Researchers at UCD

Kenneth Wolfe

Conway Institute of Biomolecular & Biomedical Research
Temporary office: Charles Institute, room F203

Tel: +353(0)1 716-6712



Conference Contributions

Lynch DB, Wolfe KH, Butler G; (2011) Comparative analysis of non-coding RNAs and novel transcripts in Candida albicans. [Poster Presentation], FEBS Advanced Course on Human Fungal Pathogens, La Colle sur Loup, Frnace , 08-MAY-11 - 13-MAY-11.


Year 1991 Institution: Trinity College Dublin
Qualification: PhD Subject:
Year 1987 Institution: Trinity College Dublin
Qualification: BA (Mod) Subject:



Peer Reviewed Journals

Monerawela C, James TC;Wolfe KH;Bond U (2015) 'Loss of lager specific genes and subtelomeric regions define two different Saccharomyces cerevisiae lineages for Saccharomyces pastorianus Group I and II strains'. FEMS Yeast Research, 15 (2). [DOI] [Details]
Wolfe KH (2015) 'Origin of the Yeast Whole-Genome Duplication'. PLoS Biology, 13 (8). [DOI] [Details]
Kobayashi N, Suzuki Y;Schoenfeld LW;M¿¿ller CA;Nieduszynski C;Wolfe KH;Tanaka TU (2015) 'Discovery of an unconventional centromere in budding yeast redefines evolution of point centromeres'. Current Biology, 25 (15):2026-2033. [DOI] [Details]
Wolfe KH, Armis¿¿n D;Proux-Wera E;¿¿h¿¿igeartaigh SS;Azam H;Gordon JL;Byrne KP (2015) 'Clade- and species-specific features of genome evolution in the Saccharomycetaceae'. FEMS Yeast Research, 15 (5). [DOI] [Details]
Maguire SL, Wang C, Holland LM, Brunel F, Neuveglise C, Nicaud JM, Zavrel M, White TC, Wolfe KH, Butler G. (2014) 'Zinc Finger Transcription Factors Displaced SREBP Proteins as the Major Sterol Regulators during Saccharomycotina Evolution'. PLoS Genetics, . [Details]
Pitoniak A, Chavel CA;Chow J;Smith J;Camara D;Karunanithi S;Li B;Wolfe KH;Cullen PJ (2014) 'Cdc42p-interacting protein Bem4p regulates the filamentous-growth mitogen-activated protein kinase pathway'. Molecular and Cellular Biology, 35 (2):417-436. [DOI] [Details]
Hanson SJ, Byrne KP;Wolfe KH (2014) 'Mating-type switching by chromosomal inversion in methylotrophic yeasts suggests an origin for the three-locus Saccharomyces cerevisiae system'. Proceedings of the National Academy of Sciences of the United States of America, 111 (45):1-8. [DOI] [Details]
¿¿h¿¿igeartaigh SS, Armis¿¿n D;Byrne KP;Wolfe KH (2014) 'SearchDOGS bacteria, software that provides automated identification of potentially missed genes in annotated bacterial genomes'. Journal of Bacteriology, 196 (11):2030-2042. [DOI] [Details]
Maguire SL, Ohéigeartaigh SS, Byrne KP, Schröder MS, O'Gaora P, Wolfe KH, Butler G (2013) 'Comparative Genome Analysis and Gene Finding in Candida Species Using CGOB'. Molecular Biology and Evolution, 30 (6):1281-1291. [DOI] Link to full text [Details]
Riccombeni1 A, Vidanes1 G, Proux-Wera E, Wolfe KH, Butler G (2012) 'Sequence and analysis of the genome of the pathogenic yeast Candida orthopsilosis'. PLoS ONE, 7 (e35750). [Details]
Khaldi N, Wolfe KH (2011) 'Evolutionary Origins of the Fumonisin Secondary Metabolite Gene Cluster in Fusarium verticillioides and Aspergillus niger'. International journal of evolutionary biology, 2011 . [DOI] [Details]
Lynch, DB,Logue, ME,Butler, G,Wolfe, KH; (2010) 'Chromosomal G+C Content Evolution in Yeasts: Systematic Interspecies Differences, and GC-Poor Troughs at Centromeres'. Genome Biology and Evolution, 2 :572-583. [DOI] [Details]
Khaldi N, Seifuddin FT, Turner G, Haft D, Nierman WC, Wolfe KH, Fedorova ND (2010) 'SMURF: Genomic mapping of fungal secondary metabolite clusters'. Fungal Genetics and Biology, 47 (9):736-741. [DOI] [Details]
Khaldi N, Wolfe KH (2008) 'Elusive origins of the extra genes in Aspergillus oryzae'. PLoS ONE, 3 (8). [DOI] [Details]
Khaldi N, Collemare J, Lebrun MH, Wolfe KH (2008) 'Evidence for horizontal transfer of a secondary metabolite gene cluster between fungi'. Genome Biology, 9 (1). [DOI] [Details]
Fedorova ND, Khaldi N, Joardar VS, Maiti R, Amedeo P, Anderson MJ, Crabtree J, Silva JC, Badger JH, Albarraq A, Angiuoli S, Bussey H, Bowyer P, Cotty PJ, Dyer PS, Egan A, Galens K, Fraser-Liggett CM, Haas BJ, Inman JM, Kent R, Lemieux S, Malavazi I, Orvis J, Roemer T, Ronning CM, Sundaram JP, Sutton G, Turner G, Venter JC, White OR, Whitty BR, Youngman P, Wolfe KH, Goldman GH, Wortman JR, Jiang B, Denning DW, Nierman WC (2008) 'Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus'. PLoS Genetics, 4 (4). [DOI] [Details]
Logue, ME; Wong, S; Wolfe, KH; Butler, G; ; (2005) 'A genome sequence survey shows that the pathogenic yeast Candida parapsilosis has a defective MTLa1 allele at its mating type locus'. Eukaryotic Cell, 4 (6):1009-1017. [Details]
Singer GA, Lloyd AT, Huminiecki LB, Wolfe KH. ; (2005) 'Clusters of co-expressed genes in mammalian genomes are conserved by natural selection'. Molecular Biology and Evolution, 22 :767-775. [Details]
Byrne KP, Wolfe KH (2005) 'The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species'. Genome Research, 15 (10):1456-1461. [DOI] [Details]
Butler, G,Kenny, C,Fagan, A,Kurischko, C,Gaillardin, C,Wolfe, KH; (2004) 'Evolution of the MAT locus and its Ho endonuclease in yeast species'. Proceedings of the National Academy of Sciences of the United States of America, 101 :1632-1637. [DOI] [Details]
Wong, S; Fares, MA; Zimmermann, W; Butler, G; Wolfe, KH; ; (2003) 'Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata'. Genome Biology, 4 (2). [Details]
Walsh, DW; Wolfe, KH; Butler, G; ; (2002) 'Genomic differences between Candida glabrata and Saccharomyces cerevisiae around the MRPL28 and GCN3 loci'. Yeast, 19 (11):991-994. [Details]
Wong, S,Butler, G,Wolfe, KH; (2002) 'Gene order evolution and paleopolyploidy in hemiascomycete yeasts'. Proceedings of the National Academy of Sciences of the United States of America, 99 :9272-9277. [DOI] [Details]
Hokamp K, Shields DC, Wolfe KH, Caffrey DC; (2002) 'Wrapping up BLAST and other applications for use on Unix clusters'. BIOINFORMATICS, (19):441-442. [Details]




Scannell, DR,Butler, G,Wolfe, KH (2007) Yeast genome evolution - the origin of the species. Reviews [DOI] [Details]


Research Interests

Research Projects

Sponsor : EC Framework (FP7)
Title : Prioritization of non-coding somatic mutations in cancer (NoCoSMiC)
Start Date / End Date : 01-MAY-14 / 30-APR-16
Sponsor : EC Framework (FP7)
Title : (YEASTCELL) Yeast Cell Factories: Training researchers to apply modern post-genomic methods in yeast biotechnology
Start Date / End Date : 01-SEP-13 / 31-AUG-17
Sponsor : Science Foundation Ireland (SFI)
Title : Sexual cycles, genomics and mating-type switching in non-conventional yeast species
Start Date / End Date : 01-SEP-14 / 01-SEP-19
Sponsor : EC Framework (FP7)
Title : (CHROMARRANGE) Programmed and unprogrammed genomic rearrangements during the evolution of yeast species
Start Date / End Date : 01-JUN-11 / 31-MAY-16