Research

Recent Publications

2012

Brayden, D.J., Bzik, V., Lewis, A.L. & Illum, L (2012) 'CriticalSorb promotes permeation of flux markers across isolated rat intestinal mucosae and Caco-2 monolayers'. Pharmaceutical Research.

Bzik, V., Medani, M., Baird, A. W., Winter, D., Brayden, D.J. (2012) 'Mechanisms of Action of Zinc on Intestinal Epithelial Electrogenic Ion Secretion: Insights into its Anti-Diarrheal Actions'. Journal of Pharmacy and Pharmacology, 64 (5):644-653.

Electromechanical properties of dried tendon and iso-electrically focused collagen hydrogels, Denning, D., Abu-Rub, M.T., Zeugolis, D.I., Habelitz, S., Pandit, A., Fertala, A., and Rodriguez, B.J., Acta Biomaterialia, 8, 3073-3079, (2012).

Fields, C., Mallee, P., Muzard, J., Lee, G.U. (2012). Isolation of Bowman-Birck-Inhibitor from Soybean Extracts using Novel Peptide Probes and High Gradient Magnetic Separation.’ Journal of Food Chemistry, in press.

Muzard, J., Platt, M., Lee, G.U. (2012). M13 Bacteriophage-Activated Superparamagnetic Beads for Affinity Separation. Small, in press.

Photoreduction of SERS-Active Metallic Nanostructures on Chemically Patterned Ferroelectric Crystals. Carville, N.C., Manzo, M., Damm, S., Castiella, M., Collins, L., Denning, D., Weber, S.A.L., Gallo, K., Rice, J.H., and Rodriguez, B.R., ACS Nano. Accepted July 2012, in press. See here for full text: ACS Nano 2012.

Platt, M., Willmott, G., and Lee, G.U. (2012). Resistive Pulse Sensing of Analyte-Induced Multicomponent Rod Aggregation Using Tunable Pores. Small, DOI: 10.1002/small.201200058

Sandin P, Fitzpatrick LW, Simpson JC & Dawson KA (2012). High-speed imaging of Rab family small GTPases reveals rare events in nanoparticle trafficking in living cells. ACS Nano 6:1513-1521.

Simpson JC, et al. (2012). Genome-wide RNAi screening identifies human proteins with a function in the early secretory pathway. Nature Cell Biology, in press.

Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R. (2012) 'Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway'. Nature Cell Biology.

Singan VR, Handzic K, Curran KM, Simpson JC (2012) 'A method for improved clustering and classification of microscopy images using quantitative co-localization coefficients'. BMC research notes, 5 (1).

Stability enhancement of an atomic force microscope for long-term force measurement including cantilever modification for whole cell deformation, Jarvis, S., and McGarry, P. 2012. (submitted to Review of Scientific Instruments).

2011

Bexiga MG, Varela JA, Wang F, Fenaroli F, Salvati A, Lynch I, Simpson JC & Dawson KA (2011). Cationic nanoparticles induce caspase 3-, 7- and 9-mediated cytotoxicity in a human astrocytoma cell line. Nanotoxicology 5:557-567.

Li, P., Mahmood, A., Lee, G.U. Flow-enhanced Nonlinear Magnetophoresis for High-resolution Bioseparation. Langmuir. 2011: 27(10) 6496-6503.

Moore HM, Bai B, Boisvert FM, Latonen L, Rantanen V, Simpson JC, Pepperkok R, Lamond AI, Laiho M (2011) 'Quantitative Proteomics and Dynamic Imaging of the Nucleolus Reveal Distinct Responses to UV and Ionizing Radiation'. Molecular & Cellular Proteomics, 10 :M111.009241-1-M111.009241-15

Ryan SM, Frías JM, Wang X, Sayers CT, Haddleton DM, Brayden DJ; (2011) 'PK/PD modelling of comb-shaped PEGylated salmon calcitonin conjugates of differing molecular weights'. Journal of Controlled Release, 149 (2):126-132

Singan VR, Jones TR, Curran KM & Simpson JC (2011). Dual channel rank-based intensity weighting for quantitative co-localization of microscopy images. BMC Bioinformatics 12:407.

Walsh, E.G., Maher, S., Devocelle, M., O'Brien, P.J., Baird, A.W., Brayden, DJ.; (2011) 'High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs'. Peptides, 32 (8):1764-1773.

Willmott, G., Platt, M., Lee, G.U. Resistive Pulse Sensing of Magnetic Beads and Supraparticle Structures using Tunable Pores. Biomicrofluidics. 2011: 6(1).

Zhang, Y., DaSilva, M., Shall, B., Doyle, G., Zerulla, D., Sands, T.D., Lee, G.U. Magnetic Manipulation and Optical Imaging of an Active Plasmonic Single-Particle Fe-Au Nanorod. Langmuir. 2011: 27(24) 15292-15298.