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Researchers at UCD

Michael J. Dunn

Pensioners-Salaries

Tel: +353 1 7166927
Email: michael.dunn@ucd.ie

Publications

Books

Van Eyk J, Dunn MJ; (2008) Clinical Proteomics: From Diagnosis to Therapy. Weinheim: Wiley-VCH. [Details]
Penning SR, Dunn MJ; (2000) Proteomics: From Protein Sequence to Function. Oxford: Bios. [Details]
Dunn MJ; (1999) From Genome to Proteome: Advances in the Parctice and Application of Proteomics. Weinheim: Wiley-VCH. [Details]
Jorde, L.B., Little, P.F.R., Dunn, M.J., Subramaniam, S.; (2005) Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. Chichester: Wiley. [Details]
Van Eyk JE and Dunn MJ (Eds) ; (2002) Proteomic Analysis of Cardiovascular Disease. Weinheim: Wiley-VCH. [Details]
Dunn MJ (Editor) ; (2001) Proteomics Reviews 2001. Weinheim: Wiley-VCH. [Details]

Book Chapters

Focking M, Pennington K, English J, Dunn MJ, Cotter D; (2008) 'Proteomics provides insights into major psychiatric disorders' In: Clinical Proteomics: From Diagnosis to Therapy. Weinheim: Wiley-VCH. [Details]
Donoghue P, Stastna M, Dunn MJ; (2008) 'Protein separation by two-dimensional electrophoresis' In: Eyk JE, Dunn MJ (eds). Clinical Proteomics: From Diagnosis to Therapy. Weinheim: Wiley-VCH. [Details]
McManus C, Rose ML, Dunn MJ; (2008) 'Diagnostic markers for monitoring heart transplant rejection' In: Clinical Proteomics: From Diagnosis to Therapy. Weinheim: Wiley-VCH. [Details]
McGregor, E Dunn, M.J.; (2006) 'Proteomics of the microvasculature' In: Microvascular Research. New York: Elsevier. [Details]
Dowsey, A.W., Yang, G.Z., Dunn, M.J.; (2006) 'Image analysis' In: Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. Chichester: Wiley. [Details]
Dunn, M.J., Pennington, S.R.; (2006) 'Separation-dependent approaches for protein expression profiling' In: Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. Chichester: Wiley. [Details]
Görg, A., Dunn, M.J., Weiss, W.; (2006) 'Two-dimensional gel electrophoresis' In: Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. Chichester: Wiley. [Details]
McGregor, E., Dunn, M.J.; (2006) 'Two-dimensional gel electrophoresis (2-DE)' In: Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. Chichester: Wiley. [Details]
 

Peer Reviewed Journals

Behan, A. T.,Byrne, C.,Dunn, M. J.,Cagney, G.,Cotter, D. R.; (2009) 'Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression'. Mol Psychiatry, 14 (6):601-13. Available Online [Details]
Pennington, K.,Focking, M.,McManus, C. A.,Pariante, C. M.,Dunn, M. J.,Cotter, D. R.; (2009) 'A proteomic investigation of similarities between conventional and herbal antidepressant treatments'. J Psychopharmacol, 23 (5):520-30. Available Online [Details]
McManus, C. A.,Donoghue, P. M.,Dunn, M. J.; (2009) 'A fluorescent codetection system for immunoblotting and proteomics through ECL-Plex and CyDye labeling'. Methods Mol Biol, 536 :515-26. Available Online [Details]
Eisenacher, M.,Martens, L.,Hardt, T.,Kohl, M.,Barsnes, H.,Helsens, K.,Hakkinen, J.,Levander, F.,Aebersold, R.,Vandekerckhove, J.,Dunn, M. J.,Lisacek, F.,Siepen, J. A.,Hubbard, S. J.,Binz, P. A.,Bluggel, M.,Thiele, H.,Cottrell, J.,Meyer, H. E.,Apweiler, R.,Stephan, C.; (2009) 'Getting a grip on proteomics data - Proteomics Data Collection (ProDaC)'. Proteomics, 9 (15):3928-33. Available Online [Details]
Trott, D.,McManus, C. A.,Martin, J. L.,Brennan, B.,Dunn, M. J.,Rose, M. L.; (2009) 'Effect of phosphorylated hsp27 on proliferation of human endothelial and smooth muscle cells'. Proteomics, 9 (12):3383-94. Available Online [Details]
Govender P, Dunn MJ, Donnelly SC ; (2009) 'Proteomics and the lung: Analysis of bronchoalveolar lavage fluid'. Proteomics Clinical Applications, 2 :1044-1051. [Details]
Bell AW et al. ; (2009) 'A HUPO test sample study reveals common problems in mass spectrometry-based proteomics'. Nature Methods, 6 :423-430. [Details]
Munkonge, F. M.,Amin, V.,Hyde, S. C.,Green, A. M.,Pringle, I. A.,Gill, D. R.,Smith, J. W.,Hooley, R. P.,Xenariou, S.,Ward, M. A.,Leeds, N.,Leung, K. Y.,Chan, M.,Hillery, E.,Geddes, D. M.,Griesenbach, U.,Postel, E. H.,Dean, D. A.,Dunn, M. J.,Alton, E. W.; (2009) 'Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import'. J Biol Chem, 284 (39):26978-87. Available Online [Details]
Rose, M. L.,Dunn, M. J.; (2009) 'Biomarkers of rejection: are we any closer to the Philosopher's Stone?'. Transplantation, 88 (4):453-4. Available Online [Details]
Robinson, A. A.,Westbrook, J. A.,English, J. A.,Boren, M.,Dunn, M. J.; (2009) 'Assessing the use of thermal treatment to preserve the intact proteomes of post-mortem heart and brain tissue'. Proteomics, 9 (19):4433-44. Available Online [Details]
English, J. A.,Dicker, P.,Focking, M.,Dunn, M. J.,Cotter, D. R.; (2009) '2-D DIGE analysis implicates cytoskeletal abnormalities in psychiatric disease'. Proteomics, 9 (12):3368-82. Available Online [Details]
Westbrook, J. A., Leong, H., Ghimire, G., Podor, T., Dalby, M., Rose, M. L., Dunn, M. J., Polden, J., ; (2008) 'Problem of resistance to thrombolytic therapy after acute myocardial infarction: A proteomic approach'. Heart, 94 (9). [Details]
Dunn MJ, Donoghue PM, Hughes C, Vissers JP, Langridge JI, ; (2008) 'Nonionic detergent phase extraction for the proteomic analysis of heart membrane proteins using label-free LC-MS'. Proteomics, 8 (18):3895-3905. [DOI] [Details]
Rabilloud T, Dunn MJ, Gil C, Kleinhammer C, Lottspeich F, Pennington S, Sanchez JC, Albar JP, Bini L, Corrales F, Corthals GL, Fountoulakis MM, Hoogland C, James P, Jensen ON, Jiménez C, Jorrín-Novo J, Kraus HJ, Meyer H, Noukakis D, Palagi PM, Penque D, Quinn A, ; (2008) 'EuPA achieves visibility - an activity report on the first three years'. Proteomics, 71 (1):11-18. [DOI] [Details]
Yang GZ, Dowsey AW, Dunn MJ, ; (2008) 'Automated image alignment for 2D gel electrophoresis in a high-throughput proteomics pipeline'. Bioinformatics, 24 (7):950-957. [DOI] [Details]
Cotter DR, Behan A, Byrne C, Dunn MJ, Cagney G, ; (2008) 'Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression'. Molecular psychiatry, . [DOI] [Details]
Vondriska TM, Warburton S, White MY, Van Eyk JE, Cotter RJ, Ping P, Dunn MJ, ; (2008) 'Cardiovascular Initiative of the Human Proteome Organisation, 5th Workshop October 2007, Seoul, Korea'. Proteomics, 8 (5):924-926. [DOI] [Details]
Bell, J. R., Kennington, E., Fuller, W., Dighe, K., Donoghue, P., Clark, J. E., Jia, L. G., Tucker, A. L., Moorman, J. R., Marber, M. S., Eaton, P., Dunn, M. J., Shattock, M. J., ; (2008) 'Characterization of the phospholemman knockout mouse heart: depressed left ventricular function with increased Na-K-ATPase activity'. American Journal of Physiology-Heart and Circulatory Physiology, 294 (2):613-621. [Details]
Dunn, M. J.,Gil, C.,Kleinhammer, C.,Lottspeich, F.,Pennington, S.,Sanchez, J. C.,Albar, J. P.,Bini, L.,Corrales, F.,Corthals, G. L.,Fountoulakis, M. M.,Hoogland, C.,James, P.,Jensen, O. N.,Jimenez, C.,Jorrin-Novo, J.,Kraus, H. J.,Meyer, H.,Noukakis, D.,Palagi, P. M.,Penque, D.,Quinn, A.,Rabilloud, T.; (2008) 'EuPA achieves visibility - an activity report on the first three years'. J Proteomics, 71 (1):11-8. Available Online [Details]
Warburton, S.,White, M. Y.,Van Eyk, J. E.,Cotter, R. J.,Ping, P.,Dunn, M. J.,Vondriska, T. M.; (2008) 'Cardiovascular Initiative of the Human Proteome Organisation, 5th Workshop October 2007, Seoul, Korea'. Proteomics, 8 (5):924-6. Available Online [Details]
Dowsey, A. W.,Dunn, M. J.,Yang, G. Z.; (2008) 'Automated image alignment for 2D gel electrophoresis in a high-throughput proteomics pipeline'. Bioinformatics, 24 (7):950-7. Available Online [Details]
Donoghue, P. M.,Hughes, C.,Vissers, J. P.,Langridge, J. I.,Dunn, M. J.; (2008) 'Nonionic detergent phase extraction for the proteomic analysis of heart membrane proteins using label-free LC-MS'. Proteomics, 8 (18):3895-905. Available Online [Details]
Radwan, M.,Miller, I.,Grunert, T.,Marchetti-Deschmann, M.,Vogl, C.,O'Donoghue, N.,Dunn, M. J.,Kolbe, T.,Allmaier, G.,Gemeiner, M.,Muller, M.,Strobl, B.; (2008) 'The impact of tyrosine kinase 2 (Tyk2) on the proteome of murine macrophages and their response to lipopolysaccharide (LPS)'. Proteomics, 8 (17):3469-85. Available Online [Details]
Mathivanan, S.,Ahmed, M.,Ahn, N. G.,Alexandre, H.,Amanchy, R.,Andrews, P. C.,Bader, J. S.,Balgley, B. M.,Bantscheff, M.,Bennett, K. L.,Bjorling, E.,Blagoev, B.,Bose, R.,Brahmachari, S. K.,Burlingame, A. S.,Bustelo, X. R.,Cagney, G.,Cantin, G. T.,Cardasis, H. L.,Celis, J. E.,Chaerkady, R.,Chu, F.,Cole, P. A.,Costello, C. E.,Cotter, R. J.,Crockett, D.,DeLany, J. P.,De Marzo, A. M.,DeSouza, L. V.,Deutsch, E. W.,Dransfield, E.,Drewes, G.,Droit, A.,Dunn, M. J.,Elenitoba-Johnson, K.,Ewing, R. M.,Van Eyk, J.,Faca, V.,Falkner, J.,Fang, X.,Fenselau, C.,Figeys, D.,Gagne, P.,Gelfi, C.,Gevaert, K.,Gimble, J. M.,Gnad, F.,Goel, R.,Gromov, P.,Hanash, S. M.,Hancock, W. S.,Harsha, H. C.,Hart, G.,Hays, F.,He, F.,Hebbar, P.,Helsens, K.,Hermeking, H.,Hide, W.,Hjerno, K.,Hochstrasser, D. F.,Hofmann, O.; (2008) 'Human Proteinpedia enables sharing of human protein data'. Nat Biotechnol, 26 (2):164-7. Available Online [Details]
Byrne, J. C.,Downes, M. R.,O'Donoghue, N.,Fitzpatrick, J. M.,Dunn, M. J.,Watson, R. W.; (2008) 'Fasting status as a consideration for human serum collection and preparation prior to depletion and analysis'. Electrophoresis, 29 (14):3055-9. Available Online [Details]
Pennington, K.,Dicker, P.,Dunn, M. J.,Cotter, D. R.; (2008) 'Proteomic analysis reveals protein changes within layer 2 of the insular cortex in schizophrenia'. Proteomics, 8 (23-24):5097-107. Available Online [Details]
Shattock MJ, Bell JR, Kennington E, Fuller W, Dighe K, Donoghue P, Clark JE, Jia LG, Tucker AL, Moorman JR, Marber MS, Eaton P, Dunn MJ, ; (2008) 'Characterization of the phospholemman knockout mouse heart: depressed left ventricular function with increased Na-K-ATPase activity'. The Journal of physiology, 294 (2):1-21. [DOI] [Details]
Pandey A et al.; (2008) 'Human Proteinpedia enables sharing of human protein data'. Nature biotechnology, 26 (2):164-167. [DOI] [Details]
Dunn MJ, ; (2008) 'PROTEOMICS Reviews 2008'. Proteomics, 8 (4):608-611. [DOI] [Details]
Strobl B, Radwan M, Miller I, Grunert T, Marchetti-Deschmann M, Vogl C, O'Donoghue N, Dunn MJ, Kolbe T, Allmaier G, Gemeiner M, Müller M, ; (2008) 'The impact of tyrosine kinase 2 (Tyk2) on the proteome of murine macrophages and their response to lipopolysaccharide (LPS)'. Proteomics, 8 (17):3469-3485. [DOI] [Details]
Cotter DR, Pennington K, Föcking M, McManus CA, Pariante CM, Dunn MJ, ; (2008) 'A proteomic investigation of similarities between conventional and herbal antidepressant treatments'. Journal of psychopharmacology (Oxford, England), . [DOI] [Details]
Pennington, K, Beasley, C, Dicker, P, Hudson, L, Dunn, MJ, Cotter, DR, ; (2007) 'Evidence for the involvement of the septin family in schizophrenia and bipolar disorder: A proteomic investigation of the dorsolateral prefrontal cortex'. SCHIZOPHRENIA BULL, 33 :265-266. [Details]
Ohlendieck K, Donoghue P, Doran P, Wynne K, Pedersen K, Dunn MJ, ; (2007) 'Proteomic profiling of chronic low-frequency stimulated fast muscle'. Proteomics, 7 (18):3417-3430. [DOI] [Details]
Westbrook JA, Lafranchi-Tristem N, Dunn MJ, Cieslak A, Vogler AP, ; (2007) 'Investigation of hormone activity in butterfly imaginal wing discs by protein expression pattern changes'. Electrophoresis, 28 (4):535-544. [DOI] [Details]
Dunn MJ, Rose ML, ; (2007) 'Letter by Rose and Dunn regarding article, Expression of heat shock protein 27 in human atherosclerotic plaques and increased plasma level of heat shock protein 27 in patients with acute coronary syndrome'. Circulation, 115 (17). [DOI] [Details]
Hermjakob H, Taylor CF, Paton NW, Lilley KS, Binz PA, Julian RK Jr, Jones AR, Zhu W, Apweiler R, Aebersold R, Deutsch EW, Dunn MJ, Heck AJ, Leitner A, Macht M, Mann M, Martens L, Neubert TA, Patterson SD, Ping P, Seymour SL, Souda P, Tsugita A, Vandekerckhove J, Vondriska TM, Whitelegge JP, Wilkins MR, Xenarios I, Yates JR 3rd, ; (2007) 'The minimum information about a proteomics experiment (MIAPE)'. Nature biotechnology, 25 (8):887-893. [DOI] [Details]
Dunn MJ, ; (2007) 'Two-dimensional polyacrylamide gel electrophoresis for cardiovascular proteomics'. Methods in molecular biology (Clifton, N.J.), 357 :3-13. [DOI] [Details]
Cotter DR, Pennington K, Beasley CL, Dicker P, Fagan A, English J, Pariante CM, Wait R, Dunn MJ, ; (2007) 'Prominent synaptic and metabolic abnormalities revealed by proteomic analysis of the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder'. Molecular psychiatry, . [DOI] [Details]
Cotter, D, English, J, Dicker, P, Wait, R, Dunn, M, ; (2007) 'Characterising pre and post-mortem factors influencing human post-mortem brain proteomic studies'. SCHIZOPHRENIA BULL, 33 :258-258. [Details]
Foecking, M, Hudson, L, Dunn, M, Cotter, D, ; (2007) 'Proteomic analysis of hippocampal subregions in schizophrenia and bipolar disorder'. SCHIZOPHRENIA BULL, 33 :260-260. [Details]
English, J, Dicker, P, Wait, R, ODonoghue, N, Pennington, S, Dunn, M, Cotter, D, ; (2007) 'Proteomic analysis of white matter from the dorsolateral prefrontal cortex in schizophrenia demonstrated alterations in synaptic associated proteins'. SCHIZOPHRENIA BULL, 33 :259-260. [Details]
Eaton P, Brennan JP, Miller JI, Fuller W, Wait R, Begum S, Dunn MJ, ; (2006) 'The utility of N,N-biotinyl glutathione disulfide in the study of protein S-glutathiolation'. Proteomics, 5 (2):215-225. [DOI] [Details]
Dunn MJ, Wilkins MR, Appel RD, Van Eyk JE, Chung MC, Görg A, Hecker M, Huber LA, Langen H, Link AJ, Paik YK, Patterson SD, Pennington SR, Rabilloud T, Simpson RJ, Weiss W, ; (2006) 'Guidelines for the next 10 years of proteomics'. Proteomics, 6 (1):4-8. [DOI] [Details]
Emery PW, Zhou S, Mann CJ, Dunn MJ, Preedy VR, ; (2006) 'Measurement of specific radioactivity in proteins separated by two-dimensional gel electrophoresis'. Electrophoresis, 27 (5-6):1147-1153. [DOI] [Details]
Dunn MJ, McGregor E, ; (2006) 'Proteomics of the heart: unraveling disease'. Circulation Research, 98 (3):309-321. [DOI] [Details]
Apweiler R, Hamacher M, Stephan C, Blüggel M, Chamrad D, Körting G, Martens L, Müller M, Hermjakob H, Parkinson D, Dowsey A, Reidegeld KA, Marcus K, Dunn MJ, Meyer HE, ; (2006) 'The HUPO Brain Proteome Project jamboree: centralised summary of the pilot studies'. Proteomics, 6 (6):1719-1721. [DOI] [Details]
Donoghue, P. M.,McManus, C. A.,O'Donoghue, N. M.,Pennington, S. R.,Dunn, M. J.; (2006) 'CyDye immunoblotting for proteomics: co-detection of specific immunoreactive and total protein profiles'. Proteomics, 6 (24):6400-4. [Details]
Emery PW, Zhou S, Bailey MJ, Dunn MJ, Preedy VR, ; (2005) 'A quantitative investigation into the losses of proteins at different stages of a two-dimensional gel electrophoresis procedure'. Proteomics, 5 (11):2739-2747. [DOI] [Details]
Rose ML, De Souza AI, Wait R, Mitchell AG, Banner NR, Dunn MJ, ; (2005) 'Heat shock protein 27 is associated with freedom from graft vasculopathy after human cardiac transplantation'. Circulation Research, 97 (2):192-198. [DOI] [Details]
Dunn MJ, Pennington K, Cotter D, ; (2005) 'The role of proteomics in investigating psychiatric disorders'. British Journal of Psychiatry, 187 :4-6. [DOI] [Details]
Powell JT, McGregor E, Kempster L, Wait R, Gosling M, Dunn MJ, ; (2004) 'F-actin capping (CapZ) and other contractile saphenous vein smooth muscle proteins are altered by hemodynamic stress: a proteonomic approach'. Proteomics, 3 (2):115-124. [DOI] [Details]
Archard LC, Zhang H, Li Y, McClean DR, Richardson PJ, Florio R, Sheppard M, Morrison K, Latif N, Dunn MJ, ; (2004) 'Detection of enterovirus capsid protein VP1 in myocardium from cases of myocarditis or dilated cardiomyopathy by immunohistochemistry: further evidence of enterovirus persistence in myocytes'. Medical microbiology and immunology, 193 (2-3):109-114. [DOI] [Details]
Emery PW, Zhou S, Bailey MJ, Dunn MJ, Preedy VR, ; (2004) 'A systematic investigation into the recovery of radioactively labeled proteins from sodium dodecyl sulfate-polyacrylamide gels'. Electrophoresis, 25 (1):1-7. [DOI] [Details]
Dunn MJ, Pennington K, McGregor E, Beasley CL, Everall I, Cotter D, ; (2004) 'Optimization of the first dimension for separation by two-dimensional gel electrophoresis of basic proteins from human brain tissue'. Proteomics, 4 (1):27-30. [DOI] [Details]
Bevan CL, Gamble SC, Odontiadis M, Waxman J, Westbrook JA, Dunn MJ, Wait R, Lam EW, ; (2004) 'Androgens target prohibitin to regulate proliferation of prostate cancer cells'. Oncogene, 23 (17):2996-3004. [DOI] [Details]
Dunn MJ, ; (2004) 'Electroelution of proteins from polyacrylamide gels'. Methods in molecular biology (Clifton, N.J.), 244 :339-343. [Details]
Dunn MJ, ; (2004) 'Electroblotting of proteins from polyacrylamide gels'. Methods in molecular biology (Clifton, N.J.), 244 :345-352. [Details]
Rose ML, De Souza AI, McGregor E, Dunn MJ, ; (2004) 'Preparation of human heart for laser microdissection and proteomics'. Proteomics, 4 (3):578-586. [DOI] [Details]
Rose ML, Borozdenkova S, Westbrook JA, Patel V, Wait R, Bolad I, Burke MM, Bell AD, Banner NR, Dunn MJ, ; (2004) 'Use of proteomics to discover novel markers of cardiac allograft rejection'. Journal of Proteome Research, 3 (2):282-288. [Details]
Dunn MJ, ; (2004) 'Viewpoint Articles--a new category of scientific contribution in PROTEOMICS'. Proteomics, 4 (7). [DOI] [Details]
Xu Q, Mayr M, Chung YL, Mayr U, McGregor E, Troy H, Baier G, Leitges M, Dunn MJ, Griffiths JR, ; (2004) 'Loss of PKC-delta alters cardiac metabolism'. The Journal of physiology, 287 (2):1-45. [DOI] [Details]
Xu Q, Mayr M, Metzler B, Chung YL, McGregor E, Mayr U, Troy H, Hu Y, Leitges M, Pachinger O, Griffiths JR, Dunn MJ, ; (2004) 'Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice'. The Journal of physiology, 287 (2):1-56. [DOI] [Details]
Eaton P, Brennan JP, Wait R, Begum S, Bell JR, Dunn MJ, ; (2004) 'Detection and mapping of widespread intermolecular protein disulfide formation during cardiac oxidative stress using proteomics with diagonal electrophoresis'. Journal of Biological Chemistry, 279 (40):41352-41360. [DOI] [Details]
Yang GZ, Dowsey AW, Dunn MJ, ; (2004) 'ProteomeGRID: towards a high-throughput proteomics pipeline through opportunistic cluster image computing for two-dimensional gel electrophoresis'. Proteomics, 4 (12):3800-3812. [DOI] [Details]
Dunn MJ, Görg A, Weiss W, ; (2004) 'Current two-dimensional electrophoresis technology for proteomics'. Proteomics, 4 (12):3665-3685. [DOI] [Details]
Dunn MJ, McGregor E, ; (2003) 'Proteomics of heart disease'. Human Molecular Genetics, 12 Spec No 2 :1-44. [DOI] [Details]
Tomley F, Bromley E, Leeds N, Clark J, McGregor E, Ward M, Dunn MJ, ; (2003) 'Defining the protein repertoire of microneme secretory organelles in the apicomplexan parasite Eimeria tenella'. Proteomics, 3 (8):1553-1561. [DOI] [Details]
Pusey CD, Evans DJ, Macanovic M, Dunn MJ, ; (2003) 'Membranous glomerulonephritis associated with follicular B-cell lymphoma and subepithelial deposition of IgG1-kappa paraprotein'. Nephron. Clinical practice, 93 (3):1-8. [DOI] [Details]
Dunn MJ, Weekes J, Morrison K, Mullen A, Wait R, Barton P, ; (2003) 'Hyperubiquitination of proteins in dilated cardiomyopathy'. Proteomics, 3 (2):208-216. [DOI] [Details]
Dunn MJ, ; (2003) 'Two-dimensional polyacrylamide gel electrophoresis for the separation of proteins for chemical characterization'. Methods in molecular biology (Clifton, N.J.), 211 :31-39. [Details]
Dunn MJ, ; (2003) 'Electroblotting of proteins from polyacrylamide gels for chemical characterization'. Methods in molecular biology (Clifton, N.J.), 211 :41-48. [Details]
Dunn MJ, Weekes J, Watson RR, ; (2003) 'Murine retrovirus infection and the effect of chronic alcohol consumption: proteomic analysis of cardiac protein expression'. Alcohol and Alcoholism, 38 (2):103-108. [Details]
Shattock MJ, Eaton P, Jones ME, McGregor E, Dunn MJ, Leeds N, Byers HL, Leung KY, Ward MA, Pratt JR, ; (2003) 'Reversible cysteine-targeted oxidation of proteins during renal oxidative stress'. Journal of the American Society of Nephrology, 14 (8 Suppl 3):1-6. [Details]
Yang GZ, Dowsey AW, Dunn MJ, ; (2003) 'The role of bioinformatics in two-dimensional gel electrophoresis'. Proteomics, 3 (8):1567-1596. [DOI] [Details]
Dunn MJ, Dos Remedios CG, Liew CC, Allen PD, Winslow RL, Van Eyk JE, ; (2003) 'Genomics, proteomics and bioinformatics of human heart failure'. Cell, 24 (4-6):251-260. [Details]
Copp AJ, Greene ND, Leung KY, Wait R, Begum S, Dunn MJ, ; (2002) 'Differential protein expression at the stage of neural tube closure in the mouse embryo'. Journal of Biological Chemistry, 277 (44):41645-41651. [DOI] [Details]
Kuhl U, Warraich RS, Noutsias M, Kazak I, Seeberg B, Dunn MJ, Schultheiss HP, Yacoub MH, ; (2002) 'Immunoglobulin G3 cardiac myosin autoantibodies correlate with left ventricular dysfunction in patients with dilated cardiomyopathy: immunoglobulin G3 and clinical correlates'. American Heart Journal, 143 (6):1076-1084. [Details]
Slabas AR, Maltman DJ, Simon WJ, Wheeler CH, Dunn MJ, Wait R, ; (2002) 'Proteomic analysis of the endoplasmic reticulum from developing and germinating seed of castor (Ricinus communis)'. Electrophoresis, 23 (4):626-639. [DOI] [Details]
Dunn MJ, Yan JX, Harry RA, Wait R, Welson SY, Emery PW, Preedy VR, ; (2001) 'Separation and identification of rat skeletal muscle proteins using two-dimensional gel electrophoresis and mass spectrometry'. Proteomics, 1 (3):424-434. [DOI] [Details]
Dunn MJ, Leung KY, Wait R, Welson SY, Yan JX, Abraham DJ, Black CM, Pearson JD, ; (2001) 'A reference map of human lung MRC-5 fibroblast proteins using immobilized pH gradient-isoelectric focusing-based two-dimensional electrophoresis'. Proteomics, 1 (6):787-794. [DOI] [Details]
Dunn MJ, Westbrook JA, Yan JX, Wait R, Welson SY, ; (2001) 'Zooming-in on the proteome: very narrow-range immobilised pH gradients reveal more protein species and isoforms'. Electrophoresis, 22 (14):2865-2871. [DOI] [Details]
Rose ML, Jurcevic S, Ainsworth ME, Pomerance A, Smith JD, Robinson DR, Dunn MJ, Yacoub MH, ; (2001) 'Antivimentin antibodies are an independent predictor of transplant-associated coronary artery disease after cardiac transplantation'. Transplantation, 71 (7):886-892. [Details]
Yang GZ, Veeser S, Dunn MJ, ; (2001) 'Multiresolution image registration for two-dimensional gel electrophoresis'. Proteomics, 1 (7):856-870. [DOI] [Details]
Miller I, Wait R, Gianazza E, Eberini I, Sironi L, Dunn MJ, Gemeiner M, ; (2001) 'Proteins of rat serum, urine, and cerebrospinal fluid: VI. Further protein identifications and interstrain comparison'. Electrophoresis, 22 (14):3043-3052. [DOI] [Details]
Dunn MJ, Westbrook JA, Yan JX, Wait R, ; (2001) 'A combined radiolabelling and silver staining technique for improved visualisation, localisation, and identification of proteins separated by two-dimensional gel electrophoresis'. Proteomics, 1 (3):370-376. [DOI] [Details]
Nosworthy NJ, Jiang L, Tsubakihara M, Heinke MY, Yao M, Dunn MJ, Phillips W, dos Remedios CG, ; (2001) 'Heart failure and apoptosis: electrophoretic methods support data from micro- and macro-arrays. A critical review of genomics and proteomics'. Proteomics, 1 (12):1481-1488. [Details]
Cherry GW, Mensah AY, Sampson J, Houghton PJ, Hylands PJ, Westbrook J, Dunn M, Hughes MA, ; (2001) 'Effects of Buddleja globosa leaf and its constituents relevant to wound healing'. Journal of ethnopharmacology, 77 (2-3):219-226. [Details]
Powel JT, McGregor E, Kempster L, Wait R, Welson SY, Gosling M, Dunn MJ, ; (2001) 'Identification and mapping of human saphenous vein medial smooth muscle proteins by two-dimensional polyacrylamide gel electrophoresis'. Proteomics, 1 (11):1405-1414. [DOI] [Details]
Dunn MJ, ; (2000) 'Studying heart disease using the proteomic approach'. Drug Discovery Today, 5 (2):76-84. [Details]
Arrand JE, Gamble SC, Dunn MJ, Wheeler CH, Joiner MC, Adu-Poku A, ; (2000) 'Expression of proteins coincident with inducible radioprotection in human lung epithelial cells'. Cancer, 60 (8):2146-2151. [Details]
Yacoub MH, Warraich RS, Pomerance A, Stanley A, Banner NR, Dunn MJ, ; (2000) 'Cardiac myosin autoantibodies and acute rejection after heart transplantation in patients with dilated cardiomyopathy'. Transplantation, 69 (8):1609-1617. [Details]
Yacoub MH, Latif N, Khan MA, Birks E, O'Farrell A, Westbrook J, Dunn MJ, ; (2000) 'Upregulation of the Bcl-2 family of proteins in end stage heart failure'. Journal of the American College of Cardiology, 35 (7):1769-1777. [Details]
Preedy VR, Patel VB, Sandhu G, Corbett JM, Dunn MJ, Rodrigues LM, Griffiths JR, Wassif W, Sherwood RA, Richardson PJ, ; (2000) 'A comparative investigation into the effect of chronic alcohol feeding on the myocardium of normotensive and hypertensive rats: an electrophoretic and biochemical study'. Electrophoresis, 21 (12):2454-2462. [DOI] [Details]
Preedy VR, Patel VB, Sandhu G, Dunn MJ, Mantle D, Rodrigues LM, Griffiths JR, Wassif W, Richardson PJ, ; (2000) 'Poor regression of myocardial hypertrophy following concomitant chronic alcohol ingestion and angiotensin converting enzyme (ACE) inhibition'. Life Sciences, 67 (12):1409-1421. [Details]
Selby PJ, Banks RE, Dunn MJ, Hochstrasser DF, Sanchez JC, Blackstock W, Pappin DJ, ; (2000) 'Proteomics: new perspectives, new biomedical opportunities'. Lancet, 356 (9243):1749-1756. [DOI] [Details]
Dunn MJ, Yan JX, Harry RA, Spibey C, ; (2000) 'Postelectrophoretic staining of proteins separated by two-dimensional gel electrophoresis using SYPRO dyes'. Electrophoresis, 21 (17):3657-3665. [DOI] [Details]
Dunn MJ, Yan JX, Wait R, Berkelman T, Harry RA, Westbrook JA, Wheeler CH, ; (2000) 'A modified silver staining protocol for visualization of proteins compatible with matrix-assisted laser desorption/ionization and electrospray ionization-mass spectrometry'. Electrophoresis, 21 (17):3666-3672. [DOI] [Details]
Yacoub M, Petrou M, Clarke S, Morrison K, Bowles C, Dunn M, ; (1999) 'Clenbuterol increases stroke power and contractile speed of skeletal muscle for cardiac assist'. Circulation, 99 (5):713-720. [Details]
Yacoub MH, Warraich RS, Dunn MJ, ; (1999) 'Subclass specificity of autoantibodies against myosin in patients with idiopathic dilated cardiomyopathy: pro-inflammatory antibodies in DCM patients'. Biochemical and Biophysical Research Communications, 259 (2):255-261. [DOI] [Details]
Selby PJ, Banks RE, Dunn MJ, Forbes MA, Stanley A, Pappin D, Naven T, Gough M, Harnden P, ; (1999) 'The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomic analysis--preliminary findings'. Electrophoresis, 20 (4-5):689-700. [DOI] [Details]
Baur X, Posch A, Wheeler CH, Chen Z, Flagge A, Dunn MJ, Papenfuss F, Raulf-Heimsoth M, ; (1999) 'Class I endochitinase containing a hevein domain is the causative allergen in latex-associated avocado allergy'. Clinical Experimental Allergy, 29 (5):667-672. [Details]
Dunn MJ, ; (1999) 'Detection of total proteins on western blots of 2-D polyacrylamide gels'. Methods in molecular biology (Clifton, N.J.), 112 :319-329. [Details]
Dunn MJ, ; (1999) 'Electroblotting of proteins from 2-D polyacrylamide gels'. Methods in molecular biology (Clifton, N.J.), 112 :313-318. [Details]
Dunn MJ, Latif N, Zhang H, Archard LC, Yacoub MH, ; (1999) 'Characterization of anti-heart antibodies in mice after infection with coxsackie B3 virus'. Clinical Immunology, 91 (1):90-98. [DOI] [Details]
Dunn MJ, Latif N, Taylor PM, Khan MA, Yacoub MH, ; (1999) 'The expression of heat shock protein 60 in patients with dilated cardiomyopathy'. Basic research in cardiology, 94 (2):112-119. [Details]
Dunn MJ, Weekes J, Wheeler CH, Yan JX, Weil J, Eschenhagen T, Scholtysik G, ; (1999) 'Bovine dilated cardiomyopathy: proteomic analysis of an animal model of human dilated cardiomyopathy'. Electrophoresis, 20 (4-5):898-906. [DOI] [Details]
dos Remedios CG, Heinke MY, Wheeler CH, Yan JX, Amin V, Chang D, Einstein R, Dunn MJ, ; (1999) 'Changes in myocardial protein expression in pacing-induced canine heart failure'. Electrophoresis, 20 (10):2086-2093. [DOI] [Details]
Nelson DR, Faulk WP, Rose M, Meroni PL, Del Papa N, Torry RJ, Labarrere CA, Busing K, Crisp SJ, Dunn MJ, ; (1999) 'Antibodies to endothelial cells identify myocardial damage and predict development of coronary artery disease in patients with transplanted hearts'. Human immunology, 60 (9):826-832. [Details]
Jungblut PR, Scheler C, Li XP, Salnikow J, Dunn MJ, ; (1999) 'Comparison of two-dimensional electrophoresis patterns of heat shock protein Hsp27 species in normal and cardiomyopathic hearts'. Electrophoresis, 20 (18):3623-3628. [DOI] [Details]
Dunn MJ, Corbett JM, Why HJ, Wheeler CH, Richardson PJ, Archard LC, Yacoub MH, ; (1998) 'Cardiac protein abnormalities in dilated cardiomyopathy detected by two-dimensional polyacrylamide gel electrophoresis'. Electrophoresis, 19 (11):2031-2042. [DOI] [Details]
Hochstrasser DF, Wilkins MR, Gasteiger E, Wheeler CH, Lindskog I, Sanchez JC, Bairoch A, Appel RD, Dunn MJ, ; (1998) 'Multiple parameter cross-species protein identification using MultiIdent--a world-wide web accessible tool'. Electrophoresis, 19 (18):3199-3206. [DOI] [Details]
Boheler KR, Boateng SY, Seymour AM, Bhutta NS, Dunn MJ, Yacoub MH, ; (1998) 'Sub-antihypertensive doses of ramipril normalize sarcoplasmic reticulum calcium ATPase expression and function following cardiac hypertrophy in rats'. Cell, 30 (12):2683-2694. [DOI] [Details]
Yacoub MH, Amrani M, Latif N, Morrison K, Gray CC, Jayakumar J, Corbett J, Goodwin AT, Dunn MJ, ; (1998) 'Relative induction of heat shock protein in coronary endothelial cells and cardiomyocytes: implications for myocardial protection'. The Journal of thoracic and cardiovascular surgery, 115 (1):200-209. [Details]
dos Remedios CG, Heinke MY, Wheeler CH, Chang D, Einstein R, Drake-Holland A, Dunn MJ, ; (1998) 'Protein changes observed in pacing-induced heart failure using two-dimensional electrophoresis'. Electrophoresis, 19 (11):2021-2030. [DOI] [Details]
Yacoub MH, Cunningham DA, Crisp SJ, Barbir M, Lazem F, Dunn MJ, ; (1998) 'Donor ACE gene polymorphism: a genetic risk factor for accelerated coronary sclerosis following cardiac transplantation'. European Heart Journal, 19 (2):319-325. [Details]
Rose ML, Jurcevic S, Dunn MJ, Crisp S, Busing K, Rinaldi M, Pellegrini C, Yacoub MH, Vigano M, Banner NL, ; (1998) 'A new enzyme-linked immunosorbent assay to measure anti-endothelial antibodies after cardiac transplantation demonstrates greater inhibition of antibody formation by tacrolimus compared with cyclosporine'. Transplantation, 65 (9):1197-1202. [Details]
Baur X, Posch A, Chen Z, Dunn MJ, Wheeler CH, Petersen A, Leubner-Metzger G, ; (1997) 'Latex allergen database'. Electrophoresis, 18 (15):2803-2810. [DOI] [Details]
Wheeler CH, Dunn MJ, Corbett JM, ; (1997) 'HSC-2DPAGE and the two-dimensional gel electrophoresis database of dog heart proteins'. Electrophoresis, 18 (15):2795-2802. [DOI] [Details]
Preedy VR, Patel VB, Corbett JM, Dunn MJ, Winrow VR, Portmann B, Richardson PJ, ; (1997) 'Protein profiling in cardiac tissue in response to the chronic effects of alcohol'. Electrophoresis, 18 (15):2788-2794. [DOI] [Details]
Govender P, Baugh JA, Pennington SR, Dunn MJ, Donnelly SC.; (2007) 'Role of proteomics in the investigation of pulmonary fibrosis'. Expert Rev Proteomics, 4 (3):379-388. [Details]
Rose ML, Dunn MJ.; (2007) 'Expression of heat shock protein 27 in human atherosclerotic plaques and increased plasma level of heat shock protein 27 in patients with acute coronary syndrome'. Circulation, 115 (17):434-435. [Details]
Donoghue PM, McManus CA, O'Donoghue NM, Pennington SR, Dunn MJ.; (2006) 'CyDye immunoblotting for proteomics: co-detection of specific immunoreactive and total protein profiles'. Proteomics, 6 (24):6400-6404. [Details]
Hamacher, M; Stephan, C; Bluggel, M; Chamrad, D; Korting, G; Martens, L; Muller, M; Hermjakob, H; Parkinson, D; Dowsey, A; Reidegeld, KA; Marcus, K; Dunn, MJ; Meyer, HE; Apweiler, R; ; (2006) 'The HUPO Brain Proteome Project Jamboree: Centralised summary of the pilot studies'. Proteomics, 6 (6):1719-1721. [Details]
Beasley, CL; Pennington, K; Behan, A; Wait, R; Dunn, MJ; Cotter, D; ; (2006) 'Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: Evidence for disease-associated changes'. Proteomics, 6 (11):3414-3425. [Details]
Pennington, K; Dunn, M; Cotter, DR; ; (2006) 'Cytoarchitectual and proteomic analysis of the insular cortex in schizophrenia'. Schizophrenia Research, 81 (NA):212-212. [Details]
Focking, M; Boersema, PJ; O'Donoghue, N; Lubec, G; Pennington, SR; Cotter, DR; Dunn, MJ; ; (2006) '2-D DIGE as a quantitative tool for investigating the HUPO Brain Proteome Project mouse series'. Proteomics, 6 (18):4914-4931. [Details]
Hamacher, M; Apweiler, R; Arnold, G; Becker, A; Bluggel, M; Carrette, O; Colvis, C; Dunn, MJ; Frohlich, T; Fountoulakis, M; van Hall, A; Herberg, F; Ji, J; Kretzschmar, H; Lewczuk, P; Lubec, G; Marcus, K; Martens, L; Bustamante, NP; Park, YM; Pennington, SR; Robben, J; Stuhler, K; Reidegeld, KA; Riederer, P; Rossier, J; Sanchez, JC; Schrader, M; Stephan, C; Tagle, D; Thiele, H; Wang, J; Wiltfang, J; Yoo, JS; Zhang, CG; Klose, J; Meyer, HE; ; (2006) 'HUPO Brain Proteome Project: Summary of the pilot phase and introduction of a comprehensive data reprocessing strategy'. Proteomics, 6 (18):4890-4898. [Details]
Gibson, DS; Blelock, S; Curry, J; Healy, A; Dunn, M; Pennington, S; Rooney, ME; ; (2006) 'Identification of proteomic biomarkers to predict progression in juvenile idiopathic arthritis'. Arthritis and Rheumatism, 54 (9):693-693. [Details]
Gibson, DS; Blelock, S; Curry, J; Healy, A; Scaife, C; McAllister, C; Pennington, S; Dunn, M; Rooney, M; ; (2006) 'Biomarkers of disease progression in Juvenile idiopathic arthritis patients'. Molecular & Cellular Proteomics, 5 (10):138-138. [Details]
Downes, MR; Watson, WG; Byrne, JC; Fitzpatrick, JM; Dunn, MJ; Pennington, SR; ; (2006) 'Urinary markers in the diagnosis of prostate cancer'. Molecular & Cellular Proteomics, 5 (10):74-74. [Details]
Dowsey, AW; Dunn, MJ; Yang, GZ; ; (2006) 'ProteomeGRID; A web-based service for high-throughput proteome informatics'. Molecular & Cellular Proteomics, 5 (10):138-138. [Details]
Collins, BC; O'Connor, DP; Currid, CC; O'Donoghue, N; Pedersen, K; Dunn, MJ; Pennington, SR; Roninson, IB; Gallgher, WM; ; (2006) 'Proteomic analysis of cyclin-dependent kinase inhibitor (CDKI)-regulated protein expression in tumour cells via SELDI-TOF-MS and 2D-gel electrophoresis/peptide mass fingerprinting'. Molecular & Cellular Proteomics, 5 (10):101-101. [Details]
Byrne, JC; Brennan, L; Downes, MR; O'Donoghue, N; Fitzpatrick, JM; Dunn, MJ; Watson, RWG; Pennington, SR; ; (2006) 'A combined proteomic and metabolomic analysis of prostate cancer serum samples'. Molecular & Cellular Proteomics, 5 (10):71-71. [Details]
English, J; Dunn, M; Cotter, DR; ; (2006) 'Proteomic analysis of deep white matter from the dorsolateral prefrontal cortex in schizophrenia (SCZ) and bipolar disorder (BPD)'. Schizophrenia Research, 81 (NA):210-210. [Details]
Byrne, J; Downes, M; O'Donoghue, N; Dunn, MJ; Fitzpatrick, JM; Watson, RWG; Pennington, SR; ; (2006) 'Utilising proteomic platforms for the identification of novel serum markers of prostate cancer'. European Urology Supplements, 5 (14):789-789. [Details]
Wilkins, MR; Appel, RD; Van Eyk, JE; Chung, MCM; Gorg, A; Hecker, M; Huber, LA; Langen, H; Link, AJ; Paik, YK; Patterson, SD; Pennington, SR; Rabilloud, T; Simpson, RJ; Weiss, W; Dunn, MJ; ; (2006) 'Guidelines for the next 10 years of proteomics'. Proteomics, 6 (1):4-8. [Details]
Zhou, SB; Mann, CJ; Dunn, MJ; Preedy, VR; Emery, PW; ; (2006) 'Measurement of specific radioactivity in proteins separated by two-dimensional gel electrophoresis'. Electrophoresis, 27 (5-6):1147-1153. [Details]
Chen, RL; Sage, EA; Dunn, MJ; Wait, R; Preston, JE; ; (2006) 'Optimising ovine cerebrospinal fluid preparation for two-dimensional gel electrophoresis'. Proteomics, 6 (10):3170-3175. [Details]
Downes, MR; Byrne, JC; Dunn, MJ; Fitzpatrick, JM; Watson, RWG; Pennington, SR; ; (2006) 'Application of proteomic strategies to the identification of urinary biomarkers for prostate cancer: A review'. Biomarkers, 11 (5):406-416. [Details]
Dowsey, AW; English, J; Pennington, K; Cotter, D; Stuehler, K; Marcus, K; Meyer, HE; Dunn, MJ; Yang, GZ; ; (2006) 'Examination of 2-DE in the Human Proteome Organisation Brain Proteome Project pilot studies with the new RAIN gel matching technique'. Proteomics, 6 (18):5030-5047. [Details]
Brennan, JP; Miller, JIA; Fuller, W; Wait, R; Begum, S; Dunn, MJ; Eaton, P; ; (2006) 'The utility of N,N-biotinyl glutathione disulfide in the study of protein S-glutathiolation'. Molecular & Cellular Proteomics, 5 (2):215-225. [Details]
McGregor, E; Dunn, MJ; ; (2006) 'Proteomics of the heart - Unraveling disease'. Circulation Research, 98 (3):309-321. [Details]
Dunn MJ ; (2006) 'PROTEOMICS - Continued growth and comprehensive coverage'. Proteomics, 6 :1-3. [Details]
Westbrook, JA; Wheeler, JX; Wait, R; Welson, SY; Dunn, MJ; ; (2006) 'The human heart proteome: Two-dimensional maps using narrow-range immobilised pH gradients'. Electrophoresis, 27 (8):1547-1555. [Details]
De Souza AI, Wait R, Mitchell AG, Banner NR, Dunn MJ, Rose ML; (2005) 'Heat shock protein 27 is associated with freedom from graft vasculopathy after human cardiac transplantation'. Circulation Research, 97 :192-198. [Details]
Pennington, K; Cotter, D; Dunn, MJ; ; (2005) 'The role of proteomics in investigating psychiatric disorders'. British Journal of Psychiatry, 187 (NA):4-6. [Details]
Zhou S, Bailey MJ, Dunn MJ, Preedy VR, Emery ; (2005) 'A quantitative investigation into the losses of proteins at different stages of a two-dimensional gel electrophoresis procedure'. Proteomics, 5 :2739-2747. [Details]
Brennan JP, Miller, JIA, Fuller W, Wait R, Begum S, Dunn MJ, Eaton P (; (2005) 'N,N-biotinyl glutathione disulfide: Studies demonstrating its utility in the study of protein S-glutathiolation'. Molecular and Cellular Proteomics, . [Details]
McGregor E, Kempster L, Wait R, Gosling M, Dunn MJ, Powell JT ; (2004) 'F-actin capping (CapZ) and other contractile proteins are altered by hemodynamic stress: A proteomic approach'. Mol. Cell. Proteomics, 3 :115-124. [Details]
Mayr M, Metzler B, Chung YL, McGregor E, Mayr U, Troy H, Hu Y, Leitges M, Pachinger O, Griffiths JR, Dunn MJ, Xu Q. ; (2004) 'Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice'. American Journal of Physiology-Heart and Circulatory Ph, 287 :H946-956. [Details]
Mayr M, Chung YL, Mayr U, McGregor E, Troy H, Baier G, Leitges M, Dunn MJ, Griffiths JR, Xu Q. ; (2004) 'Loss of PKC-delta alters cardiac metabolism'. American Journal of Physiology-Heart and Circulatory Ph, 287 :H937-945. [Details]
Dowsey AW, Dunn MJ, Yang GZ. ; (2004) 'ProteomeGRID: towards a high-throughput proteomics pipeline through opportunistic cluster image computing for two-dimensional gel electrophoresis'. Proteomics, 4 :3800-3812. [Details]
De Souza AI, McGregor E, Dunn MJ, Rose ML; (2004) 'Preparation of human heart for laser microdissection and proteomics'. Proteomics, 4 :578-586. [Details]
Zhou S, Bailey MJ, Dunn MJ, Preedy VR, Emery ; (2004) 'A systematic investigation into the recovery of radioactively labeled proteins from sodium dodecyl sulfate-polyacrylamide gels'. Electrophoresis, 25 :1-7. [Details]
Zhang H, Li Y, McClean DR, Richardson PJ, Florio R, Sheppard M, Morrison K, Latif N, Dunn MJ, Archard LC ; (2004) 'Detection of enterovirus capsid protein VP1 in myocardium from cases of myocarditis or dilated cardiomyopathy by immunohistochemistry: further evidence of enterovirus persistence in myocytes'. Medical Microbiology and Immunology, 193 :109-114. [Details]
McGregor E, Kempster L, Wair R, Gosling M, Dunn MJ, Powell JT ; (2004) 'F-actin capping (CapZ) and other contractile proteins are altered by hemodynamic stress: A proteomic approach'. Molecular and Cellular Proteomics, 3 :115-124. [Details]
Pennington K, McGregor E, Beasley CL, Everall I, Cotter D, Dunn MJ; (2004) 'Optimization of the first dimension for separation by two-dimensional gel electrophoresis of basic proteins from human brain tissue'. Proteomics, 4 :27-30. [Details]
Borozdenkova S, Westbrook JA, Patel V, Wait R, Bolad I, Burke MM, Bell AD, Banner NR, Dunn MJ, Rose ML ; (2004) 'Use of proteomics to discover novel markers of cardiac allograft rejection'. Journal of Proteome Research, 3 :282-288. [Details]
Gorg A, Weiss W, Dunn MJ. ; (2004) 'Current two-dimensional electrophoresis technology for proteomics'. Proteomics, 4 :3665-3685. [Details]
Gamble SC, Odontiadis M, Waxman J, Westbrook JA, Dunn MJ, Wait R, Lam EW, Bevan CL. ; (2004) 'Androgens target prohibitin to regulate proliferation of prostate cancer cells'. Oncogene, 23 :2996-3004. [Details]
Brennan JP, Wait R, Begum S, Bell JR, Dunn MJ, Eaton P. ; (2004) 'Detection and mapping of widespread intermolecular protein disulfide formation during cardiac oxidative stress using proteomics with diagonal electrophoresis'. Journal of Biological Chemistry, 279 :41352-41360. [Details]
Weekes J, Morrison K, Mullen A, Wait R, Barton P and Dunn MJ ; (2003) 'Hyper-ubiquitination of proteins in dilated cardiomyopathy'. Proteomics, 3 :208-216. [Details]
Weekes, J., Watson, R.R., Dunn, M.J; (2003) 'Murine retrovirus infection and the effect of chronic alcohol consumption: Proteomic analysis of cardiac protein expression'. Alcohol and Alcoholism, 38 :103-108. [Details]
Evans DJ, Macanovic M, Dunn MJ, Pusey CD ; (2003) 'Membranous glomerulonephritis with follicular B-cell lymphoma and subepithelial deposition of IgG1-kappa paraprotein'. Nephron Clinical Practice, 93 :112-128. [Details]
Bromley E, Leeds N, Clark J, McGregor E, Ward M, Dunn MJ, Tomley F ; (2003) 'Defining the protein repertoire of microneme secretory organelles in the apicomplexan parasite Eimeria tenella'. Proteomics, 3 :1553-1561. [Details]
Dowsey AW, Dunn MJ, Yang GZ ; (2003) 'The role of bioinformatics in two-dimensional gel electrophoresis'. Proteomics, 3 :1567-1596. [Details]
Banks R, Dunn MJ, Hochstrasser DF, Sanchez JC, Blackstock W, Pappin DJ, Selby PJ ; (2000) 'Proteomics: new perspectives, new biomedical opportunities'. The Lancet, 356 :1749-1756. [Details]
Weekes J, Wheeler CH, Yan JX, Weil J, Eschenhagen T, Scholtysik G, Dunn MJ; (1999) 'Bovine dilated cardiomyopathy: Proteomic analysis of an animal model of human dilated cardiomyopathy'. Electrophoresis, 20 :898-906. [Details]
Banks RE, Dunn MJ, Forbes MA, Stanley A, Pappin D, Naven T, Gough M, Harnden P, Selby PJ; (1999) 'The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomics analysis: Preliminary findings'. Electrophoresis, 20 :689-700. [Details]
Sutton CW, Pemberton KS, Cottrell JS, Corbett JM, Wheeler CH, Dunn MJ and Pappin DJ; (1995) 'Identification of myocardial proteins from two-dimensional gels by peptide mass fingerprinting'. Electrophoresis, 16 :308-316. [Details]
Dunn MJ, Crisp S, Rose ML, Taylor PM and Yacoub MH; (1992) 'Anti-endothelial antibodies and coronary artery disease after cardiac transplantation'. The Lancet, 339 :1566-1570. [Details]

Other Journals

Zhou, S., Mann, C.J., Dunn, M.J., Preedy, V.R., Emery, P.; (2006) 'Measurement of specific radioactivity in proteins separated by two-dimensional gel electrophoresis' Electrophoresis . [Details]
Dunn, M.J.; (2006) 'PROTEOMICS - Continued growth and comprehensive coverage' Proteomics . [Details]
                                                                                           

Research

Research Interests

The aim of our research is to identify and implement proteomic technologies and then to apply them to a variety of biomedical research programmes in collaboration with other groups both within the Conway, in other Departments of UCD and other laboratories in Ireland and worldwide. My own research programme is focused in three major areas of biomedicine: (1) cardiovascular proteomics, (2) transplantation proteomics, and (3) neuroproteomics. The overall aim of these studies is to further our understanding of the molecular basis of biological processes in health and disease and to identify new biomarkers that can be exploited as diagnostic/prognostic reagents and/or as therapeutic targets.


FUNDING:
- The Wellcome Trust. Behavioural and sub-cellular dissection of non-rod, non-cone ocular photoreceptors in mice and man (P.I. Professor Russell Foster, Imperial College London, UK) £1,442,656. 2003-2008
- The Wellcome Trust Redox signalling and ischaemic preconditioning: A potential role for protein S-thiolation (P.I. Dr Philip Eaton, King's College London, UK) £175,699. 2003-2006
- British Heart Foundation Role of endothelial cells in graft vasculopathy following cardiac transplantation (P.I. Professor Marlene Rose, Imperial College London, UK) £547,973. 2002-2007
- Science Foundation Ireland (PI David Cotter, RCSI) The investigation of the COMT KO mouse following exposure to cannabis during adolescence: a model for environment interaction and increased vulnerability to schizophrenia
€156,000. (2005-2007)
- Science Foundation Ireland Research Professorship in Biomedical Proteomics: Funding to support 5-year research programme. €3,115,54. (2004-2009)
- Science Foundation Ireland Research Professorship in Biomedical Proteomics, Supplementary Equipment Grant €336,396
     

Collaborators

Internal Collaborators

Professor Stephen Pennington, UCD School of Medicine & Medical Science. Collaborations in development of new and improved proteomic technologies. Collaborations in wide variety of proteomic projects with investigators in Conway and UCD.

Dr Keith Murphy, UCD School of Biomolecular & Biomedical Science. Proteomic profiling of memory consolidation-associated synaptic plasticity following passive avoidance and water maze paradigms

Dr Seamas Donnelly, UCD School of Medicine & Medical Science. Proteomic profiling of bronchoalveolar lavage fluid for the identification of biomarkers of lung disease. The current work is focussed on sarcoidosis.

Dr William Watson, UCD School of Medicine & Medical Science. Proteomic investigations of the role of neutrophils in rejection following cardiac transplantation.

Dr William Watson, UCD School of Medicine & Medical Science. Proteomic profiling of serum and urine for the identification of biomarkers in prostate cancer.

Dr Rosemary Clyne, UCD School of Biomolecular & Biomedical Science. Proteomic investigations of the role of the yeast polo-line kinase CDC5 in meiosis.


Professor Des Higgins, UCD School of Medicine & Medical Science. Development of new bioinformatics and statistical tools for the analysis of proteomics data.

Dr Gerard Cagney, UCD School of Biomolecular & Biomedical Science. Development of new methods and bioinformatic tools for proteomic analysis and data analysis.

Professor Cliona O'Farrelly, UCD School of Medicine & Medical Science/ St. Vincent's University Hospital. Proteomic analysis of the cellular and molecular mechanisms involved in maintaining local immunological homeostasis in human gut, liver and uterus.

Dr William Gallagher UCD School of Biomolecular & Biomedical Science. Biomarker discovery in disease using both gel-based and SELDI-MS proteomics platforms.

Dr Dolores Cahill, UCD School of Medicine & Medical Science. Analysis of antibody responses following cardiac transplantation using protein array technology.

Professor Helen Colhoun, UCD School of Medicine & Medical Science. Proteomic analysis of protein expression in heart disease and failure associated with diabetes.

Dr Jarlath Nally, Agriculture, Food Science & Veterinary Medicine/ Veterinary Science Centre. Proteomics investigations of Leptospirosis.


Current Research Group -
Dr Pamela Donoghue pamela.donoghue@ucd.ie  Post-Doc


Dr Ciara McManus ciara.mcmanus@ucd.ie Post-Doc


Ms Kyla Pennington (from 1st April 2006) Post-Doc
Mr Kasper Pedersen kasper.pedersen@ucd.ie  Research Assistant



External Collaborators

Professor Marlene Rose (Imperial College London)

Dr David Cotter, Royal College of Surgeons in Ireland.

I have extensive existing collaborations with other investigators at other institutions in Ireland, the UK and Worldwide. I am internationally recognised as an expert in the application of proteomic technologies in the area of biomedicine. I therefore have ready access to groups working in various relevant areas worldwide.