Pharmaceuticals

Project Title Contact
Holographic Inspection of Bio-Pharmaceutical Processes: Optical Monitoring of Cell Growth In the Production Line  Prof John Sheridan
Synthesis and Biological Evaluation of Bioorganometallic Antibiotics  Dr Matthias Tacke
Synthesis and Biological Evaluation of Bioorganometallic Anticancer Drugs  Dr Matthias Tacke
Application of the catalytic asymmetric alpha-arylation of ketones in total synthesis  Prof Pat Guiry
Synthesizing specific inhibitors of Falcipain 3 a drug target for treating malaria  Prof Paul Malthouse
Synthesizing specific glyoxal inhibitors of Urokinase Plasminogen Activator(uPA) a drug target for treating breast cancer  Prof Paul Malthouse
Determining warhead potency with protease inhibitors  Prof Paul Malthouse
Synthesizing isotopically enriched protease inhibitors and enzymes for NMR studies of protease - inhibitor interactions  Prof Paul Malthouse
Development of skincare products from frog skin peptides Dr Chandralal Hewage
NMR and molecular modeling studies of incretin hormones Dr Chandralal Hewage
Structural studies of antimicrobial peptides

Dr Chandralal Hewage
Natural products for diabetic therapy Dr Chandralal Hewage
Diabetic Kidney Disease  Dr Tara McMorrow
Renal Toxicology and Toxicity Testing Dr Tara McMorrow
Catalytic Asymmetric Grignard reaction  Prof Declan Gilheany
P-Stereogenic components of ProTide drugs  Prof Declan Gilheany
Alternative, in vitro testing strategies for screening pharmaceuticals and chemicals for potential developmental toxicity: New horizons with a human induced pluripotent stem cell model (iPSTox). Dr Helen Gallagher
Development of Catalysts for Stereoselective Glycosylations Dr Eoghan McGarrigle
Organocatalysts for the Synthesis of 2-DeoxySugars Dr Eoghan McGarrigle
Differential hypoxia signaling in breast cancer: potential therapeutic target Dr Alex Cheong
Molecular simulation studies of protein-ligand binding and nanomedicine via structure-based drug design  Dr Niall English
Development of new photodynamic therapeutic agents. Prof Donal O'Shea