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Research

Professor Paul McLoughlin MB, BCh, BAO, BSc, PhD, MRCPI

Book Chapters:

Paul McLoughlin, Michael P. Keane (2011) 'Physiological and Pathological Angiogenesis in the Adult Pulmonary Circulation' In: I. F. McMurtry, W. W. Wagner, T. Stevens, M. N. Gillespie (eds). Comprehensive Physiology. Hoboken, NJ, USA: Wiley Blackwell. Available Online [DOI] [Details]

Peer Reviewed Journals:

Cahill E, Rowan SC, Sands M, Banahan M, Ryan D, Howell K, McLoughlin P (2012) 'The pathophysiological basis of chronic hypoxic pulmonary hypertension in the mouse: vasoconstrictor and structural mechanisms contribute equally'. Experimental Physiology, . [DOI] [Details]
Oliver KM, Lenihan CR, Bruning U, Cheong A, Laffey JG, McLoughlin P, Taylor CT, Cummins EP (2012) 'Hypercapnia induces cleavage and nuclear localization of REL B giving insight into co2 sensing and signalling'. Journal of Biological Chemistry, . [DOI] [Details]
Cahill E, Costello CM, Rowan SC, Harkin S, Howell K, Leonard MO, Southwood M, Cummins EP, Fitzpatrick SF, Taylor CT, Morrell NW, Martin F, McLoughlin P (2012) 'Gremlin plays a key role in the pathogenesis of pulmonary hypertension'. Circulation, 125 (7):920-930. [DOI] [Details]
Costello CM, McCullagh B, Howell K, Sands M, Belperio JA, Keane MP, Gaine S, McLoughlin P. (2011) 'A role for the CXCL12 receptor, CXCR7, in the pathogenesis of human pulmonary vascular disease'. European Respiratory Journal, . [Details]
Sands, M,Howell, K,Costello, CM,McLoughlin, P (2011) 'Placenta growth factor and vascular endothelial growth factor B expression in the hypoxic lung'. Respiratory research, 12 . [DOI] [Details]
Nichol, AD,O'Cronin, DF,Naughton, F,Hopkins, N,Boylan, J,McLoughlin, P (2010) 'Hypercapnic Acidosis Reduces Oxidative Reactions in Endotoxin-induced Lung Injury'. Anesthesiology, 113 :116-125. [DOI] [Details]

Conference Publications:

Keane, PA, O'Brien, C, McLoughlin, P, (2005) INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE The role of the nitric oxide precursor, L-arginine in angiogenesis involving the globally hypoxic adult retina [Details]
Quinn, S, O'Brien, C, McLoughlin, P, (2003) EYE Role of cyclooxygenase and haemoxygenase products in nitric oxide-independent vasodilatation in the porcine ciliary artery , pp.628-636 [DOI] [Details]
Varadarajan, R, Young, L, Quinlan, M, McLoughlin, P, Geoghegan, J, Traynor, O, McEntee, G, Hegarty, JE, O'Farrelly, C, (2002) BRITISH JOURNAL OF SURGERY Nitric oxide expression following reperfusion in human orthotopic liver transplantation , pp.669-669 [Details]
Adamali, HI, Sweeney, M, O'Regan, RG, McLoughlin, P, (2000) JOURNAL OF PHYSIOLOGY-LONDON Role of plasmalemmal Ca2+-ATPase in acidosis-induced relaxation in isolated rat pulmonary and aortic rings , pp.291-292 [Details]
Kilbride, E, McLoughlin, P, Gallagher, C, Harty, H, (2000) JOURNAL OF PHYSIOLOGY-LONDON The incidence of exercise-induced hypoxaemia in a normal healthy female population , pp.49-49 [Details]
Howell, K, Ooi, H, Giles, J, McLoughlin, P, (2000) JOURNAL OF PHYSIOLOGY-LONDON Chronic hypoxia increases alveolar capillary endothelial surface area in adult rats , pp.294-295 [Details]

Editorial

McLoughlin, P,McMurtry, I (2007) Counterpoint: Chronic hypoxia-induced pulmonary hypertension does not lead to loss of pulmonary vasculature. Editorial [Details]