani, S; O'Mahony, MJ; Morgan, L; O'Connor, CM; Morgan, K; Baugh, JA; Donnelly, SC; (2007) 'Sarcoidosis and MIF gene polymorphism: a case-control study in an Irish population'. European Respiratory Journal, 29 (2):325-329. [Details]
Martos, R,Baugh, J,Ledwidge, M,O'Loughlin, C,Conlon, C,Patle, A,Donnelly, SC,McDonald, K (2007) 'Diastolic heart failure - Evidence of increased myocardial collagen turnover linked to diastolic dysfunction'. Circulation, 115 :888-895. [DOI] [Details]
Bucala, R,Donnelly, SC (2007) 'Macrophage migration inhibitory factor: A probable link between inflammation and cancer'. Immunity, 26 :281-285. [Details]
Plant, BJ,Ghani, S,O'Mahony, MJ,Morgan, L,O'Connor, CM,Morgan, K,Baugh, JA,Donnelly, SC (2007) 'Sarcoidosis and MIF gene polymorphism: a case-control study in an Irish population'. EUR RESPIR J, 29 :325-329. [DOI] [Details]
Foley, SC,Hopkins, NO,Fitzgerald, MX,Donnelly, SC,McLoughlin, P (2007) 'Airway nitric oxide output is reduced in bronchiectasis'. Respiratory Medicine, 101 :1549-1555. [DOI] [Details]
Govender, P.,Baugh, J. A.,Pennington, S. R.,Dunn, M. J.,Donnelly, S. C. (2007) 'Role of proteomics in the investigation of pulmonary fibrosis'. Expert Rev Proteomics, 4 (3):379-88. [Details]
Govender P, Baugh JA, Pennington SR, Dunn MJ, Donnelly SC. (2007) 'Role of proteomics in the investigation of pulmonary fibrosis'. Expert Review of Proteomics, 4 (3):379-388. [Details]
Foley, S. C.,Hopkins, N. O.,Fitzgerald, M. X.,Donnelly, S. C.,McLoughlin, P. (2007) 'Airway nitric oxide output is reduced in bronchiectasis'. Respir Med, 101 (7):1549-55. [Details]
Cedervall, T.,Lynch, I.,Foy, M.,Berggard, T.,Donnelly, S. C.,Cagney, G.,Linse, S.,Dawson, K. A. (2007) 'Detailed identification of plasma proteins adsorbed on copolymer nanoparticles'. Angew Chem Int Ed Engl, 46 (30):5754-6. [Details]
Govender, P.,Baugh, J. A.,Pennington, S. R.,Dunn, M. J.,Donnelly, S. C. (2007) 'Role of proteomics in the investigation of pulmonary fibrosis'. Expert Rev Proteomics, 4 (3):379-88. [Details]
Bucala, R.,Donnelly, S. C. (2007) 'Macrophage migration inhibitory factor: a probable link between inflammation and cancer'. Immunity, 26 (3):281-5. [Details]
Chappell, S,Daly, L,Morgan, K,Baranes, TG,Roca, J,Rabinovich, R,Millar, A,Donnelly, SC,Keatings, V,MacNee, W,Stolk, J,Hiemstra, P,Miniati, M,Monti, S,O'Connor, CM,Kalsheker, N (2006) 'Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease'. Human Mutation, 27 :103-109. [DOI] [Details]
Chappell, S; Daly, L; Morgan, K; Baranes, TG; Roca, J; Rabinovich, R; Millar, A; Donnelly, SC; Keatings, V; MacNee, W; Stolk, J; Hiemstra, PS; Miniati, M; Monti, S; O'Connor, CM; Kalsheker, N; (2006) 'The SERPINE2 gene and chronic obstructive pulmonary disease'. American Journal of Human Genetics, 79 (1):184-186. [Details]
Chappell S, Daly L, Morgan K, Baranes TG, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, Kalsheker N. (2006) 'The SERPINE2 gene and chronic obstructive pulmonary disease'. American Journal of Human Genetics, 79 (1):184-186. [Details]
Baugh, JA; Gantier, M; Li, L; Byrne, A; Buckley, A; Donnelly, SC; (2006) 'Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1'. Biochemical and Biophysical Research Communications, 347 (4):895-903. [Details]
Baugh, JA; Gantier, M; Li, L; Byrne, A; Buckley, A; Donnelly, SC; (2006) 'Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1'. Biochemical and Biophysical Research Communications, 347 (4):895-903. [Details]
Martos, R; Baugh, J; Ledwidge, M; Loughlin, CO; Conlon, C; Donnelly, S; Mc Donald, K; (2006) 'Elevated plasma markers of matrix metalloproteinases type 2 and 9 are independent predictors of diastolic heart failure'. EUROPEAN HEART JOURNAL, 27 (NA):844-844. [Details]
Martos, R; Patle, A; Baugh, J; Ledwidge, M; Loughlin, CO; Conlon, C; Donnelly, S; Mc Donald, K; (2006) 'The role of myocardial fibrotic markers in detecting different stages of diastolic dysfunction in a hypertensive population'. EUROPEAN HEART JOURNAL, 27 (NA):300-300. [Details]
Chappell, S; Daly, L; Morgan, K; Baranes, TG; Roca, J; Rabinovich, R; Millar, A; Donnelly, SC; Keatings, V; MacNee, W; Stolk, J; Hiemstra, P; Miniati, M; Monti, S; O'Connor, CM; Kalsheker, N; (2006) 'Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease'. Human Mutation, 27 (1):103-109. [Details]
Baugh, JA; Gantier, M; Li, L; Byrne, A; Buckley, A; Donnelly, SC; (2006) 'Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1'. Biochemical and Biophysical Research Communications, 347 (4):895-903. [Details]
Baugh, JA,Gantier, M,Li, L,Byrne, A,Buckley, A,Donnelly, SC (2006) 'Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1'. Biochemical and Biophysical Research Communications, 347 :895-903. [DOI] [Details]
Baugh JA, Gantier M, Li L, Byrne A, Buckley A, Donnelly SC. (2006) 'Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1'. Biochemical and Biophysical Research Communications, 347 (4):895-903. [Details]
Chappell S, Daly L, Morgan K, Baranes TG, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra P, Miniati M, Monti S, O'Connor CM, Kalsheker N. (2006) 'Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease'. HUMAN MUTATION, 27 (1):103-109. [Details]
Naji, N. A.,Connor, M. C.,Donnelly, S. C.,McDonnell, T. J. (2006) 'Effectiveness of pulmonary rehabilitation in restrictive lung disease'. J Cardiopulm Rehabil, 26 (4):237-43. [Details]
Plant, B.J., Gallagher, C.G., Bucala, R., Baugh, J.A., Chappell, S., Morgan, L., O'Connor, C.M., Morgan, K., Donnelly, S.C. (2005) 'Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism'. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDIC, 172 (11):1412-1415. [Details]
Plant, BJ,Gallagher, CG,Bucala, R,Baugh, JA,Chappell, S,Morgan, L,O'Connor, CM,Morgan, K,Donnelly, SC (2005) 'Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism'. American Journal of Respiratory and Critical Care Medicine, 172 :1412-1415. [DOI] [Details]
Mizue, Y,Ghani, S,Leng, L,McDonald, C,Kong, P,Baugh, J,Lane, SJ,Craft, J,Nishihira, J,Donnelly, SC,Zhu, Z,Bucala, R (2005) 'Role for macrophage migration inhibitory factor in asthma'. Proceedings of the National Academy of Sciences of the United States of America, 102 :14410-14415. [DOI] [Details]
Plant, BJ; Gallagher, CG; Bucala, R; Baugh, JA; Chappell, S; Morgan, L; O'Connor, CM; Morgan, K; Donnelly, SC; (2005) 'Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism'. American Journal of Respiratory and Critical Care Medicine, 172 (11):1412-1415. [Details]
Mizue, Y; Ghani, S; Leng, L; McDonald, C; Kong, P; Baugh, J; Lane, SJ; Craft, J; Nishihira, J; Donnelly, SC; Zhu, Z; Bucala, R; (2005) 'Role for macrophage migration inhibitory factor in asthma'. Proceedings of the National Academy of Sciences of the United States of America, 102 (40):14410-14415. [Details]
Martos, R; Baugh, J; O'Loughlin, C; Ledwidge, M; Donnelly, S; McDonald, K; (2005) 'Diastolic heart failure is associated with elevated serum markers of collagen turnover'. EUROPEAN HEART JOURNAL, 26 (NA):602-602. [Details]
Plant, BJ; Gallagher, CG; Bucala, R; Baugh, JA; Chappell, S; Morgan, L; O'Connor, CM; Morgan, K; Donnelly, SC; (2005) 'Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism'. American Journal of Respiratory and Critical Care Medicine, 172 (11):1412-1415. [Details]
Plant, B. J.,Gallagher, C. G.,Bucala, R.,Baugh, J. A.,Chappell, S.,Morgan, L.,O'Connor, C. M.,Morgan, K.,Donnelly, S. C. (2005) 'Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism'. Am J Respir Crit Care Med, 172 (11):1412-5. [Details]
Mizue, Y., Ghani, S., Leng, L., McDonald, C., Kong, P., Baugh, J., Lane, S.J., Craft, J., Nishihira, J., Donnelly, S.C., Zhu, Z., Bucala, R. (2005) 'Role for macrophage migration inhibitory factor in asthma'. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE, 102 (40):14410-14415. [Details]
Plant, BJ; Baugh, JA; Chappell, S; Morgan, L; Keatings, V; O'Connor, C; Morgan, K; Donnelly, SC; (2004) 'The role of a macrophage migration inhibitory factor (MIF) functional polymorphism in chronic obstructive pulmonary disease'. Thorax, 59 (1):69-69. [Details]
Fisher, AJ,Donnelly, SC,Pritchard, G,Dark, JH,Corris, PA (2004) 'Objective assessment of criteria for selection of donor lungs suitable for transplantation'. Thorax, 59 :434-437. [DOI] [Details]
Plant, BJ; Baugh, JA; Chappell, S; Morgan, L; Keatings, V; O'Connor, C; Morgan, K; Donnelly, SC; (2004) 'The role of a macrophage migration inhibitory factor (MIF) functional polymorphism in chronic obstructive pulmonary disease'. Thorax, 59 (1):69-69. [Details]
Leng, L; Metz, CN; Fang, Y; Xu, J; Donnelly, S; Baugh, J; Delohery, T; Chen, YB; Mitchell, RA; Bucala, R; (2003) 'MIF signal transduction initiated by binding to CD74'. Experimental Medicine, 197 (11):1467-1476. [Details]
Plant, BJ; Gallagher, CG; Baugh, JA; Plummer, S; Morgan, L; O'Connor, C; Morgan, K; Donnelly, SC; (2003) 'The role of a macrophage migration inhibitory factor (MIF) functional polymorphism in adult cystic fibrosis disease severity'. Thorax, 58 (NA):20-20. [Details]
Leng, L,Metz, CN,Fang, Y,Xu, J,Donnelly, S,Baugh, J,Delohery, T,Chen, YB,Mitchell, RA,Bucala, R (2003) 'MIF signal transduction initiated by binding to CD74'. Experimental Medicine, 197 :1467-1476. [DOI] [Details]
Plant, BJ; Gallagher, CG; Baugh, JA; Plummer, S; Morgan, L; O'Connor, C; Morgan, K; Donnelly, SC; (2003) 'The role of a macrophage migration inhibitory factor (MIF) functional polymorphism in adult cystic fibrosis disease severity'. Thorax, 58 (NA):20-20. [Details]
Baugh JA, Donnelly SC. (2003) 'Macrophage migration inhibitory factor: a neuroendocrine modulator of chronic inflammation'. Journal of Endocrinology, 179 (1):15-23. [Details]
Keane, MP,Donnelly, SC,Belperio, JA,Goodman, RB,Dy, M,Burdick, MD,Fishbein, MC,Strieter, RM (2002) 'Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome'. J IMMUNOL, 169 :6515-6521. [Details]
Keane, MP, Donnelly, SC, Belperio, JA, Goodman, RB, Dy, M, Burdick, MD, Fishbein, MC, Strieter, RM, (2002) 'Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome'. J IMMUNOL, 169 (11):6515-6521. [Details]
O'Reilly, KMA; Baugh, JA; Plant, BJ; Fitzgerald, MX; Bucala, R; Donnelly, SC; (2002) 'Macrophage Migration Inhibitory Factor induces proliferation and has pro-fibrotic effects in primary human pulmonary fibroblasts'. Thorax, 57 (NA). [Details]
Baugh JA, Chitnis S, Donnelly SC, Monteiro J, Lin X, Plant BJ, Wolfe F, Gregersen PK, Bucala R. (2002) 'A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis'. Genes and Immunity, 3 (3):170-176. [Details]
CROWLEY, JJ,DONNELLY, SM,TOBIN, M,FITZGERALD, O,BRESNIHAN, B,MAURER, BJ,QUIGLEY, PJ (1993) 'DOPPLER-ECHOCARDIOGRAPHIC EVIDENCE OF LEFT-VENTRICULAR DIASTOLIC DYSFUNCTION IN ANKYLOSING-SPONDYLITIS'. American Journal of Cardiology, 71 :1337-1340. [Details]
Plant, BJ; Ghani, S; O'Mahony, MJ; Morgan, L; O'Connor, CM; Morgan, K; Baugh, JA; Donnelly, SC; (2007) 'Sarcoidosis and MIF gene polymorphism: a case-control study in an Irish population'. European Respiratory Journal, 29 (2):325-329. [Details]
Martos, R; Baugh, J; Ledwidge, M; O'Loughlin, C; Conlon, C; Patle, A; Donnelly, SC; McDonald, K; (2007) 'Diastolic heart failure - Evidence of increased myocardial collagen turnover linked to diastolic dysfunction'. Circulation, 115 (7):888-895. [Details]
Chappell, S; Daly, L; Morgan, K; Baranes, TG; Roca, J; Rabinovich, R; Millar, A; Donnelly, SC; Keatings, V; MacNee, W; Stolk, J; Hiemstra, P; Miniati, M; Monti, S; O'Connor, CM; Kalsheker, N; (2006) 'Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease'. Human Mutation, 27 (1):103-109. [Details]
Baugh, JA; Gantier, M; Li, L; Byrne, A; Buckley, A; Donnelly, SC; (2006) 'Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1'. Biochemical and Biophysical Research Communications, 347 (4):895-903. [Details]
Martos, R; Patle, A; Baugh, J; Ledwidge, M; Loughlin, CO; Conlon, C; Donnelly, S; Mc Donald, K; (2006) 'The role of myocardial fibrotic markers in detecting different stages of diastolic dysfunction in a hypertensive population'. EUROPEAN HEART JOURNAL, 27 (NA):300-300. [Details]
Martos, R; Baugh, J; Ledwidge, M; Loughlin, CO; Conlon, C; Donnelly, S; Mc Donald, K; (2006) 'Elevated plasma markers of matrix metalloproteinases type 2 and 9 are independent predictors of diastolic heart failure'. EUROPEAN HEART JOURNAL, 27 (NA):844-844. [Details]
Plant, B.J., Ghani, S., O'mahony, M.J., Morgan, L., O'connor, C.M., Morgan, K., Baugh, J.A. Donnelly, S.C. (2006) 'Sarcoidosis and a MIF gene polymorphism: a case-control study in an Irish Population'. EUROPEAN RESPIRATORY JOURNAL, . [Details]
Baugh, JA; Gantier, M; Li, L; Byrne, A; Buckley, A; Donnelly, SC; (2006) 'Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1'. Biochemical and Biophysical Research Communications, 347 (4):895-903. [Details]
Chappell, S; Daly, L; Morgan, K; Baranes, TG; Roca, J; Rabinovich, R; Millar, A; Donnelly, SC; Keatings, V; MacNee, W; Stolk, J; Hiemstra, PS; Miniati, M; Monti, S; O'Connor, CM; Kalsheker, N; (2006) 'The SERPINE2 gene and chronic obstructive pulmonary disease'. American Journal of Human Genetics, 79 (1):184-186. [Details]
Martos, R; Baugh, J; O'Loughlin, C; Ledwidge, M; Donnelly, S; McDonald, K; (2005) 'Diastolic heart failure is associated with elevated serum markers of collagen turnover'. EUROPEAN HEART JOURNAL, 26 (NA):602-602. [Details]
Mizue, Y; Ghani, S; Leng, L; McDonald, C; Kong, P; Baugh, J; Lane, SJ; Craft, J; Nishihira, J; Donnelly, SC; Zhu, Z; Bucala, R; (2005) 'Role for macrophage migration inhibitory factor in asthma'. Proceedings of the National Academy of Sciences of the United States of America, 102 (40):14410-14415. [Details]
Plant, BJ; Gallagher, CG; Bucala, R; Baugh, JA; Chappell, S; Morgan, L; O'Connor, CM; Morgan, K; Donnelly, SC; (2005) 'Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism'. American Journal of Respiratory and Critical Care Medicine, 172 (11):1412-1415. [Details]
Fisher, AJ; Donnelly, SC; Pritchard, G; Dark, JH; Corris, PA; (2004) 'Objective assessment of criteria for selection of donor lungs suitable for transplantation'. Thorax, 59 (5):434-437. [Details]
Plant, BJ; Baugh, JA; Chappell, S; Morgan, L; Keatings, V; O'Connor, C; Morgan, K; Donnelly, SC; (2004) 'The role of a macrophage migration inhibitory factor (MIF) functional polymorphism in chronic obstructive pulmonary disease'. Thorax, 59 (1):69-69. [Details]
Mulcahy, G; O'Neill, S; Donnelly, S; Dalton, JP; (2004) 'Helminths at mucosal barriers - interaction with the immune system'. ADVANCED DRUG DELIVERY REVIEWS, 56 (6):853-868. [Details]
Plant, BJ; Gallagher, CG; Baugh, JA; Plummer, S; Morgan, L; O'Connor, C; Morgan, K; Donnelly, SC; (2003) 'The role of a macrophage migration inhibitory factor (MIF) functional polymorphism in adult cystic fibrosis disease severity'. Thorax, 58 (NA):20-20. [Details]
Leng, L; Metz, CN; Fang, Y; Xu, J; Donnelly, S; Baugh, J; Delohery, T; Chen, YB; Mitchell, RA; Bucala, R; (2003) 'MIF signal transduction initiated by binding to CD74'. Experimental Medicine, 197 (11):1467-1476. [Details]
Baugh, JA; Donnelly, SC; (2003) 'Macrophage migration inhibitory factor: a neuroendocrine modulator of chronic inflammation'. Journal of Endocrinology, 179 (1):15-23. [Details]
Dalton, JP; Brindley, PJ; Knox, DP; Brady, CP; Hotez, PJ; Donnelly, S; O'Neill, SM; Mulcahy, G; Loukas, A; (2003) 'Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression'. International Journal for Parasitology, 33 (5-6):621-640. [Details]
O'Reilly, KMA; Baugh, JA; Plant, BJ; Fitzgerald, MX; Bucala, R; Donnelly, SC; (2002) 'Macrophage Migration Inhibitory Factor induces proliferation and has pro-fibrotic effects in primary human pulmonary fibroblasts'. Thorax, 57 (NA). [Details]
Baugh JA, Chitnis S, Donnelly SC, Monteiro J, Lin X, Plant BJ, Wolfe F, Gregersen PK, Bucala R. (2002) 'A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis'. Genes and Immunity, 3 :170-176. [Details]
Fisher, A. J., Donnelly, S. C., Hirani, N., Haslett, C., Strieter, R. M., Dark, J. H., and Corris, P. A. (2001) 'Elevated levels of interleukin-8 in donor lungs is associated with early graft failure after lung transplantation'. American Journal of Respiratory and Critical Care Medic, 163 (1):259-265. [Details]
Abe R., Donnelly, S. C., Peng, T., Bucala, R., and Metz, C. N. (2001) 'Peripheral blood fibrocytes: differentiation pathway and migration to wound sites'. Immunology, 166 (12):7556-7562. [Details]
Hirani, N., Antonicelli, F., Strieter, R. M., Wiesener, M. S., Ratcliffe, P. J., Haslett, C., Donnelly, S. C. (2001) 'The regulation of interleukin-8 by hypoxia in human macrophages--a potential role in the pathogenesis of the acute respiratory distress syndrome (ARDS)'. Molecular Medicine, 7 (10):685-697. [Details]
Sethi T, Rintoul RC, Moore SM, MacKinnon AC, Salter D, Choo C, Chilvers ER, Dransfield I, Donnelly SC, Strieter R, Haslett C. (1999) 'Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo'. Nat Medicine, 5 :662-668. [Details]
Fisher AJ, Donnelly SC, Hirani N, Burdick MD, Strieter RM, Dark JH, Corris PA. (1999) 'Enhanced pulmonary inflammation in organ donors following fatal non-traumatic brain injury'. Lancet, 353 :1412-1413. [Details]
Rossi, A. G., Haslett, C., Hirani, N., Greening, A. P., Rahman, I., Metz, C. N., Bucala, R., and Donnelly, S. C. (1998) 'Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma'. Clinical Investigation, 101 (12):2869-2874. [Details]
Rossi AG, Haslett C, Metz CN, Rahman I, Bucala R, Donnelly SC. (1998) 'Eosinophils are a source of macrophage migration inhibitory factor (MIF) ' potential role in asthma'. Journal of Clinical Investigation, 101 :2869-2874. [Details]
Donnelly, S. C., Haslett, C., Reid, P. T., Grant, I. S., Wallace, W. A., Metz, C. N., Bruce, L. J., and Bucala R. (1997) 'Regulatory role for macrophage migration inhibitory factor in acute respiratory distresssyndrome'. Nat Medicine, 3 (3):320-323. [Details]
Donnelly, S. C., Strieter, R. M., Reid, P. T., Kunkel, S. L., Burdick, M. D., Armstrong, I., Mackenzie, A., and Haslett, C. (1996) 'The association between mortality rates and decreased concentrations of interleukin-10 and interleukin-1 receptor antagonist in the lung fluids of patients with the adult respiratory distress syndrome'. Annals of International Medicine, 125 (3):191-196. [Details]
Donnelly SC, Strieter RM, Reid PT, Kunkel SL, Burdick MD, Armstrong I, McKenzie, A, Haslett C. (1996) 'Prognostic significance of Interleukin-10 (IL-10) and IL-1 receptor antagonist (IL-Ira), in broncho-alveolar lavage fluid from patients with the adult respiratory distress syndrome (ARDS)'. Annals of Internal Medicine, 125 :191-196. [Details]
Donnelly, S. C., Haslett, C., Dransfield, I., Robertson, C. E., Carter, D. C., Ross, J. A. , Grant, I. S. , Tedder, T. F. (1994) 'Role of selectins in development of adult respiratory distress syndrome'. Lancet, 344 (8917):215-219. [Details]
Donnelly, S. C., Strieter, R. M., Kunkel, S. L., Walz, A., Robertson, C. R., Carter, D. C., Grant, I. S., Pollok, A. J., and Haslett, C. (1993) 'Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups'. Lancet, 341 (8846):643-647. [Details]
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Other Journals:

Naji, N.A., Connor, C.M., Donnelly, S.C. McDonnell, T.J. (2006) 'Effectiveness of pulmonary rehabilitation in restrictive lung disease' j Cardiopulm Rehabil . [Details]

Conference Publications:

Adamali HI, Baugh J, Fingerle-Rowson G, McLoughlin P, Donnelly SC (2008) Enzymatic actvity of macrophage inhibitory factor (MIF) regulates growth of pseudomonas aeruginosa (Pa): implications for therapeutic interventions in cystic fibrosis American Thoracic Society International Conference [Details]

Phelan, D, Watson, CJ, Donnelly, S, Ledwidge, M, Baugh, J, Mcdonald, K, (2007) EUR J HEART FAIL Transforming growth factor beta induces collagen type I and alpha smooth muscle actin production in human cardiac fibroblasts , pp.101-101 [Details]

Watson, CJ, Phelan, DMJ, Ledwidge, M, Donnelly, S, Mcdonald, K, Baugh, J, (2007) EUR J HEART FAIL Increased MMP2 activity following treatment of cardiac fibroblast with Angiotensin II, Alclosterone, Endothelin-1 and TGF beta , pp.101-101 [Details]

Byrne, A., Li, L., Gantier, M., Donnelly, S.C. Baugh, J.A. (2006) Hypoxia-Induced Fibroroliferation is Rho Dependent and Augmented by Macrophage Migration Inhibitory Factor (MIF) American Thoracic Society [Details]

Martos, R., Baugh, J., Ledwidge, M., O'Loughlin, C., Conlon, C., Donnelly, S. McDonald, K. (2006) Elevated plasma markers of matrix metalloproteinases type 2 and 9 are independent predictors of diastolic heart failure Heart Failure Congress [Details]

Kettunen, M., Brennan, L., Govender, P., Newsholme, P., Baugh, J.A. Donnelly S.C. (2006) 1H NMR Analysis of BAL Fluid as a Potential Prognostic Tool in Sarcoidosis American Thoracic Society [Details]

Li, L., O'Reilly, KMA., Buckley, A., Byrne, A.B., McLaughlin, A.M., Kettunen, M.P, Govender, P., Baugh, J.A., Donnelly, S.C. (2006) Sarcoidosis Bronchoalveolar Lavage (BAL) Fluid Induces the Differentiation of Normal Human Primary Lung Fibroblasts into Myofibroblasts American Thoracic Society [Details]
Li, L., Byrne, A., O'Reilly, K.M.A., Donnelly S.C. Baugh, J.A. (2006) Macrophage Migration Inhibitory Factory (MFI) is an early growth response-1 (EGR-1) target gene in TGFb activated human lung fibroblasts American Thoracic Society [Details]
Byrne, A., Li, L., Gantier, M., Buckley, A., O'Reilly, K., Donnelly, S.C. Baugh, J.A. (2006) Macrophage Migration Inhibitory Factor (MIF): A Hypoxia Regulated Mediator of Pulmonary Fibrosis Hypoxia and Development, Physiology and Disease (Keystone) [Details]
Byrne, A., Li, L., Gantier, M., Donnelly, S.C. Baugh, J.A. (2006) Hypoxia-Induced Fibroroliferation is Rho Dependent and Augmented by Macrophage Migration Inhibitory Factor (MIF) American Thoracic Society [Details]
Kettunen, M., Brennan, L., Govender, P., Newsholme, P., Baugh, J.A. Donnelly S.C. (2006) 1H NMR Analysis of BAL Fluid as a Potential Prognostic Tool in Sarcoidosis American Thoracic Society University of New Mexico, Albuquerque, [Details]
Li, L., O'Reilly, KMA., Buckley, A., Byrne, A.B., McLaughlin, A.M., Kettunen, M.P, Govender, P., Baugh, J.A., Donnelly, S.C. (2006) Sarcoidosis Bronchoalveolar Lavage (BAL) Fluid Induces the Differentiation of Normal Human Primary Lung Fibroblasts into Myofibroblasts American Thoracic Society [Details]
Martos, R., Baugh, J., Ledwidge, M., O'Loughlin, C., Donnelly, S. McDonald, K. (2005) Diastolic Heart failure is associated with elevated serum markers of collagen turnover Irish Cardiac Society [Details]
Martos, R., Baugh, J., Ledwidge, M., Patle, A., O'Loughlin, C., Donnelly, S. McDonald, K. (2005) Brain natriuretic peptide levels correlate with indices of diastolic function and serum markers of increased collagen turnover Irish Cardiac Society [Details]
Martos, R., Baugh, J., Ledwidge, M., O'Loughlin, C., Donnelly, S. McDonald, K. (2005) Diastolic Heart failure is associated with elevated serum markers of collagen turnover Heart Failure Congress [Details]
Martos, R., Baugh, J., Ledwidge, M., O'Loughlin, C., Donnelly, S. McDonald, K. (2005) Diastolic Heart failure is associated with elevated serum markers of collagen turnover World Congress of Cardiology [Details]
Li, L., Byrne, A., O'Reilly, K.M.A., Donnelly S.C. Baugh, J.A. (2006) Macrophage Migration Inhibitory Factory (MFI) is an early growth response-1 (EGR-1) target gene in TGFb activated human lung fibroblasts American Thoracic Society [Details]
Byrne, A., Li, L., Gantier, M., Buckley, A., O'Reilly, K., Donnelly, S.C. Baugh, J.A. (2006) Macrophage Migration Inhibitory Factor (MIF): A Hypoxia Regulated Mediator of Pulmonary Fibrosis Hypoxia and Development, Physiology and Disease (Keystone) [Details]
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Abstract

Keane MP, Donnelly SC, Belperio JA, Goodman R, Burdick MD, Strieter RM (2002) IL-8 correlates with BALF angiogenic activity and pro-collagen levels in ARDS. Abstract [Details]