Researchers at UCD


Sourav Bhattacharjee


School Of Veterinary Medicine



Dr. Sourav Bhattacharjee finished his degree in Medicine (MBBS) from Medical College Kolkata in 2004. After a brief period of Resident training in Orthopedic Surgery he joined MSc in Biomolecular Sciences/Cell Biology in the Vrije Universiteit Amsterdam (2006). In the meanwhile he moved to Edinburgh (UK) where he worked for almost 14 months under the supervision of Prof. Vicki Stone in the Napier University. Upon finishing MSc he began his PhD in the Wageningen University (Netherlands) in 2008 which he successfully defended in 2012 with a very good thesis grade and quite few research papers. Following that he worked for almost an year as postdoc in MESA+ Institute of Nanotechnology in University of Twente (Netherlands). From March 2014 he joined Prof. David Brayden's group in UCD as postdoc working on EU FP7 funded TRANS-INT consortium trying to develop nanoparticulate drug delivery platforms for oral insulin delivery. From February 2016 Sourav joined UCD School of Veterinary Medicine as Lecturer in Veterinary Anatomy while also trying to develop his own niche of research encompassing a broad range of nanobiotechnology and advanced microscopy tools for effective diagnostic and drug delivery platforms.



Peer Reviewed Journals

Ruizendaal L, Bhattacharjee S, Pournazari K, Rosso-Vasic M, de Haan LHJ, Alink GM, Marcelis ATM, Zuilhof H (2009) 'Synthesis and cytotoxicity of silicon nanoparticles with covalently attached organic monolayers'. Nanotoxicology, 3 (4):339-347. [Details]
Clift MJ, Bhattacharjee S, Brown DM, Stone V (2010) 'The effects of serum on the toxicity of manufactured nanoparticles'. Toxicology Letters, 198 (3):358-365. [Details]
Bhattacharjee S, de Haan LH, Evers NM, Jiang X, Marcelis AT, Zuilhof H, Rietjens IM, Alink GM (2010) 'Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells'. Particle and Fibre Toxicology, 7 :25. [Details]
Bhattacharjee S, Ershov D, Fytianos K, van der Gucht J, Alink GM, Rietjens IM, Marcelis AT, Zuilhof H (2012) 'Cytotoxicity and cellular uptake of tri-block copolymer nanoparticles with different size and surface characteristics'. Particle and Fibre Toxicology, 9 :11. [Details]
Bhattacharjee S, Rietjens IM, Singh MP, Atkins TM, Purkait TK, Xu Z, Regli S, Shukaliak A, Clark RJ, Mitchell BS, Alink GM, Marcelis AT, Fink MJ, Veinot JG, Kauzlarich SM, Zuilhof H (2013) 'Cytotoxicity of surface-functionalized silicon and germanium nanoparticles: the dominant role of surface charges'. Nanoscale, 5 (11):4870-4883. [Details]
Bhattacharjee S, Ershov D, Gucht Jv, Alink GM, Rietjens IM, Zuilhof H, Marcelis AT (2013) 'Surface charge-specific cytotoxicity and cellular uptake of tri-block copolymer nanoparticles'. Nanotoxicology, 7 (1):71-84. [Details]
Bhattacharjee S, van Opstal EJ, Alink GM, Marcelis ATM, Zuilhof H, Rietjens IMCM (2013) 'Surface charge-specific interactions between polymer nanoparticles and ABC transporters in Caco-2 cells'. Journal of Nanoparticle Research, 15 (6):1-14. [Details]
Bhattacharjee S, Marcelis ATM, Zuilhof H, Woutersen R, Rietjens IMCM, Alink GM (2013) 'Role of surface charge in bioavailability and biodistribution of tri-block copolymer nanoparticles in rats after oral exposure'. Toxicology Research, 2 :187-192. [Details]
van der Ploeg MJ, van den Berg JH, Bhattacharjee S, de Haan LH, Ershov DS, Fokkink RG, Zuilhof H, Rietjens IM, van den Brink NW (2014) 'In vitro nanoparticle toxicity to rat alveolar cells and coelomocytes from the earthworm Lumbricus rubellus'. Nanotoxicology, 8 (1):28-37. [Details]
Bhattacharjee S, Ershov D, Islam MA, Kaempfer AM, Maslowska KA, van der Gucht J, Alink GM, Marcelis ATM, Zuilhof H, Rietjens IMCM (2014) 'Role of membrane disturbance and oxidative stress in the mode of action underlying the toxicity of differently charged polystyrene nanoparticles'. RSC Advances, 4 (37):19321-19330. [Details]
Bhattacharjee S (2015) 'Emerging trend of advanced image analysis in nanomedicine'. Nanomedicine (London, England), 10 (18):2801-2804. [Details]
Bhattacharjee S, Brayden DJ (2015) 'Development of nanotoxicology: Implications for drug delivery and medical devices'. Nanomedicine (London, England), 10 (14):2289-2305. [Details]


Research Interests

My research interests mostly focus on designing smart nanoparticulate systems for advanced diagnostics and therapeutic drug delivery systems. In order to do so, I have developed collaborations with both UCD School of Chemistry and UCD Conway Imaging facility. I am keen in developing advanced imaging tools to track nanoparticles 3D within microfluidic devices in physiologically relevant hydrogels (e.g. mucus) and develop mathematical models.


Internal Collaborators

Prof. Alan Baird (UCD School of Veterinary Medicine)
Prof. Stephen D. Carrington (UCD School of Veterinary Medicine)
Prof. Gareth Redmond (UCD School of Chemistry & Chemical Biology) 
Dr. Dimitri Scholz (UCD Conway Imaging Core facility)
Dr. Vladimir Lobaskin (UCD School of Physics)
Dr. Sabine Harrison (School of Agriculture & Food Science)
Dr. Eugene Mahon (UCD Conway Institute)

External Collaborators

Prof. Antonio Almeida (iMed University of Lisbon, Portugal)
Dr. Manuela Gaspar (iMed University of Lisbon, Portugal)
Prof. Maria-Jose Alonso (Universidad de Santiago de Compostela, Spain)