Case-cohort analysis of genetic risk factors in a large follow-up study for cardiovascular disease

Speaker: Dr. Patrick Dicker (Royal college of surgeons)

Time: 4:00PM
Date: Fri 10th November 2006

Location: Mathematical Sciences Teaching Room

MORGAM is a European prospective study of risk and genetics of cardiovascular disease (CAVD) in over 30,000 people. Platelets are known to have a role in cardiovascular disease and genetic variants associated with platelet function, along with risk-factor phenotypes, were assessed for CAVD risk. Genotyping was performed in a case-cohort setting for multiple endpoints and analysed using weighted partial-likelihood (Cox) model and Bayesian full-likelihood

(This talk is part of the Statistics and Actuarial Science series.)