Professor Alan Baird

Research

Professor Alan Baird BSc, Ml BIOL, PhD.

Books:

Brayden, D. J. & Baird, A. W. (2004). Adv. Drug Del. Rev. (2004) Commentary: apical membrane receptors on intestinal M cells: potential targets for vaccine delivery. [Details]

Brayden, DJ & Baird, A.W. (2006) Current Opinion in Pharmacology: New Technologies. New York: Elsevier.

[Details]

Brayden, D. J. & Baird, A. W. (2004) Advanced Drug Delivery Reviews. Theme Issue. Pathogens and the intestine: mechanisms and exploitation. London: Elsevier. [Details]

Book Chapters:

Brayden, D.J., Oudot, E. & Baird, A.W. (2010) 'Drug delivery systems in domestic animal species' In: Lees, P., Cunningham, F., Elliot, J (eds). Handbook in Experimental Pharmacology. New York: Springer.

[Details]

Baird AW, Prosser E (1998) 'Cell culture models for polarised epithelial monolayers' In: Clynes M (eds). Animal Cell Culture Techniques. Heidelberg: Springer. [Details]

Peer Reviewed Journals:

Medani, M., Collins, D., Docherty, N.G., Baird, A.W., O'Connell, P.R., Winter, D.C. (2011) 'Emerging role of hydrogen sulfide in colonic physiology and pathophysiology'. Inflammatory bowel diseases, 17 (7):1620-1625. [DOI] [Details]

Rogers, A.C., Hanly, A.M., Collins, D., Baird, A.W., Winter, D.C. (2011) 'Review Article: Loss of the Calcium-Sensing Receptor in Colonic Epithelium is a Key Event in the Pathogenesis of Colon Cancer'. Cancer, . [DOI] [Details]

Walsh, E.G., Maher, S., Devocelle, M., O'Brien, P.J., Baird, A.W., Brayden, DJ. (2011) 'High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs'. Peptides, 32 (8):1764-1773.

[DOI] [Details]

Collins, D., Winter, D.C., Hogan, A.M., Schirmer, L., Baird, A.W., Stewart, G.S. (2010) 'Differential protein abundance and function of UT-B urea transporters in human colon'. The Journal of physiology, 298 :345-351. [DOI] [Details]

Morrissey, N.K., Bellenger, C.R., Ryan, M.T., Baird, A.W. (2010) 'Cyclooxygenase-2 mRNA expression in equine nonglandular and glandular gastric mucosal biopsy specimens obtained before and after induction of gastric ulceration via intermittent feed deprivation'. Veterinary Research, 71 (11):1312-1320. [DOI] [Details]

Brayden DJ, Oudot EJ, Baird AW (2010) 'Drug delivery systems in domestic animal species'. Handbook of experimental pharmacology, (199):79-112. [DOI] [Details]

Matlawska-Wasowska, K,Finn, R,Mustel, A,O'Byrne, CP,Baird, AW,Coffey, ET,Boyd, A (2010) 'The Vibrio parahaemolyticus Type III Secretion Systems manipulate host cell MAPK for critical steps in pathogenesis'. BMC microbiology, 10 . [DOI] [Details]
Morrissey, NK,Bellenger, CR,Ryan, MT,Baird, AW (2010) 'Cyclooxygenase-2 mRNA expression in equine nonglandular and glandular gastric mucosal biopsy specimens obtained before and after induction of gastric ulceration via intermittent feed deprivation'. American Journal of Veterinary Research, 71 :1312-1320. [Details]
Hogan AM, Collins D, Baird AW, Winter DC. (2009) 'Estrogen and gastrointestinal malignancy'. Molecular and Cellular Endocrinology, 307 (1-2):19-24. [Details]
Ryan, M. T.,Baird, A. W.,Mulholland, C. W.,Irwin, J. A. (2009) 'Practical classes: a platform for deep learning? Overall context in the first-year veterinary curriculum'. J Vet Med Educ, 36 (22):180-5180. [Details]
Nemeth, E.,Baird, A. W.,O'Farrelly, C. (2009) 'Microanatomy of the liver immune system'. Semin Immunopathol, 31 (33):333-43333. [Details]
Maher, S.,Kennelly, R.,Bzik, V. A.,Baird, A. W.,Wang, X.,Winter, D.,Brayden, D. J. (2009) 'Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae'. Eur J Pharm Sci, 38 (44):291-300291. [Details]
Collins D, Hogan AM, Skelly MM, Baird AW, Winter DC (2009) 'Cyclic AMP-mediated chloride secretion is induced by prostaglandin F2alpha in human isolated colon'. British journal of pharmacology, 158 (7):1771-1776. [DOI] [Details]
Hogan AM, Collins D, Baird AW, Winter DC. (2009) 'Estrogen and its role in gastrointestinal health and disease'. International Journal of Colorectal Disease, 24 (12):1367-1375. [Details]
Hogan AM, Collins D, Baird AW, Winter DC (2009) 'Estrogen and its role in gastrointestinal health and disease'. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 24 (12):1367-1375. [DOI] [Details]
Baird, AW,Skelly, MM,O'Donoghue, DP,Barrett, KE,Keely, SJ (2008) 'Bradykinin regulates human colonic ion transport in vitro'. British Journal of Pharmacology, 155 :558-566. [DOI] [Details]
Cox, AB,Rawlinson, LA,Baird, AW,Bzik, V,Brayden, DJ (2008) 'In vitro interactions between the oral absorption promoter, sodium caprate (C-10) and S-Typhimurium in rat intestinal ileal mucosae'. Pharm Res, 25 :114-122. [DOI] [Details]
O'Brien, LM,Fitzpatrick, E,Baird, AW,Campion, DP (2008) 'Eosinophil-nerve interactions and neuronal plasticity in rat gut associated lymphoid tissue (GALT) in response to enteric parasitism'. Journal of Neuroimmunology, 197 :1-9. [DOI] [Details]
Morrissey, NK,Bellenger, CR,Baird, AW (2008) 'Bradykinin stimulates prostaglandin E-2 production and cyclooxygenase activity in equine nonglandular and glandular gastric mucosa in vitro'. VET J, 40 :332-336. [DOI] [Details]
Fitzgerald, D.C., Meade, K.G., McEvoy, A.N., Lillis, L., Murphy, E.P., Machugh, D.E., Baird, A.W. (2007) 'Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells'. Veterinary Immunology and Immunopathology, 116 (1-2):59-68. [Details]
Collins, CB,McGrath, J,Baird, AW,Campion, DP (2007) 'Effect of mast cell degranulation on chicken ileal ion transport in vitro'. POULTRY SCI, 86 :843-849. [Details]
Deaton, CM,Deaton, L,Jose-Cunilleras, E,Vincent, TL,Baird, AW,Dacre, K,Marlin, DJ (2007) 'Early onset airway obstruction in response to organic dust in the horse'. Journal of Applied Physiology, 102 :1071-1077. [DOI] [Details]
Soni, J; Baird, AW; O'Brien, LM; McElroy, M; Callanan, JJ; Bassett, HF; Campion, D; Brayden, DJ; (2006) 'Rat, ovine and bovine Peyer's patches mounted in horizontal diffusion chambers display sampling function'. Journal of Controlled Release, 115 (1):68-77. [Details]
Canny, G.,Drudy, D.,Macmathuna, P.,O'Farrelly, C.,Baird, A. W. (2006) 'Toxigenic C. difficile induced inflammatory marker expression by human intestinal epithelial cells is asymmetrical'. Life Sci, 78 (9):920-5. [Details]
Brayden DJ, Soni J, Baird AW, O'Brien LM, McElroy M, Callanan JJ, Bassett HF, Campion D, (2006) 'Rat, ovine and bovine Peyer's patches mounted in horizontal diffusion chambers display sampling function'. Journal of controlled release : official journal of the Controlled Release Society, 115 (1):68-77. [DOI] [Details]
Canny, G., Drudy, D., Macmathuna, P., O'Farrelly, C., Baird, A.W. (2006) 'Toxigenic C. difficile induced inflammatory marker expression by human intestinal epithelial cells is asymmetrical'. LIFE SCIENCES, 78 (9):920-925. [Details]
Quinn, T., O'Mahony, R., Baird, A.W., Drudy, D., Whyte, P. & Fanning, S. (2006) 'Multi-drug resistance in Salmonella enterica: efflux mechanisms and their relationships with the development of chromosomal resistance gene clusters'. CURRENT DRUG TARGETS, 7 :849-860. [Details]
Brayden, D.J. and Baird, A.W. (2006) 'Pharmacology applied: delivering the goods'. Current Opinion in Pharmacology, 6 (5):491-493. [Details]
Soni, J,Baird, AW,O'Brien, LM,McElroy, M,Callanan, JJ,Bassett, HF,Campion, D,Brayden, DJ (2006) 'Rat, ovine and bovine Peyer's patches mounted in horizontal diffusion chambers display sampling function'. Journal of controlled release : official journal of the Controlled Release Society, 115 :68-77. [DOI] [Details]
Quinn, T,Feighery, R,Baird, AW (2006) 'Role of Rho-kinase in guinea-pig gallbladder smooth muscle contraction'. European Journal of Pharmacology, 534 :210-217. [DOI] [Details]
Quinn, T; O'Mahony, R; Baird, AW; Drudy, D; Whyte, P; Fanning, S; (2006) 'Multi-drug resistance in Salmonella enterica: Efflux mechanisms and their relationships with the development of chromosomal resistance gene clusters'. Current Drug Targets, 7 (7):849-860. [Details]
Baird AW, Brayden DJ, (2004) 'Apical membrane receptors on intestinal M cells: potential targets for vaccine delivery'. ADVANCED DRUG DELIVERY REVIEWS, 56 (6):721-726. [DOI] [Details]
Ryan MT, Irwin JA, Bannon FJ, Mulholland CW, Baird AW, (2004) 'Observations of veterinary medicine students' approaches to study in pre-clinical years'. Journal of Veterinary Medical Education, 31 (3):242-254. [Details]
Brayden DJ, Baird AW, Campion DP, O'Brien L, (2004) 'Oral delivery of pathogens from the intestine to the nervous system'. Journal of Drug Targeting, 12 (2):71-78. [DOI] [Details]
Ryan M.T., Irwin J.A., Bannon F.J., Mulholland C.W., Baird A.W. (2004) 'Observations of veterinary medicine students' approaches to study in pre-clinical years'. 31 Veterinary Medical Education (3):242-254. [Details]
Brayden, D. J. & Baird, A. W. (2004) 'Preface. Pathogen invasion across the intestine: mechanisms and potential exploitation'. Advanced Drugs Delivery Review, 56 (6):717-719. [Details]
Irwin, Jane; Baird, Alan W. (2004) 'Extremophiles and their application to veterinary medicine'. IRISH VETERINARY JOURNAL, 57 (6):348-354. [Details]
Feighery, LM; Keely, S; Smyth, A; Gilchrist, M.D.; Baird, AW; O'Connor, WT; Brayden, DJ; (2004) 'Demonstration of compromised ileal structure and function following severe acute trauma to the left forebrain in the isoflourane anaesthetized rat'. Molecular Biology of the Cell, 15 (NA):67-67. [Details]
Feighery, LM; Keely, S; Smyth, A; Gilchrist, M; Baird, AW; O'Connor, WT; Brayden, DJ; (2004) 'Demonstration of compromised ileal structure and function following severe acute trauma to the left forebrain in the isoflourane anaesthetized rat'. Molecular Biology of the Cell, 15 (NA):67-67. [Details]
Murphy, JEJ; McBean, GJ; Guiry, PJ; McCormack, P; Baird, AW; Keenan, AK; (2002) 'In vitro effects of (+/-)-4-methylthioamphetamine, (+/-)-4-methylthiomethamphetamine and (+/-)-MDMA on vascular responses to noradrenaline and phenylephrine'. British Journal of Pharmacology, 136 (NA). [Details]
Murphy, JEJ; Flynn, JJ; Cannon, DM; Guiry, PJ; McCormack, P; Baird, AW; McBean, GJ; Keenan, AK; (2002) 'In vitro neuronal and vascular responses to 5-hydroxytryptamine: modulation by 4-methylthioamphetamine, 4-methylthiomethamphetamine and 3,4-methylenedioxymethamphetamine'. European Journal of Pharmacology, 444 (1-2):61-67. [Details]
Murphy JEJ, Flynn J, Cannon DM, Guiry PJ, McCormack P, Baird AW, McBean GJ, Keenan AK (2002) 'In vitro neuronal and vascular responses to 5-HT: modulation by 4-MTA, 4-MTMA and MDMA'. European Journal of Pharmacology, 444 :61-67. [Details]
Murphy, JEJ; Cannon, DM; Guiry, P; McCormack, P; Baird, AW; McBean, GJ; Keenan, AK; (2001) 'A comparison of the in vitro effects of (+/-)-4-methylthioamphetamine and (+/-)-MDMA on 5-HT re-uptake in the brain and on vascular responses to 5-HT'. British Journal of Pharmacology, 134 (NA). [Details]
Baird AW, Brayden DJ, (2001) 'Microparticle vaccine approaches to stimulate mucosal immunisation'. Microbes and Infection, 3 (10):867-876. [Details]
Goh, J.,Baird, A. W.,O'Keane, C.,Watson, R. W.,Cottell, D.,Bernasconi, G.,Petasis, N. A.,Godson, C.,Brady, H. R.,MacMathuna, P. (2001) 'Lipoxin A(4) and aspirin-triggered 15-epi-lipoxin A(4) antagonize TNF-alpha-stimulated neutrophil-enterocyte interactions in vitro and attenuate TNF-alpha-induced chemokine release and colonocyte apoptosis in human intestinal mucosa ex vivo'. J Immunol, 167 (5):2772-80. [Details]
Irwin, J.A., Ryan, J.P., Leonard, M. Carrington, S.D., Baird, A.W. (2001) 'Mucin-degrading glycosidase activity in Peyer's patches'. Biochemical Society Transactions, 29 (5). [Details]
Brankin B., Canny G. & Baird A. (2001) 'MIP-1 production by brain endothelial cells'. Irish Journal of Medical Science, 170 (1). [Details]
Cannon DM, Keenan AK, Guiry PJ, Buon C, Baird AW, McBean GJ (2001) 'In vitro neuronal and vascular responses to 5-HT in rats chronically exposed to MDMA'. British Journal of Pharmacology, 134 :1455-1460. [Details]
Brayden, D. and Baird, A.W. (2001) 'Microparticle vaccine approachesto stimulate mucosal immunisation'. Microbes and Infection, 3 :867-876. [Details]
Baird, AW; Moriarty, D; Guiry, P; McBean, GJ; Keenan, AK; (2001) '(+/-)-3,4 methylenedioxymethamphetamine (MDMA) stimulates electrogenic ion transport in rat colonic mucosa in vitro'. British Journal of Pharmacology, 134 (NA). [Details]
Leonard, M., Creed, E., Brayden, D. and Baird, A.W. (2000) 'Iontophoresis-enhanced absorptive flux of polar molecules across intestinal tissue in vitro'. Pharmaceutical Research, 17 (4):476-478. [Details]
Moriarty, DV; O'Riordan, A; O'Donoghue, DP; Hyland, J; Sheahan, K; Baird, AW; (2000) 'Substance P release and modulation of human colonic ion transport: Alterations during IBD'. Gastroenterology, 118 (4):1105-1105. [Details]
McCole, D.F., Doherty, M.L., Baird, A.W., Davis, W.C., McGill, K. and Torgerson, P.R. (1999) 'T cell subset involvement in immune responses to Fasciola hepatica infection in cattle'. Parasite Immunology, 21 :1-8. [Details]
McCole, D. F., Doherty, M. L., Baird, A. W., Davis, W. C., McGill, K. and Torgerson, P. R. (1998) 'Concanavalin A-stimulated proliferation of T cell subset-depleted lymphocyte populations isolated from Fasciola hepatica-infected cattle'. Veterinary Immunology and Immunopathology, 66 :289-300. [Details]
McCole, D.F., Doherty, M.L., Torgerson, P.R and Baird, A.W. (1998) 'Local Immune Responses in Colon from Cattle infected with Fasciola hepatica'. International Journal of Parasitology, 28 :1733-1737. [Details]
Brayden, D.J., Moriarty, D. and Baird, A.W. (1998) 'A novel in vitro electrophysiological bioassay for transport of loperamide across intestinal epithelia'. Pharmaceutical Research, 14 (7):942-945. [Details]
Moriarty, D; Ettarh, R; Sheahan, K; Hyland, J; O'Donoghue, DP; Baird, AW; (1998) 'Structural associations between mast cells and enteric nerves in normal and inflamed human colon'. Gastroenterology, 114 (4):400-400. [Details]
TAYLOR, CT,BAIRD, AW (1995) 'BERBERINE INHIBITION OF ELECTROGENIC ION-TRANSPORT IN RAT COLON'. British Journal of Pharmacology, 116 :2667-2672. [Details]
KEELY, SJ,STACK, WA,ODONOGHUE, DP,BAIRD, AW (1995) 'REGULATION OF ION-TRANSPORT BY HISTAMINE IN HUMAN COLON'. European Journal of Pharmacology, 279 :203-209. [Details]
STACK, WA,KEELY, SJ,ODONOGHUE, DP,BAIRD, AW (1995) 'IMMUNE REGULATION OF HUMAN COLONIC ELECTROLYTE TRANSPORT IN-VITRO'. Gut, 36 :395-400. [Details]
O'Malley, K.E., Farrell, C.B., OBoyle, K.M. & Baird, A.W. (1995) 'Cholinergic activation of chloride secretion in rat colonic epithelia'. European Journal of Pharmacology, 275 :83-89. [Details]
BAIRD, AW (1994) 'REGULATION OF CHLORIDE SECRETION IN MAMMALIAN COLON'. IRISH J MED SCI, 163 :277-281. [Details]
Brayden, D.J. and Baird, A.W. (1994) 'A distinctive eletrophysiological signature from the Peyer's patch of the rabbit'. British Journal of Clinical Pharmacology, 113 :593-599. [Details]
O'Malley, K. E.; Sloan, T.; Joyce, P., and Baird, A. W. (1993) 'Type 1 hypersensitivity reactions in intestinal mucosae from rats infected with Fasciola hepatica'. Parasite Immunology, 15 :449-453. [Details]
BAIRD, AW,OMALLEY, KE (1993) 'EPITHELIAL ION-TRANSPORT - POSSIBLE CONTRIBUTION TO PARASITE EXPULSION'. Parasitology Today, 9 :141-143. [Details]
OMALLEY, KE,SLOAN, T,JOYCE, P,BAIRD, AW (1993) 'TYPE-I HYPERSENSITIVITY REACTIONS IN INTESTINAL MUCOSAE FROM RATS INFECTED WITH FASCIOLA-HEPATICA'. Immunology, 15 :449-453. [Details]
Hogan, AM,Collins, D,Sheehan, K,Zierau, O,Baird, AW,Winter, DC (2010) 'Rapid effects of phytoestrogens on human colonic smooth muscle are mediated by oestrogen receptor beta'. Cell, 320 :106-110. [DOI] [Details]
Collins, D., Winter, D.C., Hogan, A.M., Schirmer, L., Baird, A.W. and Stewart, G.S. (2010) 'Differential protein abundance and function of UT-B urea transporters in human colon'. American Journal of Physiology Gastrointestinal Physiology, 298 :G345-G351. [DOI] [Details]
Morrissey, P.E.W., Folan, M.A., Baird A.W., Irwin, J.A. (2010) 'Effect of a partially digested whey concentrate on Salmonella enterica serotype Typhimurium adhesion to Caco-2 cells'. Food Control, 21 (8):1113-1120. [DOI] [Details]
Irwin JA, Ryan MT, Baird AW, Mulholland CW, (2009) 'Practical classes: a platform for deep learning? Overall context in the first-year veterinary curriculum'. Journal of Veterinary Medical Education, 2 (NA):180-185. [DOI] [Details]
Winter DC, Hogan AM, Gallagher TK, Rory K, Baird AW, (2009) 'Gastric applications of electrical field stimulation'. Surgical laparoscopy, endoscopy & percutaneous techniques, 2 (NA):85-89. [DOI] [Details]
Winter DC, Hogan AM, Collins D, Baird AW, (2009) 'Estrogen and gastrointestinal malignancy'. Molecular and Cellular Endocrinology, 1-2 (NA):19-24. [DOI] [Details]
Hogan, AM,Kennelly, R,Collins, D,Baird, AW,Winter, DC (2009) 'Oestrogen inhibits human colonic motility by a non-genomic cell membrane receptor-dependent mechanism'. British Journal of Surgery, 96 :817-822. [DOI] [Details]
Maher, S,Kennelly, R,Bzik, VA,Baird, AW,Wang, XX,Winter, D,Brayden, DJ (2009) 'Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae'. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 38 :291-300. [DOI] [Details]
Ryan MT, Baird AW, Mulholland CW, Irwin JA, (2009) 'Practical classes: a platform for deep learning? Overall context in the first-year veterinary curriculum'. Journal of Veterinary Medical Education, 36 (2):180-185. [DOI] [Details]
Collins, D,Hogan, AM,Skelly, MM,Baird, AW,Winter, DC (2009) 'Cyclic AMP-mediated chloride secretion is induced by prostaglandin F-2 alpha in human isolated colon'. British Journal of Pharmacology, 158 :1771-1776. [DOI] [Details]
Brayden DJ, Maher S, Kennelly R, Bzik VA, Baird AW, Wang X, Winter D, (2009) 'Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae'. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 38 (4):291-300. [DOI] [Details]
Winter DC, Gallagher TK, Baird AW, (2009) 'Constitutive basal and stimulated human small bowel contractility is enhanced in obesity'. Annals of surgical innovation and research, (NA). [DOI] [Details]
O'Farrelly C, Nemeth E, Baird AW, (2009) 'Microanatomy of the liver immune system'. Seminars in immunopathology, . [DOI] [Details]
Cox, A. B., Rawlinson, L. A., Baird, A. W., Bzik, V., Brayden, D. J., (2008) 'In vitro interactions between the oral absorption promoter, sodium caprate (C-10) and S-Typhimurium in rat intestinal ileal mucosae'. Pharmaceutical Research, 25 (1):114-122. [Details]
Brayden DJ, Feighery LM, Cochrane SW, Quinn T, Baird AW, O'Toole D, Owens SE, O'Donoghue D, Mrsny RJ, (2008) 'Myosin light chain kinase inhibition: correction of increased intestinal epithelial permeability in vitro'. Pharmaceutical Research, 25 (6):1377-1386. [DOI] [Details]
Brayden DJ, Cox AB, Rawlinson LA, Baird AW, Bzik V, (2008) 'In vitro interactions between the oral absorption promoter, sodium caprate (C(10)) and S. typhimurium in rat intestinal ileal mucosae'. Pharmaceutical Research, 25 (1):114-122. [DOI] [Details]
Brayden DJ, Feighery L, Smyth A, Keely S, Baird AW, O'Connor WT, Callanan JJ, (2008) 'Increased intestinal permeability in rats subjected to traumatic frontal lobe percussion brain injury'. The Journal of trauma, 64 (1):131-11. [DOI] [Details]
Nemeth, F., Hopkins, A. M., Baird, A. W., (2008) 'Neuroimmunology of the liver - Methodology in intact organs'. Journal of Neuroimmunology, 197 (2):171-171. [Details]
Campion DP, O'Brien LM, Fitzpatrick E, Baird AW, (2008) 'Eosinophil-nerve interactions and neuronal plasticity in rat gut associated lymphoid tissue (GALT) in response to enteric parasitism'. Journal of Neuroimmunology, 197 (1):1-9. [DOI] [Details]
Keely SJ, Baird AW, Skelly MM, O'Donoghue DP, Barrett KE, (2008) 'Bradykinin regulates human colonic ion transport in vitro'. British Journal of Pharmacology, 155 (4):558-566. [DOI] [Details]
Morrissey, N. K., Bellenger, C. R., Baird, A. W., (2008) 'Bradykinin stimulates prostaglandin E-2 production and cyclooxygenase activity in equine nonglandular and glandular gastric mucosa in vitro'. Equine Veterinary Journal, 40 (4):332-336. [Details]
O'Brien, L. M., Fitzpatrick, E., Baird, A. W., Campion, D. P., (2008) 'Eosinophil-nerve interactions and neuronal plasticity in rat gut associated lymphoid tissue (GALT) in response to enteric parasitism'. Immunology, 197 (1):1-9. [Details]
Bolan, T. M., Hayes, L., Sweeney, T., Callan, J. J., Baird, A. W., Keely, S., Crosby, T. F., (2008) 'The effects of cobalt and iodine supplementation of the pregnant ewe diet on immunoglobulin G, vitamin E, T-3 and T-4 levels in the progeny'. Animal, 2 (2):197-206. [Details]
Fitzgerald, D. C.,Meade, K. G.,McEvoy, A. N.,Lillis, L.,Murphy, E. P.,Machugh, D. E.,Baird, A. W. (2007) 'Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells'. Vet Immunol Immunopathol, 116 (1-2):59-68. [Details]
Deaton, CM, Deaton, L, Jose-Cunilleras, E, Vincent, TL, Baird, AW, Dacre, K, Marlin, DJ, (2007) 'Early onset airway obstruction in response to organic dust in the horse'. Journal of Applied Physics, 102 :1071-1077. [Details]
Brayden, D.J. & Baird, A.W. (2006) 'Pharmacology applied: delivering the goods'. Current Opinion in Pharmacology, 6 (5):491-493. [Details]
Baird, AW, Campion, DP, O'Brien, L, Brayden, DJ, (2004) 'Oral delivery of pathogens from the intestine to the nervous system'. Journal of Drug Targeting, 12 (2):71-78. [Details]
Quinn, T, Collins, C, Baird, AW, (2004) 'Mechanisms of neurokinin A- and substance P-induced contractions in rat detrusor smooth muscle in vitro'. Bju International, 94 (4):651-657. [Details]
O'Keeffe, C, Baird, AW, Nolan, N, Mccormick, PA, (2004) 'Cholestatic pruritus - the role of cutaneous mast cells and nerves'. Alimentary Pharmacology & Therapeutics, 19 (12):1293-1300. [Details]
Murphy, JEJ,Flynn, JJ,Cannon, DM,Guiry, PJ,McCormack, P,Baird, AW,McBean, GJ,Keenan, AK (2002) 'In vitro neuronal and vascular responses to 5-hydroxytryptamine: modulation by 4-methylthioamphetamine, 4-methylthiomethamphetamine and 3,4-methylenedioxymethamphetamine'. European Journal of Pharmacology, 444 (NA):61-67. [DOI] [Details]
Cannon, DM; Keenan, AK; Guiry, PJ; Buon, C; Baird, AW; McBean, GJ; (2001) 'In vitro neuronal and vascular responses to 5-HT in rats chronically exposed to MDMA'. British Journal of Pharmacology, 134 (7):1455-1460. [DOI] [Details]
OMALLEY, KE; SLOAN, T; JOYCE, P; BAIRD, AW; (1993) 'TYPE-I HYPERSENSITIVITY REACTIONS IN INTESTINAL MUCOSAE FROM RATS INFECTED WITH FASCIOLA-HEPATICA'. Parasite Immunology, 15 (8):449-453. [Details]
BAIRD, AW, OMALLEY, KE, (1993) 'EPITHELIAL ION-TRANSPORT - POSSIBLE CONTRIBUTION TO PARASITE EXPULSION'. Parasitology Today, 9 (4):141-143. [Details]
Baird AW, Margolius HS. (1989) 'Bradykinin stimulates electrogenic bicarbonate secretion by the guinea pig'. Journal of Pharmacology and Experimental Therapeutics, 248 :268-272. [Details]
Baird AW, Barclay WS, Blazer-Yost BL, Cuthbert AW. (1987) 'Affinity purified immunoglobulin G transfers immediate hypersensitivity to guinea'. Gastroenterology, 92 :635-642. [Details]
Cuthbert AW, Baird AW. (1987) 'Multiple mediators of type I hypersensitivity reactions in epithelia'. American Journal of Physiology, 252 :443-444. [Details]
Baird AW, Cuthbert AW, Pearce FL. (1985) 'Immediate hypersensitivity reactions in epithelia from rats infected with'. British Journal of Pharmacology, 85 :787-795. [Details]
Baird AW, Cuthbert AW. (1985) 'Changed sensitivity to antigen in a gut epithelium treated with bile salts'. British Journal of Pharmacology, 84 :653-656. [Details]
Baird AW, Coombs RR, McLaughlan P, Cuthbert AW. (1984) 'Immediate hypersensitivity reactions to cow milk proteins in isolated epithelium'. International Archives of Allergy and Applied Immunolog, 75 :255-263. [Details]
Pearce JB, Baird AW, Williamson EM, Evans FJ. (1983) 'Inhibition of histamine-induced acid secretion in rat isolated gastric mucosa by'. Journal of Pharmacy and Pharmacology, 81 :737-738. [Details]
Feighery, L., Smyth, A, Keely, S., Baird, A. W., O'Connor, W. T., Callanan, J. J., & Brayden, D. J. (2008) 'Increased intestinal permeability in rats subjected to traumatic frontal lobe percussion brain injury'. Journal of Trauma, Injury, Infection and Critical Care, 64 (1):131-137. [Details]
Feighery, L. M., Cochrane, S.W., Quinn, T., Baird, A. W., O'Toole, D., Owens, S-E., O'Donoghue, D., Mrsny, R. J. & Brayden, D. J. (2008) 'Myosin light chain kinase inhibition: attempts to correct increased intestinal epithelial permeability in vitro'. Pharmaceutical Research, . [Details]
Drudy, D., Harnedy, N., Fanning, S., O'Mahony, R., Baird, A. and Kyne, L. (2007) 'Isolation and characterisation of toxin A-negative, toxin B-positive C. difficile in Dublin, Ireland'. Clinical Microbiology and Infection, 13 :298-304. [Details]
Brayden, D.J. and Baird, A.W. (2006) 'Pharmacology applied: delivering the goods'. Current Opinion in Pharmacology, 6 (5):491-493. [Details]
Collins, C., Baird, A.W. and Campion, D. (2007) 'Effect of mast cell degranulation on chicken ileal ion transport in vitro'. Poultry Science, 86 (5):843-849. [Details]
Cox A.B., Rawlinson L.A., Baird A.W., Bzik V., Brayden D.J. (2007) 'In vitro Interactions Between the Oral Absorption Promoter, Sodium Caprate'. Pharmaceutical Research, . [Details]
Deaton C.M., Deaton L., Jose-Cunilleras E., Vincent T.L., Baird A.W., Dacre K., Marlin (2007) 'Early onset airway obstruction in response to organic dust in the horse'. Journal of Applied Physiology, 102 (3):1071-1077. [Details]
Soni, J; Baird, AW; O'Brien, LM; McElroy, M; Callanan, JJ; Bassett, HF; Campion, D; Brayden, DJ; (2006) 'Rat, ovine and bovine Peyer's patches mounted in horizontal diffusion chambers display sampling function'. Journal of Controlled Release, 115 (1):68-77. [Details]
Quinn, T; Molloy, M; Smyth, A; Baird, AW; (2004) 'Capacitative calcium entry in guinea pig gallbladder smooth muscle in vitro'. Life Sciences, 74 (13):1659-1669. [Details]
Brayden, DJ; Baird, AW; (2004) 'Apical membrane receptors on intestinal M cells: potential targets for vaccine delivery'. ADVANCED DRUG DELIVERY REVIEWS, 56 (6):721-726. [Details]
Irwin, JA; Baird, AW; (2004) 'Extremophiles and their application to veterinary medicine'. Irish Veterinary Journal, 57 (6):348-354. [Details]
Brayden, DJ; Baird, AW; (2004) 'Pathogen invasion across intestine: mechanisms and potential exploitation - Preface'. ADVANCED DRUG DELIVERY REVIEWS, 56 (6):717-719. [Details]
Feighery, LM; Quinn, TM; Baird, AW; Brayden, DJ; (2004) 'Pharmacological manipulation of tight junctions in rat colonic mucosa in vitro'. MOLECULAR BIOLOGY OF THE CELL, 15 (NA):67-67. [Details]
Ryan, MT; Irwin, JA; Bannon, FJ; Mulholland, CW; Baird, AW; (2004) 'Observations of veterinary medicine students' approaches to study in pre-clinical years'. Journal of Veterinary Medical Education, 31 (3):242-254. [Details]
Goode, T; O'Connor, T; Hopkins, A; Moriarty, D; O'Sullivan, GC; Collins, JK; O'Donoghue, D; Baird, AW; O'Connell, J; Shanahan, F; (2003) 'Neurokinin-1 receptor (NK-1R) expression is induced in human colonic epithelial cells by proinflammatory cytokines and mediates proliferation in response to substance P'. Journal of Cellular Physiology, 197 (1):30-41. [Details]
Gaines, S; James, TC; Folan, M; Baird, AW; O'Farrelly, C; (2003) 'A novel spectrofluorometric microassay for Streptococcus mutans adherence to hydroxylapatite'. Journal of Microbiological Methods, 54 (3):315-323. [Details]
Cochrane, SWJ; O'Donoghue, DP; Baird, AW; (2003) 'Monitoring M cell conversion in vitro: The role of lymphocyte epithelial cell contact'. Gut, 52 (NA):8-8. [Details]
Hopkins, AM; McDonnell, C; Breslin, NP; O'Morain, CA; Baird, AW; (2002) 'Omeprazole increases permeability across isolated rat gastric mucosa pre-treated with an acid secretagogue'. Journal of Pharmacy and Pharmacology, 54 (3):341-347. [Details]
Murphy, JEJ; McBean, GJ; Guiry, PJ; McCormack, P; Baird, AW; Keenan, AK; (2002) 'In vitro effects of (+/-)-4-methylthioamphetamine, (+/-)-4-methylthiomethamphetamine and (+/-)-MDMA on vascular responses to noradrenaline and phenylephrine'. British Journal of Pharmacology, 136 (NA). [Details]
O'Keeffe, C; Baird, AW; Nolan, N; McCormick, PA; (2002) 'Mast cell hyperplasia in chronic rejection after liver transplantation'. Liver Transplantation, 8 (1):50-57. [Details]
Forrest, AS; Quinn, T; Keenan, AK; Usher, C; Parsons, ME; Brayden, DJ; Baird, AW; (2002) 'Megacolon in the streptozotocin-treated diabetic rat'. British Journal of Pharmacology, 136 (NA). [Details]
Quinn, T; Molloy, M; Smith, A; Baird, AW; (2002) 'Capacitative calcium entry in guinea-pig gallbladder smooth muscle'. British Journal of Pharmacology, 136 (NA). [Details]
Cochrane, S; Quinn, T; O'Donoghue, DP; Baird, AW; Brayden, DJ; (2002) 'The effect of myosin light chain kinase inhibition on pharmacologically induced changes in paracellular intestinal epithelial permeability'. BRITISH JOURNAL OF PHARMACOLOGY, 136 (NA). [Details]
Byrne, D; Leonard, M; Mah, S; Lo, D; Baird, A; O'Mahony, D; Brayden, D; (2001) 'Differential expression of genes in a Peyer's Patch M cell co-culture model by TOGA (TM)'. British Journal of Pharmacology, 134 (NA). [Details]
Murphy, JEJ; Cannon, DM; Guiry, P; McCormack, P; Baird, AW; McBean, GJ; Keenan, AK; (2001) 'A comparison of the in vitro effects of (+/-)-4-methylthioamphetamine and (+/-)-MDMA on 5-HT re-uptake in the brain and on vascular responses to 5-HT'. British Journal of Pharmacology, 134 (NA). [Details]
Leonard, M; Brayden, DJ; Baird, AW; (2001) 'An in vitro intestinal cell culture model of M-cells displays a Th1 type cytokine profile'. British Journal of Pharmacology, 134 (NA). [Details]
Goh, J; Baird, AW; O'Keane, C; Watson, RWG; Cottell, D; Bernasconi, G; Petasis, NA; Godson, C; Brady, HR; MacMathuna, P; (2001) 'Lipoxin A(4) and aspirin-triggered 15-epi-lipoxin A(4) antagonize TNF-alpha-stimulated neutrophil-enterocyte interactions in vitro and attenuate TNF-alpha-induced chemokine release and colonocyte apoptosis in human intestinal mucosa ex vivo'. Immunology, 167 (5):2772-2780. [Details]
McCormack, G; O'Donoghue, D; Baird, A; (2001) 'In-vitro cyclosporin sensitivity of proliferating lymphocytes is predictive of in-vivo therapeutic response in ulcerative colitis'. Alimentary Pharmacology & Therapeutics, 15 (5):665-668. [Details]
McCormack, G; Moriarty, D; O'Donoghue, DP; McCormick, PA; Sheahan, K; Baird, AW; (2001) 'Tissue cytokine and chemokine expression in inflammatory bowel disease'. Inflammation Research, 50 (10):491-495. [Details]
Skelly, MM; O'Donoghue, DP; Baird, AW; (2001) 'Oxygen metabolites in immune-stimulated ion transport in rat colon: Modulation by taurine'. Digestion, 63 (2):124-129. [Details]
Drudy, D; O'Donoghue, DP; Baird, A; Fenelon, L; O'Farrelly, C; (2001) 'Flow cytometric analysis of Clostridium difficile adherence to human intestinal epithelial cells'. Journal of Medical Microbiology, 50 (6):526-534. [Details]
Moriarty, D; Goldhill, J; Selve, N; O'Donoghue, DP; Baird, AW; (2001) 'Human colonic anti-secretory activity of the potent NK1 antagonist, SR140333: assessment of potential anti-diarrhoeal activity in food allergy and inflammatory bowel disease'. British Journal of Pharmacology, 133 (8):1346-1354. [Details]
O'Riordan, AM; Quinn, T; Hyland, JM; O'Donoghue, DP; Baird, AW; (2001) 'Sources of calcium in neurokinin A-induced contractions of human colonic smooth muscle in vitro'. American Journal of Gastroenterology, 96 (11):3117-3121. [Details]
O'Riordan, AM; Quinn, T; Baird, AW; (2001) 'Role of prostaglandin E-2 and Ca2+ in bradykinin induced contractions of guinea-pig gallbladder in vitro'. European Journal of Pharmacology, 431 (2):245-252. [Details]
Brayden, DJ; Baird, AW; (2001) 'Microparticle vaccine approaches to stimulate mucosal immunisation'. Microbes and Infection, 3 (10):867-876. [Details]
Canny, GO; Drudy, D; Mac Mathuna, P; O'Farrelly, C; Baird, AW; (2001) 'Comparison of toxigenic and non toxigenic Clostridium difficile on T84 cell inflammatory phenotype'. Gastroenterology, 120 (5):326-326. [Details]
Moriarty, D; Selve, N; Baird, AW; Goldhill, J; (2001) 'Potent NK1 antagonism by SR-140333 reduces rat colonic secretory response to immunocyte activation'. American Journal of Physiology-Cell Physiology, 280 (4):852-858. [Details]
Leonard, M; Creed, E; Brayden, D; Baird, AW; (2000) 'Evaluation of the Caco-2 monolayer as a model epithelium for iontophoretic transport'. Pharmaceutical Research, 17 (10):1181-1188. [Details]
McCormack, GM; Moriarty, DV; Baird, AW; McCormick, PA; O'Donoghue, DP; (2000) 'Circulating cytokines with chemotactic activity are increased in newly diagnosed Inflammatory Bowel Disease'. Gastroenterology, 118 (4):1356-1357. [Details]
Moriarty, DV; O'Riordan, A; O'Donoghue, DP; Hyland, J; Sheahan, K; Baird, AW; (2000) 'Substance P release and modulation of human colonic ion transport: Alterations during IBD'. Gastroenterology, 118 (4):1105-1105. [Details]
Gullberg, E; Leonard, M; Karlsson, J; Hopkins, AM; Brayden, D; Baird, AW; Artursson, P; (2000) 'Expression of specific markers and particle transport in a new human intestinal M-cell model'. Biochemical and Biophysical Research Communications, 279 (3):808-813. [Details]
Leonard, M; Creed, E; Brayden, D; Baird, AW; (2000) 'Iontophoresis-enhanced absorptive flux of polar molecules across intestinal tissue in vitro'. Pharmaceutical Research, 17 (4):476-478. [Details]
Goh, J; Baird, AW; Watson, WR; Godson, C; O'Keane, C; Brady, HR; MacMathuna, P; (2000) 'Lipoxins attenuate TNF-A-induced apoptosis in human colonic mucosa'. Gastroenterology, 118 (4):806-806. [Details]
Maher, LJ; Skelly, MM; Godson, C; Brady, HR; Baird, AW; (1999) 'Lipoxin A(4) inhibits mast cell stimulation in rat colon in vitro'. Gastroenterology, 116 (4):905-905. [Details]
Hopkins, AM; O'Farrelly, C; O'Donoghue, DP; Moran, AP; Baird, AW; (1999) 'Apical ICAM-I polarization on intestinal epithelia: Implications for bacterial adherence'. Gut, 44 (NA):92-92. [Details]
McCormack, G; McCormick, PA; Hyland, J; Baird, A; O'Donoghue, D; (1999) 'Patient targeted therapy - The use of cyclosporin in the treatment of acute ulcerative colitis'. Gut, 44 (NA):37-37. [Details]
McKay, DM; Baird, AW; (1999) 'Cytokine regulation of epithelial permeability and ion transport'. Gut, 44 (2):283-289. [Details]
Taylor, CT; Winter, DC; Skelly, MM; O'Donoghue, DP; O'Sullivan, GC; Harvey, BJ; Baird, AW; (1999) 'Berberine inhibits ion transport in human colonic epithelia'. European Journal of Pharmacology, 368 (1):111-118. [Details]
Moriarty, DV; Hyland, JMP; O'Donoghue, DP; Baird, AW; (1999) 'Tachykinin induced ion transport responses in human colonic mucosa in vitro'. Gut, 44 (NA):102-102. [Details]
Winter, DC; Taylor, C; O'Sullivan, GC; Baird, AW; Harvey, BJ; (1999) 'Regulation of prostaglandin F2-alpha-induced secretion in human colon'. Gastroenterology, 116 (4):946-946. [Details]
Hopkins, AM; O'Farrelly, C; O'Donoghue, DP; Jordan, NJ; Westwick, J; Baird, AW; (1999) 'Chemokines and intestinal epithelia: Direct modulation of epithelial function?'. Gastroenterology, 116 (4):889-889. [Details]
Goode, T; Hopkins, A; Moriarty, D; O'Connell, J; O'Sullivan, GC; O'Donoghue, D; Collins, JK; Baird, AW; Shanahan, FLJ; (1999) 'Epithelial modulation by a local neuroimmune network of substance P and cytokines'. Gastroenterology, 116 (4):725-725. [Details]
McCormack, GM; McCormick, PA; Hyland, JMP; Baird, AW; O'Donoghue, DP; (1999) 'Patient targeted therapy - Use of cyclosporin in treatment of acute ulcerative colitis'. Gastroenterology, 116 (4):773-773. [Details]
Hopkins, AM; O'Farrelly, C; O'Donoghue, DP; Moran, AP; Baird, AW; (1999) 'Apical ICAM-1 polarization on intestinal epithelia: Implications for bacterial adherence'. Gastroenterology, 116 (4):889-889. [Details]
Moriarty, DV; Hyland, JMP; O'Donoghue, DP; Baird, AW; (1999) 'Tachykinin-induced ion transport responses in human colonic mucosa'. Gastroenterology, 116 (4):628-628. [Details]
McCole, DF; Doherty, ML; Torgerson, PR; Baird, AW; (1998) 'Local immune responses in colon from cattle infected with Fasciola hepatica'. International Journal for Parasitology, 28 (11):1733-1737. [Details]
McBride, S; Meleady, P; Baird, A; Dinsdale, D; Clynes, M; (1998) 'Human lung carcinoma cell line DLKP contains 3 distinct subpopulations with different growth and attachment properties'. Tumor Biology, 19 (2):88-103. [Details]
McCole, DF; Doherty, ML; Baird, AW; Torgerson, PR; (1998) 'Bovine T lymphocyte subpopulation responses in Fasciola hepatica infection'. Irish Veterinary Journal, 51 (3):133-133. [Details]
McCole, DF; Doherty, ML; Baird, AW; Torgerson, PR; (1998) 'T-lymphocyte subpopulation responses in cattle infected with Fasciola hepatica'. Gastroenterology, 114 (4):1299-1299. [Details]
Moriarty, D; Ettarh, R; Sheahan, K; Hyland, J; O'Donoghue, DP; Baird, AW; (1998) 'Structural associations between mast cells and enteric nerves in normal and inflamed human colon'. Gastroenterology, 114 (4):400-400. [Details]
Hopkins, AM; Myers, A; Moynagh, P; O'Donoghue, DP; Baird, AW; (1998) 'Electrophysiological parameters of human intestinal epithelial cells are differentially altered by exposure to lymphocyte-conditioned media'. Gastroenterology, 114 (4):378-378. [Details]
Terres, AM; Pajares, JM; Hopkins, AM; Murphy, A; Moran, A; Baird, AW; Kelleher, D; (1998) 'Helicobacter pylori disrupts epithelial barrier function in a process inhibited by protein kinase C activators'. Infection and Immunity, 66 (6):2943-2950. [Details]
Winter, DC; Taylor, CT; Skelly, MM; O'Donoghue, DP; O'Sullivan, GC; Baird, AW; Harvey, BJ; (1998) 'Berberine modulates human colonic secretion by blocking serosal membrane potassium channels'. Gastroenterology, 114 (4):433-433. [Details]
McCole, DF; Otti, B; Newsholme, P; Baird, AW; (1997) 'Complement activation of electrogenic ion transport in isolated rat colon'. Biochemical Pharmacology, 54 (10):1133-1137. [Details]
Taylor, CT; Murphy, A; Kelleher, D; Baird, AW; (1997) 'Changes in barrier function of a model intestinal epithelium by intraepithelial lymphocytes require new protein synthesis by epithelial cells'. Gut, 40 (5):634-640. [Details]
Skelly, MM; Stapleton, P; BouchierHayes, D; ODonoghue, DP; Baird, AW; (1997) 'Taurine inhibits immune stimulated ion transport in rat colon in vitro'. Gastroenterology, 112 (4):1094-1094. [Details]
Skelly, MM; ODonoghue, DP; Baird, AW; (1997) 'Prostaglandin E-2 primes human colonic mucosa for the prosecretory action of immunocyte activator fMLP and anti-IgE'. Gastroenterology, 112 (4):1094-1094. [Details]
McCole, DF; Doherty, ML; Torgerson, PR; Baird, AW; (1997) 'Cellular and ion transport responses in Fasciola hepatica sensitized bovine colon'. Gastroenterology, 112 (4):1037-1037. [Details]
Hopkins, AM; Maher, L; Masood, U; Baird, AW; (1997) 'Coordination of electrolyte and IgA secretion in isolated sheets of rat ileum'. Gastroenterology, 112 (4):999-999. [Details]
Terres, AM; Pajares, JM; Hopkins, A; Murphy, A; Baird, A; Kelleher, D; (1997) 'H-pylori induce increased permeability in T84 epithelial monolayers'. Gut, 41 (NA):23-23. [Details]
Skelly, MM; ODonoghue, DP; Baird, AW; (1997) 'Prostaglandin E-2 primes human colonic mucosa for the secretory action of the immunocyte activators fMLP and anti-IgE'. Gut, 41 (NA):2-2. [Details]
Maher, LJ; Hopkins, AM; Skelly, MM; ODonoghue, DP; Baird, AW; (1997) 'Complement stimulation of ion transport across human colonic mucosa in vitro'. Gut, 41 (NA):40-40. [Details]
Brayden, D; Moriarty, D; Baird, A; (1997) 'A novel in vitro electrophysiological bioassay for transport of loperamide across intestinal epithelia'. Pharmaceutical Research, 14 (7):942-945. [Details]
Maher, LJ; McCole, DF; Baird, AW; (1997) 'Synthetic complainant component C3a stimulates ion transport across rat colonic mucosa in vitro'. Gut, 41 (NA):190-190. [Details]
McCole, DF; Dunne, JF; Newsholme, PN; Baird, AW; (1996) 'Intestinal ion transport activation by human complement'. Gastroenterology, 110 (4):346-346. [Details]
Skelly, MM; ODonoghue, DP; Baird, AW; (1996) 'Hydrogen peroxide causes electrogenic chloride secretion in human colon in vitro'. Gastroenterology, 110 (4):361-361. [Details]
Skelly, MM; Keely, SJ; ODonoghue, DP; Baird, AW; (1996) 'Secretory responses to bradykinin in human colon are mediated by B2 receptors and endogenous peptidases but not by immune cells'. Gastroenterology, 110 (4):361-361. [Details]
Taylor, CT; Murphy, A; Kelleher, D; Baird, AW; (1996) 'Regulation of intestinal epithelial barrier function by intraepithelial lymphocytes'. Gastroenterology, 110 (4):1027-1027. [Details]
Taylor, CT; Baird, AW; (1996) 'Berberine inhibition of epithelial ion transport in human tissue'. Gastroenterology, 110 (4):1027-1027. [Details]
KEELY, SJ; STACK, WA; ODONOGHUE, DP; BAIRD, AW; (1995) 'REGULATION OF ION-TRANSPORT BY HISTAMINE IN HUMAN COLON'. European Journal of Pharmacology, 279 (2-3):203-209. [Details]
STACK, WA; KEELY, SJ; ODONOGHUE, DP; BAIRD, AW; (1995) 'IMMUNE REGULATION OF HUMAN COLONIC ELECTROLYTE TRANSPORT IN-VITRO'. Gut, 36 (3):395-400. [Details]
TAYLOR, CT; BAIRD, AW; (1995) 'BERBERINE INHIBITION OF ELECTROGENIC ION-TRANSPORT IN RAT COLON'. British Journal of Pharmacology, 116 (6):2667-2672. [Details]
TAYLOR, CT; MORIARTY, DV; SKELLY, MM; ODONOGHUE, DP; BAIRD, AW; (1995) 'ANTI-SECRETORY EFFECTS OF BERBERINE IN HUMAN COLONIC EPITHELIUM'. Gastroenterology, 108 (4):331-331. [Details]
TAYLOR, CT; MURPHY, A; KELLEHER, D; BAIRD, AW; (1995) 'REGULATION OF EPITHELIAL PERMEABILITY BY INTRAEPITHELIAL LYMPHOCYTES INVOLVES NOVEL PROTEIN-SYNTHESIS'. Gastroenterology, 108 (4):331-331. [Details]
KEELY, SJ; SKELLY, MM; ODONOGHUE, DP; BAIRD, AW; (1995) 'BRADYKININ STIMULATES HUMAN COLONIC ION-TRANSPORT IN-VITRO'. Gastroenterology, 108 (4):294-294. [Details]
OMALLEY, KE; FARRELL, CB; OBOYLE, KM; BAIRD, AW; (1995) 'CHOLINERGIC ACTIVATION OF CL- SECRETION IN RAT COLONIC EPITHELIA'. European Journal of Pharmacology, 275 (1):83-89. [Details]
KEELY, SJ; STACK, WA; ODONOGHUE, DP; BAIRD, AW; (1994) 'STIMULATION OF HUMAN COLONIC ION-TRANSPORT IN-VITRO BY ACTIVATION OF PHAGOCYTES'. Gastroenterology, 106 (4):242-242. [Details]
TAYLOR, CT; SKELLY, M; ODONOGHUE, DP; BAIRD, AW; (1994) 'BERBERINE INHIBITION OF EPITHELIAL ION-TRANSPORT'. Gastroenterology, 106 (4):275-275. [Details]
STACK, WA; KEELY, SJ; ODONOGHUE, DP; BAIRD, AW; (1994) 'HISTAMINE STIMULATION OF HUMAN COLONIC ION-TRANSPORT IN-VITRO'. Gastroenterology, 106 (4):572-572. [Details]
OMALLEY, KE; JOYCE, P; BAIRD, AW; (1993) 'NEURONAL CONTRIBUTION TO IMMEDIATE HYPERSENSITIVITY REACTIONS IN ISOLATED COLONIC MUCOSA'. British Journal of Pharmacology, 110 (NA):78-78. [Details]
KEELY, SJ; STACK, WA; ODONOGHUE, DP; BAIRD, AW; (1993) 'HISTAMINE STIMULATION OF HUMAN COLONIC ION-TRANSPORT IS MEDIATED VIA H-1 RECEPTORS'. British Journal of Pharmacology, 110 (NA):79-79. [Details]
Canny, G; Drudy, D; MacMathuna, P; O'Farrelly, C; Baird, AW; (2006) 'Toxigenic C-difficile induced inflammatory marker expression by human intestinal epithelial cells is asymmetrical'. Life Sciences, 78 (9):920-925. [Details]
Quinn, T; Feighery, R; Baird, AW; (2006) 'Role of Rho-kinase in guinea-pig gallbladder smooth muscle contraction'. European Journal of Pharmacology, 534 (1-3):210-217. [Details]
Prieto, P; Baird, AW; Blaauboer, BJ; Ripoll, JVC; Corvi, R; Dekant, W; Dietl, P; Gennari, A; Gribaldo, L; Griffin, JL; Hartung, T; Heindel, JJ; Hoet, P; Jennings, P; Marocchio, L; Noraberg, J; Pazos, P; Westmoreland, C; Wolf, A; Wright, J; Pfaller, W; (2006) 'The assessment of repeated dose toxicity in vitro: A proposed approach - The report and recommendations of ECVAM workshop 56'. Atla-Alternatives to Laboratory Animals, 34 (3):315-341. [Details]
Brayden, DJ; Jepson, MA; Baird, AW; (2005) 'Intestinal Peyer's patch M cells and oral vaccine targeting'. Drug Discovery Today, 10 (17):1145-1157. [Details]
Brayden DJ, Baird AW. (2004) 'Pathogen invasion across intestine: mechanisms and potential exploitation'. Advanced Drugs Delivery Review, 56 (6 No Abstract availa):717-719. [Details]
Quinn T, Molloy M, Smyth A, Baird AW. (2004) 'Capacitative calcium entry in guinea pig gallbladder smooth muscle in vitro'. Life Sciences, 74 (13):1659-1669. [Details]
Baird AW, Campion DP, O'Brien L, Brayden DJ. (2004) 'Oral delivery of pathogens from the intestine to the nervous system'. Journal of Drug Targeting, 12 (2):71-78. [Details]
Hopkins AM, Baird AW, Nusrat A. (2004) 'Targeted docking for exogenous as well as endogenous ligands'. ADVANCED DRUGS DELIVERY REVIEW, 56 (6):763-778. [Details]
Quinn, T; Collins, C; Baird, AW; (2004) 'Mechanisms of neurokinin A- and substance P-induced contractions in rat detrusor smooth muscle in vitro'. Bju International, 94 (4):651-657. [Details]
O'Keeffe, C; Baird, AW; Nolan, N; Mccormick, PA; (2004) 'Cholestatic pruritus - the role of cutaneous mast cells and nerves'. Alimentary Pharmacology & Therapeutics, 19 (12):1293-1300. [Details]
Brayden DJ, Baird AW. (2004) 'Apical membrane receptors on intestinal M cells: potential targets for vaccine delivery'. Advanced Drugs Delivery Review, 56 (6):721-726. [Details]
Goode T, O'Connor T, Hopkins A, Moriarty D, O'Sullivan GC, Collins JK, O'Donoghue D, Baird AW, O'Connell J, Shanahan F. (2003) 'Neurokinin-1 receptor (NK-1R) expression is induced in human colonic epithelial cells by proinflammatory cytokines and mediates proliferation in response to substance P'. Journal of Cellular Physiology, 197 (1):30-41. [Details]
Gaines, S, James, TC, Folan, M, Baird, AW, O'Farrelly, C (2003) 'A novel spectrofluorometric microassay for Streptococcus mutans adherence to hydroxylapatite '. Journal of Microbiological Methods, 54 (3):315-323. [Details]
Cochrane, SW O'Donoghue, DP Brayden, DJ Baird, AW (2003) 'In vitro inhibition of cytochalasin induced tight junction opening in human colon '. Gastroenterology, 124 (4):316-316. [Details]
Forrest, AS Quinn, T Keenan, AK Usher, C Parsons, ME Brayden, DJ Baird, AW (2002) 'Megacolon in the streptozotocin-treated diabetic rat'. British Journal of Pharmacology, 136 . [Details]
Quinn, T Molloy, M Smith, A Baird, AW (2002) 'Capacitative calcium entry in guinea-pig gallbladder smooth muscle '. British Journal of Pharmacology, 136 . [Details]
O'Keeffe, C., Baird, A.W., Nolan, N., and McCormick, P.A. (2002) 'Mast cell hyperplasia in chronic rejection after liver transplantation'. Liver Transplant, 8 :50-57. [Details]
Hopkins, A.M., McDonnell, C., Breslin, N.P., O'Morain, C.A., and Baird, A.W. (2002) 'Omeprazole increases permeability across isolated rat gastric mucosa pre-treated with an acid secretagogue '. Journal of Pharm Pharmacology, 54 :341-347. [Details]
Goh, J., Baird, A.W., O'Keane, C., Watson, R.W., Cottell, D., Bernasconi, G., Petasis, N.A., Godson, C., Brady H.R., and MacMathuna (2001) 'Lipoxin A(4) and aspirin-triggered 15-epi-lipoxin A(4) antagonize TNF-alpha-stimulated neutrophil-enterocyte interactions in vitro and attenuate TNF-alpha-induced chemokine release and colonocyte apoptosis in human intestinal mucosa ex vivo'. Immunology, 167 :2772-2780. [Details]
Cannon, D.M., Keenan, A.K., Guiry, P.J., Buon, C., Baird, A.W., and McBean, G.J. (2001) 'In vitro neuronal and vascular responses to 5-HT in rats chronically exposed to MDMA '. British Journal of Pharmacology, 134 :1455-1460. [Details]
O'Riordan, A.M., Quinn, T., and Baird, A.W. (2001) 'Role of prostaglandin E(2) and Ca(2+) in bradykinin induced contractions of guinea-pig gallbladder in vitro'. European Journal of Pharmacology, 431 :245-252. [Details]
Gullberg, E., Leonard, M., Karlsson, J., Hopkins, A.M., Brayden, D., Baird, A.W., and Artursson, P. (2001) 'Expression of specific markers and particle transport in a new human intestinal M-Cell model'. Biochemical and Biophysical Research Communications, 279 :808-813. [Details]
Moriarty, D., Selve, N., Baird, A.W., and Goldhill, J. (2001) 'Potent NK1 antagonism by SR-140333 reduces rat colonic secretory response to immunocyte activation'. American Journal of Physiology, 280 :852-858. [Details]
Drudy, D., O`Donoghue., Baird, A., Fenelon, L., and O`Farrelly, C. (2001) 'Flow cytometric analysis of Clostridium difficile adherence to human intestinal epithelial cells'. Journal of Medical Microbiology, 50 :526-534. [Details]
Moriarty, D., Goldhill, J., Selve, N., O`Donoghue, D.P., and Baird, A.W. (2001) 'Human colonic anti-secretory activity of the potent NK(1) antagonist, SR140333: assessment of potential anti-diarrhoeal activity in food allergy and inflammatory bowel disease'. British Journal of Pharmacology, 133 :1346-1354. [Details]
McCormack, G., O`Donoghue, D., and Baird, A.W. (2001) 'In-vitro cyclosporin sensitivity of proliferating lymphocytes is predictive of in-vivo therapeutic response in ulcerative colitis'. Ailment Pharmacol Ther, 15 :665-668. [Details]
Skelly, M.M., 0`Donoghue, D.P., and Baird, A.W. (2001) 'Oxygen metabolites in immune-stimulated ion transport in rat colon: modulation by taurine'. Digestion, 6 :124-129. [Details]
Brayden, D.J., and Baird, A.W. (2001) 'Microparticle vaccine approaches to stimulate mucosal immunisation'. Microbes and Infection, 3 (10):867-876. [Details]
O'Riordan, A.M., Quinn, T., Hyland, J.M., O'Donoghue, D.P., Baird, A.W. (2001) 'Sources of calcium in neurokinin A-induced contractions of human colonic smooth muscle in vitro'. American Journal of Gastroenterology, 96 :3117-3121. [Details]
McKay, D.M., and Baird, A.W., (1999) 'Cytokine regulation of epithelial permeability and ion transport'. 44 (2):283-289. [Details]
Stack, W.A., Keely, S.J., 0`Donoghue, D.P., and Baird, A.W. (1995) 'Immune regulation of human colonic electrolyte transport in vitro'. 36 (3):395-400. [Details]
Hide

Show All

Other Journals:

Collins, C.B., Quinn, T., Baird, A.W., Campion, D.P. (2005) 'Histamine-mediated smooth muscle contraction in isolated chicken small intestine occurs via selective Ca2+ channel activation' .

[Details]

L. OBrien, E. Fitzpatrick, A. Baird and D. Campion (2004) 'Neuronal Plasticity in Peyer's patch in response to enteric parasitism' :C55-C55.

[Details]

Conference Publications:

Drudy D., Harnedy, N., Fanning, S., O'Mahony, R., Baird, A. & Kyne L. Antibiotic Resistant Toxin A Negative Toxin B Positive Clostridium difficile In Dublin Ireland The Irish Gerontology Society Scientific meeting Ireland, [Details]

Drudy D., Harnedy, N., Fanning, S., O'Mahony, R., Baird, A. Kyne L. Antibiotic Resistant Toxin A Negative Toxin B Positive Clostridium difficile In Dublin Ireland The Irish Gerontology Society Scientific meeting, September 2005 [Details]

Maher, S., Walsh, E. G., Bahar, B, Baird, A. W. & Brayden, D. J. (2011) Investigations of intestinal epithelial compensatory responses to permeation enhancement caused by sodium caprate (C10) . In: Selected Podium Session, Abstract 179 eds. Transactions of the 38th Int. Soc. Controlled Release Society, Maryland [Details]

Fitzgerald, DC, Meade, KG, McEvoy, AN, Lillis, L, Murphy, EP, MacHugh, DE, Baird, AW, (2007) VET IMMUNOL IMMUNOP Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappa B (NF kappa B) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells , pp.59-68 [Details]

Drudy, D., Narndy, N., Fanning, S., O'Mahony, R., Baird, A. & Kyne, L. (2005) Toxin Variant Clostridium difficile in an Irish teaching hospital The Conway Institute-Festival of Research University College Dublin, , 10-JUN-05 - 11-JUN-05 [Details]

Drudy, D., Narndy, N., Fanning, S., O'Mahony, R., Baird, A. Kyne, L. (2005) High Prevalence of toxin A-negative, toxin B-positive Clostridium difficile in Dublin, Ireland The Irish Society of Gastroenterology Ireland, , 10-JUN-05 - 11-JUN-05 [Details]

Feighery, LM; Quinn, TM; Baird, AW; Brayden, DJ; (2004) MOLECULAR BIOLOGY OF THE CELL Pharmacological manipulation of tight junctions in rat colonic mucosa in vitro , pp.67-67 [Details]
Feighery, LM; Keely, S; Smyth, A; Gilchrist, M; Baird, AW; O'Connor, WT; Brayden, DJ; (2004) MOLECULAR BIOLOGY OF THE CELL Demonstration of compromised ileal structure and function following severe acute trauma to the left forebrain in the isoflourane anaesthetized rat , pp.67-67 [Details]
Soni J, Kearns P., Callanan J.J., Baird A, Bassett H, Brayden D. (2004) Effect of microsphere size on the uptake by rat ileal peyers patch Proceedings of European Society of Veterinary Pathology 22nd Annual Conference Poland, , 01-SEP-04 [Details]
Soni J., Kearns P, Callanan J.J., Baird A.W., Bassett H.F. & Brayden D.J. (2004) In vitro fluorescent microsphere uptake by rat ileal Peyers patches mounted in vertical diffusion chambers: maintenance of functional phenotype Proceedings of Conway Institute of Biomolecular and Biomedical Research, Festival of Research University College Dublin, , 01-SEP-04 [Details]
Cochrane, S; Quinn, T; O'Donoghue, DP; Baird, AW; Brayden, DJ; (2002) BRITISH JOURNAL OF PHARMACOLOGY The effect of myosin light chain kinase inhibition on pharmalogically induced changes in paracellular intestinal epithelial permeability [Details]
Brayden DJ, Feighery LM, Cochrane SW, Quinn T, Baird AW, O'Toole D, Owens SE, O'Donoghue D, Mrsny RJ, (2008) Pharmaceutical research Myosin light chain kinase inhibition: correction of increased intestinal epithelial permeability in vitro , pp.1377-1386 [DOI] [Details]
Collins, CB, McGrath, J, Baird, AW, Campion, DP, (2007) POULTRY SCI Effect of mast cell degranulation on chicken ileal ion transport in vitro , pp.843-849 [Details]
Quinn, T, Feighery, R, Baird, AW, (2006) EUROPEAN JOURNAL OF PHARMACOLOGY Role of Rho-kinase in guinea-pig gallbladder smooth muscle contraction , pp.210-217 [Details]
Brayden, D, Baird, A, (2006) CURRENT OPINION IN PHARMACOLOGY Pharmacology applied: delivering the goods - Editorial overview , pp.491-493 [Details]
Canny, G, Drudy, D, MacMathuna, P, O'Farrelly, C, Baird, AW, (2006) LIFE SCIENCES Toxigenic C-difficile induced inflammatory marker expression by human intestinal epithelial cells is asymmetrical , pp.920-925 [Details]
Brayden DJ, Soni J, Baird AW, O'Brien LM, McElroy M, Callanan JJ, Bassett HF, Campion D, (2006) Journal of controlled release : official journal of the Controlled Release Society Rat, ovine and bovine Peyer's patches mounted in horizontal diffusion chambers display sampling function , pp.68-77 [DOI] [Details]
Brayden, DJ, Jepson, MA, Baird, AW, (2005) DRUG DISCOVERY TODAY Intestinal Peyer's patch M cells and oral vaccine targeting , pp.1145-1157 [Details]
Feighery, LM; Keely, S; Smyth, A; Gilchrist, M; Baird, AW; O'Connor, WT; Brayden, DJ; (2004) Demonstration of compromised ileal structure and function following severe acute trauma to the left forebrain in the isoflourane anaesthetized rat Molecular Biology of the Cell , pp.67-67 [Details]
Cochrane, SW O'Donoghue, DP Jepson, MA Baird, AW (2003) Salmonella typhimurium interactions with an in vitro model of human M-like cells American Gastroenterology Association , pp.480-480 [Details]
Cochrane, SWJ O'Donoghue, DP Baird, AW (2003) Monitoring M cell conversion in vitro: The role of lymphocyte epithelial cell contact British Society of Gastroenterology [Details]
Canny, GO; Mathuna, PM; Brady, H; O'Donoghue, D; Baird, AW; (2000) Vectorial release of interleukin-8 from human colon tissue and Caco-2 cells-attenuation by lipoxin A(4) American Gastroenterology Association , pp.108-108 [Details]
TAYLOR, CT; MURPHY, A; FAN, XG; KELLEHER, D; BAIRD, AW; (1994) EFFECTS OF T-LYMPHOCYTES ON PERMEABILITY OF T84 MONOLAYERS American Gastroenterology Association , pp.782-782 [Details]
OMALLEY, KE; JOYCE, P; BAIRD, AW; (1993) IMMEDIATE HYPERSENSITIVITY REACTIONS IN INTESTINAL MUCOSAE FROM RATS INFECTED WITH FASCIOLA-HEPATICA American Gastroenterology Association , pp.1057-1057 [Details]
TAYLOR, C; BAIRD, AW; (1993) BERBERINE INHIBITS ELECTROGENIC CHLORIDE SECRETION IN RAT COLON IN-VITRO British Pharmacological Society , pp.129-129 [Details]
KEELY, S; STACK, WA; ODONOGHUE, DP; BAIRD, AW; (1993) ACTIVATION OF LAMINA PROPRIA CELLS STIMULATES HUMAN COLONIC TRANSPORT INVITRO American Gastroenterology Association , pp.256-256 [Details]
STACK, WA; KEELY, S; ODONOGHUE, DP; BAIRD, AW; (1993) BASAL AND STIMULATED ELECTRICAL PARAMETERS OF HUMAN COLONIC MUCOSA INVITRO American Gastroenterology Association , pp.281-281 [Details]
WOODS, M; BAIRD, AW; (1993) MODULATION OF BRADYKININ STIMULATION OF ION-TRANSPORT BY GUINEA-PIG GALLBLADDER British Pharmacological Society , pp.153-153 [Details]
KEELY, SJ; OMALLEY, KE; STACK, WA; ODONOGHUE, D; BAIRD, AW; (1992) STIMULATION OF COLONIC ION-TRANSPORT BY ACTIVATION OF CELLS OF THE IMMUNE-SYSTEM British Society of Gastroenterology , pp.68-68 [Details]
WOODS, M; BAIRD, AW; (1992) ENDOGENOUS PEPTIDASES ATTENUATE BRADYKININ-EVOKED ION-TRANSPORT IN GUINEA-PIG GALLBLADDER British Pharmacological Society , pp.151-151 [Details]
Gallagher, T.K., Baird, A.W. and Winter, D.C. (2007) Altered human small bowel contractility in obesity American College of Surgeons [Details]
Drudy, D., Narndy, N., Fanning, S., O'Mahony, R., Baird, A. Kyne, L. (2005) Toxin Variant Clostridium difficile in an Irish teaching hospital The Conway Institute-Festival of Research , 10-JUN-05 - 11-JUN-05 [Details]
Corcoran, D., Quinn, T., Cotter, L., Baird, A. Fanning, S. (2005) Involvement of efflux activity and target gene mutations in fluoroquinolone and erythromycin resistant in Irish human and poultry Campylobacter coli and Campylobacter jejuni isolates The 1st symposium on Antimicrobial Resistance in Animals and the Environment , 23-FEB-05 - 25-FEB-05 [Details]
Hide

Show All

Editorial

Brayden, D,Baird, A (2006) Pharmacology applied: delivering the goods - Editorial overview. Editorial [DOI] [Details]

Brayden, DJ,Baird, AW (2004) Pathogen invasion across intestine: mechanisms and potential exploitation - Preface. Editorial [DOI] [Details]