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Dr Aifric O'Sullivan graduated from the University of Limerick with a BSc in Sport and Exercise Sciences. From there she moved to the University of Aberdeen to complete an MSc in Human Nutrition and Metabolism and returned to University College Dublin to begin her PhD work in Nutritional Metabolomics. She has extensive experience in exercise and nutrition based human research projects. She has designed and implemented several human interventions that have included nutritional supplements, dietary based weight loss programmes, and exercise interventions, and evaluated results using a variety of analytical approaches including biochemistry, nuclear magnetic resonance (NMR) spectroscopy, statistics, bioinformatics, and metabolomics. As a postdoctoral researcher in UCD she was involved in aspects of the National Phenotype Database (www.ucd.ie/JINGO). In 2011 she began a Postdoc at the University of California, Davis where she continued work to understand the basis for diversity in human responses to diet and lifestyle. In an extension of this work she had the opportunity to examine metabolomic profiles of biofluids from rabies patients, which is informing innovative treatment strategies. While in Davis she expanded her research portfolio applying metabolomic technologies to monitor key dimensions of the early development of infant health. She returned to UCD to take up a position as Lecturer in Human Nutrition and is continuing her research theme with a particular focus on the first 1000 days of life. She is currently involved in AGRIDIET (www.ucc.ie/AGRIDIET), a HEA and Irish Aid collaborative initiative to understand how agriculture impacts on the nutritional status of the members of rural households in areas of high nutritional vulnerability in Ethiopia and Tanzania. |
| My
principal research interests lie in the application of metabolomics in
nutritional sciences. I have made significant progress in two areas of research.
The first involves using metabolomics along with other analytical and statistical
tools to examine variation in response to dietary interventions and identify
metabolic phenotypes associated with specific responses. The direct impact of
this research would see the development of personalised diet and lifestyle
recommendations to improve health status across the population. The second area
of research focuses on infant nutrition. I am currently interested in applying
metabolomic techniques and other strategies to better understand the metabolic implications of a
variety of factors for healthy infant development during the first 1000 days of life; from maternal health status
to early infant exposures, such as feeding practices.
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| O'Sullivan A, Avizonis D, German JB, Slupsky CM. (2012) 'Software Tools for NMR Metabolomics' In: Encyclopedia of Magnetic Resonance. Online: John Wiley & Sons, Ltd. [Details] |
| O'Sullivan A, Balducci D, Paradisi F, Cashman KD, Gibney MJ, Brennan L. (2011) 'Effects of supplementation with vitamin D3 on glucose production pathways in human subjects'. Molecular Nutrition and Food Research, 55 :1018-1025. [DOI] [Details] |
| O'Sullivan A, Gibney MJ, Brennan L. (2011) 'Dietary intake patterns are reflected in metabolomic profiles: potential role in dietary assessment studies'. American Journal of Clinical Nutrition, 93 (2):314-321. [DOI] [Details] |
| O'Sullivan A, Gibney MJ, O'Connor A, Mion B, Kaluskar S, Cashman KD, Flynn A, Shanahan F, Brennan L. (2011) 'Biochemical and metabolomic phenotyping in the identification of a vitamin D responsive metabotype for markers of the metabolic syndrome'. Molecular Nutrition and Food Research, 55 (5):679-690. [DOI] [Details] |
| O'Sullivan A, He X, Sproat-McNiven EM, Mishchuk DO, Hinde K Neill W. Haggarty NW, Lönnerdal B, and Slupsky CM (2012) 'Metabolomic phenotyping validates the infant rhesus monkey as a model of human infant metabolism'. Journal of Pediatric Gastroenterology and Nutrition, . [Details] |
| O'Sullivan A, Willoughby RE, Mishchuk D, Alcarraz B, Cabezas-Sanchez C, Condori RE, David D, Encarnacion R, Fatteh N, Fernandez J, Franka R, Hedderwick S, McCaughey C, Ondrush J, Paez-Martinez A, Rupprecht C, Velasco-Villa A, Slupsky CM (2012) 'Metabolomics of cerebrospinal fluid from humans treated for rabies'. Journal of Proteome Research, . [DOI] [Details] |
| Zivkovic A, Yang J, Georgi K, Hegedus C, Nording M, O'Sullivan A, German JB, Hogg R, Weiss R, Bay C, Hammock, B. (2012) 'Serum oxylipin profiles in IgA nephropathy patients reflect kidney functional alterations'. Metabolomics, 8 (6). [DOI] [Details] | |||||||||
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| O'Connor A, Brennan L, Mion B, O'Sullivan A, Kaluskar S, Cashman KD, Flynn A, Marchesi J, Shanahan F, Gibney MJ. (2010) Effects of probiotic supplementation on gut microbiota composition and immunological markers in healthy volunteers Nutrition Society Summer Meeting [DOI] [Details] |
| O'Sullivan A, Brennan L, Mion B, O'Connor A, Kaluskar S, Cashman KD, Flynn A, Marchesi J, Shanahan F, Gibney MJ (2010) Investigating physiological variation in healthy Irish adults using a combination of traditional techniques and emerging metabolomic technologies Nutrition Society Summer Meeting [DOI] [Details] |
| Year: 2009. Title: Irish Section ICN Bursary 2009 |
| Year: 2009. Title: UCD Seed Funding Scheme |
| Year: 2010. Title: NuGO Week Poster Prize |
| Year: 2012. Title: Nominated for the Award for Excellence in Postdoctoral Research |
| Association: Metabolomics Society, Function/Role: Member |
| Association: The European Nutrigenomics Organisation NuGO, Function/Role: Member |
| Association: Nutrition Society, Function/Role: Registered Nutritionist |
| O'Halloran J, Clegg M, Brennan G, Foley M, Murphy B, O'Sullivan A, Shafat A. (2005) High-concentration sports drinks aid performance. [Poster Presentation], Nutrition Society Summer Meeting, University of East Anglia, UK , 28-JUN-05 - 01-JUL-05. |
| Aifric O'Sullivan (2006) Fatigue during low-carbohydrate dieting in sedentary obese men. [Poster Presentation], Nutrition Society Summer Meeting, University of Aberdeen, Scotland , 03-JUL-06 - 06-JUL-06. |
| Aifric O'Sullivan and Lorraine Brennan (2009) Investigating physiological variation in healthy Irish adults using a combination of traditional techniques and emerging metabolomic technologies. [Poster Presentation], NuGO Week 2009, Montecatini Terme, Italy , 31-AUG-09 - 03-SEP-09. |
| Aifric O'Sullivan (2009) Investigating the effects of vitamin D supplementation on metabolic health parameters in healthy adults. [Poster Presentation], International Congress of Nutrition, Bangkok, Thailand , 04-OCT-09 - 09-NOV-12. |
| Aifric O'Sullivan (2010) NuGo Week 2010. [Poster Presentation], Dietary intake patterns are reflected in metabolomic profiles, Glasgow, Scotland , 31-AUG-10 - 03-SEP-10. |
| Aifric O'Sullivan (2012) Dietary intake patterns are reflected in metabolomic profiles: potential role in dietary assessment studies. [Oral Presentation], The Rank Prize Funds Nutritional Biomarkers: Present Science and Future Opportunities, Cumbria, UK , 20-SEP-10 - 23-SEP-10. | |||||||||
| Aifric O'Sullivan (2012) UC Davis Foods For Health Institute and USDA, ARS, WHNRC Meeting. [Conference Organising Committee Member], Measuring response to food: phenotyping tools and targets, University California, Davis , 08-JUN-12 - 09-JUN-12. | |||||||||
| Aifric O'Sullivan (2012) First International Workshop of the US-Denmark Co-operation. [Conference Organising Committee Member], Diet & Human Health: The inputs to Phenotype, from Genetics to Food Choices, USDA, Washington DC , 30-APR-12 - 01-MAY-12. | |||||||||
| Aifric O'Sullivan (2012) Metabolomics in infant nutrition: metabolic implications of different feeding practices. [Oral Presentation], Metabolomics Society Meeting, Washington, DC , 25-JUN-12 - 28-JUN-12. | |||||||||
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| Employer: Institute of Technology, Carlow Position: Lecturer (part-time) |
| Employer: Institute of Technology, Tralee Position: Lecturer |
| Employer: University College Dublin Position: Lecturer (part-time) |
| Employer: University College Dublin Position: Post-Doctoral Researcher |
| Employer: University College Dublin Position: Lecturer |
| Employer: University California, Davis Position: Post-Doctoral Researcher |
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| Year 2004 Institution: University of Limerick Qualification: BSc (First Class Hons) Subject: Sports and Exercise Science |
| Year 2005 Institution: University of Aberdeen Qualification: MSc (With Distinction) Subject: Human Nutrition and Metabolism |
| Year 2010 Institution: University College Dublin Qualification: PhD Subject: Nutritional Metabolomics |
| Prof. Mike Gibney, UCD Dr. Lorraine Brennan, UCD Dr. Jim Kinsella, UCD Dr. Deirdre O'Connor, UCD |
| Prof. Nora O'Brien, UCC Dr. Nick Chisholm, UCC Dr. Edward Lahiff, UCC Dr. Kathy Glavanis-Grantham, UCC Prof. Bruce German Director, Foods For Health Institute Department of Food Science & Technology University of California, Davis, CA 95616 Asst. Prof. Carolyn Slupsky Department of Food Science & Technology University of California, Davis, CA 95616 Dr. John Newman USDA, ARS Western Human Nutrition Research Center 430 West Health Sciences Drive University of California, Davis, CA 95616 Dr. Charles Stephensen USDA, ARS Western Human Nutrition Research Center 430 West Health Sciences Drive University of California, Davis, CA 95616 |
