Research
- Research Programmes
- Researchers
- Postdoctoral & Research Fellows
- Featured Researchers
- Conway Fellows
- Conway Clinical Associate Fellows
- Conway Fellows (A-Z)
- Professor Mohamed Al-Rubeai
- Professor Alan Baird
- Dr. John Baugh
- Dr. Orina Belton
- Dr. Oliver Blacque
- Professor Billy Bourke
- Professor David Brayden
- Dr. Lorraine Brennan
- Professor Geraldine Butler
- Dr. Gerard Cagney
- Professor Dolores J. Cahill
- Professor Sean Callanan
- Dr. Marguerite Clyne
- Dr. John Crean
- Dr. Paul Crossey
- Professor Mark Crowe
- Professor Seamas Donnelly
- Professor Michael (Joe) Duffy
- Professor Jim Egan
- Professor Guiliano Elia
- Professor Paul Engel
- Professor Alex Evans
- Dr. Paul Evans
- Dr. Neil Ferguson
- Professor Oliver Fitzgerald
- Professor William Gallagher
- Professor Declan Gilheany
- Professor Catherine Godson
- Professor Stephen Gordon
- Professor Andrew Green
- Professor Patrick Guiry
- Dr. Jana Haase
- Dr. Chandralal Hewage
- Professor Des Higgins
- Professor Suzanne Jarvis
- Professor Michael Keane
- Dr. Breandan Kennedy
- Professor Boris Kholodenko
- Professor Therese Kinsella
- Professor Ulla Knaus
- Professor Walter Kolch
- Professor. Gil Lee
- Professor Brendan Loftus
- Professor Pat Lonergan
- Professor David MacHugh
- Dr. Patricia Maguire
- Professor Kevin Malone
- Professor J.Paul.G Malthouse
- Professor Finian Martin
- Dr. Margaret Mc Gee
- Professor Fionnuala McAuliffe
- Dr. Gethin McBean
- Dr. Amanda McCann
- Dr. Edward McKone
- Professor Paul McLoughlin
- Dr. Hilary McMahon
- Dr. Tara McMorrow
- Professor Walter McNicholas
- Professor Wim Meijer
- Dr. Anika Mostaert
- Professor Grace Mulcahy
- Dr. Keith Murphy
- Dr. Evelyn Murphy
- Dr. Jarlath Nally
- Professor Phillip Newsholme
- Dr. Jens Nielsen
- Dr. Peter O'Brien
- Dr. Kevin O'Connor
- Dr. John O'Connor
- Professor Ronan O'Connell
- Dr. Tadhg O'Croinin
- Dr. James O'Gara
- Professor Donal F. O'Shea
- Professor Stefan Oscarson
- Dr. Francesca Paradisi
- Professor William Powderly
- Professor Prem Puri
- Professor Ciaran Regan
- Professor Helen Roche
- Professor Pauline Rudd
- Professor Dimitri Scholz
- Dr. Noreen Sheehy
- Professor Denis Shields
- Professor Jeremy Simpson
- Dr. Albert Smolenski
- Dr. Matthias Tacke
- Professor Cormac Taylor
- Dr. Emma Teeling
- Professor Douglas Veale
- Professor Dominic Walsh
- Professor William Watson
- Professor Matthias Wilm
- Dr. Xiangming Zhu
- Core Technologies
Professor Prem Puri
Contact Details
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Biography:
Research Interests
| Investigating mechanisms causing some of the common congenital birth defects such as Vesicoureteral reflux, Hirschsprung¿s disease, congenital diaphragmatic hernia and oesophageal atresia |
Book Chapters
| Puri P., Rolle U. ; (2008) 'Development of the Enteric Nervous System' In: Hirschsprung¿s Disease and Allied Disorders, 3rd Edition. Germany: Springer. [Details] |
| Puri P., Montedonico S. ; (2008) 'Pathophysiology of Hirschsprung’s Disease' In: Hirschsprung¿s Disease and Allied Disorders, 3rd Edition. Germany: Springer. [Details] |
| Puri P., Montedonico S.; (2008) 'Hirschsprung’s Disease: Clinical Features' In: Hirschsprung¿s Disease and Allied Disorders, 3rd Edition. Germany: Springer. [Details] |
| Murphy F., Menezes M., Puri P. ; (2008) 'Enterocolitis Complicating Hirschsprung’s Disease' In: Hirschsprung¿s Disease and Allied Disorders, 3rd Edition. Germany: Springer. [Details] |
Peer Reviewed Journals
Thompson, J.,Doi, T.,Power, E.,Balasubramanian, I.,Puri, P.,Bannigan, J.; 'Evidence against a direct role for oxidative stress in cadmium-induced axial malformation in the chick embryo'. Toxicol Appl Pharmacol, 243 (33):390-8390.  [Details] |
| Doi T, Puri P, McCann A, Bannigan J, Thompson J; (2011) 'Epigenetic effect of cadmium on global de novo DNA hypomethylation in the cadmium-induced ventral body wall defect (VBWD) in the chick model'. Toxicological sciences : an official journal of the Society of Toxicology, 120 (2):475-480. [DOI] [Details] |
| Doi, T,Puri, P,Bannigan, J,Thompson, J; (2011) 'Alteration of gene expression of IQGAP1 and Rho-family GTPases in the cadmium-induced ventral body wall defects in the chick model'. Reproductive Toxicology, 32 :124-128. [DOI] [Details] |
| Doi, T,Puri, P,Bannigan, J,Thompson, J; (2011) 'BMPR1A-mediated BMP1 signalling is disrupted in the cadmium-induced omphalocele in the chick model'. Pediatric Surgery International, 27 :617-621. [DOI] [Details] |
| Doi, T,Puri, P,Bannigan, J,Thompson, J; (2011) 'Altered PITX2 and LEF1 gene expression in the cadmium-induced omphalocele in the chick model'. Pediatric Surgery International, 27 :495-499. [DOI] [Details] |
| Ruttenstock, EM,Doi, T,Dingemann, J,Puri, P; (2011) 'Prenatal administration of retinoic acid upregulates connective tissue growth factor in the nitrofen CDH model'. Pediatric Surgery International, 27 :573-577. [DOI] [Details] | |||||||||
| Doi, T,Puri, P,Bannigan, J,Thompson, J; (2011) 'Disruption of GLI3-ZIC3 interaction in the cadmium-induced omphalocele chick model'. Pediatric Surgery International, 27 :205-209. [DOI] [Details] | |||||||||
| Ruttenstock, E,Doi, T,Dingemann, J,Puri, P; (2011) 'Prenatal Administration of Retinoic Acid Upregulates Insulin-Like Growth Factor Receptors in the Nitrofen-Induced Hypoplastic Lung'. Toxicology, 92 :148-151. [DOI] [Details] | |||||||||
| Doi, T,Sugimoto, K,Ruttenstock, E,Dingemann, J,Puri, P; (2011) 'Prenatal treatment with retinoic acid activates parathyroid hormone-related protein signaling in the nitrofen-induced hypoplastic lung'. Pediatric Surgery International, 27 :47-52. [DOI] [Details] | |||||||||
| Dingemann, J,Doi, T,Ruttenstock, E,Puri, P; (2011) 'The role of primary myogenic regulatory factors in the developing diaphragmatic muscle in the nitrofen-induced diaphragmatic hernia'. Pediatric Surgery International, 27 :579-582. [DOI] [Details] | |||||||||
| Dingemann, J,Doi, T,Ruttenstock, E,Puri, P; (2011) 'Expression of the Wilm's tumor gene WT1 during diaphragmatic development in the nitrofen model for congenital diaphragmatic hernia'. Pediatric Surgery International, 27 :159-163. [DOI] [Details] | |||||||||
| Shinkai, T,Shinkai, M,Pirker, MA,Montedonico, S,Puri, P; (2011) 'Spatial and temporal patterns of c-kit positive cells in embryonic lungs'. Pediatric Surgery International, 27 :181-185. [DOI] [Details] | |||||||||
| Doi, T,Shintaku, M,Dingemann, J,Ruttenstock, E,Puri, P; (2011) 'Downregulation of Midkine gene expression and its response to retinoic acid treatment in the nitrofen-induced hypoplastic lung'. Pediatric Surgery International, 27 :199-204. [DOI] [Details] | |||||||||
| Ruttenstock, EM,Doi, T,Dingemann, J,Puri, P; (2011) 'Prenatal retinoic acid treatment upregulates late gestation lung protein 1 in the nitrofen-induced hypoplastic lung in late gestation'. Pediatric Surgery International, 27 :125-129. [DOI] [Details] | |||||||||
| Doi, T,Puri, P,Bannigan, J,Thompson, J; (2011) 'Pre-treatment with N-acetylcysteine upregulates superoxide dismutase 2 and catalase genes in cadmium-induced oxidative stress in the chick omphalocele model'. Pediatric Surgery International, 27 :131-136. [DOI] [Details] | |||||||||
| Ruttenstock, EM,Doi, T,Dingemann, J,Puri, P; (2011) 'IGFBP-4 Gene Overexpression in the Nitrofen-Induced Hypoplastic Lung'. The Journal of pediatrics, 21 :42-45. [DOI] [Details] | |||||||||
| Doi, T,Lukosiute, A,Ruttenstock, E,Dingemann, J,Puri, P; (2011) 'Expression of Iroquois genes is up-regulated during early lung development in the nitrofen-induced pulmonary hypoplasia'. Journal of Pediatric Surgery, 46 :62-66. [DOI] [Details] | |||||||||
| Doi, T,Puri, P,McCann, A,Bannigan, J,Thompson, J; (2011) 'Epigenetic Effect of Cadmium on Global De Novo DNA Hypomethylation in the Cadmium-Induced Ventral Body Wall Defect (VBWD) in the Chick Model'. Toxicological sciences : an official journal of the Society of Toxicology, 120 :475-480. [DOI] [Details] | |||||||||
| Doi T, Puri P, Bannigan J, Thompson J; (2010) 'Disruption of noncanonical Wnt/CA2+ pathway in the cadmium-induced omphalocele in the chick model'. Journal of Pediatric Surgery, 45 (8):1645-1649. [DOI] [Details] | |||||||||
| Doi T, Puri P, Bannigan J, Thompson J.; (2010) 'Disruption of noncanonical Wnt/CA2+ pathway in the cadmium-induced omphalocele in the chick model'. Journal of Pediatric Surgery, 45 (8):1645-1649. [Details] | |||||||||
| Ruttenstock E, Doi T, Dingemann J, Puri P.; (2010) 'Insulinlike growth factor receptor type 1 and type 2 are downregulated in the nitrofen-induced hypoplastic lung'. J Pediatr Surg, 45 (6):1349-1353. [Details] | |||||||||
| Doi T, Puri P, Bannigan J, Thompson J.; (2010) 'HoxB2, HoxB4 and Alx4 genes are downregulated in the cadmium-induced omphalocele in the chick model'. Pediatr Surg Int, . [Details] | |||||||||
| Kutasy B, Hunziker M, Laxamanadass G, Puri P.; (2010) 'Increased incidence of negative appendectomy in childhood obesity'. Pediatr Surg Int, . [Details] | |||||||||
| Ruttenstock E, Doi T, Dingemann J, Puri P.; (2010) 'Insulin receptor is downregulated in the nitrofen-induced hypoplastic lung'. J Pediatr Surg, 45 (5):948-952. [Details] | |||||||||
| Keijzer R, Puri P.; (2010) 'Congenital diaphragmatic hernia'. Semin Pediatr Surg, 19 (3):180-185. [Details] | |||||||||
| Doi, T,Sugimoto, K,Ruttenstock, E,Dingemann, J,Puri, P; (2010) 'Prenatal retinoic acid upregulates pulmonary gene expression of PI3K and AKT in nitrofen-induced pulmonary hypoplasia'. Pediatric Surgery International, 26 :1011-1015. [DOI] [Details] | |||||||||
| Dingemann, J,Doi, T,Ruttenstock, E,Puri, P; (2010) 'Abnormal platelet-derived growth factor signaling accounting for lung hypoplasia in experimental congenital diaphragmatic hernia'. Journal of Pediatric Surgery, 45 :1989-1994. [DOI] [Details] | |||||||||
| Doodnath, R,Puri, P; (2010) 'A systematic review and meta-analysis of Hirschsprung's disease presenting after childhood'. Pediatric Surgery International, 26 :1107-1110. [DOI] [Details] | |||||||||
| Dingemann, J,Puri, P; (2010) 'Isolated hypoganglionosis: systematic review of a rare intestinal innervation defect'. Pediatric Surgery International, 26 :1111-1115. [DOI] [Details] | |||||||||
| Takayasu, H,Murphy, P,Sato, H,Doi, T,Puri, P; (2010) 'Embryonic Wnt gene expression in the nitrofen-induced hypoplastic lung using 3-dimensional imaging'. Journal of Pediatric Surgery, 45 :2129-2135. [DOI] [Details] | |||||||||
| Thompson, J,Doi, T,Power, E,Balasubramanian, I,Puri, P,Bannigan, J; (2010) 'Evidence against a direct role for oxidative stress in cadmium-induced axial malformation in the chick embryo'. Toxicology, 243 :390-398. [DOI] [Details] | |||||||||
| Doi, T,Lukosiute, A,Ruttenstock, E,Dingemann, J,Puri, P; (2010) 'Disturbance of parathyroid hormone-related protein signaling in the nitrofen-induced hypoplastic lung'. Pediatr Surg Int, 26 :45-50. [DOI] [Details] | |||||||||
| Ruttenstock, E,Doi, T,Dingemann, J,Puri, P; (2010) 'Downregulation of insulin-like growth factor binding protein 3 and 5 in nitrofen-induced pulmonary hypoplasia'. Pediatr Surg Int, 26 :59-63. [DOI] [Details] | |||||||||
| Dingemann, J,Doi, T,Ruttenstock, E,Puri, P; (2010) 'Upregulation of Endothelin Receptors A and B in the nitrofen induced hypoplastic lung occurs early in gestation'. Pediatr Surg Int, 26 :65-69. [DOI] [Details] | |||||||||
| Doi, T,Puri, P,Bannigan, J,Thompson, J; (2010) 'Disruption of calreticulin-mediated cellular adhesion signaling in the cadmium-induced omphalocele in the chick model'. Pediatr Surg Int, 26 :91-95. [DOI] [Details] | |||||||||
| Doi, T,Puri, P,Bannigan, J,Thompson, J; (2010) 'Disruption of noncanonical Wnt/CA(2+) pathway in the cadmium-induced omphalocele in the chick model'. Journal of Pediatric Surgery, 45 :1645-1649. [DOI] [Details] | |||||||||
| Doi, T,Puri, P,Bannigan, J,Thompson, J; (2010) 'HoxB2, HoxB4 and Alx4 genes are downregulated in the cadmium-induced omphalocele in the chick model'. Pediatric Surgery International, 26 :1017-1023. [DOI] [Details] | |||||||||
| Hunziker M, Mohanan N, Menezes M, Puri P.; (2010) 'Prevalence of duplex collecting systems in familial vesicoureteral reflux'. Pediatr Surg Int, 26 (1):115-117. [Details] | |||||||||
| Doi T, Ruttenstock E, Dingemann J, Puri P.; (2010) 'Spatiotemporal alteration in phosphatidylinositide 3-kinase-serine/threonine protein kinase B signaling in the nitrofen-induced hypoplastic lung'. J Pediatr Surg, 45 (2):366-371. [Details] | |||||||||
| Hajduk P, Murphy P, Puri P.; (2010) 'Mesenchymal expression of Tbx4 gene is not altered in Adriamycin mouse model'. Pediatr Surg Int, 26 (4):407-411. [Details] | |||||||||
| Kutasy B, Laxamanadass G, Puri P.; (2010) 'Is C-reactive protein a reliable test for suspected appendicitis in extremely obese children?'. Pediatr Surg Int, 26 (1):123-125. [Details] | |||||||||
| Puri P.; (2010) 'The 22nd international symposium on paediatric surgical research'. Pediatr Surg Int, 26 (1). [Details] | |||||||||
| Doi T, Puri P, Bannigan J, Thompson J.; (2010) 'Msx1 and Msx2 gene expression is downregulated in the cadmium-induced omphalocele in the chick model'. J Pediatr Surg, 45 (6):1187-1191. [Details] | |||||||||
| Doi T, Puri P, Bannigan J, Thompson J.; (2010) 'The role of transforming growth factor-beta 2 and 3 in formation of ventral body wall in the cadmium-induced omphalocele chick model'. J Pediatr Surg, 45 (5):989-902. [Details] | |||||||||
| Hunziker M, Mohanan N, D'Asta F, Puri P.; (2010) 'Endoscopic treatment of primary grade V vesicoureteral reflux using hyaluronic acid copolymer (DX/HA)'. Pediatr Surg Int, . [Details] | |||||||||
| Doi T, Sugimoto K, Ruttenstock E, Dingemann J, Puri P.; (2010) 'Prenatal retinoic acid upregulates pulmonary gene expression of PI3K and AKT in nitrofen-induced pulmonary hypoplasia'. Pediatr Surg Int, . [Details] | |||||||||
| Hajduk P, Murphy P, Puri P.; (2010) 'Fgf10 gene expression is delayed in the embryonic lung mesenchyme in the adriamycin mouse model'. Pediatr Surg Int, . [Details] | |||||||||
| O'Donnell AM, Puri P.; (2010) 'The development of excitatory neurons in the chick cloaca'. Pediatr Surg Int, 26 (1):111-114. [Details] | |||||||||
| Thompson J, Doi T, Power E, Balasubramanian I, Puri P, Bannigan J; (2010) 'Evidence against a direct role for oxidative stress in cadmium-induced axial malformation in the chick embryo'. Toxicology and applied pharmacology, 243 (3):390-398. [DOI] [Details] | |||||||||
| Ruttenstock E, Puri P.; (2009) 'A meta-analysis of clinical outcome in patients with total intestinal aganglionosis'. Pediatr Surg Int, 25 (10):833-839. [Details] | |||||||||
| O'Donnell, A. M.,Puri, P.; (2009) 'Cholinergic innervation in the developing chick cloaca and colorectum'. J Pediatr Surg, 44 (2):392-4. [Details] |
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| Oberritter, Z,Rolle, U,Juhasz, Z,Cserni, T,Puri, P; (2009) 'Altered expression of c-kit-positive cells in the ureterovesical junction after surgically created vesicoureteral reflux'. Pediatr Surg Int, 25 :1103-1107. [DOI] [Details] | |||||||||
| Cserni, T.,O' Donnel A,Paran, S.,Puri, P.; (2009) 'Correlation of enteric NADPH-d positive cell counts with the duration of incubation period in NADPH-d histochemistry'. Pathol Oncol Res, 15 (1):103-7. [Details] |
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Internal Collaborators
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