Reseach Opportunities in Tetrapyrrole Chemistry and Oesophagel Cancer Research

Post Title:       Postdoctoral/Graduate Researchers and PhD Studentships in                        Chemistry and Molecular Medicine
School:            School of Chemistry, SFI Tetrapyrrole Laboratory
Closing Date:  30.09.2007 or until filled
Salary:            Postdoctoral Researcher Level 2 scale, up to point 6 €46,043

Applications are invited for post doctoral positions and Ph.D. studentships in Molecular Medicine to work on the use of tetrapyrrole-based photosensitizers for the development of efficient treatment and indication protocols for oesophageal cancer. The position is funded by a Health Research Board Translational Research Award to a collaborative group from medicine, pharmacy and chemistry. The postdoctoral position will be for up to three years in the first instance, with the possibility for a further two years. The work will involve chemical and cell biological studies on photosensitizers and drug development. The candidate will be expected to supervise a small group of chemistry and biochemistry postgraduates and manage a laboratory at the DMMC on the St. James site of TCD. Appointed candidates will report to Prof. Mathias Senge.
For the postdoctoral position candidates ideally should have prior postdoctoral experience and meet the following requirements:

  1. Ph.D. in a related area, i.e. chemistry, biochemistry of molecular medicine.
  2. Previous experience with drug development and cell biological testing, oesophageal cancer, imaging, preferably in PDT.
  3. Excellent interpersonal skills and the ability to work collaboratively both within the research group and external collaborators.
  4. Ability to develop new research ideas and grant proposals; the successful candidate will be encouraged to apply for their own fellowships.

For the Ph.D. studentships, a first or upper second class degree in chemistry, biochemistry or molecular medicine is required.

Applications are also invited for post doctoral positions and 2 Ph.D. studentships in Organic Chemistry. Research areas here broadly involve the development of new synthetic methods and functionalization reactions for tetrapyrroles. For the postdoctoral position, candidates should have prior research experience in porphyrin chemistry and/or the structural characterization of natural products and will be expected to work independently guiding a small team of PG researchers. An interest in biochemistry or crystallography would be beneficial.

Applications with a full CV and the names and e-mail addresses of two referees should be sent to: Prof. Dr. Mathias O. Senge, SFI Tetrapyrrole Laboratory, School of Chemistry, Trinity College Dublin, Dublin 2, Ireland, phone: 00353-1-896-8537, e-mail:, internet: