Professor Sabine Koelle

Research

Professor Sabine Koelle PhD and Habilitation

Contact Details

Title	Full Professor of Anatomy & Developmental Biology
Address	School Of Medicine Health Sciences Centre Belfield Dublin 4
Telephone:	Ext. 6636
Email:	ei.dcu@elleok.enibas

Biography:

Sabine Koelle is Professor of Anatomy and Developmental Biology at the University College Dublin, School of Medicine and Medical Sciences. She graduated in Veterinary Medicine at the University of Munich, where she also took part in the studies of medicine and dentistry. She worked as assistant professor in the Max-Planck Instiute of Biochemistry and Psychiatrics in Martinsried in Germany and received her habilitation in the Institute of Veterinary Anatomy, Histology and Embryology of the Veterinary School of the University of Munich. In 2004 she was appointed as associate professor in the Institute of Anatomy, Histology and Embryology in the Veterinary School of the University of Giessen, Germany. In 2009 she was appointed as Head of the Department of Anatomy, Histology and Embryology at the University of Vienna, Austria.

Sabine Koelle has received two scholarships enabling her to work at Cornell University and Texas A&M University, USA. She has worked as visiting professor in France, Argentina, Spain, Hungary and Italy. She is winner of numerous research awards and is known for excellent scientific photography and video imaging.

Research Interests

Professor Koelle`s research is focused on reproductive medicine, especially on improving the results of assisted reproduction. Recent research projects include the mechanisms of gameto-maternal interaction, embryo-maternal communication and early embryogenesis in humans and animals. Additionally she is establishing new criteria for functional sperm and oocyte assessment and is developing new methods for in vivo imaging of fertilization and early embryogenesis in the female genital tract.

Grants

Duration	Funder	Project title
2017-2021	Teagasc	Walsh Fellowship Award: Development and validation of predictive tests for bull fertility
2016-2021	WT 203930/7/16/7	Wellcome Trust Clinician PhD Programme Project: Endometriosis and its effects on tubal function
2016-2020	DAFM 15S732	New strategies to predict and monitor semen fertility
2015-2017	IRC	How do elevated estrogen levels affect male fertility?
2015-2017	GNA	Effect of inflammation on gameto-maternal interaction in the oviduct
2015-2017	UCD SEED	Prolonging survival time of spermatozoa in the female genital tract
2014-2015	FBF	New aspects of preserving and promoting motility in bovine sperm
2012-2014	Swiss Genetics	Increase of sperm vitality and motility by addition of cell extracts and andmatrix components
2012-2013	FBF	New methods for maintaining membrane integrity in bovine sperm
2010-2012	AAOS	Gameto-maternal interaction: new aspects using a new digitalvideomicroscopic system
2008-2011	EU Cost FA0702	Maternal interaction with gametes and embryos
2007-2011	DFG KO139875-1	Mechanisms of oocyte and embryo transport in the oviduct: Regulation by the epithelial cholinergic system
2010-2011	IntervetGmbH	Effects of GnRH and PGF2alpha and their analogues on early embryo-maternal communication
2008-2012	FBF	Survival of sperm in the female genital tract - phyiology and influence of sperm diluents
2007	DFG GK 455	Interaction of the oocyte and the embryo with the maternal genital tract.
2005-2007	DFG GK 455	Molecular characterization of the interaction of cumulus cells and oocyte before and after maturation
2002-2005	DFG FOR 478	Mechanisms of embryo-maternal communication (Research Group)

IRC: Irish Research Council, GNA: Government of Nigeria, Africa, FBF: Association for the Promotion of Research in Bioeconomics, AAOS: Austrian Academy of Sciences, DFG: German Research Foundation.

UCD Medicine Research Centre: Human Reproduction

Research Projects

Sponsor : Dept. Agriculture, Food and the Marine (DAFM)
Title : New strategies to predict and monitor semen fertility (FERTILEBULL)
Start Date / End Date : 01-DEC-16 / 30-NOV-20

Sponsor : University College Dublin (UCD)
Title : OBRSS Research Support Scheme
Start Date / End Date : 01-NOV-16 / 31-OCT-19

Sponsor : University College Dublin (UCD)
Title : Novel concepts for the early diagnosis of cervical cancer
Start Date / End Date : 01-APR-17 / 30-SEP-18

Sponsor : University College Dublin (UCD)
Title : Transfer Account from Forderverein Biotechnologieforschung (FBF), Bonn Germany
Start Date / End Date : 01-JUL-13 / 30-JUN-15

Sponsor : University College Dublin (UCD)
Title : Transfer Account from IMV Technologies, France
Start Date / End Date : 01-JUL-13 / 30-JUN-15

Sponsor : University College Dublin (UCD) Title : Transfer Account from Swiss Genetics, Switzerland Start Date / End Date : 01-JUL-13 / 30-JUN-15
Sponsor : IMV Technologies Title : Transfer Account from IMV Technologies, France Start Date / End Date : 01-JUL-13 / 30-APR-14
Sponsor : Fördeverein Biotechnologieforschung e.V. (FBF) Title : Transfer Account from Forderverein Biotecnhologieforschung (FBF), Bonn, Germany Start Date / End Date : 01-JUL-13 / 30-JUN-15
Sponsor : Swissgenetics Title : Transfer Account from Swiss Genetics, Switzerland Start Date / End Date : 01-JUL-13 / 30-JUN-15
Sponsor : Fördeverein Biotechnologieforschung e.V. (FBF) Title : New aspects of preserving and promoting motility in bovine sperm Start Date / End Date : 01-JUL-14 / 31-DEC-17
Sponsor : University College Dublin (UCD) Title : Reproduction Start Date / End Date : 01-JUN-13 / 31-DEC-18
Sponsor : University College Dublin (UCD) Title : Prolonging Survival Time of Spermatozoa in the Bovine Female Genital Tract Start Date / End Date : 01-APR-15 / 31-MAR-17
Sponsor : Irish Research Council (IRC) Title : How do elevated estrogen levels affect male fertility? Start Date / End Date : 01-OCT-15 / 30-SEP-17
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Recent Postgraduates

Recent :

Susanne Bour

Katharina Noreikat

Beatrice Borkenhagen

Regina Leeb

Current:

Myles Leavy

Kate Dulohery

Barbara Hughes

Deirdre Scully

Miguel Camara Pirez

Heather Steele

Current Postgraduate Students

Heather Steele, Doctor of Philosophy (PhD) - Thesis Supervisor

itagar Eseoghene, Doctor of Philosophy (PhD) - Thesis Supervisor

Barbara Hughes, Doctor of Philosophy (PhD) - Thesis Supervisor

Miguel Camara Pirez, Doctor of Philosophy (PhD) - Thesis Supervisor

Myles Leavy, Doctor of Philosophy (PhD) - Thesis Supervisor

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Books

Kölle S, Trottmann M (2016) In vivo microscopy in the male and female reproductive tract. Bellingham, WA, USA: SPIE. [DOI] [Details]

Book Chapters

Budras KD, Kölle S (2014) 'Anatomy of the Pelvis, the Inguinal Region and the Urogenital Tract' In: Mülling C, Pfarrer C, Reese S, Kölle S, Budras KD (eds). Atlas of the Anatomy of the Horse (German). Hannover: Schlüterscher Verlag. [Details]

Kölle S, Reese S, Mülling C (2014) 'Anatomy of the Head' In: Mülling C, Pfarrer C, Reese S, Kölle S, Budras KD (eds). Atlas of the Anatomy of the Horse (German). Hannover: Schlüterscher Verlag. [Details]

Kölle S (2012) 'Live Cell Imaging of the Oviduct' In: Kölle S (eds). Methods of Enzymology. Burlington: Elsevier, Academic Press. [DOI] [Details]

Koelle, S; Wehrend, A (2012) 'Pregnancy and Birth' In: Koelle, S; Wehrend, A (eds). Canine Neonatology (German). Hanover: Schluterscher Verlag. [Details]

Kölle S (2012) 'Anatomy of the Urogenital Tract and the Pelvis' In: Kölle S (eds). Atlas of the Anatomy of the Dog (German). Hannover: Schlüterscher Verlag. [Details]

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Edited Books

Mülling C, Pfarrer C, Reese S, Kölle S, Budras KD (Ed.). (2014) Atlas of the Anatomy of the Horse (German). Hannover, Germany: Schlüterscher Verlag. [Details]

Reese S, Muelling C, Pfarrer C, Kölle S, Budras KD (Ed.). (2012) Atlas of the Anatomy of the Dog (German). Hannover: Schlueterscher Verlag. [Details]

Peer Reviewed Journals

Fernandez-Fuertes, B; Laguna-Barraza, R; Fernandez-Gonzalez, R; Gutierrez-Adan, A; Blanco-Fernandez, A, O`Doherty, A; Di Fenza, M; Kelly AK; Kölle S, Lonergan, P (2017) 'Subfertility in bulls carrying a nonsense mutation in transmembrane protein 95 is due to failure to interact with the oocyte vestments'. Biology of Reproduction, 97 (1):50-60. [DOI] [Details]

Leavy, M; Trottmann M; Liedl, B; Reese, S; Stief, C; Freitag, B; Baugh, J; Spagnoli, G; Koelle S (2017) 'Effects of elevated beta-estradiol levels on the functional morphology of the testis - new insights'. Scientific Reports, 7 (39931):1-11. [DOI] [Details]

Trottmann, M; Sroka, R; Stepp, H; Liedl, B; Becker, AJ; Stief, CG; Kölle, S (2016) 'Probe-based confocal laser endomicroscopy (pCLE): a preclinical investigation of the male genital tract'. Lasers in Medical Science, 31 (1):57-65. [DOI] [Details]

O'Doherty, AM; Di Fenza, M; Kolle, S (2016) 'Lipopolysaccharide (LPS) disrupts particle transport, cilia function and sperm motility in an ex vivo oviduct model'. Scientific Reports, 6 (24583). [DOI] [Details]

Trottmann, M; Sroka, R; Stepp, H; Liedl, B; Becker, AJ; Stief, CG; Kölle, S. (2015) 'Probe-based confocal laser endomicroscopy (pCLE): A preclinical investigation of the male genital tract'. Lasers in Medical Science, . [Details]

Kölle S (2015) 'Transport, distribution and elimination of mammalian sperm following natural mating and insemination'. Reproduction in Domestic Animals, (Suppl 3):2-6. [DOI] [Details]
Kölle S (2015) 'Bovine sperm-oviduct interaction ¿new insights by the use of novel imaging techniques'. Tierarztliche Umschau, 70 :351-355. [Details]
Trottmann, M; Kölle, S; Leeb, R; Doering, D; Reese, S; Stief, CG; Dulohery, K; Leavy, M; Kuznetsova, J; Homann, C; Sroka, R. (2015) 'Ex vivo investigations on the potential of optical coherence tomography (OCT) as a diagnostic tool for reproductive medicine in a bovine model'. Journal of Biophotonics, . [DOI] [Details]
Trottmann. M; Sroka. R; Stepp. H; Heide. M; Liedl. B; Reese. S; Becker. A; Stief. CG; Kölle. S. (2015) 'Probe-based confocal laser endomicroscopy (pCLE) - a new imaging technique for in situ localization of spermatozoa'. Journal of Biophotonics, 8 :415-421. [DOI] [Details]
Pausch H, Kölle S, Wurmser C, Schwarzenbacher H, Ermmerling R, Jansen S, Trottmann M, Fürst C, Götz KU,Fries R (2014) 'A nonsense mutation in TMEM 95 encoding a nondescript transmembrane protein causes idiopathic male infertility in cattle'. PLoS Genetics, . [DOI] [Details]
Trottmann M, Sroka R, Stepp H, Heide M, Liedl B, Reese S, Becker A, Stief CG, Kölle S (2014) 'Probe-based confocal laser endomicroscopy (pCLE) - a new imaging technique for in situ localization of spermatozoa'. Journal Of Biophotonics, . [Details]
Wolff M, Noreikat K, Ibanez-Tallon I, Lips KS, Kölle S, Kummer W (2012) 'Cholinergic receptors in the murine oviduct: Inventory and coupling to intracellular calcium concentration'. Life Sciences, . [DOI] [Details]
Noreikat K, Wolff M, Kummer W, Kölle S (2012) 'Ciliary activity in the oviduct of cycling, pregnant and muscarinic knockout mice'. Biology of Reproduction, . [DOI] [Details]
Kölle S, Reese S, Kummer W (2010) 'New aspects of gamete transport, fertilization and embryonic development in the oviduct gained by live cell imaging'. Theriogenology, 73 :786-795. [DOI] [Details]
Kölle S, Dubielzig S, Reese S, Wehrend A, Koenig P, Kummer W (2009) 'Ciliary transport, gamete interaction and effects of the early embryo in the oviduct: ex vivo analyses using a new digital videomicroscopic system in the cow'. Biology of Reproduction, 81 :276-274. [DOI] [Details]
von Witzendorff D, Maass K, Pitch A, Ebeling S, Kölle S, Kocel C, Eklasi-Hundriser M, Geyer H, Geyer R, Töpfer-Peterson E (2009) 'Characterization of the acidic N-linked glycans of the zona pellucida of prepuberal pigs by a mass spectrometric approach'. Carbohydrate Research, 344 :1541-1549. [DOI] [Details]
Kölle S, Dubois CS, Caillaud M, Lahuec C, Sinowatz F, Goudet G (2007) 'Equine zona protein synthesis and ZP structure during folliculogenesis, oocyte maturation and embryogenesis'. Molecular Reproduction and Development, 74 :851-859. [Details]
Rottmayer R, Ulbrich SE, Kölle S, Prelle K, Neumueller C, Sinowatz F, Meyer HDH, Wolf E, Hiendleder S (2006) 'A bovine oviduct epithelial cell suspension culture system suitable for studying embryo-maternal interactions: Morphologcical and functional characterization'. Reproduction, 132 :637-648. [Details]
Kaiser GG, Kölle S, Boie G, Sinowatzz F, Palma G, Alberio RH (2006) 'In vivo effect of growth hormone on the expression of connexin 43 in bovine ovarian follicles'. Molecular Reproduction and Development, 73 :600-606. [Details]
Conrad M, Moreno SG, Sinowatz F, Ursini F, Kölle S, Roveri A, Birelmeier M, Wurst W, Maiorino M, Bornkamm GW (2005) 'The nuclear form of phospholipid hydroperoxid glutathione peroxidase is a protein thiol peroxidase contributing to sperm chromatin stability'. Molecular and Cellular Biology, 25 :7637-7644. [Details]
Kölle S, Stojkovic M, Rese S, Reichenbach HD, Wolf E, Sinowatz F (2004) 'Effect of growth hormone on the ultrastructure of bovine preimplantation embryos'. Cells Tissues Organs, 317 :101-108. [Details]
Haenisch-Woehl A, Kölle S, Neumüller C, Sinowatz F, Braun J (2003) 'Morphology of canine cumulus-oocyte-complexes in prebpuberal bitches'. Anatomia, histologia, embryologia, 32 :1-5. [Details]
Wolf E, Arnold GJ, Bauersachs S, Beier HM, Blum H, Einspanier R, Fröhlich T, Herrler A, Hiendleder S, Kölle S, Prelle K, Reichenbach HD, Rief S, Stojkovic M, Wenigerkind H, Sinowatz F (2003) 'Embryo-maternal communication in bovine - strategies for deciphering a complex crosstalk'. Reproduction in domestic animals = Zuchthygiene, 38 :276-289. [Details]
Kölle S, Sinowatz F (2003) 'Influence of growth hormone and growth factors on embryonic development'. The Journal of reproductive medicine, 19 :40-47. [Details]
Kölle S, Stojkovic M, Boie G, Wolf E, Sinowatz F (2003) 'Growth hormone-related effects on apoptosis, mitosis and expression of connexin 43 in bovine IVM cumulus-oocyte-complexes'. Biology of Reproduction, 68 :1584-1589. [Details]
Stojkovic M, Kreis O, Kölle S, Prelle K, Assmann V, Zahkharchenko V, Sinowatz F, Wolf E (2003) 'Developmental regulation of hyaluronan-binding protein (RHAMM/IHABP) expression in early bovine embryos'. Biology of Reproduction, 68 :60-66. [Details]
Stojkovic M, Kölle S, Peinl S, Stojkovic P, Zakharchenko V, Thompson JG, Wenigerkind H, Reichenbach HD, Sinowatz F, Wolf E (2002) 'Effect of high concentrations of hyluronan in culture medium on development and survival rates of fresh and frozen-thawed bovine embryos produced in vitro'. Reproduction, 124 :141-153. [Details]
Kölle S, Stojkovic M, Boie G, Wolf E, Sinowatz F (2002) 'Growth hormone inhibits apoptosis in in vitro produced embryos'. Molecular Reproduction and Development, 61 :180-186. [Details]
Sinowatz F, Töpfer-Petersen E, Kölle S, Palma G (2001) 'Functional morphology of the zona pellucida'. Anatomia, histologia, embryologia, 30 :257-263. [Details]
Kölle S, STojkovic M, Prelle K, Waters M, Wolf E, Sinowatz F (2001) 'Growth hormone/Growth hormone receptor expression and GH-mediated effects during early bovine embryogenesis'. Biology of Reproduction, 64 :1826-1834. [Details]
Sinowatz F, Kölle S, Töpfer-Perterson E (2001) 'Biosynthesis and expression of zona pellucida glycoproteins in mammals'. Cells Tissues Organs, 168 :24-35. [Details]
Sinowatz F, Schams D, Kölle S, Plath A, Lincoln D, Wates MJ (2000) 'Cellular localization of GH receptor in the bovine mammary gland during mammogenesis, lactation and involution'. Endocrinology, 166 :503-510. [Details]
Sinowatz F, Scahms D, Plath A, Kölle S (2000) 'Expression and localization of growth factors during mammary gland development'. Advances in experimental medicine and biology, 480 :19-25. [Details]
Temmim L, Kölle S, Temmim-Baker H, Sinowatz F (2000) 'Expression of growth hormone receptor in human liposarcomas and lipomas'. Oncology Reports, 7 :757-760. [Details]
Lincoln D, Sinowatz F, Kölle S (1999) 'Up-regulation of growth hormone receptor immunoreactivity in human melanoma'. Anticancer Research, 19 :1919-1931. [Details]
Kölle S, Stojkovic M, Hutzler P, Wolf E, Sinowatz F (1999) 'Influence of growth hormone and insulin-like growth factor-I on apoptosis in bovine cumulus-oocyte-complexes matured in vitro'. Theriogenology, 51 . [Details]
Stojkovic M, Motlik J, Kölle S, Zakhartchenko V, Alberio R, Sinowatz F, Wolf E (1999) 'Cell-cycle control and oocyte maturation: Review of literature'. Reproduction in Domestic Animals, 34 :335-342. [Details]
Kölle S, Sinowatz F, Boie G, Temmim-Baker L, Lincoln D (1999) 'Expression of gorwth hormone receptor in human prostatic carcinoma and hyperplasia'. International Journal of Oncology, 14 :911-916. [Details]
Sinowatz F, Plendl J, Kölle S (1998) 'Protein-carbohydrate interactions during fertilization'. Acta Anatomica, 161 :196-205. [Details]
Kölle S, Sinowatz F, Boie G, Lincoln D (1998) 'Developmental changes in the expression of the growth hormone receptor messenger ribonucleic acid and protein in the bovine ovary'. Biology of Reproduction, 59 :836-842. [Details]
Knabel M, Kölle S, Sinowatz F (1998) 'Experssion of growth hormone receptor in the bovine mammary gland during prenatal development'. Anatomy and Embryology, 198 :163-169. [Details]
Suarez SS, Revah I, Lo M, Kölle S (1998) 'Bull sperm binding to oviductal epithelium is mediated by a Ca2+dependent lectin on sperm which recognizes Lewis A trisaccharide'. Biology of Reproduction, 59 :39-44. [Details]
Kölle S, Sinowatz F, Boie G, Palma GA, STojkovic M, Wolf E (1998) 'Topography of gowth hormone receptor expession in the bovine embryo'. Histochemistry and Cell Biology, 109 :417-419. [Details]
Totzauer I, Kölle S, Sinowatz F, Plendl J, Amselgruber W, Töpfer-Petersen E (1998) 'Localization of the zona glycoproteins ZPB and ZPC in the bovine ovary during pre-and postantal development'. Journal of Anatomy, 180 :37-43. [Details]
Kölle S, Sinowatz F, Boie G, Palma G (1998) 'Differential expression of ZPC in the bovine ovary, oocye and embryo'. Molecular Reproduction and Development, 49 :435-443. [Details]
Lincoln DT, Sinowatz F, Temmim-Baker L, Baker HI, Kölle S, Waters MJ (1998) 'Growth hormone receptor expression in the nucleus and cytoplasm of normal and neoplastic cells'. Histochemistry and Cell Biology, 109 :141-159. [Details]
Jagla W, Wiede A, Kölle S, Hoffmann W (1998) 'Differential expression of the TFF peptides xP1 and xP4 in the gastrointestinal tract of Xenopus laevis'. Cells Tissues Organs, 291 :13-18. [Details]
Kölle S, Sinowatz F, Boie G, Lincoln D, Waters MJ (1997) 'Differential expression of the growth hormone receptor and its transcript in bovine uterus and placenta'. Molecular and Cellular Endocrinology, 131 :127-136. [Details]
Lincoln DT, Sinowatz F, Kölle S, Baker H, Temmim-Baker L (1997) 'Increased growth hormone receptor immunoreactivity in human melanoma tumours'. Histochemistry and Cell Biology, 108 . [Details]
Kölle S, Sinowatz F, Boie G, Totzauer I, Amselgruber W, Plendl J (1996) 'Localization of the mRNA encoding the zona protein ZP3beta in the procine ovary, oocyte and embryo by non-radioactive in situ hybridization'. Histochemical Journal, 28 :441-447. [Details]
Sinowatz F, Amselgruber W, Lincoln D, Sasse J, Kölle S, Plendl J, Kayser K (1995) 'Role of basic fibroblast growth factor in prostatic tumors'. Nutrition, 11 :619-621. [Details]
Sinowatz F, Amselgruber W, Plendl J, Kölle S, Neumüller C, Boos G (1995) 'Effects of hormones on the prostate in adult and aging men and animals'. Microscopy Research and Technique, 30 :282-292. [Details]
Amselgruber W, Sinowatz F, Kölle S, Lincoln D, Kayser K (1995) 'Expression of Galactosyltransferase in prostatic tumors'. Nutrition, 11 :638-642. [Details]
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Other Journals

Kölle S (2015) 'Gamete transport, fertilization and early embryogenesis: new insights by live cell imaging (German)' Gyne 2 (1) :20-25. [Details]

Conference Publications

Owhor, I; Koelle, S (2016) Bovine salpingitis: a hidden cause of infertility 13th Annual Conference of the Anatomical Society of Nigeria [Details]

Owhor, I; Koelle, S (2017) Bovine salpingitis - effects on oviductal microarchitecture and fertility Annual Conference of Physiology and Pathology of Reproduction [Details]

Fernandez-Fuertes, B; Kölle, S; Lonergan, P (2017) Subfertility in bulls carrying a nonsense mutation in TMTM 95 is due to failure to penetrate the zona pellucida 43rd Annual Conference of the International Embryo Technology Society [Details]

Scully, D; Kölle, S (2017) Bovine cystic ovary disesase: how does it affect tubal functional integrity and gameto-maternal interaction? Annual Conference of Physiology and Pathology of Reproduction [Details]

Hughes, B; Kölle, S (2017) Tubal sperm storage in humans versus animals - the rservoir redefined Annual Conference of Physiology and Pathology of Reproduction [Details]

Kölle, S (2017) Gameto-maternal interaction and early embryo-maternal communication - new insights by cutting edge technologies Nordic Fertility Society Meeting [Details]
Kölle, S; Leeb, R; Trottmann, M (2017) Prolonging survival time of spermatozoa in the female genital tract Annual Conference of Physiology and Pathology of Reproduction [Details]
Owhor, L; Reese, S; Kölle S (2017) Clinical anatomy of bovine salpingitis - a new approach using live cell imaging Anatomists on the Edge Conference [Details]
Scully, D; Reese, S; Kölle S (2017) Cystic ovary disease and its effects on the bovine oviduct: novel concepts Anatomists on the Edge Conference [Details]
Kölle, S (2017) In vivo imaging of the male and female genital tract Anatomists on the Edge Conference [Details]
Dulohery, K; Kölle, S (2016) What are the effects of salbutamol on gameto-maternal interaction?: New Insights by Cutting Edge Imaging Technologies 44th Annual Meeting, European Teratology Society (ETS) Dublin, [DOI] [Details]
Koelle, S; Scully, D; Eseoghene, L (2016) Effects of salpingitis on bovine reproductive success: novel concepts using live cell imaging World Buiatrics Conference Dublin, [Details]
Hughes, B; Kölle, S (2016) The effect of selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines on the functional integrity of the human fallopian tube 44th Annual Meeting, European Teratology Society (ETS) Dublin, [DOI] [Details]
Hughes, B; Kölle, S (2016) Formation of the Human Sperm Reservoir Rotunda Hospital Research Day Rotunda Hospital, Dublin, , 02-JUN-16 - 02-JUN-16 [Details]
Hughes, B; Koelle, S (2016) Human Sperm Oviduct Interaction ¿ The secret life of sperm Irish Fertility Society (IFS) 10th Annual Scientific Meeting and AGM Clane, [Details]
Hughes, B; Kölle, S (2016) Inside the human fallopian tube - A new journey in Live Cell Imaging Microscopy Society of Ireland (MSI) Symposium Dublin, [Details]
Hughes, B; Koelle, S (2016) The human sperm reservoir: fact or fiction? Royal Academy of Medicine in Ireland (RAMI) Biomedical Sciences Meeting Cork, [Details]
Scully, D; Di Fenza, M; Hughes, B; Kölle, S (2016) How do ovarian cysts affect the function of the bovine oviduct? New insights by live cell imaging and histochemical analyses Microscopy Society of Ireland (MSI) Symposium Ireland DIT, Dublin, [Details]
Koelle, S. (2015) Prolonging survival time in the female genital tract - new insights EU AI Vets Conference Albena, Bulgaria, , 16-SEP-15 - 17-SEP-15 [Details]
Koelle, S. (2015) Gameto-maternal interaction and early embryo-maternal communication - novel insights on metabolic effects using live cell imaging Ovarian Club Conference Barcelona, , 14-NOV-15 - 15-NOV-15 [Details]
Hughes, B; Kölle, S (2015) Sperm-oviduct interaction in the human - new insights using live cell imaging European Society of Human Reproduction Conference Lisboa, Portugal, , 14-JUN-15 - 17-NOV-15 [Details]
Trottmann, M; Kölle, S; Homann, C; Stepp, H; Döring, D; Leeb, R; Reese, S; Stief CG; Sroka, R. (2015) Potential of optical coherence tomography (OCT) and probe-based confocal laserendomicroscopy (pCLE) in the investigation of the testis - a feasibility study American Urological Association Annual Meeting , 18-MAY-15 - 18-NOV-15 [Details]
Kölle, S; Liedl, B; Alba-Alejandre, I; Stief, CG; Trottmann, M. (2015) PCLE - a valuable tool for assessment of the female genital tract ICCU-Conference Lisboa, Portugal, , 10-APR-15 - 12-APR-15 [Details]
Trottmann, M; Kölle, S; Homann, C; Döring, D; Leeb, R; Reese, S; Stief, CG; Sroka, R. (2015) Minimally invasive imaging in andrology - Potential of OCT and pCLE 30th Annual European Association of Urology , 21-MAR-15 [Details]
Kölle, S; Alba-Alejandre, I; Leeb, R; Sroka, R; Stepp, H; Liedl, B; Dulohery, K; Stief, CG; Trottmann M. (2015) Probed-based confocal laser endomicroscopy (pCLE): a new life cell imaging technique to evaluate sperm-oviduct interaction BIOS SPIE Photonics West San Francisco; US, , 07-FEB-15 [Details]
Trottmann, M; Homann, C; Leeb, R; Döring, D; Kuznetsova, J; Reese, S; Stief, CG; Kölle, S; Sroka, R. (2015) Investigation of the potential of optical coherence tomography (OCT) as a non-invasive diagnostic tool in reproductive medicine BIOS SPIE Photonics West San Francisco; USA, , 07-FEB-15 [Details]
Koelle, S (2015) Transport, distribution and elimination of sperm following natural mating and insemination ESDAR (European Society for Domestic Animal Reproduction) Conference Albena, Bulgaria, , 16-SEP-15 - 17-SEP-15 [Details]
Koelle, S (2015) Human sperm oviduct interaction ¿ Clinical applications ÄRE (Ärztinnen in der Reproduktionsmedizin) Workshop Freiburg, Germany, , 24-OCT-15 - 24-OCT-15 [Details]
Koelle, S (2015) New imaging techniques in the female genital tract ¿ tools for improving the diagnosis Annual Meeting of Gynecologists Frankfurt, Germany, , 24-APR-15 - 25-APR-15 [Details]
Trottmann M, STepp H, Stoka R, Heide M, Liedl B, Reese S, Becker Aj, Stief CG,Kölle S (2014) Probe-based confocal laser endomicroscopy (pCLE) - a new imaging technique for in situ localization of spermatozoa International Converence on Laser Applications in Life Sciences (LALS) [Details]
Trottmann M, Liedl B, Stepp H, Leeb R, Heide M, Becker AJ, Stief CG, Kölle S (2014) Differentiatin of testicular tissue and in situ localization of vital spermatozoa by probe-based confocal laser endomicroscopy (pCLE) BIOS SPIE Photonics West [Details]
Kölle S, Liedl B, Alba-Alejandre I, STeif CG, Trottmann M (2014) PCLE as a new diagnostic tool in the female genital tract ICCU International Conference [Details]
Freitag B, Sroka R, Kölle S,Becker AJ, Khoder W, Pongratz T, Stief CG, Trottmann M (2014) Intraluminal occlusion of the seminal duct by laser and histoacryl: two non-invasive alternatives for vasectomy BIOS SPIE Photonics West [Details]
Leeb R, Trottmann M, Reese S, Stief CG, Kölle S (2014) How does the pH affect motility, vitality and mitochondrial activity of spermatozoa? 40th Conference of the Bavarian and Austrian Society of Urology and Andrology [Details]
Zellner S, Trottmann M, Reese S, Leeb R, Becker Aj, Stief CG, Kölle S (2014) Evaluation of vitality in the seprmiogram - limiting aspects and possible alternatives 40th Conference of the Bavarian and Austrian Society of Urology and Andrology [Details]
Leavy M, Kölle S, Liedl B, Stief CG, Trottmann M (2014) How does estrogen affect the functional integrity of the testis? 40th Conference of the Bavarian and Austrian Society of Urology and Andrology [Details]
Kölle S, Leeb R, Trottmann M (2014) Live cell imaging in the female genital tract - new aspects for improving cow fertility International Cow Fertility Conference - New Science, New Practices [Details]
Dulohery K, Trottmann M, Liedl B, Reese S, Steif CG, Kölle S (2014) How do elevated levels of testosterone affect fertility and integrity of the female genital tract? RAMI Biomedical Sciences Annual Meeting [Details]
Leavy M, Trottmann M, Liedl b, Reese s, STief CG, Kölle S (2014) Hyperestrogenism in men - new insights RAMI Biomedical Sciences Annual Meeting [Details]
Dulohery K, Trottmann M, Liedl B, Alba-Alejandre I, Reese S, Kölle S (2014) The effects of testosterone on the functional integrity of the oviduct Conference of the European Society of Human Reproduction and Embryology (ESHRE) [Details]
Kölle S, Liedl B, Alba-Alejandre I, Stief CG, Trottmann M. (2014) The human sperm reservoir: fist proof and characterization by a real-time imaging technique Conference of the European Society of Human Reproduction and Embryology (ESHRE) [Details]
Trottmann M, Stepp H, Liedl B, Reese S, Leeb R, Becker A, Stief CG, Kölle S (2014) Probe-based confocal laser endomicroscopy (pCLE) - a new imaging technique in andrology 66th Conference of the German Society of Urology (DGU) [Details]
Freitag B, Sroka R, Kölle S, Reese S, Becker Aj, Khoder W, Pongratz T, Stief CG, Trottmann M. (2014) Non-invasive alternatives for vasectomy: Intraluminal closure of the vas deferens using laser and Histoacryl 66th Conference of the German Society of Urology (DGU) [Details]
Kölle S (2014) New aspects of semen quality assessment EU AI Vets Meeting [Details]
Kölle S (2014) Role of the oviduct in the management of fertility - new aspects by bio-imaging EU AI Vets Meeting [Details]
Kölle S, Leeb R, Trottmann M (2014) Probe-based confocal laser endomicroscopy (pCLE) as a new diagnostic tool in the bovine female genital tract Conference of the European Society for Animal Reproduction (ESDAR) [Details]
Kölle S (2014) The role of the oviduct in fertility - new aspects by new imaging techniques ÄRE Meeting [Details]
Kölle S (2014) Biosimilars ÄRE Meeting [Details]
Leavy M, Trottmann M, Liedl B, Reese S, Stief C, Kölle S (2014) How does estrogen affect the functional integrity of the testis? European Congress of Andrology [Details]
Kölle S, Trotmmann M (2013) Real new insights in treating infertility Urological Winter Conference [Details]
Kölle S (2013) The spermiogram - basics and pitfalls Urological Winter Conference [Details]
Trottmann M, Schaaf HG, Liedl B, STief CG, Graw M, Braun C, Kölle S (2013) Endoscopy of the vas deferens - a new diagnostic and therapeutic tool in andrology European Congress of Urology [Details]
Trottmann M, Leidl B, Becker Aj, Stief CG, Kölle S (2013) Probe-based confocal laser endomicroscopy (pCLE) - a new imaging technique for in situ localization of vital spermatozoa European Congress of Urology [Details]
Kölle S (2013) Video imaging of eggs and embryos SEED Conference: The Embryo and the Endometrium [Details]
Trottmann M, Stepp H, Becker A, Siegert S, Füllhase C, Gratzke C, Stief C, Kölle S (2012) Probe based confocal laser endomicroscopy (pCLE) - a new technique for optimizing TESE? Congress of the German Urologcial Association (DGU) [Details]
Kölle S, STeif C,Trottmann M (2012) Functional sperm assessment - new aspects gained by live cell imaging Congress of the German Urological Association (DGU) [Details]
Trottmann M, Schaaf HG, Liedl B, Stief C, Graw M, Braun C, Kölle S (2012) Vasoscopy as a new diagnostic and therapeutic tool for dieseases affecting male reproduction 15th European Congress of Sexual Medicine (ESSM) [Details]
Trottmann H, Schaaf HG, Liedl B, Stief C, Graw M, Braun C, Köle S (2012) Vasocscopy - a new diagnostic and therapeutic tool in andrology European Congress of Andrology [Details]
Kölle S. Stepp H, Liedl B, Becker AJ, Gratzke C, Stief CG, Trottmann M (2012) Probe-based confocal laser endomicroscopy (pCLE) - a new dignaostic tool in andrology Eruopean Congress of Urology [Details]
Kölle S, Stepp H, Reese S, Stief C, Liedl B, Trottmann M (2012) Spermatogenesis in the testis as seen by probe-based confocal laser endomicroscopy (pCLE) ICCU Congress [Details]
Trottmann M, Stepp H, Liedl B, Becker A, Füllhase C, Gratzke C, STief CG, Kölle S (2012) Probe based confocal laser endomicroscopy as a new imaging technique in andrology 38th German and Austrian Urological Congress [Details]
Kölle S, Stief C, Trotmann M (2012) New aspects for functional sperm quality assessment 38th German and Austrian Urological Congress [Details]
Kölle S (2011) Gameto- and embryo-maternal interaction in the oviduct - an essential prerequisite for successful pregnancy 3rd CIVTE International Reproductive Congress [Details]
Pachner B, Kölle S (2011) Mechanisms of oocyte and embryo transport in the ex vivo organ culture of the mouse 44th Conference of Physiology and Pathology of Reproduction [Details]
Kölle S, Borkenhagen B, Hatt H, Triller A (2011) The role of progesterone in gameto-maernal interaction - new aspects as seen by live cell imaging GEMINI Conference: Maternal interactions with gametes and embryos [Details]
Kölle S, Achenbach S, Triller A (2011) New aspects of sperm quality assessment 23rd Annual Meeting of the AI Vets [Details]
Kölle S (2011) Physiology and pathology of sperm-oviduct interaction 44th Conference of Physiology and Pathology of Reproduction [Details]
Molsner J, Kölle S (2011) Mechanisms of gamete transport in the oviduct: new insigths using a digital videomicroscopic system 44th Conference of Physiology and Pathology of Reproduction [Details]
Ölschläger V, Kölle S (2011) Influence of PGF2alpha and GnRH on gameto-maternal interaction in vitro 44th Confrerence of Physiology and Pathology of Reproduction [Details]
Triller A, Hatt H, Tschulenk W, Kölle S (2011) Chemosensoric communication between sperm and oocyte: How do the sperm find the oocyte? 44th Conference of Physiology and Pathology of Reproduction [Details]
Molsner J, Tschulenk W, Kölle S (2011) Ultrastructural investigations on gameto-maternal interaction in the oviduct 44th Conference of Physiology and Pathology of Reproduction [Details]
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Honours and Awards

Year: 2012.
Title: Society for the Study of Reproduction (SSR): Top scientific pictures 2012

Year: 2010.
Title: Award for one of the most frequently downloaded papers in 2010

Year: 1999.
Title: Young Scientist Award

Year: 1998.
Title: Scholarship

Year: 1997.
Title: Young Scientist Award of the Society of Histochmistry

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Patents

Patent EP 2784512A1 : New technique for fertility assessment of ejaculates in bulls

Committees

Committee : RDC meeting

Education

Year 1992 Institution:
Qualification: Other Subject: PhD and Habilitation, Specialization in Anatomy

Languages

Spanish:

Latin:

French:

English:

German:

Journals Edited

Reproduction In Domestic Animals: Reviewer.

Journal Of Urology: Reviewer.

Reproductive Biomedicine Online: Reviewer.

Biology Of Reproduction: Reviewer.

Internal Collaborators

Dr. Tom Walsh, Mater Hospital, Dublin

Dr. Edgar Mocanu, Rotunda Hospital, Dublin

Mrs. Geraldine Emerson, Clane Infertility Clinic

External Collaborators

Prof. Christian Stief, School of Medicine, University of Munich

Dr. Matthias Trottmann, School of Medicine, University of Munich

Dr. Irene Alba-Alejandre, School of Medicine, University of Munich

Dr. Sven Reese, School of Veterinary Medicine, University of Munich

Prof. William Ledger, Women`s Hospital, University of Sydney

Teaching Philosophy

Prof. Koelle`s teaching is focused on clinically applied functional anatomy according to the requirements of modern medicine. By correlating topography and imaging techniques (radiography, endoscopy, ultrasonography, MRT) her teaching is aimed to the students obtaining a deep understanding of anatomy and gaining enthusiasm for this fascinating subject.

Modules Coordinated

201700 ANAT20160 Human Anatomy: GI/GU Structure

Enhancement of Teaching

Review and Enhancement of Curriculum

Developing as a Teacher

Innovation & Leadership

2014 Establishment of a new live cell imaging technology for in vivo visualization of fertilization and early embryogenesis 2015 Establishment of optical coherence tomography as new diagnostic tool in the female genital tract 2015/2016 Establishment of probe-based confocal endomicroscopy as novel diagnostic tool in andrology and gynecology

Budras KD, Kölle S, Mülling C, Reese S (2012) 'Anatomy of the Head' In: Budras KD, Kölle S, Mülling C, Reese S (eds). Atlas of the Anatomy of the Dog (German). Hannover: Schlüterscher Verlag. [Details]
Kölle S, Glatzel PS (2011) 'Reproduction in the Mare' In: Kölle S, Glatzel PS (eds). Atlas of Ultrasonography in the Horse (German). Hannover: Schlueterscher Verlag. [Details]
Liebich HG, Kölle S (2010) 'Female Reproductive Organs' In: Liebich HG, Kölle S (eds). Functional Histology of Domestic Animals and Birds (German). Stuttgart, Germany: Schattauer Verlag. [Details]
Kölle S, Wehrend A (2010) 'Pregnancy and Birth' In: Kölle S, Wehrend A (eds). Neonatology in the Dog (German). Hannover, Germany: Schlueterscher Verlag. [Details]
Sinowatz F, Kölle S, Palma GA (2001) 'E structura y funcion de la zona pelucida' In: Sinowatz F, Kölle S, Palma GA (eds). Botecnologia de la Reproduccion (Spanish). Balcarce, Argentina: INTA. [Details]
Kölle S, Sinowatz F (2001) 'Microscopia electronica de embriones producidos in vitro' In: Kölle S, Sinowatz F (eds). Biotecnologia de la Reproduccion (Spanish). Balcarce, Argentina: INTA. [Details]
Sinowatz F, Schams D, Plath A, Kölle S (2001) 'Expression and localization of growth factors during mammary gland development' In: Sinowatz F, Schams D, Plath A, Kölle S (eds). Biology of the Mammary Gland. New York: Kluwer Academic/Plenum Publishers. [Details]
Plendl J, Kölle S, Sinowatz F (1996) 'Non-neoplastic lesions of blood vessels in the aging mouse' In: Plendl J, Kölle S, Sinowatz F (eds). Pathobiology of the Aging Mouse. Washington: ILSI Press. [Details]
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