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James Jones

Full Professor of Anatomy

School Of Medicine
Health Sciences Centre
Belfield
Dublin 4

Tel: +353 1 7166622
Email: james.jones@ucd.ie

Biography

2012-present Professor of Anatomy, UCD
2002-2012 Senior Lecturer in Physiology UCD
2002  MD (NUI) by published work
1995-2002 College Lecturer Physiology UCD
1993-1995 Wellcome Trust Lectureship RFHSM London
1993  PhD University of London
1989-1990 Lecturer in Physiology University College Dublin
1989 BSc(Hons) Physiology First class honours University College Dublin
1987 MB BCh BAO University College Dublin

I am a neuroanatomist interested in autonomic control of the gastrointestinal tract and cardiorespiratory systems.  At present I am working collaboratively with colorectal surgeons on the neural control systems of defaecation and the anal canal. Our objective is to refine the medical devices that are used in cases of faecal incontinence. I also have an active research interest in 3D printing in Anatomy, artificial muscles and neural prosthetic interfaces.






Professional

Honours and Awards

Year: 1999.
Title: President's Teaching Grant
Year: 2005.
Title: Prize Lecture of the Physiological Society
Year: 2007.
Title: Research Prize of the American Society of Colon and Rectal Surgeons
Year: 2005.
Title: Michael De Burgh Daly prize lecture (The physiological society)
Year: 2002.
Title: UCD Presidents Research Award
Year: 1993.
Title: Young Investigator of the Year - DeCastro-Heymans-Neil Medal (International Soc for arterial chemoreception)

Associations

Association: Neuroscience, TCD, Function/Role: External Examiner
Association: Anatomy, University of Birmingham, Function/Role: External Examiner
Association: Physiology, UCC, Function/Role: External Examiner
       

Committees

Committee : Royal Academy of Medicine
Committee : Medical degrees committee 2
Committee : Staff student committee
Committee : History and archives committee of The Physiological Society

Employment

Employer: Sligo General Hospital
Position: House Officer
Employer: Mater Hospital Dublin
Position: House Officer
Employer: University College Dublin
Position: Medical Demonstrator
Employer: University College Dublin
Position: Assistant Lecturer
Employer: Royal Free School of Medicine
Position: Research Fellow
Employer: Royal Free Hospital School of Medicine
Position: Lecturership
Employer: University College Dublin
Position: Lecturer

Education

Year 2002 Institution: NUI
Qualification: MD Subject: Physiology
Year 1987 Institution: University College Dublin
Qualification: MB, BCh, BAO Subject:
Year 1993 Institution: University of London
Qualification: PhD Subject:
Year 1990 Institution: University College Dublin
Qualification: BSc Subject:
     

Journals Edited

Experimental Physiology: Editor.
Autonomic Neuroscience: Basic And Clinical: Editor.
Experimental Physiology: Editor.
Irish Journal Of Medical Science: Editor-in-Chief.

Other Activities

I was the external exmainer for BSc (Anatomy) in the University of Leeds (2005-08).
I am currently the external examiner for the BSc (Anatomy) degree at the
University of Birmingham Leeds (2015-15).
Senior ethical editor for The Journal of Physiology

Publications

 

Book Chapters

O'Connor ET, O'Halloran KD, Jones JF. (2012) 'Propranolol does not affect the hindlimb vasodilatation elicited by stimulation of superior laryngeal nerve paraganglia' In: O'Connor ET, O'Halloran KD, Jones JF. (eds). Adv Exp Med Biol. New York, Boston: Kluwer Academic/Plenum. [DOI] [Details]
Edge D, Bradford A, Jones JFX, O'Halloran KD; (2011) 'Chronic intermittent hypoxia alters rat genioglossus motor unit properties' In: Edge D, Bradford A, Jones JFX, O'Halloran KD; (eds). International Society for Arterial Chemoreception. [Details]
 

Peer Reviewed Journals

Evers J, Devane L;Carrington EV;Scott SM;Knowles CH;O'Connell PR;Jones JF (2016) 'Reversal of sensory deficit through sacral neuromodulation in an animal model of fecal incontinence'. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 28 (5):665-673. [DOI] [Details]
Devane LA, Evers J;Scott MS;Knowles CH;O'Connell P;Jones JF (2016) 'Acute lumbosacral nerve stimulation does not affect anorectal motor function in a rodent model'. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 28 (3):358-363. [DOI] [Details]
Carrington EV, Evers J;Scott SM;Knowles CH;O'Connell PR;Jones JF (2015) 'Mechanically evoked cortical potentials: A physiological approach to assessment of anorectal sensory pathways'. Journal of Neuroscience Methods, 256 :198-202. [DOI] [Details]
Power BJ, O'reilly G;Murphy R;Murphy KJ;Pickering M;Jones JF (2015) 'Normal nerve striations are altered in the trembler-J mouse, a model of Charcot-Marie-Tooth disease'. Muscle and Nerve, 51 (2):246-252. [DOI] [Details]
O'Reilly MK, Reese S, Herlihy T, Geoghegan T, Cantwell CP, Feeney RNM, Jones JFX (2015) 'Fabrication and assessment of 3D printed anatomical models of the lower limb for anatomical teaching and femoral vessel access training in medicine'. Anatomical sciences education, . [DOI] [Details]
Devane LA, Evers J;Jones JF;Ronan O'Connell P (2015) 'A review of sacral nerve stimulation parameters used in the treatment of faecal incontinence'. Surgeon, 13 (3):156-162. [DOI] [Details]
Soetan BK, O'Connell PR, Jones JF (2014) 'Behavioural studies of faecal continence in the rat'. Medicine, . [DOI] [Details]
Lucking EF, O'Halloran KD;Jones JF (2014) 'Increased cardiac output contributes to the development of chronic intermittent hypoxia-induced hypertension'. Experimental Physiology, 99 (10):1312-1324. [DOI] [Details]
Edge D, McDonald FB;Jones JF;Bradford A;O'Halloran KD (2014) 'Effect of chronic intermittent hypoxia on the reflex recruitment of the genioglossus during airway obstruction in the anesthetized rat'. Progress in Brain Research, 209 :147-168. [DOI] [Details]
Carrington EV, Evers J, Grossi U, Dinning PG, Scott SM, O'Connell PR, Jones JF, Knowles CH (2014) 'A systematic review of sacral nerve stimulation mechanisms in the treatment of fecal incontinence and constipation'. Neurogastroenterology and Motility, 26 (9):1222-1237. [DOI] [Details]
Evers J, Devane L, Carrington EV, Scott SM, Knowles CH, O'Connell PR, Jones JF (2014) 'Effects of stimulation frequency and intensity in sacral neuromodulation on anorectal inputs to the somatosensory cortex in an experimental model'. British Journal of Surgery, 101 (10):1317-1328. [DOI] [Details]
Power BJ, O'Reilly G, Murphy R, Murphy KJ, Pickering M, Jones JF (2014) 'Normal nerve striations are altered in the Trembler-J mouse, a model of'. Muscle & Nerve, . [Details]
Jones JF (2013) 'A bicentennial celebration of the birth of Claude Bernard'. Medicine, 182 (4). [DOI] [Details]
Jones JF (2013) 'The impact of impact factors and the ethics of publication'. Medicine, 182 (4). [DOI] [Details]
Carberry JC, McMorrow C, Bradford A, Jones JF, O'Halloran KD (2013) 'Effects of sustained hypoxia on sternohyoid and diaphragm muscle during development'. EUR RESPIR J, . [DOI] [Details]
Skelly JR, Rowan SC, Jones JF, O'Halloran KD (2013) 'Upper airway dilator muscle weakness following intermittent and sustained hypoxia in the rat: effects of a superoxide scavenger'. Physiological research / Academia Scientiarum Bohemoslovaca, 62 (2):187-196. [Details]
Edge D, Bradford A, Jones JF, O'Halloran KD. (2012) 'Chronic intermittent hypoxia alters genioglossus motor unit discharge patterns in the anaesthetized rat'. Advances in experimental medicine and biology, . [DOI] [Details]
Skelly JR, Edge D, Shortt CM, Jones JF, Bradford A, O'Halloran KD (2012) 'Respiratory control and sternohyoid muscle structure and function in aged male rats: decreased susceptibility to chronic intermittent hypoxia'. Respiratory Physiology and Neurobiology, 180 (2-3):175-182. [DOI] [Details]
Griffin KM, O'Herlihy C, O'Connell PR, Jones JF (2012) 'Combined ischemic and neuropathic insult to the anal canal in an animal model of obstetric-related trauma'. Diseases of the Colon and Rectum, 55 (1):32-41. [DOI] [Details]
Buffini M, O'Halloran KD, O'Herlihy C, O'Connell PR, Jones JF (2012) 'Comparison of the motor discharge to the voluntary sphincters of continence in the rat'. Neurogastroenterology and Motility, 24 (4):1-84. [DOI] [Details]
O'Connor ET, O'Halloran KD, Jones JF (2012) 'Pro-inflammatory cytokines do not affect basal or hypoxia stimulated discharge of rat vagal paraganglia'. Experimental Physiology, . [DOI] [Details]
Evers J, Buffini M, Craven S, O'Connell R, Jones JF (2012) 'Is there a nitrergic modulation of the rat external anal sphincter?'. Experimental Physiology, . [DOI] [Details]
O'Connor ET, O'Halloran KD, Jones JF (2012) 'Propranolol does not affect the hindlimb vasodilatation elicited by stimulation of superior laryngeal nerve paraganglia'. Frontiers in Modeling and Control of Breathing, 758 :273-277. [DOI] [Details]
Edge D, Bradford A, Jones JF, O'Halloran KD (2012) 'Chronic intermittent hypoxia alters genioglossus motor unit discharge patterns in the anaesthetized rat'. Frontiers in Modeling and Control of Breathing, 758 :295-300. [DOI] [Details]
Jones JF (2012) 'Highlights in basic autonomic neurosciences: The vagus and the ventricles'. Autonomic Neuroscience: Basic and Clinical, 170 (1-2):1-2. [DOI] [Details]
McMorrow, C,Fredsted, A,Carberry, J,O'Connell, RA,Bradford, A,Jones, JFX,O'Halloran, KD; (2011) 'Chronic hypoxia increases rat diaphragm muscle endurance and sodium-potassium ATPase pump content'. European Respiratory Journal, 37 :1474-1481. [DOI] [Details]
Skelly JR, O'Connell RA, Jones JFX, O'Halloran KD; (2011) 'Structural and functional properties of an upper airway dilator muscle in aged obese male rats'. Respiration, . [Details]
Skelly JR, Edge D, Shortt CM, Jones JFX, Bradford A, O'Halloran KD; (2011) 'Tempol ameliorates pharyngeal dilator muscle dysfunction in a rodent model of chronic intermittent hypoxia'. American Journal of Respiratory Cell and Molecular Biology, . [Details]
Griffin KM, Pickering M, O'Herlihy C, O'Connell PR, Jones JF; (2011) 'Sacral nerve stimulation increases activation of the primary somatosensory cortex by anal canal stimulation in an experimental model'. British Journal of Surgery, 98 (8):1160-1169. [DOI] [Details]
Peirce C, O'Herlihy C, O'Connell PR, Jones JF; (2011) 'Effect of injury on S1 dorsal root ganglia in an experimental model of neuropathic faecal incontinence'. British Journal of Surgery, 98 (8):1155-1159. [DOI] [Details]
Buffini M, O'Halloran KD, O'Herlihy C, O'Connell R, Jones JF; (2010) 'Comparison of the contractile properties, oxidative capacities and fibre type profiles of the voluntary sphincters of continence in the rat'. Journal of Anatomy, 217 (3):187-195. [DOI] [Details]
Jones JF, Banahan M, Peirce C, Buffini M, O'Herlihy C, O'Connell PR, ; (2010) 'Atrophy of the sphincters of continence in an experimental model'. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, . [DOI] [Details]
Skelly JR, Bradford A, Jones JFX, O'Halloran KD; (2010) 'Superoxide scavengers improve rat pharyngeal dilator muscle performance'. American Journal of Respiratory Cell and Molecular Biology, 42 :725-731. [Details]
MacGrory B, O'Connor ET, O'Halloran KD, Jones JFX; (2010) 'Effects of pro-inflammatory cytokines on the discharge rate of vagal nerve paraganglia in the rat'. Respiratory Physiology & Neurobiology, 171 :122-127. [Details]
McMorrow C, Fredsted A, O'Connell RA, Carberry J, Bradford A, Jones JFX and O'Halloran KD; (2010) 'Chronic hypoxia increases rat diaphragm muscle endurance and Na+-K+ ATPase pump content'. European Respiratory Journal, 37 (6):1474-1481. [Details]
Peirce, C,Alexander, LE,O'Herlihy, C,O'Connell, PR,Jones, JFX; (2010) 'Central Representation of the Inferior Rectal Nerve of the Rat'. Diseases of the colon and rectum, 53 :315-320. [DOI] [Details]
Kelly, ME,Blau, CW,Griffin, KM,Gobbo, OL,Jones, JFX,Kerskens, CM; (2010) 'Quantitative functional magnetic resonance imaging of brain activity using bolus-tracking arterial spin labeling'. Blood, 30 :913-922. [DOI] [Details]
Griffin, KM,Blau, CW,Kelly, ME,O'Herlihy, C,O'Connell, PR,Jones, JFX,Kerskens, CM; (2010) 'Propofol allows precise quantitative arterial spin labelling functional magnetic resonance imaging in the rat'. Neuroimage, 51 (4):1395-1404. [DOI] [Details]
Jones JF, ; (2009) 'Cardiac defibrillator neurones'. Physiology, 587 (Pt 12). [DOI] [Details]
Jones JF, Peirce C, Healy CF, O'Herlihy C, O'Connell PR, ; (2009) 'Reduced somatosensory cortical activation in experimental models of neuropathic fecal incontinence'. Diseases of the Colon and Rectum, 52 (8):1417-1422. [DOI] [Details]
Jones JF, Healy CF, O'Herlihy C, O'Brien C, O'Connell PR, ; (2008) 'Experimental models of neuropathic fecal incontinence: an animal model of childbirth injury to the pudendal nerve and external anal sphincter'. Diseases of the Colon and Rectum, 11 (NA):1619-161. [DOI] [Details]
Jones JF, ; (2008) 'Adventures in pulmonary physiology: the action of drugs on the pulmonary circulation by Alcock, Berry & Daly (1935)'. Experimental Physiology, 3 (NA):316-318. [DOI] [Details]
Healy, C. F., McMorrow, C., O'Herlihy, C., O'Connell, P. R., Jones, J. F. X., ; (2008) 'External anal sphincter fatigue is not improved by N-acetylcysteine in an animal model'. Neurogastroenterology and Motility, 20 (6):719-724. [Details]
M Buffini, C O'Herlihy, PR O'Connell & JFX Jones ; (2008) 'Fatigability of isolated rat external urethral and anal sphincters'. IRISH JOURNAL OF MEDICAL SCIENCE, 177 (Suppl 11):S376-S377. [Details]
C. Peirce, C.F. Healy, C. O'Herlihy, P.R. O'Connell, J.F.X. Jones ; (2008) 'Peripheral and central effects of injury in rat models of neuropathic faecal incontinence'. Colorectal Disease, 10 (Suppl 1):4-4. [Details]
Jones JF, Peirce C, Healy CF, O'Herlihy C, O'Connell PR, ; (2008) 'Effect of prolonged vaginal distention and sphincter transection on physiologic function of the external anal sphincter in an animal model'. Obstetrics and Gynecology, 4 (NA):943-91. [DOI] [Details]
Sweeney, CM; Jones, JFX; Bund, SJ; ; (2007) 'Adrenoceptor and cholinoceptor modulation of rat pulmonary vein cardiac muscle contractility'. Vascular Pharmacology, 46 (3):166-170. [Details]
Pickering M, Jones JF.; (2007) 'Comparison of the motor discharge to the crural and costal diaphragm in the rat'. Respiratory Physiology & Neurobiology, 159 (1):21-27. [Details]
Jones JF, ; (2007) 'A moving-invisible-needle in a haystack experiment'. Experimental Physiology, 6 (NA). [DOI] [Details]
Pickering, M and Campion, D and Jones, JFX; (2004) 'A gastrointestinal role for the amphibian `diaphragm' of Xenopus laevis'. JOURNAL OF ZOOLOGY, 264 (Part 1):45-51. [Details]
O'Leary, DM; Murphy, A; Pickering, M; Jones, JFX; ; (2004) 'Arterial chemoreceptors in the superior laryngeal nerve of the rat'. Respiratory Physiology Neurobiology, 141 (2):137-144. [Details]
Jones, JFX,O'Leary, DM,Pickering, M; (2003) 'Vagal control of the cranial venae cavae of the rat heart'. Experimental Physiology, 88 :329-334. [Details]
O'Leary, DM; Jones, JFX; ; (2003) 'Peripheral chemoreceptor input to cardiac vagal preganglionic neurones in the anaesthetised rat'. Chemoreception: From Cellular Signalling to Functional Plasticity, 536 (NA):461-466. [Details]
O'Leary, DM,Jones, JFX; (2003) 'Discharge patterns of preganglionic neurones with axons in a cardiac vagal branch in the rat'. Experimental Physiology, 88 :711-723. [Details]
Hughes, K, Pickering, M, O'Leary, DM, Bradford, A, O'Regan, RG, Jones, JFX, ; (2003) 'The paraganglia of the rat superior laryngeal nerve'. Advances in Experimental Medicine and Biology, 536 (NA):239-246. [Details]
Pickering, M and Jones, JFX; (2002) 'The diaphragm: two physiological muscles in one'. JOURNAL OF ANATOMY, 201 (4):305-312. [Details]
Pickering, M,Campion, D,Jones, JFX; (2002) 'Reflex cardiorespiratory effects of nociceptive oesophageal distension in the decerebrate rat'. EXPERIMENTAL PHYSIOLOGY, 87 (NA):41-48. [Details]
Tak, HH; Jones, JFX; ; (2002) 'Vagal control of the rat cranial venae cavae'. Journal of Physiology, 539 (NA):104-105. [Details]
Jones JF, ; (2001) 'Vagal control of the rat heart'. Experimental Physiology, 6 (NA):797-801. [Details]
Al-Ghamdi, M.S.A.D., Jones, J.F.X. and Taylor, E.W.; (2001) 'Evidence of a functional role in lung inflation for the buccal pump in the agamid lizard Uromastyx aegyptius microlepis'. Journal of Experimental Biology, 204 :521-531. [Details]
Jones JF, ; (2000) 'Aortic body chemoreflex of the anaesthetized rat. Electrophysiological, morphological, and reflex studies'. Advances in Experimental Medicine and Biology, (NA):789-792. [Details]
Wang, Y; Jones, JFX; Jeggo, RD; Daly, MD; Jordan, D; Ramage, AG; ; (2000) 'Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats'. Journal of Physiology, 526 (1):157-165. [Details]
Brophy, S; Ford, TW; Carey, M; Jones, JFX; ; (1999) 'Activity of aortic chemoreceptors in the anaesthetized rat'. Journal of Physiology, 514 (3):821-828. [Details]
Jones, JFX, Wang, Y, Jordan, D, ; (1998) 'Activity of C fibre cardiac vagal efferents in anaesthetized cats and rats'. Journal of Physiology, 507 (3):869-880. [Details]
Jones, J.F.X., and Daly, M. de Burgh; (1997) 'Reflex cardiac dromotropic responses to stimulation of the carotid and aortic chemoreceptors in the anaesthetized cat'. Physiology, 502 :461-467. [Details]
Jones, J.F.X.,Wang,Y and Jordan, D.; (1995) 'The action of cardiac vagal C-fibres on heart rate in the anaesthetised cat, rat and rabbit'. Physiology, 489 :203-214. [Details]
Jones, J.F.X., Martin, G.R. and Ramage, A.G.; (1995) 'Evidence that 5-HT1D receptors mediate inhibition of sympathetic ganglionic transmission in anaesthetized cats'. British Journal of Pharmacology, 116 :1715-1717. [Details]
JONES, JFX, MCKEOGH, D, NOLAN, P, OREGAN, R, ; (1993) 'THE EFFECT OF ESOPHAGEAL DISTENSION ON DIAPHRAGM AND LARYNGEAL EMG IN THE ANESTHETIZED CAT'. Journal of Physiology, 467 (NA):151-151. [Details]

Other Journals

Kelly ME, Blau CW, Griffin KM, Gobbo OL, Jones JF, Kerskens CM.; (2010) 'Quantitative functional magnetic resonance imaging of brain activity using bolus-tracking arterial spin labeling' J Cereb Blood Flow Metab 30 (5) :913-922. [Details]
Peirce C, Alexander LE, Buffini, M. O'Herlihy C, O'Connell PR, Jones JF.; (2009) 'Investigation of the nerve supply to the external anal sphincter (EAS) in the female rat' British Journal of Surgery 96(S5) :37 . [Details]

Conference Publications

O'Connor T, O'Halloran KD, Jones JFX; (2011) Vagal paraganglia of the rat International Hypoxia Symposium (Lake Louise, Canada) [Details]
McMorrow C, Bradford A, Jones JFX, O'Halloran KD; (2011) Improved anoxic tolerance in chronic hypoxic rat diaphragm is nitric oxide dependent International Hypoxia Symposium (Lake Louise, Canada) [Details]
O'Connor T, O'Halloran KD, Jones JFX; (2010) The cardiorespiratory effects of stimulation of superior laryngeal nerve paraganglia in the urethane anaesthetised rat Physiological Society Themed Meeting (Birmingham): Proc Physiol Soc 20: C19 [Details]
McMorrow C, Fredsted A, Carberry J, O'Connell RA, Bradford A, Jones JFX, O'Halloran KD; (2010) Chronic hypoxia increases rat diaphragm muscle endurance and Na+-K+ ATPase pump content Physiological Society Main Meeting (Manchester) Proc Physiol Soc 19: PC26 [Details]
. T. O'Connor, K. D. O'Halloran, J. F. Jones. ; (2010) The Cardiorespiratory Reflex Effects of Stimulation of Superior Laryngeal Nerve Paraganglia in the Urethane Anaesthetised Rat J Physiol (2010) Proc Physiol Soc 20; C19 and PC19 Proc Physiol Soc [Details]
Kelly ME, Blau CW, Gobbo OL, Griffin KM, Jones JFX, Kerskens CM. ; (2010) Quantitative functional magnetic resonance imaging with bolus-tracking arterial spin labelling.Irish Journal of Medical Science 2010, Vol 179, supplement 3, S107-108 Irish Journal of Medical Science [Details]
O¿Connor ET, O¿Halloran KD, Jones JFX. ; (2010) The chemoreflex function of the superior laryngeal nerve paraganglia in the rat . In: Irish Journal of Medical Science 2010, Vol 179, Supplement 7S284 eds. Irish Journal of Medical Science [Details]
Peirce C, O¿Herlihy, C O¿Connell PR, Jones JFX. ; (2010) Faecal incontinence: where is the sense in it all? Irish Journal of Medical Science 2010, Vol 179, supplement 1, S1 Irish Journal of Medical Science 2010 [Details]
C. McMorrow, A. Fredsted, J. Carberry, R. O'Connell, A. Bradford, J. Jones, K. ; (2010) Chronic hypoxia increases rat diaphragm muscle endurance and Na+-K+ ATPase pump content Proc Physiol Soc [Details]
K. M. Griffin, C. O¿Herlihy, R. O¿Connell, J. Jones ; (2009) Brief sacral nerve root stimulation increases somatosensory cortical activation in the rat Proc Physiol Soc [Details]
M. Buffini, C. O'Herlihy, R. O'Connell, J. Jones ; (2009) Fibre size and oxidative capacity of the external anal and urethral sphincters Proc Physiol Soc [Details]
E. T. O'Connor, K. D. O'Halloran, J. Jones ; (2009) The Effect of IL-6 on the Hypoxic Sensitivity of Vagal Nerve Paraganglia in the Rat Proc Physiol Soc [Details]
Peirce C, Alexander LE, O'Herlihy C, O'Connell PR, Jones JFX; (2009) Activating transcription factor 3 (ATF-3) as a marker of injury in experimental models of neuropathic faecal Irish Journal of Medical Science [Details]
Pierce C, Alexander LE, Buffini, M. O'Herlihy C, O'Connell PR, Jones JF.; (2009) Investigation of the nerve supply to the external anal sphincter (EAS) in the female rat.96(S5) :37 British Journal of Surgery [Details]
J. F. Jones, C. Peirce, K. Griffin, M. Buffini, C. O'Herlihy, R. O'Connell; (2009) Animal models of neuropathic faecal incontinence Proc Physiol Soc [Details]
Holleran, L & Jones JFX; (2007) The sensitivity of isolated perfused laryngeal nerve fibres in the rat RAMI summer meeting [Details]
Healy, C.F., Jones, J.F.X., O'Brien, C., O'Herlihy, C. O'Connell, P.R.; (2006) The development of an acute animal model to simulate pelvic floor injury during childbirth The Society of Academic Research in Surgery [Details]
Healy, C.F., Jones, J.F.X., O'Brien, C., O'Herlihy, C. O'Connell, P.R.; (2006) The development of an acute animal model to simulate pelvic floor injury during childbirth Royal Academy of Medicine Ireland (RAMI) Winner of Registrar's Prize, Royal College of Surgeons [Details]
Healy, C.F., Jones, J.F.X., O'Brien, C., O'Herlihy, C. O'Connell, P.R.; (2006) The development of an acute animal model to simulate pelvic floor injury during childbirth The Association of Coloproctology of Great Britain and Ireland Annual Meeting [Details]
Healy, C.F., Jones, J.F.X, O'Brien, C., O'Herlihy, C. O'Connell, P.R.; (2006) The development of an acute animal model to simulate pelvic floor injury during childbirth Society of Coloproctology of Great Britain and Ireland [Details]
Jones, J.F.X., Shakespeare, I., Healy, C.F., Mitchell, P., Whealan, R., O'Herlihy, C. O'Connell, P.R.; (2005) Neural Control of rat external anal sphincter: a role for nitric oxide? Irish Society of Gastroenterology [Details]
   

Editorial

Jones, JFX; (2009) Cardiac defibrillator neurones. Editorial [DOI] [Details]
Jones, JFX; (2007) A moving-invisible-needle in a haystack experiment. Editorial [DOI] [Details]
                                                                                   

Research

Research Interests

My current funded research projects involve

 

1. Rat models of neuropathic faecal incontinence and the mechanism of action of sacral neuromodulation. In collaboration with Professor Ronan O'Connell I am examining the central nervous system re-arrangements that follow pudendal nerve injury. In addition, we are stimulating lumbosacral nerve roots in humans and rats to refine an emerging therapy for certain forms of faecal incontinence (SFI)

 

2. Atrial volume receptors in the heart funded by British Heart Foundation.

 

3. 3D printing of artificial muscles (funded by Seed funding UCD)

UCD Medicine Research Groups: Colorectal 

Research Projects

Sponsor : University College Dublin Foundation Ltd.
Title : UCD Foundation donation
Start Date / End Date : 01-MAR-16 / 28-FEB-18
Sponsor : University College Dublin Foundation Ltd.
Title : UCD Foundation donation
Start Date / End Date : 04-JAN-16 / 03-JAN-18
Sponsor : University College Dublin (UCD)
Title : Magnetic 3D-Printing
Start Date / End Date : 01-APR-16 / 30-SEP-17
Sponsor : University College Dublin (UCD)
Title : What is a real limb? Exploring boundaries between Art and Anatomy¿
Start Date / End Date : 15-MAY-15 / 30-JUN-16
Sponsor : University College Dublin (UCD)
Title : 3D-Printing of artificial muscle
Start Date / End Date : 01-APR-14 / 30-SEP-15
Sponsor : University College Dublin Foundation Ltd.
Title : A new model for studying eye development
Start Date / End Date : 01-JAN-13 / 31-DEC-13
Sponsor : University College Dublin (UCD)
Title : Anatomy start-up fund
Start Date / End Date : 01-OCT-12 / 30-SEP-15
Sponsor : Medtronic Inc.
Title : Reflex and behavioural studies of faecal continence and incontinence in an animal model and optimisation of frequency parameters of sacral neuromodulation
Start Date / End Date : 22-JUN-12 / 31-DEC-15
Sponsor : Science Foundation Ireland (SFI)
Title : The effect of sacral neuromodulation on inputs to the somatosensory cortex
Start Date / End Date : 01-SEP-11 / 30-SEP-15
Sponsor : Bowel Disease Research Foundation (BDRF)
Title : The effect of sacral neuromodulation on cortical processing of anal canal inputs in patients with faecal incontinence
Start Date / End Date : 01-OCT-11 / 01-OCT-12
Sponsor : Mater Misericordiae University Hospital
Title : The effect of pudendal nerve injury on sensory neurons in an animal model of neuropathic faecal incontinence
Start Date / End Date : 01-OCT-08 / 01-OCT-09
Sponsor : Royal College of Surgeons Ireland (RCSI)
Title : The effect of pudendal nerve injury on sensory neurons in animal models of neuropathic faecal incontinence
Start Date / End Date : 01-OCT-08 / 01-OCT-09
Sponsor : University College Dublin (UCD)
Title : Metabolic function in an animal model of sleep apnoea
Start Date / End Date : 26-MAY-08 / 01-DEC-09
Sponsor : Health Research Board (HRB)
Title : The action of sacral neuromodulation on an animal model of neuropathic faecal incontinence
Start Date / End Date : 01-SEP-07 / 31-AUG-10
Sponsor : University College Dublin (UCD)
Title : Role of nitric oxide in cardiac vagal ganglia
Start Date / End Date : 01-JUN-02 / 31-MAY-04
Sponsor : Health Research Board (HRB)
Title : Mechanism of laryngeal sensing of expired carbon dioxide
Start Date / End Date : 01-OCT-05 / 01-OCT-07
Sponsor : The Wellcome Trust (WT)
Title : Classification of cardiac vagal preganglionic neurones
Start Date / End Date : 01-MAR-00 / 28-FEB-03
Sponsor : Health Research Board (HRB)
Title : Central control of the crural diaphragm
Start Date / End Date : 01-OCT-99 / 30-SEP-02
Sponsor : Health Research Board (HRB)
Title : No Project title to migrate.
Start Date / End Date : 01-JUN-98 / 31-MAY-99
Sponsor : The Wellcome Trust (WT)
Title : No Project title to migrate.
Start Date / End Date : 01-OCT-96 / 30-SEP-99
Sponsor : British Council
Health Research Board (HRB)
Title : No Project title to migrate.
Start Date / End Date : 01-MAY-96 / 08-MAY-96
Sponsor : The Wellcome Trust (WT)
Title : The physiological role of paraganglia of the superior laryngeal nerve of the rat
Start Date / End Date : 01-JUN-06 / 01-JUN-08

Recent Postgraduates


PhD: Mark Pickering (2002)

MD: Ciaran Healy (2007)

PhD:  Lisa Fleming (2008)

MD: Colin Peirce (2010)

PhD: Karen Griffin (2011)

PhD: Maria Buffini (2012)

PhD: Edward O'Connor (2012) 

PhD: Deirdre Edge (2012)

MSc: Han Bing Chow (2012)

PhD: Catherine Redmond (2012)

MCh: Babatunde Soetan (2012)

PhD: Eric Lucking (2013)

MD: Liam Devane (2014)

PhD: Judith Ivers (2015) 

Current Postgraduate Students

Michelle Smith, Medicine (MD)   -   Thesis Supervisor
Eoin Mc Carthy Deering, Master of Science (MSc)   -   Thesis Supervisor
Thomas Campbell, Master of Science (MSc)   -   Thesis Supervisor
Luke Alvey, Doctor of Philosophy (PhD)   -   Thesis Co-Supervisor
Anna Lohikko, Undeclared   -   Thesis Supervisor
Claire Crowley, Master of Science (MSc)   -   Thesis Supervisor
Keira Turner, Doctor of Philosophy (PhD)   -   Thesis Supervisor

Collaborators

Internal Collaborators

Professors Ronan O'Connell (Surgery) 

Dr Sean Connolly (Clinical neurophysiology, St Vincent's hospital)

Dr Eoin O'Cearbhaill (School of Mechanical Engineering, UCD)
 
Dr Mark Pickering (Physiology,UCD)  

External Collaborators

Dr Charlie Knowles,
Academic Surgical Unit,
3rd Floor Alexandra Wing,
Royal London Hospital,
Whitechapel,
London E1 1BB.

Dr Sue Pyner
School of Biological and Biomedical Sciences
Durham University
Stockton Road
DH1 3LE
UK