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Researchers at UCD

researcher

Jack Lambert

Consultant/Senior Lecturer

School Of Medicine
Mater Hospital
Eccles Street
Dublin 7

Tel:
Email: jlambert@mater.ie

Biography

Current research focused on infections in pregnancy and treatment of HIV and Hepatitis C. Dr Lambert has successfully developed a database at the Rotunda and Mater Hospitals to monitor pregnant women with various infectious diseases, and also monitoring HIV drug levels in HIV positive pregnant women in receipt of HIV therapy. Active in Hepatitis C treatment and also developing national policies and strategies Dr Lambert is the recipient of a 228K two year grant from VIIV Access and Government Affairs department, to develop a paediatric AIDS database in two clinics in Eastern Cape South Africa. This database captures information on 2500 children, approximately 2000 of whom are on HIV treatment and captures important safety and clinical data on these children. Currently Dr Lambert has received further funding of 200K to develop this database in 4 countries: South Africa, Kenya, Swaziland and Zambia.

Dr Lambert¿s is currently developing research into international adolescent HIV. He is leading a multi country study including sites in Dublin, London, Bucharest Romania, Chiang Rai Thailand, Rio de Janeiro Brazil, Mona Jamaica, East London and Durban South Africa, He has been awarded a 237K grant from VIIV Access and Government Affairs for this project. His most recent grant for £150K focusses on Prevention of Mother to Child Transmission of HIV in South Africa.

Dr Lambert has also been awarded a 1.8 million euro three year grant to develop a community based intervention for HCV with the Horizons 2020 programme, with location in Dublin, London, Bucharest and Seville.

Professional

Honours and Awards

Year: 1984.
Title: Outstanding House Staff Teaching Award, Dept. of Pediatrics, Strong Memorial Hospital.

Associations

Association: American Society of Microbiology, Function/Role: Member
Association: Pediatric Infectious Disease Society, Function/Role: Member
Association: International Association of AIDS Physicians, Function/Role: Member
Association: British HIV Association, Function/Role: Member
Association: Childrens HIV Association of the UK and Ireland (CHIVA), Function/Role: Member
Association: Medical Society for Study of Venereal Diseases, Function/Role: Member
Association: Infectious Diseases Society of America, Function/Role: Member
Association: Royal College of Paediatrics and Child Health , Function/Role: Fellow
Association: Infectious Diseases Society of Ireland, Function/Role: Member
Association: Royal College of Physicians (UK), Function/Role: Fellow
     

Conference Contributions

Monteith, C; Eogan, M; Cooley, S; Lambert, J; Kelleher, B; Ni Ainle, F (2013) Hepatitis C virus associated immune thrombocytopenia in pregnancy: pregnancy management and morbidity. [Poster Presentation], British Maternal and Foetal Medicine Society Conference, Dublin , 25-APR-13 - 26-APR-13.
McCombe, G., Henihan, A.M., Klimas, J., Swan, D., Leahy, D., Anderson, R., Bury, G., Dunne, C., Keenan, E., Lambert, J., Meagher, D., O¿Gorman, C., O'Toole, T., Saunders, J., Smyth, B.P., Kaner, E., Cullen, W. (2015) Enhancing alcohol screening and brief intervention among people receiving opioid agonist treatment: Qualitative study in primary care. Addiction Health Services Research, .
McCombe G., Almaazmi B, Lambert J.S., Avramovic G., Murphy C., O'Connor M., Perry N., Cullen W. (2017) Integrating Primary and Secondary Care to Optimise Hepatitis C Treatment: Development and Evaluation of a Multidisciplinary Educational ¿Masterclass¿ Series. [Oral Presentation], AUDGPI Annual Scientific Meeting, Limerick, Ireland , 09-MAR-17 - 10-MAR-17.
O¿Connor E, Swan D, McCombe G, Murphy C, Lambert JS, Avramovic G, Cullen W (2017) Heplink: Integrating hepatitis C treatment in primary care. [Poster Presentation], Infectious Diseases Society of Ireland, Galway, Ireland , 04-MAY-17 - 06-MAY-17.
Crowley D, Cullen W, Keevans M, Kelly E, Lambert J S, McCombe G, McKiernan S, McHugh T, Miggin S, Murphy C, Van Hout M C (2017) Blocks and enablers to hepatitis C virus screening and treatment ¿ a prisoner¿s perspective. [Oral Presentation], 6th International Symposium on Hepatitis Care in Substance Users, New Jersey, USA , 06-SEP-17 - 08-SEP-17.
Waqas, S; O'Connor, M; Levey, C; Mallon, P; Sheehan, G; Patel, A; Avramovic, G; Lambert, JS (2015) Experience of dolutegravir (DTG) in HIV infected treatment naive patients from a tertiary care university hospital in Ireland. [Poster Presentation], EACS 2015, Barcelona , 21-OCT-15 - 24-OCT-15.
O'Halloran, JA; Herlihy, T; Macken, A; Rainford, L; Lambert, JS; Sheehan, GJ; Mahon, NG; Lawler, LP; Mallon, PWG (2015) Enhanced, not inhibited monocyte cholesterol efflux characterises untreated HIV. [Oral Presentation], CROI 2015, Seattle , 23-FEB-15 - 26-FEB-15.
Linder, V; Goldswain, C; Lambert, JS; Jackson, V; Boon, G; Harper, K; Carty, C (2015) Lamivudine monotherapy as a safe option for HIV infected children with challenging circumstances? New evidence from a large South African cohort. [Poster Presentation], CHIVA 2015, Leicester , 22-MAY-15 - 22-MAY-15.
A.G. Cotter, C. Rock, J. Brady, G. Sheehan, J. Lambert, C.A. Sabin, P.W.G. Mallon. ; (2012) Seasonal Changes in and Predictors of Parathyroid Hormone (PTH) Levels in HIV-1 Infected Subjects. [Poster Presentation], Submitted CROI 2012, Washington DC, US , 05-MAR-12 - 08-MAR-12.
A.G. Cotter, C. Rock, J. Brady, D. Healy, J. Lambert, G. Sheehan, C.A. Sabin, P.W.G. Mallon. ; (2011) Seasonal Changes in 25-OH Vitamin D and Parathyroid Hormone in HIV-infected Subjects. [Poster Presentation], EACS Conference, Belgrade, Serbia , 12-OCT-11 - 15-OCT-11.
E.R. Feeney, N. Mc Auley, J.A. O¿Halloran, C. Rock, J. Low, J.S. Lambert, G.J. Sheehan, C.S. Satchell, P.W.G. Mallon.; (2011) . The Differential Expression of Cholesterol Metabolism Genes in Monocytes from Treated and Untreated HIV-Infected Subjects Compared to HIV-Negative Controls Suggests Impairment in Reverse Cholesterol Transport and Intracellular Cholesterol Accumulation. [Poster Presentation], EACS Conference, Belgrade, Serbia , 12-OCT-11 - 15-OCT-11.
V. Jackson, W. Ferguson, M. Eogan, L. Else, S. Khoo, M. Brennan, C. Weldridge J. Lambert.; (2011) Transplacental Transfer of Atazanavir and Neonatal Hyperbilirubinaemia. [Poster Presentation], CHIVA Conference, Cardiff, UK , 16-MAY-11 - 20-MAY-11.
C. Rock, V. Jackson, V. Ciprike, M. Brennan, W Ferguson, M. Eogan, J. Lambert.; (2011) Antenatal Screening of Syphilis in Pregnant Women and their Partneirs- The Importance of Contact Tracing. [Poster Presentation], The 2011 Annual Scientific Meeting of the Infectious Diseases Society of Ireland (IDSI), Kildare Street, Dublin, Ireland , 07-JUN-11 - 08-JUN-11.
C. Boyle, A Wilson, G. Treacy, G. Sheehan, J. Lambert, C Meegan, PW.; (2011) Antiretroviral Regimen Complexity as a Predictor of Adherence. [Poster Presentation], The 2011 Annual Scientific Meeting of the Infectious Diseases Society of Ireland (IDSI), Kildare Street, Dublin, Ireland , 07-JUN-11 - 08-JUN-11.
C. Rock, P. Kyithar, V. Jackson, M. Brennan, M. Eogan, J. Edwards, A. Fleming, M. Byrne, J. Lambert.; (2011) Impaired Glucose metabolism in HIV-1 seropositive pregnant women: a prospective analysis. [Poster Presentation], The 2011 Annual Scientific Meeting of the Infectious Diseases Society of Ireland (IDSI), Kildare Street, Dublin, Ireland , 07-JUN-11 - 08-JUN-11.
J.S. Lambert, G. Avramovic, V. Jackson, M. Brennan, F.J. Campbell. ; (2011) Investigation into the Reasons for Maternal Default from HIV Care Post-partum. A 3 Year Retrospective Review. [Poster Presentation], EACS Conference, Belgrade, Serbia , 12-OCT-11 - 15-OCT-11.
W. Tinago, J. O¿Halloran, A. Macken, J. Lambert, G. Sheehan, P.W.G. Mallon. ; (2011) Protease Inhibitors Resistance after Unplanned Treatment Interruptions. [Poster Presentation], EACS Conference, Belgrade, Serbia , 12-OCT-11 - 15-OCT-11.
L.J. Else, V.Jackson, M. Brennan, J. Breiden, C. Weldridge, S. Coulter-Smith, D.J. Back, S.H. Khoo, J. Lambert.; (2010) Therapeutic drug monitoring of atazanavir in pregnancy. [Poster Presentation], Tenth International Congress on Drug Therapy in HIV Infection, Glasgow, UK , 07-NOV-10 - 11-NOV-10.
D. Swan, W. Cullen, S. Liddy, O. Carr, J. Flanagan, H. Irish, S. Keating, M. Keaveney, J. Lambert, J. Long, A. Mc. Cormick, S. McKiernan, J. Moloney, N. Perry.; (2010) Obstacles and facilitators of Hepatitis C testing and treatment among people who inject or have injected drugs: the views of service-providers. [Poster Presentation], Hepatitis Conference 2010, Dublin Castle, Ireland , 01-OCT-10 - 03-OCT-10.
A. Cotter, C.S. Satchell, J. O¿Halloran, E.Feeney, E. O¿Connor, G. Sheehan, J. Lambert, C. Sabin, P. Mallon. ; (2010) The protease inhibitor atazanavir and predictors of prolonged QT interval in HIV-1 Infected Patients. [Poster Presentation], Lipodystrophy 2010 Conference, London, UK , 17-NOV-10 - 17-NOV-10.
C. Sadlier, A. Brown, J. Lambert, G. Sheehan, P. Mallon. ; (2010) Seroprevalence of Schistosomiasis and Strongyloides Infection in Patients from Endemic Areas attending a European Infectious Diseases Clinic. [Poster Presentation], Helminth ICAAC 2010, Boston, US , 15-SEP-10 - 16-SEP-10.
1J.S. Lambert, L.J. Else, V. Jackson, L. Dickinson, D.J. Back, M. Brennan, C. Weldridge, S. Coulter-Smith, S. Gibbons, S.H. Khoo. ; (2010) The use of darunavir/ritonavir once daily regimen in two pregnant women. [Poster Presentation], Tenth International Congress on Drug Therapy in HIV Infection, Glasgow, UK , 07-NOV-10 - 11-NOV-10.
C. Boyle, A. Wilson, G. Treacy, G. Sheehan, J. Lambert, C. Meegan, P. Mallon.; (2010) Antiretroviral regimen complexity as a predictor of adherence. [Poster Presentation], Tenth International Congress on Drug Therapy in HIV Infection, Glasgow, UK , 07-NOV-10 - 11-NOV-10.
J. Lambert, L Else, V Jackson, J Breiden, S Gibbons, L Dickinson, D Back, M Brennan, C Weldridge, S Coulter Smith, S Khoo. ; (2010) The use of Darunavir/ritonavir once daily regimen in two pregnant women. [Poster Presentation], Submitted for IAS Vienna conference 2010, vienna , 18-JUL-10 - 23-JUL-10.
J. Lambert, M. Eogan, V. Jackson, M. Brennan,V Ciprike, J. Gleeson, K B Grundy, S. Coulter¿Smith, M. Cafferkey.; (2010) A 3-year Review of infections in pregnancy at a Busy Inner City Maternity Hospital. [Poster Presentation], BHIVA Conference, Manchester, UK , 20-APR-10 - 23-APR-10.
M. Geary, S. Coulter-Smith, M. Cafferkey, V. Jackson, M. Brennan, B. Kelleher, M. O Reilly, K.B Grundy, A. Jackson, J.S. Lambert. ; (2009) Universal Antenatal Screening For Hepatitis C At An Irish Maternity Hospital. [Poster Presentation], SMFM 29th Annual Meeting, San Diego , 26-JAN-09 - 31-JAN-09.
D. Swan, W. Cullen, J. Long, J. Flanagan, O. Carr, I. Helena, S. Keating, M. Keaveney, J.S. Lambert, A. Mc Cormick, J. Moloney, N. Perry. ; (2009) A qualitative exploration of coping strategies deployed by injecting drug users with Hepatitis C. [Poster Presentation], Hepatitis C 3rd International Conference, Dublin Castle, Ireland , 17-JUN-09 - 19-JUN-09.
J. Low, D. Crowley, M. Nicholls, W. Cullen, J. Flanagan, N. Glover, J. Lambert.; (2009) Treatment of Hepatitis C Infected Patients in a Community Based Drug Treatment Service in Partnership with Hospital Based Specialist Services. [Poster Presentation], Summer Student Research Elective 2009, UCD School of Medicine and Medical Science (SMMS), Dublin , 01-JUL-09 - 01-JUL-09.
E. Kent, R. Akaawi, V. Jackson, M. Brennan, S. Coulter-Smith, J.S. Lambert, M. Geary, F. D. Malone.; (2009) Clinical Risk Factors are not Predictive of Hepatitis C PCR Positivity. [Poster Presentation], SMFM 29th Annual Meeting, San Diego , 26-JAN-09 - 31-JAN-09.
Claudette Satchell, A Cotter, E O'Connor, A Peace, T Tedesco, A Clare, J Lambert, G Sheehan, D Kenny, and P Mallon. ; (2009) A Case Control Assessment of Platelet Function in HIV-1+ and HIV-1- Individuals. [Poster Presentation], 16th Conference on Retroviruses & Opportunistic Infections, Montreal, Canada , 08-FEB-09 - 11-FEB-09.
M. Brennan, M. Eogan, V. Jackson, J. Lambert, J. Gleeson, S. Coulter¿Smith, S. Devitt, M. Cafferkey.; (2009) A Review of a CMS Co-ordinated Dedicated ID Clinic at a Busy Inner City Maternity Hospital. [Poster Presentation], The INO Annual Midwifery Conference, Dublin , 15-OCT-09 - 15-OCT-09.
Lambert J; (2009) Scientific Committee Member. [Conference Organising Committee Member], - VI International Conference on HIV infection among women and children, Petropolis , 08-JUL-09 - 10-JUL-09.
V. Ciprike, V. Jackson, M. Cafferkey, S. Coulter-Smith, M. Brennan, K.B Grundy, M. Eogan, J.S. Lambert.; (2009) An Audit of Syphilis Serology in Pregnant Women Attending the Rotunda Hospital 2005-2008. [Poster Presentation], Irish Perinatal Society Annual Meeting, Carton House, Kildare, Ireland , 20-MAR-09 - 20-MAR-09.
L. Brennan, K. Grundy, M. Beckett, M. O Connell, A. Fitzgibbon, M. Brennan, J.S. Lambert, T. Clarke, M. Cafferkey. ; (2009) Stethoscopes: Potential Reservoirs For The Spread Of Nosocomial Infections. [Poster Presentation], The Joint Faculty of Paediatrics and Welsh Paediatric Society Meeting, Fota Island, Cork, Ireland , 14-MAY-09 - 16-MAY-09.
J.S. Lambert, M. Eogan, V. Jackson, M. Brennan, V. Ciprike, J. Gleeson, K.B. Grundy, S. Coulter-Smith, M. Cafferkey. ; (2009) A 2-year review of infections in pregnancy at a busy inner city maternity hospital. [Poster Presentation], The Infectious Diseases Society of Ireland Annual Scientific Meeting, Dublin , 11-JUN-09 - 12-JUN-09.
V. Ciprike, V. Jackson, M. Cafferkey, S. Coulter-Smith, M. Brennan, K.B Grundy, M. Eogan, J.S. Lambert. ; (2009) An Audit of Syphilis Serology in Pregnant Women Attending the Rotunda Hospital 2005-2008. [Poster Presentation], International Meeting of the Institute of Obstetricians & Gynaecologists, Royal College of Physicians, Dublin , 27-FEB-09 - 27-FEB-09.
J.S. Lambert, V. Jackson, M. Brennan, B. Kelleher, S. Coulter-Smith, M. O Reilly, M. Geary, K. B. Grundy, A. Jackson, M. Cafferkey. ; (2008) The Prevalence of Hepatitis C in Pregnancy: An Evaluation of Universal Antenatal Screening at an Irish Maternity Hospital. [Poster Presentation], 48th Annual Inter-science Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Washington, DC , 25-OCT-08 - 28-OCT-08.
J.S. Lambert, L. Else, V. Jackson, S. Gibbons, M. Brennan, J. Kieran, J. Breiden, S. Coulter-Smith, S. Khoo.; (2008) Therapeutic Drug Monitoring of Atazanavir in pregnancy. [Poster Presentation], The 9th International Congress on Drug Therapy in HIV Infection, Glasgow, Scotland , 09-NOV-08 - 13-NOV-08.
V. Jackson, L. Else, S. Khoo, S. Gibbons, M. Brennan, E. O Connor, N. Boyle, C. Fleming, S. Coulter-Smith, J.S. Lambert.; (2008) Therapeutic Drug Monitoring of new formulation Kaletra in pregnancy. [Chaired Session], The 9th International Congress on Drug Therapy in HIV Infection, Glasgow, Scotland , 09-NOV-08 - 13-NOV-08.
Ogunlewe, O. Coulter-Smith, M. Cafferkey, V. Jackson, M. Brennan, B. Kelleher, K.B Grundy, J.S. Lambert. ; (2008) The Prevalence Of Hepatitis B In Pregnant Women Attending The Rotunda Hospital 2006-07. [Poster Presentation], Junior Obstetric & Gynaecology Society Annual Scientific Meeting, Royal College of Physicians, Dublin , 28-NOV-08 - 28-NOV-08.
F. Olatunbosun, V. Jackson, J.S. Lambert, M. Brennan, M. Cafferkey, M. Geary, F. D. Malone, S. Coulter-Smith. ; (2008) Impact of viral infection and substance abuse in pregnancy on perinatal outcome. [Poster Presentation], Junior Obstetric & Gynaecology Society Annual Scientific Meeting, Royal College of Physicians, Dublin , 28-NOV-08 - 28-NOV-08.
Lambert J; (2008) The Third Decade and Beyond. [Chaired Session], International Conference on Hepatitis C, various , 01-MAR-08 - 01-NOV-11.
Howard R, Lambert JS; (2008) Hepatitis B vaccination uptake and series completion in an urban sexually transmitted infection clinic. [Poster Presentation (Refereed)], BASHH ASTDA Joint Meeting 2008, Brooklyn, New York City, USA , 07-MAY-08 - 10-MAY-08.
Wong V, Smith S, Lambert JS; (2008) Do we still need Intrapartum Zidovudine?. [Poster Presentation], Irish Perinatal Society Meeting 2008, Dublin Ireland , 11-APR-08 - 12-APR-08.
Cotter A, Brown A, Sheehan G, Lambert JS, Mallon P.; (2008) Patients with HIV and Hepatitis C co-infection experience less Atazanavir-induced hyperbilirubinaemia. [Poster Presentation (Refereed)], 14th Annual BHIVA Conference, Belfast, Northern Ireland , 23-APR-08 - 25-APR-08.
McMenamin M, Jackson A, Lambert JS, Coulter-Smith S, Jones L, McAuliffe F.; (2008) Vertical Transmission of Hepatitis C. [Chaired Session], American Society of Obstetrics/Gynaecology, Houston , 11-SEP-08 - 13-SEP-08.
112. Jackson V, Lambert JS, Brennan M, Kelleher B, Coulter-Smith S, O¿Reilly M, Geary M, Gurndy KB, Jackson A, Cafferkey M.; (2008) The Prevalence of Hepatitis C Among Pregnant Women Attending an Irish Maternity Hospital: An Evaluation of Universal Antenatal Screening. [Poster Presentation], Summer Scientific Meeting, Faculty of Public Medicine, Royal College of Physicians, Dublin, Ireland , 27-MAY-08 - 28-MAY-08.
Sukumaran V, McCoy K, Howard R, Lambert JS. ; (2007) Cervical cancer screening: a retrospective review of smear results in the setting of a sexual health clinic. [Published Abstract], BASHH Spring Meeting, Blackpool , 01-OCT-07.
Brennan M, Coulter-Smith S, Lambert JS, Cafferkey M.; (2007) The Midwife Coordinator: A Vital Role in the DOVE Clinic. [Poster Presentation (Refereed)], National HIV Nurses Association conference, London UK , 28-JUN-07 - 29-JUN-07.
Howard R, Lambert JS. ; (2007) Uptake of Hepatitis B Vaccination in an Infectious Diseases Clinic in Dublin. [Chaired Session], SSSTDI Meeting, Dublin , 28-MAR-07 - 28-MAR-07.
Kieran J, Cotter A, O¿Connor E, Brennan M, Khoo S Gibbons S, Lambert JS; (2007) Pharmacological Monitoring in Clinical Practice. [Poster Presentation (Refereed)], 11th European AIDS Conference/EACS, Madrid, Spain , 24-OCT-07 - 27-NOV-07.
Lambert JS, Gallagher D.; (2007) Abacavir Hypersensitivity and HLA-B*5701 Screening: Experience in an Inner City Cohort. [Poster Presentation (Refereed)], 13th Annual Conference of the British HIV Association (BHIVA) with the British Infection Society (BIS), Edinburgh International Conference Centre, Scotland , 29-MAR-07 - 01-APR-07.
Lambert, J.; (2006) STIs in Pregnancy. [Oral Presentation], Society for the Study of Sexually Transmitted Diseases in Ireland, Spring Meeting, Castleknock, Dublin 15 , 01-MAR-06 - 01-MAR-06.
Lambert JS, Sill AM, Machado ES, Watson D, Devico A.; (2006) High production of HIV suppressive chemokines correlates with favourable clinical parameters in HIV-infected children receiving antiretroviral therapy. [Oral Presentation], World AIDS Conference, Toronto, Canada , 01-JAN-06.
Lambert, J.; (2006) TB and HIV: from Africa to the EU. [Oral Presentation], TB - A Global Disease, International Approaches for control and prevention and a model programme for Ireland, World TB Day, Post Graduate Centre, Mater Misericordiae Hospital, Eccles St, Dublin 7 , 01-MAR-06.
Brannigan E, Chew N, Keogh M, Hannan M, Sheehan G, Lambert J; (2006) A North Dublin Inner City experience of HIV/Mycobacterial co-infection. [Poster Presentation (Refereed)], Glasgow HIV Conference 2006, Glasgow , 12-NOV-06 - 15-NOV-06.
100. Sill AM, Lambert JS, Machado ES, Tanuri A, Watson DC, Alfonso AO, da Cunha SC, Oliveira RH, Bowlsbey AL, Devico AL.; (2006) Higher chemokine secretion in HIV-infected Brazilian children is associated with higher CD4 and lower viral load. [Poster Presentation (Refereed)], Annual Meeting of the Institute of Human Virology, Baltimore, US , 17-NOV-06 - 17-NOV-06.
98. Caswell RJ, Doshi DS, Khoo SH, Gibbons S, Chaponda M, Poulton M, Welch J, McDonald C, Lambert J; (2006) Therapeutic Drug Monitoring (TDM): Is it of clinical utility in HIV positive pregnant women?. [Poster Presentation (Refereed)], Glasgow HIV Conference 2006, Glasgow , 12-NOV-06 - 16-NOV-06.
McDonald C, Lambert JS, Nayagam D, Welz T, Poulton M, Welch J.; (2006) Why are Children Still Being Infected with HIV?. [Oral Presentation], British HIV Association, 12th Annual Conference, Brighton, UK , 29-MAR-06 - 01-APR-06.
Chew N, Muldoon E, Sheehan G, Lambert JS, Powderly W.; (2006) Does Tenofovir Have Any Effect on Haemoglobin Levels?. [Chaired Session], Glasgow HIV Conference 2006, Glasgow , 12-NOV-06 - 15-NOV-06.
Machado E, Hofer C, Nogueira S, Costa T, Lambert JS.; (2005) Pregnancy outcome in HIV-1 infected women receiving combination therapy prior to conception. [Poster Presentation], CROI, Boston USA , 01-JAN-05.
McFarland E, Johnson D, Lambert JS et al.; (2005) Safety and Cell-mediated Immune Response to Prime-Boost Immunization with ALVAC HIV Vaccine in infants born to HIV infected Mothers (PACTG 326). [Oral Presentation], CROI, Boston USA , 01-JAN-05.
Machado ES, Lambert JS, Afonso AO et al.; (2004) Alternative, age-related routes of nelfinavir resistance in HIV type 1 infected children under highly active antiretroviral therapy. [Oral Presentation], XV International Conference on AIDS, Bangkok Thailand , 01-JAN-04.
Lambert JS, McLean KA, Mandalia S. et al.; (2004) Review of HSV simplex type 1 and 2 type specific serology requests performed at three GUM clinics. [Oral Presentation], BASSH Conference, Bath , 01-JAN-04.
Cunha DC Guimaraes MAA, Nogueira SA, Rodrigues R, Lambert JS. ; (2004) Co-infection of HTLV-1 and HIV in a cohort of pregnant women in the city of Rio de Janeiro, Brazil. [Oral Presentation], XV International Conference on AIDS, Bangkok Thailand , 01-JAN-04.
Afonso AO, Soares MA, Lambert JS, Cunha SM, Oliveira RH, Machado ES.; (2004) Early emergence of drug resistance mutations in HIV infected children starting dual and triple therapy. [Oral Presentation], XV International Conference on AIDS, Bangkok Thailand , 01-JAN-04.
Nogueira SA, Pinheiro T, Abreu TF, Machado ES, Lambert JS.; (2004) Successful prevention of mother to child transmission with HAART in a developing country. [Oral Presentation], XV International conference on AIDS, Bangkok Thailand , 01-JAN-04.
Machado ES, Lambert JS, Schrago C et al. ; (2004) Higher selective pressure on V3 crown of HIV-infected children with longer survival. [Oral Presentation], XV International Conference on AIDS,, Bangkok Thailand , 01-JAN-04.
Johnson D, McFarland E, Muresan P, Fenton T, Lambert JS, McNamara J, Hawkins E, Boquin P, Estep S, Read J, Gunurathan S; (2003) PACTG326: A Phase 1/II study of the Safety and Immunogenicity of an HIV-1 ALVAC Vaccine in Infants Born to HIV-Infected Mothers. [Non Refereed Paper/Abstract Presented at Conference], 10th Conference on Retroviruses and Opportunistic Infections, Boston, Massachusetts, USA , 10-FEB-03 - 14-FEB-03.
Watts DH, Lambert JS, Stiehm ER, Harris DR, Bethel J, Mofenson L, Mathieson B, Fowler MG, Nemo G.; (2003) Clinical, , Virologic, and Immunologic Changes after Delivery among Women Receiving Nucleoside Therapy during Pregnancy. [Oral Presentation], 10th Conference on Retroviruses and Opportunistic Infections, Boston, Massachusetts, USA , 10-FEB-03 - 14-FEB-03.
McFarland E, Johnson D, Fenton T, Muresan P, McNamara J, Hawkins E, Estep S, Read J, Gunurathan S, Lambert JS ; (2003) A Phase 1/II study of the Safety and Immunogenicity of an HIV-1 ALVAC Vaccine in Infants Born to HIV-Infected Mothers. [Oral Presentation], 10th Conference on Retroviruses and Opportunistic Infections, Boston, Massachusetts, USA , 10-FEB-03 - 14-FEB-03.
Nogueria S, Correa R, Holanda M, Cruz M & Lambert JS; (2002) Prevalencia de Strongyloides Stercoralis em Pacientes Infectados Pelo HTLV-1 Provenientes de uma Casuistica Hospitalar. [Non Refereed Paper/Abstract Presented at Conference], XXXVIII Congress de Soliedade Brasilkeira de Medicina Tropical, Rio de Janeiro , 01-FEB-02.
Machado E, Lambert JS, Afonso AO, Cunha SC, Caride E, Nogueira S, Oliveira RH, Watson DC, Sill AM, DeVico Al and Tanuri A.; (2002) Distribuicao dos Subtipos de HIV-1 em Criancas Soropositivas Acompasnhadas no Ippmg. [Non Refereed Paper/Abstract Presented at Conference], XXXVIII Congress de Soliedade Brasilkeira de Medicina Tropical, Rio De Janeiro , 01-FEB-02.
Elizabeth S Machado, Lambert JS, Watson DC, et al. ; (2002) Analise genotipica em criancas HIV-1 + em uso de terapia antiretroviral dupla ou tripla: resistencia ou baixa adesao. [Non Refereed Paper/Abstract Presented at Conference], IV Conferencia sobre Infeccao pelo HIV Em Mulchers E Criancas, * , 01-APR-02.
Noguira Susie, Barretto J, da Costa, Lambert JS, Dias Marcos. ; (2002) Estrategias Educacionais pra a capacitacao de professionals de saude da transmissio vertical do HIV. [Non Refereed Paper/Abstract Presented at Conference], IV Conferencia sobre Infeccao pelo HIV Em Mulchers E Criancas,, * , 01-APR-02.
Susie Nogueria, Elizabeth S Machado, Tomaz P da Costa, Maria Angelica Maan, Raimunda Rodrigues & Lambert JS.; (2002) Prevalencia de Co-infeccoes numa coorte de gestantes infectadas pelo HIV no Rio de Janeiro. [Non Refereed Paper/Abstract Presented at Conference], IV Conferencia sobre Infeccao pelo HIV Em Mulchers E Criancas, * , 01-APR-02.
Susie Nogueria, Elizabeth S Machado, Tomaz P da Costa, Thalita F Abreu, Ricardo Oliveira, Marcia Bondarowski, and Lambert JS. ; (2002) Evolocao do Uso de anti-retrovirais e Tipo de parto Num Programa de prevencao da transmissao vertical do HIV. [Non Refereed Paper/Abstract Presented at Conference], IV Conferencia sobre Infeccao pelo HIV Em Mulchers E Criancas, * , 01-APR-02.
Nogueria S A, Lambert JS. ; (2002) Changes over time in the use of antiretrovirals to prevent vertical transmission of HIV. [Refereed Abstracts], XIV AIDS Conference, Barcelona , 01-JAN-02.
Nogeria S, Machado E, Costa T, Abreu T, Taveraes M, Oliveria RH & Lambert JS.; (2002) Evolution of the use of antiretrovirals (ARV) to prevent HIV MTCT in Rio de Janeiro, Brazil. [Non Refereed Paper/Abstract Presented at Conference], XIV AIDS Conference, Barcelona , 01-JAN-02.
Nogueria S A, Lambert JS; (2002) Co-infection with Toxoplasma gondii in a cohort of HIV infected pregnant women. [Refereed Abstracts], XIV AIDS Conference, Barcelona , 01-JAN-02.
Beatriz A Carvalho, Lambert JS, Barbosa M, Ney A Grillo.; (2002) Funded by the Elizabeth GlaserPaediatric AIDS foundation. [Non Refereed Paper/Abstract Presented at Conference], IV Conferencia sobre Infeccao pelo HIV Em Mulchers E Criancas, * , 01-APR-02.
Susie Nogueria, Elizabeth S Machado, Tomaz P da Costa, Thalita F Abreu, and Lambert JS.; (2002) Infeccao pelo HIV em Adolescentes Gestantes: Mais um Problema A ser Enfrentado. [Non Refereed Paper/Abstract Presented at Conference], IV Conferencia sobre Infeccao pelo HIV Em Mulchers E Criancas, * , 01-APR-02.
Lambert JS.; (2002) Mitochondrial Toxicity and HIV Therapy. [Non Refereed Paper/Abstract Presented at Conference], IV Conferencia sobre Infeccao pelo HIV Em Mulchers E Criancas, * , 01-APR-02.

Committees

Committee : Scientific Committee Member- VI International Conference on HIV infection among women and children, Petropolis, July 8-10 2009
Committee : International Conference on Hepatitis C - The Third Decade and Beyond, Session Chair
Committee : Task Force Committee Hygiene/MRSA, Mater Misericordae University Hospital (MMUH).
Committee : Research Ethics (MMUH).
Committee : Biosafety Committee, University College Dublin (UCD).
Committee : School of Medical Science Clinical Curriculum Board (UCD)
Committee : National Aids Strategy Committee, Dept of Health and Children, Health Service Executive (HSE), Ireland.
Committee : Nasc-Care and Management Sub-committee, Dept of Health and Children, HSE, Ireland.
Committee : Health Information and Quality Authority (HIQA) HPV Vaccine Advisory Panel, Dublin, Ireland.
Committee : Drugs and Therapeutics Committee (MMUH).
Committee : Medical School Curriculum Committee, UCD
Committee : Dublin North Regional Strategy for the Control of Antimicrobial Resistance in Ireland (SARI)
Committee : Infection Control Committee, (MMUH)
Committee : Medical School Admission Committee, UCD
Committee : National Isolation Task Force (MMUH)
Committee : HSE National SARI Antimicrobial Stewardship Working Group
Committee : HSE IHR Implementation: Communicable Disease Subgroup
Committee : ITU Network for H1N1 Flu International
Committee : National Action Plan for Pandemic Influenza, Pandemic Influenza Emergency Management Committee, Rotunda Hospital, Ireland
Committee : National Standing Advisory committee for Blood Borne Viruses, Infectious Disease Society of Ireland.
Committee : International Health Regulations (IHR) Communicable Disease Sub-Group, HSE, Ireland.
Committee : Dublin North Regional SARI Infection Control Committee
Committee : Clinical Curriculum Board Member
Committee : Clinical 1 Board member
Committee : Graduate Entry to Medicine Stages 1 &2
Committee : National Standing Advisory Committee on the Prenvention of Blood Borne Viruses Diseases in the Health Care Setting.
Committee : HPSC Scientific Advisory Committee Emergency Management of Injuries Sub-Committee

Employment

Employer: Univ. of Rochester School of Medicine
Position: Instructor in Medicine and Pediatrics
Employer: Univ. of Rochester School of Medicine.
Position: Assistant Professor of Medicine & Pediatrics. Director of the AIDS
Employer: JHU School of Hygiene & Public Health, Baltimore, Maryland
Position: Assistant Professor International Health
Employer: JHU AIDS Vaccine Evaluation Unit (AVEU), Consortium of JHMI and Univ. of Maryland
Position: Clinical Director, Course Director, Division of Vaccine Science, Department of International Health, School of Hygiene and Public Health
Employer: Institute of Human Virology, University of Maryland
Position: Assistant Professor of Medicine and Pediatrics, Division of Clinical Research, Infectious Diseases and Peds Immunology
Employer: Great Ormond Street Children¿s Hospital, University College London UK
Position: Honorary Senior Lecturer and Locum Consultant,
Employer: Mater Misericordiae Hospital, Rotunda Hospital, University College Dublin
Position: Consultant in Medicine/GUM/Infectious Diseases and Senior Lecturer
     

Outreach Activities

2012-2013 East London - South Africa. Audit of HIV infected children Project
2005-2011 Baphumelele Project- Capetown, South Africa. Support for hospice programme, consultancy project.

2005-2011
CHIVA South Africa- Mentoring of doctors and nurses on ARV rollout for pregnant women and children with HIV.

Journals Edited

Journal Of Infectious Diseases: Reviewer.
Journal Of Pediatrics : Reviewer.
Pediatrics: Reviewer.
Clinical Immunology: Reviewer.
Aids Research And Human Retroviruses: Reviewer.
Journal Of Evaluation In Clinical Practice: Reviewer.
Archives Of Pediatrics & Adolescent Medicine: Reviewer.
Clinical And Diagnostic Laboratory Immunology: Reviewer.
Annals Of Internal Medicine: Reviewer.
International Journal Of Std And Aids: Reviewer.
Clinical Infectious Diseases: Reviewer.

Other Activities

PEER REVIEW WORK
Journal of Infectious Diseases
• Journal of Pediatrics
• Pediatrics
• Clinical Immunology
• AIDS Research
• Clinical Infectious Diseases
• Archives of Pediatrics and Adolescent Medicine
• Clinical and Diagnostic Laboratory Immunology
• Annals of Internal Medicine
• J. Acquired Immunodeficiency Syndrome
• J. Institute of Human Virology
• International J of STD and AIDS
Ad Hoc Review of Proposals:
• Pediatric AIDS Foundation--Grant Review
• NIDA Grant Review
• NIAID - AIDS Grant Review
Review of Publications:
• U.S.P. Drug Information Text
• American Hospital Formulary Drug Information

Publications

     

Peer Reviewed Journals

O'Higgins, A. C. and Jackson, V. and Lawless, M. and Le Blanc, D. and Connolly, G. and Drew, R. and Eogan, M. and Lambert, J. S. (2017) 'Screening for asymptomatic urogenital Chlamydia trachomatis infection at a large Dublin maternity hospital: results of a pilot study'. Ir J Med Sci, 186 (2):393-397. [DOI] [Details]
Crowley, D. and Cullen, W. and Laird, E. and Lambert, J. S. and Mc Hugh, T. and Murphy, C. and Van Hout, M. C. (2017) 'Exploring Patient Characteristics and Barriers to Hepatitis C Treatment in Patients on Opioid Substitution Treatment Attending a Community Based Fibro-scanning Clinic'. J Transl Int Med, 5 (2):112-119. [DOI] [Details]
Gray, E. and O'Leary, A. and Bergin, C. and Cannon, M. and Courtney, G. and Crosbie, O. and De Gascun, C. F. and Fanning, L. J. and Feeney, E. and Houlihan, D. D. and Kelleher, B. and Lambert, J. S. and Lee, J. and Mallon, P. and McConkey, S. and McCormick, A. and McKiernan, S. and McNally, C. and Murray, F. and Sheehan, G. and Stewart, S. and Walsh, C. and Norris, S. (2017) 'Effectiveness of interferon-free therapy for the treatment of HCV-patients with compensated cirrhosis treated through the Irish early access program'. Expert Rev Gastroenterol Hepatol, 11 (6):593-601. [DOI] [Details]
McGettrick, P. and Ghavami-Kia, B. and Tinago, W. and Macken, A. and O'Halloran, J. and Lambert, J. S. and Sheehan, G. and Mallon, P. W. G. (2017) 'The HIV Care Cascade and sub-analysis of those linked to but not retained in care: the experience from a tertiary HIV referral service in Dublin Ireland'. HIV Clin Trials, 18 (3):93-99. [DOI] [Details]
Moore, R. and Adler, H. and Jackson, V. and Lawless, M. and Byrne, M. and Eogan, M. and Lambert, J. S. (2016) 'Impaired glucose metabolism in HIV-infected pregnant women: a retrospective analysis'. Int J STD AIDS, 27 (7):581-5. [DOI] [Details]
Henihan, A. M. and McCombe, G. and Klimas, J. and Swan, D. and Leahy, D. and Anderson, R. and Bury, G. and Dunne, C. P. and Keenan, E. and Lambert, J. S. and Meagher, D. and O'Gorman, C. and O'Toole, T. P. and Saunders, J. and Shorter, G. W. and Smyth, B. P. and Kaner, E. and Cullen, W. (2016) 'Feasibility of alcohol screening among patients receiving opioid treatment in primary care'. BMC Fam Pract, 17 (1):153. [DOI] [Details]
Gray, E. and O'Leary, A. and Stewart, S. and Bergin, C. and Cannon, M. and Courtney, G. and Crosbie, O. and De Gascun, C. F. and Fanning, L. J. and Feeney, E. and Houlihan, D. D. and Kelleher, B. and Lambert, J. S. and Lee, J. and Mallon, P. and McConkey, S. and McCormick, A. and McKiernan, S. and McNally, C. and Murray, F. and Sheehan, G. and Norris, S. (2016) 'High mortality during direct acting antiviral therapy for hepatitis C patients with Child's C cirrhosis: Results of the Irish Early Access Programme'. J Hepatol, 65 (2):446-8. [DOI] [Details]
McGettrick, P. and Ferguson, W. and Jackson, V. and Eogan, M. and Lawless, M. and Ciprike, V. and Varughese, A. and Coulter-Smith, S. and Lambert, J. S. (2016) 'Syphilis serology in pregnancy: an eight-year study (2005-2012) in a large teaching maternity hospital in Dublin, Ireland'. Int J STD AIDS, 27 (3):226-30. [DOI] [Details]
McCombe, G. and Leahy, D. and Klimas, J. and Lambert, J. S. and Cullen, W. and Henihan, A. M. (2016) 'Commentary on Zeremski et al. (2016): Improvements in HCV-related Knowledge Among Substance Users on Opioid Agonist Therapy After an Educational Intervention'. J Addict Med, 10 (5):363-4. [DOI] [Details]
O'Halloran, J. A. and Dunne, E. and Gurwith, M. and Lambert, J. S. and Sheehan, G. J. and Feeney, E. R. and Pozniak, A. and Reiss, P. and Kenny, D. and Mallon, P. (2015) 'The effect of initiation of antiretroviral therapy on monocyte, endothelial and platelet function in HIV-1 infection'. HIV Med, 16 (10):608-19. [DOI] [Details]
Jackson, V. and Ferguson, W. and Kelleher, T. B. and Lawless, M. and Eogan, M. and Nusgen, U. and Coughlan, S. and Connell, J. and Lambert, J. S. (2015) 'Lamivudine treatment and outcome in pregnant women with high hepatitis B viral loads'. Eur J Clin Microbiol Infect Dis, 34 (3):619-23. [DOI] [Details]
Tinago, W. and Coghlan, E. and Macken, A. and McAndrews, J. and Doak, B. and Prior-Fuller, C. and Lambert, J. S. and Sheehan, G. J. and Mallon, P. W. (2014) 'Clinical, immunological and treatment-related factors associated with normalised CD4+/CD8+ T-cell ratio: effect of naive and memory T-cell subsets'. PLoS One, 9 (5):e97011. [DOI] [Details]
Else, L. J. and Jackson, V. and Brennan, M. and Back, D. J. and Khoo, S. H. and Coulter-Smith, S. and Lambert, J. S. (2014) 'Therapeutic drug monitoring of atazanavir/ritonavir in pregnancy'. HIV Med, 15 (10):604-10. [DOI] [Details]
Bergin, S. and Ferguson, W. and Corcoran, S. and Varughese, A. and Byrne, D. and Lawless, M. and Eogan, M. and Lambert, J. S. (2014) 'Symptomatic primary Cytomegalovirus infection in a HIV-positive pregnant woman'. Int J STD AIDS, 25 (14):1041-3. [DOI] [Details]
Adler, H. and Lambert, J. S. (2014) 'Daclatasvir for the treatment of hepatitis C virus infection'. Expert Rev Gastroenterol Hepatol, 8 (7):725-38. [DOI] [Details]
Adler, H. and Lambert, J. S. (2014) 'Clinical focus: infections in pregnancy'. Hosp Pract (1995), 42 (2):108-24. [DOI] [Details]
Adler, H. and De Gascun, C. F. and McSweeney, F. and Acheson, R. W. and Brannigan, E. T. and Duffy, M. and Keegan, D. J. and Lambert, J. S. (2014) 'Management of ganciclovir-resistant cytomegalovirus retinitis in HIV infection in the era of antiretroviral therapy'. Int J STD AIDS, 25 (11):827-9. [DOI] [Details]
Lambert, J. S. and Avramovic, G. and Jackson, V. and Sammon, N. and Lally, S. and Campbell, F. J. (2014) 'Investigation into the reasons for maternal default from HIV care postpartum: a 3-year retrospective review'. AIDS Patient Care STDS, 28 (1):1-3. [DOI] [Details]
Monteith, C. and Ni Ainle, F. and Cooley, S. and Lambert, J. S. and Kelleher, B. and Jackson, V. and Eogan, M. (2014) 'Hepatitis C virus-associated thrombocytopenia in pregnancy: impact upon multidisciplinary care provision'. J Perinat Med, 42 (1):135-8. [DOI] [Details]
Tinago, W. and O'Halloran, J. A. and O'Halloran, R. M. and Macken, A. and Lambert, J. S. and Sheehan, G. J. and Mallon, P. W. (2014) 'Characterization of associations and development of atazanavir resistance after unplanned treatment interruptions'. HIV Med, 15 (4):224-32. [DOI] [Details]
Sadlier, C. M. and Brown, A. and Lambert, J. S. and Sheehan, G. and Mallon, P. W. (2013) 'Seroprevalence of Schistosomiasis and Strongyloides infection in HIV-infected patients from endemic areas attending a European infectious diseases clinic'. AIDS Res Ther, 10 (1):23. [DOI] [Details]
Feeney, E. R. and McAuley, N. and O'Halloran, J. A. and Rock, C. and Low, J. and Satchell, C. S. and Lambert, J. S. and Sheehan, G. J. and Mallon, P. W. (2013) 'The expression of cholesterol metabolism genes in monocytes from HIV-infected subjects suggests intracellular cholesterol accumulation'. J Infect Dis, 207 (4):628-37. [DOI] [Details]
Ganis, J. J. and Hsia, N. and Trompouki, E. and de Jong, J. L. and DiBiase, A. and Lambert, J. S. and Jia, Z. and Sabo, P. J. and Weaver, M. and Sandstrom, R. and Stamatoyannopoulos, J. A. and Zhou, Y. and Zon, L. I. (2012) 'Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR'. Dev Biol, 366 (2):185-94. [DOI] [Details]
O'Halloran, J. A. and De Gascun, C. F. and Dunford, L. and Carr, M. J. and Connell, J. and Howard, R. and Hall, W. W. and Lambert, J. S. (2011) 'Hepatitis B virus vaccine failure resulting in chronic hepatitis B infection'. J Clin Virol, 52 (2):151-4. [DOI] [Details]
Caswell, R. J. and Phillips, D. and Chaponda, M. and Khoo, S. H. and Taylor, G. P. and Ghanem, M. and Poulton, M. and Welch, J. and Gibbons, S. and Jackson, V. and Lambert, J. S. (2011) 'Utility of therapeutic drug monitoring in the management of HIV-infected pregnant women in receipt of lopinavir'. Int J STD AIDS, 22 (1):11-4. [DOI] [Details]
Lambert, J. S. and Else, L. J. and Jackson, V. and Breiden, J. and Gibbons, S. and Dickinson, L. and Back, D. J. and Brennan, M. and Connor, E. O. and Boyle, N. and Fleming, C. and Coulter-Smith, S. and Khoo, S. H. (2011) 'Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy'. HIV Med, 12 (3):166-73. [DOI] [Details]
Satchell, C. S. and O'Halloran, J. A. and Cotter, A. G. and Peace, A. J. and O'Connor, E. F. and Tedesco, A. F. and Feeney, E. R. and Lambert, J. S. and Sheehan, G. J. and Kenny, D. and Mallon, P. W. (2011) 'Increased platelet reactivity in HIV-1-infected patients receiving abacavir-containing antiretroviral therapy'. J Infect Dis, 204 (8):1202-10. [DOI] [Details]
Satchell, C. S. and Cotter, A. G. and O'Connor, E. F. and Peace, A. J. and Tedesco, A. F. and Clare, A. and Lambert, J. S. and Sheehan, G. J. and Kenny, D. and Mallon, P. W. (2010) 'Platelet function and HIV: a case-control study'. Aids, 24 (5):649-57. [DOI] [Details]
Coulter-Smith, S. and Lambert, J. S. and Butler, K. and Brennan, M. and Cafferkey, M. (2010) 'HIV testing and treatment in the antenatal care setting'. Ir Med J, 103 (1):14-7. [Details]
Roe, B. and Coughlan, S. and Dean, J. and Lambert, J. S. and Keating, S. and Norris, S. and Bergin, C. and Hall, W. W. (2009) 'Phenotypic characterization of lymphocytes in HCV/HIV co-infected patients'. Viral Immunol, 22 (1):39-48. [DOI] [Details]
Machado, E. S. and Hofer, C. B. and Costa, T. T. and Nogueira, S. A. and Oliveira, R. H. and Abreu, T. F. and Evangelista, L. A. and Farias, I. F. and Mercadante, R. T. and Garcia, M. F. and Neves, R. C. and Costa, V. M. and Lambert, J. S. (2009) 'Pregnancy outcome in women infected with HIV-1 receiving combination antiretroviral therapy before versus after conception'. Sex Transm Infect, 85 (2):82-7. [DOI] [Details]
Samuel, M. and Aderogba, K. and Dutt, N. and Lambert, J. S. and Taylor, C. (2007) 'A hat trick of ulcerating pathogens in a single genital lesion'. Int J STD AIDS, 18 (1):65-6. [DOI] [Details]
Lambert, J. S. and Machado, E. S. and Watson, D. C. and Sill, A. M. and Lim, J. K. and Charurat, M. and Cunha, S. M. and Afonso, A. O. and Oliviera, R. H. and Tanuri, A. and DeVico, A. L. (2007) 'Production of the HIV-suppressive chemokines CCL3/MIP-1alpha and CCL22/MDC is associated with more effective antiretroviral therapy in HIV-infected children'. Pediatr Infect Dis J, 26 (10):935-44. [DOI] [Details]
Lambert, J. S. (2007) 'Long-term follow-up of a quadrivalent HPV vaccine'. Expert Rev Vaccines, 6 (2):141-5. [DOI] [Details]
McMillan, H. M. and O'Carroll, H. and Lambert, J. S. and Grundy, K. B. and O'Reilly, M. and Lennon, B. and Collins, C. and Walsh, T. A. and Geary, M. P. and Cafferkey, M. T. (2006) 'Screening for Chlamydia trachomatis in asymptomatic women attending outpatient clinics in a large maternity hospital in Dublin, Ireland'. Sex Transm Infect, 82 (6):503-5. [DOI] [Details]
McFarland, E. J. and Johnson, D. C. and Muresan, P. and Fenton, T. and Tomaras, G. D. and McNamara, J. and Read, J. S. and Douglas, S. D. and Deville, J. and Gurwith, M. and Gurunathan, S. and Lambert, J. S. (2006) 'HIV-1 vaccine induced immune responses in newborns of HIV-1 infected mothers'. Aids, 20 (11):1481-9. [DOI] [Details]
Lambert, J. S. and Moye, J., Jr. and Plaeger, S. F. and Stiehm, E. R. and Bethel, J. and Mofenson, L. M. and Mathieson, B. and Kagan, J. and Rosenblatt, H. and Paxton, H. and Suter, H. and Landay, A. (2005) 'Association of selected phenotypic markers of lymphocyte activation and differentiation with perinatal human immunodeficiency virus transmission and infant infection'. Clin Diagn Lab Immunol, 12 (5):622-31. [DOI] [Details]
Chew, N. and Lambert, J. S. (2005) 'Meeting report of the 10th European AIDS Conference (EACS) 17-20 November 2005'. J HIV Ther, 10 (4):79-80. [Details]
Machado, E. S. and Lambert, J. S. and Afonso, A. O. and Cunha, S. M. and Oliveira, R. H. and Tanuri, A. and Sill, A. M. and Costa, A. J. and Soares, M. A. (2004) 'Alternative, age- and viral load-related routes of nelfinavir resistance in human immunodeficiency virus type 1-infected children receiving highly active antiretroviral therapy'. Pediatr Infect Dis J, 23 (11):1057-9. [Details]
Machado, E. S. and Lambert, J. S. and Watson, D. C. and Afonso, A. O. and da Cunha, S. M. and Nogueira, S. A. and Caride, E. and Oliveira, R. H. and Sill, A. M. and DeVico, A. and Tanuri, A. (2004) 'Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy'. J Clin Virol, 30 (1):24-31. [DOI] [Details]
Machado, E. S. and Lambert, J. S. and Afonso, A. O. and Cunha, S. M. and Oliveira, R. H. and Tanuri, A. and Sill, A. M. and Soares, M. A. (2004) 'Overview of genotypic and clinical profiles of human immunodeficiency virus type 1-infected children in Rio de Janeiro, Brazil'. An Acad Bras Cienc, 76 (4):727-41. [DOI] [Details]
Lambert, J. S. and Nogueira, S. A. and Abreu, T. and Machado, E. S. and Costa, T. P. and Bondarovsky, M. and Andrade, M. and Halpern, M. and Barbosa, R. and Perez, M. (2003) 'A pilot study to evaluate the safety and feasibility of the administration of AZT/3TC fixed dose combination to HIV infected pregnant women and their infants in Rio de Janeiro, Brazil'. Sex Transm Infect, 79 (6):448-52. [Details]
Lambert, J. S. and Harris, D. R. and Stiehm, E. R. and Moye, J., Jr. and Fowler, M. G. and Meyer, W. A., 3rd and Bethel, J. and Mofenson, L. M. (2003) 'Performance characteristics of HIV-1 culture and HIV-1 DNA and RNA amplification assays for early diagnosis of perinatal HIV-1 infection'. J Acquir Immune Defic Syndr, 34 (5):512-9. [Details]
Madhivanan, P. and Mothi, S. N. and Kumarasamy, N. and Yepthomi, T. and Venkatesan, C. and Lambert, J. S. and Solomon, S. (2003) 'Clinical manifestations of HIV infected children'. Indian J Pediatr, 70 (8):615-20. [Details]
Nogueira, C. A. and Edelman, D. C. and Nogueira, C. M. and Nogueira, S. A. and Coelho, H. S. and Abrahao, L. J. and Vanderboght, B. and Lambert, J. S. and Constantine, N. T. (2002) 'Hepatitis C virus transfusion-transmitted infection in Brazilian cardiac surgery patients'. Clin Lab, 48 (9-10):529-33. [Details]
Nogueira, S. A. and Guedes, A. L. and Machado, E. S. and Matos, J. A. and Costa, T. P. and Cortes, E. M. and Lambert, J. S. (2002) 'Toxoplasmic encephalitis in an HIV infected pregnant woman: successful outcome for both mother and child'. Braz J Infect Dis, 6 (4):201-5. [Details]
Villela Nogueira, C. A. and Nogueira, S. A. and Nogueira, C. N. and Coelho, H. S. and Ketema, F. and Edelman, D. C. and Lambert, J. S. and Constantine, N. T. (2001) 'The incidence of GB virus C / hepatitis G virus infection in Brazilian patients who received blood transfusion during cardiac surgery'. J Med Virol, 63 (3):237-41. [Details]
Ferreira, E. and Lucena, S. and Fonseca, G. and Barbosa, T. C. and Aquino, R. B. and Lambert, J. S. and Nogueira, S. A. (2001) 'Visceral leishmaniasis in a Brazilian child infected perinatally with human immunodeficiency virus'. Pediatr Infect Dis J, 20 (2):224-6. [Details]
Gazineo, J. L. and Trope, B. M. and Maceira, J. P. and May, S. B. and Coelho, J. M. and Lambert, J. S. and Nogueira, S. A. (2001) 'Bacillary angiomatosis: description of 13 cases reported in five reference centers for AIDS treatment in Rio de Janeiro, Brazil'. Rev Inst Med Trop Sao Paulo, 43 (1):1-6. [Details]
Lambert, J. S. and Keefer, M. and Mulligan, M. J. and Schwartz, D. and Mestecky, J. and Weinhold, K. and Smith, C. and Hsieh, R. and Moldoveanu, Z. and Fast, P. and Forrest, B. and Koff, W. (2001) 'A Phase I safety and immunogenicity trial of UBI microparticulate monovalent HIV-1 MN oral peptide immunogen with parenteral boost in HIV-1 seronegative human subjects'. Vaccine, 19 (23-24):3033-42. [Details]
Nogueira, S. A. and Lambert, J. S. and Albuquerque, A. L. and Rodrigues, R. and Reis, S. and Bornia, R. and Dias, M. and Barbosa, R. and Sztanjbock, D. and Santos, A. L. and Blattner, W. and Constantine, N. T. (2001) 'Assessment of a rapid HIV test strategy during labor: a pilot study from Rio de Janeiro, Brazil'. J Hum Virol, 4 (5):278-82. [Details]
Nogueira, S. A. and Guedes, A. L. and Wanke, B. and Capella, S. and Rodrigues, K. and Abreu, T. F. and Morais, J. C. and Lambert, J. S. (2001) 'Osteomyelitis caused by Paracoccidioides brasiliensis in a child from the metropolitan area of Rio de Janeiro'. J Trop Pediatr, 47 (5):311-5. [Details]
Nogueira, S. A. and Abreu, T. and Oliveira, R. and Araujo, L. and Costa, T. and Andrade, M. and Garcia Psic, M. F. and Machado and Rodrigues, K. and Mercadante, R. and Fernandes, I. and Sapia, M. C. and Lambert, J. S. (2001) 'Successful prevention of hiv transmission from mother to infant in Brazil using a multidisciplinary team approach'. Braz J Infect Dis, 5 (2):78-86. [Details]
Watts, D. H. and Lambert, J. S. and Stiehm, E. R. and Bethel, J. and Whitehouse, J. and Fowler, M. G. and Read, J. (2000) 'Complications according to mode of delivery among human immunodeficiency virus-infected women with CD4 lymphocyte counts of < or=500/microL'. Am J Obstet Gynecol, 183 (1):100-7. [Details]
Chuachoowong, R. and Shaffer, N. and VanCott, T. C. and Chaisilwattana, P. and Siriwasin, W. and Waranawat, N. and Vanprapar, N. and Young, N. L. and Mastro, T. D. and Lambert, J. S. and Robb, M. L. (2000) 'Lack of association between human immunodeficiency virus type 1 antibody in cervicovaginal lavage fluid and plasma and perinatal transmission, in Thailand'. J Infect Dis, 181 (6):1957-63. [DOI] [Details]
Abreu, T. and Plaisance, K. and Rexroad, V. and Nogueira, S. and Oliveira, R. H. and Evangelista, L. A. and Rangel, R. and Silva, I. S. and Knupp, C. and Lambert, J. S. (2000) 'Bioavailability of once- and twice-daily regimens of didanosine in human immunodeficiency virus-infected children'. Antimicrob Agents Chemother, 44 (5):1375-6. [Details]
King, J. C., Jr. and Treanor, J. and Fast, P. E. and Wolff, M. and Yan, L. and Iacuzio, D. and Readmond, B. and O'Brien, D. and Mallon, K. and Highsmith, W. E. and Lambert, J. S. and Belshe, R. B. (2000) 'Comparison of the safety, vaccine virus shedding, and immunogenicity of influenza virus vaccine, trivalent, types A and B, live cold-adapted, administered to human immunodeficiency virus (HIV)-infected and non-HIV-infected adults'. J Infect Dis, 181 (2):725-8. [DOI] [Details]
Lambert, J. S. and Watts, D. H. and Mofenson, L. and Stiehm, E. R. and Harris, D. R. and Bethel, J. and Whitehouse, J. and Jimenez, E. and Gandia, J. and Scott, G. and O'Sullivan, M. J. and Kovacs, A. and Stek, A. and Shearer, W. T. and Hammill, H. and van Dyke, R. and Maupin, R. and Silio, M. and Fowler, M. G. (2000) 'Risk factors for preterm birth, low birth weight, and intrauterine growth retardation in infants born to HIV-infected pregnant women receiving zidovudine. Pediatric AIDS Clinical Trials Group 185 Team'. Aids, 14 (10):1389-99. [Details]
Stiehm, E. R. and Lambert, J. S. and Mofenson, L. M. and Bethel, J. and Whitehouse, J. and Nugent, R. and Moye, J., Jr. and Glenn Fowler, M. and Mathieson, B. J. and Reichelderfer, P. and Nemo, G. J. and Korelitz, J. and Meyer, W. A., 3rd and Sapan, C. V. and Jimenez, E. and Gandia, J. and Scott, G. and O'Sullivan, M. J. and Kovacs, A. and Stek, A. and Shearer, W. T. and Hammill, H. (1999) 'Efficacy of zidovudine and human immunodeficiency virus (HIV) hyperimmune immunoglobulin for reducing perinatal HIV transmission from HIV-infected women with advanced disease: results of Pediatric AIDS Clinical Trials Group protocol 185'. J Infect Dis, 179 (3):567-75. [DOI] [Details]
Lambert, J. S. and Moye, J. J. (1999) 'Current issues in the immunoprophylaxis of vertical transmission of HIV'. BioDrugs, 11 (1):31-41. [Details]
Mofenson, L. M. and Lambert, J. S. and Stiehm, E. R. and Bethel, J. and Meyer, W. A., 3rd and Whitehouse, J. and Moye, J., Jr. and Reichelderfer, P. and Harris, D. R. and Fowler, M. G. and Mathieson, B. J. and Nemo, G. J. (1999) 'Risk factors for perinatal transmission of human immunodeficiency virus type 1 in women treated with zidovudine. Pediatric AIDS Clinical Trials Group Study 185 Team'. N Engl J Med, 341 (6):385-93. [DOI] [Details]
Wright, P. F. and Lambert, J. S. and Gorse, G. J. and Hsieh, R. H. and McElrath, M. J. and Weinhold, K. and Wara, D. W. and Anderson, E. L. and Keefer, M. C. and Jackson, S. and Wagner, L. J. and Francis, D. P. and Fast, P. E. and McNamara, J. (1999) 'Immunization with envelope MN rgp120 vaccine in human immunodeficiency virus-infected pregnant women'. J Infect Dis, 180 (4):1080-8. [DOI] [Details]
Nogueira, S. A. and Caiuby, M. J. and Vasconcelos, V. and Halpern, M. and Gouveia, C. and Thorpe, B. and Ramparini, C. and Macieira, J. M. and Lambert, J. S. (1998) 'Paracoccidioidomycosis and tuberculosis in AIDS patients: report of two cases in Brazil'. Int J Infect Dis, 2 (3):168-72. [Details]
Graham, B. S. and McElrath, M. J. and Connor, R. I. and Schwartz, D. H. and Gorse, G. J. and Keefer, M. C. and Mulligan, M. J. and Matthews, T. J. and Wolinsky, S. M. and Montefiori, D. C. and Vermund, S. H. and Lambert, J. S. and Corey, L. and Belshe, R. B. and Dolin, R. and Wright, P. F. and Korber, B. T. and Wolff, M. C. and Fast, P. E. (1998) 'Analysis of intercurrent human immunodeficiency virus type 1 infections in phase I and II trials of candidate AIDS vaccines. AIDS Vaccine Evaluation Group, and the Correlates of HIV Immune Protection Group'. J Infect Dis, 177 (2):310-9. [Details]
Funkhouser, A. W. and Katzman, P. J. and Sickel, J. Z. and Lambert, J. S. (1998) 'CD30-positive anaplastic large cell lymphoma (ALCL) of T-cell lineage in a 14-month-old infant with perinatally acquired HIV-1 infection'. J Pediatr Hematol Oncol, 20 (6):556-9. [Details]
Lambert, J. S. and McNamara, J. and Katz, S. L. and Fenton, T. and Kang, M. and VanCott, T. C. and Livingston, R. and Hawkins, E. and Moye, J., Jr. and Borkowsky, W. and Johnson, D. and Yogev, R. and Duliege, A. M. and Francis, D. and Gershon, A. and Wara, D. and Martin, N. and Levin, M. and McSherry, G. and Smith, G. (1998) 'Safety and immunogenicity of HIV recombinant envelope vaccines in HIV-infected infants and children. National Institutes of Health-sponsored Pediatric AIDS Clinical Trials Group (ACTG-218)'. J Acquir Immune Defic Syndr Hum Retrovirol, 19 (5):451-61. [Details]
Lambert, J. S. and Viscidi, R. and Walker, M. C. and Clayman, B. and Winget, M. and Wolff, M. and Schwartz, D. H. (1997) 'Antibody to human immunodeficiency virus type 1 (HIV-1) gp160 in mucosal specimens of asymptomatic HIV-1-infected volunteers parenterally immunized with an experimental recombinant HIV-1 IIIB gp160 vaccine. The National Institute of Allergy and Infectious Diseases-sponsored AIDS Vaccine Evaluation Group'. Clin Diagn Lab Immunol, 4 (3):302-8. [Details]
Lambert, J. S. and Mofenson, L. M. and Fletcher, C. V. and Moye, J., Jr. and Stiehm, E. R. and Meyer, W. A., 3rd and Nemo, G. J. and Mathieson, B. J. and Hirsch, G. and Sapan, C. V. and Cummins, L. M. and Jimenez, E. and O'Neill, E. and Kovacs, A. and Stek, A. (1997) 'Safety and pharmacokinetics of hyperimmune anti-human immunodeficiency virus (HIV) immunoglobulin administered to HIV-infected pregnant women and their newborns. Pediatric AIDS Clinical Trials Group Protocol 185 Pharmacokinetic Study Group'. J Infect Dis, 175 (2):283-91. [Details]
Mascola, J. R. and Louder, M. K. and VanCott, T. C. and Sapan, C. V. and Lambert, J. S. and Muenz, L. R. and Bunow, B. and Birx, D. L. and Robb, M. L. (1997) 'Potent and synergistic neutralization of human immunodeficiency virus (HIV) type 1 primary isolates by hyperimmune anti-HIV immunoglobulin combined with monoclonal antibodies 2F5 and 2G12'. J Virol, 71 (10):7198-206. [Details]
Lambert, J. S. (1996) 'Pediatric HIV infection'. Curr Opin Pediatr, 8 (6):606-14. [Details]
Lambert, J. S. (1995) 'The prevention of maternal-fetal HIV-1 infection through passive antibody products (HIVIG) and active immunization (AIDS vaccines)'. Pediatr AIDS HIV Infect, 6 (5):300-2. [Details]
Hausler, H. and Lambert, J. S. (1994) 'Preparation for HIV vaccine trials: ethical, behavioral, and social issues'. Pediatr AIDS HIV Infect, 5 (4):238-43. [Details]
Lambert, J. S. and Stiehm, E. R. (1993) 'Passive immunity in the prevention of maternal-fetal transmission of human immunodeficiency virus infection'. Ann N Y Acad Sci, 693 :186-93. [Details]
Lambert, J. S. (1993) 'Maternal-fetal transmission of HIV-1 infection'. Pediatr Ann, 22 (7):413-6. [Details]
Seidlin, M. and Lambert, J. S. and Dolin, R. and Valentine, F. T. (1992) 'Pancreatitis and pancreatic dysfunction in patients taking dideoxyinosine'. Aids, 6 (8):831-5. [Details]
Drusano, G. L. and Yuen, G. J. and Morse, G. and Cooley, T. P. and Seidlin, M. and Lambert, J. S. and Liebman, H. A. and Valentine, F. T. and Dolin, R. (1992) 'Impact of bioavailability on determination of the maximal tolerated dose of 2',3'-dideoxyinosine in phase I trials'. Antimicrob Agents Chemother, 36 (6):1280-3. [Details]
Drusano, G. L. and Yuen, G. J. and Lambert, J. S. and Seidlin, M. and Dolin, R. and Valentine, F. T. (1992) 'Relationship between dideoxyinosine exposure, CD4 counts, and p24 antigen levels in human immunodeficiency virus infection. A phase I trial'. Ann Intern Med, 116 (7):562-6. [Details]
Cullen, J. B. and Baram, D. A. and Sherer, D. M. and Woods, J. R., Jr. and Lambert, J. S. and Reichman, R. C. (1992) 'Woman with AIDS presented for elective termination of pregnancy'. Am J Perinatol, 9 (4):313. [Details]
Kieburtz, K. D. and Seidlin, M. and Lambert, J. S. and Dolin, R. and Reichman, R. and Valentine, F. (1992) 'Extended follow-up of peripheral neuropathy in patients with AIDS and AIDS-related complex treated with dideoxyinosine'. J Acquir Immune Defic Syndr, 5 (1):60-4. [Details]
Sperling, R. S. and Stratton, P. and O'Sullivan, M. J. and Boyer, P. and Watts, D. H. and Lambert, J. S. and Hammill, H. and Livingston, E. G. and Gloeb, D. J. and Minkoff, H. and et al. (1992) 'A survey of zidovudine use in pregnant women with human immunodeficiency virus infection'. N Engl J Med, 326 (13):857-61. [DOI] [Details]
Ukwu, H. N. and Graham, B. S. and Lambert, J. S. and Wright, P. F. (1992) 'Perinatal transmission of human immunodeficiency virus-1 infection and maternal immunization strategies for prevention'. Obstet Gynecol, 80 (3 Pt 1):458-68. [Details]
Lambert, J. S. and Seidlin, M. and Reichman, R. C. and Plank, C. S. and Laverty, M. and Morse, G. D. and Knupp, C. and McLaren, C. and Pettinelli, C. and Valentine, F. T. and et al. (1990) '2',3'-dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex. A phase I trial'. N Engl J Med, 322 (19):1333-40. [DOI] [Details]
Lambert, J. S. (1990) 'Maternal and perinatal issues regarding HIV infection'. Pediatr Ann, 19 (8):468-72. [Details]

Other Journals

Lambert JS et al. ; (2007) 'Production of the HIV Suppressive Chemokines CCL3/MIP-1? and CCL22/MDC is Associated with More Effective Antiretroviral Therapy in HIV-Infected Children' Pediatric Infectious Disease Journal . [Details]
McMillan, H.M., O'Carroll, H., Lambert, J.S., Brundy, K.B., O'Reilly, M., Lennon, B., Collins, C., Walsh, T.A., Geary, M.P. Cafferkey, M.T.; (2006) 'Screening for Chlamydia trachomatis in asymptomatic women attending outpatient clincks in a large maternity hospital in Dublin, Ireland' Sex Transm Infect . [Details]
Lambert JS, Clapson M.; (2005) 'In search of a paediatric HIV vaccine: scientific and ethical issues' HIV Nursing 5 (4) . [Details]
Lambert, J.S.; (2005) 'HIV vaccines in infants and children' Paediatr Drugs . [Details]
Lambert, J.S., Moye, J. Jr., Plaeger, S.F., Stiehm, E.R., Bethel, J., Mofenson, L.M., Mathieson, B., Kagan, J., roseblatt, H., Paxton, H., Suter, H., Landay, A.; (2005) 'Association of selected phenotypic markers of lymphocyte activation and differentiation with perinatal human immunodeficienty virus transmission and infant infection' Clin Diagn Lam Immunol . [Details]

Conference Publications

O'Halloran, J; Herlihy, T; Macken, A; Rainford, L; Lambert, J; Sheehan, G; Mahon, N; Lawler, L; Mallon, P (2015) Enhanced, not Inhibited Monocyte Cholesterol Efflux Characterises Untreated HIV Conference on Retroviruses and Opportunistic Infections (CROI) [Details]
McMenamin, MB,Jackson, AD,Lambert, J,Hall, W,Butler, K,Coulter-Smith, S,McAuliffe, FM (2008) AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY Obstetric management of hepatitis C-positive mothers: analysis of vertical transmission in 559 mother-infant pairs [DOI] [Details]
McFarland, EJ,Johnson, DC,Muresan, P,Fenton, T,Tomaras, GD,McNamara, J,Read, JS,Douglas, SD,Deville, J,Gurwith, M,Gurunathan, S,Lambert, JS (2006) AIDS HIV-1 vaccine induced immune responses in newborns of HIV-1 infected mothers , pp.1481-1489 [Details]
                 

Manual

Lambert JS, Nogueira SA, Joshi Shubhada Y; (2004) Manual for the care of HIV infected children. Bombay, India: Manual [Details]
Lambert JS, Nogueira SA, Saraogi RM.; (2004) Manual for the clinical care of HIV infected pregnant women. Bombay, India: Manual [Details]
                     

Abstract

Satchell, CS,O'Halloran, JA,Peace, AJ,O'Connor, EF,Cotter, AG,Feeney, ER,Sheehan, GJ,Lambert, JS,Kenny, D,Mallon, PWG (2010) Inflammation and impaired renal function do not explain increased platelet reactivity in patients on abacavir-containing antiretroviral therapy. Abstract [Details]
Cotter, AG,Satchell, CS,O'Halloran, J,Feeney, ER,O'Connor, E,Sheehan, G,Lambert, J,Sabin, CA,Mallon, PWG (2010) The protease inhibitor atazanavir and predictors of prolonged QT interval in HIV-1 infected patients. Abstract [Details]
McMenamin, M,Jackson, A,Lambert, J,Smith, SC,Jones, L,McAuliffe, F (2007) Vertical transmission of hepatitis C. Abstract [DOI] [Details]
                                                                   

LETTER

Gray E, O'Leary A;Stewart S;Bergin C;Cannon M;Courtney G;Crosbie O;De Gascun CF;Feeney E;Houlihan DD;Kelleher B;Lambert JS;Lee J;Mallon P;McConkey S;McCormick A;McKiernan S;McNally C;Murray F;Sheehan G;Norris S;Fanning LJ; (2016) High mortality during direct acting antiviral therapy for hepatitis C patients with Child's C cirrhosis: Results of the Irish Early Access Programme. LETTER [DOI] [Details]
Lambert JS, Avramovic G;Jackson V;Sammon N;Lally S;Campbell FJ (2014) Investigation into the reasons for maternal default from HIV care postpartum: a 3-year retrospective review. LETTER [DOI] [Details]
                     

Research

Research Interests

1.                   ACTG 064. A Phase 1 study of the safety and immunogenicity of DDI administered twice daily to HIV infected adults. (Clinical director of Study; PI Dr Ray Dolin).

2.                   ACTG 185 A Phase 3 Efficacy Trial of HIVIG administered to HIV infected pregnant women and their newborns. (Principal Investigator of the study).

3.                   ACTG 218 A Phase 1/2 Safety and Immunogenicity study of HIV vaccines administered to HIV infected children. (PI, Study Co-Chair)

4.                   ACTG 326 A Phase 1/2 Safety and immunogenicity study of HIV vaccines administered to HIV exposed children (PI, Study Chair)

5.                   AVEG 102 A Phase 1 study of an HIV vaccine (microgenesys) administered to HIV infected Pregnant women. (PI, Study Co-chair)

6.                   AVEG 104 A Phase 1 study of an HIV vaccine (genentech) administered to HIV infected pregnant women (PI, study Co-Chair)

7.                   AVEG 018 A Phase 2 study on an UBI microparticulate oral vaccine administered to HIV low risk seronegative adults. (PI, study chair)

8.                   Biovir Study A Phase 1/2 study of Combivir administered to HIV infected pregnant women and their newborns in an outpatient clinic in Rio de Janeiro, Brazil. (PI, study Co-Chair).

9.                   Hepatitis B Study A Phase 1/2 study of the administration of a Hepatitis B vaccine to newborns born to HIV infected mothers, Sao Paolo, Brazil. (study PI)

10.               Penta 10/MRC A Phase 2 study of the administration of IL-2 to HIVinfected children followed as part of the European Paediatric HIV network. (study co-chair)

11.               Brazil DDI Study A Phase 1 study of the bioequivelance of once daily versus twice daily DDI administered to HIV infected children. (study PI)

12.               Fiocruz Study Establishment of a high risk gay mens cohort, assessing risk of acquisition of STD's in this population followed at the Oswaldo Cruz Foundation, Rio de Janeiro, Brazil (Co investigator)

13.               Trichomonas Study: Evaluation of the prevalence of asymptomatic carriage of trichomonas in men attending the STD clinic at the Monroe County Health Department, Rochester NY

14.               Herpes Study: Evaluation of a rapid HSV test kit in a population of STD patients followed at the Monroe County STD clinic, Rochester NY (co-investigator).

15.               STD in Pregnant Women Study Establishment of a Cohort of High risk pregnant women at Fernandez Figeroia Institute, Rio de Janeiro, Brazil, and measurement of prevalence of STDs in this population. Comparison of standard culture techniques with LCR/PCR for GC and chlamydia . (PI, student mentor)

16.               Uganda Peds vaccine study Assessment of attitudes to vaccination in a paediatric clinic in rural Uganda (student mentor)

17.               HIV and syphilis study; Evaluation and characterization of pregnant women co-infected with syphilis and HIV in a pre-natal clinic in Rochester NY (study PI)

18.               Paracoccidiomycosis and HIV Characterization of the association of paracoccidio and HIV (study co-investigator).

19.               Post transfusion hepatitis C study Prevalence and incidence of Hepatitis C in a cohort of transplant patients followed at the Federal University of rio de Janeiro, Brazil. (thesis advisor)

20.               Rapid HIV testing study-Rio de Janeiro and Port of Spain, Trinidad and Tobago. Study of the feasibilty of HIV rapid testing used in labor and delivery for the rapid diagnosis and treatment of HIV infected pregnant women. (study PI)

21.               CDC cervical lavage study Measurement of mucosal antibody from cervical lavage specimens taken from HIV infected pregnant women who were part of the CDC/Thai AZT MTCT study. (consultant to CDC for mucosal immunity study, thesis advisor for student PhD thesis Dr Rutt)

22.               Bacillary angiomatosis study Study of the characterization of relationship and manifestations of HIV and bacillary angiomatosis co-infected patients from a series of hospitals in Rio de Janeiro, Brazil (co-investigator).
MCTC cohort Chennai Establishment and characterization of a cohort of HIV infected pregnant women followed at a tertiary Care centre, YRG, in Chennai, India (student mentor, co-investigator).

23.               Paediatric HIV cohort Chennai Establishment and characterization of a cohort of HIV infected children followed at the YRG medical clinic in Chennai, India (student mentor, co-investigator).

24.               MTCT cohort Rio Establishment of a cohort of HIV infected pregnant women from the maternities of the Federal University of Rio de Janeiro, Brazil (co-PI).

25.               Paed AIDS cohort Rio Establishment of a cohort of HIV infected and exposed children followed at the Federal University of Rio de Janeiro, Brazil, (co-PI).

26.               Seroprevalence of STD in PG women cohort Rio Establishment and characterization of STD's found in a cohort of pregnant women followed at the State University of Rio de Janeiro, Brazil, (study co-PI and thesis advisor).
Hepatitis G study Rio Assessment of the prevalence of hepatitis G in a cohort from the Federal University of Rio de Janeiro, Brazil. (study co-PI and thesis advisor)

27.               Pneumococcal vaccine study in HIV infected adults Assessment of the safety and immunogenicity of a conjugate Pn Vaccine in adults with symptomatic HIV infection. (study PI)

28.               Transmission of HIV Subtypes in MTCT: Evaluation of the fidelity of transmission of chimeric HIV from mother to child in the Rio de Janeiro cohort. (study co-PI)

29.               Quest study--quad therapy. Thymic reconstitution following HAART therapy in a cohort of adults followed in a multicentred GSK sponsored study (co-investigator).

30.               Genotypic analysis of HIV infected children: Establishment of cohort and evaluation of genotypic resistance, following therapy, in children followed in the specialty clinics of the Federal University of Rio de Janeiro Brazil. (PI).

31.               Protocol A4001050: A multi-centre open label expanded access trial of Maraviroc

32.               Protocol M05-730: A phase III, randomised, open label, study of Lopinavir/ritonavir tablets versus soft gel capsules and once daily versus twice daily administration, when co-administered with NRTIs in antiretroviral naïve HIV-1 infected subjects

33.               Protocol AI424136: A phase IV, open-label, randomised, multicentre trial assessing the efficacy of a treatment maintenance phase with unboosted vs. boosted Reyataz after an induction phase with Reyataz and Ritonavir in treatment naïve HIV patients (the INDUMA Study)

34.               Euroresistance Study: Strategy to control spread of HIV drug resistance. Official European Commission supported programme

35.               Therapeutic drug monitoring: use in HIV infected pregnant women

36.               Immune response to Tuberculosis in people with and without HIV infection

37.               Protocol M06-802: A phase III, randomised, open label study of Lopinavir/ritonavir tablets 800/200mg once-daily versus 400/100mg twice-daily when co-administered with Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in antiretroviral-experienced, HIV-1 infected subjects

38.               Protocol CNA1095586: Study of Once Daily Abacavir/ Lamivudine versus Tenofir/ Emtricitabime, administered with Efavirenz in antiretroviral niave HIV-1 infected adult subjects.

39.               Barriers to and enablers of hepatitis C screening and treatment among current or former injecting drug users in Ireland:        A qualitative study from two perspectives.  Co investigator with Dr Walter Cullen, PI.

40.               Community Based Hepatitis C Treatment Study: Thompson Street Centre, Dublin 1.  (PI)

41.               Dublin HIV Cohort Study:     Recruitment of patients with HIV from the major teaching hospitals in Dublin.  (Co-Investigator)

42.               Telzir/Hepatitis C Study:        Phase 4 study of telzir treatment in patients with HepC coinfection (PI)

43.               Protocol AI 447-016             A phase 2a/2b study of BMS-650032 in Combination with Peginterferon Alfa-2a (Pegasys) and Ribavirin (Copegus) in Treatment-Naïve Subjects with Genotypes 1 and 4 Chronic Hepatitis C Infection.

44.               Protocol AI444010                A phase 2B Study of BMS-790052 in Combination with Peginterferon Alfa-2a (Pegasys) and Ribavirin in Treatment Naïve Subjects with Chronic Hepatitis C Genotype 1 and 4 infection.

45.               S-COLLATE Study               A Multicentre, Prospective, Observational, Non-Interventional Cohort Study Evaluating On-Treatment Predictors of Response in Subjects with HbeAg positive or HbeAg negative Chronic Hepatitis B Receiving Therapy with PEGASYS® (Peginterferon alfa-2a 40 KD)

46.               Protocol GS-US-196-0103  A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Trial comparing 24 or 48 weeks of GS-9190, in Combination with Peginterferon Alpha 2a and Ribavirin, to 48 weeks of Peginterferon Alpha 2a and Ribavirin for the Treatment of Genotype-1 Chronic Hepatitis C Virus (HCV) Infection

47.               Investigation into the reasons for HIV infected women not following up for their own care postpartum. MMUH/Rotunda. PI.

48.               PANNA study              Study on Pharmacokinetics of newly developed Antiretroviral agents in HIV-infected pregnant women (PANNA).

49.               Therapeutic Drug Monitoring of Protease Inhibitors in Pregnancy as a Standard of Care¿

50.               A community based Hepatitis C treatment programme. 

51.               Friends of Rotunda ¿Screening for Hepatitis C: a prospective study at the Rotunda Maternity Hospital Dublin Ireland¿.

52.               Telzir treatment of patients co-infected with HIV and Hepatitis C.

53.               Woody Woodpecker Foundation to establish a MMUH/UCD link with Baphumelele Children¿s AIDS home, Capetown RSA

54.               AI444-026 An Open-Label Re-treatment Study with Peg-Interferon Alfa-2a, Ribavirin and BMS-790052 With or Without BMS-650032 for Subjects With Chronic Hepatitis C, BMS.

55.               AI447-028: Phase 3 Study with Asunaprevir and Daclatasvir (DUAL) for Null or Partial Responders to Peginterferon Alfa and Ribavirin (P/R), Intolerant or Ineligible to P/R Subjects and Treatment-Naive Subjects with Chronic Hepatitis C Genotype 1b Infection, BMS.

56.               BI1241.20             A Phase III, Randomised, Partially Double-Blind and Placebo-Controlled Study of BI 207127 in Combination with FaldaprevirandRibavirin in Treatment-Naïve Patients with Chronic Genotype 1 HCVInfection, Boehringer Ingelheim.

57.               Audit of HIV infected children in East London, RSA.

58.               Global Adolescent HIV Research Project: The Passages Project

59.               Homeless HepCheck.

60.               PMTCT/ young adult ARV, RSA, PHASE 2.

61.               Audit of HIV infected PASDP phase 2, RSA, Zambia, Kenya and Swaziland

62.               Audit of HIV infected children PASDP phase 2, RSA, Eastern Cape.           

63.               HepCare project. Hepatitis C outreach project in collaboration with primary care.

HEPCARE EUROPE Project. Third Health Programme EU commission funded project.

UCD Medicine Research Individual Investigator

UCD Medicine Research Centre: Infectious Diseases 

Research Projects

Sponsor : HORIZON 2020
Title : HEPCARE EUROPE
Start Date / End Date : 01-MAY-16 / 30-APR-19
Sponsor : Health Services Executive (HSE)
Title : To optimise Hepatitis C diagnosis, linkage between primary, secondary and outreach community care, and access to treatment for at-risk populations (HSE Co-Funding of the EU Horizon 2020 research Project HEPCARE)
Start Date / End Date : 01-MAY-16 / 30-APR-19
Sponsor : University College Dublin (UCD)
Title : OBRSS Research Support Scheme
Start Date / End Date : 01-NOV-16 / 31-OCT-19
Sponsor : University College Dublin Foundation Ltd.
Title : Research projects
Start Date / End Date : 01-NOV-11 / 31-JUL-15
Sponsor : Janssen-Cilag Ltd.
Title : Mater HIV-ID Cohort Project - Janssen
Start Date / End Date : 01-NOV-11 / 31-DEC-13
Sponsor : GlaxoSmithKline (Ireland) Ltd.
Title : Telzir Study
Start Date / End Date : 01-DEC-08 / 28-FEB-11

Recent Postgraduates

Current Postgraduate Students

Des Crowley, Doctor of Philosophy (PhD)   -   Thesis Co-Supervisor

Teaching

Teaching Philosophy

Undergraduate Teaching experience
1.      Clinical 1 UCD Medical School Curriculum, Module Co-coordinator for ¿History and Communications¿

2.       Senior Lectures for undergraduate curriculum MMUH

3.       Haematology/Immunosuppression Module in 2008- Undergraduate Medicine Programme (Stage 4- Year 4). UCD School of Medicine and Medical Science.

4.       Therapeutics and Clinical Diagnosis Module in 2009. Lecture on Pneumonia. UCD Belfield.

5.       PUO/Tropical Medicine lecture, 30 January 2009, Senior Medical Clinic Schedule, Final Year of Medicine Curriculum, UCD.

6.       Tuberculosis lecture, 13 February 2009, Senior Medical Clinic Schedule, Final Year of Medicine Curriculum, UCD.
7.       Therapeutic Options for Developing World, Public Health Medicine, Epidemiology and International Health Module, Dec 2009, UCD.
8.       Participation in the collection, management and analysis of data for a study which has ethical approval. UCD School of Medicine and Medical Science, Research Elective MDSA 30180, SSRA 2009 Clinical Research programme
9.       Therapeutics and Clinical Diagnosis, Pneumonia, Clinical 1 Stage 4, 15 February 2010, UCD.
10.   Haematology/ Immunosuppression Module, 2008, 2009, 2010, UCD School of Medicine and Medical Science.
11.   Penang Clinical Attachments: 2010 Mater Misericordiae University Hospital.

12.   Principles & Practice of Clinical and Translational Research 2011 Course. 7th September 2011, UCD, Dublin.

 

Modules Coordinated

201700   MEDN40010     Medicine & Therapeutics: Professional Clinical Practice
     

Innovation & Leadership

2005-2011 CHIVA South Africa- Mentoring of doctors and nurses on ARV rollout for pregnant women and children with HIV. 2005-2011 Baphumelele Project- Capetown, South Africa. Support for hospice programme, consultancy for project. 2012-2013 East London- South Africa. Audit of HIV infected children Project

Collaborators

 

External Collaborators

  • Great Ormond Street Hospital,
    University College, London, UK 
  • University of Maryland at Baltimore
    Institute of Human Virology
    Medical Biotechnology Center
    725 W. Lombard Street, S-521
    Baltimore, Maryland 21201
    410-706-4601, Fax: 410-706-1992
    Email: lambert@umbi.umd.edu