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James Jones

Professor of Anatomy

School Of Medicine & Medical Science
Health Sciences Centre
Belfield
Dublin 4

Tel: +353 1 7166622
Email: james.jones@ucd.ie

Biography

2012-present Professor of Anatomy, UCD
2002-2012 Senior Lecturer in Physiology UCD
2002  MD (NUI) by published work
1995-2002 College Lecturer Physiology UCD
1993-1995 Wellcome Trust Lectureship RFHSM London
1993  PhD University of London
1989-1990 Lecturer in Physiology University College Dublin
1989 BSc(Hons) Physiology First class honours University College Dublin
1987 MB BCh BAO University College Dublin





Professional

Honours and Awards

Year: 2005.
Title: Michael De Burgh Daly prize lecture (The physiological society)
Year: 2002.
Title: UCD Presidents Research Award
Year: 1993.
Title: Young Investigator of the Year - DeCastro-Heymans-Neil Medal (International Soc for arterial chemoreception)

Associations

Association: The Journal of Physiology, Function/Role: Ethical editor
         

Employment

Employer: Sligo General Hospital
Position: House Officer
Employer: Mater Hospital Dublin
Position: House Officer
Employer: University College Dublin
Position: Medical Demonstrator
Employer: University College Dublin
Position: Assistant Lecturer
Employer: Royal Free School of Medicine
Position: Research Fellow
Employer: Royal Free Hospital School of Medicine
Position: Lecturership
Employer: University College Dublin
Position: Lecturer

Education

Year 2002 Institution: NUI
Qualification: MD Subject: Physiology
Year 1987 Institution: University College Dublin
Qualification: MB, BCh, BAO Subject:
Year 1993 Institution: University of London
Qualification: PhD Subject:
Year 1990 Institution: University College Dublin
Qualification: BSc Subject:
       

Other Activities

I was the external exmainer for BSc (Anatomy) in the University of Leeds (2005-08).
I am currently the external examiner for the BSc (Anatomy) degree at the
University of Birmingham Leeds (2015-15).
Senior ethical editor for The Journal of Physiology

Publications

 

Book Chapters

Edge D, Bradford A, Jones JFX, O'Halloran KD; (2011) 'Chronic intermittent hypoxia alters rat genioglossus motor unit properties' In: Edge D, Bradford A, Jones JFX, O'Halloran KD; (eds). International Society for Arterial Chemoreception. [Details]
O'Connor ET, O'Halloran KD, Jones JF. (2012) 'Propranolol does not affect the hindlimb vasodilatation elicited by stimulation of superior laryngeal nerve paraganglia' In: O'Connor ET, O'Halloran KD, Jones JF. (eds). Adv Exp Med Biol. New York, Boston: Kluwer Academic/Plenum. [DOI] [Details]
 

Peer Reviewed Journals

Skelly JR, Rowan SC, Jones JF, O'Halloran KD (2013) 'Upper airway dilator muscle weakness following intermittent and sustained hypoxia in the rat: effects of a superoxide scavenger'. Physiological research / Academia Scientiarum Bohemoslovaca, 62 (2):187-196. [Details]
Carberry JC, McMorrow C, Bradford A, Jones JF, O'Halloran KD (2013) 'Effects of sustained hypoxia on sternohyoid and diaphragm muscle during development'. EUR RESPIR J, . [DOI] [Details]
Jones JF (2013) 'The impact of impact factors and the ethics of publication'. Journal Of Medicine, 182 (4). [DOI] [Details]
Jones JF (2013) 'A bicentennial celebration of the birth of Claude Bernard'. Journal Of Medicine, 182 (4). [DOI] [Details]
Edge D, Bradford A, Jones JF, O'Halloran KD. (2012) 'Chronic intermittent hypoxia alters genioglossus motor unit discharge patterns in the anaesthetized rat'. Advances in experimental medicine and biology, . [DOI] [Details]
O'Connor ET, O'Halloran KD, Jones JF (2012) 'Pro-inflammatory cytokines do not affect basal or hypoxia stimulated discharge of rat vagal paraganglia'. Experimental Physiology, . [DOI] [Details]
Griffin KM, O'Herlihy C, O'Connell PR, Jones JF (2012) 'Combined ischemic and neuropathic insult to the anal canal in an animal model of obstetric-related trauma'. Diseases of the Colon &Amp; Rectum, 55 (1):32-41. [DOI] [Details]
Skelly JR, Edge D, Shortt CM, Jones JF, Bradford A, O'Halloran KD (2012) 'Respiratory control and sternohyoid muscle structure and function in aged male rats: decreased susceptibility to chronic intermittent hypoxia'. Respiratory physiology & neurobiology, 180 (2-3):175-182. [DOI] [Details]
Buffini M, O'Halloran KD, O'Herlihy C, O'Connell PR, Jones JF (2012) 'Comparison of the motor discharge to the voluntary sphincters of continence in the rat'. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 24 (4):1-84. [DOI] [Details]
Evers J, Buffini M, Craven S, O'Connell R, Jones JF (2012) 'Is there a nitrergic modulation of the rat external anal sphincter?'. Experimental Physiology, . [DOI] [Details]
Jones JF (2012) 'Highlights in basic autonomic neurosciences: The vagus and the ventricles'. Autonomic neuroscience : basic & clinical, 170 (1-2):1-2. [DOI] [Details]
Edge D, Bradford A, Jones JF, O'Halloran KD (2012) 'Chronic intermittent hypoxia alters genioglossus motor unit discharge patterns in the anaesthetized rat'. Frontiers in Modeling and Control of Breathing, 758 :295-300. [DOI] [Details]
O'Connor ET, O'Halloran KD, Jones JF (2012) 'Propranolol does not affect the hindlimb vasodilatation elicited by stimulation of superior laryngeal nerve paraganglia'. Frontiers in Modeling and Control of Breathing, 758 :273-277. [DOI] [Details]
O'Connor ET, O'Halloran KD, Jones JF. (2012) 'Pro-inflammatory cytokines do not affect basal or hypoxia stimulated discharge of rat vagal paraganglia'. Experimental Physiology, . [Details]
Griffin KM, O'Herlihy C, O'Connell PR, Jones JF (2012) 'COMBINED ISCHEMIC AND NEUROPATHIC INSULT TO THE ANAL CANAL IN AN ANIMAL MODEL OF OBSTETRIC-RELATED TRAUMA'. Diseases of the colon and rectum, 55 :32-41. [Details]
Griffin KM, Pickering M, O'Herlihy C, O'Connell PR, Jones JF; (2011) 'Sacral nerve stimulation increases activation of the primary somatosensory cortex by anal canal stimulation in an experimental model'. The British journal of surgery, 98 (8):1160-1169. [DOI] [Details]
Peirce C, O'Herlihy C, O'Connell PR, Jones JF; (2011) 'Effect of injury on S1 dorsal root ganglia in an experimental model of neuropathic faecal incontinence'. The British journal of surgery, 98 (8):1155-1159. [DOI] [Details]
Skelly JR, Edge D, Shortt CM, Jones JFX, Bradford A, O'Halloran KD; (2011) 'Tempol ameliorates pharyngeal dilator muscle dysfunction in a rodent model of chronic intermittent hypoxia'. American Journal of Respiratory Cell and Molecular Biology, . [Details]
Skelly JR, O'Connell RA, Jones JFX, O'Halloran KD; (2011) 'Structural and functional properties of an upper airway dilator muscle in aged obese male rats'. Respiration, . [Details]
Buffini M, O'Halloran KD, O'Herlihy C, O'Connell R, Jones JF; (2010) 'Comparison of the contractile properties, oxidative capacities and fibre type profiles of the voluntary sphincters of continence in the rat'. Journal of Anatomy, 217 (3):187-195. [DOI] [Details]
Buffini M, O'Halloran KD, O'Herlihy C, O'Connell R, Jones JF; (2010) 'Comparison of the contractile properties, oxidative capacities and fibre type profiles of the voluntary sphincters of continence in the rat'. Journal of Anatomy, 217 (3):187-195. [Details]
Kelly, ME,Blau, CW,Griffin, KM,Gobbo, OL,Jones, JFX,Kerskens, CM; (2010) 'Quantitative functional magnetic resonance imaging of brain activity using bolus-tracking arterial spin labeling'. Blood, 30 :913-922. [DOI] [Details]
Peirce, C,Alexander, LE,O'Herlihy, C,O'Connell, PR,Jones, JFX; (2010) 'Central Representation of the Inferior Rectal Nerve of the Rat'. Diseases of the Colon &Amp; Rectum, 53 :315-320. [DOI] [Details]
Griffin, KM,Blau, CW,Kelly, ME,O'Herlihy, C,O'Connell, PR,Jones, JFX,Kerskens, CM; (2010) 'Propofol allows precise quantitative arterial spin labelling functional magnetic resonance imaging in the rat'. Neuroimage, 51 (4):1395-1404. [DOI] [Details]
Healy, C. F., McMorrow, C., O'Herlihy, C., O'Connell, P. R., Jones, J. F. X., ; (2008) 'External anal sphincter fatigue is not improved by N-acetylcysteine in an animal model'. Neurogastroenterology and Motility, 20 (6):719-724. [Details]
Jones JF, Healy CF, McMorrow C, O'Herlihy C, O'Connell PR, ; (2008) 'External anal sphincter fatigue is not improved by N-acetylcysteine in an animal model'. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 6 (NA):719-724. [DOI] [Details]
Jones JF, Healy CF, O'Herlihy C, O'Brien C, O'Connell PR, ; (2008) 'Experimental models of neuropathic fecal incontinence: an animal model of childbirth injury to the pudendal nerve and external anal sphincter'. Diseases of the Colon &Amp; Rectum, 11 (NA):1619-161. [DOI] [Details]
Jones JF, Peirce C, Healy CF, O'Herlihy C, O'Connell PR, ; (2008) 'Effect of prolonged vaginal distention and sphincter transection on physiologic function of the external anal sphincter in an animal model'. Obstetrics & Gynecology, 4 (NA):943-91. [DOI] [Details]
Jones JF, Peirce C, Healy CF, O'Herlihy C, O'Connell PR, ; (2008) 'Effect of prolonged vaginal distention and sphincter transection on physiologic function of the external anal sphincter in an animal model'. Obstetrics & Gynecology, 4 (NA):943-91. [DOI] [Details]
Pickering, M,Jones, JFX; (2007) 'Comparison of the motor discharge to the crural and costal diaphragm in the rat'. Respiratory Physiology &Amp; Neurobiology, 159 :21-27. [DOI] [Details]
Sweeney, CM,Jones, JFX,Bund, SJ; (2007) 'Adrenoceptor and cholinoceptor modulation of rat pulmonary vein cardiac muscle contractility'. Vasc Pharmacol, 46 :166-170. [DOI] [Details]
Sweeney, CM; Jones, JFX; Bund, SJ; ; (2007) 'Adrenoceptor and cholinoceptor modulation of rat pulmonary vein cardiac muscle contractility'. Vascular Pharmacology, 46 (3):166-170. [Details]
Pickering, M,Campion, D,Jones, JFX; (2004) 'A gastrointestinal role for the amphibian 'diaphragm' of Xenopus laevis'. Journal of Zoology, 264 :45-51. [Details]
Pickering, M; Campion, D; Jones, JFX; ; (2004) 'A gastrointestinal role for the amphibian 'diaphragm' of Xenopus laevis'. Journal of Zoology, 264 (NA):45-51. [Details]
O'Leary, DM,Murphy, A,Pickering, M,Jones, JFX; (2004) 'Arterial chemoreceptors in the superior laryngeal nerve of the rat'. Respiratory Physiology &Amp; Neurobiology, 141 :137-144. [DOI] [Details]
Pickering, M and Campion, D and Jones, JFX; (2004) 'A gastrointestinal role for the amphibian `diaphragm' of Xenopus laevis'. JOURNAL OF ZOOLOGY, 264 (Part 1):45-51. [Details]
O'Leary, DM and Murphy, A and Pickering, M and Jones, JFX; (2004) 'Arterial chemoreceptors in the superior laryngeal nerve of the rat'. RESPIRATORY PHYSIOLOGY \& NEUROBIOLOGY, 141 (2):137-144. [DOI] [Details]
Hughes, K, Pickering, M, O'Leary, DM, Bradford, A, O'Regan, RG, Jones, JFX, ; (2003) 'The paraganglia of the rat superior laryngeal nerve'. Advances in experimental medicine and biology, 536 (NA):239-246. [Details]
O'Leary, DM,Jones, JFX; (2003) 'Discharge patterns of preganglionic neurones with axons in a cardiac vagal branch in the rat'. Experimental Physiology, 88 :711-723. [Details]
Jones, JFX and O'Leary, DM and Pickering, M; (2003) 'Vagal control of the cranial venae cavae of the rat heart'. EXPERIMENTAL PHYSIOLOGY, 88 (3):329-334. [Details]
Pickering, M and Campion, D and Jones, JFX; (2002) 'Reflex cardiorespiratory effects of nociceptive oesophageal distension in the decerebrate rat'. EXPERIMENTAL PHYSIOLOGY, 87 (1):41-48. [Details]
Pickering, M,Campion, D,Jones, JFX; (2002) 'Reflex cardiorespiratory effects of nociceptive oesophageal distension in the decerebrate rat'. EXPERIMENTAL PHYSIOLOGY, 87 (NA):41-48. [Details]
Pickering, M and Jones, JFX; (2002) 'The diaphragm: two physiological muscles in one'. JOURNAL OF ANATOMY, 201 (4):305-312. [Details]
Al-Ghamdi, MSAD,Jones, JFX,Taylor, EW; (2001) 'Evidence of a functional role in lung inflation for the buccal pump in the agamid lizard Uromastyx aegyptius microlepis'. Experimental Biology, 204 :521-531. [Details]
Jones JF, ; (2001) 'Vagal control of the rat heart'. Experimental Physiology, 6 (NA):797-801. [Details]
Wang, Y,Jones, JFX,Jeggo, RD,Daly, MD,Jordan, D,Ramage, AG; (2000) 'Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats'. The Journal of physiology, 526 :157-165. [Details]
Brophy, S,Ford, TW,Carey, M,Jones, JFX; (1999) 'Activity of aortic chemoreceptors in the anaesthetized rat'. The Journal of physiology, 514 :821-828. [Details]
Jones JF, Brophy S, Ford TW, Carey M, ; (1999) 'Activity of aortic chemoreceptors in the anaesthetized rat'. The Journal of physiology, (NA):821-828. [Details]
Jordan D, Jones JF, Wang Y, ; (1998) 'Activity of C fibre cardiac vagal efferents in anaesthetized cats and rats'. The Journal of physiology, (NA):869-880. [Details]
Jones, JFX, Wang, Y, Jordan, D, ; (1998) 'Activity of C fibre cardiac vagal efferents in anaesthetized cats and rats'. Journal of Physiology-London, 507 (3):869-880. [Details]
Buffini M, O'Halloran KD, O'Herlihy C, O'Connell R, Jones JFX; (2010) 'Comparison of the contractile properties, oxidative capacities and fibre type profiles of the sphincters of continence in the rat'. Journal of Anatomy, 217 :187-195. [Details]
McMorrow C, Fredsted A, O'Connell RA, Carberry J, Bradford A, Jones JFX and O'Halloran KD; (2010) 'Chronic hypoxia increases rat diaphragm muscle endurance and Na+-K+ ATPase pump content'. European Respiratory Journal, 37 (6):1474-1481. [Details]
MacGrory B, O'Connor ET, O'Halloran KD, Jones JFX; (2010) 'Effects of pro-inflammatory cytokines on the discharge rate of vagal nerve paraganglia in the rat'. Respiratory Physiology & Neurobiology, 171 :122-127. [Details]
Skelly JR, Bradford A, Jones JFX, O'Halloran KD; (2010) 'Superoxide scavengers improve rat pharyngeal dilator muscle performance'. American Journal of Respiratory Cell and Molecular Biology, 42 :725-731. [Details]
Jones JF, Banahan M, Peirce C, Buffini M, O'Herlihy C, O'Connell PR, ; (2010) 'Atrophy of the sphincters of continence in an experimental model'. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, . [DOI] [Details]
Jones JF, Peirce C, Healy CF, O'Herlihy C, O'Connell PR, ; (2009) 'Reduced somatosensory cortical activation in experimental models of neuropathic fecal incontinence'. Diseases of the Colon &Amp; Rectum, 52 (8):1417-1422. [DOI] [Details]
Jones JF, ; (2009) 'Cardiac defibrillator neurones'. The Journal of physiology, 587 (Pt 12). [DOI] [Details]
C. Peirce, C.F. Healy, C. O'Herlihy, P.R. O'Connell, J.F.X. Jones ; (2008) 'Peripheral and central effects of injury in rat models of neuropathic faecal incontinence'. Colorectal Disease, 10 (Suppl 1):4-4. [Details]
M Buffini, C O'Herlihy, PR O'Connell & JFX Jones ; (2008) 'Fatigability of isolated rat external urethral and anal sphincters'. IRISH JOURNAL OF MEDICAL SCIENCE, 177 (Suppl 11):S376-S377. [Details]
Jones JF, ; (2008) 'Adventures in pulmonary physiology: the action of drugs on the pulmonary circulation by Alcock, Berry & Daly (1935)'. Experimental Physiology, 3 (NA):316-318. [DOI] [Details]
Sweeney, CM, Jones, JFX, Bund, SJ, ; (2007) 'Adrenoceptor and cholinoceptor modulation of rat pulmonary vein cardiac muscle contractility'. Vasc Pharmacol, 46 (3):166-170. [DOI] [Details]
Jones JF, ; (2007) 'A moving-invisible-needle in a haystack experiment'. Experimental Physiology, 6 (NA). [DOI] [Details]
Pickering M, Jones JF.; (2007) 'Comparison of the motor discharge to the crural and costal diaphragm in the rat'. Respiratory Physiology & Neurobiology, 159 (1):21-27. [Details]
Pickering M, Jones JF, O'Leary DM, ; (2003) 'Vagal control of the cranial venae cavae of the rat heart'. Experimental Physiology, 3 (NA):329-334. [Details]
Jones JF, ; (2000) 'Aortic body chemoreflex of the anaesthetized rat. Electrophysiological, morphological, and reflex studies'. Advances in experimental medicine and biology, (NA):789-792. [Details]
de Burgh Daly M, Jones JF, ; (1997) 'Reflex cardiac dromotropic responses to stimulation of the carotid and aortic chemoreceptors in the anaesthetized cat'. The Journal of physiology, (NA):461-467. [Details]
JONES, JFX, MCKEOGH, D, NOLAN, P, OREGAN, R, ; (1993) 'THE EFFECT OF ESOPHAGEAL DISTENSION ON DIAPHRAGM AND LARYNGEAL EMG IN THE ANESTHETIZED CAT'. Journal of Physiology-London, 467 (NA):151-151. [Details]
O'Leary, DM; Murphy, A; Pickering, M; Jones, JFX; ; (2004) 'Arterial chemoreceptors in the superior laryngeal nerve of the rat'. Respiratory Physiology &Amp; Neurobiology, 141 (2):137-144. [Details]
Pickering, M; Campion, D; Jones, JFX; ; (2004) 'A gastrointestinal role for the amphibian 'diaphragm' of Xenopus laevis'. Journal of Zoology, 264 (NA):45-51. [Details]
O'Leary, DM; Jones, JFX; ; (2003) 'Peripheral chemoreceptor input to cardiac vagal preganglionic neurones in the anaesthetised rat'. Chemoreception: From Cellular Signalling to Functional Plasticity, 536 (NA):461-466. [Details]
O'Leary, DM; Jones, JFX; ; (2003) 'Discharge patterns of preganglionic neurones with axons in a cardiac vagal branch in the rat'. Experimental Physiology, 88 (6):711-723. [Details]
Hughes, K; Pickering, M; O'Leary, DM; Bradford, A; O'Regan, RG; Jones, JFX; ; (2003) 'The paraganglia of the rat superior laryngeal nerve'. Chemoreception: From Cellular Signalling to Functional Plasticity, 536 (NA):239-246. [Details]
Tak, HH; Jones, JFX; ; (2002) 'Vagal control of the rat cranial venae cavae'. Journal of Physiology-London, 539 (NA):104-105. [Details]
Pickering, M; Jones, JFX; ; (2002) 'The diaphragm: two physiological muscles in one'. Journal of Anatomy, 201 (4):305-312. [Details]
Jones, J.F.X.; (2001) 'Vagal control of the rat heart'. Experimental Physiology, 86 (6):807-811. [Details]
Al-Ghamdi, M.S.A.D., Jones, J.F.X. and Taylor, E.W.; (2001) 'Evidence of a functional role in lung inflation for the buccal pump in the agamid lizard Uromastyx aegyptius microlepis'. Experimental Biology, 204 :521-531. [Details]
Al-Ghamdi, MSAD; Jones, JFX; Taylor, EW; ; (2001) 'Evidence of a functional role in lung inflation for the buccal pump in the agamid lizard Uromastyx aegyptius microlepis'. Experimental Biology, 204 (3):521-531. [Details]
Wang, Y; Jones, JFX; Jeggo, RD; Daly, MD; Jordan, D; Ramage, AG; ; (2000) 'Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats'. Journal of Physiology-London, 526 (1):157-165. [Details]
Brophy, S., Ford, T.W., Carey, M., and Jones, J.F.X.; (1999) 'Activity of aortic chemoreceptors in the anaesthetized rat'. Journal of Physiology, 514 (3):821-828. [Details]
Brophy, S; Ford, TW; Carey, M; Jones, JFX; ; (1999) 'Activity of aortic chemoreceptors in the anaesthetized rat'. Journal of Physiology-London, 514 (3):821-828. [Details]
Jones, J.F.X., and Daly, M. de Burgh; (1997) 'Reflex cardiac dromotropic responses to stimulation of the carotid and aortic chemoreceptors in the anaesthetized cat'. Journal of Physiology, 502 :461-467. [Details]
Jones, J.F.X.,Wang,Y and Jordan, D.; (1995) 'The action of cardiac vagal C-fibres on heart rate in the anaesthetised cat, rat and rabbit'. Journal of Physiology, 489 :203-214. [Details]
Jones, J.F.X., Martin, G.R. and Ramage, A.G.; (1995) 'Evidence that 5-HT1D receptors mediate inhibition of sympathetic ganglionic transmission in anaesthetized cats'. British Journal of Pharmacology, 116 :1715-1717. [Details]

Other Journals

Peirce C, Alexander LE, Buffini, M. O'Herlihy C, O'Connell PR, Jones JF.; (2009) 'Investigation of the nerve supply to the external anal sphincter (EAS) in the female rat' British Journal of Surgery 96(S5) :37 . [Details]
Kelly ME, Blau CW, Griffin KM, Gobbo OL, Jones JF, Kerskens CM.; (2010) 'Quantitative functional magnetic resonance imaging of brain activity using bolus-tracking arterial spin labeling' J Cereb Blood Flow Metab 30 (5) :913-922. [Details]

Conference Publications

McMorrow C, Bradford A, Jones JFX, O'Halloran KD; (2011) Improved anoxic tolerance in chronic hypoxic rat diaphragm is nitric oxide dependent International Hypoxia Symposium (Lake Louise, Canada) [Details]
O'Connor T, O'Halloran KD, Jones JFX; (2011) Vagal paraganglia of the rat International Hypoxia Symposium (Lake Louise, Canada) [Details]
C. McMorrow, A. Fredsted, J. Carberry, R. O'Connell, A. Bradford, J. Jones, K. ; (2010) Chronic hypoxia increases rat diaphragm muscle endurance and Na+-K+ ATPase pump content Proc Physiol Soc [Details]
O'Connor T, O'Halloran KD, Jones JFX; (2010) The cardiorespiratory effects of stimulation of superior laryngeal nerve paraganglia in the urethane anaesthetised rat Physiological Society Themed Meeting (Birmingham): Proc Physiol Soc 20: C19 [Details]
M. Buffini, C. O'Herlihy, R. O'Connell, J. Jones ; (2009) Fibre size and oxidative capacity of the external anal and urethral sphincters Proc Physiol Soc [Details]
. T. O'Connor, K. D. O'Halloran, J. F. Jones. ; (2010) The Cardiorespiratory Reflex Effects of Stimulation of Superior Laryngeal Nerve Paraganglia in the Urethane Anaesthetised Rat J Physiol (2010) Proc Physiol Soc 20; C19 and PC19 Proc Physiol Soc [Details]
Kelly ME, Blau CW, Gobbo OL, Griffin KM, Jones JFX, Kerskens CM. ; (2010) Quantitative functional magnetic resonance imaging with bolus-tracking arterial spin labelling.Irish Journal of Medical Science 2010, Vol 179, supplement 3, S107-108 Irish Journal of Medical Science [Details]
Peirce C, O¿Herlihy, C O¿Connell PR, Jones JFX. ; (2010) Faecal incontinence: where is the sense in it all? Irish Journal of Medical Science 2010, Vol 179, supplement 1, S1 Irish Journal of Medical Science 2010 [Details]
O¿Connor ET, O¿Halloran KD, Jones JFX. ; (2010) The chemoreflex function of the superior laryngeal nerve paraganglia in the rat . In: Irish Journal of Medical Science 2010, Vol 179, Supplement 7S284 eds. Irish Journal of Medical Science [Details]
Pierce C, Alexander LE, Buffini, M. O'Herlihy C, O'Connell PR, Jones JF.; (2009) Investigation of the nerve supply to the external anal sphincter (EAS) in the female rat.96(S5) :37 British Journal of Surgery [Details]
M. Buffini, C. O'Herlihy, R. O'Connell, J. Jones ; (2009) Fibre size and oxidative capacity of the external anal and urethral sphincters Proc Physiol Soc [Details]
E. T. O'Connor, K. D. O'Halloran, J. Jones ; (2009) The Effect of IL-6 on the Hypoxic Sensitivity of Vagal Nerve Paraganglia in the Rat Proc Physiol Soc [Details]
J. F. Jones, C. Peirce, K. Griffin, M. Buffini, C. O'Herlihy, R. O'Connell; (2009) Animal models of neuropathic faecal incontinence Proc Physiol Soc [Details]
K. M. Griffin, C. OHerlihy, R. OConnell, J. F. Jones; (2009) Brief sacral nerve root stimulation and tibial nerve stimulation increases cortical somatosensory evoked potential in the rat Proc Physiol Soc [Details]
K. M. Griffin, C. O¿Herlihy, R. O¿Connell, J. Jones ; (2009) Brief sacral nerve root stimulation increases somatosensory cortical activation in the rat Proc Physiol Soc [Details]
Peirce C, Alexander LE, O'Herlihy C, O'Connell PR, Jones JFX; (2009) Activating transcription factor 3 (ATF-3) as a marker of injury in experimental models of neuropathic faecal Irish Journal of Medical Science [Details]
McMorrow C, Fredsted A, Carberry J, O'Connell RA, Bradford A, Jones JFX, O'Halloran KD; (2010) Chronic hypoxia increases rat diaphragm muscle endurance and Na+-K+ ATPase pump content Physiological Society Main Meeting (Manchester) Proc Physiol Soc 19: PC26 [Details]
Healy, C.F., Jones, J.F.X., O'Brien, C., O'Herlihy, C. O'Connell, P.R.; (2006) The development of an acute animal model to simulate pelvic floor injury during childbirth The Society of Academic Research in Surgery [Details]
Healy, C.F., Jones, J.F.X, O'Brien, C., O'Herlihy, C. O'Connell, P.R.; (2006) The development of an acute animal model to simulate pelvic floor injury during childbirth Society of Coloproctology of Great Britain and Ireland [Details]
Holleran, L & Jones JFX; (2007) The sensitivity of isolated perfused laryngeal nerve fibres in the rat RAMI summer meeting [Details]
Healy, C.F., Jones, J.F.X., O'Brien, C., O'Herlihy, C. O'Connell, P.R.; (2006) The development of an acute animal model to simulate pelvic floor injury during childbirth Royal Academy of Medicine Ireland (RAMI) Winner of Registrar's Prize, Royal College of Surgeons [Details]
Healy, C.F., Jones, J.F.X., O'Brien, C., O'Herlihy, C. O'Connell, P.R.; (2006) The development of an acute animal model to simulate pelvic floor injury during childbirth The Association of Coloproctology of Great Britain and Ireland Annual Meeting [Details]
Jones, J.F.X., Shakespeare, I., Healy, C.F., Mitchell, P., Whealan, R., O'Herlihy, C. O'Connell, P.R.; (2005) Neural Control of rat external anal sphincter: a role for nitric oxide? Irish Society of Gastroenterology [Details]
   

Editorial

Jones, JFX; (2009) Cardiac defibrillator neurones. Editorial [DOI] [Details]
Jones, JFX; (2007) A moving-invisible-needle in a haystack experiment. Editorial [DOI] [Details]
                                                                                   

Research

Research Interests

My current funded research projects involve
1. Rat models of neuropathic faecal incontinence and the mechanism of action of sacral neruomodulation. In collaboration with Professors Ronan O'Connell and Colm O'Herlihy, I am examining the central nervous system re-arrangements that follow pudendal nerve injury. In addition, we are stimulating lumbosacral nerve roots in humans and rats to refine an emerging therapy for certain forms of faecal incontinence (SFI)
2. Effect of chronic intermittent hypoxia on sympathetic vasomotor control.
I am collaborating with Dr Ken O'Halloran on the effects of cyclical hypoxia on sympathetic vasomotor discharge, vascular sensitivity to sympathetic chain stimulation and vascular sympathetic nerve density (IRCSET)
3. Human neurophysiology studies performed in collaboration with Professor Ronan O'Connell and Dr Sean Connolly. Patients with faecal incontinence who are selected for sacral neuromodulation will have EEG recordings to measure somatosensory cortical potentials evoked by stimulation of ano-rectal region (BDRF and Medtronic Inc.)

Research Projects

Sponsor : Medtronic Inc.
Title : Reflex and behavioural studies of faecal continence and incontinence in an animal model and optimisation of frequency parameters of sacral neuromodulation
Start Date / End Date : 22-JUN-12 / 01-JAN-15
Sponsor : University College Dublin Foundation Ltd.
Title : A new model for studying eye development
Start Date / End Date : 01-JAN-13 / 31-DEC-13
Sponsor : Science Foundation Ireland (SFI)
Title : The effect of sacral neuromodulation on inputs to the somatosensory cortex
Start Date / End Date : 01-SEP-11 / 31-AUG-15
Sponsor : Bowel Disease Research Foundation (BDRF)
Title : The effect of sacral neuromodulation on cortical processing of anal canal inputs in patients with faecal incontinence
Start Date / End Date : 01-OCT-11 / 01-OCT-12
Sponsor : Health Research Board (HRB)
Title : Mechanism of laryngeal sensing of expired carbon dioxide
Start Date / End Date : 01-OCT-05 / 01-OCT-07
Sponsor : The Wellcome Trust (WT)
Title : Classification of cardiac vagal preganglionic neurones
Start Date / End Date : 01-MAR-00 / 28-FEB-03
Sponsor : Health Research Board (HRB)
Title : Central control of the crural diaphragm
Start Date / End Date : 01-OCT-99 / 30-SEP-02
Sponsor : Health Research Board (HRB)
Title : No Project title to migrate.
Start Date / End Date : 01-JUN-98 / 31-MAY-99
Sponsor : The Wellcome Trust (WT)
Title : No Project title to migrate.
Start Date / End Date : 01-OCT-96 / 30-SEP-99
Sponsor : British Council
Health Research Board (HRB)
Title : No Project title to migrate.
Start Date / End Date : 01-MAY-96 / 08-MAY-96
Sponsor : Wellcome Trust, UK
Title : The physiological role of paraganglia of the superior laryngeal nerve of the rat
Start Date / End Date : 01-JUN-06 / 01-JUN-08
Sponsor : Mater Misericordiae University Hospital
Title : The effect of pudendal nerve injury on sensory neurons in an animal model of neuropathic faecal incontinence
Start Date / End Date : 01-OCT-08 / 01-OCT-09
Sponsor : Royal College of Surgeons Ireland (RCSI)
Title : The effect of pudendal nerve injury on sensory neurons in animal models of neuropathic faecal incontinence
Start Date / End Date : 01-OCT-08 / 01-OCT-09
Sponsor : University College Dublin (UCD)
Title : Metabolic function in an animal model of sleep apnoea
Start Date / End Date : 26-MAY-08 / 01-DEC-09
Sponsor : Health Research Board (HRB)
Title : The action of sacral neuromodulation on an animal model of neuropathic faecal incontinence
Start Date / End Date : 01-SEP-07 / 31-AUG-10
Sponsor : University College Dublin (UCD)
Title : Role of nitric oxide in cardiac vagal ganglia
Start Date / End Date : 01-JUN-02 / 31-MAY-04

Recent Postgraduates

MD: Ciaran Healy (2007)

PhD:  Lisa Fleming (2008)

MD: Colin Peirce (2010)

PhD: Karen Griffin (2011)

PhD: Maria Buffini (2012)

PhD: Edward O'Connor (2012) 

PhD: Deirdre Edge (2012)

Current Postgraduate Students

Judith Evers, Doctor of Philosophy (PhD)   -   Thesis Supervisor
Michael O Reilly, Master of Science (MSc)   -   Thesis Supervisor
Liam Devane, Medicine (MD)   -   Thesis Supervisor

Collaborators

Internal Collaborators

Professors Ronan O'Connell (Surgery) and Colm O'Herlihy (Obstetrics and Gynaecology) co-applicants on funded HRB project grant.

Dr Ken O'Halloran (Physiology, UCC)

Dr Sean Connolly (Clinical neurophysiology, St Vincent's hospital)

Dr Keith Murphy (Pharmacology,UCD)

Dr Mark Pickering (Physiology,UCD)  

External Collaborators

Dr Charlie Knowles,
Academic Surgical Unit,
3rd Floor Alexandra Wing,
Royal London Hospital,
Whitechapel,
London E1 1BB.