Professor Suzanne Jarvis

Research

Professor Suzi Jarvis DPhil BA

Contact Details

Title	Director
Address	Innovation Academy 1st Floor Ucd Research Belfield Campus
Telephone:	01-7164042
Email:	ei.dcu@ymedaca.noitavonni
Homepage:	Web Page

Title	Professor of Biophysics
Address	Conway Institute of Biomolecular & Biomedical Research Belfield Campus
Telephone:	01-7166780
Fax:	01-7166777
Email:	ei.dcu@sivraj.izus
Homepage:	Web Page

Biography:

Suzi Jarvis graduated from the University of Oxford with a BA in Physics and a Kodak sponsored DPhil in Materials. This was followed by postdoctoral fellowships in Japan at the Joint Research Center for Atom Technology, Tsukuba, before moving on to a staff position at the Nanotechnology Research Institute, also in Tsukuba. During her time in Japan, Suzi co-founded the International Nanotribology Forum, whose mission is to promote the dissemination of nanotribology research with the inclusions of colleagues from developing nations. Suzi moved to Ireland in July 2002 with funding from Science Foundation Ireland to become a Research Professor in the School of Physics at Trinity College Dublin. During her time at Trinity she was one of the founding Principal Investigators at the Centre for Research and Adaptive Nanostructures and Nanodevices. Suzi is currently Professor of Biophysics in the School of Physics, University College Dublin and is based in the Conway Institute for Biomolecular and Biomedical Research. Suzi runs a multidisciplinary team ranging from electrical engineers to botanists. The underlying theme to all her projects is to understand, manipulate and ultimately utilize the function of biomolecules. The group has particular strengths in the development and application of novel atomic force microscopy techniques, especially in the liquid environment.

Research Interests

Suzi Jarvis runs a multidisciplinary team pursuing a number of research areas at the interface between electrical engineering, mathematics, physics, chemistry, biology, and botany. The underlying theme to all her projects is to understand, manipulate, and ultimately utilize the function of molecules at the nanometer scale. The group has particular strengths in the development and application of novel atomic force microscopy techniques, particularly in the liquid environment. One of the groups’ major goals is to make a conceptual advance in understanding the role of water in biological function, as this would constitute a major contribution across many fields of science. More details of her research can be found on http://www.nanofunction.org.

Notable Achievements
1990 - 1993: Development of first magnetic force controlled atomic force microscope

1999 - 2000: Development of first frequency modulation atomic force microscope in liquid and its application to the measurement of water structure

2006 - 2007: Achievement: Highest demonstrated resolution on a biological sample under physiological conditions (90 pm lateral resolution)

Research Projects

Sponsor : Science Foundation Ireland (SFI)
Title : The Function of Nanoscale Complex Systems
Start Date / End Date : 01-DEC-07 / 31-DEC-12

Sponsor : Science Foundation Ireland (SFI)
University College Dublin (UCD)
Title : CONFOCAL-AFM TIRF-MICROSCOPE
Start Date / End Date : 01-DEC-07 / 30-APR-10

Sponsor : Royal Irish Academy (RIA)
Title : Molecular Level structure and mechanics of engineered bacterial adhesives
Start Date / End Date : 01-JAN-08 / 31-DEC-11

Sponsor : Science Foundation Ireland (SFI)
Title : International Conference on Bioengineering & Nanotechnology
Start Date / End Date : 01-APR-08 / 30-SEP-08

Sponsor : Irish Research Council for Science Engineering and Technology (IRCSET)
Title : Water based lubricants: theory and experiments
Start Date / End Date : 01-JUN-08 / 31-MAY-11

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Book Chapters

S.P. Jarvis, J.E. Sader and T. Fukuma; (2008) 'Frequency and phase modulation AFM in liquids' In: B. Bhshan, H. Fuchs and M. Tomitori (eds). Applied Scanning Probe Methods VIII. Germany: Springer Verlag. [Details]

T. Fukuma and S P Jarvis; (2009) 'Biological applications of FM-AFM in liquid environments' In: Noncontact Atomic Force Microscopy. London: Springer Verlag. [Details]

Peer Reviewed Journals

McGarry, JG,Maguire, P,Campbell, VA,O'Connell, BC,Prendergast, PJ,Jarvis, SP; (2008) 'Stimulation of nitric oxide mechanotransduction in single osteoblasts using atomic force microscopy'. Journal of Orthopaedic Research, 26 :513-521. [DOI] [Details]

Mostaert, A.S., Crockett, R., Kearn, G., Cherney, I., Gazit, E., Serpell, L.C. and Jarvis, S.P.; (2009) 'Mechanically functional amyloid fibrils in the adhesive of a marine invertebrate as revealed by Raman spectroscopy and atomic force microscopy'. Archives of Histology and Cytology, 72 (4/5):199-207.

[DOI] [Details]

Murray, NS,Jarvis, SP,Gunnlaugsson, T; (2009) 'Luminescent self-assembly formation on a gold surface observed by reversible 'off-on' switching of Eu(III) emission'. Chemical Communications, :4959-4961. [DOI] [Details]

Kilpatrick, JI,Gannepalli, A,Cleveland, JP,Jarvis, SP; (2009) 'Frequency modulation atomic force microscopy in ambient environments utilizing robust feedback tuning'. Review of Scientific Instruments, 80 . [DOI] [Details]

J.I. Kilpatrick, A. Gannepalli, J. P. Cleveland and S. P. Jarvis; (2009) 'Frequency modulation atomic force microscopy in ambient environments utilizing robust feedback tuning'. Review of Scientific Instruments, 80 . [Details]

Mostaert, A.S., Giordani, C., Crockett, R., Karsten, U., Schumann, R. & Jarvis, S.P.; (2009) 'Characterisation of amyloid nanostructures in the natural adhesive of unicellular subaerial algae'. The Journal of Adhesion, 85 :465-483. [DOI] [Details]
Loh, SH,Jarvis, SP; (2010) 'Visualization of Ion Distribution at the Mica-Electrolyte Interface'. Langmuir, 26 :9176-9178. [DOI] [Details]
Ferber, UM,Kaggwa, G,Jarvis, SP; (2011) 'Direct imaging of salt effects on lipid bilayer ordering at sub-molecular resolution'. European Biophysics Journal With Biophysics Letters, 40 :329-338. [DOI] [Details]
Sheikh, KH,Giordani, C,Kilpatrick, JI,Jarvis, SP; (2011) 'Direct Submolecular Scale Imaging of Mesoscale Molecular Order in Supported Dipalmitoylphosphatidylcholine Bilayers'. Langmuir, 27 :3749-3753. [DOI] [Details]
Kelly, GM,Kilpatrick, JI,van Es, MH,Weafer, PP,Prendergast, PJ,Jarvis, SP; (2011) 'Bone cell elasticity and morphology changes during the cell cycle'. Journal of Biomechanics, 44 :1484-1490. [DOI] [Details]
Fukuma, T., Mostaert, A. S., Serpell, L. C., Jarvis, S. P., ; (2008) 'Revealing molecular-level surface structure of amyloid fibrils in liquid by means of frequency modulation atomic force microscopy'. Nanotechnology, 19 (38). [Details]
McGarry, J. G., Maguire, P., Campbell, V. A., O'Connell, B. C., Prendergast, P. J., Jarvis, S. P., ; (2008) 'Stimulation of nitric oxide mechanotransduction in single osteoblasts using atomic force microscopy'. Journal of Orthopaedic Research, 26 (4):513-521. [Details]
Kaggwa, G. B., Kilpatrick, J. I., Sader, J. E., Jarvis, S. P., ; (2008) 'Artifact-free dynamic atomic force microscopy reveals monotonic dissipation for a simple confined liquid'. Applied Physics Letters, 93 (1). [Details]
Maguire, P., Kilpatrick, J. I., Kelly, G., Prendergast, P. J., Campbell, V. A., O'Connell, B. C., Jarvis, S. P., ; (2007) 'Direct mechanical measurement of geodesic structures in rat mesenchymal stem cells'. HFSP Journal, 1 (3):181-191. [Details]
Fukuma, T, Higgins, MJ, Jarvis, SP, ; (2007) 'Direct imaging of individual intrinsic hydration layers on lipid bilayers at Angstrom resolution'. Biophysical Journal, 92 :3603-3609. [Details]
Mostaert, AS, Jarvis, SP, ; (2007) 'Beneficial characteristics of mechanically functional amyloid fibrils evolutionarily preserved in natural adhesives'. Nanotechnology, 18 . [Details]
Fukuma, T, Higgins, MJ, Jarvis, SP, ; (2007) 'Direct imaging of lipid-ion network formation under physiological conditions by frequency modulation atomic force microscopy'. Physical Review Letters, 98 . [Details]
Farrell, AA, Kay, ER, Bottari, G, Leigh, DA, Jarvis, SP, ; (2007) 'The effect of solvent upon molecularly thin rotaxane film formation'. Applied Surface Science, 253 :6090-6095. [Details]
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Patents

Patent 7851434 : Amyloid and amyloid-like structures

Conference Contributions

Mostaert, A. S., Higgins, M. J., Karsten, U., Schumann, R., Rindi, F. and Jarvis, S. P.; (2005) Unraveling the mechanical role of proteins in natural algal adhesives by atomic force microscopy. [Oral Presentation], European Life Scientist Organization Meeting, Dresden, Germany , 03-SEP-05 - 06-SEP-05.

Mostaert, A. S., Fukuma, T. & Jarvis, S. P. ; (2006) Amyloid fibrils in natural adhesives. [Poster Presentation], US-Ireland R&D Partnership Workshop, Belfast, Northern Ireland , 23-OCT-06 - 24-OCT-06.

Mostaert, A. S. and Jarvis, S. P. ; (2006) The discovery of amyloid fibrils in natural adhesives. [Poster Presentation], Federation of American Societies for Experimental Biology Summer Research Conference, Protein Misfolding and Aggregation, Snowmass, Colorado, USA , 10-JUN-06 - 15-JUN-06.

Mostaert, A. S., Fukuma, T. and Jarvis, S. P.; (2006) Self-assembled nanostructures in nature and routes to biomimicry. [Poster Presentation], International Conference on Nanoscience and Technology, Basel, Switzerland , 30-JUL-06 - 04-AUG-06.

Jarvis, SP; (2007) Conference. [Invited Oral Presentation], Hoi An Discussions, Hoi An, Vietnam , 26-MAR-07 - 30-MAR-07.

Jarvis, SP; (2007) Workshop. [Invited Oral Presentation], Carbon Nanotubes Workshop, Wollongong, Australia , 15-MAR-07 - 16-MAR-07.
Jarvis, SP; (2007) Workshop. [Invited Oral Presentation], Kanazawa Workshop on Atomic Force Micorscopy, Kanazawa, Japan , 15-JAN-07 - 19-JAN-07.
Mostaert, A. S., Fukuma, T. and Jarvis, S. P. ; (2007) Investigating the mechanical function of self-assembled nanostructures in natural adhesives. [Oral Presentation], Advanced Materials and Nanotechnology, Wellington, New Zealand , 11-FEB-07 - 16-FEB-07.
Jarvis, SP; (2007) Symposium. [Invited Oral Presentation], ESF-EMBO Symposium, Biological Surfaces and Interfaces, Sant Feliu de Guixois, Spain , 01-JUL-07 - 06-JUL-07.
Jarvis, SP; (2007) Conference. [Invited Oral Presentation], International Nano Student Conference (INASCON), Silkeborg, Denmark , 07-JUL-07 - 09-JUL-07.
Jarvis, SP; (2007) Conference. [Invited Oral Presentation], Trends in Nanotechnology 2007, San Sebastian, Spain , 06-SEP-07 - 07-SEP-07.
Mostaert, A. S. and Jarvis, S. P. ; (2007) Exploring the nanomechanical properties of amyloid fibrils in natural adhesives with atomic force microscopy. [Oral Presentation], 31st Microscopy Society of Ireland Meeting, Limerick, Ireland , 22-JUL-07 - 24-JUL-07.
Mostaert, A. S. and Jarvis, S. P. ; (2007) Mechanically functional amyloid structures in natural adhesives. [Poster Presentation], AFM Biomed Conference, Barcelona, Spain , 18-APR-07 - 19-APR-07.
Jarvis, SP; (2007) Conference. [Invited Oral Presentation], 2nd Annual Conference on the Physics, Chemistry and Biology of Water, Vermont, USA , 17-OCT-07 - 22-OCT-07.
Mostaert, A. S. and Jarvis, S. P. ; (2007) Mechanically functional amyloid fibrils in natural adhesives as a target for biomimicry. [Oral Presentation], Bioinspired Nanotechnologies for Smarter Products, Institute of Nanotechnology, London, UK , 20-MAR-07 - 21-MAR-07.
Jarvis, SP; (2008) Invited Seminar. [Invited Lecture], Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland , 16-MAY-08 - 16-MAY-08.
Jarvis, SP; (2008) Invited seminar. [Invited Lecture], National Physical Laboratory, Teddington, UK , 12-MAY-08 - 12-MAY-08.
Jarvis, SP; (2008) Invited seminar. [Invited Lecture], University of Leeds, Leeds, UK , 07-MAR-08 - 07-MAR-08.
Jarvis, SP; (2008) Invited seminar. [Invited Lecture], Asylum Research, Santa Barbara, USA , 08-FEB-08 - 08-FEB-08.
Jarvis, SP; (2008) Invited seminar. [Invited Lecture], Swiss Federal Institute of Technology (ETH), Zurich, Switzerland , 28-JAN-08 - 28-JAN-08.
Jarvis, SP; (2008) Invited seminar. [Invited Lecture], University of Limerick, Limerick, Ireland , 10-JAN-08 - 10-JAN-08.
S P Jarvis; (2008) Conference. [Invited Oral Presentation], UK SPM 2008, London , 25-JUN-08 - 26-JUN-08.
S P Jarvis; (2008) Conference. [Invited Oral Presentation], Scanning Probe Microscopy in Life Sciences, Berlin , 07-OCT-08 - 09-OCT-08.
S P Jarvis; (2008) Conference. [Invited Oral Presentation], Institute of Physics, Surface and Interface Science Meeting, Fribourg, Switzerland , 25-JAN-08 - 25-JAN-08.
S P Jarvis; (2008) Conference. [Invited Oral Presentation], Materials Research Society Spring Meeting, San Francisco, USA , 23-MAR-08 - 27-MAR-08.
S P Jarvis; (2008) Meeting. [Invited Oral Presentation], EC-US Task Force on Nanobiotechnology, Ispra, Italy , 02-JUN-08 - 04-JUN-08.
S P Jarvis; (2008) Conference. [Invited Oral Presentation], International Conference on Bioengineering and Nanotechnology, Dublin , 22-JUL-08 - 24-JUL-08.
Suzi Jarvis; (2009) Ångstrom-resolution imaging of biological materials and their aqueous environments. [Invited Lecture], American Chemical Society Spring Meeting, Salt Lake City , 19-APR-09 - 24-APR-09.
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Education

Year 1990 Institution: Oxford University, UK
Qualification: BA Subject:

Year 1993 Institution: Oxford University, UK
Qualification: DPhil Subject:

Reviews

The Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology: Reviewer.

Physical Review Letters: Reviewer.

Nanotechnology: Reviewer.

Langmuir: Reviewer.

Journal Of Molecular Biology: Reviewer.

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Other Activities

Grant reviewer:

The Royal Society, UK
Swiss National Science Foundation
BBSRC, UK

External Collaborators

I currently have a RIA funded collaboration with Dr Paul Barker, Chemistry Department, University of Cambridge to work on the molecular level structure and mechanics of engineered bacterial adhesive. I also have a three year research project funded by the ESF/IRCSET to work with Prof. Nicholas Spencer, ETH, Zurich and Prof. Michael Urbach and Prof. Joseph Klafter, Tel Aviv University to work on aqueous lubricants. I co-supervise students with Prof. Paddy Prendergast, TCD and Dr. Patrick McGarry at NUI Galway, both in the area of single cell mechanics.

Teaching Interests

Current Postgraduate Students

Baiyun Liu, Doctor of Philosophy (PhD) - Thesis Supervisor

Padraig Keane, Doctor of Philosophy (PhD) - Thesis Supervisor

Timothy Brosnan, Doctor of Philosophy (PhD) - Thesis Supervisor

Modules Taught

201100 IA40170 Innovation Academy: Inspiration

201100 IA40110 Innovation Academy: Creation

201100 IA40150 Innovation Academy: Activation

201100 IA40120 Innovation Academy: Recognition

201100 IA40240 Innovation Academy: Commercialisation

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Sponsor : Science Foundation Ireland (SFI) Title : Development of an Active Biomechanical Model to Analyse Experimentally Observed Cell Behaviour in Response to Mechanical Stimuli Start Date / End Date : 01-SEP-08 / 31-AUG-11
Sponsor : Irish Research Council for Science Engineering and Technology (IRCSET) Title : Development of high speed atomic force microscopy for biological applications Start Date / End Date : 01-SEP-09 / 31-AUG-12
Sponsor : University College Dublin (UCD) Title : AFM/Confocal Project Start Date / End Date : 15-SEP-10 / 31-DEC-10
Sponsor : Higher Education Authority (HEA) Title : PRTLI 5: i-Academy Start Date / End Date : 01-MAR-11 / 29-FEB-16
Sponsor : Higher Education Authority (HEA) Title : PRTLI 5: Nanoremedies - Split Accounts Start Date / End Date : 01-MAR-11 / 28-FEB-15
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Journal Of Applied Physics: Reviewer.
Review Of Scientific Instruments: Reviewer.
Biophysical Journal: Reviewer.
Applied Physics Letters: Reviewer.
Nature Nanotechnology: Reviewer.
Nature Physics: Reviewer.
Nature: Reviewer.
Science: Reviewer.
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200800 PHYC40490 Physics: Biomimicry
200800 PHYC40440 Physics: Atomic Force Microscopy
200800 PHYC40430 Physics: Nanomechanics
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