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Researchers at UCD

researcher

Peter Doran

Interim Director, Ireland East Hospital Group Clin

School Of Medicine
Mater Hospital
Eccles Street
Dublin 7

Tel: +353 1 7164582
Email: peter.doran@ucd.ie

Biography

Dr. Peter Doran earned his BSc. from Dublin City University in 1998 and his PhD from University College Dublin in 2001. Dr. Doran is a lecturer at the UCD School of Medicine and Medical Science, and Scientific Director of the UCD Clinical Research Centre (CRC). The UCD CRC with facilities at both the Mater Misericordiae and St. Vincent's University Hospitals drives clinical and translational research  which is aimed at improving  patient care by acting as a catalyst to bring all members of the biomedical research entreprise together to ensure novel health interventions are developed and diffused into Irish healthcare practice.

Professional

 

Associations

Association: American Society of Hiuman Genetics, Function/Role: Member
Association: American Association for the Advancement of Science, Function/Role: Member
Association: European Association of Research Managers and Administrators , Function/Role:
       

Committees

Committee : Ethics Committee, Health Research Board
Committee : Cancer Strategy Committee, Mater Misericordiae University Hospital
Committee : Catherine MacAuley Education and Research Centre Advisory Board
Committee : University College Dublin Research Computing Steering Committee
Committee : Irish Clinical Research Infrastructure Network
Committee : EU Biological and Biomolecular Resources Infrastructure Steering Group
Committee : European Clinical Research Infrastructure Network (ECRIN) Data Management working Group
 

Education

Year 1998 Institution: Dublin City University (DCU), IRL
Qualification: BSc Subject:
Year 2001 Institution: University College Dublin
Qualification: PhD Subject:
Year 2005 Institution: Kellogg School of Management, Northwestern University
Qualification: Post Graduate Certificate Subject: Full Engagement
Year 2004 Institution: Kellogg School of Management, Northwestern University
Qualification: Post Graduate Certificate Subject: Leading High Impact Teams
Year 2002 Institution: World Intellectual Property Organisation
Qualification: Diploma Subject: Introduction to Intellectual Property
         

Publications

     

Peer Reviewed Journals

Coman, D. J.,Murray, D. W.,Byrne, J. C.,Rudd, P. M.,Bagaglia, P. M.,Doran, P. D.,Treacy, E. P.; 'Galactosemia, a single gene disorder with epigenetic consequences'. Pediatr Res, 67 (33):286-92286. Available Online [Details]
Knerr I, Coss KP;Kratzsch J;Crushell E;Clark A;Doran P;Shin Y;St¿¿ckmann H;Rudd PM;Treacy E (2015) 'Effects of temporary low-dose galactose supplements in children aged 5-12 y with classical galactosemia: a pilot study'. Pediatric Research, 78 (3):272-279. [DOI] [Details]
Ecimovic P, Murray D;Doran P;Buggy DJ (2014) 'Propofol and bupivacaine in breast cancer cell function in vitro - role of the NET1 gene'. Anticancer Research, 34 (3):1321-1331. [Details]
Coss KP, Treacy EP;Cotter EJ;Knerr I;Murray DW;Shin YS;Doran PP (2014) 'Systemic gene dysregulation in classical Galactosaemia: Is there a central mechanism?'. Molecular Genetics and Metabolism, 113 (3):177-187. [DOI] [Details]
Coss, KP,Doran, PP,Owoeye, C,Codd, MB,Hamid, N,Mayne, PD,Crushell, E,Knerr, I,Monavari, AA,Treacy, EP (2013) 'Classical Galactosaemia in Ireland: incidence, complications and outcomes of treatment'. Journal Of Inherited Metabolic Disease, 36 :21-27. [DOI] [Details]
Lahiff C, Schilling C;Cathcart MC;Mulligan N;Doran P;Muldoon C;Murray D;Pidgeon GP;Reynolds JV;Macmathuna P (2013) 'Prognostic significance of neuroepithelial transforming gene 1 in adenocarcinoma of the oesophagogastric junction'. The British journal of surgery, 101 (2):55-62. [DOI] [Details]
Ecimovic P, McHugh B;Murray D;Doran P;Buggy DJ (2013) 'Effects of sevoflurane on breast cancer cell function in vitro'. Anticancer Research, 33 (10):4255-4260. [Details]
McGorrian CM, Lyster S;Roy A;Tarrant H;Codd M;Doran P;Fitzgibbon M;Galvin J;Mahon NG (2013) 'Use of a highly-sensitive cardiac troponin I assay in a screening population for hypertrophic cardiomyopathy: a case-referent study'. BMC cardiovascular disorders, 13 . [DOI] [Details]
Lahiff C, Cotter E;Casey R;Doran P;Pidgeon G;Reynolds J;Macmathuna P;Murray D (2013) 'Expression of neuroepithelial transforming gene 1 is enhanced in oesophageal cancer and mediates an invasive tumour cell phenotype'. Journal of experimental & clinical cancer research : CR, 32 (1). [DOI] [Details]
Butler JS, Dunning EC;Murray DW;Doran PP;O'Byrne JM (2013) 'HIV-1 protein induced modulation of primary human osteoblast differentiation and function via a Wnt/¿¿-catenin-dependent mechanism'. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 31 (2):218-226. [DOI] [Details]
Knerr I, Coss KP;Doran PP;Hughes J;Wareham N;Burling K;Treacy EP (2013) 'Leptin levels in children and adults with classic galactosaemia'. JIMD reports, 9 :125-131. [DOI] [Details]
Chew, NS,Sheehan, GS,Lambert, J,McConkey, SJ,Cotter, EJ,Doran, PP,Powderly, WG (2012) 'HIV-associated osteoporosis in Ireland: prevalence and risk factors'. Future Virology, 7 :791-799. [DOI] [Details]
Cotter EJ, Chew N, Doran PP, Powderly WG; (2011) 'HIV type 1 alters Mesenchymal Stem Cell differentiation potential and phenotype ex vivo'. AIDS Research and Human Retroviruses, 27 :187-199. [Details]
Bennett G, Sadlier D, Doran PP, Macmathuna P, Murray DW; (2011) 'A functional and transcriptomic analysis of NET1 bioactivity in gastric cancer'. BMC Cancer, 11 . [DOI] [Details]
Daly M, Delaney L, Doran PP, Maclachlan M; (2011) 'The role of awakening cortisol and psychological distress in diurnal variations in affect: a day reconstruction study'. Emotion (Washington, D.C.), 11 (3):524-532. [DOI] [Details]
Ecimovic P, Murray D, Doran P, McDonald J, Lambert DG, Buggy DJ; (2011) 'Direct effect of morphine on breast cancer cell function in vitro: role of the NET1 gene'. British Journal of Anaesthesia, . [DOI] [Details]
Guerin, JS,Murray, DW,McGrath, MM,Yuille, MA,McPartlin, JM,Doran, PP; (2010) 'Molecular Medicine Ireland Guidelines for Standardized Biobanking'. Biopreservation and Biobanking, 8 :3-63. [DOI] [Details]
Coman DJ, Murray DW, Byrne JC, Rudd PM, Bagaglia PM, Doran PD, Treacy EP; (2010) 'Galactosemia, a Single Gene Disorder With Epigenetic Consequences'. Pediatric Research, 67 (3):286-292. Available Online [Details]
Lawlor G, Doran PP, MacMathuna P, Murray DW; (2010) 'MYEOV (myeloma overexpressed gene) drives colon cancer cell migration and is regulated by PGE2'. Clinical Cancer Research, 29 . [DOI] [Details]
Butler JS, Queally JM, Devitt BM, Murray DW, Doran PP, O'Byrne JM; (2010) 'Silencing Dkk1 expression rescues dexamethasone-induced suppression of primary human osteoblast differentiation'. BMC Musculoskeletal Disorders, 11 . [DOI] [Details]
Butler JS, Murray DW, Hurson CJ, O'Brien J, Doran PP, O'Byrne JM; (2010) 'The role of Dkk1 in bone mass regulation: Correlating serum Dkk1 expression with bone mineral density'. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, . [DOI] [Details]
Devitt BM, Queally JM, Vioreanu M, Butler JS, Murray D, Doran PP, O'Byrne JM; (2010) 'Cobalt ions induce chemokine secretion in a variety of systemic cell lines'. Acta Orthopaedica, 81 (6):756-764. [DOI] [Details]
Deegan CA, Murray D, Doran P, Moriarty DC, Sessler DI, Mascha E, Kavanagh BP, Buggy DJ; (2010) 'Anesthetic technique and the cytokine and matrix metalloproteinase response to primary breast cancer surgery'. Regional Anesthesia and Pain Medicine, 35 (6):490-495. [DOI] [Details]
Murphy T, Walsh PM, Doran PP, Mulhall KJ; (2010) 'Transcriptional responses in the adaptation to ischaemia-reperfusion injury: a study of the effect of ischaemic preconditioning in total knee arthroplasty patients'. Journal of translational medicine, 8 . [DOI] [Details]
Deegan CA, Murray D, Doran P, Ecimovic P, Moriarty DC, Buggy DJ.; (2009) 'Effect of anaesthetic technique on oestrogen receptor-negative breast cancer cell function in vitro'. British journal of anaesthesia, 103 (5):685-690. [Details]
Malizia, AP,Egan, JJ,Doran, PP; (2009) 'IL-4 increases CD21-dependent infection of pulmonary alveolar epithelial type II cells by EBV'. Molecular immunology, 46 (NA):1905-1910. [DOI] [Details]
O'Byrne JM, Queally JM, Devitt BM, Butler JS, Malizia AP, Murray D, Doran PP, ; (2009) 'Cobalt ions induce chemokine secretion in primary human osteoblasts'. Journal of Orthopaedic Research, (NA). [DOI] [Details]
Doran PP, Cotter EJ, Mallon PW, ; (2009) 'Is PPARgamma a Prospective Player in HIV-1-Associated Bone Disease?'. PPAR research, 2009 (NA). [DOI] [Details]
Floege J, Boor P, Eitner F, Cohen CD, Lindenmeyer MT, Mertens PR, Ostendorf T, ; (2009) 'Patients with IgA nephropathy exhibit high systemic PDGF-DD levels'. Nephrology Dialysis Transplantation, 24 (9):2755-2762. [DOI] [Details]
Doran PP, Malizia AP, Lacey N, Walls D, Egan JJ, ; (2009) 'CUX1/Wnt signaling regulates epithelial mesenchymal transition in EBV infected epithelial cells'. Experimental Cell Research, 315 (11):1819-1831. [DOI] [Details]
Powderly WG, Cotter EJ, Doran PP, ; (2009) 'Progenitor Cell Types in HIV-1 Infection; Bioactivity and Emerging Targets for Treatment'. Current HIV research, 7 (NA):508-518. [Details]
Bennett, G.Bennett, G.,Murray, D. W.Murray, D. W.,Mac Mathuna, P.Mac Mathuna, P.,Doran, P.Doran, P.; (2009) 'NET1: A Potent Promoter of Gastric Cancer - Characterisation of Gene Expression Profile Using a Novel Gene Knockdown Model'. GastroenterologyGastroenterologyGastroenterology, 136 (55). Available Online [Details]
Ecimovic, P.Ecimovic, P.,Murray, D.Murray, D.,Deegan, C.Deegan, C.,Doran, P.Doran, P.,Moriarty, D. C.Moriarty, D. C.,Buggy, D. J.Buggy, D. J.; (2009) 'Morphine Increases Breast Cancer Cell Proliferation and Migration in Vitro'. Intensive Care MedicineIntensive Care MedicineIntensive Care Medicine, 35 :60-6060. Available Online [Details]
Coman D, Murray D, Byrne JC, Rudd PM, Bagaglia P, Doran P, Treacy EP; (2009) 'Galactosemia, a single gene disorder with epigenetic consequences'. Pediatric Research, . [Details]
Buggy DJ, Deegan CA, Murray D, Doran P, Ecimovic P, Moriarty DC, ; (2009) 'Effect of anaesthetic technique on oestrogen receptor-negative breast cancer cell function in vitro'. British Journal of Anaesthesia, (NA). [DOI] [Details]
Gallego-Delgado, J,Connolly, SB,Lazaro, A,Sadlier, D,Kieran, NE,Sugrue, DD,Doran, P,Brady, HR,Osende, J,Egido, J; (2009) 'Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies'. Hypertension research : official journal of the Japanese Society of Hypertension, 32 :347-357. [DOI] [Details]
Doran P, Murray D, Horgan G, Macmathuna P, ; (2008) 'NET1-mediated RhoA activation facilitates lysophosphatidic acid-induced cell migration and invasion in gastric cancer'. British Journal of Cancer, 8 (NA):1322-1329. [DOI] [Details]
Anquetin, G., Horgan, G., Rawe, S., Murray, D., Madden, A., MacMathuna, P., Doran, P., Murphy, P. V., ; (2008) 'Synthesis of novel macrolactam and macroketone analogues of migrastatin from D-glucal and comparison with macrolactone and acyclic analogues: A dorrigocin A congener is a potent inhibitor of gastric cancer cell migration'. European Journal of Organic Chemistry, (11):1953-1958. [Details]
Egan JJ, Malizia AP, Keating DT, Smith SM, Walls D, Doran PP, ; (2008) 'Alveolar epithelial cell injury with Epstein-Barr virus upregulates TGFbeta1 expression'. Cell, 295 (3):1-60. [DOI] [Details]
Cotter, EJ,Ip, HSM,Powderly, WG,Doran, PP; (2008) 'Mechanism of HIV protein induced modulation of mesenchymal stem cell osteogenic differentiation'. Biosystems Engineering, 9 (NA):265-273. [DOI] [Details]
Keating, DTK,Malizia, AP,Sadlier, D,Hurson, C,Wood, AE,McCarthy, J,Nolke, L,Egan, JJ,Doran, PP; (2008) 'LUNG TISSUE STORAGE: OPTIMIZING CONDITIONS FOR FUTURE USE IN MOLECULAR RESEARCH'. Experimental Lung Research, 34 (NA):455-466. [DOI] [Details]
Horgan, G., Murray, D., Madden, A., Bennett, G., Anquetin, G., Murphy, P., Lennon, J., MacMathuna, P., Doran, P., ; (2008) 'Gastric cancer cell migration is reduced by novel migrastatin analogues'. Gut, 57 :23-24. [Details]
Doran P, Murray D, Horgan G, Macmathuna P, ; (2008) 'NET1-mediated RhoA activation facilitates lysophosphatidic acid-induced cell migration and invasion in gastric cancer'. Cancer, 99 (8):1322-1329. [DOI] [Details]
Malizia, A. P., Keating, D. T., Ahsan, R., Egan, J. J., Doran, P. P., ; (2008) 'A network-based analysis of epithelial-mesenchymal transition in pulmonary fibrosis'. FEBS Journal, 275 :355-355. [Details]
Horgan, G.Horgan, G.,Murray, D. W.Murray, D. W.,Madden, A.Madden, A.,Bennett, G.Bennett, G.,Ryan, J.Ryan, J.,Anquetin, G.Anquetin, G.,Paul, M. V.Paul, M. V.,MacMathuna, P.MacMathuna, P.,Doran, P.Doran, P.; (2008) 'Novel migrastatin analogues reduce gastric cancer cell migration without exhibiting cytotoxic effects'. GastroenterologyGastroenterologyGastroenterology, 134 (44). Available Online [Details]
Cotter EJ, Ip HS, Powderly WG, Doran PP; (2008) 'Mechanism of HIV protein induced modulation of mesenchymal stem cell osteogenic differentiation'. BMC musculoskeletal disorders, 9 . [DOI] [Details]
Horgan, G.Horgan, G.,Murray, D.Murray, D.,Madden, A.Madden, A.,Bennett, G.Bennett, G.,Anquetin, G.Anquetin, G.,Murphy, P.Murphy, P.,Lennon, J.Lennon, J.,MacMathuna, P.MacMathuna, P.,Doran, P.Doran, P.; (2008) 'Gastric cancer cell migration is reduced by novel migrastatin analogues'. GUTGUTGUT, 57 . Available Online [Details]
Doran, P. T.Doran, P. T.,Fritsen, C. H.Fritsen, C. H.,Murray, A. E.Murray, A. E.,Kenig, F.Kenig, F.,Mckay, C. P.Mckay, C. P.,Kyne, J. D.Kyne, J. D.; (2008) 'Entry approach into pristine ice-sealed lakes - Lake Vida, East Antarctica, a model ecosystem'. Limnology and Oceanography-MethodsLimnology and Oceanography-MethodsLimnology and Oceanography-Methods, 6 :542-547542. Available Online [Details]
Anquetin, G., Horgan, G., Rawe, S., Murray, D., Madden, A., MacMathuna, P., Doran, P., Murphy, P. V., ; (2008) 'Synthesis of novel macrolactam and macroketone analogues of migrastatin from D-glucal and comparison with macrolactone and acyclic analogues: A dorrigocin A congener is a potent inhibitor of gastric cancer cell migration'. European Journal of Organic Chemistry, (11):1953-1958. [Details]
Hurson, CJ, Butler, JS, Keating, DT, Murray, DW, Sadlier, DM, OByrne, JM, Doran, PP, ; (2007) 'Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis'. BMC Musculoskeletal Disorders, 8 . [Details]
Hurson, C. J.,Butler, J. S.,Keating, D. T.,Murray, D. W.,Sadlier, D. M.,O'Byrne, J. M.,Doran, P. P.; (2007) 'Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis'. BMC Musculoskelet Disord, 8 . [Details]
Malizia, A. P.,Vioreanu, M. H.,Doran, P. P.,Powderly, W. G.; (2007) 'HIV1 protease inhibitors selectively induce inflammatory chemokine expression in primary human osteoblasts'. Antiviral Res, 74 (1):72-6. [Details]
Malizia, A. P.,Cotter, E.,Chew, N.,Powderly, W. G.,Doran, P. P.; (2007) 'HIV protease inhibitors selectively induce gene expression alterations associated with reduced calcium deposition in primary human osteoblasts'. AIDS Res Hum Retroviruses, 23 (2):243-50. [Details]
Baelde, H. J.,Eikmans, M.,Lappin, D. W.,Doran, P. P.,Hohenadel, D.,Brinkkoetter, P. T.,van der Woude, F. J.,Waldherr, R.,Rabelink, T. J.,de Heer, E.,Bruijn, J. A.; (2007) 'Reduction of VEGF-A and CTGF expression in diabetic nephropathy is associated with podocyte loss'. Kidney Int, 71 (7):637-45. [Details]
Moss AC, Murray D, Doran P, MacMathuna P, ; (2007) 'In silico gene expression analysis--an overview'. Cancer, 6 . [DOI] [Details]
Cotter E, Chew N, Powderly WG, Doran PP. ; (2007) 'HIV proteins regulate bone marker secretion and transcription factor activity in cultured human osteoblasts with consequent potential implications for osteoblast function and development'. AIDS RESEARCH AND HUMAN RETROVIRUSES, 23 :1521-1530. [Details]
Madden A, Murray D, Murphy PV, Anquetin G, MacMathuna P and Doran P; (2007) 'Novel Migrastatin Analogues and Gastric Cancer Cell Migration'. IRISH JOURNAL OF MEDICAL SCIENCE, 176 (13). [Details]
Chew NS, Doran PP, Powderly WG; (2007) 'Osteopenia and osteoporosis in HIV: pathogenesis and treatment'. AIDS, 2 (4):318-323. [DOI] [Details]
Malizia AP, Vioreanu MH, Doran PP, Powderly WG.; (2007) 'HIV1 protease inhibitors selectively induce inflammatory chemokine expression in primary human osteoblasts'. Antiviral Res, 74 (1):72-76. [Details]
Murray, D. W.Murray, D. W.,Macmathuna, P.Macmathuna, P.,Doran, P.Doran, P.; (2007) 'Netl, a novel gastric adenocarcinoma-associated gene, drives tumor migration and invasion via cytoskeletal rearrangement events'. GastroenterologyGastroenterologyGastroenterology, 132 (44). Available Online [Details]
Murray, D.Murray, D.,Doran, P.Doran, P.,MacMathuna, P.MacMathuna, P.,Moss, A. C.Moss, A. C.; (2007) 'In silico gene expression analysis - an overview'. Molecular CancerMolecular CancerMolecular Cancer, 6 . Available Online [Details]
Moss AC, Murray D, Doran P, MacMathuna P, ; (2007) 'In silico gene expression analysis--an overview'. Cancer, 6 . [DOI] [Details]
Donoghue, P.,Doran, P.,Wynne, K.,Pedersen, K.,Dunn, M. J.,Ohlendieck, K.; (2007) 'Proteomic profiling of chronic low-frequency stimulated fast muscle'. Proteomics, 7 (18):3417-30. [Details]
Haider Y, Keating D, Lenihan R, Patricelli A, Birch M,Tomlinson A, Martin G, Ferguson MWJ, Doran PP, Egan JJ. ; (2007) 'Host predisposition by endogenous transforming growth factor B1 over expression promotes pulmonary fibrosis following exogenous injury'. Journal of Inflammation, 4 (1). [Details]
Malizia AP, Cotter E, Chew N, Powderly WG, Doran PP.; (2007) 'HIV protease inhibitors selectively induce gene expression alterations associated with reduced calcium deposition in primary human osteoblasts'. AIDS Res Hum Retroviruses, 23 (2):243-250. [Details]
Baelde, HJ,Eikmans, M,Lappin, DWP,Doran, PP,Hohenadel, D,Brinkkoetter, PT,van der Woude, FJ,Waldherr, R,Rabelink, TJ,de Heer, E,Bruijin, JA; (2007) 'Reduction of VEGF-A and CTGF expression in diabetic nephropathy is associated with podocyte loss'. Kidney International, 71 :637-645. [DOI] [Details]
Malizia, AP; Cotter, EC; Powderly, WG; Doran, PP; ; (2006) 'HIV-1 protease inhibitors selectively induce gene expression alterations associated with reduced calcium deposition in primary human osteoblasts'. Antiviral Therapy, 11 (7):62-62. [Details]
Keating, DT; Sadlier, DM; Patricelli, A; Smith, SM; Walls, D; Egan, JJ; Doran, PP; ; (2006) 'Microarray identifies ADAM family members as key responders to TGF-beta 1 in alveolar epithelial cells'. Respiratory Research, 7 (NA). [Details]
Leyden, J., Murray, D., Moss, A., Arumuguma, M., Doyle, E., McEntee, G., O'Keane, C., Doran, P MacMathuna, P.; (2006) 'Net1 and Myeov: computationally identified mediators of gastric cancer'. BRITISH JOURNAL OF CANCER, 94 (8):1204-1212. [Details]
Moss AC and Lawlor G, Murray D, Tighe D, Madden SF, Mulligan AM, Keane CO, Brady HR, Doran PP and MacMathuna P ; (2006) 'ETV4 and Myeov knockdown impairs colon cancer cell line proliferation and invasion'. Biochemical and biophysical research communications, 345 (1):216-221. [DOI] [Details]
Leyden, J; Murray, D; Moss, A; Arumuguma, M; Doyle, E; McEntee, G; O'Keane, C; Doran, P; MacMathuna, P; ; (2006) 'Net1 and Myeov: computationally identified mediators of gastric cancer'. British Journal of Cancer, 94 (8):1204-1212. [Details]
Keating, DT; Sadlier, DM; Patricelli, A; Smith, SM; Walls, D; Egan, JJ; Doran, PP; ; (2006) 'Microarray identifies ADAM family members as key responders to TGF-beta 1 in alveolar epithelial cells'. Respiratory Research, 7 (NA). [Details]
Malizia, AP; Cotter, EC; Powderly, WG; Doran, PP; ; (2006) 'HIV-1 protease inhibitors selectively induce gene expression alterations associated with reduced calcium deposition in primary human osteoblasts'. Antiviral Therapy, 11 (7):62-62. [Details]
Cotter, EJ; Chew, N; Powderly, WG; Doran, PP; Malizia, AP; ; (2006) 'Modification of transcriptional activity and regulation drives osteoblast response to HIV and its treatment in vitro'. Antiviral Therapy, 11 (7):9-9. [Details]
Vioreanu, MH; Patricelli, A; Doran, PP; Powderly, WG; O'Byrne, JM; ; (2006) 'HIV1 protease inhibitors selectively induce inflamatory chemokine expression in primary human ostopblasts: A novel mechanism of osteoporosis in treated HIV plus patients'. Journal of Bone and Mineral Research, 21 (7):1168-1168. [Details]
Moss, A. C.,Lawlor, G.,Murray, D.,Tighe, D.,Madden, S. F.,Mulligan, A. M.,Keane, C. O.,Brady, H. R.,Doran, P. P.,MacMathuna, P.; (2006) 'ETV4 and Myeov knockdown impairs colon cancer cell line proliferation and invasion'. Biochem Biophys Res Commun, 345 (1):216-21. [Details]
Butler, J. S.Butler, J. S.,Hurson, C.Hurson, C.,Murray, D.Murray, D.,Sadlier, D.Sadlier, D.,O'Byrne, J. M.O'Byrne, J. M.,Doran, P. P.Doran, P. P.; (2006) 'Altered developmental pathways as novel drivers of osteoporosis in primary human osteoblasts'. Osteoporosis InternationalOsteoporosis InternationalOsteoporosis International, 17 . Available Online [Details]
Lowlor, G.Lowlor, G.,Moss, A.Moss, A.,Tighe, D.Tighe, D.,Murray, D. W.Murray, D. W.,O'Keane, C.O'Keane, C.,Doran, P.Doran, P.,MacMathuna, P.MacMathuna, P.; (2006) 'Functional significance of enhanced ETV4 and MYEOV expression in colorectal neoplasia using sirna-mediated gene knockdown'. GastroenterologyGastroenterologyGastroenterology, 130 (44). Available Online [Details]
Murray, D. W.Murray, D. W.,Leyden, J.Leyden, J.,McEntee, G.McEntee, G.,O'Keane, C.O'Keane, C.,MacMathuna, P.MacMathuna, P.,Doran, P.Doran, P.; (2006) 'NET1 - A novel activator of RhoA and gastric cancer cell invasion'. GastroenterologyGastroenterologyGastroenterology, 130 (44). Available Online [Details]
Keating DT, Sadlier D, Linehan R, Patricelli A, Smith S, Walls D, Egan JJ, Doran P. ; (2006) 'Microarray gene profiling identifies ADAM family members as key mediators of pulmonary fibrosis'. Respiratory Research, 7 . [Details]
Leyden, J; Murray, D; Moss, A; Arumuguma, M; Doyle, E; McEntee, G; O'Keane, C; Doran, P; MacMathuna, P; ; (2006) 'Net1 and Myeov: computationally identified mediators of gastric cancer'. British Journal of Cancer, 94 (8):1204-1212. [Details]
Keating, DT,Sadlier, DM,Patricelli, A,Smith, SM,Walls, D,Egan, JJ,Doran, PP; (2006) 'Microarray identifies ADAM family members as key responders to TGF-beta 1 in alveolar epithelial cells'. Respiratory Research, 7 . [DOI] [Details]
Murray, D and Leyden, J, Moss, A, Arumuguma, M, Doyle, E, McEntee, G, O'Keane, C, Doran, P and MacMathuna, P, ; (2006) 'Net1 and Myeov: computationally identified mediators of gastric cancer'. BRITISH JOURNAL OF CANCER, 94 (8):1204-1212. [DOI] [Details]
Cotter, EJ; Chew, N; Powderly, WG; Doran, PP; Malizia, AP; ; (2006) 'Modification of transcriptional activity and regulation drives osteoblast response to HIV and its treatment in vitro'. Antiviral Therapy, 11 (7):9-9. [Details]
Vioreanu, MH; Patricelli, A; Doran, PP; Powderly, WG; O'Byrne, JM; ; (2006) 'HIV1 protease inhibitors selectively induce inflamatory chemokine expression in primary human ostopblasts: A novel mechanism of osteoporosis in treated HIV plus patients'. Journal of Bone and Mineral Research, 21 (7):1168-1168. [Details]
Patricelli, A; Doran, PP; Powderly, W; ; (2005) 'Protease inhibitors selectively induce chemokine expression in human osteoblasts'. Antiviral Therapy, 10 (8):51-51. [Details]
Yasuda, Y; Schmid, H; Boucherot, A; Eichinger, F; Brunner, B; Sadlier, DM; Henger, A; Nitsche, A; Bleich, M; Cohen, CD; Doran, P; Brady, HR; Groene, HJ; Schloendorff, D; Nelson, PJ; Kretzler, M; ; (2005) 'Genome-wide transcriptomic analysis identifies gene expression signature of NF-kappa B pathway activation in progressive human diabetic nephropathy'. Nephrology Dialysis Transplantation, 20 (NA):371-371. [Details]
Cohen, CD; Doran, PP; Blattner, SM; Merkle, M; Wang, GQ; Schmid, H; Mathieson, PW; Saleem, MA; Henger, A; Rastaldi, MP; Kretzler, M; ; (2005) 'Sam68-like mammalian protein 2, identified by digital differential display as expressed by podocytes, is induced in proteinuria and involved in splice site selection of vascular endothelial growth factor'. Journal of the American Society of Nephrology, 16 (7):1958-1965. [Details]
Egan JJ, Doran P, ; (2005) 'Herpesviruses: a cofactor in the pathogenesis of idiopathic pulmonary fibrosis?'. Cell, 289 (5):1-10. [DOI] [Details]
Leyden, J.Leyden, J.,Murray, D.Murray, D.,Alan, M.Alan, M.,Arumaguma, M.Arumaguma, M.,Doyle, E.Doyle, E.,McEntee, G.McEntee, G.,O'Keane, C.O'Keane, C.,Doran, P.Doran, P.,MacMatnuna, P.MacMatnuna, P.; (2005) 'Novel gastric cancer associated genes identified using digital differential display'. GastroenterologyGastroenterologyGastroenterology, 128 (44). Available Online [Details]
Sadlier, D. M.Sadlier, D. M.,Ouyang, X.Ouyang, X.,McMahon, B.McMahon, B.,Mu, W.Mu, W.,Ohashi, R.Ohashi, R.,Rodgers, K.Rodgers, K.,Murray, D.Murray, D.,Nakagawa, T.Nakagawa, T.,Godson, C.Godson, C.,Doran, P.Doran, P.,Brady, H. R.Brady, H. R.,Johnson, R. J.Johnson, R. J.; (2005) 'Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis'. Kidney InternationalKidney InternationalKidney International, 68 (66):2542-25612542. Available Online [Details]
Dolan, V.,Murphy, M.,Sadlier, D.,Lappin, D.,Doran, P.,Godson, C.,Martin, F.,O'Meara, Y.,Schmid, H.,Henger, A.,Kretzler, M.,Droguett, A.,Mezzano, S.,Brady, H. R.; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. Am J Kidney Dis, 45 (6):1034-9. [Details]
Sadlier, DM; Ouyang, X; McMahon, B; Mu, W; Ohashi, R; Rodgers, K; Murray, D; Nakagawa, T; Godson, C; Doran, P; Brady, HR; Johnson, RJ; ; (2005) 'Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis'. Kidney International, 68 (6):2542-2561. [Details]
Patricelli, A; Doran, PP; Powderly, WG; ; (2005) 'Exogenous HIV-1 proteins induce alterations in differentiation and modulation of HIV-1 receptors in primary human mesenchymal stem cells'. Antiviral Therapy, 10 (8):13-14. [Details]
Dolan, V; Murphy, M; Sadlier, D; Lappin, D; Doran, P; Godson, C; Martin, F; O'Meara, Y; Schmid, H; Henger, A; Kretzler, M; Droguett, A; Mezzano, S; Brady, HR; ; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. American Journal of Kidney Diseases, 45 (6):1034-1039. [Details]
Dolan, V; Murphy, M; Sadlier, D; Lappin, D; Doran, P; Godson, C; Martin, F; O'Meara, Y; Schmid, H; Henger, A; Kretzler, M; Droguett, A; Mezzano, S; Brady, HR; ; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. American Journal of Kidney Diseases, 45 (6):1034-1039. [Details]
Baelde, HJ; Eikmans, M; Doran, PP; Lappin, DWP; de Heer, E; Bruijn, JA; ; (2004) 'Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy'. American Journal of Kidney Diseases, 43 (4):636-650. [Details]
Keating, DT; Sadlier, D; Hurson, C; Doran, P; Egan, JJ; ; (2004) 'Oligonucleotide microarray analysis reveals coordinated expression of extracellular matrix associated genes in pulmonary fibrosis in vitro'. Thorax, 59 (1):42-42. [Details]
Shahbazi, RI; McCann, A; Frawley, A; Doran, P; Chung, WY; Dervan, P; Kerin, MJ; ; (2004) 'Validation of gamma-actin as a potential target in breast cancer'. British Journal of Surgery, 91 (9):1216-1216. [Details]
Henger, A; Kretzler, M; Doran, P; Bonrouhi, M; Schmid, H; Kiss, E; Cohen, CD; Madden, S; Porubsky, S; Grone, EF; Schlondorff, D; Nelson, PJ; Grone, HJ; ; (2004) 'Gene expression fingerprints in human tubulointerstitial inflammation and fibrosis as prognostic markers of disease progression'. Kidney International, 65 (3):904-917. [Details]
Conway, B. R.,Maxwell, A. P.,Savage, D. A.,Patterson, C. C.,Doran, P. P.,Murphy, M.,Brady, H. R.,Fogarty, D. G.; (2004) 'Association between variation in the actin-binding gene caldesmon and diabetic nephropathy in type 1 diabetes'. Diabetes, 53 (4):1162-5. [Details]
Sadlier, D. M.,Connolly, S. B.,Kieran, N. E.,Roxburgh, S.,Brazil, D. P.,Kairaitis, L.,Wang, Y.,Harris, D. C.,Doran, P.,Brady, H. R.; (2004) 'Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy'. J Biol Chem, 279 (28):29670-80. [Details]
Baelde, HJ; Eikmans, M; Lappin, DWP; Doran, PP; Brady, H; De Heer, E; Bruijn, JA; ; (2003) 'Renal cortical and glomerular mRNA for VEGF is decreased but that for TGF-beta is unaltered in human diabetic nephropathy'. Journal of the American Society of Nephrology, 14 (NA):127-127. [Details]
Chang, B; Madden, S; Doran, P; Kane, R; O'Brien, C; ; (2003) 'In silico gene identification of eye specific genes'. Investigative Ophthalmology &Amp; Visual Science, 44 (NA):81-81. [Details]
Moynihan, BJ; Madden, S; Duggan, J; Doran, P; Brady, HR; ; (2003) 'Digital differential display: A novel tool for. investigating transcriptomic changes in fibroblasts in fibrotic renal-disease'. Journal of the American Society of Nephrology, 14 (NA):891-891. [Details]
Sadlier, DM; Frawley, A; Doran, P; Brady, HR; ; (2003) 'Comparison of bioinformatic techniques for analysis of microarray generated datasets reveals algorithm dependent conclusions regarding quantitative gene expression'. Journal of the American Society of Nephrology, 14 (NA):23-23. [Details]
Connolly, SB; Sadlier, D; Kieran, NE; Doran, P; Brady, HR; ; (2003) 'Transcriptome profiling and the pathogenesis of diabetic complications'. Journal of the American Society of Nephrology, 14 (NA):279-283. [Details]
Connolly, S. B.,Sadlier, D.,Kieran, N. E.,Doran, P.,Brady, H. R.; (2003) 'Transcriptome profiling and the pathogenesis of diabetic complications'. J Am Soc Nephrol, 14 (8 Suppl 3):S279-83. [Details]
Sadlier, DM; Brazil, D; Doran, P; Brady, HR; ; (2003) 'Microarray and bioinformatic analysis identified common patterns of matrix gene expression in glomerular injury dependent and independent models of tubulo-interstitial fibrosis in vivo'. Journal of the American Society of Nephrology, 14 (NA):366-366. [Details]
Kieran, NE; Doran, PP; Connolly, SB; Greenan, MC; Higgins, DF; Leonard, M; Godson, C; Taylor, CT; Henger, A; Kretzler, M; Burne, MJ; Rabb, H; Brady, HR; ; (2003) 'Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog'. Kidney International, 64 (2):480-492. [Details]
Madden, SF; O'Donovan, B; Furney, SJ; Brady, HR; Silvestre, G; Doran, PP; ; (2003) 'Digital extractor: analysis of digital differential display output'. Bioinformatics, 19 (12):1594-1595. [Details]
Madden, SF; Lappin, DWP; Murphy, MM; Martin, FM; Eikmans, M; De Heer, E; Baelde, H; Brady, HR; Doran, PP; ; (2002) 'Computational gene annotation in diabetic nephropathy'. Journal of the American Society of Nephrology, 13 (NA):118-118. [Details]
Lappin, DWP; Mullally, A; Kairaitis, L; Wang, YP; Godson, C; Harris, DCH; Brady, HR; Doran, PP; ; (2002) 'Temporal patterns of gene expression in adriamycin-induced nephrosis'. Journal of the American Society of Nephrology, 13 (NA):117-117. [Details]
Madden, SF; Lappin, DWP; Murphy, MM; Martin, FM; Eikmans, M; De Heer, E; Baelde, H; Brady, HR; Doran, PP; ; (2002) 'Computational gene annotation in diabetic nephropathy'. Journal of the American Society of Nephrology, 13 (NA):118-118. [Details]
Furney, SJ; Madden, SF; Brady, HR; Doran, PP; ; (2002) 'Digital extractor: Software for the analysis of digital differential display output'. Journal of the American Society of Nephrology, 13 (NA):122-122. [Details]
Baelde, HJJ; Eikmans, M; Brady, HR; Lappin, DWP; Doran, PP; De Heer, E; Bruijn, JA; ; (2002) 'Gene expression profiling in cortical and glomerular tissue from human diabetic kidneys'. Journal of the American Society of Nephrology, 13 (NA):121-121. [Details]
Henger, A; Kretzler, M; Doran, P; Madden, S; Grone, E; Schlondorff, D; Nelson, PJ; Grone, HJ; ; (2002) 'Gene expression fingerprints in human tubulo-interstitial inflammation and fibrosis'. Journal of the American Society of Nephrology, 13 (NA):474-474. [Details]
Lappin, DWP; Higgins, D; Madden, SF; Moriyama, T; Imai, E; Doran, PP; Brady, HR; ; (2002) 'Deciphering the renal transcriptome in response to diabetes mellitus'. Journal of the American Society of Nephrology, 13 (NA):124-124. [Details]
Kretzler, M; Cohen, CD; Doran, P; Henger, A; Madden, S; Grone, EF; Nelson, PJ; Schlondorff, D; Grone, HJ; ; (2002) 'Repuncturing the renal biopsy: Strategies for molecular diagnosis in nephrology'. Journal of the American Society of Nephrology, 13 (7):1961-1972. [Details]
Lappin, DWP; Mullally, A; Kairaitis, L; Wang, YP; Godson, C; Harris, DCH; Brady, HR; Doran, PP; ; (2002) 'Temporal patterns of gene expression in adriamycin-induced nephrosis'. Journal of the American Society of Nephrology, 13 (NA):117-117. [Details]
Kieran, NE; Connolly, SB; Greenan, MC; Higgins, D; Burne, MJ; Godson, C; Doran, PP; Rabb, H; Brady, HR; ; (2002) 'The transcriptomic response to renal ischemia-reperfusion injury and its modification by lipoxin A4 analogue FphO-15-RLXA4-Me'. Journal of the American Society of Nephrology, 13 (NA):120-120. [Details]
Lappin, DWP; Doran, P; Godson, C; Brady, HR; ; (2002) 'Gene responses to hyperglycaemia'. Experimental Nephrology, 10 (2):120-129. [Details]
Leonard MO, Hannan K, Burne MJ, Lappin DW, Doran P, Coleman P, Stenson C, Taylor CT, Daniels F, Godson C, Petasis NA, Rabb H, Brady HR.; (2002) '15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure'. Journal of the American Society of Nephrology, 13 (6):1657-1662. [Details]
Diamond, P.,Doran, P.,Brady, H. R.,McGinty, A.; (2000) 'Suppressors of cytokine signalling (SOCS): putative modulators of cytokine bioactivity in health and disease'. J Nephrol, 13 (1):9-14. [Details]

Other Journals

Chew NS, Doran PP, Powderly WG. ; (2007) 'Osteopenia and osteoporosis in HIV and AIDS: pathogenesis and treatment' Current Opinion in HIV and AIDS 2 :318-323. [Details]
Doran, P. Egan, J. J.; (2005) 'Herpesviruses: a cofactor in the pathogenesis of idiopathic pulmonary fibrosis?' Editorial Focus . [Details]

Conference Publications

Horgan H, Murray D, Madden A, Bennett B, Anquetin G, Murphy P, Lennon J, MacMathuna P and Doran P; (2008) Gastric Cancer Cell Migration Is Reduced By Novel Migrastatin Analogues British Gastroenterology Meeting [Details]
Horgan G, Murray DW, Madden A, Bennett G, Ryan J, Anquetin G, Murphy PV, MacMathuna P and Doran P ; (2008) Novel Migrastatin Analogues Reduce Gastric Cancer Cell Migration Without Exhibiting Cytotoxic Effects American Gastroenterological Association : Digestive Disease Week [Details]
Butler, J. S., Doran, P. P., Moon, R. T., O'Byme, J. M., Powderly, W. G., ; (2007) Journal of Bone and Mineral Research Aberrations in Wnt/beta-catenin signaling driving HAART-induced bone loss in vitro , pp.219-219 [Details]
Murray DW, MacMathuna P and Doran P ; (2007) Netl, a novel gastric adenocarcinoma-associated gene, drives tumor migration and invasion via cytoskeletal rearrangement events AGA DDW 07 [Details]
Doran PP, Malizia AP, Cotter E, Chew N, Powderly WG, ; (2007) AIDS research and human retroviruses HIV protease inhibitors selectively induce gene expression alterations associated with reduced calcium deposition in primary human osteoblasts , pp.243-250 [DOI] [Details]
Lawlor, G., Moss, A., Tighe, D., Murray, D., Madden, S., Mulligan, AM., O'Keane, C., Brady, H., Doran, P. MacMathuna, P.; (2006) Functional Significance of Enhanced Etv4 and Myeov Expression in Colorectal Neoplasia using siRNA-Mediated Gene Knockdown The Irish Association for Cancer Research Annual Meeting [Details]
Lawlor, G., Tighe, T.G., Moss, A., Murray, D., Madden, S., Mulligan, A.M., O'Keane, C., Brady, H., Doran, P. MacMathuna, P.; (2006) Functional Significance of Enhanced Etv4 and Myeov Expression in Colorectal Neoplasia using siRNA-Mediated Gene Knockdown Mater Misericordiae University Hospital - Young Investigators Research Symposium [Details]
Lawlor, G., Murray, D, Moss, A., Leyden, J., Sadlier, D., O' Keane, C., Mulligan, AM., Arumuguma, M., Doyle, E., McEntee, G., MacMathuna, P. Doran, P.; (2006) Gastrointestinal Epithelial Cancers ' A Common Gene Expression Profile? The Irish Association for Cancer Research Annual Meeting [Details]
Ahsan, M., Keating, D., Healy, D., Nolke, L., McCarthy, J., Wood, F., Doran, P. Egan, J.; (2006) Microarray identifies developmental genes expression in small airway epithelial cells following TGF-b1 stimulation International Society for Heart & Lung Transplantation, 26th Annual Meeting & Scientific Session [Details]
Murray, D., Leyden, J., Arumuguma, M., Doyle, E., McEntee, G., O'Keane, C., MacMathuna, P. Doran, P.; (2006) NET1 - a novel activator of gastric tumor cell invasion and RhoA The American Association for Cancer Research 97th Annual Meeting [Details]
Murray, D., Leyden, J., Arumuguma, M., Doyle, E., McEntee, G., O'Keane, C., MacMathuna, P. Doran, P.; (2006) NET1 - A Novel Activator of RhoA and Gastric Cancer Cell Invasion Mater Misericordiae University Hospital - Young Investigators Research Symposium [Details]
O'Brien, J., Doran, P. Eustace, S.; (2006) The use of Whole-body MRI for body fat assessment and comparison with serum leptin concentration. (Poster presentation) European Society Of Skeletal Radiology [Details]
O'Brien, J., McMahon, P., Eustqace, S. Doran, P.; (2006) A Comparison of red marrow volume determined at Whole-body MRI, with DEXA derived bone density and serum cytokine levels RCSI [Details]
Patricelli, A., Keating, D.T., Smith, S., Walls, D., Wood, A.E., Doran, P.P. Egan, J.J.; (2006) Alveolar epithelial cell infection with EBv upregulates TGFb1 expression American Thoracic Society International Conference [Details]
O'Brien, J., Doran, P. Eustace, S.; (2006) Whole Body MRI for total body fat assessment : Correlation with serum protein regulators of fat metabolism Spring Meeting Faculty of Radiology [Details]
Lawlor, G., Moss, A., Tighe, D., Murray, D., Madden, S., Mulligan, A.M., O'Keane, C., Brady, H., Doran, P. Mac Mathuna, P.; (2006) Functional Significance of enhanced ETV4 and Myeov Expression in Colorectal Neoplasia using Si-Mediated Gene Knockdown Digestive Diseases Week [Details]
O'Brien, J, Shelly, M., McMahon, P., Doran, P. Eustace, S.; (2006) Evaluation of Marrow volume on Whole-Body MRI and subsequent comparison with bone density and serum cytokines European Society Of Skeletal Radiology [Details]
Patricelli, A., Keating, D.T., Smith, S., Walls, D., Wood, A.E., Doran, P.P. Egan, J.J.; (2006) Early role of EBV infection during epithelial cell transition to fibroblasts in human alveolar epithelial cells American Thoracic Society International Conference [Details]
Murray DW, Leyden J, Arumuguma M, Doyle E, McEntee G, O'Keane C, MacMathuna P, Doran P. ; (2006) NET1 - a novel activator of gastric tumour cell invasion and RhoA American Association for Cancer Research Annual Meeting [Details]
Murray DW, Leyden J, McEntee G, O'Keane C, MacMathuna P and Doran P ; (2006) NET1 - A novel activator of RhoA and gastric cancer cell invasion AGA DDW [Details]
Lowlor G, Moss A, Tighe D, Murray DW, O'Keane C, Doran P and MacMathuna P ; (2006) Functional significance of enhanced ETV4 and MYEOV expression in colorectal neoplasia using sirna-mediated gene knockdown AGA DDW [Details]
Murray, D., Leyden, J., Arumuguma, M., Doyle, E., McEntee, G., O'Keane, C., MacMathuna, P. Doran, P.; (2006) NET1 - A Novel Activator of RhoA and Gastric Cancer Cell Invasion The Irish Association for Cancer Research Annual Meeting [Details]
Keating, D.T., Sadlier, D.M., Patricelli, A., Smith, S.M., Walls, D., Egan, J.J Doran, P.P.; (2005) Computational transcriptome annotation; A powerful strategy in respiratory research American Thoracic Society [Details]
Patricelli, A., Keating, D.T., Smith, S., Walls, D., Wood, A.E., Doran, P.P. Egan, J.J.; (2005) Early role of EBV infection during epithelial cell transition to fibroblasts in human alveolar epithelial cells Understanding the Genome, Microarray applications from the biology to the clinic [Details]
Patricelli, A., Doran, P.P. Powderly, W.G.; (2005) Exogenous HIV-1 proteins induce alterations in differentiation and modulation of HIV-1 receptors in primary human mesenchymal stem cells Adverse drug Reactions and Lipodystrophy in HIV , 13-NOV-05 - 17-NOV-05 [Details]
Lawlor, G., Moss, A., Tighe, D., Murray, D., Madden, S., Mulligan, A.M., O'Keane, C., Brady, H., Doran, P. Mac Mathuna, P.; (2005) Functional Significance of Enhanced ETV4 and Myeov expression in Colorectal Neoplasia Irish Society of Gastroenterology [Details]
Keating, D.T., Sadlier, D.M., Patricelli, A., Smith, S.M., Walls, D., Egan, J.J Doran, P.P.; (2005) Analysis of oligonucleotide microarray reveals coordinated expression of extracellular matrix associated genes in an in vitro model of pulmonary fibrosis American Thoracic Society [Details]
Keating, D.T., Sadlier, D., Linehan, R., Patricelli, A., Smith, S.M., Walls , D., Doran, P. Egan, J.J.; (2005) Microarrays reveal co-ordinated expression of ADAMs family of genes in an in vitro model of pulmonary fibrosis European respiratory society [Details]
Murray, D., Leyden, J., Arumuguma, M., Doyle, E., McEntee, G., O'Keane, C., MacMathuna, P. Doran, P.; (2005) NET1 - A Novel Activator of RhoA and Gastric Tumour Cell Invasion The Irish Society of Gastroenterology Annual Meeting [Details]
Patricelli, A., Doran, P.P. Powderly, W.G.; (2005) Protease inhibitors selectively induce chemokine expression in human osteoblasts Adverse drug Reactions and Lipodystrophy in HIV , 13-NOV-05 - 17-NOV-05 [Details]
Patricelli, A., Doran, P.P. Powderly, W.G.; (2005) Protease inhibitors selectively induce gene expression alterations associated with reduced calcium deposition in primary human osteoblasts Understanding the Genome, Microarray applications from the biology to the clinic , 11-NOV-05 - 13-NOV-05 [Details]
Keating, D.T., Sadlier, D.M., Patricelli, A., Smith, S.M., Walls, D., Egan, J.J Doran, P.P.; (2005) Growth factor expression in pulmonary fibrosis; a genome wide view American Thoracic Society [Details]

Published Reports

Doran et al; (2009) Genelibrary Ireland-Design Phase. Molecular Medicine Ireland, dublin. Available Online [Details]
 

Editorial

Doran, P,Egan, JJ; (2005) Herpesviruses: a cofactor in the pathogenesis of idiopathic pulmonary fibrosis?. Editorial [DOI] [Details]
                 

Abstract

Barry S, Fattah C, Farah N, Stuart B, Doran P, Murray D, Turner MJ. ; (2009) Can maternal Bioelectrical Impedance Analysis (BIA) predict birth weight?. Abstract [Details]
                                                               

Research

Research Interests

The main focus of my research is the complications associated with HIV and its treatment. Since the introduction of Highly Active Antiretroviral Therapy (HAART), morbidity and mortality have been significantly reduced. However, a number of serious side effects have been seen in these patients.  HIV patients are at increased risk of decreased bone density, and osteoporosis. Our laboratory research is focused on uncovering the effects of both HIV and antiviral treatment on the biology of bone cells. Specifically we are interested in changes in the function of osteoblasts and Mesesnchymal stem cells. Through these investigations we are gaining frther insight into the interaction of HIV with the body.

 

Research Projects

Sponsor : Irish Cancer Society (ICS)
Title : Integrating biomarkers for the stratification of patients into insignificant and significant prostate cancer
Start Date / End Date : 01-OCT-11 / 31-MAY-15
Sponsor : Health Research Board (HRB)
Title : Prospective Validation of Acute Kidney Injury Biomarkers in Critically Ill Patients
Start Date / End Date : 01-OCT-11 / 01-OCT-14
Sponsor : University College Dublin (UCD)
Title : School Funded Research Account
Start Date / End Date : 01-NOV-14 / 31-DEC-19
Sponsor : Health Research Board (HRB)
Title : Dublin Centre for Clinical Research
Start Date / End Date : 01-MAR-08 / 31-DEC-14
Sponsor : University College Dublin (UCD)
Title : Agilent 2100 bioanalyzer for the UCD Clinical Research
Start Date / End Date : 26-MAY-08 / 01-DEC-09
Sponsor : European Commission FP5
Title : Common Moleculum Pathways in Progression of Kidney Disease
Start Date / End Date : 01-OCT-02 / 30-SEP-05
Sponsor : Internal Transfer
Title : Mater Hospital Genome Resource Unit
Start Date / End Date : 01-JAN-06 / 31-DEC-07