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Niall Mahon

Clinical Professor

School Of Medicine
Mater Hospital
Eccles Street
Dublin 7

Tel:
Email: niall.mahon@ucd.ie

Biography

Dr Niall Mahon is Consultant Cardiologist MMUH where his practice includes interventional cardiology, cardiac device implantation, management of inherited cardiovascular conditions, and delivery of heart failure services including advanced disease requiring mechanical assist and/or heart transplantation. He is co-founder of the Mater Familiy Heart Screening Clinic, local clinical lead for the National Heart Failure Program, Chair of NCSRN, and RCPI representative on the Governance Committee for the Comparative Audit of Hospital Mortality (National Audit Office). He was co-supervisor of two MD theses submitted in 2014 and local PI for 7 ongoing international multicentre clinical studies. 

Professional

 

Associations

Association: Irish Cardiac Society, Function/Role: Fellow
Association: European Society of Cardiology, Function/Role: Fellow
Association: International Society of Heart and Lung Transplantation, Function/Role: Member
Association: International Society of Heart and Lung Transplantation Taskforce on Definitions of infection in Cardiac Transplant and Ventricular Assist Device Therapy, Function/Role: Member
Association: ESC Working Group on Myocardial and Pericardial Diseases, Function/Role: Member
Association: UK Association for Inherited Cardiovascular Conditions, Function/Role: Member
Association: UK and Ireland Transplant Cardiologists Association, Function/Role: Member
     

Conference Contributions

Mahon, N (2014) [Invited Lecture], Royal College of Psychiatrists' Annual Scientific Meeting, London , 20-NOV-14 - 20-NOV-14.
Mahon, N (2014) [Invited Lecture], 5th National Conference on Sudden Cardiac Death, Dublin , 22-NOV-14 - 22-NOV-14.
Mahon, N (2013) [Invited Lecture], Conference on Electrophysiology and Device Therapy, Cardiff , 08-FEB-13 - 09-FEB-13.
Mahon, N (2013) [Invited Lecture], Association for Inherited Cardiovascular Conditions, Cardiff , 20-NOV-13 - 20-NOV-13.
Mahon, N (2010) Advances in medical treatment of DCM and heart failure. [Invited Lecture], nnual meeting of the ESC working group on myocardial and pericardial diseases, La Coruna, Spain , 30-SEP-10 - 02-OCT-10.
Mahon, N (2010) Infectious pericarditis and myocarditis. [Chaired Session], European Society of Cardiology Annual Scientific Meeting, Stockholm , 01-SEP-10 - 01-SEP-10.
Mahon, N (2009) The role of immunoadsorption in dilated cardiomyopathy. [Invited Lecture], European Society of Cardiology Annual Scientific Meeting, Barcelona, Spain , 29-AUG-09 - 02-SEP-09.
Mahon, N (2009) Genetic causes of dilated cardiomyopathy. [Invited Lecture], UK Cardiomyopathy Association, National Medical Conference, London , 01-MAY-09 - 01-MAY-09.
Mahon, N (2009) Ventricular assist devices. [Invited Lecture], ESC, Cardiovascular Nursing nad Allied Professionals Annual Meeting, Dublin , 24-APR-09 - 25-APR-09.
Mahon, N (2007) Family screening in sudden cardiac death. [Invited Lecture], Irish Cardiac Society Annual Scientific Meeting, Belfast , 01-OCT-07 - 01-OCT-07.
Mahon, N (2006) New echocardiographic measures in DCM - Why?. [Invited Lecture], European Society for Myocardial Diseases Annual Scientific Meeting, Venice , 01-JAN-06 - 01-JAN-06.
               

Publications

     

Peer Reviewed Journals

Jones M, O'Gorman P;Kelly C;Mahon N;Fitzgibbon MC (2016) 'High-sensitive cardiac troponin-I facilitates timely detection of subclinical anthracycline-mediated cardiac injury'. Annals of Clinical Biochemistry, . [DOI] [Details]
Kane PM, Murtagh FE;Ryan K;Mahon NG;McAdam B;McQuillan R;Ellis-Smith C;Tracey C;Howley C;Raleigh C;O'Gara G;Higginson IJ;Daveson BA (2015) 'The gap between policy and practice: a systematic review of patient-centred care interventions in chronic heart failure'. Heart Failure Reviews, 20 (6):673-687. [DOI] [Details]
Moran D, Buckley A;Daly K;Meaney B;Curtin R;O'Neill JO;Colwell N;Mahon N;Murphy N;O'Hanlon R;Daly C;Mc Adam B;Mc Donald K;Maher V (2014) 'Heart rate awareness in patients with chronic stable heart failure. A multi-center observational study'. International Journal of Cardiology, 177 (2):380-384. [DOI] [Details]
Roy AK, McCullagh BN;Segurado R;McGorrian C;Keane E;Keaney J;Fitzgibbon MN;Mahon NG;Murray PT;Gaine SP (2014) 'Detection of high-sensitivity troponin in outpatients with stable pulmonary hypertension identifies a subgroup at higher risk of adverse outcomes'. Journal of Cardiac Failure, 20 (1):31-37. [DOI] [Details]
Keaney JJ, Groarke JD;Galvin Z;McGorrian C;McCann HA;Sugrue D;Keelan E;Galvin J;Blake G;Mahon NG;O'Neill J (2013) 'The Brady Bunch? New evidence for nominative determinism in patients' health: retrospective, population based cohort study'. BMJ (Clinical research ed.), 347 . [Details]
McLean S, Dhonnchu TN;Mahon N;McQuillan R;Gordijn B;Ryan K (2013) 'Left ventricular assist device withdrawal: an ethical discussion'. BMJ supportive & palliative care, . [DOI] [Details]
McGorrian C, McShane C;McQuade C;Keelan T;Neill JO;Galvin J;Malone K;Mahon NG;Codd M (2013) 'Family-based associations in measures of psychological distress and quality of life in a cardiac screening clinic for inheritable cardiac diseases: a cross-sectional study'. BMC Medical Genetics, 14 . [DOI] [Details]
Joyce E, Fabre A;Mahon N (2013) 'Hydroxychloroquine cardiotoxicity presenting as a rapidly evolving biventricular cardiomyopathy: key diagnostic features and literature review'. European Heart Journal: Acute Cardiovascular Care, 2 (1):77-83. [DOI] [Details]
Roy AK, Mc Gorrian C;Treacy C;Kavanaugh E;Brennan A;Mahon NG;Murray PT (2013) 'A Comparison of Traditional and Novel Definitions (RIFLE, AKIN, and KDIGO) of Acute Kidney Injury for the Prediction of Outcomes in Acute Decompensated Heart Failure'. CardioRenal Medicine, 3 (1):26-37. [DOI] [Details]
Groarke JD, Browne L;Margey R;McCann HA;Blake GJ;Sugrue DD;Mahon NG (2013) 'A multicentre analysis of troponin use in clinical practice'. Irish Journal of Medical Science, 182 (2):185-190. [DOI] [Details]
McGorrian C, Constant O;Harper N;O'Donnell C;Codd M;Keelan E;Green A;O'Neill J;Galvin J;Mahon NG (2013) 'Family-based cardiac screening in relatives of victims of sudden arrhythmic death syndrome'. Europace, 15 (7):1050-1058. [DOI] [Details]
Joyce E, Mulroy E;Scott J;Melling J;Goggin C;McGorrian C;O'Rourke K;Lynch T;Mahon N (2013) 'Subclinical myocardial dysfunction in multiple sclerosis patients remotely treated with mitoxantrone: evidence of persistent diastolic dysfunction'. Journal of Cardiac Failure, 19 (8):571-576. [DOI] [Details]
McGorrian CM, Lyster S;Roy A;Tarrant H;Codd M;Doran P;Fitzgibbon M;Galvin J;Mahon NG (2013) 'Use of a highly-sensitive cardiac troponin I assay in a screening population for hypertrophic cardiomyopathy: a case-referent study'. BMC Cardiovascular Disorders, 13 . [DOI] [Details]
McGorrian C, O'Hanlon R;Galvin J;Mahon NG (2013) 'Multiple myocardial clefts on cardiac magnetic resonance imaging'. Circulation, 128 (12):1388-1389. [DOI] [Details]
Horgan SJ, Margey R;Brennan DJ;O'Herlihy C;Mahon NG (2012) 'Natural history, management, and outcomes of peripartum cardiomyopathy: an Irish single-center cohort study'. Journal of Maternal-Fetal and Neonatal Medicine, 26 (2):161-165. [DOI] [Details]
Roe, MT; Armstrong, PW; Fox, KA; White, HD; Prabhakaran, D; Goodman, SG; Cornel, JH; Bhatt, DL; Clemmensen, P; Martinez, F; Ardissino, D; Nicolau, JC; Boden, WE; Gurbel, PA; Ruzullo, W; Dalby, AJ; McGuire, DK; Leiva-Pons, JL; Parkhomenko, A; Gottlieb, S; Topacio, GO; Hamm, C; Pavlides, G; Goudey, AR; Oto, A; Tseng, CD; Merkely, B; Gasparovic, V; Corbalan, R; Cinteza, M; McLendon, RC; Winters, KJ; Brown, EB; Lokhnygina, Y; Aylward, PE; Huber, K; Hochman, JS; Ohman, EM; TRILOGY ACS Investigators (2012) 'Prasrugel versus clopidogrel for acute coronary syndromes without revascularization'. New England Journal of Medicine, 367 (14):1297-1309. [Details]
Cronin EM, Mahon N;Wilkoff BL (2012) 'MRI in patients with cardiac implantable electronic devices'. Expert Review of Medical Devices, 9 (2):139-146. [DOI] [Details]
Mulroy E, Joyce E;Scott J;Melling J;Goggin C;Mahon N;O'Rourke K;Lynch T (2012) 'Long-term risk of leukaemia or cardiomyopathy after mitoxantrone therapy for multiple sclerosis'. European Neurology, 67 (1):45-47. [DOI] [Details]
Roy AK, McCarthy C;Kiernan G;McGorrian C;Keenan E;Mahon NG;Sweeney B (2012) 'Increased incidence of QT interval prolongation in a population receiving lower doses of methadone maintenance therapy'. Addiction, 107 (6):1132-1139. [DOI] [Details]
Groarke JD, Buckley U;Collison D;O'Neill J;Mahon NG;Foley B (2012) 'Cost implications of defibrillator lead failures'. Europace, 14 (8):1156-1160. [DOI] [Details]
Groarke J, Beirne A;Buckley U;O'Dwyer E;Sugrue D;Keelan T;O'Neill J;Galvin J;Mahon N (2012) 'Deficiencies in patients' comprehension of implantable cardioverter defibrillator therapy'. Pacing and clinical electrophysiology : PACE, 35 (9):1097-1102. [DOI] [Details]
Margey, R; Browne, L; Murphy, E; O'Reilly, M; Mahon, N; Blake, G; McCann, H; Sugrue, D; Galvin, J (2011) 'The Dublin cardiac registry: temporal improvement in survival from out-of-hospital cardiac arrest reflects improved pre-hospital emergency care'. Europace, 13 (8):1157-1165. [Details]
Roy, A. and Margey, R. and Mcgorrian, C. and O'donnell, C. and Nertney, L. and Mahon, N. and O'neill, J. and Keelan, T. and Galvin, J.; (2010) 'Sudden cardiac death in the young: a national registry study of the incidence and the aetiology in the republic of ireland'. EUROPEAN HEART JOURNAL, 31 (Suppl. 1):842. [Details]
Margey, R; McCann, H; Blake, G; Keelan, E; Galvin, J; Lynch, M; Mahon, N; Sugrue, D; O'Neill, J (2010) 'Contemporary management of and outcomes from cardiac device related infections'. Europace, 12 (1):64-70. [Details]
Swedberg, K; Komadja, M; Bohm, M; Borer, JS; Ford, I; Dubost-Brama, A; Lerebours, G; Tavazzi, L; SHIFT Investigators (2010) 'Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study'. Lancet, 376 (9744):875-885. [Details]
Groarke, J.D. and Blake, G. and McCann, H. and Sugrue, D. and Mahon, N. (2010) 'Increasing cardiac interventions among the aged'. Irish Medical Journal, 103 (10):308-310. [Details]
Gallagher, D. P., Kieran, J., Sheehan, G., Lambert, J., Mahon, N., Mallon, P. W. G. (2008) 'Ritonavir-boosted atazanavir, methadone, and ventricular tachycardia: 2 case reports'. Clinical Infectious Diseases, 47 (3):36-38. [Details]
O'Dwyer MJ, Mahon N;McCarthy J;Colreavey F (2008) 'The presentation of an aortic root abscess as an acute coronary syndrome'. Journal of Cardiothoracic and Vascular Anesthesia, 22 (3):446-448. [DOI] [Details]
Caforio AL, Mahon NG, Baig MK, Tona F, Murphy RT, Elliott PM, McKenna WJ. ; (2007) 'Prospective familial assessment in dilated cardiomyopathy: cardiac autoantibodies predict disease development in asymptomatic relatives'. Circulation, 115 (1):76-83. [Details]
Gallagher MM, Padula M;Sgueglia M;Santini L;Voci P;Mahon NG;Yap YG;Romeo F (2007) 'Electrocardiographic markers of structural heart disease and predictors of death in 2332 unselected patients undergoing outpatient Holter recording'. Europace, 9 (12):1203-1208. [DOI] [Details]
Healy DG, Akbar MT, Bakhtiari N, Egan JJ, Mahon N, Veerasingam D, McCarthy J, Jurley J, Neligan M, Wood AE.; (2006) 'THE FIRST 20 YEARS OF HEART TRANSPLANTATION IN IRELAND'. Irish Journal of Medical Science, 175 (1):5-9. [Details]
Caforio AL, Mahon NG, McKenna WJ. ; (2006) 'Clinical implications of anti-cardiac immunity in dilated cardiomyopathy'. Ernst Schering Research Foundation Workshop, 55 :169-193. [Details]
Matsumura Y, Elliott PM, Mahon NG, Virdee MS, Doi Y, McKenna WJ.; (2006) 'Familial dilated cardiomyopathy: assessment of left ventricular systolic and diastolic function using Doppler tissue imaging in asymptomatic relatives with left ventricular enlargement'. Heart, 92 (3):405-406. [Details]
Mahon NG, Murphy RT;MacRae CA;Caforio AL;Elliott PM;McKenna WJ (2005) 'Echocardiographic evaluation in asymptomatic relatives of patients with dilated cardiomyopathy reveals preclinical disease'. Annals of Internal Medicine, 143 (2):108-115. [Details]
Healy, DG; Lawler, Z; McEvoy, O; Parlon, B; Baktiari, N; Egan; JJ; Hurley, J; McCarthy, JF; Mahon, N; Wood, AE (2005) 'Heart transplant candidates: factors influencing waiting list mortality'. Irish Medical Journal, 98 (10):235-237. [Details]
Mahon NG, N¿¿lke L;McCann H;Sugrue D;Hurley J (2004) 'Isolated chylopericardium'. Surgeon, 1 (4):236-238. [Details]
Mahon NG, O'Neill JO;Young JB;Bennett R;Hoercher K;Banbury MK;Navia JL;Smedira NG;McCarthy PM;Starling RC (2004) 'Contemporary outcomes of outpatients referred for cardiac transplantation evaluation to a tertiary heart failure center: impact of surgical alternatives'. Journal of Cardiac Failure, 10 (4):273-278. [Details]
Varma C, O'Callaghan P;Rowland E;Mahon NG;Mckenna W;Camm AJ;Brecker SJ (2003) 'Comparison between biventricular pacing and single site pacing in patients with poor ventricular function: a hemodynamic study'. Pacing and clinical electrophysiology : PACE, 26 (2 Pt 1):551-558. [Details]
Masri K, Mahon N;Rosario A;Mirza I;Keys TF;Ratliff NB;Starling RC (2003) 'Reactive hemophagocytic syndrome associated with disseminated histoplasmosis in a heart transplant recipient'. Journal of Heart and Lung Transplantation, 22 (4):487-491. [Details]
Mahon NG, Blackstone EH;Francis GS;Starling RC;Young JB;Lauer MS (2002) 'The prognostic value of estimated creatinine clearance alongside functional capacity in ambulatory patients with chronic congestive heart failure'. Journal of the American College of Cardiology, 40 (6):1106-1113. [Details]
Varma C, O'Callaghan P;Mahon NG;Hnatkova K;McKenna W;Camm AJ;Rowland E;Brecker SJ (2002) 'Effect of multisite pacing on ventricular coordination'. Heart, 87 (4):322-328. [Details]
Mahon NG, Hedman AE;Padula M;Gang Y;Savelieva I;Waktare JE;Malik MM;Huikuri HV;McKenna WJ (2002) 'Fractal correlation properties of R-R interval dynamics in asymptomatic relatives of patients with dilated cardiomyopathy'. European Journal of Heart Failure, 4 (2):151-158. [Details]
Mahon NG, Madden BP;Caforio AL;Elliott PM;Haven AJ;Keogh BE;Davies MJ;McKenna WJ (2002) 'Immunohistologic evidence of myocardial disease in apparently healthy relatives of patients with dilated cardiomyopathy'. Journal of the American College of Cardiology, 39 (3):455-462. [Details]
Ortlepp JR, Vosberg HP;Reith S;Ohme F;Mahon NG;Schr¿¿der D;Klues HG;Hanrath P;McKenna WJ (2002) 'Genetic polymorphisms in the renin-angiotensin-aldosterone system associated with expression of left ventricular hypertrophy in hypertrophic cardiomyopathy: a study of five polymorphic genes in a family with a disease causing mutation in the myosin binding protein C gene'. Heart, 87 (3):270-275. [Details]
Mahon NG, Young JB;McKenna WJ (2002) 'Beta adrenergic blockers in chronic congestive cardiac failure: a call for action'. European Journal of Internal Medicine, 13 (2):96-100. [Details]
Monserrat L, Hermida M;Bouzas B;Mosquera I;Mahon N;Peteiro J;Alvarez N;Penas-Lado M;Crespo M;Castro-Beiras A (2002) '[Familial dilated cardiomyopathy in patients transplanted for idiopathic dilated cardiomyopathy]'. Revista espa¿¿ola de cardiolog¿¿a, 55 (7):725-732. [Details]
Caforio AL, Mahon NJ;Tona F;McKenna WJ (2002) 'Circulating cardiac autoantibodies in dilated cardiomyopathy and myocarditis: pathogenetic and clinical significance'. European Journal of Heart Failure, 4 (4):411-417. [Details]
Mahon, NG,Sugrue, DD; (1997) 'Treatment of a long segment of symptomatic myocardial bridging with multiple coronary stents'. Journal of Cardiology, 9 :484-487. [Details]
       

Editorial

Hannan, MM,Husain, S,Mattner, F,Danziger-Isakov, L,Drew, RJ,Corey, GR,Schueler, S,Holman, WL,Lawler, LP,Gordon, SM,Mahon, NG,Herre, JM,Gould, K,Montoya, JG,Padera, RF,Kormos, RL,Conte, JV,Mooney, ML; (2011) Working formulation for the standardization of definitions of infections in patients using ventricular assist devices. Editorial [DOI] [Details]
                                                                                   

Research

Research Interests

My current research interests include bio markers in cardio-oncology, urinary exosomal miRNA in stable and unstable coronary disease, frailty in heart failure and continuous haemodynamic monitoring in advanced heart failure. I am local PI for the following ongoing multi centre clinical trials.

CardioMems European Monitoring Study for Heart Failure: Mems-HF

Re-Dual PCI: Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting

COMPASS:Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

SPIRE: Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Knowledge, Attitudes and Perceptions of Implantable Cardioverter Defibrillator (ICD) Deactivation and End of Life Issues Among ICD Recipients

RELAX-HF: Efficacy, Safety and Tolerability of Serelaxin When Added to Standard Therapy in AHF

UCD Medicine Research Group: Cardiology and Cardiovascular Disease 

     

Collaborators

Internal Collaborators

Dr Joseph Galvin, MMUH and RCSI

Professor Patrick Murray, MMUH and UCD School of Medicine

Professor Catherine McGorrian, MMUH and UCD School of Medicine

Professor Maria Fitzgibbon, MMUH and UCD School of Medicine

Professor Cathy Kelly, MMUH and UCD School of Medicine

Dr John Keaney, MMUH and UCD School of Medicine

Professor Patrick Mallon, MMUH and UCD School of Medicine

External Collaborators

Professor John Ringwood, NUI Maynooth

Dr Lorenzo Monserrat, University of La Corn

Dr Alan Maisel, University of California, San Diego