Researchers at UCD


Stephen Gordon


School Of Veterinary Medicine
Veterinary Science Centre
Dublin 4

Tel: +353 1 7166181


I hold a joint appointment across the School of Veterinary Medicine, School of Biomolecular and Biomedical Science, and School of Medicine and Medical Science.
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2008- : Professor, UCD. 
1999-2007: TB Research Group, VLA Weybridge, UK.
1995-1999: Wellcome Trust Travelling Fellow, Institute Pasteur, Paris.
1995: Wellcome Trust Junior Fellow University of Leicester, UK.
1991-1995: PhD, Wellcome Trust Prize Student, University of Leicester, UK.
1990-1991: Research Assistant, Natl. University of Ireland, Galway
1986-1990: BSc (Hons) Natl. University of Ireland, Galway.



Conference Contributions

Stephen Gordon (2016) Tuberculosis and One Health: Comparative analyses of the bovine and human tubercle bacilli. [Invited Oral Presentation], Tuberculosis 2016: Interdisciplinary research on tuberculosis and pathogenic mycobacteria, Institute Pasteur, Paris, France , 19-SEP-16 - 23-SEP-16.
Stephen Gordon (2016) Tuberculosis and One Health: Comparative analyses of the human and bovine tubercle bacilli. [Plenary Lecture], International Colloquium on Paratuberculoisis 2016, Nantes, France , 20-JUN-16 - 24-JUN-16.
Stephen V. Gordon (2016) Tuberculosis and One Health: comparative analysis of human and bovine tubercle bacilli. [Invited Lecture], Microbiology Society Annual General Meeting, Liverpool, UK , 22-MAR-16 - 22-MAR-16.
Stephen Gordon (2017) Exploring the basis of host preference in the human and bovine tubercle bacilli. [Invited Lecture], Departmental Seminar, University of Warwick , 17-FEB-17 - 17-FEB-17.
Stephen Gordon (2017) One Health Insights into Tuberculosis. [Invited Oral Presentation], Turning the Tide of Antimicrobial Resistance TTA Nordic, Oslo, Norway , 27-APR-17 - 28-APR-17.
Stephen Gordon (2017) Tuberculosis and One Health. [Invited Oral Presentation], UK Veterinary Vaccinology Network Conference 2017, QUB, Belfast, UK , 16-JAN-17 - 17-JAN-17.
Gordon SV (2015) The Mycobacterium tuberculosis complex as a One Health paradigm. [Plenary Lecture], 3rd Sapporo Summer Seminar for One Health, Hokkaido Univeristy, Sapporo Japan , 16-SEP-15 - 17-SEP-15.
Gordon SV (2015) Tuberculosis and One Health: adventures with Mycobacterium bovis. [Plenary Lecture], 4th MycoClub Meeting, Marseille, France , 06-MAY-15 - 07-MAY-15.
Gordon SV (2015) Tuberculosis and One Health: adventures with Mycobacterium bovis. [Invited Lecture], Departmental seminar, National Animal Disease Center, Ames, Iowa, USA , 22-JUN-15 - 22-JUN-15.
Gordon SV (2014) Session Chair: Bacterial secretion systems and virulence mechanisms. [Chaired Session], Genomes 2014: Microbiology after the genomics revolution, Institute Pasteur, Paris, France , 24-JUN-14 - 27-JUN-14.
Gordon SV (2014) Comparative analyses of the human- and animal-adapted strains of the Mycobacterium tuberculosis complex. [Keynote Address], International Union of Microbiological Societies 2014, Montreal, Canada , 27-JUL-14 - 01-AUG-14.
SV Gordon (2014) Exploring host preference across the Mycobacterium tuberculosis complex. [Invited Lecture], Departmental seminar, INRA Nouzilly, France , 11-APR-14 - 11-APR-14.
SV Gordon (2014) Comparative analyses of the human- and animal-adapted strains of the Mycobacterium tuberculosis complex. [Keynote Address], International Union of Microbiological Societies 2014, Montreal, Canada , 27-JUL-14 - 01-AUG-14.
SV Gordon (2014) Genomic Insights into the Biology of Mycobacterium bovis. [Plenary Lecture], VI International M.bovis conference, Cardiff, UK , 16-JUN-14 - 19-JUN-14.
Gordon SV (2013) Exploring Host tropism across the Mycobacterium tuberculosis complex. [Invited Oral Presentation], Irish Society for Immunology Annual Meeting, Dublin , 12-SEP-13 - 13-SEP-13.
Gordon SV (2013) Mycobacterial genomics and TB disease control. [Invited Oral Presentation], Institute for Infection Biology Seminar Series, University of Liverpool UK , 15-MAR-13 - 15-MAR-13.
Stephen Gordon (2012) Next Generation analysis of Mycobacterium bovis. [Plenary Lecture], 1st Mycobacterium bovis American Regional Conference, Merida, Mexico , 19-AUG-12 - 22-AUG-12.
Stephen Gordon (2012) Session Chair: Closing keynote lectures. [Chaired Session], Tuberculosis 2012: Biology, Pathogenesis, Intervention Strategies, Institut Pasteur, Paris, France , 11-SEP-12 - 15-SEP-12.
Stephen Gordon (2011) Application of pathogen genomics to TB disease control. [Invited Lecture], Roslin Institute Dept. Seminars, Roslin Institute, Edinburgh, Scotland , 15-JUN-11 - 15-JUN-11.
Gordon SV; (2010) The molecular evolution of the BCG Vaccine strain. [Plenary Lecture], Latin American Society of Tuberculosis, Zacatecas, Mexico , 23-AUG-10 - 25-AUG-10.
Gordon SV; (2010) The application of genomics to TB Disease control. [Invited Oral Presentation], Society for General Micorbiology Annual Meeting, Edinburgh, Scotland , 29-MAR-10 - 01-APR-10.
Gordon SV; (2010) Tuberculosis in humans and cattle in Ethiopia: Implications for public health. [Invited Lecture], Trinity International Development Initiative, Trinity College Dublin , 26-FEB-10 - 26-FEB-10.
Stephen Gordon; (2010) Application of genomics to TB disease control. [Invited Lecture], Dept. Genomes and Genetics, Institute Pasteur. Paris , 30-SEP-10 - 30-SEP-10.
Gordon SV; (2009) Mycobacterial Molecular Genetics. [Invited Oral Presentation], Many Hosts of Mycobacteria, Louisianna , 16-NOV-09 - 17-NOV-09.
Gordon SV; (2008) Genomic Analyses of BCG vaccine strains. [Plenary Lecture], 29th Annual Congress European Society of Mycobacteriology, Plovdic, Bulgaria , 06-JUL-08 - 09-JUL-08.
Gordon SV; (2008) Exploring the genetic basis for host preference between Mycobacteirum tuberculosis and Mycobacterium bovis. [Invited Lecture], Global Health Institute, EPFL, Lausanne, Switzerland , 26-MAY-08 - 26-MAY-08.
Gordon, SV; (2008) Functional Genomics of the Mycobacterium tuberculosis complex: BCG. [Invited Oral Presentation], International Congress of Bacteriology and Applied Microbiology, Istanbul, Turkey , 05-AUG-08 - 09-AUG-08.


Committee : DAFM Scientific Advisory Committee for Animal Health and Welfare
Committee : Veterinary Council of Ireland


Year 1995 Institution: University of Leicester
Qualification: PhD Subject:
Year 1990 Institution: NUI Galway, IRL
Qualification: BSc Subject:

Journals Edited

Tuberculosis: Editorial Board member.
Microbiology-Sgm: Editorial Board member.



Book Chapters

Alicia Smyth and Stephen V. Gordon (2018) 'Molecular virulence mechanisms of Mycobacterium bovis' In: M. Chamber, S. Gordon, F Oleka-Popelka, P. Barow (eds). Bovine Tuberculosis. Oxfordshire UK: CABI. , pp.106-121 [Details]
Stephen V. Gordon and Marcel A. Behr (2015) 'Comparative Mycobacteriology of the Mycobacterium tuberculosis complex' In: Mark Chambers, Harshini Mukundan, Michelle Larsen, W. Ray Waters (eds). Many Hosts of Mycobacteria: Tuberculosis, Leprosy, and other Mycobacterial Diseases of Man and Animals. Wallingford, UK: CAB International. [DOI] Link to full text [Details]
Gordon, SV and Pym, AS; (2008) 'Genomics of the Mycobacterium tuberculosis complex' In: Kaufmann, SHE and Rubin, E (eds). Hanbook of Tuberculosis. Weinheim: Wiley-VCH. , pp.193-211 [Details]
Gordon, SV and Brosch, R; (2005) 'Genomics of the Mycobacterium tuberculosis complex and Mycobacterium leprae' In: Gordon, SV and Brosch, R; (eds). Encyclopaedia of Genetics, Genomics, Proteomics and Bioinformatics. -: Wiley Interscience. [Details]
Gordon SV and Supply P; (2004) 'Repetitive DNA in the M. tuberculosis complex' In: Gordon SV and Supply P; (eds). Tuberculosis and the tubercle bacillus. Washington, DC: ASM Press. [Details]
Cole ST, Bentley SD, Brosch R, Gordon SV, and Hopwood DA ; (2004) 'Genomics of Actinobacteria, the High G+C of Gram-Postive Bacteria' In: Cole ST, Bentley SD, Brosch R, Gordon SV, and Hopwood DA ; (eds). Microbial Genomes. -: Humana Press. [DOI] [Details]
Behr, Ma and Gordon, SV; (2002) 'Genomics of the Mycobacterium tuberculosis Complex and BCG Vaccines' In: Behr, Ma and Gordon, SV; (eds). Pathogen Genomics: Impact on Drug Discovery. USA: Blackwell. [Details]

Edited Books

Mark Chambers, Stephen Gordon, Francisco Olea-Popelka, Paul Barrow (Ed.). (2018) Bovine Tuberculosis. Oxfordshire UK: CABI. [Details]

Peer Reviewed Journals

Gordon SV, Parish T (2018) 'Microbe Profile: Mycobacterium tuberculosis: Humanity's deadly microbial foe'. Microbiology (Reading, England), 164 (4):437-439. [DOI] [Details]
Villarreal-Ramos B, Berg S;Whelan A;Holbert S;Carreras F;Salguero FJ;Khatri BL;Malone K;Rue-Albrecht K;Shaughnessy R;Smyth A;Ameni G;Aseffa A;Sarradin P;Winter N;Vordermeier M;Gordon SV (2018) 'Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle'. Scientific Reports, 8 (1). [DOI] [Details]
Malone KM, Rue-Albrecht K;Magee DA;Conlon K;Schubert OT;Nalpas NC;Browne JA;Smyth A;Gormley E;Aebersold R;MacHugh DE;Gordon SV (2018) 'Comparative 'omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli'. Microbial Genomics, . [DOI] [Details]
Malone KM, Gordon SV (2017) 'Mycobacterium tuberculosis Complex Members Adapted to Wild and Domestic Animals'. Advances in Experimental Medicine and Biology, 1019 :135-154. [DOI] [Details]
Malone, K. M., Farrell, D., Stuber, T. P., Schubert, O. T., Aebersold, R., Robbe-Austerman, S., Gordon, S. V. (2017) 'Updated Reference Genome Sequence and Annotation of Mycobacterium bovis AF2122/97'. Genome Announcements, 5 (14). Available Online [Details]
Correia, C. N., Nalpas, N. C., McLoughlin, K. E., Browne, J. A., Gordon, S. V., MacHugh, D. E., Shaughnessy, R. G. (2017) 'Circulating microRNAs as Potential Biomarkers of Infectious Disease'. Frontiers in Immunology, 8 :118. Available Online [Details]
Farrell, D., Jones, G., Pirson, C., Malone, K., Rue-Albrecht, K., Chubb, A. J., Vordermeier, M., Gordon, S. V. (2016) 'Integrated computational prediction and experimental validation identifies promiscuous T cell epitopes in the proteome of Mycobacterium bovis'. Microb Genom, 2 (8). Available Online [Details]
Avanzi, C., Del-Pozo, J., Benjak, A., Stevenson, K., Simpson, V. R., Busso, P., McLuckie, J., Loiseau, C., Lawton, C., Schoening, J., Shaw, D. J., Piton, J., Vera-Cabrera, L., Velarde-Felix, J. S., McDermott, F., Gordon, S. V., Cole, S. T., Meredith, A. L. (2016) 'Red squirrels in the British Isles are infected with leprosy bacilli'. Science, 354 (6313):744-747. Available Online [Details]
Rahim, Z., Thapa, J., Fukushima, Y., van der Zanden, A. G., Gordon, S. V., Suzuki, Y., Nakajima, C. (2016) 'Tuberculosis Caused by Mycobacterium orygis in Dairy Cattle and Captured Monkeys in Bangladesh: a New Scenario of Tuberculosis in South Asia'. Transboundary and Emerging Diseases, . Available Online [Details]
Malone, K. M., Gordon, S. V. (2016) 'Antibiotic Methylation: A New Mechanism of Antimicrobial Resistance'. Trends in Microbiology, 24 (10):771-2. Available Online [Details]
Auer, A., Vande Burgt, N. H., Abram, F., Barry, G., Fenton, O., Markey, B. K., Nolan, S., Richards, K., Bolton, D., De Waal, T., Gordon, S. V., O'Flaherty, V., Whyte, P., Zintl, A. (2017) 'Agricultural anaerobic digestion power plants in Ireland and Germany: policy and practice'. Journal of the Science of Food and Agriculture, 97 (3):719-723. Available Online [DOI] [Details]
Rue-Albrecht K, McGettigan PA, Hernández B, Nalpas NC, Magee DA, Parnell AC, Gordon SV, MacHugh DE (2016) 'GOexpress: an R/Bioconductor package for the identification and visualisation of robust gene ontology signatures through supervised learning of gene expression data'. BMC Bioinformatics, 17 :126. [DOI] [Details]
Shaughnessy RG, Farrell D;Riepema K;Bakker D;Gordon SV (2015) 'Analysis of Biobanked Serum from a Mycobacterium avium subsp paratuberculosis Bovine Infection Model Confirms the Remarkable Stability of Circulating miRNA Profiles and Defines a Bovine Serum miRNA Repertoire'. PLoS ONE, 10 (12). [DOI] [Details]
N¿¿ Cheallaigh C, Sheedy FJ;Harris J;Mu¿¿oz-Wolf N;Lee J;West K;McDermott EP;Smyth A;Gleeson LE;Coleman M;Martinez N;Hearnden CH;Tynan GA;Carroll EC;Jones SA;Corr SC;Bernard NJ;Hughes MM;Corcoran SE;O'Sullivan M;Fallon CM;Kornfeld H;Golenbock D;Gordon SV;O'Neill LA;Lavelle EC;Keane J (2016) 'A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling'. Immunity, 44 (2):368-379. [DOI] [Details]
Britton LE, Cassidy JP;O'Donovan J;Gordon SV;Markey B (2016) 'Potential application of emerging diagnostic techniques to the diagnosis of bovine Johne's disease (paratuberculosis)'. Veterinary Journal, 209 :32-39. [DOI] [Details]
Healy C, Golby P, MacHugh DE, Gordon SV (2016) 'The MarR family transcription factor Rv1404 coordinates adaptation of Mycobacterium tuberculosis to acid stress via controlled expression of Rv1405c, a virulence-associated methyltransferase'. Tuberculosis, 97 :154-162. [DOI] [Details]
Gordon SV (2015) '70th Anniversary Collection for the Microbiology Society: Microbiology'. Microbiology-Sgm, 161 (12):2265-2268. [DOI] [Details]
Killick KE, Magee DA, Park SD, Taraktsoglou M, Browne JA, Conlon KM, Nalpas NC, Gormley E, Gordon SV, MacHugh DE, Hokamp K (2014) 'Key Hub and Bottleneck Genes Differentiate the Macrophage Response to Virulent and Attenuated Mycobacterium bovis'. Frontiers in immunology, 5 . [DOI] [Details]
Rue-Albrecht K, Magee DA;Killick KE;Nalpas NC;Gordon SV;MacHugh DE (2014) 'Comparative functional genomics and the bovine macrophage response to strains of the mycobacterium genus'. Frontiers in Immunology, 5 . [DOI] [Details]
Farrell D, Shaughnessy RG;Britton L;MacHugh DE;Markey B;Gordon SV (2015) 'The Identification of Circulating MiRNA in Bovine Serum and Their Potential as Novel Biomarkers of Early Mycobacterium avium subsp paratuberculosis Infection'. PLoS ONE, 10 (7). [DOI] [Details]
Farrell D, Gordon SV (2015) 'Epitopemap: a web application for integrated whole proteome epitope prediction'. BMC Bioinformatics, 16 . [DOI] [Details]
Berg S, Schelling E;Hailu E;Firdessa R;Gumi B;Erenso G;Gadisa E;Mengistu A;Habtamu M;Hussein J;Kiros T;Bekele S;Mekonnen W;Derese Y;Zinsstag J;Ameni G;Gagneux S;Robertson BD;Tschopp R;Hewinson G;Yamuah L;Gordon SV;Aseffa A (2015) 'Investigation of the high rates of extrapulmonary tuberculosis in Ethiopia reveals no single driving factor and minimal evidence for zoonotic transmission of Mycobacterium bovis infection'. BMC Infectious Diseases, 15 . [DOI] [Details]
Nalpas NC, Magee DA;Conlon KM;Browne JA;Healy C;McLoughlin KE;Rue-Albrecht K;McGettigan PA;Killick KE;Gormley E;Gordon SV;MacHugh DE (2015) 'RNA sequencing provides exquisite insight into the manipulation of the alveolar macrophage by tubercle bacilli'. Scientific Reports, 5 . [DOI] [Details]
Magee DA, Conlon KM, Nalpas NC, Browne JA, Pirson C, Healy C, McLoughlin KE, Chen J, Vordermeier HM, Gormley E, MacHugh DE, Gordon SV (2014) 'Innate cytokine profiling of bovine alveolar macrophages reveals commonalities and divergence in the response to Mycobacterium bovis and Mycobacterium tuberculosis infection'. Tuberculosis, 94 (4):441-450. [DOI] [Details]
Bourke J, Brereton CF, Gordon SV, Lavelle EC, Scanlan EM (2014) 'The synthesis and biological evaluation of mycobacterial p-hydroxybenzoic acid derivatives (p-HBADs)'. Organic and Biomolecular Chemistry, 12 (7):1114-1123. [DOI] [Details]
Pandey SD, Choudhury M, Yousuf S, Wheeler PR, Gordon SV, Ranjan A, Sritharan M (2014) 'Iron-regulated protein HupB of Mycobacterium tuberculosis positively regulates siderophore biosynthesis and is essential for growth in macrophages'. Journal of Bacteriology, 196 (10):1853-1865. [DOI] [Details]
Dinan AM, Tong P, Lohan AJ, Conlon KM, Miranda-CasoLuengo AA, Malone KM, Gordon SV, Loftus BJ (2014) 'Relaxed selection drives a noisy noncoding transcriptome in members of the Mycobacterium tuberculosis complex'. mBio, 5 (4):1-14. [DOI] [Details]
McLoughlin KE, Nalpas NC, Rue-Albrecht K, Browne JA, Magee DA, Killick KE, Park SD, Hokamp K, Meade KG, O'Farrelly C, Gormley E, Gordon SV, MacHugh DE (2014) 'RNA-seq Transcriptional Profiling of Peripheral Blood Leukocytes from Cattle Infected with Mycobacterium bovis'. Frontiers in immunology, 5 . [DOI] [Details]
Vegh P, Foroushani AB, Magee DA, McCabe MS, Browne JA, Nalpas NC, Conlon KM, Gordon SV, Bradley DG, Machugh DE, Lynn DJ (2013) 'Profiling microRNA expression in bovine alveolar macrophages using RNA-seq'. Veterinary Immunology and Immunopathology, 155 (4):238-244. [DOI] [Details]
Lew JM, Mao C, Shukla M, Warren A, Will R, Kuznetsov D, Xenarios I, Robertson BD, Gordon SV, Schnappinger D, Cole ST, Sobral B (2013) 'Database resources for the tuberculosis community'. Tuberculosis, 93 (1):12-17. [DOI] Link to full text [Details]
Golby P, Nunez J, Witney A, Hinds J, Quail MA, Bentley S, Harris S, Smith N, Hewinson RG, Gordon SV (2013) 'Genome-level analyses of Mycobacterium bovis lineages reveal the role of SNPs and antisense transcription in differential gene expression'. BMC Genomics, 14 (1). [DOI] Link to full text [Details]
Firdessa R, Berg S, Hailu E, Schelling E, Gumi B, Erenso G, Gadisa E, Kiros T, Habtamu M, Hussein J, Zinsstag J, Robertson BD, Ameni G, Lohan AJ, Loftus B, Comas I, Gagneux S, Tschopp R, Yamuah L, Hewinson G, Gordon SV, Young DB, Aseffa A (2013) 'Mycobacterial lineages causing pulmonary and extrapulmonary tuberculosis, Ethiopia'. Emerging Infectious Diseases, 19 (3):460-463. [DOI] [Details]
Allen AR, Dale J, McCormick C, Mallon TR, Costello E, Gordon SV, Hewinson RG, Skuce RA, Smith NH (2013) 'The phylogeny and population structure of Mycobacterium bovis in the British Isles'. Infection, Genetics and Evolution, 20C :8-15. [DOI] [Details]
Nalpas, NC,Park, SDE,Magee, DA,Taraktsoglou, M,Browne, JA,Conlon, KM,Rue-Albrecht, K,Killick, KE,Hokamp, K,Lohan, AJ,Loftus, BJ,Gormley, E,Gordon, SV,MacHugh, DE (2013) 'Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro'. BMC Genomics, 14 . [DOI] [Details]
Gouzy, A,Nigou, J,Gilleron, M,Neyrolles, O,Tailleux, L,Gordon, SV (2013) 'Tuberculosis 2012: biology, pathogenesis and intervention strategies; an update from the city of light'. Research in Microbiology, 164 :270-280. [DOI] Link to full text [Details]
Pawlik A, Garnier G, Orgeur M, Tong P, Lohan A, Le Chevalier F, Sapriel G, Roux AL, Conlon K, Honoré N, Dillies MA, Ma L, Bouchier C, Coppée JY, Gaillard JL, Gordon SV, Loftus B, Brosch R, Herrmann JL. (2013) 'Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus'. Molecular Microbiology, . [Details]
Magee DA, Taraktsoglou M, Killick KE, Nalpas NC, Browne JA, Park SD, Conlon KM, Lynn DJ, Hokamp K, Gordon SV, Gormley E, MacHugh DE (2012) 'Global gene expression and systems biology analysis of bovine monocyte-derived macrophages in response to in vitro challenge with Mycobacterium bovis'. PLoS ONE, 7 (2). [DOI] [Details]
Sharkey, MA; O'Gara, JP; Gordon, SV; Hackenberg, F; Healy, C; Paradisi, F; Patil, S; Schaible, B; Tacke, M (2012) 'Investigations into the Antibacterial Activity of the Silver-Based Antibiotic Drug Candidate SBC3'. Antibiotics, 1 :25-28. [DOI] [Details]
Chen J, Uplekar S, Gordon SV, Cole ST. (2012) 'A point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strains'. PLoS ONE, . [DOI] [Details]
Rodriguez-Campos S, Schürch AC, Dale J, Lohan AJ, Cunha MV, Botelho A, De Cruz K, Boschiroli ML, Boniotti MB, Pacciarini M, Garcia-Pelayo MC, Romero B, de Juan L, Domínguez L, Gordon SV, van Soolingen D, Loftus B, Berg S, Hewinson RG, Aranaz A, Smith NH (2012) 'European 2--a clonal complex of Mycobacterium bovis dominant in the Iberian Peninsula'. Gene, 12 (4):866-872. [DOI] [Details]
Chen JM, Uplekar S, Gordon SV, Cole ST (2012) 'A Point Mutation in cycA Partially Contributes to the D-cycloserine Resistance Trait of Mycobacterium bovis BCG Vaccine Strains'. PLoS ONE, 7 (8). [DOI] Link to full text [Details]
Ussery DW, Gordon SV (2012) 'Two novel methods for using genome sequences to infer taxonomy'. Journal of Microbiology, 158 (Pt 6). [DOI] [Details]
Cadmus, S.I., Gordon, S.V., Hewinson, R.G., Smith, N.H.; (2011) 'Exploring the use of molecular epidemiology to track bovine tuberculosis in Nigeria: An overview from 2002 to 2004'. Veterinary Microbiology, 151 (1 - 2):133-138. [DOI] [Details]
Killick KE, Browne JA, Park SD, Magee DA, Martin I, Meade KG, Gordon SV, Gormley E, O'Farrelly C, Hokamp K, MacHugh DE (2011) 'Genome-wide transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis reveals suppression of host immune genes'. BMC Genomics, 12 . [DOI] [Details]
Smith, N.H., Berg, S., Dale, J., Allen, A., Rodriguez, S., Romero, B., Matos, F., Ghebremichael, S., Karoui, C., Donati, C., Machado, Ada. C., Mucavele, C., Kazwala, R.R., Hilty, M., Cadmus, S., Ngandolo, B.N., Habtamu, M., Oloya, J., Muller, A., Milian-Suazo, F., Andrievskaia, O., Projahn, M., Barandiarán, S., Macías, A., Müller, B., Zanini, M.S,. Ikuta, C.Y., Rodriguez, C.A., Pinheiro, S.R., Figueroa, A., Cho, S.N., Mosavari, N., Chuang, P.C., Jou, R., Zinsstag, J., van Soolingen, D., Costello, E., Aseffa, A., Proaño-Perez, F., Portaels, F., Rigouts, L., Cataldi, A.A, Collins, D.M., Boschiroli, M.L., Hewinson, R.G., Ferreira Neto, J.S., Surujballi, O., Tadyon, K., Botelho, A., Zárraga, A.M., Buller, N., Skuce, R., Michel, A., Aranaz, A., Gordon, S.V., Jeon, B.Y., Källenius, G., Niemann, S., Boniotti, M.B., van Helden, P.D., Harris, B., Zumárraga, M.J., Kremer, K.; (2011) 'European 1: a globally important clonal complex of Mycobacterium bovis'. Infection Genetics And Evolution, 11 (6):1340-1351. [Details]
Vordermeier, M., Gordon, S.V., Hewinson, R.G.; (2011) 'Mycobacterium bovis antigens for the differential diagnosis of vaccinated and infected cattle'. Veterinary Microbiology, 151 (1-2):8-13. [DOI] [Details]
Jones GJ, Gordon SV, Hewinson RG, Vordermeier HM; (2010) 'Screening of Predicted Secreted Antigens from Mycobacterium bovis Reveals the Immunodominance of the ESAT-6 Protein Family'. Infection and Immunity, . [DOI] [Details]
Ameni G, Vordermeier M, Firdessa R, Aseffa A, Hewinson G, Gordon SV, Berg S; (2010) 'Mycobacterium tuberculosis infection in grazing cattle in central Ethiopia'. Veterinary Journal, . [DOI] [Details]
Schiller I, Vordermeier HM, Waters WR, Kyburz A, Cagiola M, Whelan A, Palmer MV, Thacker TC, Meijlis J, Carter C, Gordon S, Egnuni T, Hardegger R, Marg-Haufe B, Raeber A, Oesch B; (2010) 'Comparison of tuberculin activity using the interferon-gamma assay for the diagnosis of bovine tuberculosis'. Veterinary Record, 167 (9):322-326. [DOI] [Details]
Ojo OO, Sheehan S, Corcoran DG, Nikolayevsky V, Brown T, O'Sullivan M, O'Sullivan K, Gordon SV, Drobniewski F, Prentice MB; (2010) 'Molecular epidemiology of Mycobacterium tuberculosis clinical isolates in Southwest Ireland'. Infection Genetics And Evolution, . [DOI] [Details]
Mendoza Lopez P, Golby P, Wooff E, Garcia JN, Garcia Pelayo MC, Conlon K, Gema Camacho A, Hewinson RG, Polaina J, Suárez García A, Gordon SV; (2010) 'Characterisation of the transcriptional regulator Rv3124 of Mycobacterium tuberculosis identifies it as a positive regulator of molybdopterin biosynthesis and defines the functional consequences of a nonsynonymous SNP in the Mycobacterium bovis BCG orthologue'. Microbiology, . [DOI] Link to full text [Details]
Whelan AO, Coad M, Cockle PJ, Hewinson G, Vordermeier M, Gordon SV; (2010) 'Revisiting host preference in the Mycobacterium tuberculosis complex: experimental infection shows M. tuberculosis H37Rv to be avirulent in cattle'. PLoS ONE, 5 (1). [DOI] [Details]
Santangelo Mde L, Klepp L, Nunez-GarcÃia J, Blanco FC, Soria M, Garcia-Pelayo Mdel C, Bianco MV, Cataldi AA, Golby P, Jackson M, Gordon SV, Bigi F.; (2009) 'Mce3R, a TetR-type transcriptional repressor, controls the expression of a regulon involved in lipid metabolism in Mycobacterium tuberculosis'. Microbiology, 155 (Pt 7):2245-2255. [DOI] [Details]
Blanco FC, Nunez-García J, García-Pelayo C, Soria M, Bianco MV, Zumárraga M, Golby P, Cataldi AA, Gordon SV, Bigi F; (2009) 'Differential transcriptome profiles of attenuated and hypervirulent strains of Mycobacterium bovis'. Microbes and Infection, 11 (12):956-963. [DOI] [Details]
Chavadi S, Wooff E, Coldham NG, Sritharan M, Hewinson RG, Gordon SV, Wheeler PR; (2009) 'Global effects of inactivation of the pyruvate kinase gene in the Mycobacterium tuberculosis complex'. Journal of Bacteriology, 191 (24):7545-7553. [DOI] [Details]
Garcia Pelayo MC, Uplekar S, Keniry A, Mendoza Lopez P, Garnier T, Nunez Garcia J, Boschiroli L, Zhou X, Parkhill J, Smith N, Hewinson RG, Cole ST, Gordon SV; (2009) 'A comprehensive survey of single nucleotide polymorphisms (SNPs) across Mycobacterium bovis strains and M. bovis BCG vaccine strains refines the genealogy and defines a minimal set of SNPs that separate virulent M. bovis strains and M. bovis BCG strains'. Infection and Immunity, 77 (5):2230-2238. [DOI] [Details]
Vordermeier M, Gordon SV, Hewinson AR.; (2009) 'Antigen Mining to Define Mycobacterium bovis Antigens for the Differential Diagnosis of Vaccinated and Infected Animals: A VLA Perspective'. Transboundary and emerging diseases, 56 (6-7):240-247. [DOI] [Details]
Smith NH, Hewinson RG, Kremer K, Brosch R, Gordon SV.; (2009) 'Myths and misconceptions: the origin and evolution of Mycobacterium tuberculosis'. Nature reviews. Microbiology, 7 (7):537-544. [DOI] [Details]
Gordon SV, Bottai D, Simeone R, Stinear TP, Brosch R.; (2009) 'Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants'. BioEssays : news and reviews in molecular, cellular and developmental biology, . [DOI] [Details]
Muller, B,Hilty, M,Berg, S,Garcia-Pelayo, MC,Dale, J,Boschiroli, ML,Cadmus, S,Ngandolo, BNR,Godreuil, S,Diguimbaye-Djaibe, C,Kazwala, R,Bonfoh, B,Njanpop-Lafourcade, BM,Sahraoui, N,Guetarni, D,Aseffa, A,Mekonnen, MH,Razanamparany, VR,Ramarokoto, H,Djonne, B,Oloya, J,Machado, A,Mucavele, C,Skjerve, E,Portaels, F,Rigouts, L,Michel, A,Muller, A,Kallenius, G,van Helden, PD,Hewinson, RG,Zinsstag, J,Gordon, SV,Smith, NH; (2009) 'African 1, an Epidemiologically Important Clonal Complex of Mycobacterium bovis Dominant in Mali, Nigeria, Cameroon, and Chad'. Journal of Bacteriology, 191 :1951-1960. [DOI] [Details]
Berg S, Firdessa R, Habtamu M, Gadisa E, Mengistu A, Yamuah L, Ameni G, Vordermeier M, Robertson BD, Smith NH, Engers H, Young D, Hewinson RG, Aseffa A, Gordon SV.; (2009) 'The burden of mycobacterial disease in ethiopian cattle: implications for public health'. PLoS ONE, 4 (4). [DOI] [Details]
Golby P, Nunez J, Cockle PJ, Ewer K, Logan K, Hogarth P, Vordermeier HM, Hinds J, Hewinson RG, Gordon SV ; (2008) 'Characterization of two in vivo-expressed methyltransferases of the Mycobacterium tuberculosis complex: antigenicity and genetic regulation'. Microbiology, 154 (Pt 4):1059-1067. [DOI] [Details]
Gordon SV; (2008) 'Bovine TB: stopping disease control would block all live exports'. Nature, 456 (7223). [DOI] [Details]
Ojo O, Sheehan S, Corcoran GD, Okker M, Gover K, Nikolayevsky V, Brown T, Dale J, Gordon SV, Drobniewski F, Prentice MB; (2008) 'Mycobacterium bovis Strains Causing Smear-Positive Human Tuberculosis, Southwest Ireland'. Emerging infectious diseases, 14 (12):1931-1934. [Details]
Wheeler PR, Brosch R, Coldham NG, Inwald JK, Hewinson RG, Gordon SV; (2008) 'Functional analysis of a clonal deletion in an epidemic strain of Mycobacterium bovis reveals a role in lipid metabolism'. Microbiology, 154 (Pt 12):3731-3742. [DOI] [Details]
Garcia Pelayo MC, Garcia JN, Golby P, Pirson C, Ewer K, Vordermeier M, Hewinson RG, Gordon SV; (2008) 'Gene expression profiling and antigen mining of the tuberculin production strain Mycobacterium bovis AN5'. Veterinary microbiology, (NA). [DOI] [Details]
Ameni G, Aseffa A, Sirak A, Engers H, Young DB, Hewinson RG, Vordermeier MH, Gordon SV ; (2007) 'Effect of skin testing and segregation on the prevalence of bovine tuberculosis, and molecular typing of Mycobacterium bovis, in Ethiopia'. Veterinary Record, 161 (23):782-786. [Details]
Ameni G, Aseffa A, Engers H, Young D, Gordon S, Hewinson G, Vordermeier M; (2007) 'High prevalence and increased severity of pathology of bovine tuberculosis in Holsteins compared to zebu breeds under field cattle husbandry in central Ethiopia'. Vaccine, 14 (10):1356-1361. [DOI] [Details]
Golby P, Hatch KA, Bacon J, Cooney R, Riley P, Allnutt J, Hinds J, Nunez J, Marsh PD, Hewinson RG, Gordon SV ; (2007) 'Comparative transcriptomics reveals key gene expression differences between the human and bovine pathogens of the Mycobacterium tuberculosis complex'. Microbiology, 153 (Pt 10):3323-3336. [DOI] [Details]
Brosch R, Gordon SV, Garnier T, Eiglmeier K, Frigui W, Valenti P, Dos Santos S, Duthoy S, Lacroix C, Garcia-Pelayo C, Inwald JK, Golby P, Garcia JN, Hewinson RG, Behr MA, Quail MA, Churcher C, Barrell BG, Parkhill J, Cole ST ; (2007) 'Genome plasticity of BCG and impact on vaccine efficacy'. Proceedings of the National Academy of Sciences of the United States of America, 104 (13):5596-5601. [DOI] [Details]
Winder CL, Gordon SV, Dale J, Hewinson RG, Goodacre R; (2006) 'Metabolic fingerprints of Mycobacterium bovis cluster with molecular type: implications for genotype-phenotype links'. Microbiology, 152 (Pt 9):2757-2765. [DOI] [Details]
Ewer K, Cockle P, Gordon S, Mansoor H, Govaerts M, Walravens K, Marché S, Hewinson G, Vordermeier M ; (2006) 'Antigen mining with iterative genome screens identifies novel diagnostics for the Mycobacterium tuberculosis complex'. Vaccine, 13 (1):90-97. [DOI] [Details]
Cockle PJ, Gordon SV, Hewinson RG, Vordermeier HM; (2006) 'Field evaluation of a novel differential diagnostic reagent for detection of Mycobacterium bovis in cattle'. Vaccine, 13 (10):1119-1124. [DOI] [Details]
Smith NH, Gordon SV, de la Rua-Domenech R, Clifton-Hadley RS, Hewinson RG; (2006) 'Bottlenecks and broomsticks: the molecular evolution of Mycobacterium bovis'. Nature reviews. Microbiology, 4 (9):670-681. [DOI] [Details]
Cadmus S, Palmer S, Okker M, Dale J, Gover K, Smith N, Jahans K, Hewinson RG, Gordon SV; (2006) 'Molecular analysis of human and bovine tubercle bacilli from a local setting in Nigeria'. Journal of Clinical Microbiology, 44 (1):29-34. [DOI] [Details]
Hewinson RG, Vordermeier HM, Smith NH, Gordon SV; (2006) 'Recent advances in our knowledge of Mycobacterium bovis: a feeling for the organism'. Veterinary Microbiology, 112 (2-4):127-139. [DOI] [Details]
Smith NH, Kremer K, Inwald J, Dale J, Driscoll JR, Gordon SV, van Soolingen D, Hewinson RG, Smith JM ; (2006) 'Ecotypes of the Mycobacterium tuberculosis complex'. Journal of theoretical biology, 239 (2):220-225. [DOI] [Details]
Bigi F, Garcia-Pelayo MC, Nuñez-García J, Peralta A, Caimi KC, Golby P, Hinds J, Cataldi A, Gordon SV, Romano MI ; (2005) 'Identification of genetic markers for Mycobacterium pinnipedii through genome analysis'. Fems Microbiology Letters, 248 (2):147-152. [DOI] [Details]
Mostowy S, Inwald J, Gordon S, Martin C, Warren R, Kremer K, Cousins D, Behr MA; (2005) 'Revisiting the evolution of Mycobacterium bovis'. Journal of Bacteriology, 187 (18):6386-6395. [DOI] [Details]
Renshaw PS, Lightbody KL, Veverka V, Muskett FW, Kelly G, Frenkiel TA, Gordon SV, Hewinson RG, Burke B, Norman J, Williamson RA, Carr MD ; (2005) 'Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6'. Embo Journal, 24 (14):2491-2498. [DOI] [Details]
Cadmus S, Oluwasola A, Gordon SV; (2005) 'Molecular methods needed for the accurate assessment of Mycobacterium bovis infection'. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 9 (6). [Details]
Keating LA, Wheeler PR, Mansoor H, Inwald JK, Dale J, Hewinson RG, Gordon SV; (2005) 'The pyruvate requirement of some members of the Mycobacterium tuberculosis complex is due to an inactive pyruvate kinase: implications for in vivo growth'. Molecular Microbiology, 56 (1):163-174. [DOI] [Details]
Wheeler PR, Coldham NG, Keating L, Gordon SV, Wooff EE, Parish T, Hewinson RG; (2005) 'Functional demonstration of reverse transsulfuration in the Mycobacterium tuberculosis complex reveals that methionine is the preferred sulfur source for pathogenic Mycobacteria'. Journal of Biological Chemistry, 280 (9):8069-8078. [DOI] [Details]
Renshaw PS, Veverka V, Kelly G, Frenkiel TA, Williamson RA, Gordon SV, Hewinson RG, Carr MD; (2004) 'Sequence-specific assignment and secondary structure determination of the 195-residue complex formed by the Mycobacterium tuberculosis proteins CFP-10 and ESAT-6'. Journal of biomolecular NMR, 30 (2):225-226. [DOI] [Details]
Lightbody KL, Renshaw PS, Collins ML, Wright RL, Hunt DM, Gordon SV, Hewinson RG, Buxton RS, Williamson RA, Carr MD; (2004) 'Characterisation of complex formation between members of the Mycobacterium tuberculosis complex CFP-10/ESAT-6 protein family: towards an understanding of the rules governing complex formation and thereby functional flexibility'. Fems Microbiology Letters, 238 (1):255-262. [DOI] [Details]
Garcia-Pelayo MC, Caimi KC, Inwald JK, Hinds J, Bigi F, Romano MI, van Soolingen D, Hewinson RG, Cataldi A, Gordon SV; (2004) 'Microarray analysis of Mycobacterium microti reveals deletion of genes encoding PE-PPE proteins and ESAT-6 family antigens'. Tuberculosis (Edinburgh, Scotland), 84 (3-4):159-166. [DOI] [Details]
Kutalik Z, Inwald J, Gordon SV, Hewinson RG, Butcher P, Hinds J, Cho KH, Wolkenhauer O ; (2004) 'Advanced significance analysis of microarray data based on weighted resampling: a comparative study and application to gene deletions in Mycobacterium bovis'. Bioinformatics, 20 (3):357-363. [DOI] [Details]
Banu S, Gordon SV, Palmer S, Islam MR, Ahmed S, Alam KM, Cole ST, Brosch R; (2004) 'Genotypic analysis of Mycobacterium tuberculosis in Bangladesh and prevalence of the Beijing strain'. Journal of Clinical Microbiology, 42 (2):674-682. [Details]
Smith NH, Dale J, Inwald J, Palmer S, Gordon SV, Hewinson RG, Smith JM; (2003) 'The population structure of Mycobacterium bovis in Great Britain: clonal expansion'. Proceedings of the National Academy of Sciences of the United States of America, 100 (25):15271-15275. [DOI] [Details]
Inwald J, Jahans K, Hewinson RG, Gordon SV; (2003) 'Inactivation of the Mycobacterium bovis homologue of the polymorphic RD1 gene Rv3879c (Mb3909c) does not affect virulence'. Tuberculosis (Edinburgh, Scotland), 83 (6):387-393. [Details]
Stefanova T, Chouchkova M, Hinds J, Butcher PD, Inwald J, Dale J, Palmer S, Hewinson RG, Gordon SV; (2003) 'Genetic composition of Mycobacterium bovis BCG substrain Sofia'. Journal of Clinical Microbiology, 41 (11). [Details]
Carr MD, Bloemink MJ, Dentten E, Whelan AO, Gordon SV, Kelly G, Frenkiel TA, Hewinson RG, Williamson RA; (2003) 'Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease'. Journal of Biological Chemistry, 278 (44):43736-43743. [DOI] [Details]
Inwald J, Hinds J, Palmer S, Dale J, Butcher PD, Hewinson RG, Gordon SV; (2003) 'Genomic analysis of Mycobacterium tuberculosis complex strains used for production of purified protein derivative'. Journal of Clinical Microbiology, 41 (8):3929-3932. [Details]
Garnier T, Eiglmeier K, Camus JC, Medina N, Mansoor H, Pryor M, Duthoy S, Grondin S, Lacroix C, Monsempe C, Simon S, Harris B, Atkin R, Doggett J, Mayes R, Keating L, Wheeler PR, Parkhill J, Barrell BG, Cole ST, Gordon SV, Hewinson RG; (2003) 'The complete genome sequence of Mycobacterium bovis'. Proceedings of the National Academy of Sciences of the United States of America, 100 (13):7877-7882. [DOI] [Details]
Cockle PJ, Gordon SV, Lalvani A, Buddle BM, Hewinson RG, Vordermeier HM; (2002) 'Identification of novel Mycobacterium tuberculosis antigens with potential as diagnostic reagents or subunit vaccine candidates by comparative genomics'. Infection and Immunity, 70 (12):6996-7003. [Details]
Inwald J, Hinds J, Dale J, Palmer S, Butcher P, Hewinson RG, Gordon SV; (2002) 'Microarray-Based Comparative Genomics: Genome Plasticity in Mycobacterium bovis'. Genomics, 3 (4):342-344. [DOI] [Details]
Renshaw PS, Panagiotidou P, Whelan A, Gordon SV, Hewinson RG, Williamson RA, Carr MD; (2002) 'Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications for pathogenesis and virulence'. Journal of Biological Chemistry, 277 (24):21598-21603. [DOI] [Details]
Wooff E, Michell SL, Gordon SV, Chambers MA, Bardarov S, Jacobs WR Jr, Hewinson RG, Wheeler PR; (2002) 'Functional genomics reveals the sole sulphate transporter of the Mycobacterium tuberculosis complex and its relevance to the acquisition of sulphur in vivo'. Molecular Microbiology, 43 (3):653-663. [Details]
Gordon SV, Brosch R, Eiglmeier K, Garnier T, Hewinson RG, Cole ST; (2002) 'Royal Society of Tropical Medicine and Hygiene Meeting at Manson House, London, 18th January 2001. Pathogen genomes and human health. Mycobacterial genomics'. Transactions of the Royal Society of Tropical Medicine and Hygiene, 96 (1):1-6. [Details]
Brosch R, Gordon SV, Marmiesse M, Brodin P, Buchrieser C, Eiglmeier K, Garnier T, Gutierrez C, Hewinson G, Kremer K, Parsons LM, Pym AS, Samper S, van Soolingen D, Cole ST; (2002) 'A new evolutionary scenario for the Mycobacterium tuberculosis complex'. Proceedings of the National Academy of Sciences of the United States of America, 99 (6):3684-3689. [DOI] [Details]
Brosch R, Pym AS, Gordon SV, Cole ST; (2001) 'The evolution of mycobacterial pathogenicity: clues from comparative genomics'. Trends in microbiology, 9 (9):452-458. [Details]
Gordon SV, Eiglmeier K, Garnier T, Brosch R, Parkhill J, Barrell B, Cole ST, Hewinson RG; (2001) 'Genomics of Mycobacterium bovis'. Tuberculosis (Edinburgh, Scotland), 81 (1-2):157-163. [DOI] [Details]
Brosch R, Gordon SV, Pym A, Eiglmeier K, Garnier T, Cole ST; (2000) 'Comparative genomics of the mycobacteria'. International Journal of Medical Microbiology, 290 (2):143-152. [Details]
Brosch R, Gordon SV, Buchrieser C, Pym AS, Garnier T, Cole ST; (2000) 'Comparative genomics uncovers large tandem chromosomal duplications in Mycobacterium bovis BCG Pasteur'. Yeast, 17 (2):111-123. [DOI] [Details]
Brosch R, Gordon SV, Eiglmeier K, Garnier T, Cole ST; (2000) 'Comparative genomics of the leprosy and tubercle bacilli'. Research in Microbiology, 151 (2):135-142. [Details]
Tekaia F, Gordon SV, Garnier T, Brosch R, Barrell BG, Cole ST; (1999) 'Analysis of the proteome of Mycobacterium tuberculosis in silico'. Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 79 (6):329-342. [Details]
Brosch R, Philipp WJ, Stavropoulos E, Colston MJ, Cole ST, Gordon SV; (1999) 'Genomic analysis reveals variation between Mycobacterium tuberculosis H37Rv and the attenuated M. tuberculosis H37Ra strain'. Infection and Immunity, 67 (11):5768-5774. [Details]
Gordon SV, Brosch R, Billault A, Garnier T, Eiglmeier K, Cole ST; (1999) 'Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays'. Molecular Microbiology, 32 (3):643-655. [Details]
Gordon SV, Heym B, Parkhill J, Barrell B, Cole ST; (1999) 'New insertion sequences and a novel repeated sequence in the genome of Mycobacterium tuberculosis H37Rv'. Microbiology, 145 ( Pt 4) :881-892. [Details]
Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE 3rd, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream MA, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Squares S, Sulston JE, Taylor K, Whitehead S, Barrell BG; (1998) 'Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence'. Nature, 393 (6685):537-544. [DOI] [Details]
Brosch R, Gordon SV, Billault A, Garnier T, Eiglmeier K, Soravito C, Barrell BG, Cole ST; (1998) 'Use of a Mycobacterium tuberculosis H37Rv bacterial artificial chromosome library for genome mapping, sequencing, and comparative genomics'. Infection and Immunity, 66 (5):2221-2229. [Details]
O'Brien LM, Gordon SV, Roberts IS, Andrew PW; (1996) 'Response of Mycobacterium smegmatis to acid stress'. Fems Microbiology Letters, 139 (1):11-17. [Details]
Gordon S, Andrew PW; (1996) 'Mycobacterial virulence factors'. Society for Applied Bacteriology symposium series, 25 :1-1. [Details]
Gordon S, Houldsworth S, Duncan K, Roberts IS, Andrew PW; (1996) 'Rapid measurement of antimycobacterial drug activity'. Research in Microbiology, 147 (1-2):79-86. [Details]
Gordon S, Parish T, Roberts IS, Andrew PW; (1994) 'The application of luciferase as a reporter of environmental regulation of gene expression in mycobacteria'. Letters in applied microbiology, 19 (5):336-340. [Details]


Behr MA, Gordon SV (2014) Why doesn't Mycobacterium tuberculosis spread in animals?. Comment [DOI] [Details]


Research Interests

The Mycobacterium tuberculosis complex encompasses the aetiological agents of tuberculosis in mammals. My current focus is on the exploitation of the genome sequence of human pathogen, Mycobacterium tuberculosis, and the bovine pathogen, Mycobacterium bovis, to accelerate vaccine and diagnostic development. We are also exploring improved diagnostics for Johne's disease in cattle, caused by Mycobacterium avium subsp paratuberculosis

Research Projects

Sponsor : Dept. Agriculture, Food and the Marine (DAFM)
Title : Next generation approaches to improved diagnostics and molecular epidemiology for control of Mycobacterium avium subsp. paratuberculosis (NexusMAP)
Start Date / End Date : 01-JUN-17 / 31-MAY-21
Sponsor : Irish Research Council (IRC)
Title : ONE-TB: The study of bovine tubercolosis through a One Health approach
Start Date / End Date : 06-FEB-18 / 05-FEB-19
Sponsor : Consejo Nacional de Ciencia y Tecnología (Mexico)
Title : Assessment of the anti-mycobacterial efficacy and macrophage immunomodulatory function of novel bovine host defense peptides
Start Date / End Date : 01-JAN-18 / 31-DEC-18
Sponsor : HORIZON 2020
Title : Veterinary Biocontained facility Network for excellence in animal infectiology research and experimentation (VETBIONET)
Start Date / End Date : 01-MAR-17 / 28-FEB-22
Sponsor : Biotechnology and Biological Sciences Research Council (BBSRC)
Title : Defining the molecular basis of host-pathogen interaction in bovine TB
Start Date / End Date : 01-SEP-16 / 31-AUG-19
Sponsor : Science Foundation Ireland (SFI)
Title : Development of Next-Generation Control Tools for Bovine Tuberculosis: A One Health Approach
Start Date / End Date : 01-SEP-16 / 01-SEP-21
Sponsor : Science Foundation Ireland (SFI)
Title : Bilateral BBSRC-SFI: Tackling a multi-host pathogen problem - phylodynamic analyses of the epidemiology of M. bovis in Britain and Ireland
Start Date / End Date : 01-APR-17 / 01-APR-20
Sponsor : Science Foundation Ireland (SFI)
Title : High throughput transcriptomics for animal disease, including zoonosis
Start Date / End Date : 01-JAN-16 / 31-DEC-16
Sponsor : Science Foundation Ireland (SFI)
Title : H2020 Catalyst Award: Development of Next- Generation Control Tools for Bovine Tuberculosis: A One Health Approach
Start Date / End Date : 01-DEC-15 / 01-DEC-17
Sponsor : Irish Research Council (IRC)
Title : Next generation diagnostics for Johne's disease in cattle
Start Date / End Date : 01-OCT-15 / 30-SEP-17
Sponsor : HORIZON 2020
Title : Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical development (TBVAC2020)
Start Date / End Date : 01-JAN-15 / 31-DEC-18
Sponsor : Science Foundation Ireland (SFI)
Start Date / End Date : 01-SEP-13 / 28-FEB-14
Sponsor : Science Foundation Ireland (SFI)
Title : SFI Internship Award
Start Date / End Date : 04-MAR-13 / 03-MAR-14
Sponsor : Dept. Agriculture, Food and the Marine (DAFM)
Title : Multidisciplinary programme to deliver improved diagnosis, on-farm strategies, and economic drivers for the control of Mycobacterium avium subsp. paratuberculosis on Irish farms.
Start Date / End Date : 01-NOV-12 / 31-JAN-18
Sponsor : Dept. of Agriculture, Fisheries & Food (DAFF)
Start Date / End Date : 01-JUN-12 / 31-DEC-15
Sponsor : Higher Education Authority (HEA)
Title : PRTLI 5: MolCellBiol
Start Date / End Date : 01-MAR-11 / 31-DEC-16
Sponsor : Science Foundation Ireland (SFI)
Title : Functional genomics and proteomics studies of bovine tuberculosis
Start Date / End Date : 01-SEP-09 / 31-AUG-15
Sponsor : EC Framework (FP7)
Title : Novel secretion systems of Myco bacterium tuberculosis and their role in host pathogen interaction (NOVSEC-TB)
Start Date / End Date : 01-JAN-08 / 30-JUN-11

Recent Postgraduates

Current Postgraduate Students

Viktor Perets, Doctor of Philosophy (PhD)   -   Thesis Supervisor
Jose Maria Urtesun-Elizari, Doctor of Philosophy (PhD)   -   Thesis Supervisor
Susana Flores Villalva, Doctor of Philosophy (PhD)   -   Thesis Supervisor
Ruoyao Ma, Doctor of Philosophy (PhD)   -   Thesis Supervisor
Agathe Auer, Doctor of Philosophy (PhD)   -   Secondary Supervisor
Sarah Faherty O¿Donnell, Doctor of Philosophy (PhD)   -   Thesis Co-Supervisor
Carolina Neves Correia, Doctor of Philosophy (PhD)   -   Secondary Supervisor
Thomas Hall, Doctor of Philosophy (PhD)   -   Secondary Supervisor
Morgane Mitermite, Doctor of Philosophy (PhD)   -   Thesis Supervisor


Teaching Philosophy

Director of Thematic Doctoral Programme in Infection Biology.

Systems Microbiology (INDM40090)

Genomics and Proteomics (BMOL30050)

Intro Veterinary Microbiology (VET30030)

Advances in Infection Biology (VET40080)

Current Concepts in Infection Biology A (VET40090)

Current Concepts in Infection Biology B (VET40100)




External Collaborators

Prof. Ed Lavelle, Trinity College, Dublin.

Dr Max Gutierrez, Francis Crick Institute, London, UK.   

Dr Apoorva Bhatt, University of Birmingham, UK.  

Prof Nathalie Winter, Dr Aude Remot, INRA Tours, France.

Prof Roland Brosch, Institute Pasteur, Paris, France.    
Prof. Martin Vordermeier, Dr Bernardo Villarreal-Ramos, AHPHA Weybridge, Surrey, UK. 
Prof Rowland Kao, University of Edinburgh, UK.   
Dr Kieran Meade, Teagasc, Grange, Ireland.  
Prof Carlos Martin, Universidad de Zaragoza, Spain.  
Prof Abraham Aseffa, AHRI, Ethiopia.  
Prof Yasuhiko Suzuki and Dr Chie Nakajima, Hokkaido University, Japan.