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School of Chemical & Bioprocess Engineering

Artificial hip infection brought to life. Image by PhD student John Cotter.

Artificial hip infection brought to life. Image by PhD student John Cotter.

School of Chemical & Bioprocess Engineering - Research Publications 2005/06

Below is the list of research publications for the School of Chemical & Bioprocess Engineering in the academic year 2005/06




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Books

Chaudhuri, J. and Al-Rubeai, M. . Bioreactors for Tissue Engineering. Dordrecht : Springer.

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Book Chapters

Stubenrauch, C. and Rippner-Blomqvist, B. (2006) Chapter 11: Foam Films, Foams and Surface Rheology of Non-Ionic Surfactants: Amphiphilic Block Copolymers Compared with Low Molecular Weight Surfactants  in Colloid Stability: The Role of Surface Forces, Part 1, Tadros, T ed(s)., Wiley-VCH : Weinheim.

McDonnell, S., Murray, D., Hughes, L. and Redmond, A. (2006) Molecular Aspects of Cancer Invasion Chapter 3 in The Molecular and Cellular Pathology of Cancer Progression and Prognosis, Sherbet, G.V ed(s). : Research Signpost.

Murray, M., Gorreta, F., Grant, G., Vikas, C. and McDonnell, S. (2006) The investigation of tumour metastasis using cDNA microarrays, Chapter 1 in Bioarrays: from basics to diagnostics, Appasani, K ed(s)., Humana Press : Totowa, NJ:.

Warnock, J., Bratch, K. and Al-Rubeai, M. . (2005) Packed bed bioreactors in Bioreactors for Tissue Engineering, Chaudhuri, J. and Al-Rubeai, M ed(s)., Springer : Dordrecht.

Warnock, J. and Al-Rubeai, M. (2005) Production of biologics from animal cell cultures in Applications of Cell Immobilisation Biotechnology. Series: Focus on Biotechnology, Nedovic, Viktor, Willaert, Ronnie ed(s)., Springer : Dordrecht.

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Peer Reviewed Journals

Schulze-Schlarmann, J., Buchavzov, N.,Stubenrauch, C. (2006) A disjoining pressure study of foam films stabilized by tetradecyl trimethylammonium bromide C14TAB, in Soft Matter, 2, 584-594.

Warnock, J. N. and Al-Rubeai, M. (2006) Bioreactor systems for the production of biopharmaceuticals from animal cells in Biotechnology and Applied Biochemistry, 45, 1-12.

Warnock, J. N., Merten, O-W, Al-Rubeai, M. (2006) Cell culture processes for the production of viral vectors for gene therapy purposes in Cytotechnology, 50, 141-162.

Frank, C., Strey, R., Schmidt, C., and Stubenrauch, C. (2006) Coexisting lamellar phases in water – oil – surfactant systems induced by the addition of an amphiphilic block copolymer, in J. Colloid Interface Sci, DOI: 10.1016, (available online)

Varade, D. , Kunieda, H., Strey, R., Stubenrauch, C. (2006) Disconnected lamellar phases (La) in pseudobinary water – non-ionic surfactant systems: a general phenomenon, in J. Colloid Interface Sci, 300, 338-347.

Kowalczyk, P., MacElroy, J.M.D. (2006) Equilibrium Properties of Dense Hydrogen Isotope Gases Based on the Theory of Simple Fluids in J. Phys. Chem. B, 110, (30) 14971-14975.

Melero Martin, J. M., Dowling, M-A, Smith, M., Al-Rubeai, M. (2006) Expansion of chondroprogenitor cells on macroporous microcarriers as an alternative to conventional monolayer systems in Biomaterials, 27, 2970-2979.

Purdue, M.J., MacElroy, J.M.D., O’Shea, D.F., Okuom, M.O., Blum, F.D. (2006) Molecular dynamics of polystyrene solutions in microwave fields in J. Chem. Phys, 124, (2) Art. No. 204904

Blunk, D., Bierganns, P., Bongartz, N., Tessendorf, R., Stubenrauch, C. (2006) New Surfactants Made of Natural Compounds (Invited Review), in New J. Chem, DOI: 10.1039/b610045g, (available online)

Naciri, M. and Al-Rubeai, M. (2006) Non-invasive flow cytometric monitoring of pHi in cell culture processes using EGFP in Journal of Immunological Methods, 315, 185-190.

Shah, D., Naciri, M., Clee, P., Al-Rubeai, M. (2006) Nucleocounter- An efficient technique for the determination of cell number and viability in animal cell culture processes in Cytotechnology, 51, 39-44.

Melero Martin, J. M., Dowling, M-A., Smith, M., Al-Rubeai, M. (2006) Optimal In-Vitro Expansion of Chondroprogenitor Cells In Monolayer Culture in Biotechnology and Bioengineering, 93, 519-533.

Crea, F., Sarti, D., Falciani, F., Al-Rubeai, M. (2006) Over-expression of hTERT in CHO K1 results in decreased apoptosis and reduced serum dependency in Journal of Biotechnology, 121, 109-123.

Claesson, P. , Kjellin, M., Rojas, O., Stubenrauch, C. (2006) Short-range interactions between non-ionic surfactant layers , in PCCP, DOI: 10.1039, (available online)

Grigoriev, D., Stubenrauch, C. (2006) Surface elasticities of aqueous -dodecyl-D-maltoside solutions: a capillary wave study, in Colloids Surfaces A, DOI:10.1016/j.colsurfa.2006.09.025  , (available online)

Cuffe, L., MacElroy, J.M.D., Tacke, M., Kozachok, M., Mooney, D.A. (2006) The development of nanoporous membranes for separation of carbon dioxide at high temperatures in J.Membrane Sci, 272, ((1-2)) 6-10.

Faulkner, E., Barrett, M., Okor, S., Kieran, P., Casey, E., Paradisi, F., Engel, P., Glennon, B. (2006) Use of fed-batch cultivation for achieving high cell densities for the pilot-scale production of a recombinant protein (phenylalanine dehydrogenase) in Escherichia coli in Biotechnology Progress, 22, (3) 889-897.

Stubenrauch, C., Fainerman, V.B., Aksenenko, E.V., Miller, R. (2005) Adsorption behaviour and dilatational rheology of the cationic alkyl trimethylammonium bromides at the water/air interface in J. Phys. Chem. B, 109, (4) 1505-1509.

Hughes, L., Malone, C., O'Brien, S., Gallagher, W.M. and McDonnell, S. (2005) Development, characterisation and gene expression profiling of a novel more invasive variant established from the human breast cancer cell line Hs578T in European Journal of Cancer, S3, 88-89.

Tey, B. T. and Al-Rubeai, M. (2005) Effect of Bcl-2 overexpression on cell cycle and antibody productivity in chemostat cultures of myeloma NS0 cells in Journal of Bioscience and Bioengineering, 100, (3) 303-310.

Veraitch, F. S. and Al-Rubeai, M. (2005) Enhanced growth in NS0 cells expressing aminoglycoside phosphotransferase is associated with changes in metabolism, productivity and apoptosis in Biotechnology and Bioengineering, 92, 589-599.

Stubenrauch, C. (2005) Gut verpackt? Neue Verpackungsmaterialien für Lebensmittel in Chem. Unserer Zeit, 39, (5) 310-316.

Frank, C., Sottmann, T., Stubenrauch, C., Allgaier, J., Strey, R. (2005) Influence of amphiphilic block copolymers on lyotropic liquid crystals in water - oil - surfactant systems in Langmuir, 21, (20) 9058-9067.

Rojas, O.J., Stubenrauch, C., Schulze-Schlarmann, J., Claesson, P.M. (2005) Interactions Between Non-Polar Surfaces Coated with the Non-Ionic Surfactant Dodecyl-b-D-maltoside  in Langmuir, 21, (25) 11836-11843.

Suh, S.-H., J.W. Lee, Moon, H. and MacElroy, J.M.D. . (2005) Molecular dynamics studies of two particles in a rectangular box: Hard-sphere and square-well interactions in Adsorption-J. Int. Adsorption Soc, 11, 373-378.

Gallagher, W.M., Bergin, O.E., Rafferty, M., Kelly, Z.D., Nolan, I.M., Fox, E.J.P., Culhane, A.E., McArdle, L., Fraga, M.F., Hughes, L., Currid, C.A., O’Mahony, F., Byrne, A., Murphy, A.A., Moss, C., McDonnell, S., Stallings, R.L., Plumb, J.A., Esteller, M., Brown, B., Dervan, P.A. and Easty, D.J. . (2005) Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies in Carcinogenesis, 26, (11) 1856-1867.

Stubenrauch, C., Strey, R. (2005) New Equation of State for Thin Foam Films in J. Phys. Chem. B, 109, (42) 19798-19805.

Tey, B. T. and Al-Rubeai, M. (2005) Protective effect of Bcl-2 in NS0 myeloma cell culture is greater in more stressful environments in Biotechnology and Bioprocess Engineering, 10, 564-570.

Schulze-Schlarmann, J., Stubenrauch, C., Miller, R. (2005) Revision of the adsorption behavior of the non-ionic surfactant tetraoxyethylen decylether C10E4 at the water/air interface  in Tenside Surf. Det, 42, (5) 307-313.

O'Sullivan, B. and Glennon, B. . (2005) The Application of In Situ FBRM and ATR-FTIR to the Monitoring of the Polymorphic Transformation of D-Mannitol in Organic Process Research and Development, 9, (6) 884-889.

Syron, E., Casey, E. (2005) Towards a deterministic model of biofilm detachment: an experimental study in Biofilms, 2, (4) 254-255.study in Biofilms, 2, (4) 254-255.

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Other Journals

O'Grady, D., Barrett, M., Casey, E.., Glennon, B. (2006) The PAT toolbox for production scale-crystallization in Pharmaceutical Manufacturing, 5, (6) 44-47.

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Reports

Stubenrauch, C. (2006) Book Review on L.L. Schramm, Emulsions, Foams and Suspensions - Fundamentals and Applications, Wiley-VCH, Weinheim 2005, 448 pp., ISBN 3-527-30743-5, Weinheim, Germany : Wiley VCH.

Connellan, L. and 15 co-authors (Al-Rubeai, M.). (2005) Engineering a Knowledge Island 2020, Dublin : Engineers Ireland.

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Conference Publications

Al-Rubeai, M. (2006) Biopharmaceutical manufacturing processes: Engineering and selection of cell lines for optimised production. 1st International conference on Natural Resources, Engineering and Technology, Putrajaya, Malaysia (July 24-25 2006)

Barrett, M., O'Grady, D., Glennon, B. . (2006) Characterisation of anti-solvent addition crystallisation using in situ tools. 2006 International Real Time Analytics Users' Conference, Barcelona, Spain (26 February - 1 March 2006)

Close C.E., Gleeson M.R., Kelly J.V., O'Neill F.T., Mooney D., Sheridan J.T. (2006) Determination of diffusion rates in Acrylamide-based photopolymer material. PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS - 2nd Conference on Photon Management, Strasbourg, France (3-4 April 2006)

Al-Rubeai, M. (2006) Development of cell lines for controlled proliferation and apoptosis. IBC conference “Cell Line Development and Engineering”, Zurich (23-24 May 2006)

Varade, D., Aramaki, K., Kunieda, H., Strey, R., Stubenrauch, C. . (2006) Disconnected Lamellar Phases in Pseudobinary Water – Non-Ionic Surfactant Systems: A General Phenomenon. 16th International Symposium on Surfactants in Solution, Seoul, Korea (4.-Sept.-6.2006)

Buchavzov, N., Stubenrauch, C. (2006) Disjoining Pressure of Thin Foam Films – Single Surfactants compared to Surfactant Mixtures. Eufoam 2006, Potsdam, Germany (2.-July-7.2006)

Crea, F. and Al-Rubeai, M. (2006) Does telomerase over-expression enhance chromosomal stability and possibly production stability?. Cell Culture Engineering X, Whistler, Canada (23-28 June 2006)

Hughes, L., Malone, C., O'Brien, S., Gallagher, W.M. and McDonnell, S. (2006) Expression of candidate invasion-specific genes, PLAC8, CTAG1B, Lumican and Decorin in human cancer cell lines. Irish Association for Cancer Research Annual Meeting, Galway, Ireland (March 3rd-4th)

Stubenrauch, C., Santini, E., Ravera, F., Ferrari, M., Makievski, A., Krägel, J. . (2006) Factors that determine the Stability of Foam Films - Disjoining Pressure versus Surface Rheology. Eufoam 2006, Potsdam, Germany (2.-7.7.2006)

Malone, C., Hughes, L., Gallagher, W.M. and McDonnell, S. (2006) Identification and expression analysis of candidate markers of breast cancer invaison. 19th European Association for Cancer Research, Budapest, Hungary (July 1st-4th)

Khoo, S. H. G. and Al-Rubeai, M. (2006) Industrial applications of transcriptomic and metabolic profiling: deciphering recombinant protein productivity in proliferation arrested mouse myeloma NS0 cells. th European Symposium on Biochemical Engineering Science, Salzburg, Austria (27-30 August 2006)

Redmond, A., Gray, I., Nolan, K. and McDonnell, S. (2006) Investigation of novel 5-fluorouracil derivatives for gene-directed enzyme prodrug therapy using the nitroreductase enzyme. Irish Association for Cancer Research Annual Meeting, Galway, Ireland (March 3rd-4th)

Malone, C., Hughes, L., Gallagher, W.M. and McDonnell, S. (2006) Investigation of potential markers of breast cancer invasion. EMBO Molecular Medican Conference. Common Molecular Mechanisms of Mammary Gland Developmet and Breast Cancer Progression, Dublin, Ireland (June 6th-8th)

Heffernan, B. (2006) Investigation of the effect of respiratory location in a stratified Pseudomonas fluorescens biofilm on overall activity for an inhibitory substrate. Microbial Bioconversions: Biocatalysis and Biodegradation, Society for General Microbiology, Irish Branch Meeting, Dublin, Ireland (31st August to 1st September 2006)

Heffernan, B., Phelan, S., Murphy, C., Casey, E. (2006) Investigation of the interactions between biological and physico-chemical processes in a Pseudomonas fluorescens biofilm. Recent Advances in Chemical Biology IV, Dublin, Ireland (2 December 2005)

Tessendorf, R., Strey, R., Stubenrauch, C., Blunk, D. (2006) Lamellar Phases and Microemulsions in Water-Oil-Surfactant Systems: Alkyldimethyl Phosphine Oxides compared to Alkyldiethyl Phosphine Oxides. 34. Arbeitstagung Flüssigkristalle, Freiburg, Germany (29.-31.3.2006)

Astley, K. L., Khoo, G., Clee, P., Kuystermans, D., Al-Rubeai, M. (2006) Modulation of p21, bcl-2 and c-myc genes for enhanced adaptation to suspension and serum free culture of mammalian cell lines. Cell Culture Engineering X, Whistler, Canada (23-28 June 2006)

Stubenrauch, C., Strey, R. (2006) New Equation of State for Thin Foam Films. 105. Bunsentagung, Erlangen, Germany (25. – 27.5.2006)

Redmond, A., Gray, I., Nolan, K. and McDonnell, S. (2006) Novel 5-Fluorouracil pro-drug derivatives. EMBO Molecular Medican Conference. Common Molecular Mechanisms of Mammary Gland Developmet and Breast Cancer Progression, Dublin, Ireland (June 6th-8th)

Krampe, B. and Al-Rubeai, M. (2006) Proteomic analysis of antibody producing NS0 cells cultivated in high density perfusion culture. 6th European Symposium on Biochemical Engineering Science, Salzburg, Austria (27-30 August 2006)

Woolley, J. and Al-Rubeai, M. (2006) Rapid protein profiling and biomarker identification in mammalian cell culture using SELDI-TOF-based approach. Cell Culture Engineering X, Whistler, Canada (23-28 June 2006)

Buchavzov, N., Stubenrauch, C. (2006) Surface Tension and Disjoining Pressure of Surfactant Mixtures. 105. Bunsentagung, Erlangen, Germany (25. – 27.5.2006)

Bongartz, N., Blunk, D., Buchavzov, N., Stubenrauch, C. (2006) Synthesis and Selected Properties of New Inositol Surfactants . 34. Arbeitstagung Flüssigkristalle, Freiburg, Germany (29.-31.3.2006)

Syron, E. and Casey, E. (2006) Towards a deterministic model of biofilm detachment: an experimental study. Biofilms II - Attachment and Detachment in Pure and Mixed Cultures, Leipzig, Germany (March 23-24, 2006)

Rojas, O.J., Stubenrauch, C., Claesson, P.M. (2006) Viscoelasticity and Surface Forces in Systems with Alkyl Polyglycoside Surfactants. International Workshop on Bridging Nanoscale Forces and Interfacial Phenomena to the Macroscopic World, Cancun, Mexiko (7.-12.5.2006)

O'Grady, D. and Glennon, B. (2005) Characterisation of Anti-solvent Addition Crystallization Using In-Line Tools. British Association for Crystal Growth Annual Conference, Sheffield, UK (September 4-7 2005)

Cuffe, L., MacElroy, J.M.D., Tacke, M., and Mooney, D.A. (2005) Development of nanoporous membranes for gas separation at high temperature. 10th Irish Inorganic Chemistry Conference, Maynooth, Ireland (10-11 September 2005)

Buchavzov, N., Stubenrauch, C., Khristov, Kh. (2005) Foams and Foam Films stabilized by CnTAB: influence of the chain length and of impurities. 42nd Meeting of the German Colloid Society, Aachen, Germany (26.-28.9.2005)

Hughes, L. and McDonnell, S. (2005) Gene expression profiling of human breast cancers within an Irish population using DNA microarrays. Irish Research Council for Science, Engineering and Technology, Third Annual Symposium, Dublin, Ireland (November 3rd)

Kozachok, M., and MacElroy, J.M.D. (2005) Novel membranes for high temperature separation of CO2 from combustion exhaust gases. 3rd Symposium of the Irish Research Council for Science, Engineering and Technology, Dublin, Ireland (3 November, 2005)

Faulkner, E., Barrett, M., Okor, S., Paradisi, F., Engel, P. and Glennon, B. (2005) The use of fed batch cultivation for achieving high cell densities for the pilot scale production of a recombinant protein (Phenylalanine dehydrogenase) in Escherichia coli. AIChE Annual Meeting, Cincinnati, USA (October 30th - November 4th 2005)

O'Grady, D. and Glennon, B. (2005) Use of In-Situ Instrumention to Characterise Anti-solvent Addition Crystallization. AIChE Annual Meeting, Cincinnati, USA (October 30th - November 4th 2005)
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