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Researchers at UCD

researcher

Arun Kumar

Director-Stemcology

School of Veterinary Medicine
216, Veterinary Sciences Centre
UCD, Belfield, Dublin 04

Tel: +353 1 7166230
Email:

Biography

Clinician, Drug Discovery Scientist and Entrepreneur with over 15 years of research and teaching experience in pharmacology and regenerative medicine. Extensive international experience with over 100 peer-reviewed publications. I have attracted investments from several national and international organisations at various stages of my carrier. I have successfully directed several projects in preclinical / clinical pharmacology, specifically in cardiovascular pathophysiology, diabetic complications, medical devices, arthritis, and regenerative medicine, which has resulted in either patentable products and/or high impact publications.

My important scientific contributions (to date):
1. Pioneered novel feed mix strategy to prevent incidence of Ionophore toxicity in broiler farm, which reduced 20% morbidity and 35% production loss in Broiler industry. Recognised by Society of Toxicology with Young Scientist award.
2. Pioneered the Angiotensin II receptors and calcium channel functional coupling concept in development of diabetes associated vascular disorders. Recognised by Indian Pharmacological Society with Young Scientist award and PP Suriyakumari gold medal.
3. Discovery and development of novel oxidized sGC activators, Isoform specific NADPH oxidase inhibitors and AGE breakers.
4. Pioneering discovery of novel stem cell based small molecules for cardiac regeneration therapeutics.
5. Pioneering discovery of novel biopolymers for developing next generation of peptide eluting stents.
6. Pioneering discovery of novel biomarkers & therapeutics for identifying and treating unstable plaques (First in class therapeutics).
7. Pioneering development of cardiobiotics (First in class therapeutics / nutraceuticals).
8. Changing the phase of scientific journalism to enhance transparency and reliability.

Goals: Promoting socially responsible scientific innovations and pharmaceutical entrepreneurship
 
 

Professional

Honours and Awards

Year: 2015.
Title: Early Career Research Award
Year: 2015.
Title: UCD Career Development Award
Year: 2013.
Title: UCC innovation of the year award (Team member)
Year: 2013.
Title: UCC-Pfizer Team Innovation award 2013 (one of the top 6 shortlisted)
Year: 2012.
Title: Science Foundation Ireland - TIDA Entrepreneurship training award
Year: 2006.
Title: PP Suriyakumari Gold Medal from Pharmacological Society (India)
Year: 2005.
Title: Represented Indian embassy (Washington, USA) at the 55th Meeting of Nobel Prize Winners from 26th June to 1st July 2005 in Lindau, Germany
Year: 2004.
Title: PC Dandiya prize (Young Scientist Award) from the Indian Pharmacological Society
Year: 2003.
Title: Young Scientist Award from the Society of Toxicology
Year: 2001.
Title: CSIR-Senior Research Fellowship (2001-2004)
Year: 2001.
Title: Qualified UGC-CSIR National Eligibility Test for lectureship in Life Sciences
Year: 2000.
Title: Qualified ICAR ARS National Eligibility Test for Assistant Professorship in the subject of Pharmacology and Toxicology
Year: 2000.
Title: Topped the MVSc final grade list with 90.7% as aggregate score
Year: 1995.
Title: Col., Robert Gabriel Scholarship of merit from 1995-2000
Year: 1998.
Title: Stood 3rd in the final grade list of DVM with 91.5% as aggregate score (1993-1998)

Associations

Association: European Society of Cardiology, Function/Role: Member
Association: European Society of Interventional Cardiologist, Function/Role: Member
Association: Society of Toxicology, Function/Role: Life Member
Association: Indian Veterinary Association , Function/Role: Life Member
Association: The Science Advisory Board, Function/Role: Life Member
Association: European Society of Laboratory Animal Veterinarians, Function/Role: Life Member
Association: Global advisory board member for Sigma Aldrich, Function/Role: Member
Association: Phcog Net, Function/Role: Editor/Board Member
     

Conference Contributions

Kilroy, D; Kumar, AH (2017) Online Anatomy assessment versus the traditional methods: a comparative study of student performance. [Poster Presentation (Refereed)], Anatomists on the Edge: Joint meeting of Anatomical Society (GB and Ireland) and American Assocation of Anatomists, NUIG, Galway , 27-JUN-17 - 27-JUL-17.

Committees

Committee : Chair of the Examination Committee (PG Thesis)
Committee : UCD Widening Participation Committee
Committee : Institutional Animal Ethics Committee, University College Cork

Employment

Employer: University College Dublin
Position: Asst Professor (Biosciences)
Employer: University College Cork
Position: Senior Scientist
Employer: Rudolf-Buchheim-Institute For Pharmacology, UNiversity of Clinics Giessen, Germany
Position: Postdoctoral Scholar
Employer: MONASH University, Melbourne
Position: Medical Scientist
Employer: NIPER Mohali
Position: Senior Research Fellow
Employer: Torrent Pharmaceuticals Research Center
Position: Preclinical Scientist

Education

Year 2015 Institution: ALISON
Qualification: H Dip Statistics Subject: Statisitcs
Year 2015 Institution: ALISON
Qualification: Diploma Subject: Sustainable Development
Year 2015 Institution: UCD
Qualification: Professional Cert Management Subject: Teaching and Learning
Year 2015 Institution: UCD
Qualification: Post Graduate Certificate Subject: Research Supervisor Support and Development Programme
Year 2015 Institution: ALISON
Qualification: Diploma Subject: Six Sigma
Year 2014 Institution: ALISON
Qualification: Diploma Subject: Business and Legal Studies
Year 2014 Institution: ALISON
Qualification: Diploma of Education Subject: Teaching Skills for Educators
Year 1998 Institution: Veterinary College Bangalore
Qualification: DVM Subject:
Year 2000 Institution: Veterinary College Hyderabad
Qualification: Other Subject:
Year 2005 Institution: NIPER Mohali
Qualification: PhD Subject:
Year 1997 Institution: The British Institutes
Qualification: Nat Dip in Business Studies Subject: Business Administration and Management
Year 2009 Institution: VetMed Team, Florida
Qualification: Certificate Subject: Veterinary CPD
Year 2012 Institution: DCU Ryan Academy for Entrepreneurship
Qualification: Certificate Subject: Technology Venture Creation: Business and Entrepreneurship
Year 2000 Institution: ANGRAU
Qualification: Master of Science Subject: Veterinary (Pharmacology and Toxicology)
Year 2013 Institution: University College Cork
Qualification: Certificate Subject: Teaching and Learning for Researchers

Languages

English:
Hindi:
German:

Consultancy

Client: AAALAC
Client: Little flower Hospital and Research Centre
Client: The Science Advisory Board

Outreach Activities

Appointed as Peace Commissioner of Dublin and immediately adjoining counties, by the Minister of Justice and Equality.
MMI Annual Scientific Meeting 2015 (Judge Panel for poster session)
Represented Veterinary Medicine Faculty at Higher options carrier fair held in RDS, Dublin (23500 students/parents attended this event), 2013, 2015

Editor In Chief: Journal Natural Science Biology and Medicine (www.jnsbm.org).

Editor: Pharmacognosy Magazine, Pharmacognosy Reviews and Pharmacognosy Research (Journal covering natural product drug discovery topics).

Have reviewed for Nature Medicine, PNAS, Circulation, Circulation Research, Diabetes, Molecular Pharmacology, Biochemical Pharmacology, International J Toxicology, J Computer-Aided Molecular Design.

Worked as Editorial Assistant for CRIPS (Current Research Information in Pharmaceutical Sciences), an official publication of National Institute of pharmaceutical Education & Research (NIPER) from July 2001 to March 2004.

Judged the Debating in Science Competetions
http://www.remedi.ie/education/debating-science-issues-dsi-2010-2011

Journals Edited

Journal Of Natural Science, Biology And Medicine: Editor-in-Chief.
Bems Reports: Editor-in-Chief.
Pharmacognosy Magazine: Co-Editor.
Pharmacognosy Reviews: Co-Editor.
 

Publications

 

Book Chapters

Arun HS Kumar and Naresh Kumar Singh; (2011) 'Compromised cytology of bovine udder during mastitis: Therapeutic potential of adult stem/progenitor cells' In: Production diseases of dairy animals. Satish Serial Publishing House, Delhi, India. [Details]
Arun HS Kumar. ; (2008) 'Comprehensive Review of Literature' In: A edited `From getting started in research to presenting data in a scientific paper¿. Wolters Kulwer Health. [Details]
Mueen Ahmed KK and Arun Kumar HS. ; (2008) 'Phytopharmacological Screening of Natural Products' In: Text book of Industrial Pharmacy (Drug delivery systems and cosmetic and herbal drug technology). Orient Longman Pvt Ltd. [Details]
Mueen Ahmed KK and Arun Kumar HS. ; (2008) 'Patents and Intellectual Property on Natural Products - An Overview' In: Text book of Industrial Pharmacy (Drug delivery systems and cosmetic and herbal drug technology)¿. Orient Longman Pvt Ltd. [Details]
 

Peer Reviewed Journals

Alhaider IA, Mohamed ME, Ahmed KKM, Kumar AHS (2017) 'Date Palm (Phoenix dactylifera) Fruits as a Potential Cardioprotective Agent: The Role of Circulating Progenitor Cells'. Frontiers in Pharmacology, 8 (592):12-20. [DOI] [Details]
Kumar AHS (2017) 'The Dynamics of Technology in Revolutionizing Education and Research'. Journal of Natural Science, Biology and Medicine, 8 (2):137-138. [DOI] [Details]
Klinkert K, Whelan D, Clover AJ, Leblond AL, Arun HS Kumar, Caplice NM. (2017) 'Selective M2 Macrophage Depletion Leads to Prolonged Inflammation in Surgical Wounds'. European Surgical Research, 58 (3-4):109-120. [DOI] [Details]
Arun HS Kumar (2017) 'Vestibular stimulation for stress management: Attributing the vestibular system networks in potentially regulating physiology beyond body movements and balance'. Journal of Natural Science, Biology and Medicine, 8 (1):1-3. [Details]
Kilroy, D and Kumar, AH (2015) 'Dilemma in the diversity of foramen magnum dimensions'. BEMS Reports, 1 (1):3-6. Available Online [DOI] [Details]
David Kilroy and Arun HS Kumar (2016) 'Student-led collaborative learning enhances engagement in vet¬erinary neurophysiology lectures'. BEMS Reports, 2 (2):39-42. [DOI] [Details]
Yamuna V Kuberappaa and Arun HS Kumar (2016) 'Comparative assessment of digital and traditional marketing approaches'. BEMS Reports, 2 (2):55-58. [DOI] [Details]
Yamuna V Kuberappaa and Arun HS Kumar (2016) 'A case study on practical approaches to adopting digital market¬ing strategy'. BEMS Reports, 2 (2):39-43. [DOI] [Details]
Turner EC, Huang CL, Sawhney N, Govindarajan K, Clover AJ, Martin K, Browne TC, Arun H.S. Kumar, Mackrill JJ, Whelan D, Wang S, Schmeckpeper J, Stocca A, Pierce WG, Leblond AL, Cai L, Buneker CK, Choi J, MacSharry J, Ikeda Y, Russell SJ, Caplice NM (2016) 'A novel selectable ISL-1 positive progenitor cell reprogrammed to expandable and functional smooth muscle cells'. Stem Cells, . [DOI] [Details]
Arun HS Kumar (2016) 'Hoping rosuvastatin for primary prevention of cardiovascular events, are all statins similar and are we ready for statinizing the globe?'. Journal of Natural Science, Biology and Medicine, 7 (2):117-118. [DOI] [Details]
Yamuna V Kuberappa and Arun HS Kumar (2016) 'Operating system use pattern in accessing a digital marketing content posted in LinkedIn'. BEMS Reports, 1 (2):46-48. Available Online [DOI] [Details]
K.K. Mueen Ahmed and Arun HS Kumar (2016) 'Bibliometric analysis of Journal of Natural Science, Biology and Medicine (JNSBM): The Editors perspective'. BEMS Reports, 1 (2):49-52. [DOI] [Details]
Arun HS Kumar (2016) 'Novel biomarkers with potential utility in diagnosis of liver fibrosis'. BEMS Reports, 1 (2):39-40. [DOI] [Details]
Arun HS Kumar (2016) 'Precision editing the cells and engineering or re-engineering life, the era of geno-pharmacology/therapeutics has begun!!'. Journal of Natural Science, Biology and Medicine, 7 (1):1-3. [DOI] [Details]
Clover AJ, Arun HS Kumar, Isakson M, Whelan D, Stocca A, Gleeson BM, Caplice NM. (2015) 'Allogeneic mesenchymal stem cells, but not culture modified monocytes, improve burn wound healing'. Burns, 41 (3):548-557. [Details]
Arun H. S. Kumar and Anthony J. P. Clover (2015) 'Intraperitoneal co-administration of low dose urethane with xylazine and ketamine for extended duration of surgical anesthesia in rats'. Laboratory Animal Science, 31 (4):174-179. [DOI] [Details]
Kumar G, Arun HS Kumar (2015) 'Need for evidence-based practice at grass root level to improve child health and development'. Journal of Natural Science, Biology and Medicine, 6 :1-2. [DOI] [Details]
Jegatheeswaran AG, Arun HS Kumar (2015) 'Advancement in biochemical diagnostics and regenerative medicine leading to integration of dentistry into 360° health program'. Journal of Natural Science, Biology and Medicine, 6 :283-285. [DOI] [Details]
Ali MT, Martin K, Arun HS Kumar, Cavallin E, Pierrou S, Gleeson BM, McPheat WL, Turner EC, Huang CL, Khider W, Vaughan C, Caplice NM. (2015) 'A novel CX3CR1 antagonist eluting stent reduces stenosis by targeting inflammation'. Biomaterials, 3 (69):22-29. [DOI] [Details]
Leblond AL, Klinkert K, Martin K, Turner EC, Arun HS Kumar, Brown T, Caplice NM. (2015) 'Systemic and cardiac depletion of M2 macrophage through CSF-1R signaling inhibition alters cardiac function post myocardial infarction'. PLoS ONE, PONE-D-15-19506R1 . [Details]
Gleeson BM, Martin K, Ali MT, Arun HS Kumar, Pillai MG, Kumar SP, O'Sullivan JF, Whelan D, Stocca A, Khider W, Barry FP, O'Brien T, Caplice NM. (2015) 'Bone marrow-derived mesenchymal stem cells have innate procoagulant activity and cause microvascular obstruction following intracoronary delivery: Amelioration by anti-thrombin therapy'. Stem Cells, . [DOI] [Details]
David Kilroy and Arun HS Kumar (2015) 'Dilemma in the diversity of foramen magnum dimensions'. BEMS Reports, 1 (1):3-6. [Details]
Huang CL, Leblond AL, Turner EC, Arun HS Kumar, Martin K, Whelan D, O'Sullivan DM and Caplice NM (2015) 'Synthetic chemically modified mRNA-based delivery of cytoprotective factor promotes early cardiomyocyte survival post-acute myocardial infarction'. Molecular Pharmacology, . [DOI] [Details]
Arun HS Kumar (2015) 'Letter by kumar regarding article, contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis'. Circulation, . [Details]
Lis E.E. London, Arun HS Kumar, Rebecca Wall, Pat G Casey, Orla O¿Sullivan, Fergus Shanahan, Colin Hill, Paul Cotter, Gerald F. Fitzgerald, R Paul Ross, Noel M. Caplice and Catherine Stanton. (2014) 'Exopolysaccharide-producing probiotic lactobacilli improve cardiovascular disease risk factors in ApoE-deficient mice'. Nutrition, . [Details]
Chien-Ling Huang, Anne-Laure Leblond, Elizebeth C Turner, Arun H Kumar, Donnchadh M O¿Sullivan, Kenneth Martin, Derek Whelan, Noel M Caplice (2014) 'Synthetic Modified RNA Driven Delivery of Insulin-Like Growth Factor-1 Promotes Early Cardiomyocyte Survival Post-Acute Myocardial Infarction'. Circulation, 130 (2):A17201-A17202. [Details]
Arun HS Kumar (2014) 'Anatomy and physiology of peer review process, can it be unbiased?'. Journal of Natural Science, Biology and Medicine, 5 :1-2. [DOI] [Details]
Arun HS Kumar (2014) 'Open review system: The new trend in scientific reviewing to improve transparency and overcome biasness'. Journal of Natural Science, Biology and Medicine, 5 :231-232. [Details]
Arun HS Kumar, Kenneth Martin, Brendan J Doyle, Chien-Ling Huang, Gopala-Krishnan M Pillai, Mohammad T Ali, Kimberley A Skelding, Shaohua Wang, Birgitta M Gleeson, Saleem Jahangeer, Erik L Ritman, Stephen J Russell, Noel M Caplice. (2014) 'Stent-based Vascular cell Delivery for Therapeutic Angiogenesis'. Biomaterials, . [Details]
Hynes, Brian and Kumar, Arun H. S. and O'Sullivan, John and Buneker, Chirlei Klein and Leblond, Anne-Laure and Weiss, Sharon and Schmeckpeper, Jeffrey and Martin, Kenneth and Caplice, Noel M. (2013) 'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1'. European Heart Journal: Acute Cardiovascular Care, 34 (10):782-789. [DOI] [Details]
Elizebeth C Turner, Chien Ling Huang, Neya Sawhney, Kalai Govindarajan, Arun HS Kumar, James P Clover, Kenneth Martin, Anne-Laure Leblond, Sharon Wang, Noel M Caplice (2013) 'Identification Of A Novel Adult Smooth Muscle-like Stem/progenitor Cell That Facilitates Formation Of Tissue Engineered Vascular Tissue For Use As Vascular Grafts In Vivo'. Circulation Research, 113 (1):A120-A121. [Details]
Birgitta M Gleeson, Kenneth Martin, Arun H Kumar, Mohammed T Ali, Frank P Barry, Timothy O¿Brien, Noel M Caplice (2013) 'Prothrombotic Activity and Reduction in Coronary Flow Reserve Associated With Therapeutic Intracoronary Delivery of Bone Marrow-Derived Mesenchymal Stem Cells is Ameliorated by Heparin Co-Administration in a Porcine Myocardial Infarction Model'. Circulation, 128 (22):A19260-A19261. [Details]
Noel M Caplice, Brendan Doyle, Arun H Kumar, Kenneth Martin, Mohammed T Ali, Kimberley A Skelding, Shaohua Wang, Birgitta Gleeson, Erik L Ritman, Stephen J Russell (2013) 'Stent-Based Vascular Cell Delivery for Therapeutic VEGF-Induced Angiogenesis'. Circulation, 128 (22):A19130-A19131. [Details]
Hynes, B,Kumar, AHS,O'Sullivan, J,Buneker, CK,Leblond, AL,Weiss, S,Schmeckpeper, J,Martin, K,Caplice, NM (2013) 'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1'. European Heart Journal, 34 :782-789. Available Online [Details]
Martin K, Kumar AH, Klinkert K, Caplice NM (2013) 'Differential Endothelial Coverage, Response to Injury and Neointimal Integration of CX3CR1/Smooth Muscle-Like Cells after Carotid or Femoral Arterial Injury'. Journal of Vascular Research, 50 (3):200-209. Available Online [Details]
Abreu CM, Kumar R, Hamilton D, Dawdy AW, Creavin K, Eivers S, Finn K, Balsbaugh JL, O'Connor R, Kiely PA, Shabanowitz J, Hunt DF, Grenon M, Lowndes NF (2013) 'Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1'. Plos Genetics, 9 (4). Available Online [Details]
O'Sullivan JF, Leblond AL, O'Dea J, Hristova I, Kumar S, Martin K, Kumar AH, Caplice NM (2013) 'Multidetector computed tomography accurately defines infarct size, but not microvascular obstruction after myocardial infarction'. Journal of The American College of Cardiology, 61 (2):208-210. Available Online [Details]
O'Sullivan, John F. and Leblond, Anne-Laure and O'Dea, John and Hristova, Ivalina and Kumar, Sujith and Martin, Kenneth and Kumar, Arun H. S. and Caplice, Noel M. (2013) 'Multidetector Computed Tomography Accurately Defines Infarct Size, But Not Microvascular Obstruction After Myocardial Infarction'. JACC. Cardiovascular interventions, 61 (2):208-210. [DOI] [Details]
Kumar, Arun H. S. and Martin, Kenneth and Turner, Elizebeth C. and Buneker, Chirlei K. and Dorgham, Karim and Deterre, Philippe and Caplice, Noel M. (2013) 'Role of CX(3)CR1 Receptor in Monocyte/Macrophage Driven Neovascularization'. PLoS ONE, 8 (2). [DOI] [Details]
Clover, Anthony J. P. and O'Neill, Billy Lane and Kumar, Arun H. S. (2012) 'Analysis of attitudes toward the source of progenitor cells in tissue-engineered products for use in burns compared with other disease states'. WOUND REPAIR AND REGENERATION, 20 (3):311-316. [DOI] [Details]
JF O'sullivan, AL Leblond, G Kelly, AHS Kumar, P Metharom, CK Buneker, N Alizadeh-Vikali, BG Hynes, R O'connor, NM Caplice (2012) 'Potent long-term cardioprotective effects of single low dose insulin-like growth factor-1 (LD-IGF-1) treatment post myocardial infarction'. Cardiovascular Research, 93 :S59-S60. [Details]
J Clover, M Isakson, A Kumar, A Stocca, B Gleeson, N Caplice (2012) 'Allogeneic Mesenchymal Stem Cell Therapy Improves Burn Wound Healing via a Predominantly Paracrine Mechanism and Is Associated with Increased Collagen Deposition'. Plastic and Reconstructive Surgery, 130 (2s):488-489. [Details]
GM Kelly, OT Cox, AHS Kumar, NM Caplice, R O'Connor (2012) 'OR08-4 Cardioprotection by low-dose IGF-1 in myocardial infarct'. Growth Hormone and IGF Research, 22 (1):S21-S22. [Details]
Clover, AJP,O'Neill, BL,Kumar, AHS (2012) 'Analysis of attitudes toward the source of progenitor cells in tissue-engineered products for use in burns compared with other disease states'. Wound Repair And Regeneration, 20 :311-316. Available Online [Details]
O'sullivan, J. F. and Leblond, A. L. and Kelly, G. and Kumar, A. H. S. and Metharom, P. and Buneker, C. K. and Alizadeh-Vikali, N. and Hynes, B. G. and O'connor, R. and Caplice, N. M. (2012) 'Potent long-term cardioprotective effects of single low dose insulin-like growth factor-1 (LD-IGF-1) treatment post myocardial infarction'. Cardiovascular Research, 93 (1):S59. [Details]
A.J.P. Clover, Arun HS Kumar and Noel M Caplice (2011) 'Monocyte recruitment via the CX3CR1 receptor influences burn wound healing'. British Journal of Surgery, 98 (52 BP5):56. Available Online [Details]
Clover, A. J. P. and Kumar, A. H. S. and Caplice, N. M. (2011) 'Monocyte recruitment via the CX3CR1 receptor influences burn wound healing'. British Journal of Surgery, 98 (2):56. [Details]
Clover, A. J. P. and O'Neill, B. Lane and Kumar, A. H. S. (2011) 'Analysis of public attitudes towards the use of autologous and allogenic cells in tissue engineered products for burns'. BRITISH JOURNAL OF SURGERY, 98 (2):56. [Details]
Kumar, Arun H. S. and McCauley, Scott D. and Hynes, Brian G. and O'Dea, John and Caplice, Noel M. (2011) 'Improved protocol for processing stented porcine coronary arteries for immunostaining'. JOURNAL OF MOLECULAR HISTOLOGY, 42 (2):187-193. [DOI] [Details]
O'Sullivan, John F. and Leblond, Anne-Laure and Metharom, Pat and Kumar, Arun H. S. and Kelly, Geraldine and Hristova, Eva and Hynes, Brian and O'Connor, Rosemary and Caplice, Noel M. (2011) 'POTENT CARDIOPROTECTIVE EFFECTS OF LOW DOSE INSULIN-LIKE GROWTH FACTOR-1 (LD-IGF-1) TREATMENT POST MYOCARDIAL INFARCTION ARE MEDIATED THROUGH PHOSPHORYLATION OF THE IGF-1 RECEPTOR, GSK-3BETA INHIBITION AND SURVIVAL KINASE UPREGULATION'. JACC. Cardiovascular interventions, 57 (14, 1):E2050. [Details]
Metharom, Pat and Martin, Kenneth and Kumar, Arun H. S. and Sawhney, Neha and Cronin, Michael F. and McCarthy, Daniel G. and Maguire, Anita R. and Caplice, Noel M. (2011) 'Pleiotropic role for monocyte C-fms protein in response to vascular injury: Potential therapeutic target'. ATHEROSCLEROSIS, 216 (1):74-82. [DOI] [Details]
Clover, Anthony J. P. and Kumar, Arun H. S. and Caplice, Noel M. (2011) 'Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis'. Burns, 37 (8):1386-1393. [DOI] [Details]
A.J.P. Clover, B. Lane O¿Neill and Arun HS Kumar. (2011) 'Analysis of public attitudes towards the use of autologous and allogenic cells in tissue engineering products for burns'. British Journal of Surgery, 98 (52 BP6):56. Available Online [Details]
O'Sullivan JF, Leblond AL, Kelly G, Kumar AH, Metharom P, Büneker CK, Alizadeh-Vikali N, Hristova I, Hynes BG, O'Connor R, Caplice NM (2011) 'Potent long-term cardioprotective effects of single low-dose insulin-like growth factor-1 treatment postmyocardial infarction'. Circulation. Cardiovascular interventions, 4 (4):327-335. Available Online [Details]
Kumar AH (2011) 'Milestones, global presence, and scientific progress'. Journal of natural science, biology, and medicine, 2 (2):137-138. Available Online [Details]
Metharom P, Martin K, Kumar AH, Sawhney N, Cronin MF, McCarthy DG, Maguire AR, Caplice NM (2011) 'Pleiotropic role for monocyte C-fms protein in response to vascular injury: potential therapeutic target'. Atherosclerosis, 216 (1):74-82. Available Online [Details]
Hynes B, Kumar AH, O'Sullivan J, Klein Buneker C, Leblond AL, Weiss S, Schmeckpeper J, Martin K, Caplice NM (2011) 'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1'. European Heart Journal, . Available Online [Details]
Metharom, P,Martin, K,Kumar, AHS,Sawhney, N,Cronin, MF,McCarthy, DG,Maguire, AR,Caplice, NM; (2011) 'Pleiotropic role for monocyte C-fms protein in response to vascular injury: Potential therapeutic target'. Atherosclerosis, 216 :74-82. Available Online [Details]
Murphy, Grainne and Kumar, Arun and Shanahan, Fergus and Harney, Sinead and Molloy, Michael and Caplice, Noel (2011) 'CX3CR1 DEFICIENCY RESULTS IN PROTECTION FROM COLLAGEN-INDUCED ARTHRITIS IN A TRANSGENIC MOUSE MODEL'. Rheumatology, 50 :75-76. Available Online [Details]
Metharom P, Martin K, Kumar AH, Sawhney N, Cronin MF, McCarthy DG, Maguire AR, Caplice NM; (2011) 'Pleiotropic role for monocyte C-fms protein in response to vascular injury: Potential therapeutic target'. Atherosclerosis, 216 (1):74-82. Available Online [Details]
Clover AJ, Kumar AH, Caplice NM; (2011) 'Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis'. Burns : journal of the International Society for Burn Injuries, . Available Online [Details]
Kumar AH, McCauley SD, Hynes BG, O'Dea J, Caplice NM; (2011) 'Improved protocol for processing stented porcine coronary arteries for immunostaining'. Journal of Molecular Histology, 42 (2):187-193. Available Online [Details]
Taye, A,Saad, AH,Kumar, AHS,Morawietz, H; (2010) 'Effect of apocynin on NADPH oxidase-mediated oxidative stress-LOX-1-eNOS pathway in human endothelial cells exposed to high glucose'. European Journal of Pharmacology, 627 :42-48. Available Online [Details]
Metharom, P; Kumar, AHS; Weiss, S; Caplice, NM; (2010) 'A Specific Subset of Mouse Bone Marrow Cells Has Smooth Muscle Cell Differentiation Capacity-Brief Report'. Arteriosclerosis Thrombosis and Vascular Biology, 30 :533-357. Available Online [Details]
Kumar, Arun H. S. and Caplice, Noel M. (2010) 'Clinical Potential of Adult Vascular Progenitor Cells'. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 30 (6):1080-1087. [DOI] [Details]
Kumar, Arun H. S. and Metharom, Pat and Schmeckpeper, Jeff and Weiss, Sharon and Martin, Kenneth and Caplice, Noel M. (2010) 'Bone marrow-derived CX(3)CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX(3)CR1 interaction'. FASEB JOURNAL, 24 (1):81-92. [DOI] [Details]
Taye, Ashraf and Saad, Adel H. and Kumar, Arun H. S. and Morawietz, Henning (2010) 'Effect of apocynin on NADPH oxidase-mediated oxidative stress-LOX-1-eNOS pathway in human endothelial cells exposed to high glucose'. EUROPEAN JOURNAL OF PHARMACOLOGY, 627 (1-3):42-48. [DOI] [Details]
Kumar AH, Metharom P, Schmeckpeper J, Weiss S, Martin K, Caplice NM (2010) 'Bone marrow-derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction'. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24 (1):81-92. Available Online [Details]
Kumar, Arun HS; Caplice; Noel M; (2010) 'Clinical potential of adult vascular progenitor cells'. Atherosclerosis Thrombosis and Vascular Biology, 30 (6):1080-1087. Available Online [Details]
Kumar, Arun HS; Caplice; Metharom, Pat; Schmeckpeper, Jeffrey; Weiss, Sharon; Martin, Kenneth; Caplice, Noel M; (2010) 'Bone marrow derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction'. FASEB Journal, 24 (1):81-92. Available Online [Details]
Metharom, Pat; Kumar, Arun HS; Weiss, Sharon; Caplice, Noel M; (2010) 'A specific subset of mouse bone marrow cells has smooth muscle cell differentiation capacity'. Atherosclerosis Thrombosis and Vascular Biology, 30 (3):533-535. Available Online [Details]
Wind, Sven; Beuerlein, Knut; Armitage, Melanie E; Taye, Ashraf; Kumar, Arun HS; Janowitz, Daniel; Neff, Christina; Shah, Ajay M; Schmidt, Harald HHW; Wingler, Kirstin; (2010) 'Oxidative Stress and Endothelial Dysfunction in Aortae of Aged Spontaneously Hypertensive Rats by NOX1/2 is Reversed by NADPH Oxidase Inhibition'. Hypertension, 56 (3):490-497. Available Online [Details]
Arun HS Kumar, Brian G Hynes, Mueen Ahmed KK. ; (2009) 'Natural products as regulators of progenitor cells: Role in cardiovascular regenerative medicine'. Journal of Young Pharmacists, 1 (1):28-35. Available Online [Details]
Schmeckpeper, Jeffrey and Ikeda, Yasuhiro and Kumar, Arun H. S. and Metharom, Pat and Russell, Stephen J. and Caplice, Noel M. (2009) 'Lentiviral tracking of vascular differentiation in bone marrow progenitor cells'. DIFFERENTIATION, 78 (2-3, SI):169-176. [DOI] [Details]
Jeffrey Schmeckpeper, Yasuhiro Ikeda, Arun HS Kumar, Pat Metharom, Stephen J. Russell and Noel M Caplice. ; (2009) 'Lentiviral tracking of vascular differentiation in bone marrow progenitor cells'. Differentiation, 78 (2-3). Available Online [Details]
Singh NK, Lee HJ, Jeong DK, Eong DK, Arun HS Kumar, Sharma L, Hwang IH. ; (2009) 'Myogenic Satellite Cells and Its Application in Animals - A Review'. Asian-Australasian Journal of Animal Sciences, 22 (10):1447-1460. Available Online [Details]
Doyle, B,Sorajja, P,Hynes, B,Kumar, AHS,Araoz, PA,Stalboerger, PG,Miller, D,Reed, C,Schmeckpeper, J,Wang, S,Liu, CS,Terzic, A,Kruger, D,Riederer, S,Caplice, NM; (2008) 'Progenitor Cell Therapy in a Porcine Acute Myocardial Infarction Model Induces Cardiac Hypertrophy, Mediated by Paracrine Secretion of Cardiotrophic Factors Including TGF beta 1'. Stem Cells and Development, 17 :941-951. Available Online [Details]
Doyle, Brendan and Sorajja, Paul and Hynes, Brian and Kumar, Arun H. S. and Araoz, Phillip A. and Stalboerger, Paul G. and Miller, Dylan and Reed, Cynthia and Schmeckpeper, Jeffrey and Wang, Shaohua and Liu, Chunsheng and Terzic, Andre and Kruger, David and Riederer, Stephen and Caplice, Noel M. (2008) 'Progenitor Cell Therapy in a Porcine Acute Myocardial Infarction Model Induces Cardiac Hypertrophy, Mediated by Paracrine Secretion of Cardiotrophic Factors Including TGF beta 1'. STEM CELLS AND DEVELOPMENT, 17 (5):941-951. [DOI] [Details]
Authored by the Rat White Paper Writing Consortium (287 Authors). ; (2008) 'White Paper on rat research in the genome and post-genome era: a community view'. Nature Genetics, . Available Online [Details]
Arun HS Kumar. ; (2007) 'Radical radical everywhere, where is the perfect antioxidant?'. Pharmacognosy Magazine, 3 (12). Available Online [Details]
Saini AK, Arun Kumar HS and Sharma SS. ; (2007) 'Preventive and curative effect of edaravone on nerve functions and oxidative stress in experimental diabetic neuropathy'. European Journal of Pharmacology, . Available Online [Details]
Arun HS Kumar; (2007) 'Natural Remedies to Impotence. (Editorial)'. Phcog Mag, . Available Online [Details]
Arun Kumar HS; (2006) 'How are we progressing? (Editorial)'. Phcog Mag, . Available Online [Details]
Wind, S and Taye, A and Beuerlein, K and Eucker, T and Kronich, P and Kumar, AHS and Geyer, H and Wingler, K and Schmidt, HHHW (2006) 'Oxidative stress and endothelial dysfunction in aged spontaneously hypertensive rats can be reversed by inhibition of NADPH oxidase'. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 372 (1):92. [Details]
Saini AK, Patel RJ, Sharma SS and Arun Kumar HS; (2006) 'Edaravone attenuates hydroxyl radical stress and augmented angiotensin II response in diabetic rats'. Pharmacological Research, . Available Online [Details]
Johannes-Peter Stasch, Peter M Schmidt, Pavel I Nedvetsky, Tatiana Y Nedvetskaya, Arun Kumar HS, Sabine Meurer, Martin Deile, Ashraf Taye, Andreas Knorr, Harald Lapp, Helmut Müller, Yagmur Turgay, Christiane Rothkegel, Adrian Tersteegen, Barbara Kemp-Harper, Werner Müller-Esterl and Harald H.H.W. Schmidt. ; (2006) 'Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels. 2006'. Journal of Clinical Investigation, 116 :2552-2561. Available Online [Details]
Arun HS Kumar. ; (2006) 'Plant science and its noble contribution (Editorial)'. Phcog Mag, . Available Online [Details]
Arun KHS, Kaul CL and Ramarao P. ; (2005) 'Green fluorescent proteins in receptorology: An emerging tool in drug discovery'. Journal of Pharmacological and Toxicological Methods, . Available Online [Details]
Christiane Rothkegel, Peter M Schmidt, Arun Kumar HS, Friederike Stoll, Harald Lapp, Frank Wunder, Henning Schröder, Matthias Rinke, Harald HHW Schmidt and Johannes-Peter Stasch. ; (2005) 'Beyond NO and heme: biochemical and pharmacological opportunities'. BMC Pharmacology, . Available Online [Details]
Arun Kumar HS*, Manjunath HS and Reddy KS and Reddy R. Zeetress ; (2005) '(a polyherbal formulation of W. somnifera, O. sanctum, and E. officinalis) prevents salinomycin toxicity in broiler chicks'. Pharmacognosy Magazine, . Available Online [Details]
Hans Matter, Arun Kumar HS*, Roman Fedorov, Armin Frey, Peter Kotsonis, Elisabeth Hartmann, Lothar G. Fröhlich, Andreas Reif, Wolfgang Pfleiderer, Peter Scheurer, Dipak K. Ghosh, Ilme Schlichting and Harald HHW Schmidt. ; (2005) 'Structural analysis of isoform-specific inhibitors targeting the tetrahydrobiopterin binding site of human nitric oxide synthases'. Journal of medicinal chemistry, . Available Online [Details]
Arun KHS*, Kaul CL and Ramarao P. ; (2005) 'AT1 receptors and L-type calcium channels: functional coupling in supersensitivity to angiotensin II in diabetic rats'. Cardiovascular Research, . Available Online [Details]
Sokindra K, Arun KHS, Kaul CL and Sharma SS.; (2005) 'Effects of adenosine and adenosine A2A receptor agonist on motor nerve conduction velocity and nerve blood flow in experimental diabetic neuropathy'. Neurological Research, . Available Online [Details]
Neurological Research; (2005) 'Mother Nature¿s gift to combat oxidative stress'. Pharmacognosy Magazine, . Available Online [Details]
Arun Kumar HS. ; (2005) 'A meeting inspiring the young minds: Yet another noble venture from the Nobel laureates'. Pharmacognosy Magazine, . Available Online [Details]
Arun Kumar HS; (2005) 'Preclinical safety studies on medicinal plants: Part II'. Pharmacognosy Magazine, . Available Online [Details]
Arun Kumar HS. ; (2005) 'Where do we stand !!!. (Editorial)'. Phcog Mag, . Available Online [Details]
Arun Kumar HS; (2005) 'Preclinical safety studies on medicinal plants: Part 1'. Pharmacognosy Magazine, . Available Online [Details]
Arun Kumar HS* and Ramarao P. ; (2005) 'Saga of renin angiotensin system and calcium channels in hypertensive diabetics: Does it have a therapeutic edge?'. Cardiovascular Drug Reviews, . Available Online [Details]
Shilpi M, Alpeshkumar M, Selvam C, Arun KHS, Johar PS, Sanjay MJ, Ramarao P, Bharatam PV and Chawla HPS. ; (2004) 'Synthesis and Evaluation of S-4-(3-thienyl)phenyl-methylacetic acid'. Bioorganic and Medicinal Chemistry Letters, . Available Online [Details]
Volker O. Melichar, Delphine Behr-Roussel, Ulrike Zabel, L. Otto Uttenthal, José Rodrigo, Alain Rupin, Tony J. Verbeuren, Arun Kumar HS*, and Harald H.H.W. Schmidt. ; (2004) 'Reduced cGMP signaling associated with neointimal proliferation and vascular dysfunction in late stage atherosclerosis'. Proceedings of The National Academy of Sciences of The United States of America, . Available Online [Details]
Arun KHS, Kaul CL and Ramarao P. ; (2004) 'Tempol augments angiotensin II induced AT2-receptor mediated relaxation in diabetic rat thoracic aorta'. Journal of Hypertension, . Available Online [Details]
Arun KHS, Kaul CL and Ramarao P. ; (2004) 'In vitro high glucose concentration augments angiotensin II mediated contraction via AT1 receptors in control but not diabetic rat thoracic aorta'. Pharmacological Research, . Available Online [Details]
Saini AK, Arun KHS, Kaul CL, Sharma SS. ; (2004) 'Acute hyperglycemia attenuates nerve conduction velocity and nerve blood flow in male Sprague-Dawley rats: Reversal by adenosine'. Pharmacological Research, . Available Online [Details]
Ratan Kumar M, Kala Kumar B, Arun Kumar HS, and Reddy KS. ; (2004) 'Effect of ¿Zeetress¿ on aflatoxin depressed growth and immunity in broilers'. Indian Veterinary Journal, . Available Online [Details]
Arun KHS*, Manjunath HS, Reddy KS, Reddy R. ; (2003) 'Sub-acute oral toxicity of Salinomycin in broiler chicks'. Online Journal of Veterinary Research, . Available Online [Details]
Patel RJ, Prajapati KD, Arun KHS and Thyagarajan B; (2003) 'Ca2+ trapped in smooth muscle cell signal web'. Current Research and Information in Pharmaceutical Sciences, . Available Online [Details]
Arun KHS*, Manjunath HS, Reddy KS, Reddy R, Kala kumar B; (2003) 'Effect of sub-acute doses of Maduramycin in Broiler Chicks'. Online Journal of Veterinary Research, . Available Online [Details]
Ratan Kumar M, Arun Kumar HS*, Kala Kumar B. and Reddy KS. ; (2002) 'Effect of ¿Zeetress¿ on aflatoxin induced humoral immunosuppression in broiler chicks'. Indian Journal of Comparative Microbiology, Immunology and Infectious diseases, . Available Online [Details]
Arun Kumar HS*, Kala Kumar B. and Reddy KS. ; (2002) 'Acute toxicity studies on custard seed oil in mice'. Indian Veterinary Journal, . Available Online [Details]
Arun Kumar HS*, Kala Kumar B. and Reddy KS. ; (2001) 'Effect of custard seed oil on immune response of chicks vaccinated with NDV and S.gallinarum vaccine'. Phytomedica, . Available Online [Details]
Arun Kumar HS*, and Reddy TKK. ; (2001) 'Evaluation of the effect of glucose on thiopental anesthesia in mice'. Indian Veterinary Journal, . Available Online [Details]
Kala Kumar B, Arun Kumar HS*, Ashok Kumar B and Reddy KS. ; (2000) 'Evaluation of custard seed oil and neem oil as acaricides'. Journal of Veterinary Parasitology, . Available Online [Details]
Arun Kumar HS*, Kala Kumar B. and Reddy KS. ; (2000) 'Effect of ¿Zeetress¿ on immune response in custard seed oil induced immunosuppression in broiler chicks'. Phytomedica, . Available Online [Details]

Other Journals

David Kilroy, and Arun HS Kumar (2015) 'Dilemma in the diversity of foramen magnum dimensions' BEMS Reports . [Details]
Kumar G, Arun HS Kumar. (2015) 'Need for evidence-based practice at grass root level to improve child health and development' J Nat Sc Biol Med 6 (1) . [Details]
Arun HS Kumar. (2014) 'Open review system: The new trend in scientific reviewing to improve transparency and overcome biasness' J Nat Sc Biol Med 5 . [Details]
Arun HS Kumar. (2014) 'Anatomy and physiology of peer review process, can it be unbiased?' J Nat Sc Biol Med . [Details]
Arun HS Kumar. (2013) 'Rise in polluters of scientific research: How to curtail information pollution (infollution)' J Nat Sc Biol Med . [Details]
Zarros Apostolos, Arun HS Kumar. (2013) 'Digitization of DNA: Miniaturization of information storage moving toward data in DNA' J Nat Sci Biol Med 4 (1) :1-2. [DOI] [Details]
Arun HS Kumar (2012) 'The power of thought and potential of globalization of scientific research to overcome political and economic limitations' J Nat Sci Biol Med 3 (2) . [Details]
Arun HS Kumar. (2012) 'Effectively communicating the 5R's (replace, reduce, refine, reuse, and rehabilitate) of research ethics, biomedical waste, personalized medicines and the rest' J Nat Sci Biol Med 3 (1) . [Details]

Conference Publications

David Kilroy and Arun HS Kumar (2017) Student-led collaborative learning enhances engagement in veterinary neurophysiology lectures Anatomical Society Conference [Details]
R. Ortiz, A. Hassenforder, D. Kilroy, Arun HS Kumar and S. Aungier (2017) Research projects during the preclinical curriculum contribute to teaching evidence-based clinical-medicine Anatomical Society Conference [Details]
Ross McGeogh, Shane Comer, Alfonso Blanco-Ferna´ndez and Arun HS Kumar (2017) CX3CR1 positive myeloid cells regulate vascular smooth muscle tone by inducing calcium oscillations via activation of IP3 receptors European Society of Cardiology Conference [Details]
Wan Ting Lin, Colleen Bourque, David Kilroy, Arun HS Kumar. (2017) Evaluation of Iris-pupillary ratio as a non-invasive biomarker of higher sympathetic activity in hypertensive canines and felines 33rd World Veterinary Congress (WVC) [Details]
Baird A, Arun HS Kumar and Kilroy D (2017) Comparative ultrastructure and mineral composition of canine sesamoid bones Anatomical Society Conference [Details]
Turner EC, Huang CL, Sawhney N, Govindarajan K, Kumar AHS, Clover JP, Martin K, Leblond AL, Wang S, and Caplice NM (2013) Identification of a novel adult smooth muscle-like stem/progenitor cell that facilitates formation of tissue engineered vascular tissue for use as vascular grafts in vivo American Heart Association (AHA), BCVS, Las Vegas, USA, 2013 [Details]
Arun HS Kumar, Kenneth Martin, Noel M Caplice (2011) Deficiency of CX3CR1 Receptors Results in Formation of Leaky Microvessels in Plaque Atherosclerosis Thrombosis and Vascular Biology Conference. 28th-30th April 2011. Hilton, Chicago, Illinois, USA. (Abstract # 220) [Details]
Pat Metharom, Kenneth Martin, Arun HS Kumar, Noel M Caplice. (2011) Pleiotropic Role for Monocyte C--‐fms Protein in Response to Vascular Injury:=Potential Therapeutic Target Atherosclerosis Thrombosis and Vascular Biology Conference, 28th--‐30th April 2011. Hilton, Chicago, Illinois,USA [Details]
John F O¿Sullivan, M.D., Anne-Laure Leblond, PhD, Geraldine Kelly, BSc, Arun HS Kumar DVM, PhD, Pat Metharom, PhD, Chirlei K Büneker, PhD, Niki Alizadeh-Vikali, MSc, BHSc, Ivalina Hristova, BS, Brian G Hynes, M.D., Rosemary O¿Connor, PhD, Noel M Caplice, (2011) Potent Long-term Cardioprotective Effects of Single Low Dose Insulin-like Growth Factor-1 (LD-IGF-1) Treatment Post Myocardial Infarction Irish Cardiac Society, Winner YIA [Details]
John F. O'Sullivan, Anne-Laure Leblond, Pat Metharom, Arun HS Kumar, Geraldine Kelly, Eva Hristova, Brian Hynes, Rosemary O'Connor, and Noel M. Caplice (2011) POTENT CARDIOPROTECTIVE EFFECTS OF LOW DOSE INSULIN-LIKE GROWTH FACTOR-1 (LD-IGF-1) TREATMENT POST MYOCARDIAL INFARCTION ARE MEDIATED THROUGH PHOSPHORYLATION OF THE IGF-1 RECEPTOR, GSK-3BETA INHIBITION AND SURVIVAL KINASE UPREGULATION- American College of Cardiology, Winner Cardiovascular Pharmacology YIA [Details]
B Hynes, Arun HS Kumar, S Weiss, J O¿Sullivan, K Martin, G Murphy, NM Caplice. (2009) European Society of Cardiology Congress 2009. (Abstract # 86618) Evaluating the effect of everoliums on cardiomyocyte apoptosis in both an in-vitro model of hypoxia and an in-vivo drug eluting stetting post myocardial infarction [Details]
Arun HS Kumar, Brian G Hynes, Mueen Ahmed KK. (2009) Natural products as regulators of progenitor cells: Role in cardiovascular regenerative medicine International Herbal Conference (Herbal Medicine-Evaluation of quality, efficiency and safety) 26th-28th Feb 2009. www.herbalconference2009.com. P26-37 [Details]
B Hynes, Arun HS Kumar, S Weiss, J Schmeckpeper, K Martin, NM Caplice. (2009) Transforming growth factor beta and insulin like growth factor one play a key role in the beneficial paracrine effects of endothelial progenitor cells in myocardial salvage post infarction European Society of Cardiology Congress 2009. (Abstract # 84552) [Details]
A Mohamed, B Hynes, A Kumar, G Murphy, A Elsiddig, K Bennett, V Young, M Tolan, E mcgovern, D Keane. (2008) Acute epicardial multi-site biventricular pacing after coronary artery bypass surgery European Society of Cardiology. 30th Aug-3rd Sept 2008; Munich, Germany. P4690. European Heart Journal (2008) 29 (Abstract Supplement), 810 [Details]
Arun HS Kumar. (2007) Large animal imaging and Translational animal facility Research Interaction Workshop. Royal College of Surgeons, Dublin, Ireland. 2007 [Details]
Stasch JP, Rothkegel C, Arun Kumar HS, Wunder F, Schroeder H, Schmidt HHHW, Schmidt PM. (2005) NO- and heme-independent activation of soluble guanylate cyclase: Biochemical and Pharmacological opportunities Ist International Conference on Frontiers in Vascular Medicine 2005, Melbourne, Australia, p 46 [Details]
Arun Kumar HS. (2005) Vasoconstrictors and calcium channels: Does the romance couple in a sweet way? Ist International Conference on Frontiers in Vascular Medicine 2005, Melbourne, Australia, p 46 [Details]
Arun KHS, Kaul CL and Ramarao P. (2004) Augmented angiotensin II induced relaxation via AT2-receptor in diabetic vasculature 1st Asian Symposium for pharmaceutical Sciences 2004, Fukuoka, Japan, p 78-79 [Details]
Arun KHS, Martin Deile and Harald H.H.W. Schmidt. (2004) Selective augmented vasorelaxing efficacy of BAY 58-2667 versus nitric oxide under oxidative stress 9th NO forum der deutschsprachigen laender-2004. Mainz, Germany. p 22 [Details]
Arun Kumar HS, Kaul CL and Ramarao P. (2004) Functional coupling of AT1 receptor and dihydropyridine sensitive L-type calcium channel via phospholipase D-diacylglycerol pathway in rat thoracic International symposium on Recent Advances in Pharmacology- 2004. New Delhi, India, p 128-129 [Details]
Arun KHS, Srikumar BN, Ramarao P and Kaul CL. (2004) Role of superoxides in supersensitivity to angiotensin II in diabetic rat thoracic aorta 1st Asian Symposium for pharmaceutical Sciences 2004, Fukuoka, Japan, p 92-93 [Details]
Saini AK, Arun Kumar HS, Kaul CL and Sharma SS. (2003) Acute hyperglycemia attenuates nerve conduction velocity and nerve blood flow in healthy male Sprague-Dawley rats Indian Pharmacological Society Conference (IPS-2003). New Delhi, India, p 152 [Details]
Arun Kumar HS, Manjunath HS, Reddy KS, Ramasubba Reddy & Kalakumar B. (2003) Sub acute oral toxicity of maduramycin in broiler chicks: role of antioxidant enzymes and biochemical profiles 23rd annual conference of Society of Toxicology, 2003. Chennai, India [Details]
Arun Kumar HS, Kaul CL and Ramarao P. (2003) Functional coupling of AT1 receptors and dihydropyridine sensitive divalent cation channels in angiotensin II induced contraction in rat thoracic aorta Indian Pharmacological Society Conference (IPS-2003). New Delhi, India, p 150 [Details]
                                                                                                                                       

Research

Research Interests

Preclinical pharmacology, vascular and cardiovascular disease research, microsurgery, preclinical imaging, regenerative medicine and cell biology. 
Research Techniques
Vascular, cardiovascular and neurovascular functional phenotyping as part of preclinical and safety pharmacology.
Imaging: Intravital, fluoroscopy, multiphoton, confocal microscopy, CT-PET, SEM.
Preclinical drug discovery: GLP based In vivo and in vitro pharmacodynamic and pharmacokinetic studies.
Developing rodent and porcine models of vascular and myocardial remodelling.
Creating animal models of diabetes, hypertension and inflammation.
Expertise in 2D and 3D Image analysis (IMARIS software).
Single cell functional phenotyping (Endothelial and smooth muscle progenitor cells, cardiomyocytes, monocytes, macrophages, smooth muscle and endothelial cell primary cultures and established cell lines).
Pathological, histopathological, immunohistochemistry and biochemical techniques.
Rodent and porcine colony management.
Statistical evaluation of biological data.

Project management skills
Have independently/as team member managed the following research projects:
Role of Progenitor cells in cardiovascular pathophysiology.
Cardio protective effects of low dose IGF1 .
CX3CR1 cytokine network in restenosis and plaque angiogenesis.
Developing next generations of cytokine eluting stents.
Developing progenitor cells/secreted factors for treating burn wounds.
Studies on the role of NADPH Oxidases and soluble Guanylyl Cyclases in cardiovascular/vascular/neurological pathophysiology. (Postdoc).
Studies on the role of calcium channels on angiotensin responses in diabetic rat vasculature (Ph.D. Thesis).
Studies on the role of antioxidants in combating salinomycin and maduramycin toxicity in broiler chicks (M.V.Sc Thesis).
Role of oxidative stress in enhanced vascular and nonvascular contractions in diabetic rats.
Acute hyperglycemic effects induced changes in motor nerve conduction velocity and nerve blood flow: Identifying the mechanisms involved.
Role of oxidative stress and adenosinergic receptors in diabetic neuropathy.
Advanced glycation end product breakers in combating type I & II diabetic vascular complications. (Industrial Project).
Dipeptidyl peptidase IV inhibitors in therapy of type II diabetes. (Industrial Project).
Screening of novel diclofenac formulations for their analgesic and anti-inflammatory activity in rodent model. (Industrial Project).
 
Grants/Fellowships
Enterprise Ireland Commercialization fund Programme.Heart friendly probiotic (MUCOL), Catherine Stanton, Noel Caplice, Arun HS Kumar, Paul Ross, Ger Fitzgerald, Fergus Shanahan. (2013-2016).
Date Palm Research Center Grant, KSA. Evaluating the therapeutic potential of water-soluble compounds extracted from Phoenix dactylifera (Date fruits) in myocardial infarction: Role of circulating progenitor cells. Ibrahim A.Alhaider, Mueen Ahmed KK, Arun HS Kumar. (2013-2015).
Science Foundation Ireland-TIDA Entrepreneurship award. Arun HS Kumar. (2011-2012)
British Burns Association Research Grant. James Clover and Arun HS Kumar. Application of circulating progenitor cells on the burn wound to enhance the rate of burn wound healing. (2010-2011).
Enterprise Ireland. Development of IGF1 stent. Noel M Caplice and Arun HS Kumar. (2010-2011).
Irish Heart Foundation. Cardiac Angiogenesis: Cell based bypass of chronic vascular occlusions. Brian G Hynes and Arun Kumar HS. (2007-2009).
NHMRC Grant (384163), Australia. Defining the role of NADPH oxidases in vascular remodelling and arterial hypertension. Grant Drummond, Arun Kumar HS, Harald HHW Schmidt, Chris Sobby and Robert Widdop. (2006 to 2008).
Senior Research Fellowship, CSIR, India. Studies on the role of calcium channels on angiotensin responses in diabetic rat vasculature. Arun Kumar HS. (2001 to 2004).

Research Projects

Sponsor : University College Dublin (UCD)
Title : OBRSS Research Support Scheme
Start Date / End Date : 01-NOV-16 / 31-OCT-19
Sponsor : University College Dublin (UCD)
Title : Developing and validating a mouse model of unstable plaque for preclinical screening of atherosclerotic plaque stabilization therapeutics
Start Date / End Date : 01-APR-15 / 30-SEP-17
 

Current Postgraduate Students

Ross Mc Geough, Master of Science (MSc)   -   Thesis Supervisor

Teaching

Teaching Philosophy

Maintaining a students interest is a very challenging task and keen interest in addressing this challenge makes me fond of teaching. It gives me immense satisfaction when I spark a students interest in understanding the fundamentals of science, biology, medicine and pharmacology in particular.

Modules Coordinated

201700   VET30360     Veterinary Medicine: Neurobiology & head structure
201700   VET40460     Veterinary Medicine: TEARAP
       

Collaborators

Internal Collaborators

Prof. Alan Baird
Dr. David Kilroy

External Collaborators

Dr Raghavendra R (Material Science), SEAM.
Dr. Al-Haider I (Natural Products), KFU.