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Researchers at UCD

researcher

Patrick Lonergan

Professor

School Of Agriculture & Food Science
Agriculture and Food Science
Belfield
Dublin 4

Tel: +353 1 7167781
Email: pat.lonergan@ucd.ie

Professional

               

Education

Year 1990 Institution: University College Dublin
Qualification: MAgrSc Subject:
Year 1992 Institution: University College Dublin
Qualification: PhD Subject:
Year 1989 Institution: University College Dublin
Qualification: BAgrSc Subject:
         

Publications

 

Book Chapters

Lonergan, P.; (2007) 'State-of-the-art embryo technologies in ruminants' In: Lonergan, P.; (eds). Reproduction in Domestic Animals. London: Society for Reproduction and Fertility. [Details]
 

Peer Reviewed Journals

Cummins, SB,Waters, SM,Evans, ACO,Lonergan, P,Butler, ST (2012) 'Genetic merit for fertility traits in Holstein cows: III. Hepatic expression of somatotropic axis genes during pregnancy and lactation'. Journal of Dairy Science, 95 :3711-3721. [DOI] [Details]
Leal, CLV,Mamo, S,Fair, T,Lonergan, P (2012) 'Gene Expression in Bovine Oocytes and Cumulus Cells After Meiotic Inhibition with the Cyclin-Dependent Kinase Inhibitor Butyrolactone I'. Reproduction in Domestic Animals, 47 :615-624. [DOI] [Details]
Mamo, S,Mehta, JP,Forde, N,McGettigan, P,Lonergan, P (2012) 'Conceptus-Endometrium Crosstalk During Maternal Recognition of Pregnancy in Cattle'. Biology of Reproduction, 87 . [DOI] [Details]
Fair, T,Lonergan, P (2012) 'The Role of Progesterone in Oocyte Acquisition of Developmental Competence'. Reproduction in Domestic Animals, 47 :142-147. [DOI] [Details]
Hutchinson, IA,Dewhurst, RJ,Evans, ACO,Lonergan, P,Butler, ST (2012) 'Effect of grass dry matter intake and fat supplementation on progesterone metabolism in lactating dairy cows'. Theriogenology, 78 :878-886. [DOI] [Details]
Forde, N,Carter, F,di Francesco, S,Mehta, JP,Garcia-Herreros, M,Gad, A,Tesfaye, D,Hoelker, M,Schellander, K,Lonergan, P (2012) 'Endometrial response of beef heifers on day 7 following insemination to supraphysiological concentrations of progesterone associated with superovulation'. Physiological Genomics, 44 :1107-1115. [DOI] [Details]
Eozenou, C,Carvalho, AV,Forde, N,Giraud-Delville, C,Gall, L,Lonergan, P,Auguste, A,Charpigny, G,Richard, C,Pannetier, M,Sandra, O (2012) 'FOXL2 Is Regulated During the Bovine Estrous Cycle and Its Expression in the Endometrium Is Independent of Conceptus-Derived Interferon Tau'. Biology of Reproduction, 87 . [DOI] [Details]
Forde, N,Mehta, JP,Minten, M,Crowe, MA,Roche, JF,Spencer, TE,Lonergan, P (2012) 'Effects of Low Progesterone on the Endometrial Transcriptome in Cattle'. Biology of Reproduction, 87 (5):124, 1-11. [DOI] [Details]
Mansouri-Attia, N,Oliveira, LJ,Forde, N,Fahey, AG,Browne, JA,Roche, JF,Sandra, O,Reinaud, P,Lonergan, P,Fair, T (2012) 'Pivotal Role for Monocytes/Macrophages and Dendritic Cells in Maternal Immune Response to the Developing Embryo in Cattle'. Biology of Reproduction, 87 . [DOI] [Details]
Lonergan P (2012) 'The two-cell embryo--two sides of the same coin?'. Biology of Reproduction, 87 (6). [DOI] [Details]
Rizos, D,Scully, S,Kelly, AK,Ealy, AD,Moros, R,Duffy, P,Al Naib, A,Forde, N,Lonergan, P (2012) 'Effects of human chorionic gonadotrophin administration on Day 5 after oestrus on corpus luteum characteristics, circulating progesterone and conceptus elongation in cattle'. Reproduction, Fertility and Development, 24 :472-481. [DOI] [Details]
Hutchinson, IA,Hennessy, AA,Dewhurst, RJ,Evans, ACO,Lonergan, P,Butler, ST (2012) 'The effect of strategic supplementation with trans-10,cis-12 conjugated linoleic acid on the milk production, estrous cycle characteristics, and reproductive performance of lactating dairy cattle'. Journal of Dairy Science, 95 :2442-2451. [DOI] [Details]
Mossa, F,Walsh, SW,Butler, ST,Berry, DP,Carter, F,Lonergan, P,Smith, GW,Ireland, JJ,Evans, ACO (2012) 'Low numbers of ovarian follicles >= 3 mm in diameter are associated with low fertility in dairy cows'. Journal of Dairy Science, 95 :2355-2361. [DOI] [Details]
Parr, MH,Mullen, MP,Crowe, MA,Roche, JF,Lonergan, P,Evans, ACO,Diskin, MG (2012) 'Relationship between pregnancy per artificial insemination and early luteal concentrations of progesterone and establishment of repeatability estimates for these traits in Holstein-Friesian heifers'. Journal of Dairy Science, 95 :2390-2396. [DOI] [Details]
O'Hara, L,Scully, S,Maillo, V,Kelly, AK,Duffy, P,Carter, F,Forde, N,Rizos, D,Lonergan, P (2012) 'Effect of follicular aspiration just before ovulation on corpus luteum characteristics, circulating progesterone concentrations and uterine receptivity in single-ovulating and superstimulated heifers'. Reproduction, 143 :673-682. [DOI] [Details]
Richardson, L,Hanrahan, JP,Donovan, A,Marti, JI,Fair, S,Evans, ACO,Lonergan, P (2012) 'Effect of site of deposition on the fertility of sheep inseminated with frozen-thawed semen'. Animal Reproduction Science, 131 :160-164. [DOI] [Details]
Hutchinson, IA,Hennessy, AA,Waters, SM,Dewhurst, RJ,Evans, ACO,Lonergan, P,Butler, ST (2012) 'Effect of supplementation with different fat sources on the mechanisms involved in reproductive performance in lactating dairy cattle'. Theriogenology, 78 :12-27. [DOI] [Details]
Maillo, V,Rizos, D,Besenfelder, U,Havlicek, V,Kelly, AK,Garrett, M,Lonergan, P (2012) 'Influence of lactation on metabolic characteristics and embryo development in postpartum Holstein dairy cows'. Journal of Dairy Science, 95 :3865-3876. [DOI] [Details]
Cummins, SB,Lonergan, P,Evans, ACO,Butler, ST (2012) 'Genetic merit for fertility traits in Holstein cows: II. Ovarian follicular and corpus luteum dynamics, reproductive hormones, and estrus behavior'. Journal of Dairy Science, 95 :3698-3710. [DOI] [Details]
Gath, VP, Crowe, MA, O'Callaghan, D, Boland, MP, Duffy, P, Lonergan, P, Mulligan, FJ (2012) 'Effects of diet type on establishment of pregnancy and embryo development in beef heifers'. Animal Reproduction Science, 133 (3):139-145. [Details]
Sikora, K. M., Magee, D. A., Berkowicz, E. W., Lonergan, P., Evans, A. C. O., Carter, F., Comte, A., Waters, S. M., MacHugh, D. E., Spillane, C. (2012) 'PHLDA2 is an imprinted gene in cattle'. Animal Genetics, 43 (5):587-590. Available Online [Details]
Beltman ME, Forde N, Lonergan P, Crowe MA. (2012) 'Altered endometrial immune gene expression in beef heifers with retarded embryos'. Reproduction Fertility and Development, . [DOI] Link to full text [Details]
Garcia-Herreros, M,Aparicio, IM,Rath, D,Fair, T,Lonergan, P (2012) 'Differential glycolytic and glycogenogenic transduction pathways in male and female bovine embryos produced in vitro'. Reproduction, Fertility and Development, 24 :344-352. [DOI] [Details]
Matoba, S,O'Hara, L,Carter, F,Kelly, AK,Fair, T,Rizos, D,Lonergan, P (2012) 'The association between metabolic parameters and oocyte quality early and late postpartum in Holstein dairy cows'. Journal of Dairy Science, 95 :1257-1266. [DOI] [Details]
Cummins, SB,Lonergan, P,Evans, ACO,Berry, DP,Evans, RD,Butler, ST (2012) 'Genetic merit for fertility traits in Holstein cows: I. Production characteristics and reproductive efficiency in a pasture-based system'. Journal of Dairy Science, 95 :1310-1322. [DOI] [Details]
Matoba S, Bender K, Fahey AG, Mamo S, Brennan L, Lonergan P, Fair T (2013) 'Predictive value of bovine follicular components as markers of oocyte developmental potential'. Reproduction, Fertility and Development, . [DOI] [Details]
Maillo V, Duffy P, O'Hara L, de Frutos C, Kelly AK, Lonergan P, Rizos D (2013) 'Effect of hCG administration during corpus luteum establishment on subsequent corpus luteum development and circulating progesterone concentrations in beef heifers'. Reproduction, Fertility and Development, . [DOI] [Details]
Scully S, Maillo V, Duffy P, Kelly A, Crowe M, Rizos D, Lonergan P (2013) 'The Effect of Lactation on Post-Partum Uterine Involution in Holstein Dairy Cows'. Reproduction in domestic animals = Zuchthygiene, 48 :888-892. [DOI] [Details]
Forde N, Mehta JP, McGettigan PA, Mamo S, Bazer FW, Spencer TE, Lonergan P (2013) 'Alterations in expression of endometrial genes coding for proteins secreted into the uterine lumen during conceptus elongation in cattle'. Genomics, 14 . [DOI] [Details]
Spencer TE, Forde N, Dorniak P, Hansen TR, Romero JJ, Lonergan P (2013) 'Conceptus-derived prostaglandins regulate gene expression in the endometrium prior to pregnancy recognition in ruminants'. Reproduction, 146 (4):377-387. [DOI] [Details]
Mossa, F,Carter, F,Walsh, SW,Kenny, DA,Smith, GW,Ireland, JLH,Hildebrandt, TB,Lonergan, P,Ireland, JJ,Evans, ACO (2013) 'Maternal Undernutrition in Cows Impairs Ovarian and Cardiovascular Systems in Their Offspring'. Biology of Reproduction, 88 . [DOI] [Details]
Forde N, Mehta JP, Minten M, Crowe MA, Roche JF, Spencer TE, Lonergan P (2012) 'Effects of Low Progesterone on the Endometrial Transcriptome in Cattle'. Biology of Reproduction, . [DOI] [Details]
Forde N, Carter F, di Francesco S, Prakash Mehta J, Garcia-Herreros M, Gad AY, Tesfaye D, Hoelker M, Schellander K, Lonergan P (2012) 'Endometrial response of beef heifers on Day 7 following insemination to supra-physiological concentrations of progesterone associated with superovulation'. Genomics, . [DOI] [Details]
Beltman ME, Forde N, Lonergan P, Crowe MA (2012) 'Altered endometrial immune gene expression in beef heifers with retarded embryos'. Reproduction, Fertility and Development, . [DOI] [Details]
Mamo S, Rizos D, Lonergan P (2012) 'Transcriptomic changes in the bovine conceptus between the blastocyst stage and initiation of implantation'. Animal Reproduction Science, 134 (1-2):56-63. [DOI] [Details]
Hutchinson IA, Dewhurst RJ, Evans AC, Lonergan P, Butler ST (2012) 'Effect of grass dry matter intake and fat supplementation on progesterone metabolism in lactating dairy cows'. Theriogenology, 78 (4):878-886. [DOI] [Details]
Gath VP, Crowe MA, O'Callaghan D, Boland MP, Duffy P, Lonergan P, Mulligan FJ (2012) 'Effects of diet type on establishment of pregnancy and embryo development in beef heifers'. Animal Reproduction Science, 133 (3-4):139-145. [DOI] [Details]
Cummins SB, Lonergan P, Evans AC, Butler ST (2012) 'Genetic merit for fertility traits in Holstein cows: II. Ovarian follicular and corpus luteum dynamics, reproductive hormones, and estrus behavior'. Journal of Dairy Science, 95 (7):3698-3710. [DOI] [Details]
Maillo V, Rizos D, Besenfelder U, Havlicek V, Kelly AK, Garrett M, Lonergan P (2012) 'Influence of lactation on metabolic characteristics and embryo development in postpartum Holstein dairy cows'. Journal of Dairy Science, 95 (7):3865-3876. [DOI] [Details]
Matoba S, O'Hara L, Carter F, Kelly AK, Fair T, Rizos D, Lonergan P (2012) 'The association between metabolic parameters and oocyte quality early and late postpartum in Holstein dairy cows'. Journal of Dairy Science, 95 (3):1257-1266. [DOI] [Details]
Rizos D, Scully S, Kelly AK, Ealy AD, Moros R, Duffy P, Al Naib A, Forde N, Lonergan P (2012) 'Effects of human chorionic gonadotrophin administration on day 5 after oestrus on corpus luteum characteristics, circulating progesterone and conceptus elongation in cattle'. Reproduction, Fertility and Development, 24 (3):472-481. [DOI] [Details]
Hutchinson IA, Hennessy AA, Dewhurst RJ, Evans AC, Lonergan P, Butler ST (2012) 'The effect of strategic supplementation with trans-10,cis-12 conjugated linoleic acid on the milk production, estrous cycle characteristics, and reproductive performance of lactating dairy cattle'. Journal of Dairy Science, 95 (5):2442-2451. [DOI] [Details]
Mossa F, Walsh SW, Butler ST, Berry DP, Carter F, Lonergan P, Smith GW, Ireland JJ, Evans AC (2012) 'Low numbers of ovarian follicles â¿¥3 mm in diameter are associated with low fertility in dairy cows'. Journal of Dairy Science, 95 (5):2355-2361. [DOI] [Details]
Parr MH, Mullen MP, Crowe MA, Roche JF, Lonergan P, Evans AC, Diskin MG (2012) 'Relationship between pregnancy per artificial insemination and early luteal concentrations of progesterone and establishment of repeatability estimates for these traits in Holstein-Friesian heifers'. Journal of Dairy Science, 95 (5):2390-2396. [DOI] [Details]
Richardson L, Hanrahan JP, Donovan A, Martí JI, Fair S, Evans AC, Lonergan P (2012) 'Effect of site of deposition on the fertility of sheep inseminated with frozen-thawed semen'. Animal Reproduction Science, 131 (3-4):160-164. [DOI] [Details]
O'Hara L, Scully S, Maillo V, Kelly AK, Duffy P, Carter F, Forde N, Rizos D, Lonergan P (2012) 'Effect of follicular aspiration just before ovulation on corpus luteum characteristics, circulating progesterone concentrations and uterine receptivity in single-ovulating and superstimulated heifers'. Reproduction, 143 (5):673-682. [DOI] [Details]
Hutchinson IA, Hennessy AA, Waters SM, Dewhurst RJ, Evans AC, Lonergan P, Butler ST (2012) 'Effect of supplementation with different fat sources on the mechanisms involved in reproductive performance in lactating dairy cattle'. Theriogenology, 78 (1):12-27. [DOI] [Details]
Garcia-Herreros M, Aparicio IM, Rath D, Fair T, Lonergan P (2012) 'Differential glycolytic and glycogenogenic transduction pathways in male and female bovine embryos produced in vitro'. Reproduction, Fertility and Development, 24 (2):344-352. [DOI] [Details]
Cummins SB, Lonergan P, Evans AC, Berry DP, Evans RD, Butler ST (2012) 'Genetic merit for fertility traits in Holstein cows: I. Production characteristics and reproductive efficiency in a pasture-based system'. Journal of Dairy Science, 95 (3):1310-1322. [DOI] [Details]
Cummins SB, Waters SM, Evans AC, Lonergan P, Butler ST (2012) 'Genetic merit for fertility traits in Holstein cows: III. Hepatic expression of somatotropic axis genes during pregnancy and lactation'. Journal of Dairy Science, 95 (7):3711-3721. [DOI] [Details]
Forde N, Lonergan P (2012) 'Transcriptomic analysis of the bovine endometrium: What is required to establish uterine receptivity to implantation in cattle?'. Journal of Reproduction and Development, 58 (2):189-195. [Details]
Fair T, Lonergan P (2012) 'The role of progesterone in oocyte acquisition of developmental competence'. Reproduction in Domestic Animals, 47 Suppl 4 :142-147. [DOI] [Details]
Sikora KM, Magee DA, Berkowicz EW, Lonergan P, Evans AC, Carter F, Comte A, Waters SM, Machugh DE, Spillane C (2012) 'PHLDA2 is an imprinted gene in cattle'. Animal Genetics, 43 (5):587-590. [DOI] [Details]
Mamo S, Mehta JP, Forde N, McGettigan P, Lonergan P (2012) 'Conceptus-endometrium crosstalk during maternal recognition of pregnancy in cattle'. Biology of Reproduction, 87 (1):1-9. [DOI] [Details]
Eozenou C, Carvalho AV, Forde N, Giraud-Delville C, Gall L, Lonergan P, Auguste A, Charpigny G, Richard C, Pannetier M, Sandra O (2012) 'FOXL2 is regulated during the bovine estrous cycle and its expression in the endometrium is independent of conceptus-derived interferon tau'. Biology of Reproduction, 87 (2). [DOI] [Details]
Forde N, Duffy GB, McGettigan PA, Browne JA, Mehta JP, Kelly AK, Mansouri-Attia N, Sandra O, Loftus BJ, Crowe MA, Fair T, Roche JF, Lonergan P, Evans AC (2012) 'Evidence for an early endometrial response to pregnancy in cattle: both dependent upon and independent of interferon tau'. Genomics, 44 (16):799-810. [DOI] [Details]
Bermejo-Alvarez P, Rizos D, Lonergan P, Gutierrez-Adan A; (2011) 'Transcriptional sexual dimorphism during preimplantation embryo development and its consequences for developmental competence and adult health and disease'. Reproduction, 141 (5):563-570. [DOI] [Details]
Ireland JJ, Smith GW, Scheetz D, Jimenez-Krassel F, Folger JK, Ireland JL, Mossa F, Lonergan P, Evans AC (2011) 'Does size matter in females? An overview of the impact of the high variation in the ovarian reserve on ovarian function and fertility, utility of anti-Müllerian hormone as a diagnostic marker for fertility and causes of variation in the ovarian reserve in cattle'. Reproduction, Fertility and Development, 23 (1):1-14. [DOI] [Details]
Gad A, Besenfelder U, Rings F, Ghanem N, Salilew-Wondim D, Hossain MM, Tesfaye D, Lonergan P, Becker A, Cinar U, Schellander K, Havlicek V, Hölker M (2011) 'Effect of reproductive tract environment following controlled ovarian hyperstimulation treatment on embryo development and global transcriptome profile of blastocysts: implications for animal breeding and human assisted reproduction'. Human reproduction (Oxford, England), 26 (7):1693-1707. [DOI] [Details]
Richardson L, Hanrahan JP, O'Hara L, Donovan A, Fair S, O'Sullivan M, Carrington SD, Lonergan P, Evans AC; (2011) 'Ewe breed differences in fertility after cervical AI with frozen-thawed semen and associated differences in sperm penetration and physicochemical properties of cervical mucus'. Animal Reproduction Science, 129 (1-2):37-43. [DOI] [Details]
Forde N, Carter F, Spencer TE, Bazer FW, Sandra O, Mansouri-Attia N, Okumu LA, McGettigan PA, Mehta JP, McBride R, O'Gaora P, Roche JF, Lonergan P; (2011) 'Conceptus-induced changes in the endometrial transcriptome: how soon does the cow know she is pregnant?'. Biology of Reproduction, 85 (1):144-156. [DOI] [Details]
Hutchinson I, de Veth MJ, Stanton C, Dewhurst RJ, Lonergan P, Evans AC, Butler ST; (2011) 'Effects of lipid-encapsulated conjugated linoleic acid supplementation on milk production, bioenergetic status and indicators of reproductive performance in lactating dairy cows'. Journal of Dairy Research, 78 (3):308-317. [DOI] [Details]
Leal C, Mamo S, Fair T, Lonergan P; (2011) 'Gene Expression in Bovine Oocytes and Cumulus Cells After Meiotic Inhibition with the Cyclin-Dependent Kinase Inhibitor Butyrolactone I'. Reproduction in Domestic Animals, . [DOI] [Details]
Pluta, K., Irwin, J.A., Dolphin, C., Richardson, L., Fitzpatrick, E., Gallagher, M.E., Reid, C.J, Crowe, M.A., Roche, J.F., Lonergan, P., Carrington, S.D., Evans, A,C, (2011) 'Glycoproteins and glycosidases of the cervix during the periestrous period in cattle'. Animal Science, 89 (12):4032-4042. [DOI] [Details]
Al Naib A, Hanrahan JP, Lonergan P, Fair S; (2011) 'In vitro assessment of sperm from bulls of high and low field fertility'. Theriogenology, 76 (1):161-167. [DOI] [Details]
Al Naib A, Ward F, Kelly AK, Wade M, Marti JI, Lonergan P; (2011) 'Effect of duration of storage at ambient temperature on fertilizing ability and mucus penetration ability of fresh bovine sperm'. Theriogenology, 76 (6):1070-1075. [DOI] [Details]
Arias-Alvarez M, Bermejo-Alvarez P, Gutierrez-Adan A, Rizos D, Lorenzo PL, Lonergan P; (2011) 'Effect of leptin supplementation during in vitro oocyte maturation and embryo culture on bovine embryo development and gene expression patterns'. Theriogenology, 75 (5):887-896. [DOI] [Details]
Lonergan P; (2011) 'Autocrine embryotropins in embryo development: controlling one's own fate'. Biology of Reproduction, 84 (6):1075-1076. [DOI] [Details]
Aparicio IM, Garcia-Herreros M, O'Shea LC, Hensey C, Lonergan P, Fair T.; (2011) 'Expression, regulation, and function of progesterone receptors in bovine cumulus oocyte complexes during in vitro maturation'. Biology of reproduction, 84 (5):910-921. [Details]
Mamo S, Carter F, Lonergan P, Leal CL, Al Naib A, McGettigan P, Mehta JP, Evans AC, Fair T.; (2011) 'Sequential analysis of global gene expression profiles in immature and in vitro matured bovine oocytes: potential molecular markers of oocyte maturation'. BMC Genomics, 16 (12). [Details]
Okumu L.A., Fair T., Szekeres-Bartho J., O'Doherty A.M., Crowe M.A., Roche J.F., Lonergan P. and Forde N. (2011) 'Endometrial expression of progesterone induced blocking factor and galectins-1, -3, -9 and -3 binding protein in the luteal phase and early pregnancy in cattle'. Physiological genomics, 43 :903-910. [Details]
Mamo S, Mehta JP, McGettigan P, Fair T, Spencer TE, Bazer FW, Lonergan P.; (2011) 'RNA Sequencing Reveals Novel Gene Clusters in Bovine Conceptuses Associated with Maternal Recognition of Pregnancy and Implantation'. Biology of Reproduction, . [Details]
Al Naib A, Mamo S, O'Gorman GM, Lonergan P, Swales A, Fair T.; (2011) 'Regulation of non-classical major histocompatability complex class I mRNA expression in bovine embryos'. JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 91 (1-2):31-40. [Details]
Bermejo-Alvarez P, Rizos D, Lonergan P, Gutierrez-Adan A; (2011) 'Transcriptional sexual dimorphism in elongating bovine embryos: implications for XCI and sex determination genes'. Reproduction, 141 (6):801-808. [DOI] [Details]
Lonergan P; (2011) 'Influence of progesterone on oocyte quality and embryo development in cows'. Theriogenology, 76 (9):1594-1601. [DOI] [Details]
O'Meara CM, Murray JD, Mamo S, Gallagher E, Roche J, Lonergan P; (2011) 'Gene silencing in bovine zygotes: siRNA transfection versus microinjection'. Reproduction, Fertility and Development, 23 (4):534-543. [DOI] [Details]
Bermejo-Alvarez, P.,Rizos, D.,Rath, D.,Lonergan, P.,Gutierrez-Adan, A.; (2010) 'Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts'. Proceedings of the National Academy of Sciences of the United States of America, 107 (8):3394-3399. [DOI] [Details]
Crowe MA, Beltman ME, Lonergan P, Diskin MG, Roche JF, ; (2009) 'Effect of progesterone supplementation in the first week post conception on embryo survival in beef heifers'. Theriogenology, 71 (7):1173-1179. [DOI] [Details]
Evans AC, McAuliffe FM, Quinn K, Lonergan P, Smith NA, ; (2009) 'Transient high glycaemic intake in the last trimester of pregnancy increases offspring birthweight and postnatal growth rate in sheep: a randomised control trial'. Bjog-An International Journal of Obstetrics and Gynaecology, 116 (7):975-983. [DOI] [Details]
Lonergan P, Carter F, Forde N, Duffy P, Wade M, Fair T, Crowe MA, Evans AC, Kenny DA, Roche JF, ; (2008) 'Effect of increasing progesterone concentration from Day 3 of pregnancy on subsequent embryo survival and development in beef heifers'. Reproduction, fertility, and development, 3 (NA):368-375. [Details]
Bermejo-Alvarez, P., Rizos, D., Rath, D., Lonergan, P., Gutierrez-Adan, A., ; (2008) 'Epigenetic differences between male and female bovine blastocysts produced in vitro'. Physiological Genomics, 32 (2):264-272. [Details]
Clemente, M., Lonergan, P., Borque, C., de la Fuente, J., Rizos, D., ; (2008) 'Effect of exogenous progesterone during in vitro culture on early embryo development in cattle'. Reproduction, Fertility and Development, 20 (1):179-179. [Details]
Berry, D. P., Lonergan, P., Butler, S. T., Cromie, A. R., Fair, T., Mossa, F., Evans, A. C. O., ; (2008) 'Negative influence of high maternal milk production before and after conception on offspring survival and milk production in dairy cattle'. Journal of Dairy Science, 91 (1):329-337. [Details]
Rizos, D., Bermejo-Alvarez, P., Gutierrez-Adan, A., Lonergan, P., ; (2008) 'Effect of duration of oocyte maturation on the kinetics of cleavage, embryo yield and sex ratio in cattle'. Reproduction, Fertility and Development, 20 (6):734-740. [Details]
Forde, N., Rogers, M., Canty, M. J., Lonergan, P., Smith, G. W., Coussens, P. M., Ireland, J. J., Evans, A. C. O., ; (2008) 'Association of the prion protein and its expression with ovarian follicle development in cattle'. Molecular Reproduction and Development, 75 (2):243-249. [Details]
Bermejo-Alvarez, P., Gutierrez-Adan, A., Lonergan, P., Rizos, D., ; (2008) 'Does duration of bovine oocyte maturation in vitro affect the speed of embryo development in vitro and sex ratio at the two-cell or blastocyst stage?'. Reproduction, Fertility and Development, 20 (1):177-178. [Details]
Sweeney, T., Fox, J., Robertson, L., Kelly, G., Duffy, P., Lonergan, P., O'Doherty, J., Roche, J.F., Evans, N.P. ; (2007) 'Postnatal exposure to octylphenol decreases semen quality in the adult ram'. Theriogenelogy, 67 (5):1068-1075. [Details]
Lonergan, P., Woods, A., Fair, T., Carter, F., Rizos, D., Ward, F., Quinn, K., Evans, A.C.O. ; (2007) 'Effect of embryo source and recipient progesterone environment on embryo development in cattle'. Reproduction, Fertility and Development, 19 (7):861-868. [Details]
Tesfaye, D., Nganvongpanit, K., Besenfelder, U., Lonergan, P., Schellander, K. ; (2007) 'Suppression of connexin 43 and E-cadherin transcripts in in vitro derived bovine embryos following culture in vitro or in vivo in the homologous bovine oviduct'. Molecular Reproduction and Development, 74 (8):978-988. [Details]
Lonergan, P., Evans, A.C.O., Boland, E., Rizos, D., Fair, T., Duffy, P., Sung, L.Y., Du, F., Chaubal, S., Xu, J., Yang, X., Tian, X.C.; (2007) 'Pregnancy and fetal characteristics after transfer of vitrified in vivo and cloned bovine embryos'. Theriogenelogy, 68 (8):1128-1137. [Details]
O'Meara, C., Hanrahan, J.P., Donovan, A., Duffy, P., Evans, A.C.O., Lonergan, P. ; (2007) 'Resuspending ram spermatozoa in seminal plasma after cryopreservation does not improve pregnancy rate in cervically inseminated ewes'. Theriogenelogy, 67 (7):1262-1268. [Details]
Fair, T., Carter, F., Park, S., Evans, A.C.O., Lonergan, P. ; (2007) 'Global gene expression analysis during bovine oocyte in vitro maturation'. Theriogenelogy, 68 (Supplement 1):91-97. [Details]
Watson, A., Duranthon, V., Lonergan, P.; (2007) 'Preimplantation embryo programming: transcription, epigenetics and culture environment'. Reproduction, . [Details]
Ireland, J.J., Ward, F., Jimenez-Krassel, F., Ireland, J.L.H., Smith, G.W., Lonergan, P., E.vans, A.C.O.; (2007) 'Follicle numbers are highly repeatable within animal but inversely correlated with FSH concentrations and the proportion of good quality embryos after superstimulation in cattle'. Human Reproduction, 22 (6):1687-1695. [Details]
Rizos, D., Pintado, B., de la Fuente, J., Lonergan, P., Gutierrez-Adan, A. ; (2007) 'Development and pattern of mRNA relative abundance of bovine embryos cultured in the isolated mouse oviduct in organ culture'. Molecular Reproduction and Development, 74 (6):716-723. [Details]
Fair, T, Carter, F, Park, S, Evans, ACO, Lonergan, P, ; (2007) 'Global gene expression analysis during bovine oocyte in vitro maturation'. Theriogenology, 68 :91-97. [Details]
Ireland, J, Smith, G, Evans, A, Lonergan, P, Jimenez-Krassel, F, Scheetz, D, Folger, J, ; (2007) 'Does variation in size of the ovarian reserve and fsh secretion impact fertility?'. Biology of Reproduction, :69-70. [Details]
Ireland, J, Jimenez-Krassel, F, Smith, G, Lonergan, P, Evans, A, ; (2007) 'Variation in number of follicles growing during follicular waves reflects size of the ovarian reserve in cattle'. Biology of Reproduction, :128-129. [Details]
Corcoran, D, Rizos, D, Fair, T, Evans, ACO, Lonergan, P, ; (2007) 'Temporal expression of transcripts related to embryo quality in bovine embryos cultured from the two-cell to blastocyst stage in vitro or in vivo'. Molecular Reproduction and Development, 74 :972-977. [Details]
Garcia-Garcia, RM, Ward, E, Fair, S, OMeara, CM, Wade, M, Duffy, P, Lonergan, P, ; (2007) 'Development and quality of sheep embryos cultured in commercial G1.3/G2.3 sequential media'. Animal Reproduction Science, 98 :233-240. [Details]
Jimenez-Krassel, F, Smith, G, Lonergan, P, Evans, A, Ireland, J, ; (2007) 'Evidence that luteinization capacity of granulosal cells from dominant follicles is diminished in cattle with a depleted ovarian reserve'. Biology of Reproduction, :155-155. [Details]
Rizos, D., Lonergan, P., Rath, D., De la Fuente, J., Wade, M., Parrilla-Riera, I., Gutierrez-Adan, A. ; (2007) 'Differences in transcript abundance between male and female bovine blastocysts produced in vitro using sexed semen'. REPRODUCTION FERTILITY AND DEVELOPMENT, 19 (1):255-255. [Details]
Smith, N.A., Lonergan, P., Duffy, P., Crosby, T.F., Quinn, P., McAuliffe, F., Evans, A.C.O.; (2007) 'Undernutrition during the periconceptional period in ewes affects the blood pressure and weight of their neonatal lambs'. REPRODUCTION FERTILITY AND DEVELOPMENT, 19 (1):194-195. [Details]
Doyle, J; Ellis, SA; Lonergan, P; Fair, T; ; (2007) 'Classical and non-classical major histocompatability complex class I gene expression in in vitro-derived bovine embryos'. Reproduction, Fertility and Development, 19 (1):250-250. [Details]
Carter, F; Fair, T; Park, S; Wade, M; Evans, ACO; Lonergan, P; ; (2007) 'Gene expression profiling of immature and in vitro-matured bovine oocytes using affymetrix genechip technology'. Reproduction, Fertility and Development, 19 (1):248-248. [Details]
Mossa F, Duffy P, Naitana S, Lonergan P, Evans ACO ; (2007) 'Association between numbers of ovarian follicles in the first follicle wave and superovulatory response in ewes'. Animal Reproduction Science, 100 (3-4):391-396. [Details]
Corcoran D, Fair T, Rizos D, Patel OV, Smith GW, Ireland JJ, Coussens PM, Boland MP, Evans ACO, Lonergan P; (2006) 'Differential developmental competence of in vivo compared to in vitro cultured bovine embryos is associated with differential gene expression and a suppression of transcription'. REPRODUCTION, . [Details]
Rosa, M; Coussens, PM; Halgren, R; Evans, ACO; Milim, M; Lonergan, P; Ireland, JJ; ; (2006) 'Interpretation of microarray data: Trudging out of the abyss towards elucidation of biological significance'. Journal of Animal Science, 84 (NA):3-3. [Details]
Ireland, J; Smith, G; Burns, D; Jimenez-Krassel, F; Ireland, J; Knight, P; Ward, F; Lonergan, P; Evans, A; ; (2006) 'The physiological significance of the variation in numbers of follicles during follicular waves in cattle'. Journal of Animal Science, 84 (NA):95-96. [Details]
Gutierrez-Adan, A; Perez-Crespo, M; Fernandez-Gonzalez, R; Ramirez, MA; Moreira, P; Pintado, B; Lonergan, P; Rizos, D; ; (2006) 'Developmental consequences of sexual dimorphism during pre-implantation embryonic development'. Reproduction in Domestic Animals, 41 (NA):54-62. [Details]
Ireland, JJ; Jimenez-Krassel, F; Smith, GW; Ward, F; Lonergan, P; Evans, ACO; ; (2006) 'Evidence that serum progesterone concentrations are different for cattle with high versus low numbers of follicles growing during follicular waves'. Biology of Reproduction, -1 (NA):119-119. [Details]
Corcoran, D., Fair, T, Lonergan, P.; (2006) 'Predicting embryo quality: mRNA expression and the preimplantation embryo'. Reproductive Biomedicine Online, :340-348. [Details]
Corcoran, D., Fair, T., Park, S., Rizos, D., Patel, O.V., Smith, G.W., Coussens, P.M., Ireland, J.J., Boland, M.P., Evans, A.C.O. & Lonergan, P.; (2006) 'Suppressed expression of genes involved in transcription and translation in in vitro compared to in vivo cultured bovine embryos. Reproduction, 131, 651-660'. REPRODUCTION, 131 (3):651-660. [Details]
Perez-Crespo, M., Ramirez, M.A., Fern&ez-Gonzalez, R., Rizos, D., Lonergan, P., Pintado, B., Gutierrez-Adan, A.; (2006) 'Differential sensitivity of male and female mouse embryos to oxidative induced heat-stress is mediated by glucose-6-phosphate dehydrogenase gene expression'. MOLECULAR REPRODUCTION AND DEVELOPMENT, 72 (4):502-510. [Details]
Humblot, P; Holm, P; Lonergan, P; Wrenzycki, C; Lequarre, AS; Joly, CG; Herrmann, D; Lopes, A; Rizos, D; Niemann, H; Callesen, H; ; (2005) 'Effect of stage of follicular growth during superovulation on developmental competence of bovine oocytes'. Theriogenology, 63 (4):1149-1166. [Details]
Forde, N; Canty, MJ; Zielak, AE; Lonergan, P; Smith, GW; Ireland, JJ; Evans, ACO; ; (2005) 'Differential expression of intracellular signalling molecules in dominant compared to subordinate follicles during different stages of the follicle wave in cattle'. Biology of Reproduction, -1 (NA):180-180. [Details]
Ward, F; Lonergan, P; Ireland, JJ; Evans, ACO; ; (2005) 'Number of antral follicles during follicular waves is variable among beef cattle, highly repeatable within individuals, and positivly associated with superovulation response and embryo yield'. Biology of Reproduction, -1 (NA):228-228. [Details]
Patel, OV; Bettegowda, A; Ireland, JJ; Coussens, PM; Lonergan, P; Smith, GW; ; (2005) 'Functional genomics studies of oocyte and early embryonic development: Potential association of follistatin transcript abundance with oocyte competence'. Biology of Reproduction, -1 (NA):145-145. [Details]
Evans, ACO; Ireland, JLH; Winn, ME; Lonergan, P; Smith, GW; Coussens, PM; Ireland, JJ; ; (2004) 'Identification of genes involved in apoptosis and dominant follicle development during follicular waves in cattle'. Biology of Reproduction, 70 (5):1475-1484. [Details]
Gutierrez-Adan, A; Rizos, D; Fair, T; Moreira, PN; Pintado, B; De La Fuente, J; Boland, MP; Lonergan, P; ; (2004) 'Effect of speed of development on mRNA expression pattern in early bovine embryos cultured in vivo or in vitro'. Molecular Reproduction and Development, 68 (4):441-448. [Details]
Lonergan P, Rizos D, Gutierrez-Adan A, Moreira PM, Pintado B, Boland MP; (2003) 'Temporal divergence in the pattern of messenger RNA expression in bovine embryos cultured from the zygote to blastocyst stage in vitro or in vivo'. BIOLOGY OF REPRODUCTION, 69 (4):1424-1431. [Details]
Lonergan, P, Rizos, D, Kanka, J, Nemcova, L, Mbaye, AM, Kingston, M, Wade, M, Duffy, P, Boland, MP, ; (2003) 'Temporal sensitivity of bovine embryos to culture environment after fertilization and the implications for blastocyst quality'. Reproduction, 126 (3):337-346. [DOI] [Details]
Boland MP, Lonergan P, Rizos D, Gutiérrez-Adán A, Fair T, ; (2003) 'Effect of culture environment on embryo quality and gene expression - experience from animal studies'. Reproductive Biomedicine Online, 6 (NA):657-663. [Details]
Gutiérrez-Adán A, Rizos D, Lonergan P, Boland MP, Arroyo-García R, Pintado B, de la Fuente J, ; (2002) 'Analysis of differential messenger RNA expression between bovine blastocysts produced in different culture systems: implications for blastocyst quality'. Biology of Reproduction, 3 (NA):589-595. [Details]
Lonergan, P, Dinnyes, A, Fair, T, Yang, XZ, Boland, M, ; (2000) 'Bovine oocyte and embryo development following meiotic inhibition with butyrolactone I'. Molecular Reproduction and Development, 57 (2):204-209. [Details]
Oussaid, B; Mariana, JC; Poulin, N; Fontaine, J; Lonergan, P; Beckers, JF; Cognie, Y; ; (1999) 'Reduction of the developmental competence of sheep oocytes by inhibition of LH pulses during the follicular phase with a GnRH antagonist'. Journal of Reproduction and Fertility, 117 (1):71-77. [Details]
Dinnyes, A; Lonergan, P; Fair, T; Boland, MP; Yang, XZ; ; (1999) 'Timing of the first cleavage post-insemination affects cryosurvival of in vitro-produced bovine blastocysts'. Molecular Reproduction and Development, 53 (3):318-324. [Details]
Lonergan, P, Piumi, F, Humblot, P, ; (1999) 'Effect of time interval from insemination to first cleavage on the development of bovine embryos in vitro and in vivo'. Theriogenology, 51 (1):326-326. [Details]
Lonergan, P, O'Kearney-Flynn, M, Boland, MP, ; (1999) 'Effect of protein supplementation and presence of an antioxidant on the development of bovine zygotes in synthetic oviduct fluid medium under high or low oxygen tension'. Theriogenology, 51 (8):1565-1576. [Details]
Lonergan, P, Fair, T, Khatir, H, Cesaroni, G, Mermillod, P, ; (1998) 'Effect of protein synthesis inhibition before or during in vitro maturation on subsequent development of bovine oocytes'. Theriogenology, 50 (3):417-431. [Details]
 

Conference Publications

Smith, G.W., Rosa, G.J.M., Coussens, P.M., Halgren, R., Evans, A.C.O., Mihm, M., Lonergan P & Ireland, J.J.; Interpretation of microarray data: Trudging out of the abyss towards elucidation of biological significance Triennial Reproduction Symposium at the American Society of Animal Science,/American Dairy Science Association USA, [Details]
Ward, F., Lonergan, P., Jimenez-Krassel, F., Ireland, J.J., Evans, A.C.O.; (2006) Relationship between peak number of antral follicles during follicular waves, hormone concentrations, superovulatory response and embryo quality in beef heifers Annual Conference of the International Embryo Transfer Society Orlando, Florida, USA, , 08-JAN-06 - 10-JAN-06 [Details]
Ireland, J.J., Smith, G.W., Burns, D., Jimenez-Krassel, J., Ireland, J.L.H., Knight, P.G., Ward, F., Lonergan, P. & Evans, A.C.O.; (2006) The Physiological Significance of the Variation in Numbers of Follicles During Follicular Waves in Cattle Midwestern Section American Dairy Science Association, American Society of Animal Science Annual Meeting , 20-MAR-06 - 22-MAR-06 [Details]
Rizos D, Pintado B, de La Fuente J, Lonergan P, Gutierrez-Adan A; (2006) Bovine embryo development and mRNA expression in blastocysts cultured in isolated mouse oviducts maintained in SOF or KSOM in organ culture Annual Meeting of the International Embryo Transfer Society Orlando, Florida, USA, , 08-JAN-06 - 10-JAN-07 [Details]
Lonergan, P., Fair, T., Corcoran, D., Evans, A.C.O.; (2006) Effect of culture environment on gene expression and developmental characteristics in IVF-derived embryos Post-International Embryo Transfer Society Conference Symposium: 'Realizing the Promise of IVF in Cattle: Optimizing Embryonic and Fetal Survival' Orlando, Florida, USA, , 11-JAN-06 - 11-JAN-06 [Details]
                                                                                         

Research

Research Interests

All aspects of assisted reproduction in animals. Specific interest in embryo production in vitro using in vitro fertilisation technology and in vivo using superovulation and related techniques as tools in the understanding of the control of early mammalian embryonic development. Also an interest in cryopreservation of sperm and embryos.