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Oliver Fitzgerald

Newman Clinical Research Professor/Full Professor

School of Medicine
St. Vincent's University Hospital
Elm Park
Dublin 4

Tel: 353 1 2213142
Email: oliver.fitzgerald@ucd.ie

Biography

Oliver FitzGerald is a consultant rheumatologist and Newman Clinical Research Professor at St Vincent's University Hospital and the Conway Institute, University College Dublin (UCD), Ireland. He qualified from UCD in 1978 and completed his postgraduate training both in Dublin and at the University of Cincinnati, Ohio, USA. 
Professor FitzGerald has published over 280 peer reviewed papers, many on the subject of inflammatory arthritis in particular psoriatic arthritis. His main research interests in psoriatic arthritis include clinical and therapeutic studies; the development of novel imaging techniques for measuring synovial or entheseal inflammation, including ultrasound and MRI; analysis of synovial and skin cellular and cytokine profiles; and, more recently, studies of gene and protein expression in diseased tissue. 

Professor FitzGerald has served on a number of editorial boards. He is a council member of the Group for Research and Assessment in Psoriasis and Psoriatic Arthritis (GRAPPA) and a member of the European Synovitis Study Group and of the Ankylosing Spondylitis Assessment (ASAS) Group. He is also working with the Outcome Measures in Rheumatoid Arthritis Clinical Trials (OMERACT) group to develop a longitudinal study of soluble biomarkers of joint damage. As chairman of Arthritis Ireland, he has played an important role in driving the appointment of Irelands first academic chair in Rheumatology.  Professor FitzGerald was HSE Programme Lead in Rheumatology between 2009-15.

Professional

 

Associations

Association: OMERACT, Function/Role: Member
Association: ASAS, Function/Role: Member
Association: GRAPPA, Function/Role: Executive
     

Conference Contributions

Fitzpatrick M, Fitzgerald O, Hurley DA. ; (2005) A Survey of the Quality of Life of Patients with Ankylosing Spondylitis. [National Refereed Conference Paper], Irish Rheumatology Health Professionals Society 8th Annual Autumn Scientific Meeting, St James¿s Hospital, Dublin , 14-OCT-05.
Fitzpatrick M, Fitzgerald O, Staines A, Hurley DA; (2006) Quality of life and exercise compliance in patients with Ankylosing Spondylitis: a cross-sectional survey. [International Refereed Conference], American College of Rheumatology Annual Scientific Meeting, Washington, DC, USA , 10-NOV-06 - 15-NOV-06.
Fitzpatrick M, Fitzgerald O, Staines A, Hurley DA; (2006) Exercise Activity in Patients with Ankylosing Spondylitis: A Cross-Sectional Survey. [National Refereed Conference Paper], Rehabilitation and Therapy Research Society Second Annual Scientific Meeting, UCD Health Sciences Centre, Dublin , 25-MAY-06 - 26-MAY-06.
               

Publications

Books

Ritchlin, C. and FitzGerald, O. (2007) Psoriatic and Reactive Arthritis: A Companion to Rheumatology. : Elsevier Inc. [Details]
Ritchlin, C.T. and FitzGerald, O. (2007) Pathogenesis of psoriatic arthritis. : Elsevier Inc. [DOI] [Details]

Book Chapters

Carr H, Ryan J, Joyce M, Fitzgerald O, Veale D, Gibney R, Brennan ; (2008) 'A Topological Approach to Quantitation of Rheumatoid Arthritis' In: Carr H, Ryan J, Joyce M, Fitzgerald O, Veale D, Gibney R, Brennan ; (eds). Visualization in Medicine and Life Sciences. Berlin: Lecture Notes in Computer Science, Springer-Verlag. [Details]
 

Peer Reviewed Journals

Minnock P, Ringn¿¿r A;Bresnihan B;Veale D;FitzGerald O;McKee G (2016) 'Perceptions of the Cause, Impact and Management of Persistent Fatigue in Patients with Rheumatoid Arthritis Following Tumour Necrosing Factor Inhibition Therapy'. Musculoskeletal care, . [DOI] [Details]
Haroon M, FitzGerald O (2016) 'Psoriatic arthritis: complexities, comorbidities and implications for the clinic'. Expert Review of Clinical Immunology, 12 (4):405-416. [DOI] [Details]
Coates LC, Kavanaugh A;Mease PJ;Soriano ER;Laura Acosta-Felquer M;Armstrong AW;Bautista-Molano W;Boehncke WH;Campbell W;Cauli A;Espinoza LR;FitzGerald O;Gladman DD;Gottlieb A;Helliwell PS;Husni ME;Love TJ;Lubrano E;McHugh N;Nash P;Ogdie A;Orbai AM;Parkinson A;O'Sullivan D;Rosen CF;Schwartzman S;Siegel EL;Toloza S;Tuong W;Ritchlin CT (2016) 'Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 Treatment Recommendations for Psoriatic Arthritis'. Arthritis & rheumatology (Hoboken, N.J.), 68 (5):1060-1071. [DOI] [Details]
Orbai AM, Mease PJ;de Wit M;Kalyoncu U;Campbell W;Tillett W;Eder L;Elmamoun M;FitzGerald O;Gladman DD;Goel N;Gossec L;Lindsay CA;Steinkoenig I;Helliwell PS;McHugh NJ;Strand V;Ogdie A (2016) 'Report of the GRAPPA-OMERACT Psoriatic Arthritis Working Group from the GRAPPA 2015 Annual Meeting'. The Journal of rheumatology, 43 (5):965-969. [DOI] [Details]
Mease PJ, Helliwell PS;Boehncke WH;Coates LC;FitzGerald O;Gladman DD;Deodhar AA;Callis Duffin K (2016) 'GRAPPA 2015 Research and Education Project Reports'. The Journal of rheumatology, 43 (5):979-985. [DOI] [Details]
Szentpetery A, Heffernan E;Haroon M;Kilbane M;Gallagher P;McKenna MJ;FitzGerald O (2016) 'Striking difference of periarticular bone density change in early psoriatic arthritis and rheumatoid arthritis following anti-rheumatic treatment as measured by digital X-ray radiogrammetry'. Rheumatology (Oxford, England), . [DOI] [Details]
Sepriano A, Landew¿¿ R;van der Heijde D;Sieper J;Akkoc N;Brandt J;Braun J;Collantes-Estevez E;Dougados M;Fitzgerald O;Huang F;Gu J;Kirazli Y;Maksymowych WP;Marzo-Ortega H;Olivieri I;Ozgocmen S;Roussou E;Scarpato S;S¿¿rensen IJ;Valle-O¿¿ate R;Van den Bosch F;van der Horst-Bruinsma I;Weber U;Wei J;Rudwaleit M; (2016) 'Predictive validity of the ASAS classification criteria for axial and peripheral spondyloarthritis after follow-up in the ASAS cohort: a final analysis'. Annals of the Rheumatic Diseases, . [DOI] [Details]
Bowes J, Budu-Aggrey A;Huffmeier U;Uebe S;Steel K;Hebert HL;Wallace C;Massey J;Bruce IN;Bluett J;Feletar M;Morgan AW;Marzo-Ortega H;Donohoe G;Morris DW;Helliwell P;Ryan AW;Kane D;Warren RB;Korendowych E;Alenius GM;Giardina E;Packham J;McManus R;FitzGerald O;McHugh N;Brown MA;Ho P;Behrens F;Burkhardt H;Reis A;Barton A (2015) 'Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis'. Nature Communications, 6 . [DOI] [Details]
Ademowo OS, Hernandez B;Collins E;Rooney C;Fearon U;van Kuijk AW;Tak PP;Gerlag DM;FitzGerald O;Pennington SR (2015) 'Discovery and confirmation of a protein biomarker panel with potential to predict response to biological therapy in psoriatic arthritis'. Annals of the Rheumatic Diseases, 75 (1):234-241. [DOI] [Details]
Harty L, Clare J;Finnerty D;van der Kamp S;Kennedy F;Callanan I;McKenna MJ;FitzGerald O (2015) 'Guideline Promotion Increases Prescription of Bone Protection with Steroids in Hospitalised Patients'. Irish Medical Journal, 108 (7):216-217. [Details]
Mease P, Deodhar A;Fleischmann R;Wollenhaupt J;Gladman D;Leszczy¿¿ski P;Vitek P;Turkiewicz A;Khraishi M;FitzGerald O;Landew¿¿ R;de Longueville M;Hoepken B;Peterson L;van der Heijde D (2015) 'Effect of certolizumab pegol over 96¿¿¿weeks in patients with psoriatic arthritis with and without prior antitumour necrosis factor exposure'. RMD open, 1 (1). [DOI] [Details]
Gossec L, Smolen JS;Ramiro S;de Wit M;Cutolo M;Dougados M;Emery P;Landew¿¿ R;Oliver S;Aletaha D;Betteridge N;Braun J;Burmester G;Ca¿¿ete JD;Damjanov N;FitzGerald O;Haglund E;Helliwell P;Kvien TK;Lories R;Luger T;Maccarone M;Marzo-Ortega H;McGonagle D;McInnes IB;Olivieri I;Pavelka K;Schett G;Sieper J;van den Bosch F;Veale DJ;Wollenhaupt J;Zink A;van der Heijde D (2015) 'European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update'. Annals of the Rheumatic Diseases, . [DOI] [Details]
Haroon M, O'Rourke M;Ramasamy P;Murphy CC;FitzGerald O (2015) 'A novel evidence-based detection of undiagnosed spondyloarthritis in patients presenting with acute anterior uveitis: the DUET (Dublin Uveitis Evaluation Tool)'. Annals of the Rheumatic Diseases, 74 (11):1990-1995. [DOI] [Details]
Acosta Felquer ML, FitzGerald O (2015) 'Peripheral joint involvement in psoriatic arthritis patients'. Clinical and Experimental Rheumatology, 33 (5 Suppl 93):26-30. [Details]
Minnock P, Veale DJ;Bresnihan B;FitzGerald O;McKee G (2015) 'Factors that influence fatigue status in patients with severe rheumatoid arthritis (RA) and good disease outcome following 6¿¿months of TNF inhibitor therapy: a comparative analysis'. Journal of Clinical Rheumatology, 34 (11):1857-1865. [DOI] [Details]
Bowes J, Loehr S;Budu-Aggrey A;Uebe S;Bruce IN;Feletar M;Marzo-Ortega H;Helliwell P;Ryan AW;Kane D;Korendowych E;Alenius GM;Giardina E;Packham J;McManus R;FitzGerald O;Brown MA;Behrens F;Burkhardt H;McHugh N;Huffmeier U;Ho P;Reis A;Barton A (2015) 'PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus'. Annals of the Rheumatic Diseases, 74 (10):1882-1885. [DOI] [Details]
McArdle A, Butt AQ;Szentpetery A;de Jager W;de Roock S;FitzGerald O;Pennington SR (2015) 'Developing Clinically Relevant Biomarkers in Inflammatory Arthritis: A Multi-Platform Approach for Serum Candidate Protein Discovery'. Proteomics - Clinical Applications, . [DOI] [Details]
Collins ES, Butt AQ;Gibson DS;Dunn MJ;Fearon U;van Kuijk AW;Gerlag DM;Pontifex E;Veale DJ;Tak PP;FitzGerald O;Pennington SR (2015) 'A clinically based protein discovery strategy to identify potential biomarkers of response to anti-TNF-¿¿ treatment of psoriatic arthritis'. Proteomics - Clinical Applications, . [DOI] [Details]
Haroon M, Gallagher P;FitzGerald O (2015) 'Diagnostic delay of more than 6¿¿¿months contributes to poor radiographic and functional outcome in psoriatic arthritis'. Annals of the Rheumatic Diseases, 74 (6):1045-1050. [DOI] [Details]
Mc Ardle A, Flatley B;Pennington SR;FitzGerald O (2015) 'Early biomarkers of joint damage in rheumatoid and psoriatic arthritis'. Arthritis Research and Therapy, 17 . [DOI] [Details]
Humby F, Kelly S;Bugatti S;Manzo A;Filer A;Mahto A;Fonseca JE;Lauwerys B;D'Agostino MA;Naredo E;Lories R;Montecucco C;Tak PP;Fitzgerald O;Smith MD;Veale DJ;Choy EH;Strand V;Pitzalis C (2015) 'Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter-determining Validation Requirements'. Rheumatology, . [DOI] [Details]
FitzGerald O, Haroon M;Giles JT;Winchester R (2015) 'Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype'. Arthritis Research and Therapy, 17 . [DOI] [Details]
Butt AQ, McArdle A;Gibson DS;FitzGerald O;Pennington SR (2015) 'Psoriatic arthritis under a proteomic spotlight: application of novel technologies to advance diagnosis and management'. Current Rheumatology Reports, 17 (5). [DOI] [Details]
Tillett W, Eder L;Goel N;De Wit M;Gladman DD;FitzGerald O;Campbell W;Helliwell PS;Gossec L;Orbai AM;Ogdie A;Strand V;McHugh NJ;Mease PJ (2015) 'Enhanced Patient Involvement and the Need to Revise the Core Set - Report from the Psoriatic Arthritis Working Group at OMERACT 2014'. Rheumatology, 42 (11):2198-2203. [DOI] [Details]
Harty L, O'Toole G;FitzGerald O (2015) 'Profound reduction in hospital admissions and musculoskeletal surgical procedures for rheumatoid arthritis with concurrent changes in clinical practice (1995-2010)'. Rheumatology [formerly the British journal of rheumatology], 54 (4):666-671. [DOI] [Details]
Ademowo, O.S. and Hernandez, B. and Collins, E. and Rooney, C. and Fearon, U. and van Kuijk, A.W. and Tak, P.-P. and Gerlag, D.M. and FitzGerald, O. and Pennington, S.R. (2014) 'Discovery and confirmation of a protein biomarker panel with potential to predict response to biological therapy in psoriatic arthritis'. Annals of the Rheumatic Diseases, . Available Online [DOI] [Details]
Boehncke, W.H. and Kirby, B. and Fitzgerald, O. and Van De Kerkhof, P.C.M. (2014) 'New developments in our understanding of psoriatic arthritis and their impact on the diagnosis and clinical management of the disease'. Journal of the European Academy of Dermatology and Venereology, 28 (3):264-270. Available Online [DOI] [Details]
Emery P, Hammoudeh M;FitzGerald O;Combe B;Martin-Mola E;Buch MH;Krogulec M;Williams T;Gaylord S;Pedersen R;Bukowski J;Vlahos B (2014) 'Sustained remission with etanercept tapering in early rheumatoid arthritis'. New England Journal of Medicine, 371 (19):1781-1792. [DOI] [Details]
Minnock P, McKee G;Bresnihan B;FitzGerald O;Veale DJ (2014) 'How much is fatigue explained by standard clinical characteristics of disease activity in patients with inflammatory arthritis? A longitudinal study'. Arthritis Care and Research, 66 (11):1597-1603. [DOI] [Details]
Acosta Felquer ML, Coates LC;Soriano ER;Ranza R;Espinoza LR;Helliwell PS;FitzGerald O;McHugh N;Roussou E;Mease PJ (2014) 'Drug therapies for peripheral joint disease in psoriatic arthritis: a systematic review'. Rheumatology, 41 (11):2277-2285. [DOI] [Details]
Haroon M, Winchester R;Giles JT;Heffernan E;FitzGerald O (2014) 'Certain class I HLA alleles and haplotypes implicated in susceptibility play a role in determining specific features of the psoriatic arthritis phenotype'. Annals of the Rheumatic Diseases, . [DOI] [Details]
Fitzgerald, O. and Winchester, R. (2014) 'Editorial: Emerging evidence for critical involvement of the interleukin-17 pathway in both psoriasis and psoriatic arthritis'. Arthritis and Rheumatology, 66 (5):1077-1080. Available Online [DOI] [Details]
Fitzgerald, O. (2014) 'Spondyloarthropathies: Apremilast: Welcome advance in treatment of psoriatic arthritis'. Nature Reviews Rheumatology, 10 (7):385-386. Available Online [DOI] [Details]
Smolen, J.S. and Braun, J. and Dougados, M. and Emery, P. and FitzGerald, O. and Helliwell, P. and Kavanaugh, A. and Kvien, T.K. and Landewé, R. and Luger, T. and Mease, P. and Olivieri, I. and Reveille, J. and Ritchlin, C. and Rudwaleit, M. and Schoels, M. and Sieper, J. and De Wit, M. and Baraliakos, X. and Betteridge, N. and Burgos-Vargas, R. and Collantes-Estevez, E. and Deodhar, A. and Elewaut, D. and Gossec, L. and Jongkees, M. and Maccarone, M. and Redlich, K. and Van Den Bosch, F. and Cheng-Chung Wei, J. and Winthrop, K. and Van Der Heijde, D. (2014) 'Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: Recommendations of an international task force'. Annals of the Rheumatic Diseases, 73 (1):6-16. Available Online [DOI] [Details]
FitzGerald, O. and Mease, P.J. and Helliwell, P.S. and Chandran, V. (2014) 'GRAPPA 2013 annual meeting, rheumatology updates: Psoriatic arthritis (PsA) biomarker project, arthritis mutilans, PsA-peripheral spondyloarthritis epidemiology project'. Journal of Rheumatology, 41 (6):1244-1248. Available Online [DOI] [Details]
Tillett, W. and Adebajo, A. and Brooke, M. and Campbell, W. and Coates, L.C. and FitzGerald, O. and Gossec, L. and Helliwell, P. and Hewlett, S. and James, J. and Minnock, P. and Reast, A. and O'Sullivan, D. and De Wit, M. and McHugh, N. (2014) 'Patient involvement in outcome measures for Psoriatic arthritis'. Current Rheumatology Reports, 16 (5). Available Online [DOI] [Details]
Schoels, M.M. and Braun, J. and Dougados, M. and Emery, P. and Fitzgerald, O. and Kavanaugh, A. and Kvien, T.K. and Landewé, R. and Luger, T. and Mease, P. and Olivieri, I. and Reveille, J. and Ritchlin, C. and Rudwaleit, M. and Sieper, J. and Smolen, J.S. and De Wit, M. and Van Der Heijde, D. (2014) 'Treating axial and peripheral spondyloarthritis, including psoriatic arthritis, to target: Results of a systematic literature search to support an international treat-to-target recommendation in spondyloarthritis'. Annals of the Rheumatic Diseases, 73 (1):238-242. Available Online [DOI] [Details]
De Wit, M. and Campbell, W. and FitzGerald, O. and Gladman, D.D. and Helliwell, P.S. and James, J. and Lindsay, C. and MacDonald, R. and McHugh, N.J. and Mease, P.J. and Orbai, A.-M. and Palominos, P. and Parkinson, A. and Tillett, W. and Goel, N. (2014) 'Patient participation in psoriasis and psoriatic arthritis outcome research: A report from the GRAPPA 2013 annual meeting'. Journal of Rheumatology, 41 (6):1206-1211. Available Online [DOI] [Details]
Coates, L.C. and Walsh, J. and Haroon, M. and Fitzgerald, O. and Aslam, T. and Al Balushi, F. and Burden, A.D. and Burden-Teh, E. and Caperon, A.R. and Cerio, R. and Chattopadhyay, C. and Chinoy, H. and Goodfield, M.J.D. and Kay, L. and Kelly, S. and Kirkham, B.W. and Lovell, C.R. and Marzo-Ortega, H. and McHugh, N. and Murphy, R. and Reynolds, N.J. and Smith, C.H. and Stewart, E.J.C. and Warren, R.B. and Waxman, R. and Wilson, H.E. and Helliwell, P.S. (2014) 'Development and testing of new candidate psoriatic arthritis screening questionnaires combining optimal questions from existing tools'. Arthritis Care and Research, 66 (9):1410-1416. Available Online [DOI] [Details]
Helliwell, P.S. and FitzGerald, O. and Fransen, J. (2014) 'Composite disease activity and responder indices for psoriatic arthritis: A report from the GRAPPA 2013 meeting on development of cutoffs for both disease activity states and response'. Journal of Rheumatology, 41 (6):1212-1217. Available Online [DOI] [Details]
Coates, L.C. and FitzGerald, O. and Mease, P.J. and Gladman, D.D. and Strand, V. and Goel, N. and Campbell, I. and Krueger, G. and McHugh, N.J. and Helliwell, P.S. (2014) 'Development of a disease activity and responder index for psoriatic arthritis - Report of the psoriatic arthritis module at OMERACT 11'. Journal of Rheumatology, 41 (4):782-791. Available Online [DOI] [Details]
Haroon, M. and Gallagher, P. and Heffernan, E. and FitzGerald, O. (2014) 'High prevalence of metabolic syndrome and of insulin resistance in psoriatic arthritis is associated with the severity of underlying disease'. Journal of Rheumatology, 41 (7):1357-1365. Available Online [DOI] [Details]
Haroon, M. and Gallagher, P. and FitzGerald, O. (2014) 'Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis'. Annals of the Rheumatic Diseases, . Available Online [DOI] [Details]
Haroon, M. and O'Rourke, M. and Ramasamy, P. and Murphy, C.C. and FitzGerald, O. (2014) 'A novel evidence-based detection of undiagnosed spondyloarthritis in patients presenting with acute anterior uveitis: The DUET (Dublin Uveitis Evaluation Tool)'. Annals of the Rheumatic Diseases, . Available Online [DOI] [Details]
Mongey AB, Doran JP, Kleinerova J, Fitzgerald O, McDonnell TJ. (2013) 'Late onset tuberculosis infection in patients receiving anti-TNFα therapy'. Qjm-Monthly Journal of the Association of Physicians, . [Details]
Helliwell PS, FitzGerald O;Fransen J;Gladman DD;Kreuger GG;Callis-Duffin K;McHugh N;Mease PJ;Strand V;Waxman R;Azevedo VF;Beltran Ostos A;Carneiro S;Cauli A;Espinoza LR;Flynn JA;Hassan N;Healy P;Kerzberg EM;Lee YJ;Lubrano E;Marchesoni A;Marzo-Ortega H;Porru G;Moreta EG;Nash P;Raffayova H;Ranza R;Raychaudhuri SP;Roussou E;Scarpa R;Song YW;Soriano ER;Tak PP;Ujfalussy I;de Vlam K;Walsh JA (2013) 'The development of candidate composite disease activity and responder indices for psoriatic arthritis (GRACE project)'. Annals of the Rheumatic Diseases, 72 (6):986-991. [DOI] [Details]
Balogh, E. and Dias, J.M. and Orr, C. and Mullan, R. and Harty, L. and FitzGerald, O. and Gallagher, P. and Molloy, M. and O'Flynn, E. and Kelly, A. and Minnock, P. and O'Neill, M. and Moore, L. and Murray, M. and Fearon, U. and Veale, D.J. (2013) 'Comparison of remission criteria in a tumour necrosis factor inhibitor treated rheumatoid arthritis longitudinal cohort: Patient global health is a confounder'. Arthritis Research and Therapy, 15 (6). Available Online [DOI] [Details]
Szentpetery, A. and McKenna, M.J. and Murray, B.F. and Ng, C.T. and Brady, J.J. and Morrin, M. and Radovits, B. and Veale, D.J. and FitzGerald, O. (2013) 'Periarticular bone gain at proximal interphalangeal joints and changes in bone turnover markers in response to tumor necrosis factor inhibitors in rheumatoid and psoriatic arthritis'. Journal of Rheumatology, 40 (5):653-662. Available Online [DOI] [Details]
Collins, E.S. and Galligan, M.C. and Saldova, R. and Adamczyk, B. and Abrahams, J.L. and Campbell, M.P. and Ng, C.-T. and Veale, D.J. and Murphy, T.B. and Rudd, P.M. and FitzGerald, O. (2013) 'Glycosylation status of serum in inflammatory arthritis in response to anti-TNF treatment'. Rheumatology (United Kingdom), 52 (9):1572-1582. Available Online [DOI] [Details]
McMorrow, J.P. and Crean, D. and Gogarty, M. and Smyth, A. and Connolly, M. and Cummins, E. and Veale, D. and Fearon, U. and Tak, P.P. and Fitzgerald, O. and Murphy, E.P. (2013) 'Tumor necrosis factor inhibition modulates thrombospondin-1 expression in human inflammatory joint disease through altered nr4a2 activity'. American Journal of Pathology, 183 (4):1243-1257. Available Online [DOI] [Details]
Balogh, E. and Dias, J.M. and Orr, C. and Mullan, R. and Harty, L. and FitzGerald, O. and Gallagher, P. and Molloy, M. and O'Flynn, E. and Kelly, A. and Minnock, P. and O'Neill, M. and Moore, L. and Murray, M. and Fearon, U. and Veale, D.J. (2013) 'Comparison of remission criteria in a tumour necrosis factor inhibitor treated rheumatoid arthritis longitudinal cohort: Patient global health is a confounder'. Arthritis Research and Therapy, 15 (6). Available Online [DOI] [Details]
Haroon, M. and Kirby, B. and FitzGerald, O. (2013) 'High prevalence of psoriatic arthritis in patients with severe psoriasis with suboptimal performance of screening questionnaires'. Annals of the Rheumatic Diseases, 72 (5):736-740. Available Online [DOI] [Details]
Mongey AB, Doran JP;Kleinerova J;Fitzgerald O;McDonnell TJ (2013) 'Late onset tuberculosis infection in patients receiving anti-TNF¿¿ therapy'. Qjm-An International Journal Of Medicine, 107 (1):69-71. [DOI] [Details]
Apel, M,Uebe, S,Bowes, J,Giardina, E,Korendowych, E,Juneblad, K,Pasutto, F,Ekici, AB,McManus, R,Ho, P,Bruce, IN,Ryan, AW,Behrens, F,Bohm, B,Traupe, H,Lohmann, J,Gieger, C,Wichmann, HE,Padyukov, L,FitzGerald, O,Alenius, GM,McHugh, NJ,Novelli, G,Burkhardt, H,Barton, A,Reis, A,Huffmeier, U (2013) 'Variants in RUNX3 Contribute to Susceptibility to Psoriatic Arthritis, Exhibiting Further Common Ground With Ankylosing Spondylitis'. Arthritis and Rheumatism, 65 :1224-1231. [DOI] [Details]
French HP, Cusack T, Brennan A, White B, Gilsenan C, Fitzpatrick M, O'Connell P, Kane D, Fitzgerald O, McCarthy GM (2013) 'Exercise and Manual therapy Arthritis Research trial (EMPART) for osteoarthritis of the hip: A Multicentre Randomised Controlled trial'. Archives of Physical Medicine and Rehabilitation, . [Details]
Putrik P, Ramiro S, Kvien TK, Sokka T, Pavlova M, Uhlig T, Boonen A (2013) 'Working Group 'Equity in access to treatment of rheumatoid arthritis in Europe'. Inequities in access to biologic and synthetic DMARDs across 46 European countries'. Annals of Rheumatic Diseases, . [Details]
Coates LC, FitzGerald O, Gladman DD, McHugh N, Mease P, Strand V, Helliwell PS. (2013) 'Reduced joint counts misclassify patients with oligoarticular psoriatic arthritis and miss significant numbers of patients with active disease'. Arthritis Rheumatology, . [Details]
Schoels MM, Braun J, Dougados M, Emery P, Fitzgerald O, Kavanaugh A, Kvien TK, Landewé R, Luger T, Mease P, Olivieri I, Reveille J, Ritchlin C, Rudwaleit M, Sieper J, Smolen JS, Wit MD, van der Heijde D (2013) 'Treating axial and peripheral spondyloarthritis, including psoriatic arthritis, to target: results of a systematic literature search to support an international treat-to-target recommendation in spondyloarthritis'. Annals of Rheumatic Diseases, . [Details]
Smolen JS, Braun J, Dougados M, Emery P, Fitzgerald O, Helliwell P, Kavanaugh A, Kvien TK, Landewé R, Luger T, Mease P, Olivieri I, Reveille J, Ritchlin C, Rudwaleit M, Schoels M, Sieper J, Wit MD, Baraliakos X, Betteridge N, Burgos-Vargas R, Collantes-Estevez E, Deodhar A, Elewaut D, Gossec L, Jongkees M, Maccarone M, Redlich K, van den Bosch F, Wei JC, Winthrop K, van der Heijde D. (2013) 'Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force'. Annals of Rheumatic Diseases, . [Details]
Cobb JE, Plant D, Flynn E, Tadjeddine M, Dieudé P, Cornélis F, Ärlestig L, Dahlqvist SR, Goulielmos G, Boumpas DT, Sidiropoulos P, Krintel SB, Ørnbjerg LM, Hetland ML, Klareskog L, Haeupl T, Filer A, Buckley CD, Raza K, Witte T, Schmidt RE, FitzGerald O, Veale D, Eyre S, Worthington J. (2013) 'Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans'. PLoS ONE, . [Details]
Helliwell PS, Mease PJ, FitzGerald O, Taylor WJ, van der Heijde D. (2013) 'Peripheral spondyloarthritis and psoriatic arthritis; overlaps and distinctions: a report from the GRAPPA 2012 annual meeting'. Journal of Rheumatology, . [Details]
FitzGerald O, Mease PJ (2013) 'Biomarkers: project update from the GRAPPA 2012 annual meeting'. Journal of Rheumatology, . [Details]
Boehncke WH, Kirby B, Fitzgerald O, van de Kerkhof PC (2013) 'New developments in our understanding of psoriatic arthritis and their impact on the diagnosis and clinical management of the disease'. J Am Acad Dermatol, . [Details]
Haroon, M,Fitzgerald, O (2012) 'Pathogenetic Overview of Psoriatic Disease'. Journal of Rheumatology, 39 :7-10. [DOI] [Details]
Connolly, M. and Mullan, R.H. and McCormick, J. and Matthews, C. and Sullivan, O. and Kennedy, A. and FitzGerald, O. and Poole, A.R. and Bresnihan, B. and Veale, D.J. and Fearon, U. (2012) 'Acute-phase serum amyloid A regulates tumor necrosis factor α and matrix turnover and predicts disease progression in patients with inflammatory arthritis before and after biologic therapy'. Arthritis and Rheumatism, 64 (4):1035-1045. Available Online [DOI] [Details]
Winchester, R. and Minevich, G. and Steshenko, V. and Kirby, B. and Kane, D. and Greenberg, D.A. and FitzGerald, O. (2012) 'HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype'. Arthritis and Rheumatism, 64 (4):1134-1144. Available Online [DOI] [Details]
Helliwell PS, FitzGerald O, Mease PJ (2012) 'Development of composite measures for psoriatic arthritis: a report from the GRAPPA 2010 annual meeting'. Journal of Rheumatology, . [Details]
FitzGerald O, Chandran V (2012) 'Update on biomarkers in psoriatic arthritis: a report from the GRAPPA 2010 annual meeting'. Journal of Rheumatology, . [Details]
Gladman DD, Ritchlin CT, FitzGerald O (2012) 'The path forward to biomarker discovery in psoriatic disease: a report from the GRAPPA 2010 annual meeting'. Journal of Rheumatology, . [Details]
Bowes J, Ho P, Flynn E, Ali F, Marzo-Ortega H, Coates LC, Warren RB, McManus R, Ryan AW, Kane D, Korendowych E, McHugh N, FitzGerald O, Packham J, Morgan AW, Bruce IN, Barton A (2012) 'Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort'. Annals of Rheumatic Diseases, . [Details]
Haroon M, Kirby B, FitzGerald O (2012) 'High prevalence of psoriatic arthritis in patients with severe psoriasis with suboptimal performance of screening questionnaires'. Annals of Rheumatic Diseases, . [Details]
Winchester, R,Minevich, G,Steshenko, V,Kirby, B,Kane, D,Greenberg, DA,FitzGerald, O (2012) 'HLA Associations Reveal Genetic Heterogeneity in Psoriatic Arthritis and in the Psoriasis Phenotype'. Arthritis and Rheumatism, 64 :1134-1144. [DOI] [Details]
FitzGerald, O,Helliwell, P,Mease, P,Mumtaz, A,Coates, L,Pedersen, R,Nab, H,Molta, C (2012) 'Application of composite disease activity scores in psoriatic arthritis to the PRESTA data set'. Annals of the Rheumatic Diseases, 71 :358-362. [DOI] [Details]
FitzGerald O. (2012) 'Diagnosis: Screening for arthritis in patients with psoriasis'. Journal of Rheumatology, . [Details]
Doyle MS, Collins ES, Fitzgerald OM, Pennington SR. (2012) 'New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis'. Arthritis Research & Therapy, . [Details]
Helliwell PS, Fitzgerald O, Mease PJ, Gladman DD. (2012) 'GRAPPA Responder Index Project (GRACE): a report from the GRAPPA 2011 annual meeting'. Journal of Rheumatology, . [Details]
Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y, Tejasvi T, Gudjonsson JE, Kang HM, Allen MH, McManus R, Novelli G, Samuelsson L, Schalkwijk J, Ståhle M, Burden AD, Smith CH, Cork MJ, Estivill X, Bowcock AM, Krueger GG, Weger W, Worthington J, Tazi-Ahnini R, Nestle FO, Hayday A, Hoffmann P, Winkelmann J, Wijmenga C, Langford C, Edkins S, Andrews R, Blackburn H, Strange A, Band G, Pearson RD, Vukcevic D, Spencer CC, Deloukas P, Mrowietz U, Schreiber S, Weidinger S, Koks S, Kingo K, Esko T, Metspalu A, Lim HW, Voorhees JJ, Weichenthal M, Wichmann HE, Chandran V, Rosen CF, Rahman P, Gladman DD, Griffiths CE, Reis A, Kere J (2012) 'Collaborative Association Study of Psoriasis (CASP); Genetic Analysis of Psoriasis Consortium; Psoriasis Association Genetics Extension; Wellcome Trust Case Control Consortium 2, Nair RP, Franke A, Barker JN, Abecasis GR, Elder JT, Trembath RC. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity'. Nature Genetics, . [Details]
Fitzgerald, O,Ritchlin, CT,Mease, PJ (2012) 'Biomarkers of Radiographic Progression in Psoriatic Arthritis: A Report from the GRAPPA 2011 Annual Meeting'. Journal of Rheumatology, 39 :2189-2192. [DOI] [Details]
French, HP,Fitzpatrick, M,FitzGerald, O (2011) 'Responsiveness of physical function outcomes following physiotherapy intervention for osteoarthritis of the knee: an outcome comparison study'. Physiotherapy, 97 :302-308. [DOI] [Details]
Hegarty C;Jackson M;Keane D;Fitzgerald O;Bresnihan B;Veale D;Dodd JD, Nicholson PJ (2011) 'Pulmonary fibrosis in systemic sclerosis: association with myocardial fibrosis'. Journal of Thoracic Imaging, 27 (1):44-50. [DOI] [Details]
Collins NE, Fitzgerald O, Murphy CC; (2011) 'Clinical Image: Keratitis in reactive arthritis'. Arthritis Rheumatology, . [Details]
Bowes J, Ho P, Flynn E, Salah S, McHugh N, Fitzgerald O, Packham J, Morgan AW,; (2011) 'Investigation of IL1, VEGF, PPARG and MEFV genes in psoriatic arthritis susceptibility'. Annals of Rheumatic Diseases, . [Details]
Ash Z, Gaujoux-Viala C, Gossec L, Hensor EM, Fitzgerald O, Winthrop K, van der; (2011) 'A systematic literature review of drug therapies for the treatment of psoriatic arthritis: current evidence and meta-analysis informing the EULAR recommendations for the management of psoriatic arthritis'. Annals of Rheumatic Diseases, . [Details]
Helliwell PS, Fitzgerald O, Strand CV, Mease PJ; (2011) 'Composite Measures in Psoriatic Arthritis: a report from the GRAPPA 2009 annual meeting'. Journal of Rheumatology, . [Details]
Reid A, Brady A, Blake C, Mongey AB, Veale DJ, FitzGerald O, Cusack T; (2011) 'Randomised controlled trial examining the effect of exercise in people with rheumatoid arthritis taking anti-TNFα therapy medication'. BMC Musculoskeletal Disorders, . [Details]
Winchester R, Minevich G, Steshenko V, Kirby B, Kane D, Greenberg DA, Fitzgerald O; (2011) 'HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype'. Arthritis Rheumatology, . [Details]
Schmitz S, Adams R, Walsh CD, Barry M, Fitzgerald O; (2011) 'A mixed treatment comparison of the efficacy of anti-TNF agents in rheumatoid arthritis for methotrexate non-responders demonstrates differences between treatments: a Bayesian approach'. Annals of Rheumatic Diseases, . [Details]
Gossec L, Smolen JS, Gaujoux-Viala C, Ash Z, Marzo-Ortega H, van der Heijde D, Fitzgerald O, Aletaha D, Balint P, Boumpas D, Braun J, Breedveld FC, Burmester G, Cañete JD, de Wit M, Dagfinrud H, de Vlam K, Dougados M, Helliwell P, Kavanaugh A, Kvien TK, Landewé R, Luger T, Maccarone M, McGonagle D, McHugh N, McInnes IB, Ritchlin C, Sieper J, Tak PP, Valesini G, Vencovsky J, Winthrop KL, Zink A, Emery P; (2011) 'European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies'. Annals of Rheumatic Diseases, . [Details]
Bowes, J,Orozco, G,Flynn, E,Ho, P,Brier, R,Marzo-Ortega, H,Coates, L,McManus, R,Ryan, AW,Kane, D,Korendowych, E,McHugh, N,FitzGerald, O,Packham, J,Morgan, AW,Bruce, IN,Barton, A; (2011) 'Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis'. Annals of the rheumatic diseases, 70 :1641-1644. [DOI] [Details]
Coates, LC,Mumtaz, A,Helliwell, PS,Mease, PJ,Callis-Duffin, K,Krueger, GG,McHugh, NJ,Strand, V,Gladman, DD,Fitzgerald, O; (2011) 'Development of a Disease Severity and Responder Index for Psoriatic Arthritis (PsA) - Report of the OMERACT 10 PsA Special Interest Group'. Journal of Rheumatology, 38 :1496-1501. [DOI] [Details]
Bowes, J,Eyre, S,Flynn, E,Ho, P,Salah, S,Warren, RB,Marzo-Ortega, H,Coates, L,McManus, R,Ryan, AW,Kane, D,Korendowych, E,McHugh, N,FitzGerald, O,Packham, J,Morgan, AW,Griffiths, CEM,Bruce, IN,Worthington, J,Barton, A; (2011) 'Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris'. Annals of the Rheumatic Diseases, 70 :1016-1019. [DOI] [Details]
Prinz, JC,FitzGerald, O,Boggs, RL,Foehl, J,Robertson, D,Pedersen, R,Molta, CT,Freundlich, B; (2011) 'Combination of skin, joint and quality of life outcomes with etanercept in psoriasis and psoriatic arthritis in the PRESTA trial'. Europe, 25 :559-564. [DOI] [Details]
Mumtaz, A,Gallagher, P,Kirby, B,Waxman, R,Coates, LC,Veale, JD,Helliwell, P,FitzGerald, O; (2011) 'Development of a preliminary composite disease activity index in psoriatic arthritis'. Annals of the Rheumatic Diseases, 70 :272-277. [DOI] [Details]
Adams R, Craig BM, Walsh CD, Veale DJ, Bresnihan B, FitzGerald O, Barry M; (2011) 'The impact of a revised EQ-5D population scoring on preference-based utility scores in an inflammatory arthritis cohort'. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 14 (6):921-927. [DOI] [Details]
Pontifex EK, Gerlag DM, Gogarty M, Vinkenoog M, Gibbs A, Burgman I, Fearon U, Bresnihan B, Tak PP, Gibney RG, Veale DJ, Fitzgerald O; (2011) 'Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with change in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy - a single centre, open-label study'. Arthritis Research and Therapy, 13 (1). [DOI] [Details]
Walsh CE, Ryan EJ, O'Farrelly C, Golden-Mason L, FitzGerald O, Veale DJ, Bresnihan B, Fearon U (2011) 'Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease'. PLoS ONE, . [Details]
FitzGerald O, Helliwell P, Mease P, Mumtaz A, Coates L, Pedersen R, Nab H, Molta C (2011) 'Application of composite disease activity scores in psoriatic arthritis to the PRESTA data set'. Annals of Rheumatic Diseases, . [Details]
Haroon M, Fitzgerald O (2011) 'Vitamin D and its emerging role in immunopathology'. Clinical Rheumatology, . [Details]
Connolly M, Mullan RH, McCormick J, Matthews C, Sullivan O, Kennedy A, Fitzgerald O, Poole AR, Bresnihan B, Veale DJ, Fearon U (2011) 'A-SAA regulates TNFα and matrix turnover and predicts disease progression in patients pre/post biologic therapy'. Arthritis Rheumatology, . [Details]
Ng CT, Biniecka M, Kennedy A, McCormick J, Fitzgerald O, Bresnihan B, Buggy D, Taylor C (2010) 'Synovial tissue hypoxia and inflammation in vivo'. Annals of Rheumatic Diseases, 69 (7):1389-1395. [Details]
Martin, J,Walsh, C,Gibbs, A,McDonnell, T,Fearon, U,Keane, J,Codd, MB,Dodd, J,Veale, D,FitzGerald, O,Bresnihan, B; (2010) 'Comparison of interferon gamma release assays and conventional screening tests before tumour necrosis factor alpha blockade in patients with inflammatory arthritis'. Annals of the Rheumatic Diseases, 69 :181-185. [DOI] [Details]
Ritchlin CT, Qureshi AA, de Vlam K, Pitzalis C, Helliwell PS, Mease PJ, Gladman DD, Krueger GG, Kavanaugh AF, Fitzgerald O; (2010) 'Biomarkers in psoriasis and psoriatic arthritis: GRAPPA 2008'. Journal of Rheumatology, . [Details]
Gladman DD, Landewé R, McHugh NJ, Fitzgerald O, Thaci D, Coates L, Mease PJ, Qureshi AA, Krueger GG, Ritchlin CT, Kavanaugh AF, Garg A; (2010) 'Composite measures in psoriatic arthritis: GRAPPA 2008'. Journal of Rheumatology, . [Details]
Coates LC, McGonagle DM, Hodgson R, Gisondi P, Kavanaugh AF, Qureshi AA, Fitzgerald O, Mease PJ, Garg A, Rosen CF, Ridley D, Gladman DD, Krueger GG, Ritchlin CT, Helliwell PS; (2010) 'Imaging in psoriasis and psoriatic arthritis: GRAPPA 2008'. Journal of Rheumatology, . [Details]
FitzGerald O, Maksymowych WP; (2010) 'What are the spondyloarthropathies?'. Best Practice & Research Clinical Rheumatology, . [Details]
Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2, Strange A, Capon F, Spencer CC, Knight J, Weale ME, Allen MH, Barton A, Band G, Bellenguez C, Bergboer JG, Blackwell JM, Bramon E, Bumpstead SJ, Casas JP, Cork MJ, Corvin A, Deloukas P, Dilthey A, Duncanson A, Edkins S, Estivill X, FitzGerald O, Freeman C, Giardina E, Gray E, Hofer A, Hüffmeier U, Hunt SE, Irvine AD, Jankowski J, Kirby B, Langford C, Lascorz J, Leman J, Leslie S, Mallbris L, Markus HS, Mathew CG, McLean WH, McManus R, Mössner R, Moutsianas L, Naluai AT, Nestle FO, Novelli G, Onoufriadis A, Palmer CN, Perricone C, Pirinen M, Plomin R, Potter SC, Pujol RM, Rautanen A, Riveira-Munoz E, Ryan AW, Salmhofer W, Samuelsson L, Sawcer SJ, Schalkwijk J, Smith CH, Ståhle M, Su Z, Tazi-Ahnini R, Traupe H, Viswanathan AC, Warren RB, Weger W, Wolk K, Wood N, Worthington J, Young HS, Zeeuwen PL, Hayday A, Burden AD, Griffiths CE, Kere J, Reis A, McVean G, Evans DM, Brown MA, Barker JN, Peltonen L, Donnelly P, Trembath RC; (2010) 'A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1'. Nature Genetics, . [Details]
Prinz J, FitzGerald O, Boggs R, Foehl J, Robertson D, Pedersen R, Molta C, Freundlich B; (2010) 'Combination of skin, joint and quality of life outcomes with etanercept in psoriasis and psoriatic arthritis in the PRESTA trial'. . [Details]
Minnock P, Kirwan J, Veale D, Fitzgerald O, Bresnihan B; (2010) 'Fatigue is an independent outcome measure and is sensitive to change in patients with psoriatic arthritis'. Clinical and Experimental Rheumatology, . [Details]
Adams R, Walsh C, Veale D, Bresnihan B, FitzGerald O, Barry M; (2010) 'Understanding the relationship between the EQ-5D, SF-6D, HAQ and disease activity in inflammatory arthritis'. . [Details]
Mumtaz A, FitzGerald O; (2010) 'Application of the GRAPPA psoriatic arthritis treatment recommendations in clinical practice'. Current Rheumatology Report, . [Details]
Rooney T, Roux-Lombard P, Veale DJ, FitzGerald O, Dayer JM, Bresnihan B; (2010) 'Synovial tissue and serum biomarkers of disease activity, therapeutic response and radiographic progression: analysis of a proof-of-concept randomised clinical trial of cytokine blockade'. Annals of the Rheumatic Diseases, 69 (4):706-714. [DOI] [Details]
Tobin AM, Veale DJ, Fitzgerald O, Rogers S, Collins P, O'Shea D, Kirby B; (2010) 'Cardiovascular disease and risk factors in patients with psoriasis and psoriatic arthritis'. Rheumatology, 37 (7):1386-1394. [DOI] [Details]
Rooney T, Edwards CK 3rd, Gogarty M, Greenan L, Veale DJ, FitzGerald O, Dayer JM, Bresnihan B; (2010) 'Synovial tissue rank ligand expression and radiographic progression in rheumatoid arthritis: observations from a proof-of-concept randomized clinical trial of cytokine blockade'. Rheumatology International, 30 (12):1571-1580. [DOI] [Details]
Ng CT, Radovits BJ, Kievit W, Fransen J, van Riel PL, FitzGerald O, Veale DJ, Bresnihan B; (2010) 'Unregulated prescribing of anti-tumour necrosis factor agents does not mean inappropriate prescribing'. Annals of the Rheumatic Diseases, 69 (1):313-314. [DOI] [Details]
Connolly M, Marrelli A, Blades M, McCormick J, Maderna P, Godson C, Mullan R, FitzGerald O, Bresnihan B, Pitzalis C, Veale DJ, Fearon U; (2010) 'Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model'. Journal of Immunology, 184 (11):6427-6437. [DOI] [Details]
Bowes, J,Flynn, E,Ho, P,Aly, B,Morgan, AW,Marzo-Ortega, H,Coates, L,McManus, R,Ryan, AW,Kane, D,Korendowych, E,McHugh, N,FitzGerald, O,Packham, J,Bruce, IN,Barton, A; (2010) 'Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis'. Annals of the Rheumatic Diseases, 69 :2199-2203. [DOI] [Details]
Huffmeier, U,Uebe, S,Ekici, AB,Bowes, J,Giardina, E,Korendowych, E,Juneblad, K,Apel, M,McManus, R,Ho, P,Bruce, IN,Ryan, AW,Behrens, F,Lascorz, J,Bohm, B,Traupe, H,Lohmann, J,Gieger, C,Wichmann, HE,Herold, C,Steffens, M,Klareskog, L,Wienker, TF,FitzGerald, O,Alenius, GM,McHugh, NJ,Novelli, G,Burkhardt, H,Barton, A,Reis, A; (2010) 'Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis'. Nature Genetics, 42 :996-118. [DOI] [Details]
Saber, TP,Ng, CT,Renard, G,Lynch, BM,Pontifex, E,Walsh, CAE,Grier, A,Molloy, M,Bresnihan, B,FitzGerald, O,Fearon, U,Veale, DJ; (2010) 'Remission in psoriatic arthritis: is it possible and how can it be predicted?'. Arthritis Research and Therapy, 12 . [DOI] [Details]
Reid, A,Brady, A,Cusack, T,Blake, C,Mongey, AB,Veale, DJ,FitzGerald, O (2009) 'RCT EXAMINING THE EFFECTS OF EXERCISE FOR PEOPLE WITH RHEUMATOID ARTHRITIS ON ANTI-TNF alpha MEDICATION'. 48 :159-159. [Details]
Maksymowych WP, Fitzgerald O, Wells GA, Gladman DD, Landewe R, Ostergaard M, Taylor WJ, Christensen R, Tak PP, Boers M, Syversen SW, Bathon JM, Ritchlin CJ, Mease PJ, Mykerk VP, Garnero P, Geusens P, El-Gabalawy H, Aletaha D, Inman RD, Kraus VB, Kvien TK, van der Heijde D; (2009) 'Proposal for levels of evidence schema for validation of a soluable biomarker reflecting damage endpoints in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, and recommendations for study design'. Journal of Rheumatology, . [Details]
Doran JP, Alraqi S, Callanan I, Fitzgerald O, Bresnihan B, Veale DJ; (2009) 'An audit of hospital based outpatient infusions and a pilot program of community-based monoclonal antibody infusions'. IRISH JOURNAL OF MEDICAL SCIENCE, . [Details]
Martin J, Walsh C, Gibbs A, McDonnell T, Fearon U, Keane J, Codd MB, Dodd JD, Veale D, Fitzgerald O, Bresnihan B; (2009) 'Comparison of interferon-{gamma}-release assays and conventional screening tests before tumour necrosis factor-{alpha} blockade in patients with inflammatory arthritis'. Annals of Rheumatic Diseases, . [Details]
Fitzgerald O, Winchester R; (2009) 'Psoriatic arthritis: from pathogenesis to therapy'. Arthritis Research and Therapy, . [Details]
Becker K, Fitzgerald O, Green AJ, Keogan M, Newbury-Ecob R, Greenhalgh L, Withers S, Hollox EJ, Aldred PM, Armour JA; (2009) 'Constitutional trisomy 8 and Behçet syndrome'. American Journal of Medical Genetics, . [Details]
Rooney T, Roux-Lombard P, Veale DJ, Fitzgerald O, Dayer JM, Bresnihan B; (2009) 'Synovial tissue and serum biomarkers of disease activity, therapeutic response and radiographic progression. analysis of a proof-of-concept randomized clinical trial of cytokine blockade'. Annals of Rheumatic Diseases, . [Details]
Murphy G, Coughlan R, Devlin J, FitzGerald O, McCarthy G; (2009) 'Recommendations for the therapeutics of methotrexate in rheumatoid arthritis'. Irish Medical Journal, . [Details]
Pearman L, Last J, Fitzgerald O, Veale D, Joyce M, Rainford L, McEntee M, McNulty J, Thomas E, Ryan J, McGee A, Toomey D'Helft R, Lowe J, Brennan PC.; (2009) 'Rheumatoid arthritis: a novel radiographic projection for hand assessment'. British Journal of Radiology, 82 (979):554-60. Available Online [DOI] [Details]
Aherne CM, McMorrow J, Kane D, FitzGerald O, Mix KS and Murphy EP. ; (2009) ' Identification of the orphan receptor NR4A2 as a transcriptional regulator of IL-8 expression in human inflammatory arthritis'. Molecular immunology, 46 :3345-3357. [Details]
Maksymowych WP, Landewé R, Tak PP, Ritchlin CJ, Ostergaard M, Mease PJ, El-Gabalawy H, Garnero P, Gladman DD, Fitzgerald O, Aletaha D, Bykerk VP, Bathon JM, Syversen SW, Boers M, Geusens P, Inman RD, Kraus VB, Kvien TK, Taylor WJ, Wells GA, van der Heijde D; (2009) 'Reappraisal of OMERACT 8 draft validation criteria for a soluble biomarker reflecting structural damage endpoints in rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis: the OMERACT 9 v2 criteria'. Journal of Rheumatology, . [Details]
Syversen SW, Landewe R, van der Heijde D, Bathon JM, Boers M, Bykerk VP, Fitzgerald O, Gladman DD, Garnero P, Geusens P, El-Gabalawy H, Inman RD, Kraus V, Kvien TK, Mease PJ, Ostergaard M, Ritchlin CJ, Tak PP, Taylor WJ, Maksymowych WP; (2009) 'Testing of the OMERACT 8 draft validation criteria for a soluble biomarker reflecting structural damage in rheumatoid arthritis: a systematic literature search on 5 candidate biomarkers'. Journal of Rheumatology, . [Details]
Rooney T, Edwards CK 3rd, Gogarty M, Greenan L, Veale DJ, Fitzgerald O, Dayer JM, Bresnihan B; (2009) 'Synovial tissue rank ligand expression and radiographic progression in rheumatoid arthritis: observations from a proof-of-concept randomized clinical trial of cytokine blockade'. Rheumatology International, . [Details]
Van den Bosch F, Manger B, Goupille P, McHugh N, Rødevand E, Holck P, van Vollenhoven RF, Leirisalo-Repo M, Fitzgerald O, Kron M, Frank M, Kary S, Kupper H; (2009) 'Effectiveness of adalimumab in treating patients with active psoriatic arthritis and predictors of good clinical responses for arthritis, skin and nail lesions'. Annals of Rheumatic Diseases, . [Details]
French HP, Cusack T, Brennan A, White B, Gilsenan C, Fitzpatrick M, O'Connell P, Kane D, Fitzgerald O, McCarthy GM; (2009) 'Exercise and manual physiotherapy arthritis research trial (EMPART): a multicentre randomised controlled trial'. BMC Musculoskeletal Disorders, 10 . [DOI] [Details]
Murphy E, Roux-Lombard P, Rooney T, Fitzgerald O, Dayer JM, Bresnihan B; (2009) 'Serum levels of tissue inhibitor of metalloproteinase-1 and periarticular bone loss in early rheumatoid arthritis'. Journal of Clinical Rheumatology, 28 (3):285-291. [DOI] [Details]
Moran EM, Mullan R, McCormick J, Connolly M, Sullivan O, Fitzgerald O, Bresnihan B, Veale DJ, Fearon U; (2009) 'Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-alpha, Oncostatin M and response to biologic therapies'. Arthritis Research and Therapy, 11 (4). [DOI] [Details]
Bresnihan B, Pontifex E, Thurlings RM, Vinkenoog M, El-Gabalawy H, Fearon U, Fitzgerald O, Gerlag DM, Rooney T, van de Sande MG, Veale D, Vos K, Tak PP; (2009) 'Synovial tissue sublining CD68 expression is a biomarker of therapeutic response in rheumatoid arthritis clinical trials: consistency across centers'. Rheumatology, 36 (8):1800-1802. [DOI] [Details]
O'Kane, M,Markham, T,McEvoy, AN,Fearon, U,Veale, DJ,FitzGerald, O,Kirby, B,Murphy, EP; (2008) 'Increased expression of the orphan nuclear receptor NURR1 in psoriasis and modulation following TNF-alpha inhibition'. Journal of Investigative Dermatology, 128 :300-310. [DOI] [Details]
Murphy E, Roux-Lombard P, Rooney T, Fitzgerald O, Dayer JM, Bresnihan B; (2008) 'Serum levels of tissue inhibitor of metalloproteinase-1 and periarticular bone loss in early rheumatoid arthritis'. Clinical Rheumatology, . [Details]
Tanaka M, Nagai T, Tsuneyoshi Y, Sunahara N, Matsuda T, Nakamura T, Tsuyama S, Hasui K, FitzGerald O, Matsuyama T; (2008) 'Expansion of a unique macrophage subset in rheumatoid arthritis synovial lining layer'. Clinical Immunology, . [Details]
Ritchlin CT, Kavanaugh A, Gladman DD, Mease PJ, Helliwell P, Boehncke WH, de Vlam K, Fiorentino D, Fitzgerald O, Gottlieb AB, McHugh N, Nash PT, Qureshi A, Soriano ER, Taylor WJ; (2008) 'Treatment recommendations for psoriatic arthritis'. Annals of Rheumatic Diseases, . [Details]
Walsh CA, Fearon U, Fitzgerald O, Veale DJ, Bresnihan B.; (2008) 'Decreased CD20 expression in rheumatoid arthritis synovium following eight weeks of rituximab therapy'. Clinical and Experimental Rheumatology, . [Details]
de Vlam K, Gottlieb AB, Fitzgerald O.; (2008) 'Biological biomarkers in psoriatic disease. A review'. Journal of Rheumatology, . [Details]
McKenna MJ, van der Kamp S, Au-Yeong M, Fitzgerald O.; (2008) 'Improving standards of DXA'. The Irish Medical Journal, . [Details]
Callaly EL, Fitzgerald O, Rogers S. ; (2008) 'Hydroxychloroquine-associated, photo-induced toxic epidermal necrolysis'. Clinical and Experimental Dermatology, . [Details]
Murphy E, Bresnihan B, Fitzgerald O.; (2008) 'Measurement of periarticular bone mineral density in the hands of patients early inflammatory arthritis using dual energy x-ray absorptiometry'. Clinical Rheumatology, . [Details]
Walsh CA, Mullan RH, Minnock PB, Slattery C, Fitzgerald O, Bresnihan B.; (2008) 'Consistency in assessing the Disease Activity Score-28 in routine clinical practice'. Annals of the Rheumatic Diseases, . [Details]
Patterson AM, Cartwright A, David G, Fitzgerald O, Bresnihan B, Ashton BA, Middleton J.; (2008) 'Differential expression of syndecans and glypicans in chronically inflamed synovium'. Annals of the Rheumatic Diseases, . [Details]
Coates LC, Anderson RR, Fitzgerald O, Gottlieb AB, Kelly SG, Lubrano E, McGonagle DG, Olivieri I, Ritchlin CT, Tan AL, De Vlam K, Helliwell PS.; (2008) 'Clues to the pathogenesis of psoriasis and psoriatic arthritis from imaging: a literature review'. Journal of Rheumatology, . [Details]
Pearman L, FitzGerald O, Veale D, Joyce M, Rainford L, McNulty J, Thomas E, Ryan J, Toomey, R, Lowe J, Brennan PC. ; (2008) 'Rheumatoid Arthritis: the UCD projection for hand and wrist assessment, a novel technique'. British Journal of Radiology, . [Details]
Mullan RH, Matthews C, Bresnihan B, FitzGerald O, King L, Poole AR, Fearon U, Veale DJ; (2007) 'Early changes in serum type II collagen biomarkers predict radiographic progression at one year in inflammatory arthritis patients after biologic therapy'. Arthritis and Rheumatism, 56 (9):2919-2928. [DOI] [Details]
Gladman DD, Mease PJ, Strand V, Healy P, Helliwell PS, Fitzgerald O, Gottlieb AB, Krueger GG, Nash P, Ritchlin CT, Taylor W, Adebajo A, Braun J, Cauli A, Carneiro S, Choy E, Dijkmans B, Espinoza L, van der Heijde D, Husni E, Lubrano E, McGonagle D, Qureshi A, Soriano ER, Zochling J.; (2007) 'Consensus on a core set of domains for psoriatic arthritis'. Journal of Rheumatology, 34 (5):1167-1170. [Details]
Zhao Y, Terron-Kwiatkowski A, Liao H, Lee SP, Allen MH, Hull PR, Campbell LE, Trembath RC, Capon F, Griffiths CE, Burden D, McManus R, Hughes R, Kirby B, Rogers SF, Fitzgerald O, Kane D, Barker JN, Palmer CN, Irvine AD, Irwin McLean WH.; (2007) 'Filaggrin Null Alleles Are Not Associated with Psoriasis'. Journal of Investigative Dermatology, . [Details]
Bresnihan B, Gerlag DM, Rooney T, Smeets TJ, Wijbrandts CA, Boyle D, Fitzgerald O, Kirkham BW, McInnes IB, Smith M, Ulfgren AK, Veale DJ, Tak PP.; (2007) 'Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: standardization and consistency across centers'. Journal of Rheumatology, 34 (3):620-622. [Details]
O'Kane M, Markham T, Mc Evoy TN, Fearon U, Veale DJ, Fitzgerald O, Kirby B, Murphy EP. ; (2007) 'Increased expression of the orphan nuclear receptor NURR1 in psoriasis and modulation following TNF-alpha inhibition'. Journal of Investigative Dermatology, . [Details]
Gladman DD, Mease PJ, Healy P, Helliwell PS, Fitzgerald O, Cauli A, Lubrano E, Krueger GG, van der Heijde D, Veale DJ, Kavanaugh A, Nash P, Ritchlin C, Taylor W, Strand V.; (2007) 'Outcome measures in psoriatic arthritis'. Journal of Rheumatology, 34 (5):1159-1166. [Details]
Gogarty M, Fitzgerald O.; (2007) 'Immunohistochemistry of the inflamed synovium'. Methods in Molecular Medicine, . [Details]
Kennedy, N., Stokes, E., O'Shea, E., Murphy, T.B., Bresnihan, B. and FitzGerald, O.; (2007) 'Inpatient and Outpatient Rehabilitation for Patients with Rheumatoid Arthritis: A Clinical and Economic Assessment'. Journal of Medical Economics, 10 (4):515-528. [DOI] [Details]
Walsh CA, Minnock P, Slattery C, Kennedy N, Pang F, Veale DJ, Bresnihan B, Fitzgerald O.; (2007) 'Quality of life and economic impact of switching from established infliximab therapy to adalimumab in patients with rheumatoid arthritis'. Journal of Rheumatology, 46 (7):1148-1152. [Details]
Patterson AM, Cartwright A, David G, Fitzgerald O, Bresnihan B, Ashton BA, Middleton JF.; (2007) 'Differential expression of syndecans and glypicans in chronically inflamed synovium'. Annals of Rheumatic Diseases, . [Details]
Ralph, JA, Zocco, D, Bresnihan, B, FitzGerald, O, McEvoy, AN, Murphy, EP, ; (2007) 'A role for type 1 alpha corticotropin-releasing hormone receptors in mediating local changes in chronically inflamed tissue'. American Journal of Pathology, 170 :1121-1133. [Details]
Brulhart, L., Ng, C. T., Codd, M. B., Walsh, C. A. E., Pontifex, E. K., Lynch, B., Grier, A., Molloy, M., O'Flynn, E., Bresnihan, B., FitzGerald, O., Veale, D. J., ; (2007) 'Co-medication with methotrexate is not associated with remission in psoriatic arthritis patients on TNFI inhibitors treatment'. Arthritis and Rheumatism, 56 (12):4298-4299. [Details]
Allen, MH; Zhao, Y; Terron-Kwiatkowski, A; Liao, H; Lee, SP; Hull, PR; Campbell, LM; Trembath, RC; Capon, F; ORegan, G; Griffiths, CEM; Burden, D; McManus, R; Hughes, R; Kirby, B; Fitzgerald, O; Kane, D; Irvine, AD; Palmer, CNA; Barker, JNWN; McLean, WHI; ; (2007) 'Psoriasis shows no association with laggrin-null alleles'. British Journal of Dermatology, 156 :1111-1111. [Details]
Markham T, Mathews C, Rogers S, Mullan R, Bresnihan B, Fitzgerald O, Veale DJ, Fearon U.; (2006) 'Downregulation of the inhibitor of apoptosis protein survivin in keratinocytes and endothelial cells in psoriasis skin following infliximab therapy'. British Journal of Dermatology, 155 (6):1191-1196. [Details]
Mullan, R.H., Bresnihan, B., Golden-Mason, L., Markham, T., O'Hara, R., FitzGerald, O., Veale, D.J. Fearon, U.; (2006) 'Acute-phase serum amyloid A Stimulation of angiogenesis, leukocyte recruitmetn, and matrix degradation in rheumatoid arthritis through and NF-kappaB-dependent signal transduction pathway'. ARTHRITIS AND RHEUMATISM, . [Details]
Gardner, L., Wilson, C., Patterson, A.M., Bresnihan, B., FitzGerald, O., Stone, M.A., Ashton, B.A. Middleton, J.; (2006) 'Temporal expression pattern of Duffy antigen in rheumatoid arthritis: up-regulation in early disease'. ARTHRITIS AND RHEUMATISM, . [Details]
Smith MD, Baeten D, Ulfgren AK, McInnes IB, Fitzgerald O, Bresnihan B, Tak PP, Veale D; (2006) 'OMERACT synovial special interests group. Standardisation of synovial tissue infiltrate analysis: how far have we come? How much further do we need to go?'. Annals of Rheumatic Diseases, 65 (1):93-100. [Details]
Kruithof, E., De Rycke, L., Vandooren, B., De Keyser, F., FitzGerald, O., McInnes, I., Tak, PP., Bresnihan, B., Veys, EM., Baeten, D.; (2006) 'Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis'. ARTHRITIS AND RHEUMATISM, . [Details]
Markham T, Mullan R, Golden-Mason L, Rogers S, Bresnihan B, Fitzgerald O, Fearon U, Veale DJ. ; (2006) 'Resolution of endothelial activation and down-regulation of Tie2 receptor in psoriatic skin after infliximab therapy'. Journal of the American Academy of Dermatology, 54 :1003-1012. [Details]
Matthews C, Rogers S, FitzGerald O. ; (2006) 'Development of new-onset psoriasis while on anti-TNF alpha treatment'. Annals of the Rheumatic Diseases, 65 :1529-1530. [Details]
FitzGerald O, McInnes I.; (2006) 'Spondyloarthropathy: disease at the crossroads of immunity'. Best Practice & Research Clinical Rheumatology, 20 (5):949-967. [Details]
Fitzgerald O, Dougados M.; (2006) 'Psoriatic arthritis: one or more diseases?'. Best Practice & Research Clinical Rheumatology, 20 (3):435-450. [Details]
Smith MD, Baeten D, Ulfgren AK, McInnes IB, Fitzgerald O, Bresnihan B, Tak PP, Veale D; OMERACT synovial special interests group.; (2006) 'Standardisation of synovial tissue infiltrate analysis: how far have we come? How much further do we need to go?'. Annals of Rheumatic Diseases, 65 (1):93-100. Available Online [Details]
Matthews C, Fitzgerald O.; (2006) 'Seropositive erosive rheumatoid arthritis (RA)'. Journal of Rheumatology, 45 (9):1100. [Details]
Fearon U, Mullan R, Markham T, Connolly M, Sullivan S, Poole AR, FitzGerald O, Bresnihan B, Veale DJ.; (2006) 'Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures'. Arthritis and Rheumatism, 54 (10):3152-3162. [Details]
Smith, M.D., Baeten, D., Ulfgren, A.K., McInnes, I.B., Fitzgerald, O., Bresnihan, B., Tak, P.P., Veale D.J.; (2005) 'Standardisation of synovial tissue infiltrate analysis: how far have we come? How much further do we need to go?'. ANNALS OF RHEUMATIC DISEASES, . [Details]
Kee F, Sheehy N, O'Hare L, Bane C, Bell A, Dempster M, FitzGerald O.; (2005) 'Rheumatologists' judgements about the efficacy of anti-TNF therapy in two neighbouring regions'. Journal of Rheumatology, 44 (11):1407-1413. Available Online [Details]
Manzo A, Paoletti S, Carulli M, Blades MC, Barone F, Yanni G, Fitzgerald O, Bresnihan B, Caporali R, Montecucco C, Uguccioni M, Pitzalis C.; (2005) 'Systematic microanatomical analysis of CXCL13 and CCL21 in situ production and progressive lymphoid organization in rheumatoid synovitis'. European Journal of Immunology, 35 (5):1347-1359. Available Online [Details]
Veale DJ, Ritchlin C, FitzGerald O.; (2005) 'Immunopathology of psoriasis and psoriatic arthritis'. Annals of the Rheumatic Diseases, 64 Suppl. 2 (ii):26-29. Available Online [Details]
Fitzgerald O.; (2005) 'Psoriatic arthritis synovial histopathology: commentary on the article by Kruithof and colleagues'. Arthritis Research and Therapy, 7 (3):124-125. [Details]
Ralph, J., McEvoy, A., Kane, D., Bresnihan, B., FitzGerald, O. & Murphy, E.P.; (2005) 'Modulation of orphan nuclear receptor NURR1 expression by methotrexate in human inflammatory joint disease involves adenosine A2A receptor mediated responses'. JOURNAL OF IMMUNOLOGY, 175 (1):555-565. [Details]
Benito MJ, Murphy E, Murphy E, FitzGerald O, van den Berg W, Bresnihan B.; (2004) 'Increased NF-kB1 (p50) expression at sites adjacent to the cartilage-pannus junction in rheumatoid arthritis'. Arthritis and Rheumatism, 50 :1788-1799. [Details]
McEvoy A, Bresnihan B, FitzGerald O and Murphy E.; (2004) 'COX-2-derived prostaglandin E2 production by CRH contributes to the activated cAMP Response Element Binding Protein (CREB) content in Rheumatoid Arthritis synovial tissue'. Arthritis and Rheumatism, 50 :1132-1145. [Details]
OHara R, Murphy E, Whitehead A.S., FitzGerald O. and Bresnihan B.; (2004) 'Local expression of the serum amyloid A and formyl peptide receptor-like 1 genes in synovial tissue is associated with matrix metalloproteinase production in patients with inflammatory arthritis'. Arthritis and Rheumatism, 50 :1781-1787. [Details]
Real, KJ; Kane, D; Duffy, T; FitzGerald, O; Masterson, BF; ; (2003) 'The contact system in inflammatory arthritis'. Arthritis and Rheumatism, 48 (9):318-318. [Details]
Minnock, P,FitzGerald, O,Bresnihan, B; (2003) 'Women with established rheumatoid arthritis perceive pain as the predominant impairment of health status'. Rheumatology, 42 :995-1000. [DOI] [Details]
Balding, J,Kane, D,Livingstone, W,Mynett-Johnson, L,Bresnihan, B,Smith, O,FitzGerald, O; (2003) 'Cytokine gene polymorphisms - Association with psorlatic arthritis susceptibility and severity'. Arthritis and Rheumatism, 48 :1408-1413. [DOI] [Details]
Ralph, JA; Bresnihan, B; FitzGerald, O; Murphy, EP; ; (2003) 'Methotrexate inhibits the production of the transcription factor NURR1 in human inflammatory joint disease'. Arthritis and Rheumatism, 48 (9):417-417. [Details]
Gallagher J, Howlin J, Mc Carthy C, Murphy E, Bresnihan B, FitzGerald O, Godson C, Brady HR and Finian Martin.; (2003) 'Identification of Naf1/ABIN-1 among TNF-alpha-induced expressed genes in human synoviocytes using oligonucleotide microarrays'. FEBS Letters, 551 :8-12. [Details]
Duffy T, Belton O, Bresnihan B, FitzGerald O, FitzGerald D; (2003) 'Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis'. Drugs, 63 (Suppl 1):31-36. [Details]
Veale, D; FitzGerald, O; ; (2002) 'Psoriatic arthritis'. Best Practice and Research in Clinical Rheumatology, 16 (4):523-535. [Details]
McEvoy A, Conneely O.M., Bresnihan B., FitzGerald O and Murphy E.; (2002) 'Activation of nuclear orphan receptor NURR1 transcription by NFkB and CREB in rheumatoid arthritis synovial tissue'. Immunology, 168 :2979-2987. [Details]
McEvoy A., Bresnihan B, FitzGerald O and Murphy E.; (2002) 'Corticotropin-Releasing Hormone signaling in vascular endothelium is mediated through the cAMP/CREB pathway'. Annals of the New York Academy of Sciences, 966 :119-130. [Details]
Cunnane G,Fitzgerald O, Beeton C, Cawston TE, Bresnihan B ; (2001) 'Early joint erosions and serum levels of matrix metalloproteinase 1, matrix metalloproteinase 3, and tissue inhibitor of metalloproteinases 1 in rheumatoid arthritis'. Arthritis and Rheumatism, 44 (10):2263-2274. [Details]
Murphy E, McEvoy A, Conneely OM, Bresnihan B and Fitzgerald O.; (2001) 'Involvement of the nuclear orphan receptor NURR1 in the regulation of Corticotropin Releasing Hormone expression and actions in human inflammatory arthritis'. Arthritis and Rheumatism, 44 :782-793. [Details]
McEvoy A, Bresnihan B, FitzGerald O and Murphy E.; (2001) 'Corticotropin Releasing Hormone (CRH) signaling in synovial tissue from patients with early inflammatory arthritis is mediated by the type 1a CRH receptor'. Arthritis and Rheumatism, 44 :1761-1767. [Details]
Cunnane, G., Grehan, S., Geoghegan, S., McCormack, C., Shields, D., Whitehead, A. S., Bresnihan, B., Fitzgerald, O. (2000) 'Serum amyloid A in the assessment of early inflammatory arthritis'. J Rheumatol, 27 (1):58-63. Available Online [Details]
R OHara, EP Murphy, A S Whitehead, O FitzGerald, B Bresnihan.; (2000) 'Acute phase serum amyloid A production by rheumatoid arthritis synovial tissue'. Arthritis Care and Research, 2 :142-144. [Details]
Youssef, PP,Kraan, M,Breedveld, F,Bresnihan, B,Cassidy, N,Cunnane, G,Emery, P,Fitzgerald, O,Kane, D,Lindblad, S,Reece, R,Veale, D,Tak, PP; (1998) 'Quantitative microscopic analysis of inflammation in rheumatoid arthritis synovial membrane samples selected at arthroscopy compared with samples obtained blindly by needle biopsy'. Arthritis and Rheumatism, 41 :663-669. [Details]
Bresnihan, B; Cunnane, G; Youssef, P; Yanni, G; Fitzgerald, O; Mulherin, D; ; (1998) 'Microscopic measurement of synovial membrane inflammation in rheumatoid arthritis: Proposals for the evaluation of tissue samples by quantitative analysis'. British Journal of Rheumatology, 37 (6):636-642. [Details]
Youssef, PP; Smeets, TJM; Bresnihan, B; Cunnane, G; Fitzgerald, O; Breedveld, F; Tak, PP; ; (1998) 'Microscopic measurement of cellular infiltration in the rheumatoid arthritis synovial membrane: A comparison of semiquantitative and quantitative analysis'. British Journal of Rheumatology, 37 (9):1003-1007. [Details]
Kane, D; Fitzgerald, O; ; (1998) 'Ultrasound guided injection of plantar fasciitis - Reply'. Annals of the Rheumatic Diseases, 57 (12):750-750. [Details]
Youssef, PP; Roth, J; Costello, P; Cassidy, N; Cunnane, G; FitzGerald, O; Bresnihan, B; ; (1997) 'Differential expression of MRP8, MRP14 and the MRP8/14 heterodimer at the cartilage-pannus junction compared with other sites in rheumatoid arthritis (RA) synovium'. Arthritis and Rheumatism, 40 (9):1325-1325. [Details]
Mulherin, D; FitzGerald, O; Bresnihan, B; ; (1997) 'Clinical improvement and radiological deterioration in rheumatoid arthritis - Reply'. British Journal of Rheumatology, 36 (11):1232-1232. [Details]
Cunnane, G; FitzGerald, O; Hummel, KM; Youssef, P; Kane, D; Gay, RE; Gay, S; Bresnihan, B; ; (1997) 'Detection of collagenase, cathepsin B and cathepsin L messenger RNA expression in synovial tissues of patients with early inflammatory arthritis'. Arthritis and Rheumatism, 40 (9):600-600. [Details]
Mulherin, D; FitzGerald, O; Bresnihan, B; ODonoghue, D; McCarthy, D; ; (1997) 'Hypochromic red cells as an indicator of iron deficiency - Reply'. Rheumatology, 24 (4):805-805. [Details]
Youssef, PP; Breedveld, FC; Bresnihan, B; Cassidy, N; Cunnane, G; Emery, P; FitzGerald, O; Kane, D; Kraan, M; Lindblad, S; Reece, R; Veale, D; Tak, PP; ; (1997) 'Quantitative microscopic analysis of inflammation in rheumatoid arthritis synovial membrane samples selected at arthroscopy compared with samples taken blindly by needle biopsy'. Arthritis and Rheumatism, 40 (9):1555-1555. [Details]
Yuossef, PP; Smeets, TJ; Eresnihan, B; Cunnane, G; FitzGerald, O; Breedveld, F; Kraan, M; Tak, PP; ; (1997) 'Microscope measurement of inflammation in rheumatoid arthritis synovial membrane: A comparison of two methods'. Arthritis and Rheumatism, 40 (9):1554-1554. [Details]
Mulherin, DM; Veale, DJ; Belch, JJF; Bresnihan, B; Fitzgerald, O; ; (1996) 'Adhesion molecule in untreated inflammatory arthritis'. Qjm-An International Journal Of Medicine, 89 (3):195-203. [Details]
Cunnane, G; Brophy, DP; Gibney, RG; FitzGerald, O; ; (1996) 'Diagnosis and treatment of heel pain in chronic inflammatory arthritis using ultrasound'. Seminars in Arthritis and Rheumatism, 25 (6):383-389. [Details]
Mulherin, D; Fitzgerald, O; Bresnihan, B; ; (1996) 'Synovial tissue macrophage populations and articular damage in rheumatoid arthritis'. Arthritis and Rheumatism, 39 (1):115-124. [Details]
Cunnane, G; Summers, C; Taylor, D; Cawston, T; Bresnihan, B; FitzGerald, O; ; (1996) 'Elevated serum and synovial fluid levels of collagenase, stromelysin and tissue inhibitor of metalloproteinases (TIMP-1) in early inflammatory arthritis'. Arthritis and Rheumatism, 39 (9):630-630. [Details]
Mulherin, D,Fitzgerald, O,Bresnihan, B; (1996) 'Synovial tissue macrophage populations and articular damage in rheumatoid arthritis'. Arthritis and Rheumatism, 39 :115-124. [Details]
Mulherin, D; Fitzgerald, O; Bresnihan, B; ; (1996) 'Clinical improvement and radiological deterioration in rheumatoid arthritis: Evidence that the pathogenesis of synovial inflammation and articular erosion may differ'. British Journal of Rheumatology, 35 (12):1263-1268. [Details]
FITZGERALD, O; BRESNIHAN, B; ; (1995) 'SYNOVIAL-MEMBRANE CELLULARITY AND VASCULARITY'. Annals of the Rheumatic Diseases, 54 (6):511-515. [Details]
MARTIN, K; TALUKDER, R; MULHERIN, D; FITZGERALD, O; AXFORD, JS; ; (1995) 'IMMUNOGLOBULIN-G ASSOCIATED OLIGOSACCHARIDES IN ANKYLOSING-SPONDYLITIS, PSORIATIC AND RHEUMATOID-ARTHRITIS - SIMILARITIES AND DIFFERENCES'. Arthritis and Rheumatism, 38 (9):1016-1016. [Details]
MULHERIN, D; BRESNIHAN, B; FITZGERALD, O; ; (1995) 'DIGITAL DENERVATION ASSOCIATED WITH ABSENCE OF NAIL AND DISTAL INTERPHALANGEAL JOINT INVOLVEMENT IN PSORIATIC-ARTHRITIS'. Rheumatology, 22 (6):1211-1212. [Details]
MULHERIN, D; FITZGERALD, O; BRESNIHAN, B; ; (1995) 'MECHANISMS OF ARTICULAR DESTRUCTION IN THE FEET AND HANDS MAY DIFFER'. Arthritis and Rheumatism, 38 (9):1054-1054. [Details]
MULHERIN, D; FITZGERALD, O; BRESNIHAN, B; ; (1995) 'DISTRIBUTION OF MACROPHAGE POPULATIONS IN RHEUMATOID SYNOVIUM - EVIDENCE FOR MACROPHAGE MATURATION IN LINING LAYER'. Arthritis and Rheumatism, 38 (9):381-381. [Details]
MULHERIN, D; FITZGERALD, O; BRESNIHAN, B; ; (1993) 'RADIOLOGIC PROGRESSION IN RHEUMATOID-ARTHRITIS OVER 6-YEARS CORRELATES WITH MACROPHAGE NUMBERS IN THE SYNOVIUM'. British Journal of Rheumatology, 32 (NA):8-8. [Details]
CROWLEY, JJ,DONNELLY, SM,TOBIN, M,FITZGERALD, O,BRESNIHAN, B,MAURER, BJ,QUIGLEY, PJ; (1993) 'DOPPLER-ECHOCARDIOGRAPHIC EVIDENCE OF LEFT-VENTRICULAR DIASTOLIC DYSFUNCTION IN ANKYLOSING-SPONDYLITIS'. American Journal of Cardiology, 71 :1337-1340. [Details]
MULHERIN, D; HEFFERNAN, M; BRESNIHAN, B; FITZGERALD, O; ; (1993) 'SOLUBLE E-SELECTIN LEVELS IN SERUM AND SYNOVIAL-FLUID FROM PATIENTS WITH PSORIATIC AND OTHER INFLAMMATORY ARTHROPATHIES'. British Journal of Rheumatology, 32 (NA):26-26. [Details]
MULHERIN, DM; FITZGERALD, O; BRESNIHAN, B; ; (1993) 'LYMPHEDEMA OF THE UPPER LIMB IN PATIENTS WITH PSORIATIC-ARTHRITIS'. Seminars in Arthritis and Rheumatism, 22 (5):350-356. [Details]

Other Journals

Smith, M.D., Baeten, D., Ulfgren, A.K., McInnes, FitzGerald, O., Bresnihan, B., Tak, P.P. Veale, D.; (2006) 'Standardisation of synovial tissue infiltrate analysis: how far have we come? How much farther do we need to go? OMERACT 7 synovial special interest group: Review' Annals of the Rheumatic Diseases . [Details]
Bresnihan, B., Baeten, D., Firestein, G.S., FitzGerald, O.M., Gerlag, D.M., Haringman, J.J., McInnes, I.B., Reece, R.J., Smith, M.D., Ulfgren, A.K., Veale, D.J. Tak, P.P.; (2005) 'Synovial tissue analysis in clinical trials: OMERACT 7 Special Interest Group: Review' Journal of Rheumatology . [Details]
Markham, T., Mullan, R., Golden-Mason, L., Rogers, S., Bresnihan, B., FitzGerald, O., Fearon, U. Veale, D.J.; (2005) 'Resolution of endothelial activation and down-regulation of Tie2 receptor in psoriatic skin after infliximab therapy' J Am Acad Dermatol . [Details]
Kennedy N., Murphy B., Stokes E.K. and Fitzgerald O.; (2003) 'A randomised trial of inpatient versus outpatient care for patients with rheumatoid arthritis' Journal of Rheumatology 42 (Suppl 1) :93-93. [Details]
Kennedy, N., Murphy, B., Fitzgerald, O., Stokes, E.; (2001) 'A pilot study of a randomised trial of inpatient versus outpatient care for patients with rheumatoid arthritis' Physiotherapy Ireland 22 (1) :24-25. [Details]

Conference Publications

O'Kane, M., Murphy, E., Fitzgerald, O., McEvoy, A. & Kirby, B.; Corticotropin-releasing hormone (CRH), CRH receptor (CRH-R) and NURR1 are increased in psoriasis, further evidence of a brain-skin axis? British Journal of Dermatology [Details]
Gogarty, M., Murphy, E.P., Veale, D., Bresnihan, B., FitzGerald, O.; Alternative splicing of the VEGFR-1 (flt-1) and its ligands in human inflammatory arthritis ARTHRITIS AND RHEUMATISM [Details]
Stephenson A, Blake C, McKenna M, van der Kamp S, Cunningham C, Fitzgerald O, McCarthy Persson U (2012) The effects of exercise and vibration training on balance in postmenopausal women with osteopenia or osteoporosis- A randomised controlled pilot trial RTRS 2012: Rehabilitation and Therapy Research Society 8th Annual Conference: Promoting Health and Wellbeing: A Therapy Perspective [Details]
Reid A., Brady A., Mongey A., Veale D.J., FitzGerald O., Blake C., Cusack T.; (2011) EFFECT OF DYNAMIC EXERCISE ON FUNCTION IN PEOPLE WITH RHEUMATOID ARTHRITIS TAKING ANTI-TNF MEDICATION: RESULTS OF A RCT World Confederation for Physical Therapy Amsterdam, , 20-JUN-11 - 23-JUN-11 [Details]
French H., Cusack T., Brennan A. Caffrey A., Cuddy V., Fitzpatrick M., FitzGerald O., Gilsenan C., Kane D., O'Connell P., White B.6, McCarthy G.; (2011) THE EFFECTIVENESS OF EXERCISE WITH AND WITHOUT MANUAL THERAPY FOR HIP OSTEOARTHRITIS: PRELIMINARY RESULTS OF A MULTI-CENTRE RANDOMISED CONTROLLED TRIAL World Confederation for Physical Therapy Amsterdam, , 20-JUN-11 - 23-JUN-11 [Details]
Ryan J, NG CT, Gibney R, Fitzgerald O, Brennan P, Hefferenan E, Fearon U, McNulty J, Rainford L, Veale D; (2010) Novel PET/MR Fusion Imaging and Quantification of Knee Synovitis in Rheumatoid Arthritis American College of Rheumatology Annual Scientific Meeting Atlanta, USA, Available Online [Details]
Reid A, Brady A, Cusack T, Blake C, Monget AB, Veale D, FitzGerald O.; (2010) Improvements in Function Following Dynamic Exercise in Patients with RA taking anti-TNFα Therapy Reflected in Lower Limb Function Tests but not the HAQ American College of Rheumatologists Atlanta, USA, , 08-NOV-10 - 13-NOV-10 [Details]
Bresnihan, B,Pontifex, E,Thurlings, RM,Vinkenoog, M,El-Gabalawy, H,Fearon, U,Fitzgerald, O,Gerlag, DM,Rooney, T,van de Sande, MG,Veale, D,Vos, K,Tak, PP (2009) JOURNAL OF RHEUMATOLOGY Synovial Tissue Sublining CD68 Expression Is a Biomarker of Therapeutic Response in Rheumatoid Arthritis Clinical Trials: Consistency Across Centers , pp.1800-1802 [DOI] [Details]
McCormack, K.; Fitzgerald, D.; O'Huiginn, B.; Fitzgerald, O.; Smyth, B.; Caulfield, B.; (2009) Comparison of a computer game based exercise system with conventional approaches of exercise therapy in rheumatology patients British Society of Rheumatology 2009 Meeting [Details]
O'Kane, M., Markham, T., McEvoy, A. N., Fearon, U., Veale, D. J., FitzGerald, O., Kirby, B., Murphy, E. P., ; (2008) Journal of Investigative Dermatology Increased expression of the orphan nuclear receptor NURR1 in psoriasis and modulation following TNF-alpha inhibition , pp.300-310 [Details]
Gogarty, M, Murphy, EP, Fearon, U, Veale, DJ, Bresnihan, B, FitzGerald, O, ; (2007) ANN RHEUM DIS Placenta growth factor (PLGF) expression in inflammatory arthritis , pp.35-36 [Details]
Gogarty, M., Murphy, E. P., Fearon, U., Veale, D. J., Bresnihan, B., FitzGerald, O., ; (2007) Annals of the Rheumatic Diseases Abundant placenta growth factor (PlGF) expression in the inflammatory joint , pp.141-141 [Details]
Bresnihan, B,Gerlag, DM,Rooney, T,Smeets, TJM,Wijbrandts, CA,Boyle, D,Fitzgerald, O,Kirkham, BW,McInnes, IB,Smith, M,Ulfgren, AK,Veale, DJ,Tak, PP (2007) JOURNAL OF RHEUMATOLOGY Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: Standardization and consistency across centers , pp.620-622 [Details]
Garraud C, Ryan J, Carr H, Gibney R, Veale D, Fitzgerald O, Brennan PC; (2007) A volumetric reconstruction method for semi-automatic quantification of rheumatoid arthritis within the knee Virtual Reality Interactions and Physical Simulations [Details]
O'Kane, M., Kirby, B., FitzGerald, O. & Murphy, E.P.; (2006) Corticotropin-releasing hormone, corticotropin-releasing hormone receptor and NURR1 are increased in psoriasis lesional skin British Journal of Dermatology , pp.155 (1): 254-255 [Details]
Gogarty, M., Murphy, E.P., Veale, D., Bresnihan, B., FitzGerald, O.; (2005) Alternative splicing of the VEGFR-1 (flt-1) and its ligands in human inflammatory arthritis ARTHRITIS AND RHEUMATISM , pp.S52-S52 38 [Details]
Sweeney, C., Cahill, P.A., Bresnihan, B., FitzGerald, O. Fearon, U.; (2005) Inflammatory Arthritis American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
O'Rourke, M., FitzGerald, O., Bresnihan, B., Rogers-Gray, B., Winstone, J.M., Buchan, S. Veale, D.; (2005) Infliximab use in psoriatic arthritis : Clinical effectivemess and impact on quality of life American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Walsh, C., Mullan, R., Minnock, P., Slattery, C., FitzGerald, O. Bresnihan, B.; (2005) Reproducibility of the DAS28 in clinical practice American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Sweeney, C., Cahill, P.A., Mullan, R., Connolly, M., Bresnihan, B., FitzGerald, O., Fearon, U. Veale, D.J.; (2005) A role for the survivin and notch signalling pathways in blood vessel maturation and synovial hyperplasia in RA American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Walsh, C., O'Farrelly, C., Golden-Mason, L., Veale, D., FitzGerald, O., Bresnihan, B. Veale, D.; (2005) Expansion of T cells expressing CD94/NKG2A in patients with rheumatoid arthritis in clinical remission following treatment with anti-TNF alpha agents American Colelge of Rheumatology AGM [Details]
Connolly, M., Mullan, R., Sweeney, C., FitzGerald, O., Bresnihan, B., Veale, D.J. Fearon, U.; (2005) A-SAA induces chemokine expression, cell invasion and cytoskeletal disassembly in RA synovial tissue in part through P13 kinase pathway American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Gibbs, A., FitzGerald, O., Bresnihan, B. Veale, D.; (2005) A review of the use of magnetic resonance imaging (MRI) to diagnose spondylarthropathy early American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Mullan, R., Bresnihan, B., Sweeney, C., Connolly, M., FitzGerald, O., Veale, D. Fearon, U.; (2005) A novel role for the HDL receptor CLA-1 in synovial inflammation through serum amyloid A and apoprotein A-1 American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Mullan, R., Mathews, C., Lobanok, T., Kind, L., Walsh, C., FitzGerald, O., Bresnihan, B., Fearon, U., Poole, R. Veale, D.; (2005) Serum type II collagen epitope measurement predicts radiographic progression during treatment with anti-TNF alpha therapy American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Rooeny, T., Roux-Lombard, P., Veale, D.J., FitzGerald, O., Dayer, J.-M. Bresnihan, B.; (2005) Serum biomarkers of disease activity and radiographic progression in patients receiving biologic therapies for rheumatoid arthritis American Colelge of Rheumatology AGM , 12-NOV-05 - 17-NOV-05 [Details]
Martin, J., FitzGerald, O., Veale, D., McDonnell, T. Bresnihan, B.; (2005) Screening for latent tuberculosis infection prior to anti-TNF alpha treatment American Colelge of Rheumatology AGM [Details]
Ralph J, McEvoy A, Kane D, Bresnihan B, FitzGerald O and Murphy E; (2004) Modulation of orphan nuclear receptor NURR1 expression by methotrexate in human inflammatory joint disease involves adenosine A2A receptor mediated responses ARTHRITIS AND RHEUMATISM , pp.46 (9): 740 [Details]
Ralph JA, McEvoy AN, Bresnihan B, FitzGerald O and Murphy E. ; (2002) Modulation of type 1 CRH receptor expression by inflamed human synovial tissue: Involvement in the pathological changes associated with increased vascular permeability ARTHRITIS AND RHEUMATISM , pp.45 (9): 740 [Details]
McEvoy A, Bresnihan B, FitzGerald O and Murphy E. ; (2002) COX-2-derived prostaglandin E2 production by CRH contributes to the activated cAMP Response Element Binding Protein (CREB) content in Rheumatoid Arthritis synovial tissue ARTHRITIS AND RHEUMATISM , pp.45 (9): 740 [Details]
FITZGERALD, O,BRESNIHAN, B (1995) ANNALS OF THE RHEUMATIC DISEASES SYNOVIAL-MEMBRANE CELLULARITY AND VASCULARITY , pp.511-515 [Details]
                       

Abstract

Minnock, P,McKee, G,Bresnihan, B,FitzGerald, O,Veale, D (2012) Fatigue in patients with rheumatoid arthritis: examination of contributory factors post tumor necrosing factor inhibitor treatment. Abstract [Details]
French, H,Cusack, T,Brennan, A,Fitzpatrick, M,Caffrey, A,Gilsenan, C,Cuddy, V,White, B,Kane, D,O'Connell, P,FitzGerald, O,McCarthy, GM (2011) THE EFFECTIVENESS OF EXERCISE THERAPY WITH AND WITHOUT MANUAL THERAPY FOR HIP OSTEOARTHRITIS: A MULTICENTRE RANDOMISED CONTROLLED TRIAL. Abstract [Details]
FitzGerald, O,Helliwell, P,Mumtaz, A,Coates, L,Pedersen, R,Molta, C (2011) Application of composite disease activity scores in psoriatic arthritis to the PRESTA study. Abstract [Details]
Kirkham, B,Fitzgerald, O,Robertson, D,Estojak, J,Foehl, J,Molta, C,Freundlich, B (2010) INFLUENCE OF BASELINE INFLAMMATION AND OLIGOARTHRITIS VS POLYARTHRITIS ON PSORIASIS RESPONSE TO ETANERCEPT THERAPY IN SUBJECTS WITH BOTH PSORIASIS AND PSORIATIC ARTHRITIS. Abstract [Details]
McCormack, K,Fitzgerald, D,Fitzgerald, O,Caulfield, B,O'Huiginn, B,Smyth, B (2009) A COMPARISON OF A COMPUTER GAME-BASED EXERCISE SYSTEM WITH CONVENTIONAL APPROACHES OF EXERCISE THERAPY IN RHEUMATOLOGY PATIENTS. Abstract [Details]
Winchester, R,Minevich, G,Kane, D,Bresnihan, B,Greenberg, D,FitzGerald, O (2008) Heterogeneity of the psoriasis phenotype revealed by HLA class I haplotype associations in psoriatic arthritis and psoriasis. Abstract [DOI] [Details]
Brulhart, L,Ng, CT,Codd, MB,Walsh, CAE,Pontifex, EK,Lynch, B,Grier, A,Molloy, M,O'Flynn, E,Bresnihan, B,FitzGerald, O,Veale, DJ (2007) Co-medication with methotrexate is not associated with remission in psoriatic arthritis patients on TNFI inhibitors treatment. Abstract [Details]
O'Rourke, M,FitzGerald, O,Bresnihan, B,Veale, D (2007) Psoriatic arthritis: Patient knowledge and its relationship to quality of life. Abstract [Details]
McInnes, LB,Kane, D,Gracie, JA,Gogarty, M,Bresnihan, B,FitzGerald, O (2007) Novel innate response cytokines in psoriatic arthritis. Abstract [Details]
Connolly, M,McCormick, J,Mullan, R,Fitzgerald, O,Bresnihan, B,Veale, D,Fearon, U (2007) A-SAA upregulates chemokine expression, MMP production and GAG release in inflammatory arthritis. Abstract [Details]
Walsh, CAE,FitzGerald, O,Veale, DJ,Golden-Mason, L,Bresnihan, B,Fearon, U (2007) Expansion of synovial fluid CD56 bright NKT cells in inflammatory arthritis associated with increased cytotoxicity and inflammatory cytokine production. Abstract [Details]
Kennedy, A,Sweeney, C,Walshe, T,Cahill, PA,Bresnihan, B,Fitzgerald, O,Fearon, U,Veale, DJ (2007) Regulation of VEGF and angiopoietins in inflammatory arthritis. Abstract [Details]
Gogarty, M,Murphy, EP,Fearon, U,Veale, DJ,Bresnihan, B,FitzGerald, O (2007) Abundant placenta growth factor (PlGF) expression in the inflammatory joint. Abstract [Details]
Gogarty, M,Murphy, EP,Fearon, U,Veale, DJ,Bresnihan, B,FitzGerald, O (2007) Placenta growth factor (PLGF) expression in inflammatory arthritis. Abstract [Details]
Fitzpatrick, M,FitzGerald, O,Staines, A,Hurley, DA (2006) Quality of life and exercise compliance in patients with ankylosing spondylitis: a cross-sectional survey. Abstract [Details]
Mullan, RH,Fearon, U,Mathews, C,Lobanok, T,King, L,FitzGerald, O,Bresnihan, B,Poole, R,Veale, DJ (2006) Serum amyloids a (A-SAA) correlates with joint damage in vivo and induces cartilage matrix degradation in vitro. Abstract [Details]
Pontifex, E,Gogarty, M,Murphy, E,Bresnihan, B,Veale, D,FitzGerald, O (2006) JunB expression in psoriatic arthritis synovium and skin pre- and post-treatment with etanercept. Abstract [Details]
O'Kane, M,Kirby, B,Fitzgerald, O,Mcevoy, A,Murphy, EP (2006) Altered expression of corticotropin-releasing hormone, corticotropin-releasing hormone receptor and NURR1 in psoriasis. Abstract [Details]
O'Kane, M,Kirby, B,FitzGerald, O,McEvoy, A,Murphy, E (2006) Corticotropin-releasing hormone, corticotropin-releasing hormone receptor and NURR1 are increased in psoriasis lesional skin. Abstract [Details]
O'Kane, M,Murphy, E,Fitzgerald, O,Kirby, B (2006) Corticotropin-releasing hormone (CRH), CRH receptor (CRH-R) and NURR1 are increased in psoriasis, further evidence of a brain-skin axis?. Abstract [Details]
Fitzpatrick M, Fitzgerald O, Staines A, Hurley DA; (2006) Exercise Activity in Patients with Ankylosing Spondylitis: A Cross-Sectional Survey. Abstract [Details]
Mullan, RH,Lobanok, T,Walsh, C,King, L,FitzGerald, O,Bresnihan, B,Fearon, U,Poole, R,Veale, DJ (2005) The value of serum type II collagen epitope measurement in assessing early clinical response to treatment with anti-tumour necrosis factor alpha therapy in rheumatoid arthritis. Abstract [DOI] [Details]
Gogarty, M,Murphy, E,Veale, D,Bresnihan, B,Fitzgerald, O (2005) Alternative splicing of the VEGFR-1 (flt-1) and its ligands in human inflammatory arthritis. Abstract [Details]
Ralph, JA,McEvoy, AN,Kane, D,Bresnihan, B,FitzGerald, O,Murphy, EP (2005) Modulation of orphan receptor NURR1 expression by methotrexate in human inflammatory joint disease involves adenosine receptor mediated responses. Abstract [Details]
Ralph, JA,McEvoy, AN,Bresnihan, B,FitzGerald, O,Murphy, EP (2004) Inhibitory effects of low-dose methotrexate on expression of the orphan receptor NURR1 are mediated through the adenosine type A2 receptor. Abstract [Details]
O'Kane, M,Kirby, B,Fitzgerald, O,Veale, D,Markham, T,Murphy, E (2004) Corticotropin-releasing hormone - a possible role in psoriasis. Abstract [Details]
Mullan, RH,Golden-Mason, L,Markham, T,O'Hara, R,FitzGerald, O,Bresnihan, B,Veale, DJ,Fearon, U (2004) Acute-phase serum amyloid a stimulates angiogenesis, leukocyte recruitment and matrix degradation in RA via NF kappa B and MAPK-dependent pathways. Abstract [Details]
Mullan, RH,Lobanok, T,Walsh, E,King, L,FitzGerald, O,Bresnihan, B,Fearon, U,Poole, R,Veale, DJ (2004) The value of serum type II collagen epitope measurement in assessing early clinical response to treatment with anti-TNF-alpha therapy in rheumatoid arthritis. Abstract [Details]
Mullan, RH,Mason, LG,Markham, T,O'Hara, R,FitzGerald, O,Bresnihan, B,Veale, DJ,Fearon, U (2003) A novel role for serum Amyloid-A (A-SAA) in angiogenesis and adhesion molecule expression through an NF kappa B-dependent signal transduction pathway. Abstract [Details]
Real, KJ,Kane, D,Duffy, T,FitzGerald, O,Masterson, BF (2003) The contact system in inflammatory arthritis. Abstract [Details]
Ralph, JA,Bresnihan, B,FitzGerald, O,Murphy, EP (2003) Methotrexate inhibits the production of the transcription factor NURR1 in human inflammatory joint disease. Abstract [Details]
Duffy, TN,Fearon, U,Godson, C,Brady, H,Bresnihan, B,Veale, D,FitzGerald, O (2003) Profibrotic mRNA is preferentially expressed in bone forming arthritis. Abstract [Details]
Youssef, PP,Breedveld, FC,Bresnihan, B,Cassidy, N,Cunnane, G,Emery, P,FitzGerald, O,Kane, D,Kraan, M,Lindblad, S,Reece, R,Veale, D,Tak, PP (1997) Quantitative microscopic analysis of inflammation in rheumatoid arthritis synovial membrane samples selected at arthroscopy compared with samples taken blindly by needle biopsy. Abstract [Details]
Youssef, PP,Roth, J,Costello, P,Cassidy, N,Cunnane, G,FitzGerald, O,Bresnihan, B (1997) Differential expression of MRP8, MRP14 and the MRP8/14 heterodimer at the cartilage-pannus junction compared with other sites in rheumatoid arthritis (RA) synovium. Abstract [Details]
Cunnane, G,FitzGerald, O,Hummel, KM,Youssef, P,Kane, D,Gay, RE,Gay, S,Bresnihan, B (1997) Detection of collagenase, cathepsin B and cathepsin L messenger RNA expression in synovial tissues of patients with early inflammatory arthritis. Abstract [Details]
Yuossef, PP,Smeets, TJ,Eresnihan, B,Cunnane, G,FitzGerald, O,Breedveld, F,Kraan, M,Tak, PP (1997) Microscope measurement of inflammation in rheumatoid arthritis synovial membrane: A comparison of two methods. Abstract [Details]
Cunnane, G,Summers, C,Taylor, D,Cawston, T,Bresnihan, B,FitzGerald, O (1996) Elevated serum and synovial fluid levels of collagenase, stromelysin and tissue inhibitor of metalloproteinases (TIMP-1) in early inflammatory arthritis. Abstract [Details]
MULHERIN, D,FITZGERALD, O,BRESNIHAN, B (1995) DISTRIBUTION OF MACROPHAGE POPULATIONS IN RHEUMATOID SYNOVIUM - EVIDENCE FOR MACROPHAGE MATURATION IN LINING LAYER. Abstract [Details]
MARTIN, K,TALUKDER, R,MULHERIN, D,FITZGERALD, O,AXFORD, JS (1995) IMMUNOGLOBULIN-G ASSOCIATED OLIGOSACCHARIDES IN ANKYLOSING-SPONDYLITIS, PSORIATIC AND RHEUMATOID-ARTHRITIS - SIMILARITIES AND DIFFERENCES. Abstract [Details]
MULHERIN, D,FITZGERALD, O,BRESNIHAN, B (1995) MECHANISMS OF ARTICULAR DESTRUCTION IN THE FEET AND HANDS MAY DIFFER. Abstract [Details]
MULHERIN, D,FITZGERALD, O,BRESNIHAN, B (1993) RADIOLOGIC PROGRESSION IN RHEUMATOID-ARTHRITIS OVER 6-YEARS CORRELATES WITH MACROPHAGE NUMBERS IN THE SYNOVIUM. Abstract [Details]
MULHERIN, D,HEFFERNAN, M,BRESNIHAN, B,FITZGERALD, O (1993) SOLUBLE E-SELECTIN LEVELS IN SERUM AND SYNOVIAL-FLUID FROM PATIENTS WITH PSORIATIC AND OTHER INFLAMMATORY ARTHROPATHIES. Abstract [Details]
MULHERIN, D,FITZGERALD, O,BRESNIHAN, B (1992) LYMPHEDEMA OF THE UPPER LIMB IN PSORIATIC-ARTHRITIS. Abstract [Details]
       

Reviews

Ash, Z,Gaujoux-Viala, C,Gossec, L,Hensor, EMA,FitzGerald, O,Winthrop, K,van der Heijde, D,Emery, P,Smolen, JS,Marzo-Ortega, H (2012) A systematic literature review of drug therapies for the treatment of psoriatic arthritis: current evidence and meta-analysis informing the EULAR recommendations for the management of psoriatic arthritis. Reviews [DOI] [Details]
Gossec, L,Smolen, JS,Gaujoux-Viala, C,Ash, Z,Marzo-Ortega, H,van der Heijde, D,FitzGerald, O,Aletaha, D,Balint, P,Boumpas, D,Braun, J,Breedveld, FC,Burmester, G,Canete, JD,de Wit, M,Dagfinrud, H,de Vlam, K,Dougados, M,Helliwell, P,Kavanaugh, A,Kvien, TK,Landewe, R,Luger, T,Maccarone, M,McGonagle, D,McHugh, N,McInnes, IB,Ritchlin, C,Sieper, J,Tak, PP,Valesini, G,Vencovsky, J,Winthrop, KL,Zink, A,Emery, P (2012) European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies. Reviews [DOI] [Details]
                                                   

Letters

Bowes, J,Ho, P,Flynn, E,Salah, S,McHugh, N,FitzGerald, O,Packham, J,Morgan, AW,Helliwell, PS,Bruce, IN,Barton, A (2012) Investigation of IL1, VEGF, PPARG and MEFV genes in psoriatic arthritis susceptibility. Letters [DOI] [Details]
Kane, D,Fitzgerald, O (1998) Ultrasound guided injection of plantar fasciitis - Reply. Letters [Details]
Mulherin, D,FitzGerald, O,Bresnihan, B (1997) Clinical improvement and radiological deterioration in rheumatoid arthritis - Reply. Letters [Details]
Mulherin, D,FitzGerald, O,Bresnihan, B,ODonoghue, D,McCarthy, D (1997) Hypochromic red cells as an indicator of iron deficiency - Reply. Letters [Details]
MULHERIN, D,BRESNIHAN, B,FITZGERALD, O (1995) DIGITAL DENERVATION ASSOCIATED WITH ABSENCE OF NAIL AND DISTAL INTERPHALANGEAL JOINT INVOLVEMENT IN PSORIATIC-ARTHRITIS. Letters [Details]
CUNNANE, G,OBYRNE, AM,HEGARTY, J,FITZGERALD, O (1994) HEPATIC HYPERTROPHIC OSTEOARTHROPATHY AND LIVER-TRANSPLANTATION. Letters [Details]

Research

Research Interests

Main interests relate to inflammatory arthritis, in particular developing outcome measures and biomarkers of treatment response. The following are current projects: 
(1) Biomarkers of disease diagnosis in Psoriatic Arthritis. Co Pi: Prof Steve Pennington

(2) Biomarkers of treatment response in Psoriatic Arthritis. Co Pi: Prof Steve Pennington

(3) Genetics of Psoriasis and Psoriatic Arthritis. Well-established collaboration with Professor Robert Winchester at Columbia University, New York

(4) Coronary CT scanning in inflammatory arthritis

 

FUNDING AGENCIES: 
HRB RCQPS Grant 
EUFP7 Programme Grant (MIAMI) 

HRB project grant (PAPRICA)
Abbvie Grant 
BMS Grant

 

UCD Medicine Research Group: Arthritis and Rheumatic Disease

Research Projects

Sponsor : Health Research Board (HRB)
Title : PAPRICA: Protein Biomarker Assays for Psoriatic Arthritis - Clinical Evaluation and Validation of Multiplexed Panels for Diagnosis and Prognosis
Start Date / End Date : 01-MAR-16 / 01-APR-18
Sponsor : EC Framework (FP7)
Title : MIAMI - Monitoring innate immunity in arthritis and mucosal inflammation
Start Date / End Date : 01-FEB-13 / 31-JAN-16
Sponsor : Abbott Laboratories Ireland Ltd.
Title : Development of Composite Disease Activity Index in Psoriatic Arthritis
Start Date / End Date : 01-JUL-08 / 30-JUN-10

Recent Postgraduates

Muhammad Haroon Doctor of Philosophy (PhD)

Musaab Elmamoun Medicine (MD)

Angela McArdle (PhD)

Matthew Doyle (PhD)

Current Postgraduate Students

Musaab Elmamoun, Medicine (MD)   -   Thesis Supervisor

Collaborators

Internal Collaborators

Ms Phil Gallagher, Research Stucy Coordinator

Dr Agnes Szentepetery, Research Fellow

Dr Ali Said Mohammed, SpR

Dr Flora Farkas (Clinical Observer)

Dr Natsumi Ikumi (Clinical Fellow)

Ms Annie Baker (Clinical Trials Coordinator)
Prof. Brian Kirby, Dept Dermatology SVHG
Prof Steve Pennington, Proteomics UCD

Dr Barry O¿Shea (TCD)

Prof J Dodd (SVUH)