Navigation

Researchers at UCD

researcher

Alexandre Perochon

Post Doc Research Fellow Lvl I

School Of Biology & Environment Science

Tel: +353 1 716
Email: alexandre.perochon@ucd.ie

Biography

ACADEMIC HISTORY

2011-present
Post-Doctoral Fellow, Microbe-Plant-Interaction-Group,
 UCD School of Biology and Environmental Science, University College Dublin, Ireland

Functional characterisation of toxin- responsive wheat genes

SFI (Science Fundation Ireland) fellowship


2010
PhD in Plant biology, Toulouse University, Calcium Signaling & Plant Stress Responses Group, Lab : CNRS/UPS (National Center for Scientific Research) UMR5546, France

Identification of CML9 interacting proteins, analysis of physical interaction and functional characterization of PRR2, a pseudo response regulator involved in ABA signaling

Advisors: Dr. Ranty Benoit

Publications

     

Peer Reviewed Journals

Perochon, A. Aldon, D. Galaud, J. P. Ranty, B.; (2011) 'Calmodulin and calmodulin-like proteins in plant calcium signaling'. Biochimie, . [Details]
Perochon, A. Dieterle, S. Pouzet, C. Aldon, D. Galaud, J. P. Ranty, B.; (2010) 'Interaction of a plant pseudo-response regulator with a calmodulin-like protein'. Biochemical and Biophysical Research Communications, . [Details]
                                                                                             

Research

Research Interests

  • Plant genetics
  • Biochemical, Molecular and Physiological analysis of environmental stress in plants

Current research

Fusarium fungi that attack wheat can produce a mycotoxin, deoxynivalenol (DON), that acts as a disease virulence factors, facilitating Fusarium parasitism of wheat. DON is a protein synthesis inhibitor, and cause cell death in eukaryotes. The wheat genome has co-evolved with the Fusarium pathogen and its toxic metabolites. We have identified a range of wheat genes that are DON responsive and, in exotic wheat germplasm, most are associated with the phenotypic resistance to both DON-induced bleaching and are located within a chromosomal locus that confers resistance to both DON and Fusarium pathogens. Three of these genes have been shown to directly contribute to the DON resistance of such wheat germplasm (VIGS analysis). One is a novel, evolutionary divergent gene. These and other DON-resistance associated genes, offer potential for enhancing eukaryotic stress tolerance. Using a combination of gene overexpression/silencing studies and a range of analytical and molecular techniques, we now want to determine whether the encoded proteins can enhance biotic and abiotic stress tolerance in whole plants. Additionally, we want to characterise novel genes and associated pathways that enhance plant stress resistance.