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CSCB Researchers Discover Potential Chemotherapy Agent for Treating Kidney Cancer

 


Renal cell cancer is the most common type of kidney cancer and in Ireland 266 new cases and 140 cancer deaths are reported per year.1 It can be treated in a number of ways depending on the stage of the cancer and the patient's age and health, but thus far it has proved to be very resistant to chemotherapeutic drugs.

Dr Matthias Tacke, a Senior Lecturer at the UCD School of Chemistry and Chemical Biology and a researcher with the Centre for Synthesis and Chemical Biology has been working on known anti-cancer drugs belonging to the titanocene family for five years.

Dr Matthias Tacke with his CSCB research group

Dr Matthias Tacke with his CSCB research group

"Titanocene dichloride, a cytotoxic anti-cancer drug, was found not to be cytotoxic enough in Phase II clinical trials carried out in Germany in 1998," explains Dr Tacke. "We decided to focus our research in UCD on making derivatives of titanocene dichloride, which we hoped would be more efficacious."