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Researchers at UCD

researcher

Pauline Rudd

Adjunct Professor

Research Administration
UCD Research Building
Belfield
Dublin 4

Tel: +353 1 7166728
Email: pauline.rudd@ucd.ie

Publications

     

Peer Reviewed Journals

Muindi, K.,Cernadas, M.,Watts, G. F.,Royle, L.,Neville, D. C.,Dwek, R. A.,Besra, G. S.,Rudd, P. M.,Butters, T. D.,Brenner, M. B.; (2010) 'Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected]'. PNAS, 107 (7):3052-3057. Available Online [Details]
McVicar, C. M.,Colhoun, L. M.,Abrahams, J. L.,Kitson, C. L.,Hamilton, R.,Medina, R. J.,Durga, D.,Gardiner, T. A.,Rudd, P. M.,Stitt, A. W.; (2010) 'Differential modulation of angiogenesis by erythropoiesis-stimulating agents in a mouse model of ischaemic retinopathy'. PLoS ONE, 5 (7):e11870-e11870-16. Available Online [Details]
Sarrats, A.,Saldova, R.,Comet, J.,O'Donoghue, N.,de Llorens, R.,Rudd, P. M.,Peracaula, R.; (2010) 'Glycan Characterization of PSA 2-DE Subforms from Serum and Seminal Plasma'. OMICS: A Journal of Integrative Biology, 14 (4):465-474. Available Online [DOI] [Details]
Marino, K.,Bones, J.,Kattla, J. J.,Rudd, P. M.; (2010) 'A systematic approach to protein glycosylation analysis: a path through the maze'. Nature Chemical Biology, 6 (10):713-723. Available Online [Details]
Lauc, G.,Rudan, I.,Campbell, H.,Rudd, P. M.; (2010) 'Complex genetic regulation of protein glycosylation'. Molecular BioSystems, 6 (22):329-335. Available Online [Details]
Harvey, D. J.,Rudd, P. M.; (2010) 'Identification of by-products formed during the release of N-glycans with protein N-glycosidase F in the presence of dithiothreitol'. Journal of Mass Spectrometry, 45 (77):815-819. Available Online [Details]
Stanta, J. L.,Saldova, R.,Struwe, W. B.,Byrne, J. C.,Leweke, F. M.,Rothermund, M.,Rahmoune, H.,Levin, Y.,Guest, P. C.,Bahn, S.,Rudd, P. M.; (2010) 'Identification of N-glycosylation changes in the CSF and serum in patients with schizophrenia'. Journal of Proteome Research, 9 (99):4476-4489. Available Online [Details]
Saldova, R.,Fan, Y.,Fitzpatrick, J. M.,Watson, R. W.,Rudd, P. M.; (2011) 'Core fucosylation and {alpha}2-3 sialylation in serum N-glycome is significantly increased in prostate cancer comparing to benign prostate hyperplasia'. Glycobiology, 21 (1). Available Online [Details]
Pucic, M.,Pinto, S.,Novokmet, M.,Knezevic, A.,Gornik, O.,Polasek, O.,Vlahovicek, K.,Wang, W.,Rudd, P. M.,Wright, A. F.,Campbell, H.,Rudan, I.,Lauc, G.; (2010) 'Common aberrations from the normal human plasma N-glycan profile'. Glycobiology, 20 (8):970-975. Available Online [Details]
Pierce, A.,Saldova, R.,Abd Hamid, U. M.,Abrahams, J. L.,McDermott, E. W.,Evoy, D.,Duffy, M. J.,Rudd, P. M.; (2010) 'Levels of specific glycans significantly distinguish lymph node-positive from lymph node-negative breast cancer patients'. Glycobiology, 20 (10):1283-1288. Available Online [Details]
Knezevic, A.,Gornik, O.,Polasek, O.,Pucic, M.,Redzic, I.,Novokmet, M.,Rudd, P. M.,Wright, A. F.,Campbell, H.,Rudan, I.,Lauc, G.; (2010) 'Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans'. Glycobiology, 20 (8):959-969. Available Online [Details]
Barrabes, S.,Sarrats, A.,Fort, E.,De Llorens, R.,Rudd, P. M.,Peracaula, R.; (2010) 'Effect of sialic acid content on glycoprotein pI analyzed by two-dimensional electrophoresis'. Electrophoresis, 31 (17):2903-2912. Available Online [Details]
Tharmalingam, T.,Marino, K.,Rudd, P. M.; (2010) 'Platform technology to identify potential disease markers and establish heritability and environmental determinants of the human serum N-glycome'. Carbohydrate Research, 345 (10):1280-1282. Available Online [Details]
Liu, L.,Telford, J. E.,Knezevic, A.,Rudd, P. M.; (2010) 'High-throughput glycoanalytical technology for systems glycobiology'. Biochemical Society Transactions, 38 (55):1374-71374. Available Online [Details]
Ercan, A.,Cui, J.,Chatterton, D. E.,Deane, K. D.,Hazen, M. M.,Brintnell, W.,O'Donnell, C. I.,Derber, L. A.,Weinblatt, M. E.,Shadick, N. A.,Bell, D. A.,Cairns, E.,Solomon, D. H.,Holers, V. M.,Rudd, P. M.,Lee, D. M.; (2010) 'Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis'. Arthritis and Rheumatism, 62 (88):2239-2248. Available Online [Details]
Ahn, J.,Bones, J.,Yu, Y. Q.,Rudd, P. M.,Gilar, M.; 'Separation of 2-aminobenzamide labeled glycans using hydrophilic interaction chromatography columns packed with 1.7 microm sorbent'. J Chromatogr B Analyt Technol Biomed Life Sci, 878 (3-43-4):403-8403. Available Online [Details]
Artemenko, N. V.,Campbell, M. P.,Rudd, P. M.; 'GlycoExtractor: a web-based interface for high throughput processing of HPLC-glycan data'. J Proteome Res, 9 (44):2037-412037. Available Online [Details]
Barrabes, S.,Sarrats, A.,Fort, E.,De Llorens, R.,Rudd, P. M.,Peracaula, R.; 'Effect of sialic acid content on glycoprotein pI analyzed by two-dimensional electrophoresis'. Electrophoresis, . Available Online [Details]
Harvey, D. J.,Jaeken, J.,Butler, M.,Armitage, A. J.,Rudd, P. M.,Dwek, R. A.; 'Fragmentation of negative ions from N-linked carbohydrates, part 4. Fragmentation of complex glycans lacking substitution on the 6-antenna'. J Mass Spectrom, 45 (55):528-35528. Available Online [Details]
Ercan, A.,Cui, J.,Chatterton, D. E.,Deane, K. D.,Hazen, M. M.,Brintnell, W.,O'Donnell, C. I.,Derber, L. A.,Weinblatt, M. E.,Shadick, N. A.,Bell, D. A.,Cairns, E.,Solomon, D. H.,Holers, V. M.,Rudd, P. M.,Lee, D. M.; 'Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis'. Arthritis Rheum, 62 (88):2239-482239. Available Online [Details]
Coman, D. J.,Murray, D. W.,Byrne, J. C.,Rudd, P. M.,Bagaglia, P. M.,Doran, P. D.,Treacy, E. P.; 'Galactosemia, a single gene disorder with epigenetic consequences'. Pediatr Res, 67 (33):286-92286. Available Online [Details]
Harvey, D. J.,Rudd, P. M.; 'Identification of by-products formed during the release of N-glycans with protein N-glycosidase F in the presence of dithiothreitol'. J Mass Spectrom, 45 (77):815-9815. Available Online [Details]
Lauc, G.,Rudan, I.,Campbell, H.,Rudd, P. M.; 'Complex genetic regulation of protein glycosylation'. Mol Biosyst, 6 (22):329-35329. Available Online [Details]
Marino, K.,Bones, J.,Kattla, J. J.,Rudd, P. M.; 'A systematic approach to protein glycosylation analysis: a path through the maze'. Nat Chem Biol, 6 (1010):713-23713. Available Online [Details]
Sarrats, A.,Saldova, R.,Comet, J.,O'Donoghue, N.,de Llorens, R.,Rudd, P. M.,Peracaula, R.; 'Glycan Characterization of PSA 2-DE Subforms from Serum and Seminal Plasma'. OMICS, 14 (44):465-74465. Available Online [Details]
Saldova, R.,Fan, Y.,Fitzpatrick, J. M.,Watson, R. W.,Rudd, P. M.; 'Core fucosylation and {alpha}2-3 sialylation in serum N-glycome is significantly increased in prostate cancer comparing to benign prostate hyperplasia'. Glycobiology, . Available Online [Details]
Ritchie, G.,Harvey, D. J.,Stroeher, U.,Feldmann, F.,Feldmann, H.,Wahl-Jensen, V.,Royle, L.,Dwek, R. A.,Rudd, P. M.; 'Identification of N-glycans from Ebola virus glycoproteins by matrix-assisted laser desorption/ionisation time-of-flight and negative ion electrospray tandem mass spectrometry'. Rapid Commun Mass Spectrom, 24 (55):571-85571. Available Online [Details]
Ritchie, G.,Harvey, D. J.,Feldmann, F.,Stroeher, U.,Feldmann, H.,Royle, L.,Dwek, R. A.,Rudd, P. M.; 'Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein'. Virology, 399 (22):257-69257. Available Online [Details]
Pucic, M.,Pinto, S.,Novokmet, M.,Knezevic, A.,Gornik, O.,Polasek, O.,Vlahovicek, K.,Wang, W.,Rudd, P. M.,Wright, A. F.,Campbell, H.,Rudan, I.,Lauc, G.; 'Common aberrations from the normal human plasma N-glycan profile'. Glycobiology, 20 (88):970-5970. Available Online [Details]
Pierce, A.,Saldova, R.,Abd Hamid, U. M.,Abrahams, J. L.,McDermott, E. W.,Evoy, D.,Duffy, M. J.,Rudd, P. M.; 'Levels of specific glycans significantly distinguish lymph node-positive from lymph node-negative breast cancer patients'. Glycobiology, 20 (1010):1283-81283. Available Online [Details]
Muindi, K.,Cernadas, M.,Watts, G. F.,Royle, L.,Neville, D. C.,Dwek, R. A.,Besra, G. S.,Rudd, P. M.,Butters, T. D.,Brenner, M. B.; 'Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected]'. Proc Natl Acad Sci U S A, 107 (77):3052-73052. Available Online [Details]
Montesino, R.,Gil, J.,Gonzalez, L. J.,Zamora, Y.,Royle, L.,Rudd, P. M.,Dwek, R. A.,Harvey, D. J.,Cremata, J. A.; 'The N-glycosylation of classical swine fever virus E2 glycoprotein extracellular domain expressed in the milk of goat'. Arch Biochem Biophys, 500 (22):169-80169. Available Online [Details]
McVicar, C. M.,Colhoun, L. M.,Abrahams, J. L.,Kitson, C. L.,Hamilton, R.,Medina, R. J.,Durga, D.,Gardiner, T. A.,Rudd, P. M.,Stitt, A. W.; 'Differential modulation of angiogenesis by erythropoiesis-stimulating agents in a mouse model of ischaemic retinopathy'. PLoS One, 5 (77). Available Online [Details]
Triguero, A.,Cabrera, G.,Royle, L.,Harvey, D. J.,Rudd, P. M.,Dwek, R. A.,Bardor, M.,Lerouge, P.,Cremata, J. A.; 'Chemical and enzymatic N-glycan release comparison for N-glycan profiling of monoclonal antibodies expressed in plants'. Anal Biochem, 400 (22):173-83173. Available Online [Details]
Tharmalingam, T.,Marino, K.,Rudd, P. M.; 'Platform technology to identify potential disease markers and establish heritability and environmental determinants of the human serum N-glycome'. Carbohydr Res, 345 (1010):1280-21280. Available Online [Details]
Stanta, J. L.,Saldova, R.,Struwe, W. B.,Byrne, J. C.,Leweke, F. M.,Rothermund, M.,Rahmoune, H.,Levin, Y.,Guest, P. C.,Bahn, S.,Rudd, P. M.; 'Identification of N-glycosylation changes in the CSF and serum in patients with schizophrenia'. J Proteome Res, 9 (99):4476-894476. Available Online [Details]
Liu, L.,Telford, J. E.,Knezevic, A.,Rudd, P. M.; 'High-throughput glycoanalytical technology for systems glycobiology'. Biochem Soc Trans, 38 (55):1374-71374. Available Online [Details]
Knezevic, A.,Gornik, O.,Polasek, O.,Pucic, M.,Redzic, I.,Novokmet, M.,Rudd, P. M.,Wright, A. F.,Campbell, H.,Rudan, I.,Lauc, G.; 'Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans'. Glycobiology, 20 (88):959-69959. Available Online [Details]
Coman DJ, Murray DW, Byrne JC, Rudd PM, Bagaglia PM, Doran PD, Treacy EP; (2010) 'Galactosemia, a Single Gene Disorder With Epigenetic Consequences'. Pediatric Research, 67 (3):286-292. Available Online [Details]
Sarrats, A,Saldova, R,Pla, E,Fort, E,Harvey, DJ,Struwe, WB,de Llorens, R,Rudd, PM,Peracaula, R; (2010) 'Glycosylation of liver acute-phase proteins in pancreatic cancer and chronic pancreatitis'. Proteomics, 4 (4):432-448. Available Online [DOI] [Details]
Artemenko, NV,Campbell, MP,Rudd, PM; (2010) 'GlycoExtractor: A Web-Based Interface for High Throughput Processing of HPLC-Glycan Data'. Journal of Proteome Research, 9 (4):2037-2041. Available Online [DOI] [Details]
Montesino, R.,Gil, J.,Gonzalez, L. J.,Zamora, Y.,Royle, L.,Rudd, P. M.,Dwek, R. A.,Harvey, D. J.,Cremata, J. A.; (2010) 'The N-glycosylation of classical swine fever virus E2 glycoprotein extracellular domain expressed in the milk of goat'. Arch Biochem Biophys, 500 (2):169-180. Available Online [Details]
Triguero, A,Cabrera, G,Royle, L,Harvey, DJ,Rudd, PM,Dwek, RA,Bardor, M,Lerouge, P,Cremata, JA; (2010) 'Chemical and enzymatic N-glycan release comparison for N-glycan profiling of monoclonal antibodies expressed in plants'. Analytical Biochemistry, 400 (2):173-183. Available Online [DOI] [Details]
Ritchie, G,Harvey, DJ,Feldmann, F,Stroeher, U,Feldmann, H,Royle, L,Dwek, RA,Rudd, PM; (2010) 'Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein'. Virology, 399 (2):257-269. Available Online [DOI] [Details]
Harvey, DJ,Jaeken, J,Butler, M,Armitage, AJ,Rudd, PM,Dwek, RA; (2010) 'Fragmentation of negative ions from N-linked carbohydrates, Part 4. Fragmentation of complex glycans lacking substitution on the 6-antenna'. Journal Of Mass Spectrometry, 45 (5):528-535. Available Online [DOI] [Details]
Ritchie, G,Harvey, DJ,Stroeher, U,Feldmann, F,Feldmann, H,Wahl-Jensen, V,Royle, L,Dwek, RA,Rudd, PM; (2010) 'Identification of N-glycans from Ebola virus glycoproteins by matrix-assisted laser desorption/ionisation time-of-flight and negative ion electrospray tandem mass spectrometry'. Rapid Communications in Mass Spectrometry, 24 (5):571-585. Available Online [DOI] [Details]
Ahn, J,Bones, J,Yu, YQ,Rudd, PM,Gilar, M; (2010) 'Separation of 2-aminobenzamide labeled glycans using hydrophilic interaction chromatography columns packed with 1.7 mu m sorbent'. J Chromatography B, 878 (3-4):403-408. [DOI] [Details]
Jimenez-Dalmaroni, M. J.,Xiao, N.,Corper, A. L.,Verdino, P.,Ainge, G. D.,Larsen, D. S.,Painter, G. F.,Rudd, P. M.,Dwek, R. A.,Hoebe, K.,Beutler, B.,Wilson, I. A.; (2009) 'Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2'. PLoS One, 4 (10):e7411-1-e7411-12. Available Online [Details]
Mackeen, M. M.,Almond, A.,Deschamps, M.,Cumpstey, I.,Fairbanks, A. J.,Tsang, C.,Rudd, P. M.,Butters, T. D.,Dwek, R. A.,Wormald, M. R.; (2009) 'The conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway'. J Mol Biol, 387 (22):335-347. Available Online [Details]
Taniguchi, N.,Hancock, W.,Lubman, D. M.,Rudd, P. M.; (2009) 'The second golden age of glycomics: from functional glycomics to clinical applications'. Journal of Proteome Research, 8 (22):425-426. Available Online [Details]
Knezevic, A,Polasek, O,Gornik, O,Rudan, I,Campbell, H,Hayward, C,Wright, A,Kolcic, I,O'Donoghue, N,Bones, J,Rudd, PM,Lauc, G; (2009) 'Variability, Heritability and Environmental Determinants of Human Plasma N-Glycome'. Journal of Proteome Research, 8 (2):694-701. Available Online [DOI] [Details]
Harvey, DJ,Crispin, M,Moffatt, BE,Smith, SL,Sim, RB,Rudd, PM,Dwek, RA; (2009) 'Identification of high-mannose and multiantennary complex-type N-linked glycans containing alpha-galactose epitopes from Nurse shark IgM heavy chain'. Glycoconjugate journal, 26 (8):1055-1064. Available Online [DOI] [Details]
Harvey, DJ,Merry, AH,Royle, L,Campbell, MP,Dwek, RA,Rudd, PM; (2009) 'Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds'. Proteomics, 9 (15):3796-3801. Available Online [DOI] [Details]
Montesino, R,Toledo, JR,Sanchez, B,Zamora, Y,Barrera, M,Royle, L,Rudd, PM,Dwek, RA,Harvey, DJ,Cremata, JA; (2009) 'N-Glycosylation Pattern of E2 Glycoprotein from Classical Swine Fever Virus'. Journal of Proteome Research, 8 (2):546-555. Available Online [DOI] [Details]
Rudd, P. M.,Rudan, I.,Wright, A. F.; (2009) 'High-throughput glycome analysis is set to join high-throughput genomics'. Journal of Proteome Research, 8 (3):1105-1105. Available Online [Details]
Su, Y.,Royle, L.,Radcliffe, C. M.,Harvey, D. J.,Dwek, R. A.,Martinez-Pomares, L.,Rudd, P. M.; (2009) 'Detailed N-glycan analysis of mannose receptor purified from murine spleen indicates tissue specific sialylation'. Biochem Biophys Res Commun, 384 (4):436-443. Available Online [Details]
Montesino, R,Toledo, JR,Sanchez, O,Sanchez, A,Harvey, DJ,Royle, L,Dwek, RA,Rudd, PM,Gerwig, GJ,Kamerling, JP,Cremata, JA; (2008) 'Monosialylated biantennary N-glycoforms containing GalNAc-GlcNAc antennae predominate when human EPO is expressed in goat milk'. Archives of Biochemistry and Biophysics, 470 (2):163-175. Available Online [DOI] [Details]
Banda, NK,Wood, AK,Takahashi, K,Levitt, B,Rudd, PM,Royle, L,Abrahams, JL,Stahl, GL,Holers, VM,Arend, WP; (2008) 'Initiation of the Alternative Pathway of Murine Complement by Immune Complexes Is Dependent on N-Glycans in IgG Antibodies'. Arthritis and Rheumatism, 58 (10):3081-3089. Available Online [DOI] [Details]
Peracaula, R,Barrabes, S,Sarrats, A,Rudd, PM,de Llorens, R; (2008) 'Altered glycosylation in tumours focused to cancer diagnosis'. Disease Markers, 25 (4-5):207-218. Available Online [Details]
Tamguney, G.,Giles, K.,Glidden, D. V.,Lessard, P.,Wille, H.,Tremblay, P.,Groth, D. F.,Yehiely, F.,Korth, C.,Moore, R. C.,Tatzelt, J.,Rubinstein, E.,Boucheix, C.,Yang, X.,Stanley, P.,Lisanti, M. P.,Dwek, R. A.,Rudd, P. M.,Moskovitz, J.,Epstein, C. J.,Cruz, T. D.,Kuziel, W. A.,Maeda, N.,Sap, J.,Ashe, K. H.,Carlson, G. A.,Tesseur, I.,Wyss-Coray, T.,Mucke, L.,Weisgraber, K. H.,Mahley, R. W.,Cohen, F. E.,Prusiner, S. B.; (2008) 'Genes contributing to prion pathogenesis'. Journal of General Virology, 89 (Pt 7):1777-1788. Available Online [Details]
Storr, S. J.,Royle, L.,Chapman, C. J.,Hamid, U. M.,Robertson, J. F.,Murray, A.,Dwek, R. A.,Rudd, P. M.; (2008) 'The O-linked glycosylation of secretory/shed MUC1 from an advanced breast cancer patient's serum'. Glycobiology, 18 (6):456-462. Available Online [Details]
Seveno, M.,Cabrera, G.,Triguero, A.,Burel, C.,Leprince, J.,Rihouey, C.,Vezina, L. P.,D'Aoust, M. A.,Rudd, P. M.,Royle, L.,Dwek, R. A.,Harvey, D. J.,Lerouge, P.,Cremata, J. A.,Bardor, M.; (2008) 'Plant N-glycan profiling of minute amounts of material'. Anal Biochem, 379 (1):66-72. Available Online [Details]
Saldova, R.,Wormald, M. R.,Dwek, R. A.,Rudd, P. M.; (2008) 'Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease pathogenesis'. Disease Markers, 25 (4-5):219-232. Available Online [Details]
Kim, Y. G.,Shin, D. S.,Yang, Y. H.,Gil, G. C.,Park, C. G.,Mimura, Y.,Cooper, D. K.,Rudd, P. M.,Dwek, R. A.,Lee, Y. S.,Kim, B. G.; (2008) 'High-throughput screening of glycan-binding proteins using miniature pig kidney N-glycan-immobilized beads'. Chemistry & Biology, 15 (3):215-223. Available Online [DOI] [Details]
Campbell, M. P.,Royle, L.,Radcliffe, C. M.,Dwek, R. A.,Rudd, P. M.; (2008) 'GlycoBase and autoGU: tools for HPLC-based glycan analysis'. Bioinformatics, 24 (9):1214-1216. Available Online [Details]
Brooks, S. A.,Carter, T. M.,Royle, L.,Harvey, D. J.,Fry, S. A.,Kinch, C.,Dwek, R. A.,Rudd, P. M.; (2008) 'Altered glycosylation of proteins in cancer: what is the potential for new anti-tumour strategies'. Anti-Cancer Agents in Medicinal Chemistry, 8 (1):2-21. Available Online [Details]
Boland, M.,Rudd, P. M.; (2008) 'Disease related glycosylation changes and biomarker discovery: challenges and possibilities in an emerging field. Editorial'. Disease Markers, 25 (4-5):189-192. Available Online [Details]
Arnold, J. N.,Saldova, R.,Hamid, U. M.,Rudd, P. M.; (2008) 'Evaluation of the serum N-linked glycome for the diagnosis of cancer and chronic inflammation'. Proteomics, 8 (16):3284-3293. Available Online [Details]
Abd Hamid, U. M.,Royle, L.,Saldova, R.,Radcliffe, C. M.,Harvey, D. J.,Storr, S. J.,Pardo, M.,Antrobus, R.,Chapman, C. J.,Zitzmann, N.,Robertson, J. F.,Dwek, R. A.,Rudd, P. M.; (2008) 'A strategy to reveal potential glycan markers from serum glycoproteins associated with breast cancer progression'. Glycobiology, 18 (12):1105-1118. Available Online [Details]
Saldova, R,Royle, L,Radcliffe, CM,Hamid, UMA,Evans, R,Arnold, JN,Banks, RE,Hutson, R,Harvey, DJ,Antrobus, R,Petrescu, SM,Dwek, RA,Rudd, PM; (2007) 'Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG'. Glycobiology, 17 (12):1344-1356. Available Online [DOI] [Details]
Gornik, O,Royle, L,Harvey, DJ,Radcliffe, CM,Saldova, R,Dwek, RA,Rudd, P,Lauc, G; (2007) 'Changes of serum glycans during sepsis and acute pancreatitis'. Glycobiology, 17 (12):1321-1332. Available Online [DOI] [Details]
Wada, Y,Azadi, P,Costello, CE,Dell, A,Dwek, RA,Geyer, H,Geyer, R,Kakehi, K,Karlsson, NG,Kato, K,Kawasaki, N,Khoo, KH,Kim, S,Kondo, A,Lattova, E,Mechref, Y,Miyoshi, E,Nakamura, K,Narimatsu, H,Novotny, MV,Packer, NH,Perreault, H,Peter-Katalinic, J,Pohlentz, G,Reinhold, VN,Rudd, PM,Suzuki, A,Taniguchi, N; (2007) 'Comparison of the methods for profiling glycoprotein glycans - HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study'. Glycobiology, 17 (4):411-422. Available Online [DOI] [Details]
Harvey DJ, Royle L, Radcliffe CM, Rudd PM, Dwek RA; (2008) 'Structural and quantitative analysis of N-linked glycans by matrix-assisted laser desorption ionization and negative ion nanospray mass spectrometry'. Analytical Biochemistry, 376 (1):44-60. [DOI] [Details]
Harvey DJ, Crispin M, Scanlan C, Singer BB, Lucka L, Chang VT, Radcliffe CM, Thobhani S, Yuen CT, Rudd PM; (2008) 'Differentiation between isomeric triantennary N-linked glycans by negative ion tandem mass spectrometry and confirmation of glycans containing galactose attached to the bisecting (beta1-4-GlcNAc) residue in N-glycans from IgG'. Rapid Communications in Mass Spectrometry, 22 (7):1047-1052. Available Online [DOI] [Details]
Royle L, Matthews E, Corfield A, Berry M, Rudd PM, Dwek RA, Carrington SD; (2008) 'Glycan structures of ocular surface mucins in man, rabbit and dog display species differences'. Glycoconjugate journal, 25 (8):763-773. Available Online [DOI] [Details]
Gordon S, Miller JL, deWet BJ, Martinez-Pomares L, Radcliffe CM, Dwek RA, Rudd PM, ; (2008) 'The mannose receptor mediates dengue virus infection of macrophages'. PLoS pathogens, 4 (2):e17-1-e17-11. Available Online [DOI] [Details]
Royle L, Campbell MP, Radcliffe CM, White DM, Harvey DJ, Abrahams JL, Kim YG, Henry GW, Shadick NA, Weinblatt ME, Lee DM, Rudd PM, Dwek RA; (2008) 'HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software'. Analytical Biochemistry, 376 (1):1-12. Available Online [DOI] [Details]
McCann KJ, Ottensmeier CH, Callard A, Radcliffe CM, Harvey DJ, Dwek RA, Rudd PM, Sutton BJ, Hobby P, Stevenson FK; (2008) 'Remarkable selective glycosylation of the immunoglobulin variable region in follicular lymphoma'. Molecular immunology, 45 (6):1567-1572. [DOI] [Details]
Domann Dr. PJ, Pardos-Pardos AC, Fernandes DL, Spencer DIR, Radcliffe CM, Royle L, Dwek RA, Rudd PM; (2007) 'Separation-based glycoprofiling approaches using fluorescent labels'. Proteomics, 7 (Suppl 1):70-76. Available Online [DOI] [Details]
Scanlan CN, Ritchie GE, Baruah K, Crispin M, Harvey DJ, Singer BB, Lucka L, Wormald MR, Wentworth P Jr, Zitzmann N, Rudd PM, Burton DR, Dwek RA; (2007) 'Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody'. Journal of Molecular Biology, 372 (1):16-22. Available Online [DOI] [Details]
Sanchez O, Montesino R, Toledo JR, Rodriguez E, Diaz D, Royle L, Rudd PM, Dwek RA, Gerwig GJ, Kamerling JP, Harvey DJ, Cremata JA; (2007) 'The goat mammary glandular epithelial (GMGE) cell line promotes polyfucosylation and N,N'-diacetyllactosediaminylation of N-glycans linked to recombinant human erythropoietin'. Archives of Biochemistry and Biophysics, 464 (2):322-334. Available Online [DOI] [Details]
Mimura Y, Mimura-Kimura Y, Doores K, Golgher D, Davis BG, Dwek RA, Rudd PM, Elliott T; (2007) 'Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing'. Proceedings of the National Academy of Sciences of the United States of America, 104 (14):5983-5988. Available Online [DOI] [Details]
Peracaula R, Barrabés S, Pagès-Pons L, Radcliffe CM, Tabarés G, Fort E, Royle L, Harvey DJ, Moenner M, Dwek RA, Rudd PM, De Llorens R, ; (2007) 'Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer'. Glycobiology, 17 (4):388-400. [DOI] [Details]
Radcliffe CM, Arnold JN, Suter DM, Wormald MR, Harvey DJ, Royle L, Mimura Y, Kimura Y, Sim RB, Inoges S, Rodriguez-Calvillo M, Zabalegui N, de Cerio ALD, Potter KN, Mockridge CI, Dwek RA, Bendandi M, Rudd PM, Stevenson FK; (2007) 'Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor'. Journal of Biological Chemistry, 282 (10):7405-7415. Available Online [DOI] [Details]
Robijn ML, Koeleman CA, Wuhrer M, Royle L, Geyer R, Dwek RA, Rudd PM, Deelder AM, Hokke CH; (2007) 'Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody'. Molecular and Biochemical Parasitology, 151 (2):148-161. Available Online [DOI] [Details]
Dwek RA, Arnold JN, Wormald MR, Sim RB, Rudd PM, ; (2007) 'The impact of glycosylation on the biological function and structure of human immunoglobulins'. Annual review of immunology, 25 :21-50. Available Online [DOI] [Details]
Rudd PM, Harvey DJ, Dwek RA, ; (2006) 'Determining the structure of glycan moieties by mass spectrometry'. Protein Science, Chapter 12 . [DOI] [Details]
Rudd PM, Royle L, Dwek RA, ; (2006) 'Determining the structure of oligosaccharides N- and O-linked to glycoproteins'. Protein Science, Chapter 12 . [DOI] [Details]
Fry SA, Van den Steen PE, Royle L, Wormald MR, Leathem AJ, Opdenakker G, McDonnell JM, Dwek RA, Rudd PM ; (2006) 'Cancer-associated glycoforms of gelatinase B exhibit a decreased level of binding to galectin-3'. Biochemistry, 45 (51):15249-15258. Available Online [DOI] [Details]
Rudd PM, Omtvedt LA, Royle L, Husby G, Sletten K, Radcliffe CM, Harvey DJ, Dwek RA, ; (2006) 'Glycan analysis of monoclonal antibodies secreted in deposition disorders indicates that subsets of plasma cells differentially process IgG glycans'. Arthritis and Rheumatism, 54 (11):3433-3440. [DOI] [Details]
Rudd PM, Royle L, Radcliffe CM, Dwek RA, ; (2006) 'Detailed structural analysis of N-glycans released from glycoproteins in SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions'. Methods in molecular biology (Clifton, N.J.), 347 :125-143. [DOI] [Details]
Sim RB, Tsiftsoglou SA, Arnold JN, Roversi P, Crispin MD, Radcliffe C, Lea SM, Dwek RA, Rudd PM, ; (2006) 'Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides'. 1764 (11):1757-1766. [DOI] [Details]
van Kooten C, Oortwijn BD, Roos A, Royle L, van Gijlswijk-Janssen DJ, Faber-Krol MC, Eijgenraam JW, Dwek RA, Daha MR, Rudd PM, ; (2006) 'Differential glycosylation of polymeric and monomeric IgA: a possible role in glomerular inflammation in IgA nephropathy'. Journal of the American Society of Nephrology, 17 (12):3529-3539. [DOI] [Details]
Lerouge P, Bardor M, Cabrera G, Rudd PM, Dwek RA, Cremata JA, ; (2006) 'Analytical strategies to investigate plant N-glycan profiles in the context of plant-made pharmaceuticals'. Current Opinion in Structural Biology, 16 (5):576-583. [DOI] [Details]
Karande AA, Jayachandran R, Radcliffe CM, Royle L, Harvey DJ, Dwek RA, Rudd PM, ; (2006) 'Oligosaccharides modulate the apoptotic activity of glycodelin'. Glycobiology, 16 (11):1052-1063. [DOI] [Details]
Rudd PM, Webber D, Radcliffe CM, Royle L, Tobiasen G, Merry AH, Rodgers AL, Sturrock ED, Wormald MR, Harvey DJ, Dwek RA, ; (2006) 'Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation'. FEBS Journal, 273 (13):3024-3037. [DOI] [Details]
Sim RB, Arnold JN, Dwek RA, Rudd PM, ; (2006) 'Mannan binding lectin and its interaction with immunoglobulins in health and in disease'. IMMUNOLOGY LETTERS, 106 (2):103-110. [DOI] [Details]
Wopereis S, Abd Hamid UM, Critchley A, Royle L, Dwek RA, Morava E, Leroy JG, Wilcken B, Lagerwerf AJ, Huijben KM, Lefeber DJ, Rudd PM, Wevers RA; (2006) 'Abnormal glycosylation with hypersialylated O-glycans in patients with Sialuria'. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1762 (6):598-607. Available Online [DOI] [Details]
Dewerchin M, Jacquemin M, Radcliffe CM, Lavend'homme R, Wormald MR, Vanderelst L, Wallays G, Dewaele J, Collen D, Vermylen J, Dwek RA, Saint-Remy JM, Rudd PM, ; (2006) 'Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody'. Journal of Thrombosis and Haemostasis, 4 (5):1047-1055. [DOI] [Details]
Rudd PM, Crispin M, Harvey DJ, Chang VT, Yu C, Aricescu AR, Jones EY, Davis SJ, Dwek RA, ; (2006) 'Inhibition of hybrid- and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway'. Glycobiology, 16 (8):748-756. [DOI] [Details]
Opdenakker G, Van den Steen PE, Van Aelst I, Hvidberg V, Piccard H, Fiten P, Jacobsen C, Moestrup SK, Fry S, Royle L, Wormald MR, Wallis R, Rudd PM, Dwek RA, ; (2006) 'The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors'. Journal of Biological Chemistry, 281 (27):18626-18637. [DOI] [Details]
Davis BG, Doores KJ, Mimura Y, Dwek RA, Rudd PM, Elliott T, ; (2006) 'Direct deprotected glycosyl-asparagine ligation'. Chemical Communications, (13):1401-1403. [DOI] [Details]
Wilson IA, Shore DA, Teyton L, Dwek RA, Rudd PM, ; (2006) 'Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution'. Journal of Molecular Biology, 358 (2):347-354. [DOI] [Details]
Kim BG, Kim YG, Kim SY, Hur YM, Joo HS, Chung J, Lee DS, Royle L, Rudd PM, Dwek RA, Harvey DJ, ; (2006) 'The identification and characterization of xenoantigenic nonhuman carbohydrate sequences in membrane proteins from porcine kidney'. Proteomics, 6 (4):1133-1142. [DOI] [Details]
Dwek RA, Opdenakker G, Dillen C, Fiten P, Martens E, Van Aelst I, Van den Steen PE, Nelissen I, Starckx S, Descamps FJ, Hu J, Piccard H, Van Damme J, Wormald MR, Rudd PM, ; (2006) 'Remnant epitopes, autoimmunity and glycosylation'. 1760 (4):610-615. [DOI] [Details]
Sim RB, Arnold JN, Wallis R, Willis AC, Harvey DJ, Royle L, Dwek RA, Rudd PM, ; (2006) 'Interaction of mannan binding lectin with alpha2 macroglobulin via exposed oligomannose glycans: a conserved feature of the thiol ester protein family?'. Journal of Biological Chemistry, 281 (11):6955-6963. [DOI] [Details]
de Llorens R, Tabarés G, Radcliffe CM, Barrabés S, Ramírez M, Aleixandre RN, Hoesel W, Dwek RA, Rudd PM, Peracaula R, ; (2006) 'Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA'. Glycobiology, 16 (2):132-145. [DOI] [Details]
Dwek RA, Fry SA, Van den Steen PE, Royle L, Wormald MR, Leathem AJ, Opdenakker G, Rudd PM, ; (2005) 'Differential glycosylation of gelatinase B from neutrophils and breast cancer cells'. Frontiers in Modeling and Control of Breathing, 564 :103-112. [Details]
Elliott T, Mimura Y, Golgher D, Mimura-Kimura Y, Dwek RA, Rudd PM, ; (2005) 'Immunogenicity of calreticulin-bound murine leukemia virus glycoprotein gp90'. Frontiers in Modeling and Control of Breathing, 564 :85-94. [Details]
Rudd PM, Shore DA, Wilson IA, Dwek RA, ; (2005) 'Glycosylation and the function of the T cell co-receptor CD8'. Frontiers in Modeling and Control of Breathing, 564 :71-84. [Details]
Sim RB, Arnold JN, Royle L, Dwek RA, Rudd PM, ; (2005) 'Human immunoglobulin glycosylation and the lectin pathway of complement activation'. Frontiers in Modeling and Control of Breathing, 564 :27-43. [Details]
Rudd PM, Su YR, Tsang C, Bakker T, Harris J, Gordon S, Dwek RA, Martinez-Pomares L, ; (2005) 'Glycosylation influences the ligand binding activities of mannose receptor'. Frontiers in Modeling and Control of Breathing, 564 :25-26. [Details]
Martinez-Pomares L, Su Y, Bakker T, Harris J, Tsang C, Brown GD, Wormald MR, Gordon S, Dwek RA, Rudd PM, ; (2005) 'Glycosylation influences the lectin activities of the macrophage mannose receptor'. Journal of Biological Chemistry, 280 (38):32811-32820. [DOI] [Details]
Sim RB, Arnold JN, Wormald MR, Suter DM, Radcliffe CM, Harvey DJ, Dwek RA, Rudd PM, ; (2005) 'Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin'. Journal of Biological Chemistry, 280 (32):29080-29087. [DOI] [Details]
Dieplinger H, Jerkovic L, Voegele AF, Chwatal S, Kronenberg F, Radcliffe CM, Wormald MR, Lobentanz EM, Ezeh B, Eller P, Dejori N, Dieplinger B, Lottspeich F, Sattler W, Uhr M, Mechtler K, Dwek RA, Rudd PM, Baier G, ; (2005) 'Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression'. Journal of Proteome Research, 4 (3):889-899. [DOI] [Details]
Watt SM, Jorgensen-Tye B, Levesque JP, Royle L, Doyonnas R, Chan JY, Dwek RA, Rudd PM, Harvey DJ, Simmons PJ, ; (2005) 'Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis'. Tissue antigens, 65 (3):220-239. [DOI] [Details]
Wilson IA, Zajonc DM, Crispin MD, Bowden TA, Young DC, Cheng TY, Hu J, Costello CE, Rudd PM, Dwek RA, Miller MJ, Brenner MB, Moody DB, ; (2005) 'Molecular mechanism of lipopeptide presentation by CD1a'. Immunity, 22 (2):209-219. [DOI] [Details]
Rudd PM, Arnold JN, Radcliffe CM, Wormald MR, Royle L, Harvey DJ, Crispin M, Dwek RA, Sim RB, ; (2004) 'The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin'. Immunology, 173 (11):6831-6840. [Details]
Downing AK, O'Leary JM, Radcliffe CM, Willis AC, Dwek RA, Rudd PM, ; (2004) 'Identification and removal of O-linked and non-covalently linked sugars from recombinant protein produced using Pichia pastoris'. Protein Expression and Purification, 38 (2):217-227. [DOI] [Details]
Dwek RA, Rudd PM, Wormald MR, ; (2004) 'Sugar-mediated ligand-receptor interactions in the immune system'. Trends in Biotechnology, 22 (10):524-530. [DOI] [Details]
Harvey DJ, Omtvedt LA, Royle L, Husby G, Sletten K, Radcliffe C, Dwek RA, Rudd PM, ; (2004) 'Artefacts formed by addition of urea to N-linked glycans released with peptide-N-glycosidase F for analysis by mass spectrometry'. Rapid communications in mass spectrometry : RCM, 18 (19):2357-2359. [DOI] [Details]
Platt N, Tian G, Wilcockson D, Perry VH, Rudd PM, Dwek RA, Platt FM, ; (2004) 'Inhibition of alpha-glucosidases I and II increases the cell surface expression of functional class A macrophage scavenger receptor (SR-A) by extending its half-life'. Journal of Biological Chemistry, 279 (38):39303-39309. [DOI] [Details]
Khalaila I, Peter-Katalinic J, Tsang C, Radcliffe CM, Aflalo ED, Harvey DJ, Dwek RA, Rudd PM, Sagi A; (2004) 'Structural characterization of the N-glycan moiety and site of glycosylation in vitellogenin from the decapod crustacean Cherax quadricarinatus'. Glycobiology, 14 (9):767-774. Available Online [DOI] [Details]
Rudd PM, Tekoah Y, Ko K, Koprowski H, Harvey DJ, Wormald MR, Dwek RA, ; (2004) 'Controlled glycosylation of therapeutic antibodies in plants'. Archives of Biochemistry and Biophysics, 426 (2):266-278. [DOI] [Details]
Rudd PM, Crispin MD, Ritchie GE, Critchley AJ, Morgan BP, Wilson IA, Dwek RA, Sim RB, ; (2004) 'Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure'. FEBS Letters, 566 (1-3):270-274. [DOI] [Details]
Cresswell P, Wearsch PA, Jakob CA, Vallin A, Dwek RA, Rudd PM, ; (2004) 'Major histocompatibility complex class I molecules expressed with monoglucosylated N-linked glycans bind calreticulin independently of their assembly status'. Journal of Biological Chemistry, 279 (24):25112-25121. [DOI] [Details]
Wong CH, Lee HK, Scanlan CN, Huang CY, Chang AY, Calarese DA, Dwek RA, Rudd PM, Burton DR, Wilson IA, ; (2004) 'Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody'. Angewandte Chemie (International ed. in English), 43 (8):1000-1003. [DOI] [Details]
Lea SM, Lukacik P, Roversi P, White J, Esser D, Smith GP, Billington J, Williams PA, Rudd PM, Wormald MR, Harvey DJ, Crispin MD, Radcliffe CM, Dwek RA, Evans DJ, Morgan BP, Smith RA, ; (2004) 'Complement regulation at the molecular level: the structure of decay-accelerating factor'. Proceedings of the National Academy of Sciences of the United States of America, 101 (5):1279-1284. [DOI] [Details]
Rudd PM, Scanlan CN, Pantophlet R, Wormald MR, Saphire EO, Calarese D, Stanfield R, Wilson IA, Katinger H, Dwek RA, Burton DR, ; (2003) 'The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12'. Frontiers in Modeling and Control of Breathing, 535 :205-218. [Details]
Wilson IA, Saphire EO, Stanfield RL, Crispin MD, Morris G, Zwick MB, Pantophlet RA, Parren PW, Rudd PM, Dwek RA, Burton DR, ; (2003) 'Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design'. Frontiers in Modeling and Control of Breathing, 535 :55-66. [Details]
Wilson IA, Calarese DA, Scanlan CN, Zwick MB, Deechongkit S, Mimura Y, Kunert R, Zhu P, Wormald MR, Stanfield RL, Roux KH, Kelly JW, Rudd PM, Dwek RA, Katinger H, Burton DR, ; (2003) 'Antibody domain exchange is an immunological solution to carbohydrate cluster recognition'. Science, 300 (5628):2065-2071. [DOI] [Details]
Koprowski H, Ko K, Tekoah Y, Rudd PM, Harvey DJ, Dwek RA, Spitsin S, Hanlon CA, Rupprecht C, Dietzschold B, Golovkin M, ; (2003) 'Function and glycosylation of plant-derived antiviral monoclonal antibody'. Proceedings of the National Academy of Sciences of the United States of America, 100 (13):8013-8018. [DOI] [Details]
Rudd PM, Butler M, Quelhas D, Critchley AJ, Carchon H, Hebestreit HF, Hibbert RG, Vilarinho L, Teles E, Matthijs G, Schollen E, Argibay P, Harvey DJ, Dwek RA, Jaeken J, ; (2003) 'Detailed glycan analysis of serum glycoproteins of patients with congenital disorders of glycosylation indicates the specific defective glycan processing step and provides an insight into pathogenesis'. Glycobiology, 13 (9):601-622. [DOI] [Details]
Davis SJ, Merry AH, Gilbert RJ, Shore DA, Royle L, Miroshnychenko O, Vuong M, Wormald MR, Harvey DJ, Dwek RA, Classon BJ, Rudd PM, ; (2003) 'O-glycan sialylation and the structure of the stalk-like region of the T cell co-receptor CD8'. Journal of Biological Chemistry, 278 (29):27119-27128. [DOI] [Details]
Rudd PM, Royle L, Roos A, Harvey DJ, Wormald MR, van Gijlswijk-Janssen D, Redwan el-RM, Wilson IA, Daha MR, Dwek RA, ; (2003) 'Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems'. Journal of Biological Chemistry, 278 (22):20140-20153. [DOI] [Details]
Kim S, Hwang SK, Dwek RA, Rudd PM, Ahn YH, Kim EH, Cheong C, Kim S II, Park NS, Lee SM; (2003) 'Structural determination of the N-glycans of a lepidopteran arylphorin reveals the presence of a monoglucosylated oligosaccharide in the storage protein'. Glycobiology, 13 (3):147-157. Available Online [DOI] [Details]
de Llorens R, Peracaula R, Royle L, Tabares G, Mallorqui-Fernández G, Barrabés S, Harvey DJ, Dwek RA, Rudd PM, ; (2003) 'Glycosylation of human pancreatic ribonuclease: differences between normal and tumor states'. Glycobiology, 13 (4):227-244. [DOI] [Details]
de Llorens R, Peracaula R, Tabarés G, Royle L, Harvey DJ, Dwek RA, Rudd PM, ; (2003) 'Altered glycosylation pattern allows the distinction between prostate-specific antigen (PSA) from normal and tumor origins'. Glycobiology, 13 (6):457-470. [DOI] [Details]
Opdenakker G, Van den Steen PE, Dubois B, Nelissen I, Rudd PM, Dwek RA, ; (2002) 'Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9)'. Critical reviews in biochemistry and molecular biology, 37 (6):375-536. [Details]
Dwek RA, Rudd PM, Merry AH, Wormald MR, ; (2002) 'Glycosylation and prion protein'. Current Opinion in Structural Biology, 12 (5):578-586. [Details]
Mariani P, Navazio L, Miuzzo M, Royle L, Baldan B, Varotto S, Merry AH, Harvey DJ, Dwek RA, Rudd PM, ; (2002) 'Monitoring endoplasmic reticulum-to-Golgi traffic of a plant calreticulin by protein glycosylation analysis'. Biochemistry, 41 (48):14141-14149. [Details]
Rudd PM, Radcliffe CM, Diedrich G, Harvey DJ, Dwek RA, Cresswell P, ; (2002) 'Identification of specific glycoforms of major histocompatibility complex class I heavy chains suggests that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57'. Journal of Biological Chemistry, 277 (48):46415-46423. [DOI] [Details]
Burton DR, Scanlan CN, Pantophlet R, Wormald MR, Ollmann Saphire E, Stanfield R, Wilson IA, Katinger H, Dwek RA, Rudd PM, ; (2002) 'The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120'. Virology, 76 (14):7306-7321. [Details]
Wilson IA, Saphire EO, Stanfield RL, Crispin MD, Parren PW, Rudd PM, Dwek RA, Burton DR, ; (2002) 'Contrasting IgG structures reveal extreme asymmetry and flexibility'. Journal of Molecular Biology, 319 (1):9-18. [DOI] [Details]
Harvey DJ, Wheeler SF, Rudd PM, Davis SJ, Dwek RA, ; (2002) 'Comparison of the N-linked glycans from soluble and GPI-anchored CD59 expressed in CHO cells'. Glycobiology, 12 (4):261-271. [Details]
Rudd PM, Merry AH, Neville DC, Royle L, Matthews B, Harvey DJ, Dwek RA, ; (2002) 'Recovery of intact 2-aminobenzamide-labeled O-glycans released from glycoproteins by hydrazinolysis'. Analytical Biochemistry, 304 (1):91-99. [DOI] [Details]
Rudd PM, Royle L, Mattu TS, Hart E, Langridge JI, Merry AH, Murphy N, Harvey DJ, Dwek RA, ; (2002) 'An analytical and structural database provides a strategy for sequencing O-glycans from microgram quantities of glycoproteins'. Analytical Biochemistry, 304 (1):70-90. [DOI] [Details]
Rudd PM, Magnadóttir B, Crispin M, Royle L, Colominas C, Harvey DJ, Dwek RA, ; (2002) 'The carbohydrate moiety of serum IgM from Atlantic cod (Gadus morhua L.)'. Fish & shellfish immunology, 12 (3):209-227. [Details]
Rudd PM, Harvey DJ, Mattu TS, Wormald MR, Royle L, Dwek RA, ; (2002) 'Internal residue loss: rearrangements occurring during the fragmentation of carbohydrates derivatized at the reducing terminus'. Analytical Chemistry, 74 (4):734-740. [Details]
Rudd PM, Ritchie GE, Moffatt BE, Sim RB, Morgan BP, Dwek RA, ; (2002) 'Glycosylation and the complement system'. Chemical Reviews, 102 (2):305-31. [Details]
Rudd PM, Van den Steen PE, Opdenakker G, Wormald MR, Dwek RA, ; (2001) 'Matrix remodelling enzymes, the protease cascade and glycosylation'. 1528 (2-3):61-73. [Details]
Dwek RA, Rudd PM, Colominas C, Royle L, Murphy N, Hart E, Merry AH, Hebestreit HF, ; (2001) 'A high-performance liquid chromatography based strategy for rapid, sensitive sequencing of N-linked oligosaccharide modifications to proteins in sodium dodecyl sulphate polyacrylamide electrophoresis gel bands'. Proteomics, 1 (2):285-294. [DOI] [Details]
Rudd PM, Garner B, Harvey DJ, Royle L, Frischmann M, Nigon F, Chapman MJ, ; (2001) 'Characterization of human apolipoprotein B100 oligosaccharides in LDL subfractions derived from normal and hyperlipidemic plasma: deficiency of alpha-N-acetylneuraminyllactosyl-ceramide in light and small dense LDL particles'. Glycobiology, 11 (10):791-802. [Details]
Prusiner SB, Peretz D, Williamson RA, Kaneko K, Vergara J, Leclerc E, Schmitt-Ulms G, Mehlhorn IR, Legname G, Wormald MR, Rudd PM, Dwek RA, Burton DR, ; (2001) 'Antibodies inhibit prion propagation and clear cell cultures of prion infectivity'. Nature, 412 (6848):739-743. [DOI] [Details]
Wilson IA, Saphire EO, Parren PW, Pantophlet R, Zwick MB, Morris GM, Rudd PM, Dwek RA, Stanfield RL, Burton DR, ; (2001) 'Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design'. Science, 293 (5532):1155-1159. [DOI] [Details]
Dwek RA, Rudd PM, Opdenakker G, ; (2001) 'Holistic approaches to glycobiology'. Nature biotechnology, 19 (6):531-532. [DOI] [Details]
Dwek RA, Rudd PM, Wormald MR, Wing DR, Prusiner SB, ; (2001) 'Prion glycoprotein: structure, dynamics, and roles for the sugars'. Biochemistry, 40 (13):3759-3766. [Details]
Thillet J, Garner B, Merry AH, Royle L, Harvey DJ, Rudd PM, ; (2001) 'Structural elucidation of the N- and O-glycans of human apolipoprotein(a): role of o-glycans in conferring protease resistance'. Journal of Biological Chemistry, 276 (25):22200-22208. [DOI] [Details]
Dwek RA, Rudd PM, Elliott T, Cresswell P, Wilson IA, ; (2001) 'Glycosylation and the immune system'. Science, 291 (5512):2370-2376. [Details]
Rudd PM, Mattu TS, Royle L, Langridge J, Wormald MR, Van den Steen PE, Van Damme J, Opdenakker G, Harvey DJ, Dwek RA, ; (2000) 'O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme'. Biochemistry, 39 (51):15695-15704. [Details]
Wood HA, Joshi L, Davis TR, Mattu TS, Rudd PM, Dwek RA, Shuler ML, ; (2000) 'Influence of baculovirus-host cell interactions on complex N-linked glycosylation of a recombinant human protein'. Biotechnology Progress, 16 (4):650-656. [Details]
Ferguson MA, Zitzmann N, Mehlert A, Carrouée S, Rudd PM, ; (2000) 'Protein structure controls the processing of the N-linked oligosaccharides and glycosylphosphatidylinositol glycans of variant surface glycoproteins expressed in bloodstream form Trypanosoma brucei'. Glycobiology, 10 (3):243-249. [Details]
Gleizes PE, Rudd PM, Downing AK, Cadene M, Harvey DJ, Wormald MR, Weir I, Dwek RA, Rifkin DB, ; (2000) 'Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells'. Biochemistry, 39 (7):1596-1603. [Details]
Andersen V, Garred P, Madsen HO, Marquart H, Hansen TM, Sørensen SF, Petersen J, Volck B, Svejgaard A, Graudal NA, Rudd PM, Dwek RA, Sim RB, ; (2000) 'Two edged role of mannose binding lectin in rheumatoid arthritis: a cross sectional study'. Journal of Rheumatology, 27 (1):26-34. [Details]
Dwek RA, Rudd PM, Mattu TS, Zitzmann N, Mehta A, Colominas C, Hart E, Opdenakker G, ; (1999) 'Glycoproteins: rapid sequencing technology for N-linked and GPI anchor glycans'. Gene, 16 :1-21. [Details]
Barclay AN, Devasahayam M, Catalino PD, Rudd PM, Dwek RA, ; (1999) 'The glycan processing and site occupancy of recombinant Thy-1 is markedly affected by the presence of a glycosylphosphatidylinositol anchor'. Glycobiology, 9 (12):1381-1387. [Details]
Dwek RA, Rudd PM, Endo T, Colominas C, Groth D, Wheeler SF, Harvey DJ, Wormald MR, Serban H, Prusiner SB, Kobata A, ; (1999) 'Glycosylation differences between the normal and pathogenic prion protein isoforms'. Proceedings of the National Academy of Sciences of the United States of America, 96 (23):13044-13049. [Details]
Wilson IA, Rudd PM, Wormald MR, Stanfield RL, Huang M, Mattsson N, Speir JA, DiGennaro JA, Fetrow JS, Dwek RA, ; (1999) 'Roles for glycosylation of cell surface receptors involved in cellular immune recognition'. Journal of Molecular Biology, 293 (2):351-366. [DOI] [Details]
Opdenakker G, Rudd PM, Mattu TS, Masure S, Bratt T, Van den Steen PE, Wormald MR, Küster B, Harvey DJ, Borregaard N, Van Damme J, Dwek RA, ; (1999) 'Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin'. Biochemistry, 38 (42):13937-13950. [Details]
Axford JS, Watson M, Rudd PM, Bland M, Dwek RA, ; (1999) 'Sugar printing rheumatic diseases: a potential method for disease differentiation using immunoglobulin G oligosaccharides'. Arthritis and Rheumatism, 42 (8):1682-1690. [DOI] [Details]
Dwek RA, Rudd PM, Wormald MR, Harvey DJ, Devasahayam M, McAlister MS, Brown MH, Davis SJ, Barclay AN, ; (1999) 'Oligosaccharide analysis and molecular modeling of soluble forms of glycoproteins belonging to the Ly-6, scavenger receptor, and immunoglobulin superfamilies expressed in Chinese hamster ovary cells'. Glycobiology, 9 (5):443-458. [Details]
Opdenakker G, Van den Steen P, Rudd PM, Proost P, Martens E, Paemen L, Küster B, van Damme J, Dwek RA, ; (1998) 'Oligosaccharides of recombinant mouse gelatinase B variants'. 1425 (3):587-598. [Details]
Driscoll PC, McAlister MS, Brown MH, Willis AC, Rudd PM, Harvey DJ, Aplin R, Shotton DM, Dwek RA, Barclay AN, ; (1998) 'Structural analysis of the CD5 antigen--expression, disulphide bond analysis and physical characterisation of CD5 scavenger receptor superfamily domain 1'. European Journal of Biochemistry, 257 (1):131-141. [Details]
Dwek RA, Rudd PM, Wormald MR, ; (1998) 'Glycosylation and the immune system'. Journal of protein chemistry, 17 (6). [Details]
Jefferis R, Routier FH, Hounsell EF, Rudd PM, Takahashi N, Bond A, Hay FC, Alavi A, Axford JS, ; (1998) 'Quantitation of the oligosaccharides of human serum IgG from patients with rheumatoid arthritis: a critical evaluation of different methods'. Immunology, 213 (2):113-130. [Details]
Dwek RA, Mehta A, Zitzmann N, Rudd PM, Block TM, ; (1998) 'Alpha-glucosidase inhibitors as potential broad based anti-viral agents'. FEBS Letters, 430 (1-2):17-22. [Details]
Opdenakker G, Van den Steen P, Rudd PM, Dwek RA, ; (1998) 'Concepts and principles of O-linked glycosylation'. Critical reviews in biochemistry and molecular biology, 33 (3):151-208. [Details]
Rudd PM, Roberts DB, Mulvany WJ, Dwek RA, ; (1998) 'Mutant analysis reveals an alternative pathway for N-linked glycosylation in Drosophila melanogaster'. European Journal of Biochemistry, 253 (2):494-498. [Details]
Dwek RA, Rudd PM, Morgan BP, Wormald MR, Harvey DJ, van den Berg CW, Davis SJ, Ferguson MA, ; (1998) 'The glycosylation of the complement regulatory protein, human erythrocyte CD59'. Frontiers in Modeling and Control of Breathing, 435 :153-162. [Details]
Opdenakker G, Van den Steen P, Rudd PM, Dwek RA, Van Damme J, ; (1998) 'Cytokine and protease glycosylation as a regulatory mechanism in inflammation and autoimmunity'. Frontiers in Modeling and Control of Breathing, 435 :133-143. [Details]
Berger EG, Hennet T, Dinter A, Kuhnert P, Mattu TS, Rudd PM, ; (1998) 'Genomic cloning and expression of three murine UDP-galactose: beta-N-acetylglucosamine beta1,3-galactosyltransferase genes'. Journal of Biological Chemistry, 273 (1):58-65. [Details]
Dwek RA, Mattu TS, Pleass RJ, Willis AC, Kilian M, Wormald MR, Lellouch AC, Rudd PM, Woof JM, ; (1998) 'The glycosylation and structure of human serum IgA1, Fab, and Fc regions and the role of N-glycosylation on Fc alpha receptor interactions'. Journal of Biological Chemistry, 273 (4):2260-2272. [Details]
Dwek RA, Mehta A, Rudd PM, Block TM, ; (1997) 'A strategy for anti-viral intervention: the use of alpha-glucosidase inhibitors to prevent chaperone-mediated folding of viral envelope glycoproteins'. Biochemical Society Transactions, 25 (4):1188-1193. [Details]
Dwek RA, Rudd PM, Morgan BP, Wormald MR, Harvey DJ, van den Berg CW, Davis SJ, Ferguson MA, ; (1997) 'Roles for glycosylation in the anti-inflammatory molecule CD59'. Biochemical Society Transactions, 25 (4):1177-1184. [Details]
Dwek RA, Rudd PM, ; (1997) 'Rapid, sensitive sequencing of oligosaccharides from glycoproteins'. Current opinion in biotechnology, 8 (4):488-497. [Details]
Dwek RA, Rudd PM, Guile GR, Küster B, Harvey DJ, Opdenakker G, ; (1997) 'Oligosaccharide sequencing technology'. Nature, 388 (6638):205-207. [DOI] [Details]
Rudd PM, Morgan BP, Wormald MR, Harvey DJ, van den Berg CW, Davis SJ, Ferguson MA, Dwek RA; (1997) 'The glycosylation of the complement regulatory protein, human erythrocyte CD59'. Journal of Biological Chemistry, 272 (11):7229-7244. Available Online [Details]
Dwek RA, Wormald MR, Rudd PM, Harvey DJ, Chang SC, Scragg IG, ; (1997) 'Variations in oligosaccharide-protein interactions in immunoglobulin G determine the site-specific glycosylation profiles and modulate the dynamic motion of the Fc oligosaccharides'. Biochemistry, 36 (6):1370-1380. [DOI] [Details]
Bergeron JJ, Zapun A, Petrescu SM, Rudd PM, Dwek RA, Thomas DY, ; (1997) 'Conformation-independent binding of monoglucosylated ribonuclease B to calnexin'. Cell, 88 (1):29-38. [Details]
Dwek RA, Rudd PM, ; (1997) 'Glycosylation: heterogeneity and the 3D structure of proteins'. Critical reviews in biochemistry and molecular biology, 32 (1):1-100. [Details]
Rudd PM, Iourin O, Mattu TS, Mian N, Keir G, Winchester B, Dwek RA, ; (1996) 'The identification of abnormal glycoforms of serum transferrin in carbohydrate deficient glycoprotein syndrome type I by capillary zone electrophoresis'. Glycoconjugate journal, 13 (6):1031-1042. [Details]
Dwek RA, Guile GR, Rudd PM, Wing DR, Prime SB, ; (1996) 'A rapid high-resolution high-performance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles'. Analytical Biochemistry, 240 (2):210-226. [DOI] [Details]
Dwek RA, Rudd PM, Woods RJ, Wormald MR, Opdenakker G, Downing AK, Campbell ID, ; (1995) 'The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator'. 1248 (1):1-10. [Details]
Van Damme J, Opdenakker G, Rudd PM, Wormald M, Dwek RA, ; (1995) 'Cells regulate the activities of cytokines by glycosylation'. FASEB Journal, 9 (5):453-457. [Details]
Sim RB, Malhotra R, Wormald MR, Rudd PM, Fischer PB, Dwek RA, ; (1995) 'Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein'. Nature Medicine, 1 (3):237-243. [Details]
Rudd PM, Mori K, Dwek RA, Downing AK, Opdenakker G, ; (1995) 'The activation of type 1 and type 2 plasminogen by type I and type II tissue plasminogen activator'. Journal of Biological Chemistry, 270 (7):3261-3267. [Details]
Lehner T, Rudd PM, Fortune F, Patel T, Parekh RB, Dwek RA, ; (1994) 'A human T-cell receptor recognizes 'O'-linked sugars from the hinge region of human IgA1 and IgD'. Immunology, 83 (1):99-106. [Details]
Dwek RA, Field MC, Amatayakul-Chantler S, Rademacher TW, Rudd PM, ; (1994) 'Structural analysis of the N-glycans from human immunoglobulin A1: comparison of normal human serum immunoglobulin A1 with that isolated from patients with rheumatoid arthritis'. Biochemical Journal, 299 ( Pt 1) :261-275. [Details]
Dwek RA, Rudd PM, Joao HC, Coghill E, Fiten P, Saunders MR, Opdenakker G, ; (1994) 'Glycoforms modify the dynamic stability and functional activity of an enzyme'. Biochemistry, 33 (1):17-22. [Details]
Dwek RA, Opdenakker G, Rudd PM, Ponting CP, ; (1993) 'Concepts and principles of glycobiology'. FASEB Journal, 7 (14):1330-1337. [Details]
Dwek RA, Rudd PM, Scragg IG, Coghill E, ; (1992) 'Separation and analysis of the glycoform populations of ribonuclease B using capillary electrophoresis'. Glycoconjugate journal, 9 (2):86-91. [Details]
Dwek RA, Rudd PM, Leatherbarrow RJ, Rademacher TW, ; (1991) 'Diversification of the IgG molecule by oligosaccharides'. Molecular immunology, 28 (12):1369-1378. [Details]
Palmier M, Parekh RB, Dwek RA, Rudd PM, Thomas JR, Rademacher TW, Warren T, Wun TC, Hebert B, Reitz B, ; (1989) 'N-glycosylation and in vitro enzymatic activity of human recombinant tissue plasminogen activator expressed in Chinese hamster ovary cells and a murine cell line'. Biochemistry, 28 (19):7670-7679. [Details]
Rademacher TW, Wittwer AJ, Howard SC, Carr LS, Harakas NK, Feder J, Parekh RB, Rudd PM, Dwek RA, ; (1989) 'Effects of N-glycosylation on in vitro activity of Bowes melanoma and human colon fibroblast derived tissue plasminogen activator'. Biochemistry, 28 (19):7662-7669. [Details]
 

Conference Publications

Tharmalingam T, Li L, Mariño K, Abrahams J1, Doherty M1, Bones J1, O¿Donoghue N, Carrington SD, Rudd PM; (2010) The development of a high throughput system for O-glycan analysis 2010 Annual Meeting of the Society for Glycobiology St Petersburg, FL [Details]
Matthews, E., Royle, L., Gierow, J.P., Corfield, A.P., Berry, M., Rudd P.M., Dwek, R.A., Fitzpatrick, E., Gallagher, M.E., Irwin, J., Reid, C.R., Carrington, S. D.; (2007) New insights into supramucosal gel turnover:The role of mucin glycosylation 8th Jenner Glycobiology and Medicine SymposiumOrganised by the Clinical Immunology and allergy section, Royal Society of Medicine, UK andOxford-Dublin Glycobiology Laboratory, University College Dublin, IrelandO’Reilly Hall, University College Dublin  [Details]
Matthews, E., Royle, L., Gierow, J.P., Corfield, A.P., Berry, M., Rudd P.M., Dwek, R.A., Fitzpatrick, E., Gallagher, M.E., Irwin, J., Reid, C.R. and Carrington, S. D.; (2007) New insights into supramucosal gel turnover: the role of mucin glycosylation Royal Society of Medicine. 8th Jenner Glycobiology and Medicine Symposium. Oct 2007 UCD Dublin Available Online [Details]
   

Editorial

Taniguchi, N,Hancock, W,Lubman, DM,Rudd, PM; (2009) The Second Golden Age of Glycomics: From Functional Glycomics to Clinical Applications. Editorial [DOI] [Details]
Packer, NH,von der Lieth, CW,Aoki-Kinoshita, KF,Lebrilla, CB,Paulson, JC,Raman, R,Rudd, P,Sasisekharan, R,Taniguchi, N,York, WS; (2008) Frontiers in glycomics: Bioinformatics and biomarkers in disease - An NIH White Paper prepared from discussions by the focus groups at a workshop on the NIH campus, Bethesda MD (September 11-13,2006). Editorial [DOI] [Details]