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Researchers at UCD

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Eoin O'Brien

Adjunct Professor of Molecular Pharmacology

Conway Institute of Biomolecular & Biomedical Research
UCD
Belfield
Dublin 4

Tel: 353 1 2803865/ 353 1 2803688
Email: profeobrien@icloud.com

Biography

Eoin O'Brien has published over 800 scientific papers on hypertension research and has co-authored the popular ABC of Hypertension, the sixth edition of which will be published shortly by the British Medical Journal. Prof. O'Brien has been a principal investigator in a number of international studies. He is a Fellow of the Royal Colleges of Physicians of London and Edinburgh and serves in an administrative capacity with a number of national and international bodies concerned with the global management of cardiovascular disease. Prof. O'Brien sits on the editorial boards of a number of scientific journals devoted to hypertension and he is a past editor of the Irish Medical Journal and the Journal of the Irish Colleges of Physicians and Surgeons. In addition, Prof. O'Brien has established the website Medaval.org, which is devoted to presenting accuracy and performance data on devices for cardiovascular measurement. Together with Professor Neil Poulter, he has developed a smartphone application, entitled 'BP Expert', which allows patients with high blood pressure and those interested in their cardiovascular health to learn more about these topics.

I have been cardiologist and physician to a number of Dublin hospitals which include Beaumont Hospital, St. Laurence's Hospital, The Charitable Infirmary, The Rotunda Hospital, The City of Dublin Skin and Cancer Hospital and Connolly Hospital. Since retiring from Beaumont Hospital in 2004 I have conducted research from The Conway Institute in UCD. 

QUALIFICATIONS and DEGREES:
Licentiate of The Royal College of Physicians and Surgeons of Ireland.
LRCP & SI June 1963
Membership of The Royal College of Physicians of Ireland.
MRCP (IRL) March 1971
Membership of The Royal College of Physicians of London.
MRCP (UK) April 1971
Fellowship of The Royal College of Physicians of Ireland.
FRCP (IRL) June 1975
Fellowship of The Royal College of Physicians of London.
FRCP (UK) November 1982
Doctorate of Medicine, National University of Ireland.
MD December 1983
Fellowship of the Royal College of Physicians of Edinburgh.
FRCP (Edin) November 1993
Doctorate of Science DSc (NUI) November 2006

Professional

 

Associations

Association: Irish Skin Foundation, Function/Role: Executive Chairman
       

Committees

Committee : European Society of Hypertension, Working Group on Blood Pressure Monitoring and Cardiovascular Variability
Committee : Advisory Board, Medaval. Ireland
Committee : Centre for International Health and Cooperation, Fordham University, New York
Committee : Steering Committee. Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)
Committee : Steering Committee. TOPH (Home Pressure and Treatment of Hypertension) Study
Committee : CEN/TC205 EEC Committee for Non-active medical devices
Committee : Steering Committee of the European Multicentre Study of Systolic Hypertension in the Elderly (Syst-Eur Study)
Committee : Life Governor of the Dublin Skin and Cancer Hospital
Committee : Life Governor of the Charitable Infirmary
Committee : European Working Party for the Study of Hypertension in the Elderly
Committee : Sub-study Committee, Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)
Committee : Blood Pressure Standards Committee, The British Standards Institute
Committee : Council on High Blood Pressure. Irish Heart Foundation
Committee : WHO Committee for Blood Pressure Measurement in Low Resource Settings, Geneva

Employment

Employer: Irish Heart Foundation
Position: President
Employer: Conway Institute of Biomolecular and Biomedical Research, UCD
Position: Professor of Molecular Pharmacology

Education

Year 1963 Institution: Royal College of Surgeons in Ireland, Dublin.
Qualification: BA (Hons.) Subject: Physics, Medicine, Pathology, Midwifery and Gynaecology
     

Journals Edited

High Blood Pressure And Cardiovascular Prevention: Reviewer.
Blood Pressure Monitoring: Editorial Board member.
Hypertension: Editorial Board member.
Journal Of Clinical Hypertension: Reviewer.
Blood Pressure Monitoring: Reviewer.
Blood Pressure: Reviewer.
The Recorder: Editorial Board member.
Journal Of Human Hypertension: Reviewer.
Journal Of Hypertension: Reviewer.
Hypertension: Reviewer.
British Medical Journal: Reviewer.
Lancet: Reviewer.
 

Publications

Books

O'Brien Eoin; (2011) A Century of Service: The City of Dublin Skin and Cancer Hospital 1911 - 2011. Dublin: Anniversary Press. Dublin. [Details]

Book Chapters

O'Brien E; (2009) 'Assessment of the circadian cardiovascular risk with ambulatory blood pressure measurement' In: Giuseeppe Mancia (eds). Manual of Hypertension of the ESH. London: Informa Healthcare. , pp.48-50 [Details]
 

Peer Reviewed Journals

Campbell NR, Gelfer M;Stergiou GS;Alpert BS;Myers MG;Rakotz MK;Padwal R;Schutte AE;O'Brien E; ; (2016) 'A Call to Regulate Manufacture and Marketing of Blood Pressure Devices and Cuffs: A Position Statement From the World Hypertension League, International Society of Hypertension and Supporting Hypertension Organizations'. Journal of Clinical Hypertension, . [DOI] [Details]
Odili AN, Thijs L;Hara A;Wei FF;Ogedengbe JO;Nwegbu MM;Aparicio LS;Asayama K;Niiranen TJ;Boggia J;Luzardo L;Jacobs L;Stergiou GS;Johansson JK;Ohkubo T;Jula AM;Imai Y;O'Brien E;Staessen JA; (2016) 'Prevalence and Determinants of Masked Hypertension Among Black Nigerians Compared With a Reference Population'. Hypertension, 67 (6):1249-1255. [DOI] [Details]
Dolan E, O'Brien E (2016) 'Comparing the therapeutic merits of angiotensin receptor blockers'. Journal of Hypertension, 34 (6):1052-1054. [DOI] [Details]
Salles GF, Reboldi G;Fagard RH;Cardoso CR;Pierdomenico SD;Verdecchia P;Eguchi K;Kario K;Hoshide S;Polonia J;de la Sierra A;Hermida RC;Dolan E;O'Brien E;Roush GC (2016) 'Prognostic Effect of the Nocturnal Blood Pressure Fall in Hypertensive Patients: The Ambulatory Blood Pressure Collaboration in Patients With Hypertension (ABC-H) Meta-Analysis'. Hypertension, . [DOI] [Details]
O'Brien E, Dolan E;Atkins N (2015) 'Failure to Provide ABPM to All Hypertensive Patients Amounts to Medical Ineptitude'. Journal of Clinical Hypertension, 17 (6):462-465. [DOI] [Details]
Turner, R; O'Brien, E (2015) 'Inferences Beyond a Study Design¿s Grasp; A Cautionary Case Study From the Recent Renal Sympathetic Denervation Literature'. Therapeutic Innovation and Regulatory Science, 49 :86-92. [Details]
Draman MS, Dolan E;van der Poel L;Tun TK;McDermott JH;Sreenan S;O'Brien E (2015) 'The importance of night-time systolic blood pressure in diabetic patients: Dublin Outcome Study'. Journal of Hypertension, 33 (7):1373-1377. [DOI] [Details]
Kollias A, Rarra V;Karpettas N;Roussias L;O'Brien E;Stergiou GS (2015) 'Treatment-induced changes in ambulatory arterial stiffness index: one-year prospective study and meta-analysis of evidence'. Hypertension Research, 38 (9):627-631. [DOI] [Details]
Dolan E, O'Brien E (2015) 'Is It Daily, Monthly, or Yearly Blood Pressure Variability that Enhances Cardiovascular Risk?'. Current Cardiology Reports, 17 (11). [DOI] [Details]
O'Flynn AM, Dolan E;Curtin RJ;O'Brien E;Perry IJ;Kearney PM (2015) 'Night-time blood pressure and target organ damage: a comparative analysis of absolute blood pressure and dipping status'. Journal of Hypertension, 33 (11):2257-2264. [DOI] [Details]
O'Brien E (2015) 'Prognostic Value of Ambulatory Blood Pressure Monitoring in Obese Patients'. Journal of Clinical Hypertension, . [DOI] [Details]
Lee J, Chee Y;Kim I;Karpettas N;Kollias A;Atkins N;Stergiou GS;O'Brien E (2015) 'High-fidelity digital recording and playback sphygmomanometry system: device description and proof of concept'. Blood Pressure Monitoring, 20 (5):266-272. [DOI] [Details]
Asayama, K. and Thijs, L. and Li, Y. and Gu, Y.-M. and Hara, A. and Liu, Y.-P. and Zhang, Z. and Wei, F.-F. and Lujambio, I. and Mena, L.J. and Boggia, J. and Hansen, T.W. and Björklund-Bodegård, K. and Nomura, K. and Ohkubo, T. and Jeppesen, J. and Torp-Pedersen, C. and Dolan, E. and Stolarz-Skrzypek, K. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Luzardo, L. and Kawecka-Jaszcz, K. and Sandoya, E. and Filipovský, J. and Maestre, G.E. and Wang, J. and Imai, Y. and Franklin, S.S. and O'Brien, E. and Staessen, J.A. (2014) 'Setting thresholds to varying blood pressure monitoring intervals differentially affects risk estimates associated with white-coat and masked hypertension in the population'. Hypertension, . Available Online [DOI] [Details]
Li Y, Wei FF;Thijs L;Boggia J;Asayama K;Hansen TW;Kikuya M;Bj¿¿rklund-Bodeg¿¿rd K;Ohkubo T;Jeppesen J;Gu YM;Torp-Pedersen C;Dolan E;Liu YP;Kuznetsova T;Stolarz-Skrzypek K;Tikhonoff V;Malyutina S;Casiglia E;Nikitin Y;Lind L;Sandoya E;Kawecka-Jaszcz K;Mena L;Maestre GE;Filipovsk¿¿ J;Imai Y;O'Brien E;Wang JG;Staessen JA; (2014) 'Ambulatory hypertension subtypes and 24-hour systolic and diastolic blood pressure as distinct outcome predictors in 8341 untreated people recruited from 12 populations'. Circulation, 130 (6):466-474. [DOI] [Details]
McCarthy NS, Vangjeli C;Cavalleri GL;Delanty N;Shianna KV;Surendran P;O'Brien E;Munroe PB;Masca N;Tomaszewski M;Samani NJ;Stanton AV (2014) 'Two further blood pressure loci identified in ion channel genes with a gene-centric approach'. Circulation. Cardiovascular genetics, 7 (6):873-879. [DOI] [Details]
Modesti, P.A. and Agostoni, P. and Agyemang, C. and Basu, S. and Benetos, A. and Cappuccio, F.P. and Ceriello, A. and Del Prato, S. and Kalyesubula, R. and O'Brien, E. and Kilama, M.O. and Perlini, S. and Picano, E. and Reboldi, G. and Remuzzi, G. and Stuckler, D. and Twagirumukiza, M. and Van Bortel, L.M. and Watfa, G. and Zhao, D. and Parati, G. (2014) 'Cardiovascular risk assessment in low-resource settings: A consensus document of the European Society of Hypertension Working Group on Hypertension and Cardiovascular Risk in Low Resource Settings'. Journal of Hypertension, 32 (5):951-960. Available Online [DOI] [Details]
Gu, Y.-M. and Thijs, L. and Li, Y. and Asayama, K. and Boggia, J. and Hansen, T.W. and Liu, Y.-P. and Ohkubo, T. and Björklund-Bodegård, K. and Jeppesen, J. and Dolan, E. and Torp-Pedersen, C. and Kuznetsova, T. and Stolarz-Skrzypek, K. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Sandoya, E. and Kawecka-Jaszcz, K. and Imai, Y. and Mena, L.J. and Wang, J. and O'Brien, E. and Verhamme, P. and Filipovský, J. and Maestre, G.E. and Staessen, J.A. (2014) 'Erratum: Outcome-driven thresholds for ambulatory pulse pressure in 9938 participants recruited from 11 populations (Hypertension (2014) 63 (229-237))'. Hypertension, 63 (5):E128. Available Online [DOI] [Details]
Mena, L.J. and Maestre, G.E. and Hansen, T.W. and Thijs, L. and Liu, Y. and Boggia, J. and Li, Y. and Kikuya, M. and Björklund-Bodegard, K. and Ohkubo, T. and Jeppesen, J. and Torp-Pedersen, C. and Dolan, E. and Kuznetsova, T. and Stolarz-Skrzypek, K. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Sandoya, E. and Kawecka-Jaszcz, K. and Filipovsky, J. and Lmai, Y. and Wang, J. and O'Brien, E. and Staessen, J.A. (2014) 'How many measurements are needed to estimate blood pressure variability without loss of prognostic information?'. American Journal of Hypertension, 27 (1):46-55. Available Online [DOI] [Details]
Parati, G. and Stergiou, G. and O'Brien, E. and Asmar, R. and Beilin, L. and Bilo, G. and Clement, D. and De La Sierra, A. and De Leeuw, P. and Dolan, E. and Fagard, R. and Graves, J. and Head, G.A. and Imai, Y. and Kario, K. and Lurbe, E. and Mallion, J.-M. and Mancia, G. and Mengden, T. and Myers, M. and Ogedegbe, G. and Ohkubo, T. and Omboni, S. and Palatini, P. and Redon, J. and Ruilope, L.M. and Shennan, A. and Staessen, J.A. and Van Montfrans, G. and Verdecchia, P. and Waeber, B. and Wang, J. and Zanchetti, A. and Zhang, Y. (2014) 'European society of hypertension practice guidelines for ambulatory blood pressure monitoring'. Journal of Hypertension, 32 (7):1359-1366. Available Online [DOI] [Details]
Brguljan-Hitij, J. and Thijs, L. and Li, Y. and Hansen, T.W. and Boggia, J. and Liu, Y.-P. and Asayama, K. and Wei, F.-F. and Bjorklund-Bodegard, K. and Gu, Y.-M. and Ohkubo, T. and Jeppesen, J. and Torp-Pedersen, C. and Dolan, E. and Kuznetsova, T. and Katarzyna, S.-S. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Sandoya, E. and Kawecka-Jaszcz, K. and Filipovsky, J. and Imai, Y. and Wang, J. and O'Brien, E. and Staessen, J.A. (2014) 'Risk stratification by ambulatory blood pressure monitoring across JNC classes of conventional blood pressure'. American Journal of Hypertension, 27 (7):956-965. Available Online [DOI] [Details]
Hansen, T.W. and Thijs, L. and Li, Y. and Boggia, J. and Liu, Y. and Asayama, K. and Kikuya, M. and Björklund-Bodegard, K. and Ohkubo, T. and Jeppesen, J. and Torp-Pedersen, C. and Dolan, E. and Kuznetsova, T. and Stolarz-Skrzypek, K. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Sandoya, E. and Kawecka-Jaszcz, K. and Filipovský, J. and Imai, Y. and Wang, J. and O'Brien, E. and Staessen, J.A. (2014) 'Ambulatory blood pressure monitoring for risk stratification in obese and non-obese subjects from 10 populations'. Journal of Human Hypertension, 28 (9):535-542. Available Online [DOI] [Details]
Campbell, N.R.C. and Berbari, A.E. and Cloutier, L. and Gelfer, M. and Kenerson, J.G. and Khalsa, T.K. and Lackland, D.T. and Lemogoum, D. and Mangat, B.K. and Mohan, S. and Myers, M.G. and Niebylski, M.L. and O'Brien, E. and Stergiou, G.S. and Veiga, E.V. and Zhang, X.-H. (2014) 'Policy statement of the world hypertension league on noninvasive blood pressure measurement devices and blood pressure measurement in the clinical or community setting'. Journal of Clinical Hypertension, 16 (5):320-322. Available Online [DOI] [Details]
Li, Y. and Thijs, L. and Boggia, J. and Asayama, K. and Hansen, T.W. and Kikuya, M. and Björklund-Bodegård, K. and Ohkubo, T. and Jeppesen, J. and Torp-Pedersen, C. and Dolan, E. and Kuznetsova, T. and Stolarz-Skrzypek, K. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Sandoya, E. and Kawecka-Jaszcz, K. and Filipovský, J. and Imai, Y. and Ibsen, H. and O'Brien, E. and Wang, J. and Staessen, J.A. (2014) 'Blood pressure load does not add to ambulatory blood pressure level for cardiovascular risk stratification'. Hypertension, 63 (5):925-933. Available Online [DOI] [Details]
Barron, A.J. and Hughes, A.D. and Sharp, A. and Baksi, A.J. and Surendran, P. and Jabbour, R.J. and Stanton, A. and Poulter, N. and Fitzgerald, D. and Sever, P. and O'Brien, E. and Thom, S. and Mayet, J. (2014) 'Long-term antihypertensive treatment fails to improve E/e⿲ despite regression of left ventricular mass: An anglo-scandinavian cardiac outcomes trial substudy'. Hypertension, 63 (2):252-258. Available Online [DOI] [Details]
Gu, Y.-M. and Thijs, L. and Li, Y. and Asayama, K. and Boggia, J. and Hansen, T.W. and Liu, Y.-P. and Ohkubo, T. and Björklund-Bodegård, K. and Jeppesen, J. and Dolan, E. and Torp-Pedersen, C. and Kuznetsova, T. and Stolarz-Skrzypek, K. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Sandoya, E. and Kawecka-Jaszcz, K. and Imai, Y. and Mena, L.J. and Wang, J. and O'Brien, E. and Verhamme, P. and Filipovský, J. and Maestre, G.E. and Staessen, J.A. (2014) 'Outcome-driven thresholds for ambulatory pulse pressure in 9938 participants recruited from 11 populations'. Hypertension, 63 (2):229-237. Available Online [DOI] [Details]
Tragante, V. and Barnes, M.R. and Ganesh, S.K. and Lanktree, M.B. and Guo, W. and Franceschini, N. and Smith, E.N. and Johnson, T. and Holmes, M.V. and Padmanabhan, S. and Karczewski, K.J. and Almoguera, B. and Barnard, J. and Baumert, J. and Chang, Y.-P.C. and Elbers, C.C. and Farrall, M. and Fischer, M.E. and Gaunt, T.R. and Gho, J.M.I.H. and Gieger, C. and Goel, A. and Gong, Y. and Isaacs, A. and Kleber, M.E. and Leach, I.M. and McDonough, C.W. and Meijs, M.F.L. and Melander, O. and Nelson, C.P. and Nolte, I.M. and Pankratz, N. and Price, T.S. and Shaffer, J. and Shah, S. and Tomaszewski, M. and Van Der Most, P.J. and Van Iperen, E.P.A. and Vonk, J.M. and Witkowska, K. and Wong, C.O.L. and Zhang, L. and Beitelshees, A.L. and Berenson, G.S. and Bhatt, D.L. and Brown, M. and Burt, A. and (2014) 'Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci'. American Journal of Human Genetics, 94 (3):349-360. Available Online [Details]
Turner, J.R. and O'Brien, E. (2013) 'Diagnosis and Treatment of Resistant Hypertension: The Critical Role of Ambulatory Blood Pressure Monitoring'. Journal of Clinical Hypertension, 15 (12):868-873. Available Online [DOI] [Details]
Schutte R, Thijs L;Asayama K;Boggia J;Li Y;Hansen TW;Liu YP;Kikuya M;Bj¿¿rklund-Bodeg¿¿rd K;Ohkubo T;Jeppesen J;Torp-Pedersen C;Dolan E;Kuznetsova T;Stolarz-Skrzypek K;Tikhonoff V;Malyutina S;Casiglia E;Nikitin Y;Lind L;Sandoya E;Kawecka-Jaszcz K;Filipovsky J;Imai Y;Wang J;Ibsen H;O'Brien E;Staessen JA; (2013) 'Double product reflects the predictive power of systolic pressure in the general population: evidence from 9,937 participants'. American Journal of Hypertension, 26 (5):665-672. [DOI] [Details]
O'Brien, E. and Turner, J.R. (2013) 'Assessing Blood Pressure Responses to Noncardiovascular Drugs: The Beneficial Role of Ambulatory Blood Pressure Monitoring'. Journal of Clinical Hypertension, 15 (1):55-62. Available Online [DOI] [Details]
Boggia, J. and Thijs, L. and Li, Y. and Hansen, T.W. and Kikuya, M. and Björklund-Bodegård, K. and Ohkubo, T. and Jeppesen, J. and Torp-Pedersen, C. and Dolan, E. and Kuznetsova, T. and Stolarz-Skrzypek, K. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Schwedt, E. and Sandoya, E. and Kawecka-Jaszcz, K. and Filipovský, J. and Imai, Y. and Wang, J. and Ibsen, H. and O'Brien, E. and Staessen, J.A. (2013) 'Risk stratification by 24-hour ambulatory blood pressure and estimated glomerular filtration rate in 5322 subjects from 11 populations'. Hypertension, 61 (1):18-26. Available Online [DOI] [Details]
Franklin, S.S. and Thijs, L. and Li, Y. and Hansen, T.W. and Boggia, J. and Liu, Y. and Asayama, K. and Björklund-Bodegård, K. and Ohkubo, T. and Jeppesen, J. and Torp-Pedersen, C. and Dolan, E. and Kuznetsova, T. and Stolarz-Skrzypek, K. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Sandoya, E. and Kawecka-Jaszcz, K. and Filipovský, J. and Imai, Y. and Wang, J. and Ibsen, H. and O'Brien, E. and Staessen, J.A. (2013) 'Masked hypertension in diabetes mellitus: Treatment implications for clinical practice'. Hypertension, 61 (5):964-971. Available Online [DOI] [Details]
Persu, A. and Renkin, J. and Asayama, K. and O'Brien, E. and Staessen, J.A. (2013) 'Renal denervation in treatment-resistant hypertension: The need for restraint and more and better evidence'. Expert Review of Cardiovascular Therapy, 11 (6):739-749. Available Online [DOI] [Details]
Franklin, S.S. and Thijs, L. and Li, Y. and Hansen, T.W. and Boggia, J. and Liu, Y. and Asayama, K. and Björklund-Bodegård, K. and Ohkubo, T. and Jeppesen, J. and Torp-Pedersen, C. and Dolan, E. and Kuznetsova, T. and Stolarz-Skrzypek, K. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Sandoya, E. and Kawecka-Jaszcz, K. and Filipovský, J. and Imai, Y. and Wang, J. and Ibsen, H. and O'Brien, E. and Staessen, J.A. (2013) 'Response to masked hypertension in untreated and treated patients with diabetes mellitus: Attractive but questionable interpretations and response to is masked hypertension related to diabetes mellitus?'. Hypertension, . Available Online [DOI] [Details]
Franklin, S.S. and Thijs, L. and Hansen, T.W. and O'Brien, E. and Staessen, J.A. (2013) 'White-coat hypertension new insights from recent studies'. Hypertension, 62 (6):982-987. Available Online [DOI] [Details]
O'Brien, E. and Parati, G. and Stergiou, G. and Asmar, R. and Beilin, L. and Bilo, G. (2013) 'Erratum: European society of hypertension position paper on ambulatory blood pressure monitoring (Journal of Hypertension (2013) 31 (1731-1768))'. Journal of Hypertension, 31 (12):2467. Available Online [DOI] [Details]
Kollias, A. and Stergiou, G.S. and Dolan, E. and O'Brien, E. (2012) 'Ambulatory arterial stiffness index: A systematic review and meta-analysis'. Atherosclerosis, 224 (2):291-301. Available Online [DOI] [Details]
Stergiou, G.S. and Karpettas, N. and Atkins, N. and O'Brien, E. (2012) 'The European Society of Hypertension International Protocol for the validation of blood pressure measuring devices in adults. Response to letter by Gallick D., Friedman B.A., Alpert B.S., Seller J.D., Quinn D.E., and Osborn D'. Blood Pressure Monitoring, 17 (1):45-47. Available Online [DOI] [Details]
Franklin, S.S. and Thijs, L. and Hansen, T.W. and Li, Y. and Boggia, J. and Kikuya, M. and Björklund-Bodegård, K. and Ohkubo, T. and Jeppesen, J. and Torp-Pedersen, C. and Dolan, E. and Kuznetsova, T. and Stolarz-Skrzypek, K. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Sandoya, E. and Kawecka-Jaszcz, K. and Imai, Y. and Wang, J. and Ibsen, H. and O'Brien, E. and Staessen, J.A. (2012) 'Significance of white-coat hypertension in older persons with isolated systolic hypertension: A meta-analysis using the international database on ambulatory blood pressure monitoring in relation to cardiovascular outcomes population'. Hypertension, 59 (3):564-571. Available Online [DOI] [Details]
Stergiou, G.S. and Parati, G. and Asmar, R. and O'Brien, E. (2012) 'Requirements for professional office blood pressure monitors'. Journal of Hypertension, 30 (3):537-542. Available Online [DOI] [Details]
Vellinga, A. and Murphy, A. and O'Brien, E. (2012) 'Thirty-minute compared to standardised office blood pressure measurement in general practice'. British Journal of General Practice, 62 (596):126. Available Online [DOI] [Details]
Johnson, T. and Gaunt, T.R. and Newhouse, S.J. and Padmanabhan, S. and Tomaszewski, M. and Kumari, M. and Morris, R.W. and Tzoulaki, I. and O'Brien, E.T. and Poulter, N.R. and Sever, P. and Shields, D.C. and Thom, S. and Wannamethee, S.G. and Whincup, P.H. and Brown, M.J. and Connell, J.M. and Dobson, R.J. and Howard, P.J. and Mein, C.A. and Onipinla, A. and Shaw-Hawkins, S. and Zhang, Y. and Smith, G.D. and Day, I.N.M. and Lawlor, D.A. and Goodall, A.H. and Fowkes, F.G. and Abecasis, G.R. and Elliott, P. and Gateva, V. and Braund, P.S. and Burton, P.R. and Nelson, C.P. and Tobin, M.D. and Van Der Harst, P. and Glorioso, N. and Neuvrith, H. and Salvi, E. and Staessen, J.A. and Stucchi, A. and Devos, N. and Jeunemaitre, X. and Plouin, P.-F. and Tichet, J. and Juhanson, P. and Org, E. and Pu (2011) 'Blood pressure loci identified with a gene-centric array'. American Journal of Human Genetics, 89 (6):688-700. Available Online [DOI] [Details]
O'Brien, E. and Parati, G. (2011) 'Reverting to simplicity: Palpating SBP'. Journal of Hypertension, 29 (1):27-28. Available Online [DOI] [Details]
Kikuya, M. and Staessen, J.A. and Ohkubo, T. and Thijs, L. and Asayama, K. and Satoh, M. and Hashimoto, T. and Hirose, T. and Metoki, H. and Obara, T. and Inoue, R. and Li, Y. and Dolan, E. and Hoshi, H. and Totsune, K. and Satoh, H. and Wang, J.-G. and O'Brien, E. and Imai, Y. (2011) 'How many measurements are needed to provide reliable information in terms of the ambulatory arterial stiffness index the Ohasama study'. Hypertension Research, 34 (3):314-318. Available Online [DOI] [Details]
Boggia, J. and Thijs, L. and Hansen, T.W. and Li, Y. and Kikuya, M. and Björklund-Bodegård, K. and Richart, T. and Ohkubo, T. and Jeppesen, J. and Torp-Pedersen, C. and Dolan, E. and Kuznetsova, T. and Olszanecka, A. and Tikhonoff, V. and Malyutina, S. and Casiglia, E. and Nikitin, Y. and Lind, L. and Maestre, G. and Sandoya, E. and Kawecka-Jaszcz, K. and Imai, Y. and Wang, J. and Ibsen, H. and O'Brien, E. and Staessen, J.A. (2011) 'Ambulatory blood pressure monitoring in 9357 subjects from 11 populations highlights missed opportunities for cardiovascular prevention in women'. Hypertension, 57 (3):397-405. Available Online [DOI] [Details]
Jin, Y. and Thijs, L. and Richart, T. and Li, Y. and Dolan, E. and Wang, J.-G. and Protogerou, A. and O'Brien, E. and Staessen, J.A. and Safar, M.E. (2011) 'Responses of the ambulatory arterial stiffness index and other measures of arterial function to antihypertensive drugs'. Hypertension Research, 34 (4):489-495. Available Online [DOI] [Details]
Stergiou, G.S. and Karpettas, N. and Atkins, N. and O'Brien, E. (2011) 'Impact of applying the more stringent validation criteria of the revised European Society of Hypertension International Protocol 2010 on earlier validation studies'. Blood Pressure Monitoring, 16 (2):67-73. Available Online [DOI] [Details]
O'Brien, E. (2011) 'Reply to Dr Stockbridge'. Drug Information Journal, 45 (5):567-568. Available Online [DOI] [Details]
Rothwell, P. M.,Howard, S. C.,Dolan, E.,O'Brien, E.,Dobson, J. E.,Dahlof, B.,Sever, P. S.,Poulter, N. R.; (2010) 'Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension'. Lancet, 375 (9718):895-905. [Details]
Thijs L,Richart T, de Leeuw PW, Kuznetsova T,Grodzicki T, Kawecka-Jaszcz K, O'Brien E,Redón J, Birkenhäger WH, Fagard R, Staessen JA.; (2010) 'Morbidity and mortality on combination versus monotherapy: a post-hoc analysis of the Systolic Hypertension in Europe trial'. Hypertension, . [Details]
Hansen, TW,Thijs, L,Li, Y,Boggia, J,Kikuya, M,Bjorklund-Bodegard, K,Richart, T,Ohkubo, T,Jeppesen, J,Torp-Pedersen, C,Dolan, E,Kuznetsova, T,Stolarz-Skrzypek, K,Tikhonoff, V,Malyutina, S,Casiglia, E,Nikitin, Y,Lind, L,Sandoya, E,Kawecka-Jaszcz, K,Imai, Y,Wang, JG,Ibsen, H,O'Brien, E,Staessen, JA,Int Database Ambulatory Blood Pres; (2010) 'Prognostic Value of Reading-to-Reading Blood Pressure Variability Over 24 Hours in 8938 Subjects From 11 Populations'. Hypertension, 55 :1049-419. [DOI] [Details]
McGowan N, Atkins N, O'Brien E, Padfield P.; (2010) 'Computerised reporting improves the clinical use of ambulatory blood pressure measurement'. Blood Press Monit, . [Details]
Stergiou G, Karpettas N, Atkins N, O'Brien E. European Society of Hypertension ; (2010) 'International Protocol for the validation of blood pressure monitors: A critical review of its application and rationale for revision'. Blood Press Monit, . [Details]
O'Brien E, Atkins N, , Stergiou G, Parati G, Asmar R, Imai Y,Wang J, Mengden T, Shennan A on behalf of the Working Group on Blood Pressure Monitoring of the European Society of Hypertension; (2010) 'European Society of Hypertension Internationa Protocol for the Validation of Blood Pressure Measuring Devices in Adults. 2010 Revision'. Blood Press Monit, . [Details]
O'Brien, E.; (2010) 'An endothelin antagonist for resistant hypertension'. Lancet, 375 (9715):636-636. [Details]
O'BrienE; (2009) 'Ambulatory blood pressure measurement is indispensable to good clinical practice'. Hipertensión y Riesgo Vascular, . [DOI] [Details]
Stettler, C.,Witt, N.,Tapp, R. J.,Thom, S.,Allemann, S.,Tillin, T.,Stanton, A.,O'Brien, E.,Poulter, N.,Gallimore, J. R.,Hughes, A. D.,Chaturvedi, N.; (2009) 'Serum Amyloid A, C-Reactive Protein, and Retinal Microvascular Changes in Hypertensive Diabetic and Nondiabetic Individuals An Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) substudy'. Diabetes Care, 32 (6):1098-1100. Available Online [Details]
Dolan, E.,Stanton, A. V.,Thom, S.,Caulfield, M.,Atkins, N.,McInnes, G.,Collier, D.,Dicker, P.,O'Brien, E.,ASCOT Investigators; (2009) 'Ambulatory blood pressure monitoring predicts cardiovascular events in treated hypertensive patients - an Anglo-Scandinavian cardiac outcomes trial substudy'. Journal of Hypertension, 27 (4):876-885. Available Online [Details]
Stanton AV, Dicker P, O'Brien ET; (2009) 'Aliskiren Monotherapy Results in the Greatest and the Least Blood Pressure Lowering in Patients With High- and Low-Baseline PRA Levels, Respectively'. American Journal of Hypertension, . [DOI] [Details]
Wizner, B.,Dechering, D. G.,Thijs, L.,Kuznetsova, T.,Richart, T.,Jin, Y.,Gasowski, J.,O'Brien, E.,Struijker-Boudier, H. A.,Grodzicki, T.,Staessen, J. A.; (2009) 'Conventional and 24-h ambulatory blood pressure an independent predictors of elastic arterial properties'. Blood Pressure Monitoring, 14 (1):12-19. Available Online [Details]
Thom, S.,Stettler, C.,Stanton, A.,Witt, N.,Tapp, R.,Chaturvedi, N.,Allemann, S.,Mayet, J.,Sever, P.,Poulter, N.,O'Brien, E.,Hughes, A.; (2009) 'Differential Effects of Antihypertensive Treatment on the Retinal Microcirculation An Anglo-Scandinavian Cardiac Outcomes Trial Substudy'. Hypertension, 54 (2):405-408. Available Online [Details]
Sharp ASP, Tapp RJ. Thom SA McG, Francis DP, Hughes AD, Stanton AV, Zambanini A, O'Brien E, Chaturvedi N, Lyons S, Byrd S, Poulter NR, Sever PS, Mayet J on behalf of the ASCOT Investigators; (2009) 'Tissue Doppler E/E' ratio is a powerful predictor of primary cardiac events in a hypertensive population: an ASCOT substudy'. European Heart Journal, . [DOI] [Details]
Manisty CH, Zambanini A, Parker KH, Davies JE, Francis DP, Mayet J, Thom SA McG, Hughes AD on behalf of the Anglo-Scandinavian Cardiac Outcome Trial Investigators; (2009) 'Differences in the Magnitude of Wave Reflection Account for Differential Effects of Amlodipine- Versus Atenolol-Based Regimens on Central Blood Pressure An Anglo-Scandinavian Cardiac Outcome Trial Substudy'. Hypertension, 54 (724-730). [Details]
Poulter NR, Dobson JE, Sever PS, Dahlöf B,Wedel H, Campbell NRCon behalf of the ASCOT Investigators; (2009) 'Baseline Heart Rate, Antihypertensive Treatment, and Prevention of Cardiovascular Outcomes in ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial)'. Journal of the American College of Cardiology, 54 (1154-1161). [Details]
Williams B, Lacy PS,Cruickshank JK, Collier D, Hughes AD, Stanton A, Thom S, Thurston H, for the CAFE and ASCOT Investigators; (2009) 'Impact of Statin Therapy on Central Aortic Pressures and Hemodynamics. Principal Results of the Conduit Artery Function Evaluation-Lipid-Lowering Arm (CAFE-LLA) Study'. Circulation, 119 (53-61). [Details]
Staessen JA, O'Brien E. ; (2008) 'Proceedings of a workshop of the European Society of Hypertension'. Blood Press Monit, :143-143. [Details]
Lia Y, Boggia J, Thijs L, Hansen TW, Kikuya M, Bjo rklund-Bodega rd K, Richart T, Ohkubo T, Kuznetsova T, Torp-Pedersen C, Lind L, Ibsen H, Imai Y, Wang J, Sandoya E, O'Brien E, Staessen JA, on behalf of the International Database on Ambulatory Blood Pressure Monitoring in relation to Cardiovascular Outcomes Investigators.; (2008) 'Is blood pressure during the night more predictive of cardiovascular outcome than during the day?'. Blood Press Monit, 13 :145-147. [Details]
Burr LM, Dolan E, O'Brien EW, O'Brien ET, McCormack P. ; (2008) 'The value of ambulatory blood pressure in older adults: the Dublin outcome study'. Age and Ageing, 37 :201-206. [Details]
Sever PS, Poulter NR, Dahlof B, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes G, Mehlsen J, Nieminen MS, O'Brien ET, Ostergren J on behalf of the ASCOT Investigators.; (2008) 'The Anglo-Scandinavian Cardiac Outcomes Trial: lipid lowering arm: extended observations 2 years after trial closure'. European Heart Journal, 29 :499-508. [Details]
O'Brien E.; (2008) 'Ambulatory Blood Pressure Measurement. The Case for Implementation in Primary Care'. Hypertension, 51 :1435-1441. [DOI] [Details]
Adiyaman AA, Dechering DG, Thien T, Boggia J, Hanssen TW, Li Y, Wang J-G, O'Brien E , Staessen JA. ; (2008) 'Putting a spin on the ambulatory arterial stiffness index'. Journal of Hypertension, 26 :1266-1269. [Details]
Ryan AW, O'Brien E, Shields D, McManus R. ; (2008) 'Lack of association between NFKBIL1/LTA polymorphisms and hypertension, myocardial infarct, unstable angina and stable angina in a large Irish population sample'. Atherosclerosis, 197 :465-466. Available Online [Details]
O'Brien E. ; (2007) 'Ambulatory Blood Pressure Measurement Should Be a Routine Investigation in Patients with Renal Disease'. European Renal Disease, :52-53. [Details]
Moore, N.,Dicker, P.,O'Brien, J. K.,Stojanovic, M.,Conroy, R. M.,Treumann, A.,O'Brien, E. T.,Fitzgerald, D.,Shields, D.,Stanton, A. V.; (2007) 'Renin gene polymorphisms and haplotypes, blood pressure, and responses to renin-angiotensin system inhibition'. Hypertension, 50 (2):340-7. [Details]
Dolan E, Staessen JA, O'Brien E.; (2007) 'Data from the Dublin outcome study'. Blood Press Monit, 21 :401-403. [Details]
O'Brien E, Atkins N.; (2007) 'State-of-the-market from the dableducational.org website'. Blood Press Monit, 21 :377-379. [Details]
Boggia J, Li Y, Thijs L, Hansen TW, Kikuya M, Björklund-Bodegård K, Richart T, Ohkubo T, Kuznetsova T, Torp Pedersen C, Lind L, Ibsen H, Imai Y, Wang J, Sandoya E, O'Brien E, Staessen JA; (2007) 'on behalf of the International Database on Ambulatory blood pressure monitoring in relation to Cardiovascular Outcomes (IDACO) Investigators. Prognostic accuracy of day versus night ambulatory blood pressure: a cohort study'. Lancet, 370 :1219-1229. [Details]
*; (2007) '1. 2007 Guidelines for the Management of Arterial Hypertension. The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)'. Hypertension, 25 :1105-1187. [Details]
Atkins N, O'Brien E. ; (2007) 'The DABL®Educational Trust device equivalence procedure'. Blood Press Monit, 12 :245-249. [Details]
O'Brien E, Barton J, Nussberger J, Mulcahy D, Jensen C, Dicker P, Stanton, A.; (2007) 'Aliskiren provides antihypertensive efficacy and suppression of plasma rennin activity in combination with a thiazide diuretic, an angiotensin converting enzyme inhibito, or an angiotensin receptor blocker'. Hypertension, 49 :276-284. [Details]
1. Kikuya M, Staessen JA, Ohkubo T, Thijs L, Metoki H, Asayama K, Obara T, Inoue R, Li Y, Dolan E, Hoshi H, Hashimoto J, Totsune K, Satoh H, Wang J-G, O'Brien E, Imai Y.; (2007) 'Ambulatory Arterial Stiffness Index and 24-Hour Ambulatory Pulse Pressure as Predictors of Mortality in Ohasama, Japan'. STROKE, 38 :1161-1166. [Details]
O'Brien, E.,Barton, J.,Nussberger, J.,Mulcahy, D.,Jensen, C.,Dicker, P.,Stanton, A.; (2007) 'Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker'. Hypertension, 49 (2):276-84. [Details]
Staessen, J. A.,O'Brien, E.; (2007) 'Progress in blood pressure measurement: a workshop of the European Society of Hypertension'. Blood Press Monit, 12 (4):243-4. [Details]
Staessen, J. A.,O'Brien, E.; (2007) 'Will generic hypertension guidelines reduce the proliferation of directives?'. Heart, 93 (7):775-7. [Details]
Thijs, L.,Hansen, T. W.,Kikuya, M.,Bjorklund-Bodegard, K.,Li, Y.,Dolan, E.,Tikhonoff, V.,Seidlerova, J.,Kuznetsova, T.,Stolarz, K.,Bianchi, M.,Richart, T.,Casiglia, E.,Malyutina, S.,Filipovsky, J.,Kawecka-Jaszcz, K.,Nikitin, Y.,Ohkubo, T.,Sandoya, E.,Wang, J.,Torp-Pedersen, C.,Lind, L.,Ibsen, H.,Imai, Y.,Staessen, J. A.,O'Brien, E.; (2007) 'The International Database of Ambulatory Blood Pressure in relation to Cardiovascular Outcome (IDACO): protocol and research perspectives'. Blood Press Monit, 12 (4):255-62. [Details]
O'Brien, E.; (2007) 'Sleepers versus nonsleepers: another twist to the dipper/nondipper concept'. Hypertension, 49 (4):769-70. [Details]
O'Brien, E., Cox, J. P., Fitzgerald, D. J., O'Malley, K.; (1989) 'Discrepancy between clinic and ambulatory blood pressure measurement in the evaluation of two antihypertensive agents'. J Hum Hypertens, 3 (4):259-62. [Details]
Fitzgerald, D. J., O'Callaghan, W. G., O'Brien, E., Johnson, H., Mulcahy, R., Hickey, N.; (1985) 'Home recording of blood pressure in the management of hypertension'. Irish Medical Journal, 78 (8):216-8. [Details]
O'Callaghan, W. G., Fitzgerald, D. J., O'Malley, K., O'Brien, E.; (1983) 'Accuracy of indirect blood pressure measurement in the elderly'. Br Med J (Clin Res Ed), 286 (6377):1545-6. [Details]
Burke, M. J., Towers, H. M., O'Malley, K., Fitzgerald, D. J., O'Brien, E. T.; (1982) 'Sphygmomanometers in hospital and family practice: problems and recommendations'. Br Med J (Clin Res Ed), 285 (6340):469-71. [Details]
Fitzgerald, D. J., O'Callaghan, W. G., McQuaid, R., O'Malley, K., O'Brien, E.; (1982) 'Accuracy and reliability of two indirect ambulatory blood pressure recorders: Remler M2000 and Cardiodyne Sphygmolog'. Br Heart J, 48 (6):572-9. [Details]
Fitzgerald, D. J., O'Callaghan, W. G., O'Malley, K., Horgan, J., O'Brien, E.; (1982) 'Clinical and haemodynamic responses to captopril and hydralazine in chronic congestive heart failure: the importance of preload reduction'. Br J Clin Pharmacol, 14 Suppl 2 :217S-222S. [Details]
Fitzgerald, D. J., O'Malley, K., O'Brien, E. T.; (1982) 'Inaccuracy of London School of Hygiene sphygmomanometer'. Br Med J (Clin Res Ed), 284 (6308):18-9. [Details]
Fitzgerald, D. J., O'Callaghan, W. G., O'Malley, K., O'Brien, E. T.; (1981) 'Accuracy of the London School of Hygiene and Remler M2000 sphygmomanometers'. Clin Sci (Lond), 61 Suppl 7 :399s-401s. [Details]
Fitzgerald, D. J., O'Malley, K., O'Brien, E. T.; (1981) 'Assessing automated blood pressure recorders'. Lancet, 2 (8253):993. [Details]

Other Journals

Turner, JR; O'Brien, E (2015) 'Inferences Beyond a Study Design's Grasp: A cautionary case study from the recent renal sympathetic denervation literature' Therapeutic Innovation and Regulatory Science 49 (1) :86-92. [Details]
O'Brien E.; (2008) 'CHD on the increase again: fact or fiction?' Medicine Weekly :36. [Details]
O'Brien E.; (2008) 'Cardiovascular mortality' Medicine Weekly :40. [Details]
O'Brien E.; (2008) 'Stroke prevention' Irish Nursing 16 (3) . [Details]
O'Brien E.; (2008) 'The disgrace of Ireland's blood pressure statistics' Irish Medical Times :27. [Details]

Conference Publications

Li, Y; Wang, JG; Dolan, E; O'Brien, E; Hansen, TW; Ibsen, H; Kikuya, M; Imai, Y; Richart, T; Thijs, L; Staessen, JA; ; (2007) HYPERTENSION Response to arterial stiffness index is not a stiffness parameter but a ventriculo-arterial coupling factor , pp.8-9 [Details]
Li, Y; Wang, JG; Dolan, E; O'Brien, E; Thijs, L; Nawrot, T; Staessen, JA; ; (2006) HYPERTENSION Response to correlating ambulatory blood pressure measurements with arterial stiffness: A conceptual inconsistency , pp.109-109 [Details]
O'Halloran, AM; Stanton, A; O'Brien, E; Shields, DC; ; (2006) ANNALS OF HUMAN GENETICS The impact on coronary artery disease of common polymorphisms known to modulate responses to pathogens , pp.934-945 [Details]
Dolan, C; Shields, DC; Stanton, A; O'Brien, E; Lambert, DM; O'Brien, JK; Treacy, EP; ; (2005) BMC MEDICAL GENETICS Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians [Details]
   

Editorial

O'Brien E (2016) Why Is It That We Continue to Deny Patients Ambulatory Blood Pressure Monitoring?. Editorial [DOI] [Details]
O'Brien E (2016) Why Is It So Difficult to Influence the Clinical Management of Hypertension?. Editorial [DOI] [Details]
O'Brien, E; (2011) Bahrain: continuing imprisonment of doctors. Editorial [DOI] [Details]
O'Brien, E; (2011) Why ABPM Should Be Mandatory in All Trials of Blood Pressure-Lowering Drugs. Editorial [Details]
O'Brien, E,Parati, G; (2011) Reverting to simplicity: palpating SBP. Editorial [DOI] [Details]
Dolan, E,O'Brien, E; (2010) Blood Pressure Variability Clarity for Clinical Practice. Editorial [DOI] [Details]
O'Brien, E,Stergiou, G; (2010) Who will bell the cat? A call for a new approach for validating blood pressure measuring devices. Editorial [DOI] [Details]
Stanton, AV,Dicker, P,O'Brien, ET; (2009) Aliskiren Monotherapy Results in the Greatest and the Least Blood Pressure Lowering in Patients With High- and Low-Baseline PRA Levels, Respectively. Editorial [DOI] [Details]
O'Brien E, Sever P.; (2009) Is systolic blood pressure all that matters? BMJ. Editorial [Details]
O'Brien, E; (2009) Dipping Comes of Age The Importance of Nocturnal Blood Pressure. Editorial [DOI] [Details]
O'Brien, E; (2009) Is systolic blood pressure all that matters? No. Editorial [DOI] [Details]
Staessen, JA,O'Brien, E; (2008) Proceedings of a workshop of the European Society of Hypertension. Editorial [Details]
O'Brien, E; (2007) Sleepers versus nonsleepers - Another twist to the dipper/nondipper concept. Editorial [DOI] [Details]
O'Brien, E; (2007) Is the case for ABPM as a routine investigation in clinical practice not overwhelming?. Editorial [DOI] [Details]
Staessen, JA,O'Brien, E; (2007) Will generic hypertension guidelines reduce the proliferation of directives?. Editorial [DOI] [Details]
Staessen, JA,O'Brien, E; (2007) Progress in blood pressure measurement: a workshop of the European Society of Hypertension. Editorial [Details]
O'Brien, E; (2006) Whither conventional blood pressure measurement?. Editorial [DOI] [Details]
O'Brien, E; (2006) Ambulatory blood pressure measurement - A trove of hidden gems?. Editorial [DOI] [Details]
 

Newspaper Articles

O'Brien, E (2015) Migrant Crisis. Newspaper Articles [Details]
O'Brien, E (2015) Freedoms at the heart of medical education. Newspaper Articles [Details]
O'Brien, E (2015) Renal denervation: update on a scientific debacle. Newspaper Articles [Details]
                     

Book Reviews

O'Brien, E (2015) Prose with shirts. The Crossdresser's Secret by Brian O'Doherty. Book Reviews [Details]
                                                 

Educational Articles

O'Brien E.; (2009) BP control not a reality for most. Cardiology Professional. Educational Articles [Details]
O'Brien E.; (2009) Has anything changed in the management of CD? Ir Med Times. Educational Articles [Details]
O'Brien E. ; (2009) ABPM in Primary Care. Irish Medical News Cardiology Supplement. Educational Articles [Details]
O'Brien E.; (2009) In memoriam. Thomas George Pickering. J Hypertens. Educational Articles [Details]
O'Brien E.; (2009) The value of patterns of 24-hour ABPM. Ir Med Times. Educational Articles [Details]
O'Brien E.; (2009) Cardiology Hypertension Module 144. Blood pressure control. Forum. Educational Articles [Details]
O'Brien E.; (2008) CHD on the increase again: fact or fiction? Medicine Weekly. Educational Articles [Details]
 

Letters

Dechering D, Adiyaman A,Thijs L, Li Y, Richart T,Hansen TW, Kikuya M, Wang J, O'Brien E, Thien T, Staessen JA.; (2009) Comments on the reproducibility of ambulatory arterial stiffness index and QRS Korotkoff delay index. J Hypertens. Letters [Details]
O'Brien E.; (2009) Renal sympathetic denervation for resistant hypertension. Lancet. Letters [Details]
O'Brien E. ; (2009) Global intercourse. Lancet. Letters [Details]
O'Brien E.; (2009) Home Blood Pressure Measurements Will or Will Not Replace Ambulatory Blood Pressure Measurement. Hypertension. Letters [Details]
Adiyaman A, Dechering D, Thien T, Boggia J, Li Y, Wang J-G, Hansen TW, O'Brien E, Richart T, Thijs L. Staessen JA.; (2009) Response to Determinants of the Ambulatory Arterial Stiffness Index Regression. Hypertension. Letters [Details]

Research

Research Interests

I founded the Blood Pressure Unit in 1979 in the Charitable Infirmary, Jervis Street in collaboration with Professor Kevin O'Malley. From the outset the Unit concentrated on research into the pharmacology of blood pressure lowering drugs, particularly in the elderly, and on the development of blood pressure measuring techniques, especially techniques of ambulatory blood pressure measurement.

The Arterial Disease Assessment Prevention and Treatment (ADAPT) Clinic was established in collaboration with Professor David Bouchier-Hayes and Professor Desmond Fitzgerald in Beaumont Hospital 1997. The rationale for this unique clinic was based on the concept that disease of the arterial organ was a fundamental denominator in all-cardiovascular disease. The ADAPT Clinic was established to ensure that all patients with cardiovascular disease, regardless of the speciality to which they presented, would receive the most comprehensive risk factor assessment with appropriate life-style modification and evidence-based drug treatment directed at the arterial organ.

The ADAPT concept was further developed in 1999 with the establishment of the ADAPT Centre, which became the research facility of the Blood Pressure Unit. The ADAPT Centre was committed to the emerging role of translational research in bridging the void between the clinical 'bedside' and the laboratory 'bench'. The ADAPT Centre provided out-patient facilities and a cardiovascular laboratory equipped to perform state-of-the-art cardiovascular assessment that included echocardiography, electrocardiography with stress testing, Holter monitoring, applanation tonometry, pulse wave velocity analysis, 24-hour ambulatory blood pressure monitoring, beat-to-beat non-invasive blood pressure monitoring, 24-hour silent ischaemia monitoring, fundal photography and imaging, and carotid wall (intima-media thickness) imaging. Through its association with the Charitable Infirmary Trust Molecular Medicine Laboratories and the Clinical Research Centre in the RCSI Building at Beaumont Hospital, and with the Department of Clinical Pharmacology, the Centre for Proteomics, SURGEN, and BIOSYS at RCSI, the ADAPT Centre was able to further translational research into the biochemical and genetic markers of risk, thrombosis, and endothelial damage.
Over its 27-year history some 600 papers were published in peer-reviewed journals together with numerous editorials, letters, books, book chapters, general and educational articles and abstracts, and scientific and educational presentations were made in many countries around the world.


UCD Medicine Research Group: Cardiology and Cardiovascular Disease