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Marie Curie Molecular Neuroimmunology PhD Programme

University College Dublin - An Coláiste Ollscoile, Baile Ảtha Cliath

 

 

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Neuroimmunology Module Schedule & Outline

 

Course Organisers: Dr A Campos-Torres, Dr C O’Connor

Module Co-ordinator: Dr C O’Connor (clare.oconnor@ucd.ie)

 

Weekly sessions: 9:30 am - 12:30 pm on Wednesdays, from April 11th to June 27th

Date & Time

Session & Topic

Co-ordinator

April 11th
L1  09.30 – 10.45
L2  11.00 – 12.30
1. Neuroimmunology: Elements of the  System(s)
 - Introduction &  Brief Overview of the elements involved in bidirectional 
   communication between  the immune and nervous systems – Clare  O’Connor
 - Homeostasis and  Mechanisms of inflammation in the CNS – Antonio Campos-Torres 

C O’Connor

 

April 18th
L1  09.30 – 10.45
L2  11.00 – 12.30
2.  Introduction to Neuropathology and Neuroinflammation    
 - Neuron-glia interactions – Gethin McBean 
 - Principles of Neuroinflammation and  Neuropathology and 
   Glial cell biology – Antonio Campos-Torres

A Campos-Torres

April 25th
L1  09.30 – 10.45
L2  11.00 – 12.30
3. Neuroendocrine modulation of the  immune response
- Neurotransmitter modulation of leukocyte  function – Clare O’Connor
- Neuroendocrine modulation of the mucosal  immune system – Ann Hopkins

C O’Connor

May 2nd
L1  09.30 – 10.45
L2  11.00 – 12.30
4. Immune system homeostasis on the CNS
   - Innate  and adaptive immune responses in neuroprtection and 
     neurodegeneration - Complement cascade activation - Antonio Campos-Torres
   - Role of regulatory T cells in the CNS - Antonio Campos-Torres

A Campos-Torres

 

May 9th
L1  09.30 – 10.45
L2  11.00 – 12.30
5. Mechanisms of neuroprotection  and injury in the CNS
- Cytokines and Chemokines – Paola Moderna 
- Hypoxia & Stroke - Cormac Taylor 

A Campos-Torres

 

May 16th
L1  09.30 – 10.45
L2  11.00 – 12.30
6. Signalling  pathways and transcription factors underlying the 
inflammatory response
- TIR family, MAPK – Paola Moderna
- NFκB, IRF3, AP1 – Bryan Griffin

A Campos-Torres

May 23rd
L1  09.30 – 10.45
L2  11.00 – 12.30
7. Neuroimmune modulation of  neuronal function 
   - Inflammatory mediators and ion channels - Caroline Herron
   - Modulation of neurotransmitters receptors  function by cytokines - John O’Connor

A Campos-Torres

May 30th
L1  09.30 – 10.45
L2  11.00 – 12.30
8. Neuropathology and  neuroinflammation from basic science to clinical issues I 
- Alzheimer’s disease – Dominic Walsh
- ALS & Huntington’s – Gethin McBean

A Campos-Torres

June 6th
L1  09.30 – 10.45
L2  11.00 – 12.30
9. Neuropathology and  neuroinflammation from basic science to clinical issues II - 
- Multiple Sclerosis - Michelle Armstrong
- Therapeutic strategies & Drug  discovery – William O’Connor

A Campos-Torres

 

June 13th
L1  09.30 – 10.45
L2  11.00 – 12.30
10. Examples of Neuroendocrine  modulation of inflammatory diseases- 
- Arthritis (autoimmune) - Evelyn Murphy
- Type I Diabetes (metabolic) - Philip Newsholme

C O’Connor

June 20th
L1  09.30 – 10.45
L2  11.00 – 12.30
11. Immunomudulation and Behaviour 
- Acute and chronic effects of stress on  the immune system – Philippe Newsholme
- A role for immune signals in cognitive  function and behaviour – Keith Murphy

C O’Connor

June 27th
L1  09.30 – 10.45
L2  11.00 – 12.30
12. Clinical Overview and  Perspective on therapeutic strategies 
- Clinical overview of neurodegenerative  diseases – Gavin Rush
- Clinical perspectives on current and developping strategies for 
  neuroimmunological diseases - Gavin Rush

 

     
 

C O’Connor