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Researchers at UCD

Douglas Veale

Adjunct Professor

School Of Medicine
St Vincent's Hospital
Elm Park
Dublin 4

Tel:
Email: douglas.veale@ucd.ie

Biography

Douglas J. Veale is Director of Translational Research of the DAMC, Professor of Medicine and Consultant Rheumatologist at St Vincent's University Hospital and a Principal Investigator at The Conway Institute for Biomedical and Biomolecular Research, University College Dublin (UCD). He is a Fellow of both the Royal College of Physicians in Ireland (1997) and the Royal College, London (1999).  Professor Veale graduated from the Royal College of Surgeons in Ireland in 1984 and obtained his MD by thesis from UCD in 1992.

Professor Veale has established an international reputation in translational research in the areas of angiogenesis, early arthritis, biopharmaceutical therapy, biomarkers and scleroderma. He has established an excellent research team including senior scientists, post-doctoral scientists, clinical research fellows and PhD students funded by peer-reviewed grants from The American Federation for Ageing Research, the European Union FP6 programme and Innovative Medicines Initiative (IMI), The Health Research Board of Ireland, Science Foundation Ireland, the Programme for Research in Third Level Institutions and a several of industry partnership programmes.

The Translational Research programme integrates immunology research across groups - colorectal, endocrine, hepatic and rheumatology in the ERC, the Conway Institute, UCD and TCD. Our primary clinical focus is on inflammatory arthritis and scientifically on hypoxia, angiogenesis and inflammation. In 2012, Professor Veale was elected to the Editorial Board of Annals of Rheumatic Disease (Impact Factor 9.111) and Rheumatology, and the EULAR Scientific Committee. He is a section chair and lead an abstract selection committee for the American College of Rheumatology.

 

Professional

Honours and Awards

Year: 2014.
Title: EULAR Rheumatology Centre of Excellence
Year: 2007.
Title: IJMS Best Rheumatology Paper 2007
Year: 2007.
Title: Beeson Award
Year: 2009.
Title: President, Scleroderma Clinical Trials Consortium

Associations

Association: Association of Physicians of Great Britain and Ireland, Function/Role: Member
Association: DAMC, Function/Role: Director of Translational Research
     

Conference Contributions

Prof D J Veale; (2011) International Visitors to St. Vincent's Unversity Hospital. [Conference Organising Committee Chairperson], Rheumatology Centre of Excellence, Dublin, St. Vincent's University Hospital , 23-JUN-11 - 24-JUN-11.
Prof D J Veale; (2011) Pathogenesis of Spondyloarthropathy. [Invited Lecture], German Kongress Rheumatology, Munich , 01-SEP-11 - 03-SEP-11.
Faculty; (2011) International Postgraduate Conference. [Conference Organising Committee Chairperson], RCPI Rheumatology Masterclass Series, RCPI , 20-OCT-11 - 21-OCT-11.

Committees

Committee : Irish Medicines Board
Committee : UCD Postgraduate committee

Employment

Employer: St. Vincent's University Hospital
Position: Consultant Rheumatologist
           

Publications

Books

Veale, D.J. and Fearon, U. (2007) Angiogenesis in psoriasis and psoriatic arthritis. : Elsevier Inc. [DOI] [Details]

Book Chapters

Firestein GS and Veale DJ (2015) 'Synovium' In: Kelley and Firestein (eds). Kelley and Firestein's Textbook of Rheumatology. Maryland Heights: Elsevier. [Details]
Carr H, Ryan J, Joyce M, Fitzgerald O, Veale D, Gibney R, Brennan ; (2008) 'A Topological Approach to Quantitation of Rheumatoid Arthritis' In: Carr H, Ryan J, Joyce M, Fitzgerald O, Veale D, Gibney R, Brennan ; (eds). Visualization in Medicine and Life Sciences. Berlin: Lecture Notes in Computer Science, Springer-Verlag. [Details]
 

Peer Reviewed Journals

Gudu T, Etcheto A;de Wit M;Heiberg T;Maccarone M;Balanescu A;Balint PV;Niedermayer DS;Ca¿¿ete JD;Helliwell P;Kalyoncu U;Kiltz U;Otsa K;Veale DJ;de Vlam K;Scrivo R;Stamm T;Kvien TK;Gossec L (2016) 'Fatigue in psoriatic arthritis¿¿-¿¿a cross-sectional study of 246¿¿patients from 13¿¿countries'. Joint Bone Spine, . [DOI] [Details]
Minnock P, Ringn¿¿r A;Bresnihan B;Veale D;FitzGerald O;McKee G (2016) 'Perceptions of the Cause, Impact and Management of Persistent Fatigue in Patients with Rheumatoid Arthritis Following Tumour Necrosing Factor Inhibition Therapy'. Musculoskeletal care, . [DOI] [Details]
O'Neill L, Rooney P;Molloy D;Connolly M;McCormick J;McCarthy G;Veale DJ;Murphy CC;Fearon U;Molloy E (2015) 'Regulation of Inflammation and Angiogenesis in Giant Cell Arteritis by Acute-Phase Serum Amyloid A'. Arthritis & rheumatology, 67 (9):2447-2456. [DOI] [Details]
Gossec L, Smolen JS;Ramiro S;de Wit M;Cutolo M;Dougados M;Emery P;Landew¿¿ R;Oliver S;Aletaha D;Betteridge N;Braun J;Burmester G;Ca¿¿ete JD;Damjanov N;FitzGerald O;Haglund E;Helliwell P;Kvien TK;Lories R;Luger T;Maccarone M;Marzo-Ortega H;McGonagle D;McInnes IB;Olivieri I;Pavelka K;Schett G;Sieper J;van den Bosch F;Veale DJ;Wollenhaupt J;Zink A;van der Heijde D (2015) 'European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update'. Annals of the Rheumatic Diseases, . [DOI] [Details]
T¿¿lli S, Etcheto A;Fautrel B;Balanescu A;Braun J;Ca¿¿ete JD;de Vlam K;de Wit M;Heiberg T;Helliwell P;Kalyoncu U;Kiltz U;Maccarone M;Niedermayer D;Otsa K;Scrivo R;Smolen JS;Stamm T;Veale DJ;Kvien TK;Gossec L (2015) 'Patient global assessment in psoriatic arthritis - what does it mean? An analysis of 223¿¿patients from the Psoriatic arthritis impact of disease (PsAID) study'. Joint Bone Spine, . [DOI] [Details]
Verheul MK, Fearon U;Trouw LA;Veale DJ (2015) 'Biomarkers for rheumatoid and psoriatic arthritis'. Clinical Immunology, 161 (1):2-10. [DOI] [Details]
Fearon U, Veale DJ (2015) 'Key Challenges in Rheumatic and Musculoskeletal Disease Translational Research'. EBioMedicine, 1 (2-3):95-96. [DOI] [Details]
Minnock P, Veale DJ;Bresnihan B;FitzGerald O;McKee G (2015) 'Factors that influence fatigue status in patients with severe rheumatoid arthritis (RA) and good disease outcome following 6¿¿months of TNF inhibitor therapy: a comparative analysis'. Journal of Clinical Rheumatology, 34 (11):1857-1865. [DOI] [Details]
Gao W, McGarry T;Orr C;McCormick J;Veale DJ;Fearon U (2015) 'Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and induction of negative feedback inhibitors'. Annals of the Rheumatic Diseases, . [DOI] [Details]
Connolly M, Rooney PR;McGarry T;Maratha AX;McCormick J;Miggin SM;Veale DJ;Fearon U (2015) 'Acute serum amyloid A is an endogenous TLR2 ligand that mediates inflammatory and angiogenic mechanisms'. Annals of the Rheumatic Diseases, . [DOI] [Details]
Basdeo SA, Moran B;Cluxton D;Canavan M;McCormick J;Connolly M;Orr C;Mills KH;Veale DJ;Fearon U;Fletcher JM (2015) 'Polyfunctional, Pathogenic CD161+ Th17 Lineage Cells Are Resistant to Regulatory T Cell-Mediated Suppression in the Context of Autoimmunity'. Journal of Immunology, 195 (2):528-540. [DOI] [Details]
Collins ES, Butt AQ;Gibson DS;Dunn MJ;Fearon U;van Kuijk AW;Gerlag DM;Pontifex E;Veale DJ;Tak PP;FitzGerald O;Pennington SR (2015) 'A clinically based protein discovery strategy to identify potential biomarkers of response to anti-TNF-¿¿ treatment of psoriatic arthritis'. Proteomics - Clinical Applications, . [DOI] [Details]
McGarry T, Veale DJ;Gao W;Orr C;Fearon U;Connolly M (2015) 'Toll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis'. Arthritis Research and Therapy, 17 . [DOI] [Details]
Humby F, Kelly S;Bugatti S;Manzo A;Filer A;Mahto A;Fonseca JE;Lauwerys B;D'Agostino MA;Naredo E;Lories R;Montecucco C;Tak PP;Fitzgerald O;Smith MD;Veale DJ;Choy EH;Strand V;Pitzalis C (2015) 'Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter-determining Validation Requirements'. Rheumatology, . [DOI] [Details]
Veale DJ, Fearon U (2015) 'What makes psoriatic and rheumatoid arthritis so different?'. RMD open, 1 (1). [DOI] [Details]
Muthana M, Hawtree S, Wilshaw A, Linehan E, Roberts H, Khetan S, Adeleke G, Wright F, Akil M, Fearon U, Veale D, Ciani B, Wilson AG (2015) 'C5orf30 is a negative regulator of tissue damage in rheumatoid arthritis'. PNAS, 112 (37):11618-11623. Available Online [Details]
Rooney, P. and Connolly, M. and Gao, W. and Mccormick, J. and Biniecka, M. and Sullivan, O. and Kirby, B. and Sweeney, C. and Molloy, E. and Markham, T. and Fearon, U. and Veale, D.J. (2014) 'Notch-1 mediates endothelial cell activation and invasion in psoriasis'. Experimental Dermatology, 23 (2):113-118. Available Online [DOI] [Details]
Minnock P, McKee G;Bresnihan B;FitzGerald O;Veale DJ (2014) 'How much is fatigue explained by standard clinical characteristics of disease activity in patients with inflammatory arthritis? A longitudinal study'. Arthritis Care and Research, 66 (11):1597-1603. [DOI] [Details]
Biniecka M, Connolly M;Gao W;Ng CT;Balogh E;Gogarty M;Santos L;Murphy E;Brayden D;Veale DJ;Fearon U (2014) 'Redox-mediated angiogenesis in the hypoxic joint of inflammatory arthritis'. Arthritis & rheumatology, 66 (12):3300-3310. [DOI] [Details]
Gossec, L. et al. (2014) 'A patient-derived and patient-reported outcome measure for assessing psoriatic arthritis: Elaboration and preliminary validation of the Psoriatic Arthritis Impact of Disease (PsAID) questionnaire, a 13-country EULAR initiative'. Annals of the Rheumatic Diseases, 73 (6):1012-1019. Available Online [DOI] [Details]
Strehl, C. and Fangradt, M. and Fearon, U. and Gaber, T. and Buttgereit, F. and Veale, D.J. (2014) 'Hypoxia: How does the monocyte-macrophage system respond to changes in oxygen availability?'. Journal of Leukocyte Biology, 95 (2):233-241. Available Online [DOI] [Details]
Orr, C. and Veale, D.J. (2014) 'Is there a need for new agents with novel mechanisms of action in psoriatic arthritis?'. Annals of the Rheumatic Diseases, 73 (6):951-953. Available Online [DOI] [Details]
Gao, W. and McCormick, J. and Connolly, M. and Balogh, E. and Veale, D.J. and Fearon, U. (2014) 'Hypoxia and STAT3 signalling interactions regulate pro-inflammatory pathways in rheumatoid arthritis'. Annals of the Rheumatic Diseases, . Available Online [DOI] [Details]
Maurer, B. et al. (2014) 'Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database'. Annals of the Rheumatic Diseases, . Available Online [DOI] [Details]
Balogh, E. and Dias, J.M. and Orr, C. and Mullan, R. and Harty, L. and FitzGerald, O. and Gallagher, P. and Molloy, M. and O'Flynn, E. and Kelly, A. and Minnock, P. and O'Neill, M. and Moore, L. and Murray, M. and Fearon, U. and Veale, D.J. (2013) 'Comparison of remission criteria in a tumour necrosis factor inhibitor treated rheumatoid arthritis longitudinal cohort: Patient global health is a confounder'. Arthritis Research and Therapy, 15 (6). Available Online [DOI] [Details]
Mullan, R.H. and Connolly, M. and Veale, D.J. and Fearon, U. (2013) 'Reply'. Arthritis and Rheumatism, 65 (1):284-285. Available Online [DOI] [Details]
O'Connell, C. and Hensey, M. and Mongey, A.B. and Veale, D.J. and Donnelly, S.C. (2013) 'A series of patients on anti-TNF therapy referred to a multidisciplinary lung cancer service'. Irish Journal of Medical Science, 182 (1):135-137. Available Online [DOI] [Details]
Szentpetery, A. and McKenna, M.J. and Murray, B.F. and Ng, C.T. and Brady, J.J. and Morrin, M. and Radovits, B. and Veale, D.J. and FitzGerald, O. (2013) 'Periarticular bone gain at proximal interphalangeal joints and changes in bone turnover markers in response to tumor necrosis factor inhibitors in rheumatoid and psoriatic arthritis'. Journal of Rheumatology, 40 (5):653-662. Available Online [DOI] [Details]
Gao, W. and Sweeney, C. and Walsh, C. and Rooney, P. and McCormick, J. and Veale, D.J. and Fearon, U. (2013) 'Notch signalling pathways mediate synovial angiogenesis in response to vascular endothelial growth factor and angiopoietin 2'. Annals of the Rheumatic Diseases, 72 (6):1080-1088. Available Online [DOI] [Details]
Cobb, J.E. and Plant, D. and Flynn, E. and Tadjeddine, M. and Dieudé, P. and Cornélis, F. and ÿrlestig, L. and Dahlqvist, S.R. and Goulielmos, G. and Boumpas, D.T. and Sidiropoulos, P. and Krintel, S.B. and ÿrnbjerg, L.M. and Hetland, M.L. and Klareskog, L. and Haeupl, T. and Filer, A. and Buckley, C.D. and Raza, K. and Witte, T. and Schmidt, R.E. and FitzGerald, O. and Veale, D. and Eyre, S. and Worthington, J. (2013) 'Identification of the Tyrosine-Protein Phosphatase Non-Receptor Type 2 as a Rheumatoid Arthritis Susceptibility Locus in Europeans'. PLoS ONE, 8 (6). Available Online [DOI] [Details]
Sullivan, C. and Sullivan, P. and Eadie, P. and Veale, D. (2013) 'Necrotizing fasciitis in patients on methotrexate therapy'. Journal of Clinical Rheumatology, 19 (5):289-291. Available Online [DOI] [Details]
Collins, E.S. and Galligan, M.C. and Saldova, R. and Adamczyk, B. and Abrahams, J.L. and Campbell, M.P. and Ng, C.-T. and Veale, D.J. and Murphy, T.B. and Rudd, P.M. and FitzGerald, O. (2013) 'Glycosylation status of serum in inflammatory arthritis in response to anti-TNF treatment'. Rheumatology (United Kingdom), 52 (9):1572-1582. Available Online [DOI] [Details]
O'Dwyer, D.N. and Armstrong, M.E. and Cooke, G. and Dodd, J.D. and Veale, D.J. and Donnelly, S.C. (2013) 'Rheumatoid Arthritis (RA) associated interstitial lung disease (ILD)'. European Journal of Internal Medicine, 24 (7):597-603. Available Online [DOI] [Details]
McMorrow, J.P. and Crean, D. and Gogarty, M. and Smyth, A. and Connolly, M. and Cummins, E. and Veale, D. and Fearon, U. and Tak, P.P. and Fitzgerald, O. and Murphy, E.P. (2013) 'Tumor necrosis factor inhibition modulates thrombospondin-1 expression in human inflammatory joint disease through altered nr4a2 activity'. American Journal of Pathology, 183 (4):1243-1257. Available Online [DOI] [Details]
Van Den Hoogen, F. and Khanna, D. and Fransen, J. and Johnson, S.R. and Baron, M. and Tyndall, A. and Matucci-Cerinic, M. and Naden, R.P. and Medsger Jr., T.A. and Carreira, P.E. and Riemekasten, G. and Clements, P.J. and Denton, C.P. and Distler, O. and Allanore, Y. and Furst, D.E. and Gabrielli, A. and Mayes, M.D. and Van Laar, J.M. and Seibold, J.R. and Czirjak, L. and Steen, V.D. and Inanc, M. and Kowal-Bielecka, O. and Müller-Ladner, U. and Valentini, G. and Veale, D.J. and Vonk, M.C. and Walker, U.A. and Chung, L. and Collier, D.H. and Csuka, M.E. and Fessler, B.J. and Guiducci, S. and Herrick, A. and Hsu, V.M. and Jimenez, S. and Kahaleh, B. and Merkel, P.A. and Sierakowski, S. and Silver, R.M. and Simms, R.W. and Varga, J. and Pope, J.E. (2013) '2013 classification criteria for systemic sclerosis: An american college of rheumatology/European league against rheumatism collaborative initiative'. Arthritis and Rheumatism, 65 (11):2737-2747. Available Online [DOI] [Details]
Van Den Hoogen, F. and Khanna, D. and Fransen, J. and Johnson, S.R. and Baron, M. and Tyndall, A. and Matucci-Cerinic, M. and Naden, R.P. and Medsger Jr., T.A. and Carreira, P.E. and Riemekasten, G. and Clements, P.J. and Denton, C.P. and Distler, O. and Allanore, Y. and Furst, D.E. and Gabrielli, A. and Mayes, M.D. and Van Laar, J.M. and Seibold, J.R. and Czirjak, L. and Steen, V.D. and Inanc, M. and Kowal-Bielecka, O. and Müller-Ladner, U. and Valentini, G. and Veale, D.J. and Vonk, M.C. and Walker, U.A. and Chung, L. and Collier, D.H. and Csuka, M.E. and Fessler, B.J. and Guiducci, S. and Herrick, A. and Hsu, V.M. and Jimenez, S. and Kahaleh, B. and Merkel, P.A. and Sierakowski, S. and Silver, R.M. and Simms, R.W. and Varga, J. and Pope, J.E. (2013) '2013 classification criteria for systemic sclerosis: An American college of rheumatology/European league against rheumatism collaborative initiative'. Annals of the Rheumatic Diseases, 72 (11):1747-1755. Available Online [DOI] [Details]
Veale, D.J. (2013) 'Psoriatic arthritis: Recent progress in pathophysiology and drug development'. Arthritis Research and Therapy, 15 (6). Available Online [DOI] [Details]
Marzaioli V, McMorrow JP, Angerer H, Gilmore A, Crean D, Zocco D, Rooney P, Veale D, Fearon U, Gogarty M, McEvoy AN, Stradner M and Murphy EP. (2012) 'Histamine contributes to increased RANKL/OPG ratio through altered NR4A activity in human chondrocyte cells'. Arthritis and Rheumatism, 64 (10):3290-3301. [Details]
Mix, KS,McMahon, K,McMorrow, JP,Walkenhorst, DE,Smyth, AM,Petrella, BL,Gogarty, M,Fearon, U,Veale, D,Attur, MG,Abramson, SB,Murphy, EP (2012) 'Orphan nuclear receptor NR4A2 induces synoviocyte proliferation, invasion, and matrix metalloproteinase 13 transcription'. Arthritis and Rheumatism, 64 :2126-2136. [DOI] [Details]
Gao, W,Sweeney, C,Connolly, M,Kennedy, A,Ng, CT,McCormick, J,Veale, DJ,Fearon, U (2012) 'Notch-1 mediates hypoxia-induced angiogenesis in rheumatoid arthritis'. Arthritis and Rheumatism, 64 :2104-2113. [DOI] [Details]
Fransen, J,Johnson, SR,van den Hoogen, F,Baron, M,Allanore, Y,Carreira, PE,Czirjak, L,Denton, CP,Distler, O,Furst, DE,Gabrielli, A,Herrick, A,Inanc, M,Kahaleh, B,Kowal-Bielecka, O,Medsger, TA,Mueller-Ladner, U,Riemekasten, G,Sierakowski, S,Valentini, G,Veale, D,Vonk, MC,Walker, U,Chung, L,Clements, PJ,Collier, DH,Csuka, ME,Jimenez, S,Merkel, PA,Seibold, JR,Silver, R,Steen, V,Tyndall, A,Matucci-Cerinic, M,Pope, JE,Khanna, D (2012) 'Items for developing revised classification criteria in systemic sclerosis: Results of a consensus exercise'. Arthritis Care and Research, 64 :351-357. [DOI] [Details]
Connolly M, Mullan RH, McCormick J, Matthews C, Sullivan O, Kennedy A, FitzGerald O, Poole AR, Bresnihan B, Veale DJ, Fearon U (2012) 'Acute-phase serum amyloid A regulates tumor necrosis factor α and matrix turnover and predicts disease progression in patients with inflammatory arthritis before and after biologic therapy'. Arthritis Rheumatology, . [Details]
Connolly M, Mullan RH, McCormick J, Matthews C, Sullivan O, Kennedy A, Fitzgerald O, Poole AR, Bresnihan B, Veale DJ, Fearon U (2011) 'A-SAA regulates TNFα and matrix turnover and predicts disease progression in patients pre/post biologic therapy'. Arthritis Rheumatology, . [Details]
Moran EM, Connolly M, Gao W, McCormick J, Fearon U, Veale DJ; (2011) 'Interleukin-17A induction of angiogenesis, cell migration, and cytoskeletal rearrangement'. Arthritis and Rheumatism, 63 (11):3263-3273. [DOI] [Details]
Biniecka M, Kennedy A, Ng CT, Chang TC, Balogh E, Fox E, Veale DJ, Fearon U, O'Sullivan JN; (2011) 'Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis'. Arthritis Research and Therapy, 13 (4). [DOI] [Details]
Saber T, Veale DJ, Balogh E, McCormick J, NicAnUltaigh S, Connolly M, Fearon U; (2011) 'Toll-like receptor 2 induced angiogenesis and invasion is mediated through the Tie2 signalling pathway in rheumatoid arthritis'. PLoS ONE, 6 (8). [DOI] [Details]
de Hair MJ, Harty LC, Gerlag DM, Pitzalis C, Veale DJ, Tak PP; (2011) 'Synovial tissue analysis for the discovery of diagnostic and prognostic biomarkers in patients with early arthritis'. Rheumatology, 38 (9):2068-2072. [DOI] [Details]
Moran EM, Heydrich R, Ng CT, Saber TP, McCormick J, Sieper J, Appel H, Fearon U, Veale DJ; (2011) 'IL-17A Expression Is Localised to Both Mononuclear and Polymorphonuclear Synovial Cell Infiltrates'. PLoS ONE, 6 (8). [DOI] [Details]
Adams R, Craig BM, Walsh CD, Veale DJ, Bresnihan B, FitzGerald O, Barry M; (2011) 'The impact of a revised EQ-5D population scoring on preference-based utility scores in an inflammatory arthritis cohort'. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 14 (6):921-927. [DOI] [Details]
van de Sande MG, Gerlag DM, Lodde BM, van Baarsen LG, Alivernini S, Codullo V, Felea I, Vieira-Sousa E, Fearon U, Reece R, Montecucco C, Veale DJ, Pitzalis C, Emery P, Klareskog L, McInnes IB, Tak PP; (2011) 'Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials'. Annals of the Rheumatic Diseases, 70 (3):423-427. [DOI] [Details]
Veale DJ; (2011) 'New therapies and new goals for psoriatic arthritis'. Arthritis and Rheumatism, 63 (4):874-876. [DOI] [Details]
Kennedy A, Ng CT, Chang TC, Biniecka M, O'Sullivan JN, Heffernan E, Fearon U, Veale DJ; (2011) 'Tumor necrosis factor blocking therapy alters joint inflammation and hypoxia'. Arthritis and Rheumatism, 63 (4):923-932. [DOI] [Details]
Nic An Ultaigh S, Saber TP, McCormick J, Connolly M, Dellacasagrande J, Keogh B, McCormack W, Reilly M, O'Neill LA, McGuirk P, Fearon U, Veale DJ; (2011) 'Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures'. Arthritis Research and Therapy, 13 (1). [DOI] [Details]
Huang A, Harty LC, Ryan CM, Veale DJ; (2011) 'Clinical images: infliximab therapy of polyarticular small joint sarcoid arthritis'. Arthritis and Rheumatism, 63 (7). [DOI] [Details]
Connolly M, Veale DJ, Fearon U; (2011) 'Acute serum amyloid A regulates cytoskeletal rearrangement, cell matrix interactions and promotes cell migration in rheumatoid arthritis'. Annals of the Rheumatic Diseases, 70 (7):1296-1303. [DOI] [Details]
Biniecka M, Fox E, Gao W, Ng CT, Veale DJ, Fearon U, O'Sullivan J; (2011) 'Hypoxia induces mitochondrial mutagenesis and dysfunction in inflammatory arthritis'. Arthritis and Rheumatism, 63 (8):2172-2182. [DOI] [Details]
Reid A, Brady A, Blake C, Mongey AB, Veale DJ, FitzGerald O, Cusack T; (2011) 'Randomised controlled trial examining the effect of exercise in people with rheumatoid arthritis taking anti-TNFα therapy medication'. BMC Musculoskeletal Disorders, . [Details]
Pontifex EK, Gerlag DM, Gogarty M, Vinkenoog M, Gibbs A, Burgman I, Fearon U, Bresnihan B, Tak PP, Gibney RG, Veale DJ, Fitzgerald O; (2011) 'Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with change in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy - a single centre, open-label study'. Arthritis Research & Therapy, . [Details]
Kennedy, A,Ng, CT,Chang, TC,Biniecka, M,O'Sullivan, JN,Heffernan, E,Fearon, U,Veale, DJ; (2011) 'Tumor Necrosis Factor Blocking Therapy Alters Joint Inflammation and Hypoxia'. Arthritis and Rheumatism, 63 :923-932. [DOI] [Details]
Connolly, M,Veale, DJ,Fearon, U; (2011) 'Acute serum amyloid A regulates cytoskeletal rearrangement, cell matrix interactions and promotes cell migration in rheumatoid arthritis'. Annals of the Rheumatic Diseases, 70 :1296-1303. [DOI] [Details]
Biniecka, M,Fox, E,Gao, W,Ng, CT,Veale, DJ,Fearon, U,O'Sullivan, J; (2011) 'Hypoxia Induces Mitochondrial Mutagenesis and Dysfunction in Inflammatory Arthritis'. Arthritis and Rheumatism, 63 :2172-2182. [DOI] [Details]
Saber, T,Veale, DJ,Balogh, E,McCormick, J,NicAnUltaigh, S,Connolly, M,Fearon, U; (2011) 'Toll-Like Receptor 2 Induced Angiogenesis and Invasion Is Mediated through the Tie2 Signalling Pathway in Rheumatoid Arthritis'. PLoS ONE, 6 . [DOI] [Details]
Veale, DJ; (2011) 'New Therapies and New Goals for Psoriatic Arthritis'. Arthritis and Rheumatism, 63 :874-876. [DOI] [Details]
Reid A, Brady A, Blake C, Mongey AB, Veale DJ, Filzgerald O, Cusack T.; (2011) 'Randomised controlled trial examining the effect of exercise in people with Rheumatoid Arthritis taking TNFalpha therapy medication'. BMC Musculoskeletal Disorders, 12 (11). Available Online [DOI] [Details]
Pontifex EK, Gerlag DM, Gogarty M, Vinkenoog M, Gibbs A, Burgman I, Fearon U, Bresnihan B, Tak PP, Gibney RG, Veale DJ, Fitzgerald O; (2011) 'Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with change in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy - a single centre, open-label study'. Arthritis Research and Therapy, 13 (1). [DOI] [Details]
Walsh CE, Ryan EJ, O'Farrelly C, Golden-Mason L, FitzGerald O, Veale DJ, Bresnihan B, Fearon U (2011) 'Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease'. PLoS ONE, . [Details]
Saber, TP,Ng, CT,Renard, G,Lynch, BM,Pontifex, E,Walsh, CAE,Grier, A,Molloy, M,Bresnihan, B,FitzGerald, O,Fearon, U,Veale, DJ; (2010) 'Remission in psoriatic arthritis: is it possible and how can it be predicted?'. Arthritis Research and Therapy, 12 . [DOI] [Details]
Englbrecht M, Wang Y, Ronneberger M, Manger B, Vastesaeger N, Veale DJ, Schett G; (2010) 'Measuring joint involvement in polyarticular psoriatic arthritis: an introduction of alternatives'. Arthritis Care and Research, 62 (7):977-983. [DOI] [Details]
Mullan RH, McCormick J, Connolly M, Bresnihan B, Veale DJ, Fearon U; (2010) 'A role for the high-density lipoprotein receptor SR-B1 in synovial inflammation via serum amyloid-A'. Pathology, 176 (4):1999-2008. [DOI] [Details]
Harty LC, Veale DJ; (2010) 'Irish smokers with rheumatoid arthritis suffer more than their nonsmoking counterparts'. Rheumatology, 37 (5). [DOI] [Details]
Tobin AM, Veale DJ, Fitzgerald O, Rogers S, Collins P, O'Shea D, Kirby B; (2010) 'Cardiovascular disease and risk factors in patients with psoriasis and psoriatic arthritis'. Rheumatology, 37 (7):1386-1394. [DOI] [Details]
Harty L, Veale DJ; (2010) 'How early should psoriatic arthritis be treated with a TNF-blocker?'. Current Opinion in Rheumatology, 22 (4):393-396. [DOI] [Details]
Veale DJ; (2010) 'What can we learn from negative clinical trials in systemic sclerosis?'. Clinical and Experimental Rheumatology, 28 (2 Suppl 58):1-4. [Details]
Rooney T, Roux-Lombard P, Veale DJ, FitzGerald O, Dayer JM, Bresnihan B; (2010) 'Synovial tissue and serum biomarkers of disease activity, therapeutic response and radiographic progression: analysis of a proof-of-concept randomised clinical trial of cytokine blockade'. Annals of the Rheumatic Diseases, 69 (4):706-714. [DOI] [Details]
Biniecka M, Kennedy A, Fearon U, Ng CT, Veale DJ, O'Sullivan JN; (2010) 'Oxidative damage in synovial tissue is associated with in vivo hypoxic status in the arthritic joint'. Annals of the Rheumatic Diseases, 69 (6):1172-1178. [DOI] [Details]
Rooney T, Edwards CK 3rd, Gogarty M, Greenan L, Veale DJ, FitzGerald O, Dayer JM, Bresnihan B; (2010) 'Synovial tissue rank ligand expression and radiographic progression in rheumatoid arthritis: observations from a proof-of-concept randomized clinical trial of cytokine blockade'. Rheumatology International, 30 (12):1571-1580. [DOI] [Details]
Kennedy A, Ng CT, Biniecka M, Saber T, Taylor C, O'Sullivan J, Veale DJ, Fearon U; (2010) 'Angiogenesis and blood vessel stability in inflammatory arthritis'. Arthritis and Rheumatism, 62 (3):711-721. [DOI] [Details]
Connolly, M,Marrelli, A,Blades, M,McCormick, J,Maderna, P,Godson, C,Mullan, R,FitzGerald, O,Bresnihan, B,Pitzalis, C,Veale, DJ,Fearon, U; (2010) 'Acute Serum Amyloid A Induces Migration, Angiogenesis, and Inflammation in Synovial Cells In Vitro and in a Human Rheumatoid Arthritis/SCID Mouse Chimera Model'. J IMMUNOL, 184 :6427-6437. [DOI] [Details]
Martin, J,Walsh, C,Gibbs, A,McDonnell, T,Fearon, U,Keane, J,Codd, MB,Dodd, J,Veale, D,FitzGerald, O,Bresnihan, B; (2010) 'Comparison of interferon gamma release assays and conventional screening tests before tumour necrosis factor alpha blockade in patients with inflammatory arthritis'. Annals of the Rheumatic Diseases, 69 :181-185. [DOI] [Details]
Kennedy A, Ng CT, Biniecka M, Saber J, Taylor C, O¿Sullivan J, Veale DJ, Fearon U.; (2010) 'Angiogenesis and Blood Vessel Stability in Inflammatory Synovial Tissue'. Arthritis and Rheumatism, 62 (3):711-721. [Details]
Ng CT, Radovits BJ, Kievit W, Fransen J, van Riel PL, FitzGerald O, Veale DJ, Bresnihan B.; (2010) 'Unregulated prescribing of anti-tumour necrosis factor agents does not mean inappropriate prescribing'. Annals of Rheumatic Diseases, . [Details]
Adams R, Walsh C, Veale D, Bresnihan B, FitzGerald O, Barry M; (2010) 'Understanding the relationship between the EQ-5D, SF-6D, HAQ and disease activity in inflammatory arthritis'. . [Details]
Ng, CT,Biniecka, M,Kennedy, A,McCormick, J,FitzGerald, O,Bresnihan, B,Buggy, D,Taylor, CT,O'Sullivan, J,Fearon, U,Veale, DJ; (2010) 'Synovial tissue hypoxia and inflammation in vivo'. Annals of the Rheumatic Diseases, 69 :1389-1395. [DOI] [Details]
Minnock, P,Kirwan, J,Veale, D,FitzGerald, O,Bresnihan, B; (2010) 'Fatigue is an independent outcome measure and is sensitive to change in patients with psoriatic arthritis'. Clinical and Experimental Rheumatology, 28 :401-404. [Details]
Pearman L, Last J, Fitzgerald O, Veale D, Joyce M, Rainford L, McEntee M, McNulty J, Thomas E, Ryan J, McGee A, Toomey R, D'Helft C, Lowe J, Brennan PC (2009) 'Rheumatoid arthritis: a novel radiographic projection for hand assessment'. British Journal of Radiology, 82 (979):554-560. [Details]
Oliver KM, Garvey JF, Ng CT, Veale DJ, Fearon U, Cummins EP, Taylor CT; (2009) 'Hypoxia activates NF-kappaB-dependent gene expression through the canonical signaling pathway'. Antioxidants and Redox Signaling, 11 (9):2057-2064. [DOI] [Details]
Moran EM, Mullan R, McCormick J, Connolly M, Sullivan O, Fitzgerald O, Bresnihan B, Veale DJ, Fearon U; (2009) 'Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-alpha, Oncostatin M and response to biologic therapies'. Arthritis Research and Therapy, 11 (4). [DOI] [Details]
Saber TP, Veale DJ; (2009) 'Psoriatic arthritis management update - biotherapeutic options'. Rheumatology, 83 :65-68. [DOI] [Details]
Doran JP, Alraqi S, Callanan I, Fitzgerald O, Bresnihan B, Veale DJ; (2009) 'An audit of hospital based outpatient infusions and a pilot program of community-based monoclonal antibody infusions'. IRISH JOURNAL OF MEDICAL SCIENCE, . [Details]
Martin J, Walsh C, Gibbs A, McDonnell T, Fearon U, Keane J, Codd MB, Dodd JD, Veale D, Fitzgerald O, Bresnihan B; (2009) 'Comparison of interferon-{gamma}-release assays and conventional screening tests before tumour necrosis factor-{alpha} blockade in patients with inflammatory arthritis'. Annals of Rheumatic Diseases, . [Details]
Rooney T, Roux-Lombard P, Veale DJ, Fitzgerald O, Dayer JM, Bresnihan B; (2009) 'Synovial tissue and serum biomarkers of disease activity, therapeutic response and radiographic progression. analysis of a proof-of-concept randomized clinical trial of cytokine blockade'. Annals of Rheumatic Diseases, . [Details]
Bresnihan B, Pontifex E, Thurlings RM, Vinkenoog M, El-Babalawy H, Fearon U, Fitzgerald O, Gerlag DM, Rooney T, van de Sande MG, Veale D, Vos K, Tak PP; (2009) 'Synovial tissue sublining CD68 expression is a biomarker of therapeutic response in rheumatoid arthritis clinical trials: consistency across centers'. Journal of Rheumatology, . [Details]
Rooney T, Edwards CK 3rd, Gogarty M, Greenan L, Veale DJ, Fitzgerald O, Dayer JM, Bresnihan B; (2009) 'Synovial tissue rank ligand expression and radiographic progression in rheumatoid arthritis: observations from a proof-of-concept randomized clinical trial of cytokine blockade'. Rheumatology International, . [Details]
Burgoyne CH, Field SL, Brown AK, Hensor EM, English A, Bingham SL, Verburg R, Fearon U, Lawson CA, Hamlin PJ, Straszynski L, Veale D, Conaghan P, Hull MA, van Laar JM, Tennant A, Emery P, Isaacs JD, Ponchel F; (2008) 'Abnormal T cell differentiation persists in patients with rheumatoid arthritis in clinical remission and predicts relapse'. Annals of the Rheumatic Diseases, 67 (6):750-757. [DOI] [Details]
Veale DJ, Woolf AD, Carr AJ; (2008) 'Chronic musculoskeletal pain and arthritis: impact, attitudes and perceptions'. Irish Medical Journal, 101 (7):208-210. [Details]
Ng CT, O'Neil M, Walsh D, Walsh T, Veale DJ; (2008) 'Successful pregnancy after rituximab in a women with recurrent in vitro fertilisation failures and anti-phospholipid antibody positive'. Medicine, . [DOI] [Details]
O'Kane, M,Markham, T,McEvoy, AN,Fearon, U,Veale, DJ,FitzGerald, O,Kirby, B,Murphy, EP; (2008) 'Increased expression of the orphan nuclear receptor NURR1 in psoriasis and modulation following TNF-alpha inhibition'. Journal of Investigative Dermatology, 128 :300-310. [DOI] [Details]
Walsh CA, Fearon U, Fitzgerald O, Veale DJ, Bresnihan B.; (2008) 'Decreased CD20 expression in rheumatoid arthritis synovium following eight weeks of rituximab therapy'. Clinical and Experimental Rheumatology, . [Details]
Pearman L, FitzGerald O, Veale D, Joyce M, Rainford L, McNulty J, Thomas E, Ryan J, Toomey, R, Lowe J, Brennan PC. ; (2008) 'Rheumatoid Arthritis: the UCD projection for hand and wrist assessment, a novel technique'. British Journal of Radiology, . [Details]
Fearon U, Veale DJ; (2007) 'Angiogenesis in arthritis: methodological and analytical details'. Methods, 135 :343-357. [Details]
Brulhart, L., Ng, C. T., Codd, M. B., Walsh, C. A. E., Pontifex, E. K., Lynch, B., Grier, A., Molloy, M., O'Flynn, E., Bresnihan, B., FitzGerald, O., Veale, D. J., ; (2007) 'Co-medication with methotrexate is not associated with remission in psoriatic arthritis patients on TNFI inhibitors treatment'. Arthritis and Rheumatism, 56 (12):4298-4299. [Details]
Bresnihan B, Gerlag DM, Rooney T, Smeets TJ, Wijbrandts CA, Boyle D, Fitzgerald O, Kirkham BW, McInnes IB, Smith M, Ulfgren AK, Veale DJ, Tak PP.; (2007) 'Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: standardization and consistency across centers'. Journal of Rheumatology, 34 (3):620-622. [Details]
Gladman DD, Mease PJ, Healy P, Helliwell PS, Fitzgerald O, Cauli A, Lubrano E, Krueger GG, van der Heijde D, Veale DJ, Kavanaugh A, Nash P, Ritchlin C, Taylor W, Strand V.; (2007) 'Outcome measures in psoriatic arthritis'. Journal of Rheumatology, 34 (5):1159-1166. [Details]
Walsh CA, Minnock P, Slattery C, Kennedy N, Pang F, Veale DJ, Bresnihan B, Fitzgerald O.; (2007) 'Quality of life and economic impact of switching from established infliximab therapy to adalimumab in patients with rheumatoid arthritis'. Journal of Rheumatology, 46 (7):1148-1152. [Details]
Mullan RH, Matthews C, Bresnihan B, Fitzgerald O, King L, Poole AR, Fearon U, Veale DJ.; (2007) 'Early changes in serum type II collagen biomakers predict radiographic progression at one year in inflammatory arthritis patients after biological therapy'. Arthritis and Rheumatism, . [Details]
O'Kane M, Markham T, Mc Evoy TN, Fearon U, Veale DJ, Fitzgerald O, Kirby B, Murphy EP. ; (2007) 'Increased expression of the orphan nuclear receptor NURR1 in psoriasis and modulation following TNF-alpha inhibition'. Journal of Investigative Dermatology, . [Details]
Greetham D, Ellis CD, Mewar D, Fearon U, an Ultaigh SN, Veale DJ, Guesdon F, Wilson AG; (2007) 'Functional characterization of NF-kappaB inhibitor-like protein 1 (NFkappaBIL1), a candidate susceptibility gene for rheumatoid arthritis'. Human Molecular Genetics, 16 (24):3027-3036. [DOI] [Details]
Smith MD, Baeten D, Ulfgren AK, McInnes IB, Fitzgerald O, Bresnihan B, Tak PP, Veale D; OMERACT synovial special interests group.; (2006) 'Standardisation of synovial tissue infiltrate analysis: how far have we come? How much further do we need to go?'. Annals of Rheumatic Diseases, 65 (1):93-100. Available Online [Details]
Smith MD, Baeten D, Ulfgren AK, McInnes IB, Fitzgerald O, Bresnihan B, Tak PP, Veale D; (2006) 'OMERACT synovial special interests group. Standardisation of synovial tissue infiltrate analysis: how far have we come? How much further do we need to go?'. Annals of Rheumatic Diseases, 65 (1):93-100. [Details]
Mullan, RH; Fearon, U; Mathews, C; Lobanok, T; King, L; FitzGerald, O; Bresnihan, B; Poole, R; Veale, DJ; ; (2006) 'Serum amyloids a (A-SAA) correlates with joint damage in vivo and induces cartilage matrix degradation in vitro'. Arthritis and Rheumatism, 54 (9):595-596. [Details]
Markham T, Mathews C, Rogers S, Mullan R, Bresnihan B, Fitzgerald O, Veale DJ, Fearon U.; (2006) 'Downregulation of the inhibitor of apoptosis protein survivin in keratinocytes and endothelial cells in psoriasis skin following infliximab therapy'. British Journal of Dermatology, 155 (6):1191-1196. [Details]
Markham T, Mullan R, Golden-Mason L, Rogers S, Bresnihan B, Fitzgerald O, Fearon U, Veale DJ.; (2006) 'Resolution of endothelial activation and down-regulation of Tie2 receptor in psoriatic skin after infliximab therapy'. Journal of the American Academy of Dermatology, 54 (6):1003-1012. [Details]
Mullan RH, Bresnihan B, Golden-Mason L, Markham T, O'Hara R, FitzGerald O, Veale DJ, Fearon U.; (2006) 'Acute-phase serum amyloid A stimulation of angiogenesis, leukocyte recruitment, and matrix degradation in rheumatoid arthritis through an NF-kappaB-dependent signal transduction pathway'. Arthritis and Rheumatism, 54 (1):105-114. [Details]
Pontifex, E; Gogarty, M; Murphy, E; Bresnihan, B; Veale, D; FitzGerald, O; ; (2006) 'JunB expression in psoriatic arthritis synovium and skin pre- and post-treatment with etanercept'. Arthritis and Rheumatism, 54 (9):466-466. [Details]
Veale, DJ; Fearon, U; ; (2006) 'Inhibition of angiogenic pathways in rheumatoid arthritis: potential for therapeutic targeting'. Best Practice and Research in Clinical Rheumatology, 20 (5):941-947. [Details]
Fearon, U; Mullan, R; Markham, T; Connolly, M; Sullivan, S; Poole, AR; FitzGerald, O; Bresnihan, B; Veale, DJ; ; (2006) 'Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures'. Arthritis and Rheumatism, 54 (10):3152-3162. [Details]
Benito, M.J., Veale, D.J., FitzGerald, O., van de Berg, W.B., Bresnihan ,B.; (2005) 'Synovial tissue inflammation in early and late osteoarthritis'. ANNALS OF RHEUMATIC DISEASES, . [Details]
Smith, M.D., Baeten, D., Ulfgren, A.K., McInnes, I.B., Fitzgerald, O., Bresnihan, B., Tak, P.P., Veale D.J.; (2005) 'Standardisation of synovial tissue infiltrate analysis: how far have we come? How much further do we need to go?'. ANNALS OF RHEUMATIC DISEASES, . [Details]
Leong TT, Fearon U, Veale DJ.; (2005) 'Angiogenesis in psoriasis and psoriatic arthritis: clues to disease pathogenesis'. Current Rheumatology Report, 7 (4):325-329. [Details]
Veale DJ, Ritchlin C, FitzGerald O.; (2005) 'Immunopathology of psoriasis and psoriatic arthritis'. Annals of the Rheumatic Diseases, 64 Suppl. 2 (ii):26-29. Available Online [Details]
Bresnihan, B; Baeten, D; Firestein, GS; Fitzgerald, OM; Gerlag, DM; Haringman, JJ; McInnes, IB; Reece, RJ; Smith, MD; Ulfgren, AK; Veale, DJ; Tak, PP; ; (2005) 'Synovial tissue analysis in clinical trials'. Rheumatology, 32 (12):2481-2484. [Details]
Mullan, RH; Lobanok, T; Walsh, C; King, L; FitzGerald, O; Bresnihan, B; Fearon, U; Poole, R; Veale, DJ; ; (2005) 'The value of serum type II collagen epitope measurement in assessing early clinical response to treatment with anti-tumour necrosis factor alpha therapy in rheumatoid arthritis'. Arthritis Research and Therapy, 7 (NA):24-25. [Details]
Gogarty, M; Murphy, E; Veale, D; Bresnihan, B; Fitzgerald, O; ; (2005) 'Alternative splicing of the VEGFR-1 (flt-1) and its ligands in human inflammatory arthritis'. Arthritis and Rheumatism, 52 (9):52-52. [Details]
Mullan, RH; Golden-Mason, L; Markham, T; O'Hara, R; FitzGerald, O; Bresnihan, B; Veale, DJ; Fearon, U; ; (2004) 'Acute-phase serum amyloid a stimulates angiogenesis, leukocyte recruitment and matrix degradation in RA via NF kappa B and MAPK-dependent pathways'. Arthritis and Rheumatism, 50 (12):4102-4102. [Details]
Woolf AD, Zeidler H, Haglund U, Carr AJ, Chaussade S, Cucinotta D, Veale DJ, Martin-Mola E. ; (2004) 'Musculoskeletal pain in Europe: its impact and a comparison of population and medical perceptions of treatment in eight European countries'. Annals of Rheumatic Diseases, 63 (4):342-347. [Details]
Karim Z, Wakefield RJ, Quinn M, Conaghan PG, Brown AK, Veale DJ, Connor PO, Reece R, Emery P. ; (2004) 'Validation and reproducibility of ultrasonography in the detection of synovitis in the knee: A comparison with arthroscopy and clinical examination'. Arthritis and Rheumatism, 50 (2):387-394. [Details]
O'Kane, M; Kirby, B; Fitzgerald, O; Veale, D; Markham, T; Murphy, E; ; (2004) 'Corticotropin-releasing hormone - a possible role in psoriasis'. British Journal of Dermatology, 151 (NA):49-49. [Details]
Mullan, RH; Lobanok, T; Walsh, E; King, L; FitzGerald, O; Bresnihan, B; Fearon, U; Poole, R; Veale, DJ; ; (2004) 'The value of serum type II collagen epitope measurement in assessing early clinical response to treatment with anti-TNF-alpha therapy in rheumatoid arthritis'. Arthritis and Rheumatism, 50 (12):4094-4094. [Details]
Duffy, TN; Fearon, U; Godson, C; Brady, H; Bresnihan, B; Veale, D; FitzGerald, O; ; (2003) 'Profibrotic mRNA is preferentially expressed in bone forming arthritis'. Arthritis and Rheumatism, 48 (9):602-602. [Details]
Fearon U, Griosios K, Fraser A, Reece R, Emery P, Jones PF, Veale DJ. ; (2003) 'Angiopoietins, growth factors, and vascular morphology in early arthritis'. Journal of Rheumatology, 30 (2):260-268. [Details]
Mullan, RH; Mason, LG; Markham, T; O'Hara, R; FitzGerald, O; Bresnihan, B; Veale, DJ; Fearon, U; ; (2003) 'A novel role for serum Amyloid-A (A-SAA) in angiogenesis and adhesion molecule expression through an NF kappa B-dependent signal transduction pathway'. Arthritis and Rheumatism, 48 (12):3624-3624. [Details]
Fraser, A,Fearon, U,Billinghurst, RC,Ionescu, M,Reece, R,Barwick, T,Emery, P,Poole, AR,Veale, DJ; (2003) 'Turnover of type II collagen and aggrecan in cartilage matrix at the onset of inflammatory arthritis in humans - Relationship to mediators of systemic and local inflammation'. Arthritis and Rheumatism, 48 :3085-3095. [DOI] [Details]
Veale, D; FitzGerald, O; ; (2002) 'Psoriatic arthritis'. Best Practice and Research in Clinical Rheumatology, 16 (4):523-535. [Details]
Bingham S, Veale D, Fearon U, Isaacs JD, Morgan G, Emery P, McGonagle D, Reece R, Clague R, Snowden JA. ; (2002) 'High-dose cyclophosphamide with stem cell rescue for severe rheumatoid arthritis: short-term efficacy correlates with reduction of macroscopic and histologic synovitis'. Arthritis and Rheumatism, 46 (3):837-839. [Details]
Fraser A, Fearon U, Reece R, Emery P, Veale DJ; (2001) 'Matrix metalloproteinase 9, apoptosis, and vascular morphology in early arthritis'. Arthritis and Rheumatism, 44 (9):2024-2028. [Details]
Ali M, Ponchel F, Wilson KE, Francis MJ, Wu X, Verhoef A, Boylston AW, Veale DJ, Emery P, Markham AF, Lamb JR, Isaacs JD. ; (2001) 'Rheumatoid arthritis synovial T cells regulate transcription of several genes associated with antigen-induced anergy'. Journal of Clinical Investigation, 107 (4):519-528. [Details]
Fearon U, Reece R, Smith J, Emery P, Veale DJ. ; (1999) 'Synovial cytokine and growth factor regulation of MMPs/TIMPs: implications for erosions and angiogenesis in early rheumatoid and psoriatic arthritis patients'. Annals of the New York Academy of Science, 878 :619-621. [Details]
Reece RJ, Canete JD, Parsons WJ, Emery P, Veale DJ. ; (1999) 'Distinct vascular patterns of early synovitis in psoriatic, reactive, and rheumatoid arthritis'. Arthritis and Rheumatism, 42 (7):1481-1484. [Details]
Veale DJ, Reece RJ, Parsons W, Radjenovic A, O'Connor PJ, Orgles CS, Berry E, Ridgway JP, Mason U, Boylston AW, Gibbon W, Emery P. ; (1999) 'Intra-articular primatised anti-CD4: efficacy in resistant rheumatoid knees. A study of combined arthroscopy, magnetic resonance imaging, and histology'. Annals of Rheumatic Diseases, 58 (6):342-349. [Details]
Youssef, PP; Kraan, M; Breedveld, F; Bresnihan, B; Cassidy, N; Cunnane, G; Emery, P; Fitzgerald, O; Kane, D; Lindblad, S; Reece, R; Veale, D; Tak, PP; ; (1998) 'Quantitative microscopic analysis of inflammation in rheumatoid arthritis synovial membrane samples selected at arthroscopy compared with samples obtained blindly by needle biopsy'. Arthritis and Rheumatism, 41 (4):663-669. [Details]
Youssef, PP; Breedveld, FC; Bresnihan, B; Cassidy, N; Cunnane, G; Emery, P; FitzGerald, O; Kane, D; Kraan, M; Lindblad, S; Reece, R; Veale, D; Tak, PP; ; (1997) 'Quantitative microscopic analysis of inflammation in rheumatoid arthritis synovial membrane samples selected at arthroscopy compared with samples taken blindly by needle biopsy'. Arthritis and Rheumatism, 40 (9):1555-1555. [Details]
Mulherin, DM; Veale, DJ; Belch, JJF; Bresnihan, B; Fitzgerald, O; ; (1996) 'Adhesion molecule in untreated inflammatory arthritis'. Qjm-An International Journal Of Medicine, 89 (3):195-203. [Details]

Other Journals

Smith, M.D., Baeten, D., Ulfgren, A.K., McInnes, FitzGerald, O., Bresnihan, B., Tak, P.P. Veale, D.; (2006) 'Standardisation of synovial tissue infiltrate analysis: how far have we come? How much farther do we need to go? OMERACT 7 synovial special interest group: Review' Annals of the Rheumatic Diseases . [Details]
Markham, T., Mullan, R., Golden-Mason, L., Rogers, S., Bresnihan, B., FitzGerald, O., Fearon, U. Veale, D.J.; (2005) 'Resolution of endothelial activation and down-regulation of Tie2 receptor in psoriatic skin after infliximab therapy' J Am Acad Dermatol . [Details]
Bresnihan, B., Baeten, D., Firestein, G.S., FitzGerald, O.M., Gerlag, D.M., Haringman, J.J., McInnes, I.B., Reece, R.J., Smith, M.D., Ulfgren, A.K., Veale, D.J. Tak, P.P.; (2005) 'Synovial tissue analysis in clinical trials: OMERACT 7 Special Interest Group: Review' Journal of Rheumatology . [Details]

Conference Publications

Gogarty, M., Murphy, E.P., Veale, D., Bresnihan, B., FitzGerald, O.; Alternative splicing of the VEGFR-1 (flt-1) and its ligands in human inflammatory arthritis ARTHRITIS AND RHEUMATISM [Details]
Reid A., Brady A., Mongey A., Veale D.J., FitzGerald O., Blake C., Cusack T.; (2011) EFFECT OF DYNAMIC EXERCISE ON FUNCTION IN PEOPLE WITH RHEUMATOID ARTHRITIS TAKING ANTI-TNF MEDICATION: RESULTS OF A RCT World Confederation for Physical Therapy Amsterdam, , 20-JUN-11 - 23-JUN-11 [Details]
Moran, EM, Ng, CT, McCormack, J, Heydrich, R, Appel, H, Fearon, U, Veale, DJ (2010) IL-17A expression is upregulated in the hypoxic joint and correlates with IL-6 production, inflammatory cell infiltrate and oxidative damage Irish Society for Rheumatology & Irish Rheumatology Health Professionals Society - Autumn Scientific Meeting 2009 [DOI] [Details]
Ryan J, NG CT, Gibney R, Fitzgerald O, Brennan P, Hefferenan E, Fearon U, McNulty J, Rainford L, Veale D; (2010) Novel PET/MR Fusion Imaging and Quantification of Knee Synovitis in Rheumatoid Arthritis American College of Rheumatology Annual Scientific Meeting Atlanta, USA, Available Online [Details]
Reid A, Brady A, Cusack T, Blake C, Monget AB, Veale D, FitzGerald O.; (2010) Improvements in Function Following Dynamic Exercise in Patients with RA taking anti-TNFα Therapy Reflected in Lower Limb Function Tests but not the HAQ American College of Rheumatologists Atlanta, USA, , 08-NOV-10 - 13-NOV-10 [Details]
Bresnihan, B,Pontifex, E,Thurlings, RM,Vinkenoog, M,El-Gabalawy, H,Fearon, U,Fitzgerald, O,Gerlag, DM,Rooney, T,van de Sande, MG,Veale, D,Vos, K,Tak, PP (2009) JOURNAL OF RHEUMATOLOGY Synovial Tissue Sublining CD68 Expression Is a Biomarker of Therapeutic Response in Rheumatoid Arthritis Clinical Trials: Consistency Across Centers , pp.1800-1802 [DOI] [Details]
O'Kane, M., Markham, T., McEvoy, A. N., Fearon, U., Veale, D. J., FitzGerald, O., Kirby, B., Murphy, E. P., ; (2008) Journal of Investigative Dermatology Increased expression of the orphan nuclear receptor NURR1 in psoriasis and modulation following TNF-alpha inhibition , pp.300-310 [Details]
Bresnihan, B,Gerlag, DM,Rooney, T,Smeets, TJM,Wijbrandts, CA,Boyle, D,Fitzgerald, O,Kirkham, BW,McInnes, IB,Smith, M,Ulfgren, AK,Veale, DJ,Tak, PP (2007) JOURNAL OF RHEUMATOLOGY Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: Standardization and consistency across centers , pp.620-622 [Details]
Gogarty, M., Murphy, E. P., Fearon, U., Veale, D. J., Bresnihan, B., FitzGerald, O., ; (2007) Annals of the Rheumatic Diseases Abundant placenta growth factor (PlGF) expression in the inflammatory joint , pp.141-141 [Details]
Gogarty, M, Murphy, EP, Fearon, U, Veale, DJ, Bresnihan, B, FitzGerald, O, ; (2007) ANN RHEUM DIS Placenta growth factor (PLGF) expression in inflammatory arthritis , pp.35-36 [Details]
Garraud C, Ryan J, Carr H, Gibney R, Veale D, Fitzgerald O, Brennan PC; (2007) A volumetric reconstruction method for semi-automatic quantification of rheumatoid arthritis within the knee Virtual Reality Interactions and Physical Simulations [Details]
Gibbs, A., FitzGerald, O., Bresnihan, B. Veale, D.; (2005) A review of the use of magnetic resonance imaging (MRI) to diagnose spondylarthropathy early American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Gogarty, M., Murphy, E., Veale, D.J., Bresnihan, B. FitzGerald, O.; (2005) Alternative splicing of the VEGFR-1 (flt-1) and its ligands in human inflammatory arthritis American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Mullan, R., Mathews, C., Lobanok, T., Kind, L., Walsh, C., FitzGerald, O., Bresnihan, B., Fearon, U., Poole, R. Veale, D.; (2005) Serum type II collagen epitope measurement predicts radiographic progression during treatment with anti-TNF alpha therapy American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Rooeny, T., Roux-Lombard, P., Veale, D.J., FitzGerald, O., Dayer, J.-M. Bresnihan, B.; (2005) Serum biomarkers of disease activity and radiographic progression in patients receiving biologic therapies for rheumatoid arthritis American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Martin, J., FitzGerald, O., Veale, D., McDonnell, T. Bresnihan, B.; (2005) Screening for latent tuberculosis infection prior to anti-TNF alpha treatment American Colelge of Rheumatology AGM [Details]
O'Rourke, M., FitzGerald, O., Bresnihan, B., Rogers-Gray, B., Winstone, J.M., Buchan, S. Veale, D.; (2005) Infliximab use in psoriatic arthritis : Clinical effectivemess and impact on quality of life American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Walsh, C., O'Farrelly, C., Golden-Mason, L., Veale, D., FitzGerald, O., Bresnihan, B. Veale, D.; (2005) Expansion of T cells expressing CD94/NKG2A in patients with rheumatoid arthritis in clinical remission following treatment with anti-TNF alpha agents American Colelge of Rheumatology AGM [Details]
Gibbs, A., Markham, T., Walsh, C., Bresnihan, B., Veale, D. FitzGerald.; (2005) Anakinra (Kineret) in psoriasis and psoriatic arthritis: a single centre, open label pilot study American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Connolly, M., Mullan, R., Sweeney, C., FitzGerald, O., Bresnihan, B., Veale, D.J. Fearon, U.; (2005) A-SAA induces chemokine expression, cell invasion and cytoskeletal disassembly in RA synovial tissue in part through P13 kinase pathway American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Greenan, L., Rooney, T., FitzGerald, Veale, D., Fearon, U. Bresnihan, B.; (2005) Characterisation of RA synovial membrane and synovial fibroblasts before and following anti-cytokine therapy American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Gogarty, M., Murphy, E.P., Veale, D., Bresnihan, B., FitzGerald, O.; (2005) Alternative splicing of the VEGFR-1 (flt-1) and its ligands in human inflammatory arthritis ARTHRITIS AND RHEUMATISM , pp.S52-S52 38 [Details]
Sweeney, C., Cahill, P.A., Mullan, R., Connolly, M., Bresnihan, B., FitzGerald, O., Fearon, U. Veale, D.J.; (2005) A role for the survivin and notch signalling pathways in blood vessel maturation and synovial hyperplasia in RA American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Gogarty, M., Murphy, E., Veale, D.J., Bresnihan, B. FitzGerald, O.; (2005) Alternative splicing of the VEGFR-1 (flt-1) and its ligands in human inflammatory arthritis American Colelge of Rheumatology AGM [Details]
Bresnihan, B,Baeten, D,Firestein, GS,Fitzgerald, OM,Gerlag, DM,Haringman, JJ,McInnes, IB,Reece, RJ,Smith, MD,Ulfgren, AK,Veale, DJ,Tak, PP (2005) JOURNAL OF RHEUMATOLOGY Synovial tissue analysis in clinical trials , pp.2481-2484 [Details]
Mullan, R., Bresnihan, B., Sweeney, C., Connolly, M., FitzGerald, O., Veale, D. Fearon, U.; (2005) A novel role for the HDL receptor CLA-1 in synovial inflammation through serum amyloid A and apoprotein A-1 American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
   

Editorial

Harty, L,Veale, DJ (2010) How early should psoriatic arthritis be treated with a TNF-blocker?. Editorial [DOI] [Details]
                 

Abstract

Minnock, P,McKee, G,Bresnihan, B,FitzGerald, O,Veale, D (2012) Fatigue in patients with rheumatoid arthritis: examination of contributory factors post tumor necrosing factor inhibitor treatment. Abstract [Details]
McGarry, T,Connolly, M,McCormick, J,Gao, W,Veale, DJ,Fearon, U (2012) Beta 1 INTEGRIN MEDIATES TOLL-LIKE RECEPTOR 2 INDUCED MIGRATION AND INVASION VIA RAC1 ACTIVATION. Abstract [DOI] [Details]
Gilmore, A,Marzaioli, V,McMorrow, JP,Angerer, H,Crean, D,Zocco, D,Rooney, P,Veale, D,Fearon, U,Gogarty, M,McEvoy, AN,Stradner, MH,Murphy, EP (2012) HISTAMINE CONTRIBUTES TO AN INCREASED RANKL/OPG RATIO THROUGH ALTERED NR4A ACTIVITY IN HUMAN CHONDROCYTE CELLS. Abstract [Details]
Reid, A,Brady, A,Cusack, T,Blake, C,Mongey, AB,Veale, DJ,FitzGerald, O (2009) RCT EXAMINING THE EFFECTS OF EXERCISE FOR PEOPLE WITH RHEUMATOID ARTHRITIS ON ANTI-TNF alpha MEDICATION. Abstract [Details]
O'Rourke, M,FitzGerald, O,Bresnihan, B,Veale, D (2007) Psoriatic arthritis: Patient knowledge and its relationship to quality of life. Abstract [Details]
Brulhart, L,Ng, CT,Codd, MB,Walsh, CAE,Pontifex, EK,Lynch, B,Grier, A,Molloy, M,O'Flynn, E,Bresnihan, B,FitzGerald, O,Veale, DJ (2007) Co-medication with methotrexate is not associated with remission in psoriatic arthritis patients on TNFI inhibitors treatment. Abstract [Details]
Connolly, M,McCormick, J,Mullan, R,Fitzgerald, O,Bresnihan, B,Veale, D,Fearon, U (2007) A-SAA upregulates chemokine expression, MMP production and GAG release in inflammatory arthritis. Abstract [Details]
Walsh, CAE,FitzGerald, O,Veale, DJ,Golden-Mason, L,Bresnihan, B,Fearon, U (2007) Expansion of synovial fluid CD56 bright NKT cells in inflammatory arthritis associated with increased cytotoxicity and inflammatory cytokine production. Abstract [Details]
Kennedy, A,Sweeney, C,Walshe, T,Cahill, PA,Bresnihan, B,Fitzgerald, O,Fearon, U,Veale, DJ (2007) Regulation of VEGF and angiopoietins in inflammatory arthritis. Abstract [Details]
Gogarty, M,Murphy, EP,Fearon, U,Veale, DJ,Bresnihan, B,FitzGerald, O (2007) Placenta growth factor (PLGF) expression in inflammatory arthritis. Abstract [Details]
Gogarty, M,Murphy, EP,Fearon, U,Veale, DJ,Bresnihan, B,FitzGerald, O (2007) Abundant placenta growth factor (PlGF) expression in the inflammatory joint. Abstract [Details]
Pontifex, E,Gogarty, M,Murphy, E,Bresnihan, B,Veale, D,FitzGerald, O (2006) JunB expression in psoriatic arthritis synovium and skin pre- and post-treatment with etanercept. Abstract [Details]
Mullan, RH,Fearon, U,Mathews, C,Lobanok, T,King, L,FitzGerald, O,Bresnihan, B,Poole, R,Veale, DJ (2006) Serum amyloids a (A-SAA) correlates with joint damage in vivo and induces cartilage matrix degradation in vitro. Abstract [Details]
Gogarty, M,Murphy, E,Veale, D,Bresnihan, B,Fitzgerald, O (2005) Alternative splicing of the VEGFR-1 (flt-1) and its ligands in human inflammatory arthritis. Abstract [Details]
Mullan, RH,Lobanok, T,Walsh, C,King, L,FitzGerald, O,Bresnihan, B,Fearon, U,Poole, R,Veale, DJ (2005) The value of serum type II collagen epitope measurement in assessing early clinical response to treatment with anti-tumour necrosis factor alpha therapy in rheumatoid arthritis. Abstract [DOI] [Details]
O'Kane, M,Kirby, B,Fitzgerald, O,Veale, D,Markham, T,Murphy, E (2004) Corticotropin-releasing hormone - a possible role in psoriasis. Abstract [Details]
Mullan, RH,Golden-Mason, L,Markham, T,O'Hara, R,FitzGerald, O,Bresnihan, B,Veale, DJ,Fearon, U (2004) Acute-phase serum amyloid a stimulates angiogenesis, leukocyte recruitment and matrix degradation in RA via NF kappa B and MAPK-dependent pathways. Abstract [Details]
Mullan, RH,Lobanok, T,Walsh, E,King, L,FitzGerald, O,Bresnihan, B,Fearon, U,Poole, R,Veale, DJ (2004) The value of serum type II collagen epitope measurement in assessing early clinical response to treatment with anti-TNF-alpha therapy in rheumatoid arthritis. Abstract [Details]
Duffy, TN,Fearon, U,Godson, C,Brady, H,Bresnihan, B,Veale, D,FitzGerald, O (2003) Profibrotic mRNA is preferentially expressed in bone forming arthritis. Abstract [Details]
Mullan, RH,Mason, LG,Markham, T,O'Hara, R,FitzGerald, O,Bresnihan, B,Veale, DJ,Fearon, U (2003) A novel role for serum Amyloid-A (A-SAA) in angiogenesis and adhesion molecule expression through an NF kappa B-dependent signal transduction pathway. Abstract [Details]
Youssef, PP,Breedveld, FC,Bresnihan, B,Cassidy, N,Cunnane, G,Emery, P,FitzGerald, O,Kane, D,Kraan, M,Lindblad, S,Reece, R,Veale, D,Tak, PP (1997) Quantitative microscopic analysis of inflammation in rheumatoid arthritis synovial membrane samples selected at arthroscopy compared with samples taken blindly by needle biopsy. Abstract [Details]
                                                       

Articles

Collins, E; Butt, A; Gibson, D; Dunn, M; Fearon, U; van Kuijk, A; Gerlag, D; Pontifex, E; Veale, D, Tak, P; FitzGerald, O; Pennington, S (2015) A clinically based protein discovery strategy to identify potential biomarkers of response to anti-TNF-α treatment of psoriatic arthritis. Articles [Details]
     

Research

Research Interests


Professor Veale has established an international reknowned translational research group in the areas of pathogenesis, biopharmaceuticals and biomarkers in inflammation, early arthritis and autoimmunity. The basic science focus of the group is on hypoxia and metabolism, angiogenesis and cytokine signalling of inflammation.

The research team including senior scientists, post-doctoral scientists, clinical research fellows and PhD students funded by peer-reviewed grants from The European Union FP6 and FP7 Innovative Medicines Initiative (IMI), The Health Research Board of Ireland, Science Foundation Ireland, the Programme for Research in Third Level Institutions ,The American Federation for Ageing Research and a several of industry partnership programmes.

The clinical programme has recently expanded to form a national network of Rheumatology research to include a National Biologics registry and Rheumatology biobank.

Funding:
JU IMI (Innovative medicines Initiative)
Heath Research Board of Ireland
IRCSET
SFI
Investigator Initiated Research Programmes - Pfizer, Jannsen, Roche

                      

Research Projects

Sponsor : Health Research Board (HRB)
Title : VEGF and angiopoietins synergistically regulate abnormal angiogenesis through notch/hedgehog signalling components in the inflammed joint
Start Date / End Date : 01-DEC-06 / 01-OCT-10
Sponsor : Health Research Board (HRB)
Title : Hypoxia induced mitochondrial signalling pathways in inflammatory arthritis
Start Date / End Date : 01-NOV-06 / 31-MAR-12
Sponsor : University College Dublin (UCD)
Title : Measurements of oxygen tension in vivo in inflammation and cancer
Start Date / End Date : 01-OCT-06 / 30-SEP-07
Sponsor : Cambridge Antibody Technology Ltd., UK
Title : Investigation of GM-CSF/GM-CSF receptor in rheumatoid arthritis and synovial explant cultures
Start Date / End Date : 01-NOV-05 / 30-JUN-07
Sponsor : Health Research Board (HRB)
Title : Angiogenic growth factors in psoriasis and the effect of Anti-THFalpha blockade
Start Date / End Date : 01-JUL-02 / 30-JUN-04
Sponsor : Health Research Board (HRB)
Title : Mechanistic effects and clinical applications for the acute phase protein serum amyloid A in Rheumatoid Arthritis
Start Date / End Date : 01-JUL-04 / 31-DEC-05
Sponsor : Health Research Board (HRB)
Title : Role of Angiopoietins in Inflammation
Start Date / End Date : 01-OCT-04 / 30-SEP-07
Sponsor : Glaxo Smith Kline, UK
Title : Novel Therapies in RA: proof of concept studies
Start Date / End Date : 01-FEB-06 / 31-JAN-12
Sponsor : Wyeth Pharmaceuticals Inc, Research Division, Pensylvania, USA
Title : Inflamatory arthritis
Start Date / End Date : 30-JAN-07 / 24-AUG-09
Sponsor : Health Research Board (HRB)
Title : Novel Cytokine Profile in Early Arthritis - Implications for Pathogenesis and Treatment
Start Date / End Date : 01-JUL-08 / 30-JUN-11
Sponsor : HEA/PRTLI Cycle 4 Grant
Title : IL-17 regulates cytoskeletal rearrangement and cell matrix interactions to promote cell migration and cartilage invasion in inflammatory arthritis.
Start Date / End Date : 01-SEP-08 / 31-AUG-12
Sponsor : Centocor
Title : Analysis of clinical outcome measures in patients with inflammatory arthritis
Start Date / End Date : 01-OCT-09 / 31-DEC-11
Sponsor : Academisch Medisch Centrum (AMC) at the Universiteit van Amsterdam (SPA)
Title : Spiral consortium
Start Date / End Date : 01-JUL-09 / 31-JAN-12
Sponsor : Meteor Foundation
Title : Rheumatology project
Start Date / End Date : 01-APR-09 / 31-JAN-14
Sponsor : American Federation for Aging Research (AFAR)
University College Dublin (UCD)
Title : Acute Phase Serum Amyloid-A (A-SAA) in ageing, arthritis and obesity - potential common mechanism for cardiovascular disease
Start Date / End Date : 01-JUL-09 / 31-DEC-12
Sponsor : University College Dublin Foundation Ltd.
Title : Newman Fellowship in Inflammatory Arthritis
Start Date / End Date : 01-DEC-10 / 30-NOV-12
Sponsor : University College Dublin (UCD)
Innovative Medicines Initiative Joint Undertaking (IMI JU)
Title : BTCure
Start Date / End Date : 01-APR-11 / 31-MAR-17
Sponsor : Higher Education Authority (HEA)
Title : PRTLI 5: MMI
Start Date / End Date : 01-MAR-11 / 30-SEP-16
Sponsor : Meteor Foundation
Title : METEOR DATABASE MERGER
Start Date / End Date : 05-SEP-11 / 04-SEP-12
Sponsor : Pfizer Ltd., Ireland
Title : To examine the effect of Tofacitinib on pro-inflammatory pathways in RA MTX nonresponder patients
Start Date / End Date : 31-MAR-14 / 30-NOV-15
Sponsor : Health Research Board (HRB)
Title : 'Does hypoxia induced vascular dysfunction and Notch signaling alter response to anti-TNF therapy in Inflammatory Arthritis'
Start Date / End Date : 17-SEP-12 / 16-SEP-15
Sponsor : Health Research Board (HRB)
Title : Redox regulation of angiogenesis and innate immunity in inflammatory arthritis
Start Date / End Date : 01-OCT-13 / 31-DEC-16
Sponsor : University College Dublin (UCD)
Title : School funded research account
Start Date / End Date : 01-NOV-14 / 31-OCT-17
 

Current Postgraduate Students

Monika Biniecka, Graduate Certificate   -   Thesis Supervisor
Sarah Wade, Doctor of Philosophy (PhD)   -   Thesis Supervisor
Carl Orr, Doctor of Philosophy (PhD)   -   Thesis Supervisor

Teaching

Teaching Philosophy

I  represent the clinical staff on the Postgraduate Degree Committee, UCD and

    actively participate in teaching of Pre-clinical students at the HSB UCD, and clinical 4th and final year students at SVUH.  I also provide regular undergraduate and postgraduate lectures and tutorials in the SMMS. 


I actively teach in a number of postgraduate programmes including the degree course and the Masters Course for Translational Research. I also teach on the Research Frontiers course for basic science PhD's. I teach on the Immunology course in Trinity College Dublin.

 

I am the editor of the Rheumatology section of E-medicine, an exciting new web-based learning tool. 

 

I have led and developed a number of teaching programmes for medical, allied staff and unique patient education projects e.g. Patient Partners Programme and outreach lecture series.

 

I was National Specialty Director (2003-06) responsible for post-graduate Rheumatology SpR recruitment, training and appraisal. During this term I introduced a new training programme which the fellows attended 5-6 themed seminars each year, this included national and international lecturers, in addition to case presentations and discussions