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Researchers at UCD

Denise Sadlier

Senior Clinical Lecturer

School Of Medicine & Medical Science
Mater Hospital
Eccles Street
Dublin 7

Tel: +353 1 7164568
Email: denise.sadlier@ucd.ie

Professional

               

Education

Year 1998 Institution:
Qualification: MRCPI Subject:
Year 1996 Institution: University College Dublin
Qualification: MB, BCh, BAO Subject:
         

Publications

 

Book Chapters

Ryan A, Sadlier, DM and Godson C Animal models of glomerulonphritis. In Fundamentals of Inflammation, Serhan, Ward and Gilroy (Eds.) Cambridge University Press, In press 2009; (2010) 'Animal models of glomerulonphritis' In: Fundamentals of Inflammation. NY: Cambridge University Press. [Details]
Sadlier DM, O'Meara YM; (2009) 'Recurrent and De Novo Renal Diseases after Kidney Transplantation' In: Himmelfarb J, Sayegh MH (eds). Chronic Kidney Disease, Dialysis, and Transplantation: A Companion to Brenner and Rectors¿ The Kidney. Philadelphia: Elsevier. [Details]
Sadlier D, O¿Meara Y M. ; (2005) 'Recurrent and de novo renal disease in kidney transplantation' In: Pereira BJ and Sayegh MH., Blake P. W.B. Saunders Co. Philadelphia, pp708-721, 2005 (eds). Chronic Kidney Disease, Dialysis, and Transplantation: A Companion to Brenner and Rectors¿ The Kidney. Philadelphia: W.B. Saunders Co. [Details]
 

Peer Reviewed Journals

Bennett G, Sadlier D, Doran PP, Macmathuna P, Murray DW; (2011) 'A functional and transcriptomic analysis of NET1 bioactivity in gastric cancer'. BMC Cancer, 11 . [DOI] [Details]
Rooney, B,O'Donovan, H,Gaffney, A,Browne, M,Faherty, N,Curran, SP,Sadlier, D,Godson, C,Brazil, DP,Crean, J; (2011) 'CTGF/CCN2 activates canonical Wnt signalling in mesangial cells through LRP6: Implications for the pathogenesis of diabetic nephropathy'. FEBS letters, 585 :531-538. [DOI] [Details]
Rooney B, O'Donovan, H., Browne, M., Gaffney, A., Curran, SP., Brazil, DP. Godson, C., Sadlier, D and Crean, JK. ; (2010) 'CTGF/CCN2 activates canonical Wnt signaling in mesangial cells through LRP6; implications for the pathogenesis of diabetic nephropathy'. European journal of biochemistry / FEBS, . [Details]
McKnight, AJ,Patterson, CC,Sandholm, N,Kilner, J,Buckham, TA,Parkkonen, M,Forsblom, C,Sadlier, DM,Groop, PH,Maxwell, AP,Warren 3 UK Gokind Study Grp; (2010) 'Genetic Polymorphisms in Nitric Oxide Synthase 3 Gene and Implications for Kidney Disease: A Meta-Analysis'. American Journal of Nephrology, 32 :476-481. [DOI] [Details]
Currie, D,McKnight, AJ,Patterson, CC,Sadlier, DM,Maxwell, AP,UK Warren 3 GoKinD Study Grp; (2010) 'Investigation of ACE, ACE2 and AGTR1 genes for association with nephropathy in Type 1 diabetes mellitus'. Diabetic Medicine, 27 :1188-1194. [DOI] [Details]
Devitt, E,Lawless, MW,Sadlier, D,Browne, JA,Walsh, C,Crowe, J; (2010) 'Early viral and peripheral blood mononuclear cell responses to pegylated interferon and ribavirin treatment: the first 24 h'. European Journal of Gastroenterology & Hepatology, 22 :1211-1220. [DOI] [Details]
Martin, RJL,McKnight, AJ,Patterson, CC,Sadlier, DM,Maxwell, AP,Warren 3 UK GoKinD Study Grp; (2010) 'A rare haplotype of the vitamin D receptor gene is protective against diabetic nephropathy'. Nephrology Dialysis Transplantation, 25 :497-503. [DOI] [Details]
McKnight, AJ,Pettigrew, KA,Patterson, CC,Kilner, J,Sadlier, DM,Maxwell, AP,Warren 3 UK GoKinD Study Grp; (2010) 'Investigation of the association of BMP gene variants with nephropathy in Type 1 diabetes mellitus'. Diabetic Medicine, 27 :624-630. [DOI] [Details]
McKnight, AJ,Patterson, CC,Pettigrew, KA,Savage, DA,Kilner, J,Murphy, M,Sadlier, D,Maxwell, AP,Warren 3 UK Genetics Kidneys Diab; (2010) 'A GREM1 Gene Variant Associates with Diabetic Nephropathy'. J AM SOC NEPHROL, 21 :773-781. [DOI] [Details]
Pettigrew, KA,McKnight, AJ,Patterson, CC,Kilner, J,Sadlier, DM,Maxwell, AP; (2010) 'Resequencing of the CCL5 and CCR5 genes and investigation of variants for association with diabetic nephropathy'. Gene, 55 :248-251. [DOI] [Details]
Fitzgerald DJ, Doherty GA, Byrne SM, Austin SC, Scully GM, Sadlier DM, Neilan TG, Kay EW, Murray FE, ; (2009) 'Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer'. Cancer, 101 (3):483-491. [DOI] [Details]
Egido J, Gallego-Delgado J, Connolly SB, Lázaro A, Sadlier D, Kieran NE, Sugrue DD, Doran P, Brady HR, Osende J, ; (2009) 'Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies'. Hypertension research : official journal of the Japanese Society of Hypertension, 32 (5):347-357. [DOI] [Details]
Egido J, Gallego-Delgado J, Connolly SB, Lázaro A, Sadlier D, Kieran NE, Sugrue DD, Doran P, Brady HR, Osende J, ; (2009) 'Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies'. Hypertension research : official journal of the Japanese Society of Hypertension, 5 (NA):347-357. [DOI] [Details]
McKnight, AJ,Maxwell, AP,Fogarty, DG,Sadlier, D,Savage, DA,Warren 3 UK GoKinD Study Grp; (2009) 'Genetic analysis of coronary artery disease single-nucleotide polymorphisms in diabetic nephropathy'. Nephrology Dialysis Transplantation, 24 :2473-2476. [DOI] [Details]
Gallego-Delgado, J,Connolly, SB,Lazaro, A,Sadlier, D,Kieran, NE,Sugrue, DD,Doran, P,Brady, HR,Osende, J,Egido, J; (2009) 'Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies'. Hypertension research : official journal of the Japanese Society of Hypertension, 32 :347-357. [DOI] [Details]
McKnight, AJ,Woodman, AM,Parkkonen, M,Patterson, CC,Savage, DA,Forsblom, C,Pettigrew, KA,Sadlier, D,Groop, PH,Maxwell, AP,Warren 3 UK GoKinD Study Grp; (2009) 'Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus'. Diabetologia, 52 :844-849. [DOI] [Details]
Brennan, EP,Ehrich, M,Brazil, DP,Crean, JK,Murphy, M,Sadlier, DM,Martin, F,Godson, C,McKnight, AJ,van den Boom, D,Maxwell, AP,Savage, DA; (2009) 'Comparative analysis of dna methylation profiles in peripheral blood leukocytes versus lymphoblastoid cell lines'. Gene, 4 :159-164. [Details]
Doherty, GA,Byrne, SM,Austin, SC,Scully, GM,Sadlier, DM,Neilan, TG,Kay, EW,Murray, FE,Fitzgerald, DJ; (2009) 'Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer'. Cancer, 101 :483-491. [DOI] [Details]
Godson C, Murphy M, Crean J, Brazil DP, Sadlier D, Martin F, ; (2008) 'Regulation and consequences of differential gene expression in diabetic kidney disease'. Biochemical Society Transactions, Pt 5 (NA):941-945. [DOI] [Details]
Savage, DA,Patterson, CC,Deloukas, P,Whittaker, P,McKnight, AJ,Morrison, J,Boulton, AJ,Demaine, AG,Marshall, SM,Millward, BA,Thomas, SM,Viberti, GC,Walker, JD,Sadlier, D,Maxwell, AP,Bain, SC; (2008) 'Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy'. Diabetologia, 51 :1998-2002. [DOI] [Details]
Currie, D,Maxwell, AP,Sadlier, D,McKnight, AJ,Warren 3 UK GoKinD Study Grp; (2008) 'Investigation of Adducin 2 (beta) DNA polymorphisms in genetic predisposition to diabetic nephropathy in Type 1 diabetes'. Diabetic Medicine, 25 :1001-1005. [DOI] [Details]
Keating, DTK,Malizia, AP,Sadlier, D,Hurson, C,Wood, AE,McCarthy, J,Nolke, L,Egan, JJ,Doran, PP; (2008) 'LUNG TISSUE STORAGE: OPTIMIZING CONDITIONS FOR FUTURE USE IN MOLECULAR RESEARCH'. Experimental Lung Research, 34 (NA):455-466. [DOI] [Details]
Murphy M, Crean JK, Brazil DP, Sadlier D, Martin F and Godson C ; (2008) 'Regulation and consequences of differential gene expression in diabetic kidney disease'. Biochem J, 36 :941-945. [Details]
Godson C, Murphy M, Crean J, Brazil DP, Sadlier D, Martin F, ; (2008) 'Regulation and consequences of differential gene expression in diabetic kidney disease'. Biochemical Society Transactions, 36 (Pt 5):941-945. [DOI] [Details]
Hurson, C. J.,Butler, J. S.,Keating, D. T.,Murray, D. W.,Sadlier, D. M.,O'Byrne, J. M.,Doran, P. P.; (2007) 'Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis'. BMC Musculoskelet Disord, 8 . [Details]
Hurson, CJ, Butler, JS, Keating, DT, Murray, DW, Sadlier, DM, OByrne, JM, Doran, PP, ; (2007) 'Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis'. BMC MUSCULOSKEL DIS, 8 . [Details]
McKnight, AJ,Savage, DA,Patterson, CC,Sadlier, D,Maxwell, AP; (2007) 'Resequencing of genes for transforming growth factor beta 1 (TGFB1) type 1 and 2 receptors (TGFBR1, TGFBR2), and association analysis of variants with diabetic nephropathy'. Gene, 8 . [DOI] [Details]
Hurson, C. J.Hurson, C. J.,Butler, J. S.Butler, J. S.,Keating, D. T.Keating, D. T.,Murray, D. W.Murray, D. W.,Sadlier, D. M.Sadlier, D. M.,O'Byrne, J. M.O'Byrne, J. M.,Doran, P. P.Doran, P. P.; (2007) 'Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis'. Bmc Musculoskeletal DisordersBmc Musculoskeletal DisordersBmc Musculoskeletal Disorders, 8 . Available Online [Details]
Hurson, CJ,Butler, JS,Keating, DT,Murray, DW,Sadlier, DM,O'Byrne, JM,Doran, PP; (2007) 'Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis'. BMC MUSCULOSKEL DIS, 8 . [DOI] [Details]
Butler, J. S.Butler, J. S.,Hurson, C.Hurson, C.,Murray, D.Murray, D.,Sadlier, D.Sadlier, D.,O'Byrne, J. M.O'Byrne, J. M.,Doran, P. P.Doran, P. P.; (2006) 'Altered developmental pathways as novel drivers of osteoporosis in primary human osteoblasts'. Osteoporosis InternationalOsteoporosis InternationalOsteoporosis International, 17 . Available Online [Details]
Keating, DT; Sadlier, DM; Patricelli, A; Smith, SM; Walls, D; Egan, JJ; Doran, PP; ; (2006) 'Microarray identifies ADAM family members as key responders to TGF-beta 1 in alveolar epithelial cells'. Respiratory Research, 7 (NA). [Details]
Keating, DT; Sadlier, DM; Patricelli, A; Smith, SM; Walls, D; Egan, JJ; Doran, PP; ; (2006) 'Microarray identifies ADAM family members as key responders to TGF-beta 1 in alveolar epithelial cells'. Respiratory Research, 7 (NA). [Details]
Keating, DT,Sadlier, DM,Patricelli, A,Smith, SM,Walls, D,Egan, JJ,Doran, PP; (2006) 'Microarray identifies ADAM family members as key responders to TGF-beta 1 in alveolar epithelial cells'. Respiratory Research, 7 . [DOI] [Details]
Keating DT, Sadlier D, Linehan R, Patricelli A, Smith S, Walls D, Egan JJ, Doran P. ; (2006) 'Microarray gene profiling identifies ADAM family members as key mediators of pulmonary fibrosis'. Respiratory Research, 7 . [Details]
Brady HR, Dolan V, Murphy M, Sadlier D, Lappin D, Doran P, Godson C, Martin F, O'Meara Y, Schmid H, Henger A, Kretzler M, Droguett A, Mezzano S, ; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. American journal of kidney diseases : the official journal of the National Kidney Foundation, 6 (NA):1034-1039. [Details]
Johnson RJ, Sadlier DM, Ouyang X, McMahon B, Mu W, Ohashi R, Rodgers K, Murray D, Nakagawa T, Godson C, Doran P, Brady HR, ; (2005) 'Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis'. Kidney International, 68 (6):2542-2561. [DOI] [Details]
Sadlier, D. M.Sadlier, D. M.,Ouyang, X.Ouyang, X.,McMahon, B.McMahon, B.,Mu, W.Mu, W.,Ohashi, R.Ohashi, R.,Rodgers, K.Rodgers, K.,Murray, D.Murray, D.,Nakagawa, T.Nakagawa, T.,Godson, C.Godson, C.,Doran, P.Doran, P.,Brady, H. R.Brady, H. R.,Johnson, R. J.Johnson, R. J.; (2005) 'Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis'. Kidney InternationalKidney InternationalKidney International, 68 (66):2542-25612542. Available Online [Details]
Brady HR, Dolan V, Murphy M, Sadlier D, Lappin D, Doran P, Godson C, Martin F, O'Meara Y, Schmid H, Henger A, Kretzler M, Droguett A, Mezzano S, ; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. American journal of kidney diseases : the official journal of the National Kidney Foundation, 45 (6):1034-1039. [Details]
Brady HR, Dolan V, Murphy M, Sadlier D, Lappin D, Doran P, Godson C, Martin F, O'Meara Y, Schmid H, Henger A, Kretzler M, Droguett A, Mezzano S, ; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. American journal of kidney diseases : the official journal of the National Kidney Foundation, 45 (6):1034-1039. [Details]
Sadlier, D. M.,Ouyang, X.,McMahon, B.,Mu, W.,Ohashi, R.,Rodgers, K.,Murray, D.,Nakagawa, T.,Godson, C.,Doran, P.,Brady, H. R.,Johnson, R. J.; (2005) 'Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis'. Kidney Int, 68 (6):2542-61. [Details]
Dolan, V.,Murphy, M.,Sadlier, D.,Lappin, D.,Doran, P.,Godson, C.,Martin, F.,O'Meara, Y.,Schmid, H.,Henger, A.,Kretzler, M.,Droguett, A.,Mezzano, S.,Brady, H. R.; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. Am J Kidney Dis, 45 (6):1034-9. [Details]
Rodgers, K; McMahon, B; Mitchell, D; Sadlier, D; Godson, C; ; (2005) 'Lipoxin A(4) modifies platelet-derived growth factor-induced profibrotic gene expression in human renal mesangial cells'. American Journal of Pathology, 167 (3):683-694. [Details]
Dolan, V; Murphy, M; Sadlier, D; Lappin, D; Doran, P; Godson, C; Martin, F; O'Meara, Y; Schmid, H; Henger, A; Kretzler, M; Droguett, A; Mezzano, S; Brady, HR; ; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. American Journal of Kidney Diseases, 45 (6):1034-1039. [Details]
Yasuda, Y; Schmid, H; Boucherot, A; Eichinger, F; Brunner, B; Sadlier, DM; Henger, A; Nitsche, A; Bleich, M; Cohen, CD; Doran, P; Brady, HR; Groene, HJ; Schloendorff, D; Nelson, PJ; Kretzler, M; ; (2005) 'Genome-wide transcriptomic analysis identifies gene expression signature of NF-kappa B pathway activation in progressive human diabetic nephropathy'. Nephrology Dialysis Transplantation, 20 (NA):371-371. [Details]
Dolan, V; Murphy, M; Sadlier, D; Lappin, D; Doran, P; Godson, C; Martin, F; O'Meara, Y; Schmid, H; Henger, A; Kretzler, M; Droguett, A; Mezzano, S; Brady, HR; ; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. American Journal of Kidney Diseases, 45 (6):1034-1039. [Details]
Rodgers, K,McMahon, B,Mitchell, D,Sadlier, D,Godson, C; (2005) 'Lipoxin A(4) modifies platelet-derived growth factor-induced profibrotic gene expression in human renal mesangial cells'. The Journal of pathology, 167 :683-694. [Details]
Sadlier, DM, Ouyang, X, McMahon, B, Mu, W, Ohashi, R, Rodgers, K, Murray, D, Nakagawa, T, Godson, C, Doran, P, Brady, HR, Johnson, RJ, ; (2005) 'Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis'. Kidney International, 68 (6):2542-2561. [Details]
Dolan, V,Murphy, M,Sadlier, D,Lappin, D,Doran, P,Godson, C,Martin, F,O'Meara, Y,Schmid, H,Henger, A,Kretzler, M,Droguett, A,Mezzano, S,Brady, HR; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. American journal of kidney diseases : the official journal of the National Kidney Foundation, 45 :1034-1039. [DOI] [Details]
Sadlier, DM; Ouyang, X; McMahon, B; Mu, W; Ohashi, R; Rodgers, K; Murray, D; Nakagawa, T; Godson, C; Doran, P; Brady, HR; Johnson, RJ; ; (2005) 'Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis'. Kidney International, 68 (6):2542-2561. [Details]
Dolan, V; Murphy, M; Sadlier, D; Lappin, D; Doran, P; Godson, C; Martin, F; O'Meara, Y; Schmid, H; Henger, A; Kretzler, M; Droguett, A; Mezzano, S; Brady, HR; ; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. American Journal of Kidney Diseases, 45 (6):1034-1039. [Details]
Sadlier, DM; Ouyang, X; McMahon, B; Mu, W; Ohashi, R; Rodgers, K; Murray, D; Nakagawa, T; Godson, C; Doran, P; Brady, HR; Johnson, RJ; ; (2005) 'Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis'. Kidney International, 68 (6):2542-2561. [Details]
Dolan, V; Murphy, M; Sadlier, D; Lappin, D; Doran, P; Godson, C; Martin, F; O'Meara, Y; Schmid, H; Henger, A; Kretzler, M; Droguett, A; Mezzano, S; Brady, HR; ; (2005) 'Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy'. American Journal of Kidney Diseases, 45 (6):1034-1039. [Details]
Sadlier, D. M.,Connolly, S. B.,Kieran, N. E.,Roxburgh, S.,Brazil, D. P.,Kairaitis, L.,Wang, Y.,Harris, D. C.,Doran, P.,Brady, H. R.; (2004) 'Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy'. J Biol Chem, 279 (28):29670-80. [Details]
Sadlier, DM; Connolly, SB; Kieran, NE; Roxburgh, S; Brazil, DP; Kairaitis, L; Wang, Y; Harris, DCH; Doran, P; Brady, HR; ; (2004) 'Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy'. Journal of Biological Chemistry, 279 (28):29670-29680. [Details]
Brady HR, Sadlier DM, Connolly SB, Kieran NE, Roxburgh S, Brazil DP, Kairaitis L, Wang Y, Harris DC, Doran P, ; (2004) 'Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy'. Journal of Biological Chemistry, 279 (28):29670-29680. [DOI] [Details]
Sadlier, DM; Connolly, SB; Kieran, NE; Roxburgh, S; Brazil, DP; Kairaitis, L; Wang, Y; Harris, DCH; Doran, P; Brady, HR; ; (2004) 'Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy'. Journal of Biological Chemistry, 279 (28):29670-29680. [Details]
Keating, DT; Sadlier, D; Hurson, C; Doran, P; Egan, JJ; ; (2004) 'Oligonucleotide microarray analysis reveals coordinated expression of extracellular matrix associated genes in pulmonary fibrosis in vitro'. Thorax, 59 (1):42-42. [Details]
Sadlier, DM; Connolly, SB; Kieran, NE; Roxburgh, S; Brazil, DP; Kairaitis, L; Wang, Y; Harris, DCH; Doran, P; Brady, HR; ; (2004) 'Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy'. Journal of Biological Chemistry, 279 (28):29670-29680. [Details]
Connolly, S. B.,Sadlier, D.,Kieran, N. E.,Doran, P.,Brady, H. R.; (2003) 'Transcriptome profiling and the pathogenesis of diabetic complications'. J Am Soc Nephrol, 14 (8 Suppl 3):S279-83. [Details]
Sadlier, DM; Brazil, D; Doran, P; Brady, HR; ; (2003) 'Microarray and bioinformatic analysis identified common patterns of matrix gene expression in glomerular injury dependent and independent models of tubulo-interstitial fibrosis in vivo'. Journal of the American Society of Nephrology, 14 (NA):366-366. [Details]
Connolly, SB; Sadlier, D; Kieran, NE; Doran, P; Brady, HR; ; (2003) 'Transcriptome profiling and the pathogenesis of diabetic complications'. Journal of the American Society of Nephrology, 14 (NA):279-283. [Details]
Sadlier, DM; Brazil, D; Doran, P; Brady, HR; ; (2003) 'Microarray and bioinformatic analysis identified common patterns of matrix gene expression in glomerular injury dependent and independent models of tubulo-interstitial fibrosis in vivo'. Journal of the American Society of Nephrology, 14 (NA):366-366. [Details]
Sadlier, DM; Frawley, A; Doran, P; Brady, HR; ; (2003) 'Comparison of bioinformatic techniques for analysis of microarray generated datasets reveals algorithm dependent conclusions regarding quantitative gene expression'. Journal of the American Society of Nephrology, 14 (NA):23-23. [Details]
Sadlier, DM; Brazil, D; Doran, P; Brady, HR; ; (2003) 'Microarray and bioinformatic analysis identified common patterns of matrix gene expression in glomerular injury dependent and independent models of tubulo-interstitial fibrosis in vivo'. Journal of the American Society of Nephrology, 14 (NA):366-366. [Details]
Friel S, Hope A, Kelleher C, Comer S, Sadlier D. ; (2002) 'Impact evaluation of an oral health intervention amongst primary school children in Ireland'. Health Promot Int, 17 (2):119-126. [Details]
 

Conference Publications

Rooney B, Gaffney, A., Godson, C., Sadlier, D and Crean, JK.; (2010) CTGF/CCN2 activates canonical Wnt signaling in mesangial cells through LRP6; implications for the pathogenesis of diabetic nephropathy American Society of Nephrology [Details]
Godson C, Murphy M, Crean J, Brazil DP, Sadlier D, Martin F, ; (2008) Biochemical Society transactions Regulation and consequences of differential gene expression in diabetic kidney disease , pp.941-945 [DOI] [Details]
Lawlor, G., Murray, D, Moss, A., Leyden, J., Sadlier, D., O' Keane, C., Mulligan, AM., Arumuguma, M., Doyle, E., McEntee, G., MacMathuna, P. Doran, P.; (2006) Gastrointestinal Epithelial Cancers ' A Common Gene Expression Profile? The Irish Association for Cancer Research Annual Meeting [Details]
Keating, D.T., Sadlier, D.M., Patricelli, A., Smith, S.M., Walls, D., Egan, J.J Doran, P.P.; (2005) Computational transcriptome annotation; A powerful strategy in respiratory research American Thoracic Society [Details]
Keating, D.T., Sadlier, D.M., Patricelli, A., Smith, S.M., Walls, D., Egan, J.J Doran, P.P.; (2005) Growth factor expression in pulmonary fibrosis; a genome wide view American Thoracic Society [Details]
Keating, D.T., Sadlier, D.M., Patricelli, A., Smith, S.M., Walls, D., Egan, J.J Doran, P.P.; (2005) Analysis of oligonucleotide microarray reveals coordinated expression of extracellular matrix associated genes in an in vitro model of pulmonary fibrosis American Thoracic Society [Details]
Keating, D.T., Sadlier, D., Linehan, R., Patricelli, A., Smith, S.M., Walls , D., Doran, P. Egan, J.J.; (2005) Microarrays reveal co-ordinated expression of ADAMs family of genes in an in vitro model of pulmonary fibrosis European respiratory society [Details]
                                                                                         

Research

Research Interests

Research Projects

Sponsor : University College Dublin Foundation Ltd.
Title : Gremlin in renal fibrosis
Start Date / End Date : 01-SEP-09 / 30-AUG-10