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Aifric O'Sullivan

Lecturer/Assistant Professor In Human Nutirion

School Of Agriculture & Food Science
Science Centre - South
Belfield
Dublin 4

Tel: +353 1 7162824
Email: aifric.osullivan@ucd.ie

Biography

Dr Aifric O'Sullivan received a BSc in Sport and Exercise Sciences from the University of Limerick, an MSc in Human Nutrition and Metabolism from the University of Aberdeen and a PhD in Nutritional Metabolomics from University College Dublin.  Dr O'Sullivan joined UCD as an Assistant Professor in Human Nutrition in 2012 from University California, Davis where she was a Postdoctoral researcher within the Foods For Health Institute on US NIH, USDA, and global industry funded research projects. She is a deputy director of the UCD Childhood and Human Development Research Centre and an active member of the UCD Institute of Food and Health.

Dr O'Sullivan's research aims to understand interactions between diet and metabolism that define nutritional phenotypes across the lifespan.  She is PI on the UCD Twin Study exploring the genetic and environmental influences on food choice and metabolomics and leads the nutrition component of the AgriDiet project in Tanzania with the aim to understand agri-nutrition linkages and potential for sustainable interventions towards future food and nutrition security. Much of her research involves the application of metabolomics as a method to explore differential responses to diet, lifestyle and interventions. She teaches at undergraduate and postgraduate levels, has supervised 2 MSc students to completion and has 2 PhD students due to graduate. She is a member of the European Academies Science Advisory Council for Food and Nutrition Security, a member of the board of UCD Volunteers Overseas and a member of the Metabolomics Society, the Nutrition Society (UK) and the European Nutrigenomics Organisation (NuGO).

Professional

Honours and Awards

Year: 2009.
Title: Irish Section ICN Bursary 2009
Year: 2009.
Title: UCD Seed Funding Scheme
Year: 2010.
Title: NuGO Week Poster Prize
Year: 2012.
Title: Nominated for the Award for Excellence in Postdoctoral Research

Associations

Association: Metabolomics Society, Function/Role: Member
Association: The European Nutrigenomics Organisation NuGO, Function/Role: Member
Association: Nutrition Society, Function/Role: Registered Nutritionist
     

Conference Contributions

O'Halloran J, Clegg M, Brennan G, Foley M, Murphy B, O'Sullivan A, Shafat A. (2005) High-concentration sports drinks aid performance. [Poster Presentation], Nutrition Society Summer Meeting, University of East Anglia, UK , 28-JUN-05 - 01-JUL-05.
Aifric O'Sullivan (2006) Fatigue during low-carbohydrate dieting in sedentary obese men. [Poster Presentation], Nutrition Society Summer Meeting, University of Aberdeen, Scotland , 03-JUL-06 - 06-JUL-06.
Aifric O'Sullivan and Lorraine Brennan (2009) Investigating physiological variation in healthy Irish adults using a combination of traditional techniques and emerging metabolomic technologies. [Poster Presentation], NuGO Week 2009, Montecatini Terme, Italy , 31-AUG-09 - 03-SEP-09.
Aifric O'Sullivan (2009) Investigating the effects of vitamin D supplementation on metabolic health parameters in healthy adults. [Poster Presentation], International Congress of Nutrition, Bangkok, Thailand , 04-OCT-09 - 09-NOV-12.
Aifric O'Sullivan (2010) NuGo Week 2010. [Poster Presentation], Dietary intake patterns are reflected in metabolomic profiles, Glasgow, Scotland , 31-AUG-10 - 03-SEP-10.
Aifric O'Sullivan (2012) Dietary intake patterns are reflected in metabolomic profiles: potential role in dietary assessment studies. [Oral Presentation], The Rank Prize Funds Nutritional Biomarkers: Present Science and Future Opportunities, Cumbria, UK , 20-SEP-10 - 23-SEP-10.
Aifric O'Sullivan (2012) UC Davis Foods For Health Institute and USDA, ARS, WHNRC Meeting. [Conference Organising Committee Member], Measuring response to food: phenotyping tools and targets, University California, Davis , 08-JUN-12 - 09-JUN-12.
Aifric O'Sullivan (2012) First International Workshop of the US-Denmark Co-operation. [Conference Organising Committee Member], Diet & Human Health: The inputs to Phenotype, from Genetics to Food Choices, USDA, Washington DC , 30-APR-12 - 01-MAY-12.
Aifric O'Sullivan (2012) Metabolomics in infant nutrition: metabolic implications of different feeding practices. [Oral Presentation], Metabolomics Society Meeting, Washington, DC , 25-JUN-12 - 28-JUN-12.
 

Employment

Employer: Institute of Technology, Carlow
Position: Lecturer (part-time)
Employer: Institute of Technology, Tralee
Position: Lecturer
Employer: University College Dublin
Position: Lecturer (part-time)
Employer: University College Dublin
Position: Post-Doctoral Researcher
Employer: University College Dublin
Position: Lecturer
Employer: University California, Davis
Position: Post-Doctoral Researcher

Education

Year 2004 Institution: University of Limerick
Qualification: BSc (First Class Hons) Subject: Sports and Exercise Science
Year 2005 Institution: University of Aberdeen
Qualification: MSc (With Distinction) Subject: Human Nutrition and Metabolism
Year 2010 Institution: University College Dublin
Qualification: PhD Subject:
         

Publications

 

Book Chapters

O'Sullivan A, Avizonis D, German JB, Slupsky CM. (2012) 'Software Tools for NMR Metabolomics' In: O'Sullivan A, Avizonis D, German JB, Slupsky CM (eds). Encyclopedia of Magnetic Resonance. Online: John Wiley & Sons, Ltd. [Details]
 

Peer Reviewed Journals

O'Sullivan A, He X, McNiven EM, Haggarty NW, Lönnerdal B, Slupsky CM (2013) 'Early diet impacts infant rhesus gut microbiome, immunity, and metabolism'. Journal of Proteome Research, 12 (6):2833-2845. [DOI] [Details]
Smilowitz JT, O'Sullivan A, Barile D, German JB, Lönnerdal B, Slupsky CM. (2013) 'The human milk metabolome reveals diverse oligosaccharide profiles'. Journal of Nutrition, 143 (11):1709-18. [DOI] [Details]
O'Sullivan A, Armstrong P, Schuster GU, Pedersen TL, Allayee H, Stephensen CB, Newman JW (2014) 'Habitual Diets Rich in Dark-Green Vegetables Are Associated with an Increased Response to omega-3 Fatty Acid Supplementation in Americans of African Ancestry'. Journal of Nutrition, 144 (2):123-31. [Details]
O'Sullivan A, He X, McNiven EM, Hinde K, Haggarty NW, Lonnerdal B, Slupsky CM (2013) 'Metabolomic phenotyping validates the infant Rhesus Monkey as a model of human infant metabolism'. Journal of Pediatric Gastroenterology and Nutrition, 56 (4):355-63. [DOI] [Details]
Neal CM, Hunter AM, Brennan L, O'Sullivan A, Hamilton DL, De Vito G, Galloway SD (2013) 'Six weeks of a polarized training-intensity distribution leads to greater physiological and performance adaptations than a threshold model in trained cyclists'. Journal of Applied Physiology, 114 (4):461-471. [DOI] [Details]
O'Sullivan A, Balducci D, Paradisi F, Cashman KD, Gibney MJ, Brennan L. (2011) 'Effects of supplementation with vitamin D3 on glucose production pathways in human subjects'. Molecular Nutrition and Food Research, 55 :1018-1025. [DOI] [Details]
O'Sullivan A, Gibney MJ, Brennan L. (2011) 'Dietary intake patterns are reflected in metabolomic profiles: potential role in dietary assessment studies'. American Journal of Clinical Nutrition, 93 (2):314-321. [DOI] [Details]
O'Sullivan A, Gibney MJ, O'Connor A, Mion B, Kaluskar S, Cashman KD, Flynn A, Shanahan F, Brennan L. (2011) 'Biochemical and metabolomic phenotyping in the identification of a vitamin D responsive metabotype for markers of the metabolic syndrome'. Molecular Nutrition and Food Research, 55 (5):679-690. [DOI] [Details]
O'Sullivan A, Willoughby RE, Mishchuk D, Alcarraz B, Cabezas-Sanchez C, Condori RE, David D, Encarnacion R, Fatteh N, Fernandez J, Franka R, Hedderwick S, McCaughey C, Ondrush J, Paez-Martinez A, Rupprecht C, Velasco-Villa A, Slupsky CM (2012) 'Metabolomics of cerebrospinal fluid from humans treated for rabies'. Journal of Proteome Research, 12 (1):481-90. [DOI] [Details]
Zivkovic A, Yang J, Georgi K, Hegedus C, Nording M, O'Sullivan A, German JB, Hogg R, Weiss R, Bay C, Hammock, B. (2012) 'Serum oxylipin profiles in IgA nephropathy patients reflect kidney functional alterations'. Metabolomics, 8 (6):1102-1113. [DOI] [Details]
 

Conference Publications

O'Connor A, Brennan L, Mion B, O'Sullivan A, Kaluskar S, Cashman KD, Flynn A, Marchesi J, Shanahan F, Gibney MJ. (2010) Effects of probiotic supplementation on gut microbiota composition and immunological markers in healthy volunteers Nutrition Society Summer Meeting [DOI] [Details]
O'Sullivan A, Brennan L, Mion B, O'Connor A, Kaluskar S, Cashman KD, Flynn A, Marchesi J, Shanahan F, Gibney MJ (2010) Investigating physiological variation in healthy Irish adults using a combination of traditional techniques and emerging metabolomic technologies Nutrition Society Summer Meeting [DOI] [Details]
                                                                                                                                       

Research

Research Interests

My principal research interests lie in the application of metabolomics in nutritional sciences. I have made significant progress in two areas of research.

The first involves using metabolomics along with other analytical and statistical tools to examine variation in response to dietary interventions and identify metabolic phenotypes associated with specific responses. The direct impact of this research would see the development of personalised diet and lifestyle recommendations to improve health status across the population.

The second area of research focuses on infant nutrition. I am currently interested in applying metabolomic techniques and other strategies to better understand the metabolic implications of a variety of factors for healthy infant development during the first 1000 days of life; from maternal health status to early infant exposures, such as feeding practices.

Research Projects

Sponsor : University College Dublin (UCD)
Title : Metabolomic profiling to investigate the role of nutrition as a determinant of treatment outcome for HIV infected adults and children in Uganda.
Start Date / End Date : 01-APR-14 / 30-MAR-16
Sponsor : University College Dublin (UCD)
Title : Aifric O'Sullivan Start up Grant
Start Date / End Date : 01-JUL-14 / 31-DEC-15
Sponsor : University College Dublin (UCD)
Title : Metabolic implications of early infant feeding practices in Ireland.
Start Date / End Date : 01-MAY-13 / 31-OCT-14
   

Teaching

Teaching Philosophy

While understanding knowledge is fundamental to learning, critical thinking and curiosity are essential to progress from a point of accumulating information to a point where the student can conceptualize, apply, analyze, synthesize, and evaluate information. Learning is a two-way process where the teacher and students can inform, educate and inspire.
         

Collaborators

Internal Collaborators

Prof. Mike Gibney, UCD

Dr. Lorraine Brennan, UCD

Dr. Jim Kinsella, UCD

Dr. Deirdre O'Connor, UCD

External Collaborators

Prof. Nora O'Brien, UCC

Dr. Nick Chisholm, UCC

Dr. Edward Lahiff, UCC

Dr. Kathy Glavanis-Grantham, UCC

Dr Fiona Lithander
Australian National University and Trinity College Dublin

Prof. Bruce German
Director, Foods For Health Institute
Department of Food Science & Technology
University of California, Davis, CA 95616

Asst. Prof. Carolyn Slupsky
Department of Food Science & Technology
University of California, Davis, CA 95616

Dr. John Newman
USDA, ARS Western Human Nutrition Research Center
430 West Health Sciences Drive
University of California, Davis, CA 95616

Dr. Charles Stephensen
USDA, ARS Western Human Nutrition Research Center
430 West Health Sciences Drive
University of California, Davis, CA 95616