Professor Michael J. Dunn BSc PhD

Research Interests:

The aim of our research is to identify and implement proteomic technologies and then to apply them to a variety of biomedical research programmes in collaboration with other groups both within the Conway, in other Departments of UCD and other laboratories in Ireland and worldwide. My own research programme is focused in three major areas of biomedicine: (1) cardiovascular proteomics, (2) transplantation proteomics, and (3) neuroproteomics. The overall aim of these studies is to further our understanding of the molecular basis of biological processes in health and disease and to identify new biomarkers that can be exploited as diagnostic/prognostic reagents and/or as therapeutic targets.

FUNDING:
- The Wellcome Trust. Behavioural and sub-cellular dissection of non-rod, non-cone ocular photoreceptors in mice and man (P.I. Professor Russell Foster, Imperial College London, UK) £1,442,656. 2003-2008
- The Wellcome Trust Redox signalling and ischaemic preconditioning: A potential role for protein S-thiolation (P.I. Dr Philip Eaton, King's College London, UK) £175,699. 2003-2006
- British Heart Foundation Role of endothelial cells in graft vasculopathy following cardiac transplantation (P.I. Professor Marlene Rose, Imperial College London, UK) £547,973. 2002-2007
- Science Foundation Ireland (PI David Cotter, RCSI) The investigation of the COMT KO mouse following exposure to cannabis during adolescence: a model for environment interaction and increased vulnerability to schizophrenia
€156,000. (2005-2007)
- Science Foundation Ireland Research Professorship in Biomedical Proteomics: Funding to support 5-year research programme. €3,115,54. (2004-2009)
- Science Foundation Ireland Research Professorship in Biomedical Proteomics, Supplementary Equipment Grant €336,396