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Tapesh Santra

Postdoc Research Fellow Lvl Ii

School Of Medicine
Conway Institute
Belfield
Dublin 4

Tel: +353 1 7166831
Email: tapesh.santra@ucd.ie

Biography

I received my PhD from the Department of Computing Science, Glasgow University, Scotland U.K. in 2011. My PhD thesis was about generalizing the theory of nonlinear dynamic systems for arbitrarily large networks and applying  this theory to understand the evolution of biochemical networks in yeast. 

 I am currently working as a Post Doctoral Researcher in Systems Biology Ireland, U.C.D. under the supervision of Prof. Boris Kholodenko and Prof. Walter Kolch. My current work is focused on developing statistical techniques for inferring network topology from biological data. My research interest is in Mathematical and Statistical modeling of biochemical pathways.

Publications

     

Peer Reviewed Journals

Bastiaens, P. and Birtwistle, M.R. and Blüthgen, N. and Bruggeman, F.J. and Cho, K.-H. and Cosentino, C. and De La Fuente, A. and Hoek, J.B. and Kiyatkin, A. and Klamt, S. and Kolch, W. and Legewie, S. and Mendes, P. and Naka, T. and Santra, T. and Sontag, E. and Westerhoff, H.V. and Kholodenko, B.N. (2015) 'Silence on the relevant literature and errors in implementation'. Nature Biotechnology, 33 (4):336-339. Available Online [DOI] [Details]
Brown JA, Santra T;Owens P;Morrison AM;Barry F (2014) 'Primary cilium-associated genes mediate bone marrow stromal cell response to hypoxia'. Stem cell research, 13 (2):284-299. [DOI] [Details]
Santra, T. and Kolch, W. and Kholodenko, B.N. (2014) 'Navigating the Multilayered Organization of Eukaryotic Signaling: A New Trend in Data Integration'. PLoS Computational Biology, 10 (2). Available Online [DOI] [Details]
Santra T, Kolch W, Kholodenko BN (2013) 'Integrating Bayesian variable selection with Modular Response Analysis to infer biochemical network topology'. BMC systems biology, 7 . [DOI] Link to full text [Details]
Santra T, Kholodenko B, Kolch W (2012) 'An integrated Bayesian framework for identifying phosphorylation networks in stimulated cells'. Frontiers in Modeling and Control of Breathing, 736 :59-80. [DOI] Link to full text [Details]
                                                                                 

Published abstracts

Halasz, M; Santra, T; Rodriguez, J; Kholodenko, B; Kolch W (2014) Proteomic profiling of N-Myc-associated proteins in neuroblastoma. Published abstracts [Details]
         

Research

Research Interests

I am interested in mathematical and statistical modeling of biochemical pathways. I am currently developing statistical algorithms for inferring network topology from biological data.