School Of Medicine & Medical Science
Our Lady's Hospital
Tel: +353 1 716
David Barton is Chief Scientist (Director) of the Molecular Genetics Laboratory at the National Centre for Medical Genetics in Dublin, Ireland, and Adjunct Associate Professor at University College Dublin. Having trained in Trinity College Dublin, and The Queen's University of Belfast, he carried out medical genetics research at Yale University and Cambridge University before setting up the NHS molecular genetics diagnostic laboratory in Cambridge. He returned to Dublin to set up his current laboratory at the National Centre for Medical Genetics in 1995.
Dr Barton has been involved in work to monitor and improve the quality of genetic testing for many years, working with UK NEQAS, the OECD and EuroGentest. He currently chairs the European Molecular Genetics Quality Network. He co-ordinated the EU CRMGEN project, developing certified reference materials for genetic testing. In EuroGentest he continues to work on reference materials development and also has responsibility for examining the role and impact of IVD regulation in genetic testing. David Barton has published over 100 papers in peer-reviewed journals on many aspects of the molecular genetics of inherited disorders. Research interests include the genetics of vesicoureteral reflux, male infertility and the development of novel DNA diagnostic devices.
|Kristofferson U, Schmidke J, Cassiman JJ eds. ; (2010) 'The European IVD Directive and Genetic Testing' In: Quality Issues in Clinical Genetic Services. Springer: Springer. [Details]|
Peer Reviewed Journals
|Hawkins M, Boyle J, Wright KE, Elles R, Ramsden SC, O¿Grady A, Sweeney M, Barton DE, Burgess T, Moore M, Burns C, Stacey G, Gray E, Metcalfe P, Hawkins JR; (2010) 'Preparation and validation of the first WHO international genetic reference panel for Fragile X syndrome'. European Journal of Human Genetics, . [DOI] [Details]|
|Mocanu E, Shattock R, Barton D, Rogers M, Conroy R, Sheils O, Collins C, Martin C, Harrison R, O'Leary J.; (2010) 'All azoospermic males should be screened for cystic fibrosis mutations before intracytoplasmic sperm injection'. Fertility and Sterility, . [Details]|
|Castellani C; Macek M; Cassiman J-J; Duff A; Massie J; Ten Kate LP; Barton D; Cutting G; Dallapiccola B; Dequeker E; Girodon E; Grody W; Highsmith EW; Kääriäinen H; Kruip S; Morris M; Pignatti PF; Pypops U; Schwarz M; Soller M; Stuhrman M; Cuppens H; (2010) 'Benchmarks for Cystic Fibrosis Carrier Screening: A European Consensus Document'. Journal of Cystic Fibrosis, . [Details]|
|Sunnotel O, Hiripi L, Lagan K, McDaid JR, De León JM, Miyagawa Y, Crowe H, Kaluskar S, Ward M, Scullion C, Campbell A, Downes CS, Hirst D, Barton D, Mocanu E, Tsujimura A, Cox MB, Robson T, Walsh CP.; (2010) 'Alterations in the steroid hormone receptor co-chaperone FKBPL are associated with male infertility: a case-control study'. Reproductive biology and endocrinology : RB&E, 8 (22). [Details]|
|Barton DE, de Light J, Hehir-Kwa JY, Brady C, Veltman J; (2010) Universal Reference Samples for Diagnostic Copy-Number Variation Analysis The European Society of Human Genetics 2010 [Details]|
|Higgins M, Crowley A, McDevitt T, Cody N, Meany M, de Baroid C, Adams M, Berkeley E, Nolan C, Clarke R, Farrell M, Daly P, Green A, Barton D; (2009) Spectrum and Incidence of BRCA1 and BRCA2 Mutations in the Republic of Ireland ¿ An Audit British Human Genetics Conference 2009 [Details]|
|Sweeney M, Baker L, Graham CA, Barton DE, Lynch SA; (2009) Incidence of Fragile X Syndrome in the Republic of Ireland 12th Annual Scientific Meeting of the Irish Society of Human Genetics, Friday 18th September 2009 [Details]|
Our laboratory is located in the National Centre for Medical Genetics at Our Lady's Hospital for Sick Children. Our research is focused on the molecular genetics of inherited disorders and on measuring and improving the quality of molecular genetic testing in medical laboratories.
| Sponsor : EC Framework
Title : Genetic testing in Europe- Network for the further development, harmonization, validation and standardizatio of services (EuroGentest2)
Start Date / End Date : 01-JAN-11 / 31-DEC-13
| Sponsor : Enterprise Ireland (EI)
Title : Joint Research Centre (JRC) - Institute for Health and Consumer Protection, Ispra, Italy - exploratory visit - 10/11/2009
Start Date / End Date : 08-NOV-09 / 10-NOV-09