Imperfect mixing in a bioreactor. Image by Dr Eoin Casey.
School of Chemical & Bioprocess Engineering - Research Publications 2006/07
Below is the list of research publications for the School of Chemical & Bioprocess Engineering in the academic year 2006/07
Click here to download as a PDF. (75 kbs)
| Professor Mohamed Al-Rubeai | |
Ifandi, V. and Al-Rubeai, M. (2007) 'Engineering of Cell Proliferation via myc Modulation' In: Al-Rubeai, M. and Fussenegger, M (eds). Cell Engineering vol. 5. Systems Biology. London: Springer.  |
|
| Khoo, S.H.G. and Al-Rubeai, M. (2007) 'Metabolomics' In: Al-Rubeai, M. and Fussenegger, M (eds). Cell Engineering vol. 5. Systems Biology. London: Springer. |
|
| Carroll S., Naciri M., Al-Rubeai, M. (2007) 'Monitoring of growth, physiology and productivity of animal cells by flow cytometry' In: R. Portner (eds). Animal Cell Biotechnology, Methods and Protocols. Methods in Biotechnology, vol 24. New Jersey, USA: Humana Press. |
|
| Ishaque, A. and Al-Rubeai, M. (2007) 'Measurement of apoptosis in cell culture' In: Portner, R (eds). Animal Cell Biotechnology, Methods and Protocols. Methods in Biotechnology, vol 24. New Jersey, USA: Humana Press. |
|
| Melero-Martin, J. M. and Al-Rubeai, M. (2007) 'In vitro expansion of chrondrocytes' In: Ashammakhi, N., Reis, R.L. and Chiallini, E (eds). Topics in Tissue Engineering, Vol 3. internet: E-book: Biomaterials and Tissue Engineering Group. |
|
| Professor Mohamed Al-Rubeai | |
| Al-Rubeai, M and Fussenegger, Martin (Ed.). (2007) Cell Engineering Vol. 5: Systems Biology. London: Springer. |
|
| Professor Mohamed Al-Rubeai | |
| Sandhu, K.S., Naciri, M. and Al-Rubeai, M. (2007) 'Prediction of recombinant protein production in an insect cell-baculovirus system using a flow cytometric technique'. Journal of Immunological Methods, 325 (1-2):104-113. | |
| Khoo, S.H.G. and Al-Rubeai, M. (2007) 'Metabolomics as a complementary tool in cell culture'. Biotechnology and Applied Biochemistry, 47 :71-84. | |
| Astley, K., Naciri, M., Racher, A., and Al-Rubeai, M. (2007) 'The role of p21(cip1) in adaptation of CHO cells to suspension and protein-free culture'. Journal of Biotechnology, 130 (3):282-290. | |
| Majid, F. A. A., Butler, M., and Al-Rubeai, M. (2007) 'Glycosylation of an immunoglobulin produced from a murine hybridoma cell line: The effect of culture mode and the anti-apoptotic gene, bcl-2'. Biotechnology and Bioengineering, 97 (1):156-169. | |
| Turner, P., Petch, A., and Al-Rubeai, M. (2007) 'Encapsulation of viral vectors for gene therapy applications'. Biotechnology Progress, 23 (2):423-429. | |
| Kuystermans, D., Krampe, B., Swiderek, H., Al-Rubeai, M. (2007) 'Using cell engineering and omic tools for the improvement of cell culture processes'. Cytotechnology, 53 :3-22. | |
| O'Connor, K.C., Muhitch, J.W., Lacks, D.J., Al-Rubeai, M. (2006) 'Modeling suppression of cell death by Bcl-2 over-expression in myeloma NSO 6A1 cells'. Biotechnology Letters, 28 (23):1919-1924. | |
| Dr Eoin Casey | |
| O’Grady, D., Barrett, M., Casey, E and Glennon B. (2007) 'The Effect of Mixing on the Metastable Zone Width and Nucleation Kinetics in the Anti-Solvent Crystallization of Benzoic Acid'. Chemical Engineering Research and Design, Transactions, 85 (A7):945-952. |
|
| Dr Niall J English | |
| English, N.J. (2007) 'Calculation of Binding Affinities of HIV-1 RT and Secretase Inhibitors Using the Linear Interaction Energy Method with Explicit and Continuum Solvation Approaches'. Journal of Molecular Modeling, 13 (10):1081-1097. | |
| Taylor, C.E., Link, D.D., and English, N.J (2007) 'Methane Hydrate Research at NETL: Research to Make Methane Production from Hydrates a Reality'. J. Petrol. Sci. & Eng, 56 (1-3):186-191. | |
| English, N.J. and Mooney, D.A. (2007) 'Denaturation of hen egg white lysozyme in electromagnetic fields: a molecular dynamics study'. Journal of Chemical Physics, 126 (9):091105-091105. | |
| English, N.J., Sorescu, D.C and Johnson, J.K (2006) 'Effects of an external electromagnetic field on rutile TiO2: a molecular dynamics study'. J. Phys. Chem. Solids, 67 :1399-1409. | |
| English, N.J. (2006) 'Molecular Dynamics Simulations of Microwave Effects on Water Using Different Long-Range Electrostatics Methodologies'. Molecular Physics, 104 (2):243-253. | |
| Dr Brian Glennon | |
| O'Grady, D., Barrett, M., Casey, E., Glennon, B. (2007) 'The effect of mixing on the metastable zone width and nucleation kinetics in the anti-solvent crystallization of benzoic acid'. Chemical Engineering Research and Design, Transactions, 85 (A7):945-952. | |
| Dr Patricia Mary Kieran | |
| Jeffers, P., Kerins, S., Baker, CJ., Kieran, PM. (2007) 'Generation of reactive oxygen and antioxidant species by hydrodynamically stressed suspensions of Morinda citrifolia'. Biotechnology Progress, 23 (1):138-145. | |
| Dr Maria Raytchinova Kosseva | |
| Panesar, P.S., Kennedy, J.F., Knill, C.J. and Kosseva, M. (2007) 'Applicability of pectate entrapped Lactobacillus casei cells for L(+) lactic acid production from whey'. Applied Microbiology and Biotechnology, 74 :35-42. | |
| Kosseva, M.R., Fatmawati, A., Palatova, M., Kent, C.A. (2007) 'Modelling thermophilic cheese whey bioremediation in a one-stage process'. Biochemical Engineering Journal, 35 :281-288. | |
| Kendall K. and Kosseva M.R. (2006) 'Nanoparticle aggregation influenced by magnetic field'. Colloids and Surfaces A: Physicochem. Eng. Aspects, 286 :112-116. | |
| Professor Donal MacElroy | |
| Kowalczyk, P., Solarz, L., Do, DD., Samborski, A., MacElroy, JMD. (2006) 'Nanoscale tubular vessels for storage of methane at ambient temperatures'. Langmuir, 22 (21):9035-9040. | |
| Purdue, MJ., MacElroy, JMD., O'Shea, DF., Okuom, MO., Blum, FD. (2006) 'A comparative study of the properties of polar and nonpolar solvent/solute/polystyrene solutions in microwave fields via molecular dynamics'. Journal of Chemical Physics, 125 (11 Art No. 114902). | |
| Dr Susan McDonnell | |
| Hughes L., O’Brien SL., Gallagher W.M. and McDonnell, S. (2007) 'DNA microarray-based transcriptomic profiling of an isogenic cell culture model of breast tumour cell invasion'. Anticancer Research, 27 :3-9. | |
| McDonnell, S., Hughes, L., Malone, C. (2007) 'Microarray analysis of invasion in human cancer cells in vitro'. AntiCancer Research, 27 ((3A)):1371-1372. | |
| Dr Damian Mooney | |
| English, N.J., Mooney, D.A. (2007) 'Denaturation of hen egg white lysozyme in electromagnetic fields: A molecular dynamics study'. Journal of Chemical Physics, 126 (9):Art. No. 091105-091105. | |
| Dr Cosima Stubenrauch | |
| Buchavzov, N., Ravera, F., Hess, S., Liu, Y., Steinbrenner, U., Stubenrauch, C. (2007) 'Interfacial Tensions, Partition Coefficients, and Interfacial Elasticities: Measures for Emulsion Stability?'. Tenside Surf. Det, 44 (230). | |
| Varade, D., Aramaki, K., Stubenrauch, C. (2007) 'Phase Diagrams of Water - Alkyltrimethylammonium Bromide Systems'. Colloids and Surfaces A, DOI:10.1016/j.colsurfa.2007.07.031 . | |
| Blunk, D., Tessendorf, R., Buchavzov, N., Strey, R., Stubenrauch, C. (2007) 'Purification, Surface Tensions, and Miscibility Gaps of Alkyldimethyl and Alkyldiethyl Phosphine Oxides'. Journal of Surfactants and Detergents, 10 (155). | |
| Stubenrauch, C., Tessendorf, R., Strey, R., Lynch, I., Dawson, K. (2007) 'Gelled Polymerisable Microemulsions - Part I: Phase Behavior'. Langmuir, 23 (7730). | |
| Frank, C., Strey, R., Schmidt, C., Stubenrauch, C. (2007) 'Coexisting lamellar phases in water - oil - surfactant systems induced by the addition of an amphiphilic block copolymer (Invited Article)'. Journal of Colloid and Interface Science, 312 (76). | |
| Buchavzov, N., Stubenrauch, C. (2007) 'A Disjoining Pressure Study of Foam Films Stabilized by Mixtures of Nonionic and Ionic Surfactants'. Langmuir, 23 (5315). | |
| Grigoriev, D., Stubenrauch, C. (2007) 'Surface elasticities of aqueous n-dodecyl-beta-D-maltoside solutions: a capillary wave study'. Colloids and Surfaces A, 296 (67). | |
| Angarska, J., Stubenrauch, C., Manev, E. (2007) 'Drainage of Foam Films stabilized with Mixtures of Non-ionic Surfactants'. Colloids and Surfaces A, 309 (189). | |
| Santini, E., Ravera, F., Ferrari, M., Stubenrauch, C., Makievski, A., Krägel, J. (2007) 'A surface rheological study of non-ionic surfactants at the water-air interface and the stability of the corresponding thin foam films'. Colloids and Surfaces A, 298 (12). | |
| Stubenrauch, C., Cohen, R., Exerowa, D. (2007) 'A pH-Study of n-Dodecyl-beta-D-maltoside Foam Films'. Langmuir, 23 (1684). | |
| Blunk, D., Bierganns, P., Bongartz, N., Tessendorf, R., Stubenrauch, C. (2006) 'New Speciality Surfactants with Natural Structural Motifs (Invited Review)'. New Journal of Chemistry, 30 (1705). | |
| Claesson, P.M., Kjellin, M., Rojas, O.J., Stubenrauch, C. (2006) 'Short-range interactions between non-ionic surfactant layers (Invited Review)'. Physical Chemistry Chemical Physics, 8 (5501). | |
| Professor Mohamed Al-Rubeai | |
| Buckler A. and Al-Rubeai, M. (2007) The effect of genetically modified insulin growth factor on cell proliferation and adenovirus productivity in serum free medium. In: Cell Technology for Cell Products. Springer, London. Smith R eds. 19th ESACT Meeting, Harrowgate UK, 619 - 622. |
|
| Crea, F., Sarti D., Falciani F., Al-Rubeai, M. (2007) Growth, Apoptosis and Functional Genomics Analysis of CHO-K1 Over-Expressing Telomerase. In: Cell Technology for Cell Products. Springer, London. Smith R eds. 19th ESACT Meeting, Harrowgate UK, 41 - 45. |
|
| Ifandi, V. and Al-Rubeai, M. (2007) Influence of c-myc and bcl-2 co-expression on proliferation, apoptosis and survival of CHO cultures. In: Cell Technology for Cell Products. Springer, London. Smith R eds. 19th ESACT Meeting, Harrowgate UK, 217 - 220. |
|
| Clee, P. and Al-Rubeai, M. (2007) Media and cell manipulation approaches to the reduction of adaptation time in GS NS0 cell line. In: Cell Technology for Cell Products. Springer, London. Smith R eds. 19th ESACT Meeting, 381 - 383. |
|
| Khoo, G., Falciani, F., Al-Rubeai, M. (2007) Microarray analysis of metabolically engineered NS0 cell lines producing chimeric antibody. In: Cell Technology for Cell Products. Springer, London. Smith R eds. 19th ESACT Meeting, Harrowgate UK, 47 - 52. |
|
| Astley, K. L. and Al-Rubeai, M. (2007) Adaptation without cell division? Enhanced adaptation to suspension and serum free culture by the co-expression of p21 and Bcl-2. In: Cell Technology for Cell Products. Springer, London. Smith R eds. 19th ESACT Meeting, 107 - 110. |
|
| Sandhu, K. S. and Al-Rubeai, M. (2007) Flow cytometry as a tool for process monitoring of virus-cell systems. In: Cell Technology for Cell Products. Springer, London. Smith R eds. 19th ESACT Meeting, 571 - 573. |
|
| Melero-Martin J., Santhalingam S., Al-Rubeai, M. (2007) Large-scale expansion of cells for use as therapeutic agents. In: Cell Technology for Cell Products. Springer, London. Smith R eds. 19th ESACT Meeting, Harrowgate UK, 335 - 338. |
|
| Veraitch F. and Al-Rubeai, M. (2007) The expression of the neo gene in GS-NS0 cells increases their proliferative capacity. In: Cell Technology for Cell Products. Springer, London. Smith R eds. 19th ESACT Meeting, Harrowgate UK, 157 - 162. |
|
| Al-Rubeai, M. (2007) Deciphering Increased Antibody Productivity in Proliferation-Arrested NS0 Myeloma Cells. Biochemical Engineering XV: Engineering Biology from Biomolecules to Complex Systems, Quebec Canada. | |
| Al-Rubeai, M., Swiderek H., Krampe, B. (2007) Quantatitive genomic and proteomic analysis of NS0 cells in high density perfusion cultures. Biochemical Engineering XV: Engineering Biology from Biomolecules to Complex Systems, Quebec Canada. | |
| Khoo, S. H. G. and Al-Rubeai, M. (2007) Toward a system-level understanding of increased specific productivity in proliferation arrested myeloma NS0 cells. ESACT meeting, Dresden. | |
| Kuystermans D. and Al-Rubeai, M. (2007) Differential protein expression induced by c-myc over-expression: proteomic analysis of a CHO cell line with increased proliferation capacity. ESACT meeting, Dresden. | |
| Swiderek, H. and Al-Rubeai, M. (2007) Transcriptome analysis of the effect of hypothermia and hypoxia. ESACT meeting, Dresden. | |
| Krampe, B., Swiderek H., Al-Rubeai, M. (2007) Transcriptome and proteome analysis of monoclonal antibody producing NS0 cells in high cell density perfusion culture. ESACT meeting, Dresden. | |
| Shah, D., Clee, P., Boisen, S., Al-Rubeai, M. (2007) NucleoCounter – An efficient technique for the determination of Cell Number and Viability in Animal Cell Culture Processes. In: Cell Technology for Cell Products. Springer, London. Smith R eds. 19th ESACT Meeting, Harrowgate UK, 535 - 538. |
|
| Al-Rubeai, M. (2007) Cell engineering of industrial cell lines for bioprocessing. 2nd Annual Cell Line development and Engineering, Renaissance Penta Vienna, Austria. | |
| Al-Rubeai, M. (2006) Cell line engineering for controlled proliferation and apoptosis. Japanese Association for Animal Cell Technology, Kyoto Japan. | |
| Swiderek, H. and Al-Rubeai, M. (2006) Transcriptome analysis of antibody producing NS0 cell line cultivated at sub-physiological temperatures. Global mRNA and protein expression analysis, DCU Ireland. | |
| Kuystermans, D. and Al-Rubeai, M. (2006) Proteomic analysis of differential protein expression induced by c-Myc over-expression in CHO cells. Global mRNA and protein expression analysis, DCU Ireland. | |
| Al-Rubeai, M. (2006) Applications of expression and metabolic profiling in cell culture. Global mRNA and protein expression analysis, DCU Dublin. | |
| Krampe, B. and Al-Rubeai, M. (2006) Transcriptomic and proteomic analysis of antibody producing NS0 cells cultivated in high density perfusion culture. Global mRNA and protein expression analysis, DCU Ireland. | |
| Dr Eoin Casey | |
| Cotter, John J., O'Gara, James P., Stewart, Philip S., Pitts, Betsey, Casey, Eoin (2007) Contribution of oxygen to Staphylococcus epidermidis biofilm development and antibiotic susceptibility. American Society for Microbiology, Biofilms 2007, Quebec, Canada, 172 - 173. | |
| Syron, Eoin, Casey, Eoin (2007) Characterization of biofilm detachment using a novel bioreactor. American Society for Microbiology, Biofilms 2007, Quebec, Canada, 141 - 141. | |
| Casey, E. (2007) Simulation st udies of process scale membrane aerated biofilm reactor configurations. 4th International Water Association Membranes Conference, Harrogate, UK | |
| Heffernan, Barry, Bryan, Una, Murphy, Cormac, Casey, Eoin (2007) Investigation of the effect of 2-fluorobenzoate on respiratory location in a stratified Pseudomonas fluorescens biofilm. American Society for Microbiology, Biofilms 2007, Quebec, Canada, 150 - 150. | |
| Barrett, M., O'Grady, D., Glennon, B., Casey, E. (2006) The application of CFD to the Multi-Scale Characterisation of Anti-Solvent Addition Crystallization. AIChE Annual Meeting, San Francisco, USA | |
| Syron, E. and, Casey, E. (2006) Dynamics of active layer stratification in a membrane-aerated biofilm. IWA Conference on Biofilm Systems VI, Amsterdam, the Netherlands. | |
| Heffernan, B., Phelan, S., Murphy, C., Casey, E. (2006) Investigation of the effect of respiratory location in a stratified Pseudomonas fluorescens biofilm on overall activity for an inhibitory substrate. IWA Conference on Biofilm Systems VI, Amsterdam, the Netherlands. | |
| Cotter, J.J., O’Gara J.P., Casey, E. (2006) Analysis of Staphylococcus epidermidis 1457 biofilm grown in a Rotating-Disk Reactor (RDR) under defined oxygen concentrations. International Symposium on Staphylococci & Staphylococcal Infections, Maastricht, The Netherlands. | |
| Dr Niall J English | |
| English, N.J. (2007) Denaturation of hen egg white lysozyme in electromagnetic fields: an MD study. Spring Meeting of the ACS, Chicago, Illinois. | |
| English, N.J. (2006) Application of the Linear Interaction Energy Method in Drug Design. SMI Drug Design Conference V, London, UK. | |
| Dr Brian Glennon | |
| Barrett, M., Casey E., Glennon, B. (2007) Anti-solvent crystallization scale-up: impact of addition profile, addition location and feed pipe diameter. 14th International Process Development Conference, Heidleberg, Germany. | |
| M. Barrett, O'Grady, D., Glennon, B. & Casey, E. (2006) The Application of CFD to the Multi-Scale Characterization of Anti-Solvent Addition Crystallization. AIChE Annual Meeting, San Francisco, USA. | |
| O'Grady, D., Barrett, M. & Glennon, B. (2006) Scale-up of Anti-Solvent Crystallization Using in Situ Tools and Computational Fluid Dynamics. AIChE Annual Meeting, San Francisco, USA. | |
| Dr Maria Raytchinova Kosseva | |
| Kosseva, M.R. (2007) Biosurfactant Production from Renewable Resources using Probiotic Bacteria. 10th International Congress on Amino Acids and Proteins, Kallithea, Greece, XIII - XIV. | |
| Professor Donal MacElroy | |
| Ramamoorthy, A., R., Rahman, M., Mooney, D.A., MacElroy, J.M.D., Dowling, D.P. (2007) Effect of process parameters on chemistry, growth rate and particle formation of atmospheric plasma deposited SiOx-siloxane coatings. Nanosmat2007 Conference, Portugal. | |
| McCann, M., Rahman, M., Mooney, D.A., Dowling, D., MacElroy, J.M.D. (2007) Growth of TiOx nano-films by PVD sputtering onto ceramic surfaces as a function of time for the preparation of high performance separation membranes. International Meeting on Developments in Materials, Processes and Applications of Nanotechnology, MPA-2007, Belfast, Northern Ireland. | |
| Ramamoorthy, A., R., Rahman, M., Mooney, D.A., MacElroy, J.M.D., Dowling, D.P. (2006) Atmospheric pressure plasma deposition of SiOx coatings on Vycor glass. International Conference on Technological Advances of Thin Films & Surface Coatings, OFN 606, Singapore. | |
| Deshmukh, S.A., Mooney, D.A., MacElroy, J.M.D. (2006) Molecular modelling of thermo-responsive hydrogels Macro-2006, Polymers for Advanced Technologies, Pune, India. | |
| Deshmukh, S.A., Mooney, D.A., MacElroy, J.M.D. (2006) Molecular simulation of pH sensitive hydrogels: structure generation, dynamics and solvent transport Macro-2006, Polymers for Advanced Technologies, Pune, India. | |
| McDermott, T.C., Kozachok, M., Akter, T., MacElroy, J.M.D., Mooney, D.A (2006) Atomistic Simulation of the Formation of Nanoporous Silica Films Via Chemical Vapor Deposition. AIChE National Annual Meeting, San Francisco, USA. | |
| Dr Damian Mooney | |
| English, N.J., Mooney, D.A. (2007) Denaturation of hen egg white lysozyme in electromagnetic fields: A molecular dynamics study. 7th International Conference on Nanoscience and Nanotechnology, Nanotech 2007, Santa Clara, USA. | |
| English, N.J., Mooney, D.A. (2007) Denaturation of hen egg white lysozyme in electromagnetic fields: A molecular dynamics study. American Chemical Society: Spring Meeting (2007), Chicago, IL, USA, March 25-29. | |
| McCann, M., Rahman, M., Mooney, D.A., Dowling, D., MacElroy, J.M.D. (2007) Growth of TiOx nano-films by PVD sputtering onto ceramic surfaces as a function of time for the preparation of high performance separation membranes. International Meeting on the Developments in Materials, Processes & Applications for Nanotechnology. | |
| Mooney, D.A., Deshmukh, S.M., MacElroy, J.M.D (2006) Molecular simulation of pH sensitive hydrogels: structure generation, dynamics and solvent transport. Proceedings of Macro-2006 (2006), The Society of Polymer Science, Pune, India, December 17-20. | |
| Mooney, D.A., Kulkarni, S., Deshmukh, S.M., MacElroy, J.M.D. (2006) Molecular modelling of thermo-responsive hydrogels Proceedings of Macro-2006 (2006), The Society of Polymer Science, Pune, India, December 17-20. | |
| Ramamoorthy, A., Rahman, M., Mooney, D.A., MacElroy, J.M.D, Dowling, D.P. (2006) Atmospheric pressure plasma deposition of SiOx coatings on Vycor glass Thin Films 2006, Proceedings of 3rd Internation Conference on Technological Advances of Thin Films & Surface Coatings. | |
| Dr Cosima Stubenrauch | |
| Tessendorf, R., Stubenrauch, C., Lynch, I., Dawson, K., Strey, R. (2007) Microemulsions as Templates for New Materials Ostwald Kolloquium. | |
| Catanoiu, G., Stubenrauch, C., Blunk, D. (2007) Liquid crystalline amphiphilic phosphine oxide metal complexes 35. Arbeitstagung Flüssigkristalle. | |
| Stubenrauch, C. (2006) Factors that determine the Stability of Foam and Emulsion Films: Disjoining Pressure and Interfacial Rheology. World Congress of Emulsions. | |
