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Researchers at UCD

Christopher McGuigan

Clinical Lecturer

School of Medicine

Tel:
Email: c.mcguigan@ucd.ie

Biography

I currently supervise a Biogen Idec sponsored Newman Fellow who is completing a PhD study on clinical and epidemiological aspects of Multiple Sclerosis in Ireland. In October 2014 a Neuroscience BSc student commenced an undergraduate thesis on Natlizumab and Alemtuzumab for MultipleSclerosis under my supervision. I have commenced an investigator led trial on the use of prolonged release Fampridine for upper limb function in patients with progressive multiple sclerosis and was appointed national lead on clinical trials for new treatments for spasticity, relapsing remitting and secondary progressive MS.

 

Member of SVUH Neurology Research Group

Publications

 

Book Chapters

O'Donnachda, S; McGuigan, C (2015) 'The nature of anxiety in people with MS' In: Langdon, D; Pia Amato, M (eds). Multiple Sclerosis: The Invisible Impacts. Milan: Springer-Verlag. [Details]
O'Donnachda, S; McGuigan, C (2015) 'Measurement and treatment of anxiety in people with MS' In: Langdon, D; Pia Amato, M (eds). Multiple Sclerosis: The Invisible Impacts. Milan: Springer-Verlag. [Details]
 

Peer Reviewed Journals

McNicholas N, McGuigan C (2016) 'A useful annual review of cognition in relapsing MS is beyond most neurologists - YES'. Multiple sclerosis (Houndmills, Basingstoke, England), 22 (6):726-728. [DOI] [Details]
Elamin M, Lonergan R;Killeen RP;O'Riordan S;Tubridy N;McGuigan C (2015) 'Posterior cortical and white matter changes on MRI in anti-AMPA receptor antibody encephalitis'. Neurology: neuroimmunology & neuroinflammation, 2 (4). [DOI] [Details]
Lynch DS, Jaunmuktane Z;Sheerin UM;Phadke R;Brandner S;Milonas I;Dean A;Bajaj N;McNicholas N;Costello D;Cronin S;McGuigan C;Rossor M;Fox N;Murphy E;Chataway J;Houlden H (2015) 'Hereditary leukoencephalopathy with axonal spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an adult onset leukodystrophy series'. Journal of Neurology, Neurosurgery and Psychiatry, . [DOI] [Details]
O'Connell K, Kelly SB;Fogarty E;Duggan M;Buckley L;Hutchinson M;McGuigan C;Tubridy N (2015) 'Economic costs associated with an MS relapse'. Multiple Sclerosis and Related Disorders, 3 (6):678-683. [DOI] [Details]
Fogarty E, Walsh C;McGuigan C;Tubridy N;Barry M (2014) 'Direct and indirect economic consequences of multiple sclerosis in Ireland'. Applied Health Economics and Health Policy, 12 (6):635-645. [DOI] [Details]
O'Connell K, Kelly S, Kinsella K, Jordan S, Kenny O, Murphy D, Heffernan E, O'Laoide R, O'Shea D, McKenna C, Cassidy L, Fletcher J, Walsh C, Brady J, McGuigan C, Tubridy N, Hutchinson M (2013) 'Dose-related effects of vitamin D on immune responses in patients with clinically isolated syndrome and healthy control participants: study protocol for an exploratory randomized double- blind placebo-controlled trial'. Trials, 14 . [DOI] [Details]
Fogarty E, Walsh C;Adams R;McGuigan C;Barry M;Tubridy N (2013) 'Relating health-related Quality of Life to disability progression in multiple sclerosis, using the 5-level EQ-5D'. Multiple Sclerosis, 19 (9):1190-1196. [DOI] [Details]
McGuigan C (2013) 'Evoked potentials are of little use in the diagnosis or monitoring of MS: yes'. Multiple Sclerosis, 19 (14):1820-1821. [DOI] [Details]
ÿ Donnchadha S, Burke T, Bramham J, O'Brien MC, Whelan R, Reilly R, Kiiski H, Lonergan R, Kinsella K, Kelly S, McGuigan C, Hutchinson M, Tubridy N (2013) 'Symptom overlap in anxiety and multiple sclerosis'. Multiple Sclerosis, 19 (10):1349-1354. [DOI] [Details]
Kelly S, Kinsella K, Duggan M, Tubridy N, McGuigan C, Hutchinson M (2012) 'A proposed modification to the McDonald 2010 criteria for the diagnosis of primary progressive multiple sclerosis'. Multiple Sclerosis, . [DOI] [Details]
Mullane D, Williams L;Merwick A;Tobin WO;McGuigan C (2012) 'Drug induced aseptic meningitis caused by intravenous immunoglobulin therapy'. Irish Medical Journal, 105 (6):182-183. [Details]
Williams L, O'Riordan S, McGuigan C, Hutchinson M, Tubridy N (2012) 'A web-based electronic neurology referral system: a solution for an overburdened healthcare system?'. Irish Medical Journal, 105 (9):301-303. [Details]
Kelly SB, Chaila E, Kinsella K, Duggan M, McGuigan C, Tubridy N, Hutchinson M (2011) 'Multiple sclerosis, from referral to confirmed diagnosis: an audit of clinical practice'. Multiple Sclerosis, 17 (8):1017-1021. [DOI] [Details]
Costelloe L, O'Rourke K, McGuigan C, Walsh C, Tubridy N, Hutchinson M (2008) 'The longitudinal relationship between the patient-reported Multiple Sclerosis Impact Scale and the clinician-assessed Multiple Sclerosis Functional Composite'. Multiple Sclerosis, 14 (2):255-258. [DOI] [Details]
Costelloe L, O'Rourke K, Kearney H, McGuigan C, Gribbin L, Duggan M, Daly L, Tubridy N, Hutchinson M (2007) 'The patient knows best: significant change in the physical component of the Multiple Sclerosis Impact Scale (MSIS-29 physical)'. Journal of Neurology, Neurosurgery and Psychiatry, 78 (8):841-844. [DOI] [Details]
Dunne C, McGuigan C, Crowley J, Hagan R, Rooney G, Kelleher J, Hutchinson M, Lawlor E (2006) 'Human leucocyte antigen class II polymorphism in Irish patients with multiple sclerosis'. Tissue Antigens, 68 (3):257-262. [DOI] [Details]
McGuigan C, Hutchinson M (2006) 'Unrecognised symptoms of depression in a community-based population with multiple sclerosis'. Neurology, 253 (2):219-223. [DOI] [Details]
McGuigan C, Dunne C, Crowley J, Hagan R, Rooney G, Lawlor E, Hutchinson M (2005) 'Population frequency of HLA haplotypes contributes to the prevalence difference of multiple sclerosis in Ireland'. Neurology, 252 (10):1245-1248. [DOI] [Details]

Other Journals

Lewis, JB; Merwick, A; Laoide, RO; O'Hare, A; McGuigan, C (2013) 'Therapeutic Decision Making in Acute Stroke due to Carotid Artery Dissection: A Potential Role for Percutaneous Vascular Intervention following Intravenous Thrombolysis' Case Reports in Vascular Medicine . [Details]

Conference Publications

Ó Donnchadha, S., Burke, T., Bramham, J., O'Brien, M.C., Whelan, R., Reilly, R., Lonergan, R., Kinsella, K., Kiiski, H., McGuigan, C., Hutchinson, M. & Tubridy, N. (2012) Symptom overlap in anxiety and multiple sclerosis: on the need for caution European Committee for Treatment and Research in Multiple Sclerosis Lyon, France, [Details]
Ó Donnchadha, S., Burke, T., Bramham, J., O'Brien, M.C., Whelan, R., Reilly, R., Lonergan, R., Kinsella, K., Kiiski, H., McGuigan, C., Hutchinson, M. & Tubridy, N. (2012) Usefulness of the Beck Anxiety Inventory (BAI) for the assessment of anxiety in multiple sclerosis 48th Meeting Irish Neurological Association Western Gateway Building, University College Cork, , 10-MAY-12 - 11-MAY-12 [Details]
Ó Donnchadha S., Bramham J., Burke T., O¿Brien M.C., Whelan R., Reilly R., Lonergan R., Kinsella K., Kiiski H., McGuigan C., Hutchinson M., & Tubridy N. ; (2011) A longitudinal study of processing speed and working memory in multiple sclerosis as measured by the Paced Auditory Serial Addition Test (PASAT) Irish Neurological Association Meeting [Details]
                       

Abstract

McEneaney, F,Kelly, S,Jackson, J,Hutchinson, M,Tubridy, N,McGuigan, C (2012) Unmatched CSF oligoclonal bands: can we differentiate between demyelinating disorders and other causes?. Abstract [Details]
Kinsella, K,Kelly, SB,DeGascun, CF,Carr, M,Duggan, M,Hutchinson, M,Tubridy, N,McGuigan, C (2012) THE SENSITIVITY OF JC VIRUS DNA DETECTION VS JC VIRUS ANTIBODY TESTING IN A NATALIZUMAB-TREATED GROUP OF RELAPSING MS PATIENTS. Abstract [DOI] [Details]
                                                               

Research

 

Research Projects

Sponsor : University College Dublin Foundation Ltd.
Title : Establishing the incidence of multiple sclerosis across the island of Ireland and examining the role of potential aetiological factors.
Start Date / End Date : 01-JUL-12 / 30-JUN-14
Sponsor : University College Dublin (UCD)
Title : Neurology Research Nurses
Start Date / End Date : 01-JUN-13 / 31-JAN-18
Sponsor : University College Dublin Foundation Ltd.
Title : Research activities of Dr Chris McGuigan in the UCD School of Medicine and Medical Science: Establishing a case-control study based on newly diagnosed multiple sclerosis patients in St. Vincent¿s University Hospital to assess clinical and cognitive f
Start Date / End Date : 01-MAR-15 / 05-JUL-18