Researchers at UCD


Eoin O'Cearbhaill

Lecturer In Bioengineering

School of Mechanical & Materials Engineering
School of Mechanical & Materials Eng
Engineering Building
Belfield Dublin 4

Tel: +353-1-7161715


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Dr. Eoin O'Cearbhaill, BE, PhD, is a Lecturer/ Assistant Professor in Bioengineering at the UCD School of Mechanical & Materials Engineering. Prior to joining UCD, Dr. O'Cearbhaill was a Postdoctoral Fellow at Harvard Medical School (Harvard-MIT Health Sciences & Technology Division; Dept. of Medicine, Brigham & Women's Hospital), where his research focused on the conception and development of medical devices and the delivery of next generation therapeutics, in the laboratory of Prof. Jeffrey Karp. Based on his development of a mechanical clutch needle, designed to prevent through-puncture injuries, Dr O'Cearbhaill was awarded 1st prize at the MIT Sloan BioInnovations 2012 conference. He was also part of the team that received the Institution of Chemical Engineers' Innovative Product of the Year Award 2013 for their work on developing a bio-inspired microneedle adhesive.  
Dr O'Cearbhaill obtained his BE (Biomedical) and PhD from NUI-Galway. His doctorate focused on applying mechanical stimulation to MSCs for vascular tissue engineering applications. Subsequently, he worked for Veryan Medical, before joining Creganna-Tactx, where he worked in both manufacturing and design service roles, helping to establish their Specialty Needles Division in Marlborough, MA.
Dr O'Cearbhaill's interests include:
3D Printing of Medical Devices; Medical Device Innovation, Design and Commercialisation, including minimally invasive devices and delivery systems
Cell Biomechanics, Bioreactor Design & Tissue Engineering 


Honours and Awards

Year: 2012.
Title: Bioinnovations Best Presentation
Year: 2013.
Title: IChemE Innovative Product of the Year Award


Year 2008 Institution: NUI Galway, IRL
Qualification: PhD Subject: Biomedical Engineering
Year 2003 Institution: NUI Galway, IRL
Qualification: BE Subject: Biomedical Engineering



Peer Reviewed Journals

Feins, Eric N,Lee, Yuhan,Oâ¿¿Cearbhaill, Eoin D,Vasilyev, Nikolay V,Shimada, Shogo,Friehs, Ingeborg,Perrin, Douglas,Hammer, Peter E,Yamauchi, Haruo,Marx, Gerald (2017) 'A growth-accommodating implant for paediatric applications'. Nature Biomedical Engineering, 1 (10):818. [Details]
Kim, Bongsoo,Seong, Keum-Yong,You, Insang,Selvaraj, Veerapandian,Yim, Sang-Gu,Oâ¿¿Cearbhaill, Eoin D,Jeong, Unyong,Yang, Seung Yun (2017) 'Touch-Actuated Transdermal Delivery Patch for Quantitative Skin Permeation Control'. Sensors and Actuators B: Chemical, . [Details]
Seong KY, Seo MS;Hwang DY;O'Cearbhaill ED;Sreenan S;Karp JM;Yang SY (2017) 'A self-adherent, bullet-shaped microneedle patch for controlled transdermal delivery of insulin'. Journal of controlled release : official journal of the Controlled Release Society, . [DOI] [Details]
Meagher, P., O'Cearbhaill, E.D., Byrne, J.H., Browne, D.J. (2016) 'Bulk metallic glasses for implantable medical devices and surgical tools'. Advanced Materials, published online . [DOI] Link to full text [Details]
Cahill, Ellen Mary and O'Cearbhaill, Eoin D (2015) 'Towards Biofunctional Microneedles for Stimulus Responsive Drug Delivery'. Bioconjugate chemistry, . Link to full text [Details]
Zhang, Hong and Zhao, Tianyu and Duffy, Patrick and Dong, Yixiao and Annaidh, Aisling N\'\i and O'Cearbhaill, Eoin and Wang, Wenxin (2015) 'Hydrolytically Degradable Hyperbranched PEG-Polyester Adhesive with Low Swelling and Robust Mechanical Properties'. Advanced healthcare materials, 4 (15):2260-2268. [Details]
Roche, Ellen T,Fabozzo, Assunta,Lee, Yuhan,Polygerinos, Panagiotis,Friehs, Ingeborg,Schuster, Lucia,Whyte, William,Berazaluce, Alejandra Maria Casar,Bueno, Alejandra,Lang, Nora (2015) 'A light-reflecting balloon catheter for atraumatic tissue defect repair'. Science Translational Medicine, 7 (306). [Details]
Zhang, Hong and Zhao, Tianyu and Newland, Ben and Duffy, Patrick and Annaidh, Aisling N\'\i and O'Cearbhaill, Eoin D and Wang, Wenxin (2015) 'On-demand and negative-thermo-swelling tissue adhesive based on highly branched ambivalent PEG--catechol copolymers'. Journal of Materials Chemistry B, 3 (31):6420-6428. [Details]
O'Cearbhaill, Eoin D and Ng, Kelvin S and Karp, Jeffrey M (2014) 'Emerging Medical Devices for Minimally Invasive Cell Therapy'. Mayo Clinic Proceedings, 89 (2):259-273. [Details]
Oâ¿¿Brien, Barry and Oâ¿¿Cearbhaill, Eoin and Bruzzi, Mark (2014) 'A Stent with Customizable Length for Treatment of Critical Limb Ischemia: Clinical Need, Device Development and Pre-clinical Testing'. Cardiovascular Engineering and Technology, 5 (4):317-333. [Details]
Pereira MJ, Lang N, Lee Y, Friehs I, Vasilyev NV, Feins EN, Ablasser K, O'Cearbhaill ED, Xu C, Fabozzo A, Padera R, Wasserman S, Freudenthal F, Ferreira LS, Langer R, Karp JM, del Nido PJ (2014) 'A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects'. Science Translational Medicine, 6 (218). [DOI] [Details]
Yang, Seung Yun and O'Cearbhaill, Eoin D and Sisk, Geoffroy C and Park, Kyeng Min and Cho, Woo Kyung and Villiger, Martin and Bouma, Brett E and Pomahac, Bohdan and Karp, Jeffrey M (2013) 'A bio-inspired swellable microneedle adhesive for mechanical interlocking with tissue'. Nature communications, 4 :1702. [Details]
Mooney, Emma and Mackle, Joseph N and Blond, David J-P and O'Cearbhaill, Eoin and Shaw, Georgina and Blau, Werner J and Barry, Frank P and Barron, Valerie and Murphy, J Mary (2012) 'The electrical stimulation of carbon nanotubes to provide a cardiomimetic cue to MSCs'. Biomaterials, 33 (26):6132-6139. [Details]
Lang, Nora and Nunes Pereira, Maria and Friehs, Ingeborg and Vasilyev, Nikolay and Ablasser, Klemens and O'Cearbhaill, Eoin and Xu, Chenjie and Yamauchi, Haruo and Hammer, Peter and Wasserman, Steve and others (2012) 'A Biocompatible Light-Activated Adhesive for Intra-and Extracardiac Applications in Acquired and Congenital Heart Disease'. Circulation, 126 (21 Supplement):A19644. [Details]
Xu, Chenjie and Poh, Yuk Kee C and Roes, Isaac and O'Cearbhaill, Eoin D and Matthiesen, Mads Emil and Mu, Luye and Yang, Seung Yun and Miranda-Nieves, David and Irimia, Daniel and Karp, Jeffrey M (2012) 'A portable chemotaxis platform for short and long term analysis'. PloS one, 7 (9). [Details]
Oâ¿¿Cearbhaill, Eoin D and Murphy, Mary and Barry, Frank and McHugh, Peter E and Barron, Valerie (2010) 'Behavior of human mesenchymal stem cells in fibrin-based vascular tissue engineering constructs'. Annals of biomedical engineering, 38 (3):649-657. [Details]
Punchard, Marie A and Oâ¿¿Cearbhaill, Eoin D and Mackle, Joseph N and McHugh, Peter E and Smith, Terry J and Stenson-Cox, Catherine and Barron, Valerie (2009) 'Evaluation of human endothelial cells post stent deployment in a cardiovascular simulator in vitro'. Annals of biomedical engineering, 37 (7):1322-1330. [Details]
O'Cearbhaill, Eoin D and Punchard, Marie A and Murphy, Mary and Barry, Frank P and McHugh, Peter E and Barron, Valerie (2008) 'Response of mesenchymal stem cells to the biomechanical environment of the endothelium on a flexible tubular silicone substrate'. Biomaterials, 29 (11):1610-1619. [Details]
Crouchley, Claire M and Barron, Valerie and Punchard, Marie and O'Cearbhaill, Eoin and Smith, Terry (2008) 'Development of a co-culture system for tissue engineered vascular grafts'. Bio-medical materials and engineering, 18 (4-5):291. [Details]
Punchard, MA and Stenson-Cox, C and Oâ¿¿cearbhaill, ED and Lyons, E and Gundy, S and Murphy, L and Pandit, A and McHugh, PE and Barron, V (2007) 'Endothelial cell response to biomechanical forces under simulated vascular loading conditions'. Journal of biomechanics, 40 (14):3146-3154. [Details]
McGarry, JP and Oâ¿¿Donnell, BP and McHugh, PE and Oâ¿¿Cearbhaill, E and McMeeking, RM (2007) 'Computational Examination of the Effect of Material Inhomogeneity on the Necking of Stent Struts Under Tensile Loading'. Journal of Applied Mechanics, 74 :978. [Details]
O'cearbhaill, ED and Barron, V and McHugh, PE (2006) 'Characterisation of a collagen membrane for its potential use in cardiovascular tissue engineering applications'. Journal of Materials Science: Materials in Medicine, 17 (3):195-201. [Details]

Other Journals

Hannah Craddock, James Jones, Eoin O'Cearbhaill (2015) 'DEVELOPING PNEUMATIC MUSCLES AND A CONTROL SYSTEM TO OPERATE THEIR ACTUATION USING THE SOFT ROBOTICS TOOLKIT' Irish Journal of Medical Science . [Details]

Conference Publications

Krieger, K., Lowery, M.M., O¿Cearbhaill, E.D. (2016) Development of flexible microneedle electrodes for recording of surface EMG Proc. International Society of Electrophysiology and Kinesiology Congress [Details]
Yang, SY and O'Cearbhaill, E and Ong, JF and Pomahac, B and Karp, JM (2015) A Bio-Inspired Swellable Microneedle Adhesive for Mechanical Interlocking with Tissue BRITISH JOURNAL OF SURGERY , pp.115-115 [Details]
Yang, SY,O'Cearbhaill, E,Ong, JF,Pomahac, B,Karp, JM (2015) A Bio-Inspired Swellable Microneedle Adhesive for Mechanical Interlocking with Tissue , pp.115-115 [Details]


Research Interests

  • Medical Devices: Microneedles, Stents, Access devices, Specialty Needles, Catheter based delivery systems, Cardiac patch and stem cell delivery, Thrombectomy devices, Cell encapsulation implantable devices, Tissue adhesives; 3D Printing of medical devices and test models; device-tissue interactions & biomechanics

Research Projects

Sponsor : University College Dublin (UCD)
Title : Next Generation 3D-Printing and Advanced Manufacturing of Medical Devices
Start Date / End Date : 01-APR-14 / 30-SEP-15
Sponsor : University College Dublin (UCD)
Title : Development and Participation in the Horizon 2020 DRIVE Islet Transplantation Consortium
Start Date / End Date : 01-APR-14 / 30-SEP-15
Sponsor : Enterprise Ireland (EI)
Title : Innovation Voucher No: IV-2014-1164 Orthotics Solutions
Start Date / End Date : 06-MAR-14 / 06-MAR-15
Sponsor : University of Notre Dame
Title : Naughton Graduate Fellowship Program
Start Date / End Date : 01-SEP-14 / 31-AUG-18
Sponsor : HORIZON 2020
Title : Diabetes Reversing Implants with enhanced Viability and long-term Efficacy (DRIVE)
Start Date / End Date : 01-JUN-15 / 31-MAY-19
Sponsor : Enterprise Ireland (EI)
Title : Porous Medical Devices for the next generation therapeutic delivery
Start Date / End Date : 28-OCT-14 / 28-JUL-15
Sponsor : Health Research Board (HRB)
Title : Developing pneumatic muscles for integration with prosthetics using the soft robotics toolkit
Start Date / End Date : 02-JUN-15 / 11-SEP-15
Sponsor : Irish Research Council (IRC)
Title : Development of Flexible Microneedle Electrodes as Wearable Sensors for Long-term evaluation of Dynamic Muscle Performance
Start Date / End Date : 01-OCT-15 / 30-SEP-19
Sponsor : HORIZON 2020
Title : MICROPOrous Devices for next-generation therapeutic delivery (Micropod)
Start Date / End Date : 13-APR-15 / 12-APR-17
Sponsor : Gecko Biomedical
Title : Trial research
Start Date / End Date : 06-OCT-15 / 29-FEB-16
Sponsor : Enterprise Ireland (EI)
Title : Testing of Theya Fabric
Start Date / End Date : 12-OCT-15 / 30-APR-16
Sponsor : University College Dublin (UCD)
Title : Seed Funding for Microneedle 2016 Conference
Start Date / End Date : 01-APR-16 / 30-SEP-17
Sponsor : University College Dublin (UCD)
Title : EOC Personal Research Acc
Start Date / End Date : 28-JAN-16 / 01-JAN-26
Sponsor : Health Research Board (HRB)
Title : Development of Durable User-Specific 3D Printed Orthotics
Start Date / End Date : 06-JUN-16 / 16-SEP-16


Teaching Philosophy


Enhancement of Teaching

Review and Enhancement of Curriculum

Developing as a Teacher

Innovation & Leadership